Physician's Seal, LLC

United States of America

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        Patent 6
        Trademark 1
Date
2020 1
Before 2020 6
IPC Class
A61K 9/20 - Pills, lozenges or tablets 5
A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin 3
A61K 36/84 - Valerianaceae (Valerian family), e.g. valerian 2
A61K 31/19 - Carboxylic acids, e.g. valproic acid 1
A61K 33/30 - ZincCompounds thereof 1
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Found results for

1.

SOLID MICRONIZED MELATONIN COMPOSITION

      
Application Number US2020014086
Publication Number 2020/150605
Status In Force
Filing Date 2020-01-17
Publication Date 2020-07-23
Owner PHYSICIAN'S SEAL, LLC (USA)
Inventor
  • Shah, Syed M.
  • Hassan, Daniel

Abstract

A melatonin composition has a dry granulation including a melatonin powder with a median melatonin particle size of 5 µm to 40 µm, a carboxylic acid powder, and a powder of a hydrogel-forming polymer. The dry granulation is combined with pharmaceutical excipients in a dry orally ingestible pharmaceutical dosage form adapted to absorb water upon ingestion and form a hydrogel including soluble melatonin and soluble carboxylic acid in the hydrogel, the carboxylic acid being in an amount sufficient to impart a pH of 4.4 or less to the hydrogel after ingestion.

IPC Classes  ?

  • A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/19 - Carboxylic acids, e.g. valproic acid

2.

ORALLY DISSOLVING MELATONIN FORMULATION WITH ACIDIFYING AGENT THAT RENDERS MELATONIN SOLUBLE IN SALIVA

      
Application Number US2018037698
Publication Number 2018/236678
Status In Force
Filing Date 2018-06-15
Publication Date 2018-12-27
Owner PHYSICIAN'S SEAL, LLC (USA)
Inventor
  • Shah, Syed M.
  • Hassan, Daniel
  • Hassan, Fred
  • Corsino, Patrick

Abstract

A composition includes a pharmaceutical dosage form configured to dinsintegrate in saliva and maintain a pH of 4 or less within the saliva during the time the dosage form is dissolving therein. The dosage form includes a therapeutically effective amount of melatonin in a carrier matrix, a disintegrant, and a sufficient amount of acid to impart the pH to the saliva. The amount of disintegrant is sufficient to cause the dosage form to completely disintegrate in the saliva within ten minutes from contacting the saliva.

IPC Classes  ?

  • A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/70 - Web, sheet or filament bases

3.

CONTROLLED-RELEASE COMPOSITIONS OF MELATONIN COMBINED WITH SEDATIVE AND/OR ANALGESIC INGREDIENTS

      
Application Number US2017031012
Publication Number 2018/106280
Status In Force
Filing Date 2017-05-04
Publication Date 2018-06-14
Owner PHYSICIAN'S SEAL, LLC (USA)
Inventor
  • Shah, Syed M.
  • Hassan, Daniel
  • Diorio, Christopher
  • Hassan, Fred

Abstract

Controlled-release therapeutic compositions including melatonin combined with sedative and/or analgesic ingredients are described. The compositions have a solid core including melatonin in an acidified polymeric matrix. A sedative ingredient such as a GABA receptor agonist may also be in the acidified polymeric matrix. The composition may include an expedited release portion providing a burst release of active ingredients and a sustained release portion providing a sustained release of active ingredients.

IPC Classes  ?

  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
  • A61K 36/76 - Salicaceae (Willow family), e.g. poplar
  • A61K 36/84 - Valerianaceae (Valerian family), e.g. valerian

4.

FLOATING ZINC GASTRIC DELIVERY COMPOSITIONS

      
Application Number US2017031007
Publication Number 2017/192818
Status In Force
Filing Date 2017-05-04
Publication Date 2017-11-09
Owner PHYSICIAN'S SEAL, LLC (USA)
Inventor
  • Hassan, Daniel
  • Shah, Syed, M.
  • Hassan, Fred
  • Diorio, Christopher

Abstract

A composition includes a therapeutically effective oral pharmaceutical dosage form that becomes buoyant upon contact with gastric fluid. The dosage form includes an active ingredient combination including an amino acid source and a zinc source, an anionic polymer, an effervescent agent, and a pH buffer. The dosage form is effective for releasing the active ingredient combination while buoyant on gastric fluid.

IPC Classes  ?

  • A61K 33/30 - ZincCompounds thereof
  • A61K 38/02 - Peptides of undefined number of amino acidsDerivatives thereof
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/46 - Pills, lozenges or tablets effervescent

5.

MULTIPARTICULATE L-CARNITINE AND NOOTROPIC COMPOSITIONS AND RELATED METHODS

      
Application Number US2017031022
Publication Number 2017/192828
Status In Force
Filing Date 2017-05-04
Publication Date 2017-11-09
Owner PHYSICIAN'S SEAL, LLC (USA)
Inventor
  • Shah, Syed M.
  • Diorio, Christopher
  • Hassan, Daniel
  • Hassan, Noreen
  • Hassan, Fred

Abstract

A composition includes a therapeutically effective pharmaceutical dosage form including a plurality of individual particulates. The individual particulates respectively have: a core including an active ingredient combination of an L-carnitine and a nootropic substance and a release controlling polymer over the core that substantially prevents release of the active ingredients in stomach acid and permits release of the active ingredients in an intestinal pH environment. The composition may be used to treat conditions associated with a reduction of the amount of L-carnitine in the body and/or cognitive impairment.

IPC Classes  ?

  • A61K 9/50 - Microcapsules
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets

6.

VALERIAN COMPOSITION AND RELATED METHODS

      
Application Number US2017031046
Publication Number 2017/192843
Status In Force
Filing Date 2017-05-04
Publication Date 2017-11-09
Owner PHYSICIAN'S SEAL, LLC (USA)
Inventor
  • Shah, Syed M.
  • Diorio, Christopher
  • Hassan, Daniel
  • Hassan, Fred

Abstract

A valerian composition includes a therapeutically effective pharmaceutical dosage form having a solid core including a polymer in which valerian and a valerian stability improving amount of an acidifying agent are contained. The valerian stability improving amount of acidifying agent being sufficient to impart a pH of 2 to 5 to the polymer.

IPC Classes  ?

  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 36/84 - Valerianaceae (Valerian family), e.g. valerian

7.

CALM THE RESTLESS MIND

      
Application Number 1337424A
Status Registered
Filing Date 2016-12-29
Registration Date 2016-12-29
Owner Physician's Seal, LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Dietary supplements; nutritional supplements; pharmaceutical preparations for use in treating sleep disorders; melatonin preparations for pharmaceutical purposes; valerian preparations for pharmaceutical purposes; over-the-counter pharmaceutical preparations for use in treating sleep disorders.