Abstract

Monoclonal antibodies and antibody fragments that selectively bind to invariant region 4 or 6 (IR4, IR6) of a VlsE (variable major protein-like sequence, expressed) protein. The VlsE protein is found on the surface of multiple variants of spirochete bacteria that cause Lyme disease. The protein is abundantly and continuously expressed throughout the bacteria's time in its vertebrate host and thus detection over the entire infection is enabled. A label may be attached to enable imaging of the bacteria.

IPC Classes  ?

• C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Abstract

A method for treating a fluid is provided. Particles are coated with quaternary ammonium or phosphonium compounds (“quats”). Fluid is passed over the particles. The biocidal properties of the quats treats the fluid.

IPC Classes  ?

• C09D 5/16 - Anti-fouling paintsUnderwater paints
• C09D 7/20 - Diluents or solvents

Abstract

Tripeptides (sequence isomers of K/Y/W) and a method for using the same. The tripeptides, upon a process of evaporation-driven self-assembly, undergo two-stage phase separation to form highly porous particles upon drying. These particles readily re-dissolved upon reintroduction of water. The particles can trap molecular payloads that can be readily released in aqueous media.

IPC Classes  ?

• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61L 27/52 - Hydrogels or hydrocolloids
• C07K 5/08 - Tripeptides

Abstract

A method for deriving topics from known textual sources to apply those models to unknown textual sources comprises accepting a first input from a first data source that has data related to at least one specified subject, thereby producing a first accepted input; grouping the accepted first input into first groups using a language model; labeling the first groups with identifiers; receiving a second input from a second data source; searching the accepted second input using a language model, thereby producing searched second input; identifying a first group for at least some of the searched second input; and creating at least one new group for any searched second input that was not identified with a first group.

IPC Classes  ?

• G06F 16/24 - Querying
• G06N 20/00 - Machine learning

Abstract

The invention relates to methods of diagnosing and/or treating a subject having, or being at risk of developing, a disease or condition that is associated with amyloidosis.

Abstract

Methods and systems for treating spasticity, hypertonia or dystonia are disclosed.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
• A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
• A61N 1/20 - Applying electric currents by contact electrodes continuous direct currents
• A61N 1/24 - Electromedical belts with built-in power source
• A61P 25/14 - Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Abstract

Optical systems include a first optical element featuring a first substrate, a partially-reflective coating disposed on a first surface of the first substrate, a first meta-material layer positioned on or adjacent to a first surface of the first substrate and including a structure that defines a continuous phase gradient along a first direction parallel to the first surface of the first substrate, and a second optical element featuring a second substrate and a second meta-material layer positioned on or adjacent to a first surface of the second substrate and comprising a structure that defines a continuous phase gradient along a second direction parallel to the first surface of the first substrate, where at least one surface of the second optical element is curved along the second direction.

IPC Classes  ?

• G02B 5/30 - Polarising elements
• G01B 9/02 - Interferometers
• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements

Abstract

Optical systems include a first optical element featuring a first substrate, a partially-reflective coating disposed on a first surface of the first substrate, a first meta-material layer positioned on or adjacent to a first surface of the first substrate and including a structure that defines a continuous phase gradient along a first direction parallel to the first surface of the first substrate, and a second optical element featuring a second substrate and a second meta-material layer positioned on or adjacent to a first surface of the second substrate and comprising a structure that defines a continuous phase gradient along a second direction parallel to the first surface of the first substrate, where at least one surface of the second optical element is curved along the second direction.

IPC Classes  ?

• G01J 3/14 - Generating the spectrumMonochromators using refracting elements, e.g. prism
• G01J 3/45 - Interferometric spectrometry
• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements

Abstract

Optical systems include a first optical element featuring a first substrate, a partially-reflective coating disposed on a first surface of the first substrate, a first meta-material layer positioned on or adjacent to a first surface of the first substrate and including a structure that defines a continuous phase gradient along a first direction parallel to the first surface of the first substrate, and a second optical element featuring a second substrate and a second meta-material layer positioned on or adjacent to a first surface of the second substrate and comprising a structure that defines a continuous phase gradient along a second direction parallel to the first surface of the first substrate, where at least one surface of the second optical element is curved along the second direction.

IPC Classes  ?

• G01J 3/12 - Generating the spectrumMonochromators
• G01J 3/26 - Generating the spectrumMonochromators using multiple reflection, e.g. Fabry-Perot interferometer, variable interference filter
• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
• G02B 5/28 - Interference filters

Abstract

Optical elements include a substrate, a partially-reflective coating disposed on a first surface of the substrate, a meta-material layer positioned on or adjacent to a first surface of the substrate and featuring a structure that defines a continuous phase gradient along a first direction parallel to the first surface of the substrate, where a change in magnitude of the phase along the first direction is at least 2Ξ at a wavelength Σ, and a partially-reflective layer disposed on or adjacent to the meta-material layer and on an opposite side of the meta-material layer from the substrate.

IPC Classes  ?

• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
• G02B 1/115 - Multilayers
• G02B 5/08 - Mirrors

Abstract

Optical elements include a substrate, a partially-reflective coating disposed on a first surface of the substrate, a meta-material layer positioned on or adjacent to a first surface of the substrate and featuring a structure that defines a continuous phase gradient along a first direction parallel to the first surface of the substrate, where a change in magnitude of the phase along the first direction is at least 2X at a wavelength S, and a partially-reflective layer disposed on or adjacent to the meta-material layer and on an opposite side of the meta-material layer from the substrate.

IPC Classes  ?

