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Found results for
 patents
1.
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ACTIVITY OF RECOMBINANT EQUINE FOLLICLE STIMULATING HORMONE
| Document Number |
02707352 |
| Status |
In Force |
| Filing Date |
2008-11-28 |
| Open to Public Date |
2009-06-11 |
| Grant Date |
2020-10-27 |
| Owner |
ASPENBIO PHARMA, INC. (USA)
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| Inventor |
- Colgin, Mark
- Boime, Irving
- Roser, Janet
- Niswender, Kory
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Abstract
The present invention provides methods of producing biologically active recombinant eFSH analogs and methods of increasing reproduction in mammals, particularly equine, using recombinant eFSH analogs. Also provided are methods of producing biologically active single chain recombinant eFSH. The recombinant eFSH analogs of the present invention increase superovulation, follicular development, embryo development, and reproductive efficiency in horses, cattle and other ungulates.
IPC Classes ?
- C07K 14/59 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. hCG [human chorionic gonadotropin]Luteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- A61K 35/55 - Glands not provided for in groups , e.g. thyroids, parathyroids or pineal glands
- A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
- A61K 38/24 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. HCGLuteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- A61P 15/08 - Drugs for genital or sexual disordersContraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- C12N 15/16 - Hormones
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2.
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ACTIVITY OF RECOMBINANT EQUINE FOLLICLE STIMULATING HORMONE
| Application Number |
US2008085072 |
| Publication Number |
2009/073574 |
| Status |
In Force |
| Filing Date |
2008-11-28 |
| Publication Date |
2009-06-11 |
| Owner |
ASPENBIO PHARMA, INC. (USA)
|
| Inventor |
- Colgin, Mark
- Boime, Irving
- Roser, Janet
- Niswender, Kory
|
Abstract
The present invention provides methods of producing biologically active recombinant eFSH analogs and methods of increasing reproduction in mammals, particularly equine, using recombinant eFSH analogs. Also provided are methods of producing biologically active single chain recombinant eFSH. The recombinant eFSH analogs of the present invention increase superovulation, follicular development, embryo development, and reproductive efficiency in horses, cattle and other ungulates.
IPC Classes ?
- A61K 35/55 - Glands not provided for in groups , e.g. thyroids, parathyroids or pineal glands
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3.
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Methods for inducing superovulation in ungulates
| Application Number |
12028155 |
| Grant Number |
08518881 |
| Status |
In Force |
| Filing Date |
2008-02-08 |
| First Publication Date |
2008-12-18 |
| Grant Date |
2013-08-27 |
| Owner |
AspenBio Pharma, Inc. (USA)
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| Inventor |
- Colgin, Mark A.
- Donnelly, Richard G.
- Stroud, Brad
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Abstract
The present invention provides methods of producing biologically active recombinant bFSH and methods of increasing reproduction in mammals, particularly bovine, using recombinant bFSH. Also provided are methods of producing single chain recombinant bFSH. The recombinant bFSH of the present invention increases superovulation, embryo development, and reproductive efficiency in cattle and other ungulates.
IPC Classes ?
- A61K 38/24 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. HCGLuteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- C07K 14/59 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. hCG [human chorionic gonadotropin]Luteinising hormone [LH]Thyroid-stimulating hormone [TSH]
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4.
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METHODS AND DEVICES FOR DIAGNOSIS OF APPENDICITIS
| Application Number |
US2008052418 |
| Publication Number |
2008/097773 |
| Status |
In Force |
| Filing Date |
2008-01-30 |
| Publication Date |
2008-08-14 |
| Owner |
ASPENBIO PHARMA, INC. (USA)
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| Inventor |
- Colgin, Mark, A.
- Bealer, John, F.
- Donnelly, Richard, G.
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Abstract
An immunoassay device and method is provided for determining the severity of appendicitis in a patient that includes testing a blood, serum or plasma sample from the patient for the quantity of MRP8/14 in the sample and comparing it with the quantity of MRP8/14 present in standard samples correlated with an appendicitis severity scoring system. Standard samples and data correlating MRP8/14 quantities present in patient samples to histologically-based appendicitis severity grades are also provided. The methods and immunoassay devices and kits of this invention are useful for managing the treatment of patients presenting with appendicitis symptoms.
