Abstract

Provided herein are supplements that include free amino acids L-glutamine or a salt thereof, L-leucine or a salt thereof, nd L-arginine or a salt thereof, and active IGF-1. The L-glutamine or salt thereof, L-leucine or salt thereof, and L-arginine or salt thereof can be present at a ratio of approximately 3:1:1. Also provided are compositions that include the supplement, such as a food product. The disclosure also includes, but is not limited to, methods for using the supplements, including improving the performance of an animal, improving a processing factor of an animal, or increasing intestinal health of an animal, where the method includes administering to the animal a food product that has the supplement.

IPC Classes  ?

• A23K 20/142 - Amino acidsDerivatives thereof
• A23K 20/184 - Hormones
• A23K 50/30 - Feeding-stuffs specially adapted for particular animals for swine
• A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry

Abstract

Provided herein are supplements that include free amino acids L-glutamine or a salt thereof, L-leucine or a salt thereof, and L-arginine or a salt thereof, and active IGF-1. The L-glutamine or salt thereof, L-leucine or salt thereof, and L-arginine or salt thereof can be present at a ratio of approximately 3:1:1. Also provided are compositions that include the supplement, such as a food product. The disclosure also includes, but is not limited to, methods for using the supplements, including improving the performance of an animal, improving a processing factor of an animal, or increasing intestinal health of an animal, where the method includes administering to the animal a food product that has the supplement.

IPC Classes  ?

• A23K 20/142 - Amino acidsDerivatives thereof
• A23K 20/184 - Hormones
• A23K 50/30 - Feeding-stuffs specially adapted for particular animals for swine
• A23K 50/60 - Feeding-stuffs specially adapted for particular animals for weanlings
• A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
• A23L 33/17 - Amino acids, peptides or proteins
• A23L 33/175 - Amino acids
• A23L 33/195 - Proteins from microorganisms
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 38/30 - Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Goods & Services

Animal feed supplements

Goods & Services

Animal feed supplements; nutritional supplements for animal consumption.

Goods & Services

Animal feed supplements; Nutritional supplements for animal consumption

Abstract

Provided herein are methods for treating an animal using a composition that includes active IGF. The methods include treating an animal at risk of having an infection caused by an infectious agent, treating an animal having an infection, and treating a symptom associated with an infection. In one embodiment, the infectious agent is a virus. In one embodiment, the administering includes daily administration of at least 0.05 nanograms of active IGF-1 per kilogram bodyweight of the animal daily (ng/kg), at least 0.1 ng/kg, at least 2 ng/kg, at least 5 ng/kg, or at least 10 ng/kg.

IPC Classes  ?

• A61K 38/30 - Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
• A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
• A61K 9/00 - Medicinal preparations characterised by special physical form

Goods & Services

Nutritional supplements for human and animal consumption.

Goods & Services

Nutritional supplements for human and animal consumption.

Goods & Services

Nutritional supplements for human and animal consumption.

Abstract

Provided herein are methods for altering a characteristic of an offspring or a litter. The method can include administering an effective amount of a composition that includes active IGF-1 to a pregnant animal, wherein a characteristic of an offspring of the pregnant animal is altered compared to a control offspring. In another embodiment, the animal is a lactating animal, wherein a characteristic of an offspring nursed by the lactating animal is altered compared to a control offspring. Examples of characteristics that can be altered include increased survival of offspring before weaning, increased weight of offspring at weaning, increased weight of offspring at end of growing phase, increased average daily gain, and increased average daily food intake. In another embodiment, a characteristic of a litter can be altered, such as increased number of offspring born alive, increased litter birth weight, increased offspring birth weight, reduced number of stillborn offspring, or a combination thereof.

IPC Classes  ?

• A61K 38/30 - Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Abstract

Provided wherein are methods for treating inflammation. In one embodiment, the method includes administering an effective amount of a composition to a subject having or at risk of having a condition that includes inflammation. The condition can be arthritis, tendonitis, osteoarthritis, fibrosis, shingles, psoriasis, acne, or dermatitis. Examples of dermatitis include atopic dermatitis, contact dermatitis, and seborrhoeic dermatitis. In one embodiment, the method includes administering an effective amount of a composition to a subject having pain, heat, and/or redness associated with inflammation. In one embodiment, the composition administered can include active TGF-β at a concentration of at least 0.001 nanograms/gram (ng/g). Optionally, the active TGF-β can be at a concentration of no greater than 4000 ng/g.

IPC Classes  ?

• A61K 38/18 - Growth factorsGrowth regulators

Abstract

Provided herein are methods for increasing the concentration of insulin-like growth factor (IGF) in the serum of a subject. In one embodiment, the method includes administering active IGF-1 to a subject, wherein the concentration of IGF in the serum of the subject is increased. Also provided are methods for treating a condition in a subject, methods for improving or maintaining the health of a subject, and methods for improving a characteristic of a subject. Examples of conditions include a motor neuron disorder, Alzheimer's disease, myocardial infarction, hypoxic-ischemic brain injury, osteoporosis, skeletal muscle repair, and growth failure. Examples of characteristics include increased milk production, increased fertilization, increased reproduction, increased growth, increased oocyte quality in a ruminant undergoing superovulation, and increased embryo viability. In one embodiment, the IGF-1 administered to the subject is obtained from a natural source that has been processed to increase the amount of active IGF-1.

IPC Classes  ?

• A61K 38/30 - Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum

Goods & Services

Nutritional supplements for human and animal consumption

Abstract

Provided herein are methods for treating an animal using a composition that includes active IGF. The methods include treating an animal at risk of having an infection caused by an infectious agent, treating an animal having an infection, and treating a symptom associated with an infection. In one embodiment, the infectious agent is a virus. In one embodiment, the administering includes daily administration of at least 0.05 nanograms of active IGF-1 per kilogram bodyweight of the animal daily (ng/kg), at least 0.1 ng/kg, at least 2 ng/kg, at least 5 ng/kg, or at least 10 ng/kg.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides

Abstract

A feeding composition including activated growth factor(s) increases feed to gain ratio, increases overall weight gain, reduces necessary antibiotic or electrolyte therapy and reduces mortality in animals. The composition is derived by first separating growth factor(s) from a source such as whey or blood, then subjecting the factor to an activation process, and then providing the activated growth factor to the animal. A feed additive comprising activated growth factors in appropriate amounts, shows results that are an improvement over standard therapies of supplementation. Application of activated growth factors may be by topical, injection or oral application.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides

Goods & Services

Animal feed supplements