• G01J 3/12 - Generating the spectrumMonochromators
• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements

Abstract

Optical systems include a first optical element featuring a first substrate, a partially-reflective coating disposed on a first surface of the first substrate, a first meta-material layer positioned on or adjacent to a first surface of the first substrate and including a structure that defines a continuous phase gradient along a first direction parallel to the first surface of the first substrate, and a second optical element featuring a second substrate and a second meta-material layer positioned on or adjacent to a first surface of the second substrate and comprising a structure that defines a continuous phase gradient along a second direction parallel to the first surface of the first substrate, where at least one surface of the second optical element is curved along the second direction.

IPC Classes  ?

• G01J 3/12 - Generating the spectrumMonochromators
• G01J 3/26 - Generating the spectrumMonochromators using multiple reflection, e.g. Fabry-Perot interferometer, variable interference filter
• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
• G02B 5/28 - Interference filters

Abstract

Specifically, the invention relates to compositions and methods for treating liver ailments, such as compositions and methods for attenuating or ameliorating the development of alcoholic liver disease (ALD), hepatic steatosis, liver oxidative stress and/or hepatic lipogenesis associated with alcohol consumption in a subject by administering a retinoic acid receptor-beta (RARβ) agonist.

IPC Classes  ?

• A61K 31/426 - 1,3-Thiazoles
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Abstract

An energy facility that generates energy using ballistic optimized hydro-electricity. The facility sends a plurality of specialized balls from a lower storage reservoir to an upper storage reservoir. The balls fall through a drop-down system and into a power generation system with a generator and a turbine. Ballistic impacts of the balls on the turbine generate electricity before the balls are returned to the lower storage reservoir.

IPC Classes  ?

• H02K 7/18 - Structural association of electric generators with mechanical driving motors, e.g.with turbines

Abstract

An electro-optical converter that converts an electric signal to an optical signal. An optical signal is dragged from one optical channel to another optical channel using exciton polaritons that are generated in a layer that is adjacent the optical channels. The exciton polaritons are generated in response to an electrical signal which thereby results in the selective production of the optical signal.

IPC Classes  ?

• G02F 1/313 - Digital deflection devices in an optical waveguide structure

Abstract

The present disclosure provides, in part, methods for site-specific labeling of proteins/peptides with radiohalogens and compositions resulting from said methods.

IPC Classes  ?

• A61K 51/10 - Antibodies or immunoglobulinsFragments thereof
• C07B 59/00 - Introduction of isotopes of elements into organic compounds
• C07K 1/107 - General processes for the preparation of peptides by chemical modification of precursor peptides

Abstract

A synthetic mucin formed by performing a ring-opening polymerization of carbohydrate N-carboxyanhydride (NCA) followed by deprotection of at least one protecting group from the carbohydrate. The resulting synthetic mucin can be produced in large quantities and obviates many of the problems associated with using natural mucins obtained from biological sources.

IPC Classes  ?

• C08G 69/10 - Alpha-amino-carboxylic acids
• C08G 69/48 - Polymers modified by chemical after-treatment
• C08J 3/075 - Macromolecular gels
• C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules

Abstract

A nucleotide that encodes for a destabilized RNA that codes for ERBB2 (erythroblastic oncogene B) or MYC oncogenes. The destabilization occurs in an adenylate-uridylate rich element (ARE) stabilizing motif. Without wishing to be bound to any particular theory, changing the stabilizing motifs of ERBB2 and MYC to destabilization motifs is believed to lead to the rapid degradation of their transcripts. Thus, in turn, renders the composition useful as a therapeutic for cancer.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
• C12Q 1/6897 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
• A61P 35/00 - Antineoplastic agents
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

A method for producing customized object is provided. A resin (e.g. plastic or cellulose) is heated and a quaternary salt is added. The resulting admixture is used in forming a material that embodies customized characteristics. In another embodiment, a halogen-containing polymer has a quaternary molecule covalently bonded to it that results in customized properties.

IPC Classes  ?

• C08J 3/21 - Compounding polymers with additives, e.g. colouring in the presence of a liquid phase the polymer being premixed with a liquid phase
• C08K 3/32 - Phosphorus-containing compounds
• C08K 5/19 - Quaternary ammonium compounds

Abstract

A method comprising: receiving a hyperspectral image of a scene; selecting one or more bands from the hyperspectral image; and processing the selected bands to produce a color image, wherein processing the selected bands to produce a color image includes: generating an LMS image by performing an RGB-to-LMS conversion on the selected bands; replacing a V-channel of an HSV image with an enhanced L-channel of the LMS image to produce a resultant HSV image, the HSV image being an image of the same scene as the hyperspectral image; and performing an HSV-to-RGB conversion on the resultant HSV image produces the color image.

IPC Classes  ?

• G06T 11/00 - 2D [Two Dimensional] image generation
• G06T 5/40 - Image enhancement or restoration using histogram techniques
• G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
• G06T 5/60 - Image enhancement or restoration using machine learning, e.g. neural networks
• G06V 10/56 - Extraction of image or video features relating to colour
• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks

Abstract

222S-releasing moiety covalently bonded to an aspirin derived core, or combinations thereof; and a polar solvent, when the seeds are pre-germination. The seeds and a kit containing the compound(s) is also claimed.

IPC Classes  ?

• A01N 43/26 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with two or more hetero atoms five-membered rings
• A01P 21/00 - Plant growth regulators
• C07D 339/04 - Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Abstract

12mnnT1nT2222 is independently selected from F, Y and W; and m is an integer from 1 to 6; and n is 1 or zero. The peptide exhibits intrinsic fluorescence.

IPC Classes  ?

• C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• G01N 21/64 - FluorescencePhosphorescence
• C07K 1/32 - ExtractionSeparationPurification by precipitation as complexes
• C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
• G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light

Abstract

A device for generating singlet oxygen is provided. The device has a sensitizer that converts triplet oxygen to singlet oxygen upon exposure to light. The device is configured to keep the sensitizer from contacting external fluids.