IPC Classes ?
- C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
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5.
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COMPOSITIONS AND METHODS INCLUDING EXPRESSION AND BIOACTIVITY OF BOVINE FOLLICLE STIMULATING HORMONE
| Application Number |
US2008053417 |
| Publication Number |
2008/098169 |
| Status |
In Force |
| Filing Date |
2008-02-08 |
| Publication Date |
2008-08-14 |
| Owner |
- ASPENBIO PHARMA, INC. (USA)
- DONNELLY, Richard G. (USA)
- STROUD, Brad (USA)
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| Inventor |
Colgin, Mark A.
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Abstract
The present invention provides methods of producing biologically active recombinant bFSH and methods of increasing reproduction in mammals, particularly bovine, using recombinant bFSH. Also provided are methods of producing single chain recombinant bFSH. The recombinant bFSH of the present invention increases superovulation, embryo development, and reproductive efficiency in cattle and other ungulates.
IPC Classes ?
- A01K 67/02 - Breeding vertebrates
- A61K 38/24 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. HCGLuteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- C07K 14/59 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. hCG [human chorionic gonadotropin]Luteinising hormone [LH]Thyroid-stimulating hormone [TSH]
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6.
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COMPOSITIONS AND METHODS INCLUDING EXPRESSION AND BIOACTIVITY OF BOVINE FOLLICLE STIMULATING HORMONE
| Document Number |
02685437 |
| Status |
In Force |
| Filing Date |
2008-02-08 |
| Open to Public Date |
2008-08-14 |
| Grant Date |
2015-06-02 |
| Owner |
ASPENBIO PHARMA, INC. (USA)
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| Inventor |
- Colgin, Mark A.
- Donnelly, Richard G.
- Stroud, Brad
|
Abstract
The present invention provides methods of producing biologically active recombinant bFSH and methods of increasing reproduction in mammals, particularly bovine, using recombinant bFSH. Also provided are methods of producing single chain recombinant bFSH. The recombinant bFSH of the present invention increases superovulation, embryo development, and reproductive efficiency in cattle and other ungulates.
IPC Classes ?
- C07K 14/59 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. hCG [human chorionic gonadotropin]Luteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
- A61K 38/24 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. HCGLuteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- A61P 15/00 - Drugs for genital or sexual disordersContraceptives
- C12N 15/16 - Hormones
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7.
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Methods and kits for maintaining pregnancy, treating follicular cysts, and synchronizing ovulation using luteinizing hormone
| Application Number |
10795128 |
| Grant Number |
10105417 |
| Status |
In Force |
| Filing Date |
2004-03-04 |
| First Publication Date |
2004-12-30 |
| Grant Date |
2018-10-23 |
| Owner |
AspenBio Pharma, Inc. (USA)
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| Inventor |
- Mcsweeney, Kevin
- Colgin, Mark
- Newman, Diane
- Roth, Jay W.
- Hurst, Roger
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Abstract
This invention provides methods and kits for maintaining pregnancy in mammals. Pregnancy is maintained by administration of effective amounts of luteinizing hormone (LH) or chorionic gonadotropin (CG). Both LH and CG may be used alone, in combination with each other, or in combination with growth hormone (GH) or follicle stimulating hormone (FSH). Hormones are administered on about Day 4 to about Day 7 following insemination. Effective amounts of LH range from about 10 micrograms to about 25 milligrams, preferably about 2 to about 8 mg, and of CG range from about 100 IU (international units) to about 2000 IU. Mammals treatable by the methods of this invention include ungulates and related mammals, including bovines. Kits provided by this invention include effective amounts of one or more hormones, a device for administering the hormone(s) and instructions. This invention also provides methods for treating follicular cysts and for synchronizing ovulation in mammals using LH.
IPC Classes ?
- A61K 38/24 - Follicle-stimulating hormone [FSH]Chorionic gonadotropins, e.g. HCGLuteinising hormone [LH]Thyroid-stimulating hormone [TSH]
- A61D 19/00 - Instruments or methods for reproduction or fertilisation
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