Goods & Services

Drug delivery agents in the form of dissolvable film that facilitate the delivery of pharmaceutical preparations, nutraceuticals and dietary supplements, for medicinal and dental use; transbuccal patches, trans-mucosal patches, and patches containing pharmaceutical preparations for oral local release of pharmaceuticals, for use in the treatment of dry mouth, mouth ulcers, oral thrush, and mucositis; transbuccal patches, trans-mucosal patches, and oral adhesive patches for oral local release of medicated oral care preparations, vitamin preparations, bacteriostats, and nutraceuticals, for medicinal and dental use.

Goods & Services

Drug delivery agents in the form of dissolvable film that facilitate the delivery of pharmaceutical preparations, nutraceuticals and dietary supplements, for medicinal and dental use; transbuccal patches, trans-mucosal patches, and patches containing pharmaceutical preparations for oral local release of pharmaceuticals, for use in the treatment of dry mouth, mouth ulcers, oral thrush, and mucositis; transbuccal patches, trans-mucosal patches, and oral adhesive patches for oral local release of medicated oral care preparations, vitamin preparations, bacteriostats, and nutraceuticals, for medicinal and dental use

Abstract

Disclosed is a dissolvable film adapted to adhere to an oral mucosal tissue of a subject, wherein the film comprises at least three indigestible hydrophilic polymers constituting from 35% to 55% of the film dry weight and wherein the at least three polymers comprise xanthan gum and carboxymethyl cellulose (CMC) in a weight ratio of between 1:0.8-1.6, and at least one other cellulose based polymer. Optionally, the film may further include an active agent in an amount of 0.01% to 35% of the film dry weight. Disclosed also is a method for preparing the film and a method for treating or preventing oral conditions comprising implementing the film. Particularly, the film may be applied between dentures and the gums of the user.

IPC Classes  ?

• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61K 47/38 - CelluloseDerivatives thereof
• A61K 9/70 - Web, sheet or filament bases
• A61Q 11/00 - Preparations for care of the teeth, of the oral cavity or of dentures, e.g. dentifrices or toothpastesMouth rinses
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 31/131 - Amines, e.g. amantadine acyclic
• A61K 6/35 - Preparations for stabilising dentures in the mouth
• A61K 36/889 - Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

Abstract

Disclosed is a dissolvable film adapted to adhere to an oral mucosal tissue of a subject, wherein the film comprises at least three indigestible hydrophilic polymers constituting from 35% to 55% of the film dry weight and wherein the at least three polymers comprise xanthan gum and carboxymethyl cellulose (CMC) in a weight ratio of between 1:0.8-1.6, and at least one other cellulose based polymer. Optionally, the film may further include an active agent in an amount of 0.01% to 35% of the film dry weight. Disclosed also is a method for preparing the film and a method for treating or preventing oral conditions comprising implementing the film. Particularly, the film may be applied between dentures and the gums of the user.

IPC Classes  ?

• A61K 47/38 - CelluloseDerivatives thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/70 - Web, sheet or filament bases
• A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient
• A61K 47/30 - Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Abstract

Provided are orally administrable thin film dosage forms adapted to adhere to a mucosal tissue of a patient, wherein said film comprises mixtures of polymers and insulin.

IPC Classes  ?

• A61K 38/28 - Insulins
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• C07K 14/62 - Insulins

Abstract

Provided are orally administrable thin film dosage forms adapted to adhere to a mucosal tissue of a patient, wherein said film comprises mixtures of polymers and insulin.

IPC Classes  ?

• A61F 13/00 - Bandages or dressingsAbsorbent pads