IPC Classes  ?

• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 71/26 - Polyalkenes

Abstract

Methods and devices for generating high dimensional structured light are disclosed herein. In one aspect, a method can include: generating, via a first microring of a microlaser, a first structured light emission having a first degree of freedom and a second degree of freedom; and generating, via a second microring of a microlaser, a second structured light emission having a third degree of freedom and a fourth degree of freedom, wherein an interaction between the first structured light emission and the second structured light emission forms a fifth degree of freedom.

IPC Classes  ?

• G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for
• G02B 26/10 - Scanning systems
• H04B 10/532 - Polarisation modulation
• H04B 10/54 - Intensity modulation
• H04B 10/548 - Phase or frequency modulation

Abstract

A method for forming peptide-coated nanoparticles. The nanoparticles are polylactic co-glycol polymer (PLGA). The coatings are self-assembled layers selected from RGDFFF (SEQ ID NO: 1); NGRFFF (SEQ ID NO: 2), EKHFFF (SEQ ID NO: 3) or TPP-KFF. A cargo molecule, such as a dye or a therapeutic may be bound to the nanoparticle.

IPC Classes  ?

• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61K 9/51 - Nanocapsules
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids

Abstract

rrr-2. The net number of the aromatic residues is greater than or equal to the net number of positive residues.

IPC Classes  ?

• A61K 38/07 - Tetrapeptides
• A61K 38/08 - Peptides having 5 to 11 amino acids
• C07K 5/10 - Tetrapeptides
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids

Abstract

An apparatus comprises an antenna; and a matching circuit comprising at least one electronic circuit element including a dispersive material for tuning the antenna to modify a bandwidth of the antenna. The dispersive material is configured to nullify at least a portion of the stored energy of at least one electronic circuit element from a vantage point of an antenna port of the antenna.

IPC Classes  ?

• G21K 1/00 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
• H01Q 5/335 - Individual or coupled radiating elements, each element being fed in an unspecified way using frequency dependent circuits or components, e.g. trap circuits or capacitors at the feed, e.g. for impedance matching
• H01Q 7/00 - Loop antennas with a substantially uniform current distribution around the loop and having a directional radiation pattern in a plane perpendicular to the plane of the loop

Abstract

An apparatus comprises an antenna; and a matching circuit comprising at least one electronic circuit element including a dispersive material for tuning the antenna to modify a bandwidth of the antenna. The dispersive material is configured to nullify at least a portion of the stored energy of at least one electronic circuit element from a vantage point of an antenna port of the antenna.

IPC Classes  ?

• H01P 3/08 - MicrostripsStrip lines
• H01P 7/10 - Dielectric resonators
• H01Q 5/40 - Imbricated or interleaved structuresCombined or electromagnetically coupled arrangements, e.g. comprising two or more non-connected fed radiating elements
• H01Q 7/06 - Loop antennas with a substantially uniform current distribution around the loop and having a directional radiation pattern in a plane perpendicular to the plane of the loop with core of ferromagnetic material

Abstract

The present disclosure provides compounds, methods, and compositions which may be used to treat tuberculosis. In some embodiments, these compounds and compositions have a bactericidal property against Mycobacterium tuberculosis (Mtb). Methods of employing such agents are also provided.

IPC Classes  ?

• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61K 31/136 - Amines, e.g. amantadine having aromatic rings, e.g. methadone having the amino group directly attached to the aromatic ring, e.g. benzeneamine
• A61K 31/235 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A61K 31/402 - 1-aryl-substituted, e.g. piretanide
• A61K 31/426 - 1,3-Thiazoles
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 31/5375 - 1,4-Oxazines, e.g. morpholine
• A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/04 - Antibacterial agents
• A61P 31/06 - Antibacterial agents for tuberculosis

Abstract

A system for training a neural network includes a neural network configured to receive a training input in an image space and produce an enhanced image. The system further includes an error signal generator configured to compare the enhanced image to a ground truth and generate an error signal that is communicated back to the neural network to train the neural network. Additionally, the system includes a neural input enhancer configured to modify the training input in response to receiving at least one of an output from the neural network or the error signal. Modifying the training input improves one of an efficiency or a training result of the neural network beyond the communication of the error signal to only the neural network.

IPC Classes  ?

• G06V 10/776 - ValidationPerformance evaluation
• G06T 5/00 - Image enhancement or restoration
• G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
• G06V 10/60 - Extraction of image or video features relating to illumination properties, e.g. using a reflectance or lighting model
• G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
• G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks

Abstract

A biocompatible adhesive suitable for both internal and topical use. The adhesive is a tissue-adhesive hydrogel formed from an oxidized carboxymethylcellulose (oCMC) with aldehyde functional groups and a methacrylated methylcellulose (mMC).

IPC Classes  ?

• C08L 1/26 - Cellulose ethers
• C08B 11/02 - Alkyl or cycloalkyl ethers
• A61L 27/20 - Polysaccharides
• A61L 27/52 - Hydrogels or hydrocolloids
• C08B 15/04 - Carboxycellulose, e.g. prepared by oxidation with nitrogen dioxide

Abstract

The disclosure generally relates to the artificial intelligence (AI) automatic methods, computer program product, and systems and methodology for dietary and medical treatment planning, food waste estimation, analyzing three-dimensional food image construction, measurement, nutrient estimation, nutritional assessment, evaluation, prediction and management. More particularly, the embodiments described herein relate to utilizing an AI-based algorithm that can automatically, detect food items from images acquired by cameras for dietary assessment, dietary planning, and for estimating food waste. In one aspect, the method may include food calorie estimation techniques using machine learning and computer vision techniques for dietary assessment. In another aspect, the tools may apply to personalized nutrition. The method may also include the automation of nutrition planning. In yet another aspect, the tools may apply to medical treatment planning, wherein meals and treatment plans are individualized explicitly for each user according to several unique characteristics associated with that user.

IPC Classes  ?

• G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
• G06N 3/0464 - Convolutional networks [CNN, ConvNet]
• G06N 3/08 - Learning methods
• G06N 20/10 - Machine learning using kernel methods, e.g. support vector machines [SVM]

Abstract

A method comprising: obtaining a plurality of data sets, each of the plurality of data sets being generated, at least in part, by using by a different one of a plurality of sensors, each of a plurality of sensors including a wearable sensor that is worn by a user or a sensor that is positioned at a same location as the user; combining the plurality of data sets to produce a fused data set; processing the fused data set to identify at least one of a performance of the user in completing a task, a cognitive load of the user, and/or one or more objects that are positioned at the same location as the user; and outputting an indication of a state of the user based on an outcome of the processing.

IPC Classes  ?

• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
• G06V 40/18 - Eye characteristics, e.g. of the iris
• G06T 7/70 - Determining position or orientation of objects or cameras

Abstract

Disclosed herein is a microcavity comprising a photoluminescent material positioned between two reflectors, wherein the photoluminescent material comprises a cationic molecular dye, a macrocyclic anion receptor host, and an anion embedded within the macrocyclic anion receptor host and methods of making and using the same.

IPC Classes  ?

• C07C 255/49 - Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
• C07C 255/58 - Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
• C07D 209/56 - Ring systems containing three or more rings
• H10K 85/60 - Organic compounds having low molecular weight
• H10K 50/11 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers

Abstract

Methods and systems for spinal cord stimulation (SCS) are disclosed. The methods and systems involve using electrode leads implanted within the patient's spinal column to record neural responses evoked by the stimulation. The disclosed neural responses are different in several respects from electrical responses that have previously been measured in the context of SCS, such as stimulation artifacts and evoked compound action potentials (ECAPs). The disclosed neural responses typically occur later in time following the evoking stimulation pulse. Another distinguishing feature is that disclosed neural responses are generally most prominently observed with consistent, relatively unchanging amplitudes when the evoking stimulation frequency is ultra-low, for example, about 10 Hz or less. The disclosed methods and systems may use these neural responses as indications of pain, therapy, and/or another clinically relevant dimension, to direct/confirm stimulation placement, and for feedback control of stimulation parameters.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

Abstract

Methods and systems for spinal cord stimulation (SCS) are disclosed. The methods and systems involve using electrode leads implanted within the patient's spinal column to record neural responses evoked by the stimulation. The disclosed neural responses are different in several respects from electrical responses that have previously been measured in the context of SCS, such as stimulation artifacts and evoked compound action potentials (ECAPs). The disclosed neural responses typically occur later in time following the evoking stimulation pulse. Another distinguishing feature is that disclosed neural responses are generally most prominently observed with consistent, relatively unchanging amplitudes when the evoking stimulation frequency is ultra-low, for example, about 10 Hz or less. The disclosed methods and systems may use these neural responses as indications of pain, therapy, and/or another clinically relevant dimension, to direct/confirm stimulation placement, and for feedback control of stimulation parameters.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

Abstract

A thermal desalination system connected to a heat source, such as a power plant that generates waste heat, that produces a heated liquid. The heated liquid is routed to a heat exchanger and/or a desalination device before being returned to the heat source. When present, the heat exchanger preheats water for subsequent purification by distillation, thereby producing potable water.

IPC Classes  ?

• C02F 1/04 - Treatment of water, waste water, or sewage by heating by distillation or evaporation
• C02F 1/16 - Treatment of water, waste water, or sewage by heating by distillation or evaporation using waste heat from other processes
• B01D 1/00 - Evaporating

Abstract

A device for performing unitary matrix computations comprises a light source configured to generate first optical signals; an array of waveguides, including: inputs that receive the first optical signals from the light source; a plurality of channels positioned in parallel for transmitting the first optical signals along a length of the waveguides; and outputs for outputting second optical signals generated according to a matrix multiplication operation from the first optical signals. The device further comprises phase shifters constructed and arranged in a cascade structure at the channels of the waveguides, the waveguides include sections or directional couplers between adjacent phase shifter. The matrix multiplication operation includes coupling coefficient values between adjacent waveguides and length values of the sections of the waveguides. General non-unitary matrix computations are implemented by interlacing two embodiments of the device together with an array of amplitude modulators.

IPC Classes  ?

• G02B 6/12 - Light guidesStructural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind

Abstract

A method for concentrating a liquid sample containing pathogens. The method traps pathogens on the surface of activated carbon. Prior to release of the pathogens, the activated carbon is treated with a blocking solution that prevents the activated carbon from degrading and/or binding the released pathogen nucleic acids. After treatment with the blocking solution, the pathogens are released from the activated carbon with a lysis reagent.

IPC Classes  ?

• C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor

Abstract

A system for utilizing zinc oxide includes a first electrode comprising a zinc oxide reagent material, a current collector electrically connected to the zinc oxide reagent material, and a second electrode. The zinc oxide reagent material is capable of electrochemical intercalation and de-intercalation reactions with an electrolyte, and the zinc oxide reagent material comprises a zinc oxide intercalated with electrons. The current collector is configured to provide electrons and voltage control to the zinc oxide reagent material. The electrolyte in contact with the zinc oxide reagent material and is capable of executing intercalation reactions with the zinc oxide reagent material. The electronics are configured to control electrochemical voltage of the current collector and the zinc oxide reagent material, and the second electrode comprises a counter-electrode or a reference electrode electrically coupled to one or more electronics.

IPC Classes  ?

• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• H01M 4/24 - Electrodes for alkaline accumulators
• H01G 11/46 - Metal oxides
• H01G 11/28 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features arranged or disposed on a current collectorLayers or phases between electrodes and current collectors, e.g. adhesives
• C01G 9/02 - OxidesHydroxides

Abstract

Described herein are methods for producing enriched populations of progenitor rod photoreceptor cells (PRPs) and EVs derived therefrom, as well as methods of using the PRPs and EVs to diagnose and treat retinal disease.

IPC Classes  ?

• A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
• A61P 27/02 - Ophthalmic agents
• C12N 5/0797 - Stem cellsProgenitor cells

Abstract

A nucleotide that encodes for a destabilized RNA that corresponds to ERBB2 (erythroblastic oncogene B) or MYC oncogenes. The destabilization occurs in an adenylate-uridylate rich element (ARE) stabilizing motif. Without wishing to be bound to any particular theory, changing the stabilizing motifs of ERBB2 and MYC to destabilization motifs is believed to lead to the rapid degradation of their transcripts. Thus, in turn, renders the composition useful as a therapeutic for cancer.

IPC Classes  ?

• C07K 14/82 - Translation products from oncogenes
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

A predictive method that uses satellite-based nighttime light (NTL) observations as a proxy for power outage data that occurred during a hurricane. The NTL data is provided to a machine learning module along with exploratory variables. The module forecasts hurricane-induced power loss based on the NTL and exploratory variables. The method does not require any data from the utility, making it useful for isolated regions or regions with limited power outage records.

IPC Classes  ?

• G06Q 10/0631 - Resource planning, allocation, distributing or scheduling for enterprises or organisations
• G06Q 10/04 - Forecasting or optimisation specially adapted for administrative or management purposes, e.g. linear programming or "cutting stock problem"
• G06Q 50/06 - Energy or water supply
• G06N 20/00 - Machine learning

Abstract

Methods, apparatus and program products for acquiring and analyzing images of a sample. An artificial intelligence (AI) module may be trained to identify, within multi-dimensional image data corresponding to images of objects, wavelength patterns corresponding to one or more defects within the objects. An analysis module is configured to detect one or more defects in the sample using the AI module for analyzing the images of the sample. In some embodiments, the samples are food samples and the defects include one or more pathogens.

IPC Classes  ?

• G06T 7/246 - Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
• G06F 18/24 - Classification techniques
• G06V 20/68 - Food, e.g. fruit or vegetables

Abstract

Specifically, the invention relates to compositions and methods for treating liver ailments, such as compositions and methods for attenuating or ameliorating the development of alcoholic liver disease (ALD), hepatic steatosis, liver oxidative stress and/or hepatic lipogenesis associated with alcohol consumption in a subject by administering a retinoic acid receptor-beta (RARβ) agonist.

IPC Classes  ?

• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 31/426 - 1,3-Thiazoles
• A61P 3/06 - Antihyperlipidemics

Abstract

A method for detecting an airborne object. Electromagnetic radiation is emitted from a transmitter to overlap with a receiver's field of view. When an airborne object enters the field of view, the electromagnetic radiation interacts with moving airfoils on the airborne object to produce reflected and scattered electromagnetic radiation. The reflected and scattered electromagnetic radiation is analyzed to detect, classify and/or determine the orientation of the airborne object.

IPC Classes  ?

• G01S 17/88 - Lidar systems, specially adapted for specific applications
• G01S 7/481 - Constructional features, e.g. arrangements of optical elements

Abstract

The present disclosure provides, in part, methods for site-specific labeling of proteins/peptides with radiohalogens and compositions resulting from said methods.

IPC Classes  ?

• A61K 51/08 - Peptides, e.g. proteins
• A61K 51/10 - Antibodies or immunoglobulinsFragments thereof
• C07D 271/113 - 1,3,4-OxadiazolesHydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
• C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07K 5/02 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof containing at least one abnormal peptide link
• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• C12Q 1/16 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor using radioactive material

Abstract

A device for storage and transport of biological samples. Multiple trays are assembled into a stack with sample tubes constrained between adjacent trays. The surface of each tray has radial grooves sized to hold the sample tubes. Each tray is secured to an adjacent tray with a bolt or snap-fit connector.

IPC Classes  ?

• B01L 9/06 - Test-tube standsTest-tube holders

Abstract

A method and composite for treating a wound. A wound is sprayed with a composition that includes a volatile organic solvent, a biocompatible polymer and turmeric powder. The solvent evaporates during the spraying. The resulting composite stops bleeding instantly, can remain on the wound for prolonged periods and adheres with the wound, even under arterial pressure. The composite serves to promote wound healing and hemostasis in bleeding wounds.

IPC Classes  ?

• A61L 26/00 - Chemical aspects of, or use of materials for, liquid bandages
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

The present disclosure provides, in part, methods for site-specific labeling of proteins/peptides with radiohalogens and compositions resulting from said methods.

IPC Classes  ?

• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• C07D 271/113 - 1,3,4-OxadiazolesHydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
• A61K 51/04 - Organic compounds
• A61K 51/10 - Antibodies or immunoglobulinsFragments thereof

Abstract

A synthetic mucin formed by performing a ring-opening polymerization of carbohydrate N-carboxyanhydride (NCA) followed by deprotection of at least one protecting group from the carbohydrate. The resulting synthetic mucin can be produced in large quantities and obviates many of the problems associated with using natural mucins obtained from biological sources.

IPC Classes  ?

• C08G 69/16 - Preparatory processes
• C08G 69/10 - Alpha-amino-carboxylic acids

Abstract

A battery comprises a housing, an electrolyte disposed in the housing, a cathode disposed in the housing, an anode disposed in the housing and comprising an anode material comprising: zinc or zinc oxide, an electrocoagulant material selected from the group consisting of: aluminum, iron, titanium, calcium, zirconium, a hydroxide thereof, a salt thereof, an oxide thereof, and a combination thereof, and a binder.

IPC Classes  ?

• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/24 - Electrodes for alkaline accumulators

Abstract

A method for redacting a private blockchain comprises applying a hash function to a prefix and new content to compute a hash for a block of the blockchain; performing a modulo operation to convert the hash to an integer modulo; determining an inverse of the integer modulo; computing a redactable suffix from the prefix and the inverse of the integer modulo; replacing current content of the blockchain with the new content; and applying the redactable suffix to the block having the new content.

IPC Classes  ?

• H04L 9/06 - Arrangements for secret or secure communicationsNetwork security protocols the encryption apparatus using shift registers or memories for blockwise coding, e.g. D.E.S. systems
• H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols
• H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system

Abstract

An energy facility that generates energy using ballistic optimized hydro-electricity. The facility sends a plurality of specialized balls from a lower storage reservoir to an upper storage reservoir. The balls fall through a drop-down system and into a power generation system with a generator and a turbine. Ballistic impacts of the balls on the turbine generate electricity before the balls are returned to the lower storage reservoir.

IPC Classes  ?

• H02K 7/18 - Structural association of electric generators with mechanical driving motors, e.g.with turbines

Abstract

A method comprising: receiving a hyperspectral image of a scene; selecting one or more bands from the hyperspectral image; and processing the selected bands to produce a color image, wherein processing the selected bands to produce a color image includes: generating an LMS image by performing an RGB-to-LMS conversion on the selected bands; replacing a V-channel of an HSV image with an enhanced L-channel of the LMS image to produce a resultant HSV image, the HSV image being an image of the same scene as the hyperspectral image; and performing an HSV-to-RGB conversion on the resultant HSV image produces the color image.

IPC Classes  ?

• G06T 9/00 - Image coding

Abstract

A thermal metasurface that provides a planar optical source based on thermal radiation or photoluminescence. The thermal metasurface provides dual perturbative control of both radiative and non-radiative lifetimes of a q-BIC via geometric and material perturbation of monomeric and dimeric pillars.

IPC Classes  ?

• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
• G02B 5/30 - Polarising elements

Abstract

Methods and systems for treating ALS and related motor neuron diseases using multi-site neuromodulation are disclosed.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
• A61N 1/18 - Applying electric currents by contact electrodes
• A61N 1/20 - Applying electric currents by contact electrodes continuous direct currents

Abstract

A battery includes a housing, an electrolyte disposed in the housing, an anode disposed in the housing, and an electrode disposed in the housing and comprising an electrode material comprising manganese dioxide, and a conductive carbon coated with a metallic layer. The use of the conductive carbon coated with the metallic layer can help to control the effects of other ions such as zincate on the manganese dioxide during discharge or cycling of the battery.

IPC Classes  ?

• H01M 10/26 - Selection of materials as electrolytes
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/04 - Processes of manufacture in general
• H01M 4/583 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/66 - Selection of materials
• H01M 4/74 - Meshes or woven materialExpanded metal

Abstract

A system and method for forming a metallic ion intercalated layered structure can include a housing, an electrolyte disposed in the housing, a counter-electrode disposed in the housing, and a working electrode disposed in the housing. The working electrode comprises a metallic support; and an electrode paste. The electrode paste can include an active material and a binder. The system can be used to form a layered structure having metallic ions from the metallic support intercalated into the layered structure based on cycling the working electrode.

IPC Classes  ?

• H01M 4/04 - Processes of manufacture in general
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 4/52 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron
• H01M 4/66 - Selection of materials

Abstract

A heating system for use in the solar powered heating of water. In one embodiment, the heating system is used in conjunction with a solar water farm to desalinate water. The water farm can be utilized on a variety of scales and can be applied to agricultural farms for large scale reclamation of deserts.

IPC Classes  ?

• C02F 1/14 - Treatment of water, waste water, or sewage by heating by distillation or evaporation using solar energy
• C02F 1/04 - Treatment of water, waste water, or sewage by heating by distillation or evaporation

Abstract

A method for Parametric resynthesis (PR) producing an audible signal. A degraded audio signal is received which includes a distorted target audio signal. A prediction model predicts parameters of the audible signal from the degraded signal. The prediction model was trained to minimize a loss function between the target audio signal and the predicted audible signal. The predicted parameters are provided to a waveform generator which synthesizes the audible signal.

IPC Classes  ?

• G10L 21/02 - Speech enhancement, e.g. noise reduction or echo cancellation
• G10L 13/047 - Architecture of speech synthesisers
• G10L 21/0264 - Noise filtering characterised by the type of parameter measurement, e.g. correlation techniques, zero crossing techniques or predictive techniques
• G10L 25/18 - Speech or voice analysis techniques not restricted to a single one of groups characterised by the type of extracted parameters the extracted parameters being spectral information of each sub-band
• G10L 25/30 - Speech or voice analysis techniques not restricted to a single one of groups characterised by the analysis technique using neural networks

Abstract

The present disclosure provides inhibitors of microorganisms including viruses and fungi of the formula (I) or (II) wherein the variables are defined herein. Also provided are methods of treatment using these agents in the treatment of infections of microorganisms such as viruses and fungi. The present disclosure provides inhibitors of microorganisms including viruses and fungi of the formula (I) or (II) wherein the variables are defined herein. Also provided are methods of treatment using these agents in the treatment of infections of microorganisms such as viruses and fungi.

IPC Classes  ?

• C07D 229/02 - Heterocyclic compounds containing rings of less than five members having two nitrogen atoms as the only ring hetero atoms containing three-membered rings
• C07C 233/58 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
• C07D 295/185 - Radicals derived from carboxylic acids from aliphatic carboxylic acids
• C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
• C07D 277/22 - Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
• C07C 233/63 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
• C07D 209/20 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
• C07D 307/68 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
• C07D 333/20 - Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
• C07D 413/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 211/26 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
• C07C 233/60 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
• C07D 317/28 - Radicals substituted by nitrogen atoms
• C07C 271/22 - Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
• C07C 311/18 - Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
• C07D 319/20 - 1,4-DioxanesHydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
• C07D 333/34 - Sulfur atoms
• C07D 271/12 - Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
• C07D 239/42 - One nitrogen atom
• C07C 317/24 - SulfonesSulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
• A61P 31/12 - Antivirals

Abstract

A malicious process detection system comprises a Virtual Machine Introspection (VMI) module that performs an introspection operation on at least one virtual machine; and an Intrusion Detection System (IDS) that communicates with the VW module to generate data that is analyzed by the IDS using a negative selection algorithm (NSA) and that identifies suspicious processes at the VM based on the analyzed data.

IPC Classes  ?

• G06F 21/53 - Monitoring users, programs or devices to maintain the integrity of platforms, e.g. of processors, firmware or operating systems during program execution, e.g. stack integrity, buffer overflow or preventing unwanted data erasure by executing in a restricted environment, e.g. sandbox or secure virtual machine
• G06F 21/55 - Detecting local intrusion or implementing counter-measures
• G06K 9/62 - Methods or arrangements for recognition using electronic means

Abstract

An indoor navigation system comprises a modeling subsystem that processes multimodal data regarding a location, individually generates a model of each of a plurality of overlapping local regions subdivided from the location, and maps the model of each region and a coordinate system of the model aligned with a floor plan of the location, and a navigation subsystem that processes the model to plot a path at the location for navigating a user along the path in real-time.

IPC Classes  ?

• H04W 4/33 - Services specially adapted for particular environments, situations or purposes for indoor environments, e.g. buildings
• H04W 4/029 - Location-based management or tracking services
• G01C 21/20 - Instruments for performing navigational calculations
• H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication

Abstract

A high voltage aqueous battery includes a cathode comprising a cathode electroactive material, an anode comprising an anode electroactive material, a catholyte solution in contact with the cathode, and a polymerized anolyte solution in contact with the anode. The catholyte solution can be polymerized, and an optional separator can be used between the anolyte and the catholyte.

IPC Classes  ?

• H01M 4/46 - Alloys based on magnesium or aluminium
• H01M 10/26 - Selection of materials as electrolytes
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/66 - Selection of materials

Abstract

P. putida host populations (H-I and H-II) are engineered. H-1 undergoes fluorescence when a nitrotoluene is detected but it is also engineered to metabolize nitrotoluenes to toluene as its sole nitrogen-source. H-I is 1-ACC Deaminase inactive and is further engineered to efflux toluene and provide toluene to adjacent H-II. In H-II, ACC is the N-source and metabolizes toluene as the sole carbon and energy source available. The H-II cells are engineered to not be able to use medium fructose. The H-II population has a promoter/GFP construct with a promoter sensitive to toluene and thus they fluoresce from that first nitrotoluene metabolite i.e. toluene, produced by the H-I cells. This is achieved by making H-II cells mutants unable to transport and phosphorylate fructose i.e. PTSFRU gene knock-out.

IPC Classes  ?

• C12N 9/78 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
• C12N 9/06 - Oxidoreductases (1.), e.g. luciferase acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
• C12N 1/20 - BacteriaCulture media therefor
• C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
• C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• C12N 15/62 - DNA sequences coding for fusion proteins
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 15/78 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions

Abstract

x) that is orthogonal thereto. Each nanofeature is tailored to scatter with different patterns one polarization state of electromagnetic radiation and one orthogonal polarization state of electromagnetic radiation.

IPC Classes  ?

• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
• G02B 27/10 - Beam splitting or combining systems

Abstract

A method comprising: obtaining a plurality of data sets, each of the plurality of data sets being generated, at least in part, by using by a different one of a plurality of sensors, each of a plurality of sensors including a wearable sensor that is worn by a user or a sensor that is positioned at a same location as the user; combining the plurality of data sets to produce a fused data set; processing the fused data set to identify at least one of a performance of the user in completing a task, a cognitive load of the user, and/or one or more objects that are positioned at the same location as the user; and outputting an indication of a state of the user based on an outcome of the processing.

IPC Classes  ?

• G06N 3/02 - Neural networks
• G06N 3/04 - Architecture, e.g. interconnection topology
• G06N 3/08 - Learning methods
• G06N 5/04 - Inference or reasoning models
• G06T 7/00 - Image analysis
• G06T 7/10 - SegmentationEdge detection

Abstract

A system for utilizing zinc oxide includes a first electrode comprising a zinc oxide reagent material, a current collector electrically connected to the zinc oxide reagent material, and a second electrode. The zinc oxide reagent material is capable of electrochemical intercalation and de-intercalation reactions with an electrolyte, and the zinc oxide reagent material comprises a zinc oxide intercalated with electrons. The current collector is configured to provide electrons and voltage control to the zinc oxide reagent material. The electrolyte in contact with the zinc oxide reagent material and is capable of executing intercalation reactions with the zinc oxide reagent material. The electronics are configured to control electrochemical voltage of the current collector and the zinc oxide reagent material, and the second electrode comprises a counter-electrode or a reference electrode electrically coupled to one or more electronics.

IPC Classes  ?

• H01M 4/42 - Alloys based on zinc
• H01M 4/04 - Processes of manufacture in general
• H01M 4/24 - Electrodes for alkaline accumulators
• H01M 4/26 - Processes of manufacture
• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides

Abstract

The disclosure generally relates to the artificial intelligence (AI) automatic methods, computer program product, and systems and methodology for dietary and medical treatment planning, food waste estimation, analyzing three-dimensional food image construction, measurement, nutrient estimation, nutritional assessment, evaluation, prediction and management. More particularly, the embodiments described herein relate to utilizing an AI-based algorithm that can automatically, detect food items from images acquired by cameras for dietary assessment, dietary planning, and for estimating food waste. In one aspect, the method may include food calorie estimation techniques using machine learning and computer vision techniques for dietary assessment. In another aspect, the tools may apply to personalized nutrition. The method may also include the automation of nutrition planning. In yet another aspect, the tools may apply to medical treatment planning, wherein meals and treatment plans are individualized explicitly for each user according to several unique characteristics associated with that user.

IPC Classes  ?

• G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
• G06N 20/00 - Machine learning
• G06Q 30/00 - Commerce
• G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance

Abstract

A system for training a neural network includes a neural network configured to receive a training input in an image space and produce an enhanced image. The system further includes an error signal generator configured to compare the enhanced image to a ground truth and generate an error signal that is communicated back to the neural network to train the neural network. Additionally, the system includes a neural input enhancer configured to modify the training input in response to receiving at least one of an output from the neural network or the error signal. Modifying the training input improves one of an efficiency or a training result of the neural network beyond the communication of the error signal to only the neural network.

IPC Classes  ?

• G06K 9/62 - Methods or arrangements for recognition using electronic means

Abstract

Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts or tautomers thereof. Also provided are pharmaceutical compositions, kits, and methods involving the inventive compounds for the treatment and/or prevention of an infectious disease (e.g., bacterial infection (e.g., Mycobacterium infection (e.g., tuberculosis)). (I) Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts or tautomers thereof. Also provided are pharmaceutical compositions, kits, and methods involving the inventive compounds for the treatment and/or prevention of an infectious disease (e.g., bacterial infection (e.g., Mycobacterium infection (e.g., tuberculosis)). (I)

IPC Classes  ?

• C07D 473/30 - Oxygen atom attached in position 6, e.g. hypoxanthine
• C07D 473/18 - Heterocyclic compounds containing purine ring systems with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Abstract

Fabry disease is a rare (incidence approximately 1 in 20,000) X-linked inborn error of glycolipid metabolism caused by a deficiency of the lysosomal enzyme, α-galactosidase A, that leads to early death in affected males due to occlusive disease of the heart, kidney, and brain. The present invention provides a method to treat Fabry disease with a modified alpha-Galactosidase A enzyme derivative with improved stability and catalytic properties. As a result of the present invention, an effective therapeutic effect is achieved with a lower dose of enzyme infused to the patients.

IPC Classes  ?

• C12N 9/40 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase

Abstract

A heating system for use in the solar powered heating of water. The heating system is used in conjunction with a solar water farm to desalinate water. The water farm can be utilized on a variety of scales and can be applied to agricultural farms for large scale reclamation of deserts.

IPC Classes  ?

• C02F 1/14 - Treatment of water, waste water, or sewage by heating by distillation or evaporation using solar energy
• B01D 3/02 - Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping in boilers or stills
• B01D 1/00 - Evaporating
• C02F 103/08 - Seawater, e.g. for desalination

Abstract

A method for producing customized object is provided. A resin (e.g. plastic or cellulose) is heated and a quaternary salt is added. The resulting admixture is used in forming a material that embodies customized characteristics. In another embodiment, a halogen-containing polymer has a quaternary molecule covalently bonded to it that results in customized properties.

IPC Classes  ?

• C08F 8/44 - Preparation of metal salts or ammonium salts
• C08F 8/40 - Introducing phosphorus atoms or phosphorus-containing groups
• C08F 114/06 - Vinyl chloride

Abstract

A robot for cleaning and inspecting wind turbine blades. The robot has a module that adheres to the blade using a vacuum force. The robot also has a cleaning compartment is divided into two sections that are connected by a flexible section. The cleaning compartment is flexible such that it adapts to convex and concave curvatures on the blade.

IPC Classes  ?

• A47L 1/06 - Hand implements
• B08B 5/04 - Cleaning by suction, with or without auxiliary action
• F03D 80/55 - Cleaning
• B08B 1/00 - Cleaning by methods involving the use of tools
• B08B 3/02 - Cleaning by the force of jets or sprays

Abstract

An electro-optical converter that converts an electric signal to an optical signal. An optical signal is dragged from one optical channel to another optical channel using exciton polaritons that are generated in a layer that is adjacent the optical channels. The exciton polaritons are generated in response to an electrical signal which thereby results in the selective production of the optical signal.

IPC Classes  ?

• G02F 1/31 - Digital deflection devices
• G02F 1/313 - Digital deflection devices in an optical waveguide structure

Abstract

An ultra-hard carbon film is formed by the uniaxial compression of thin films of graphene. The graphene films are two or three layers thick (2-L or 3-L). High pressure compression forms a diamond-like film and provides improved properties to the coated substrates.

IPC Classes  ?

• C30B 33/00 - After-treatment of single crystals or homogeneous polycrystalline material with defined structure
• C01B 32/194 - After-treatment
• A41D 31/24 - Resistant to mechanical stress, e.g. pierce-proof
• A42B 3/04 - Parts, details or accessories of helmets
• C30B 23/02 - Epitaxial-layer growth
• C30B 29/02 - Elements
• F41H 5/04 - Plate construction composed of more than one layer

Abstract

A thin film that has a flexible polymer layer and a peptide layer. The peptide layer is disposed on the flexible polymer layer and has a peptide selected from HYF, DYF and YFD. The thin film reversibly curves with changes in humidity.

IPC Classes  ?

• F03G 7/06 - Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying, or the like
• C07K 5/087 - Tripeptides the side chain of the first amino acid containing carbocyclic rings, e.g. Phe, Tyr
• C07K 5/093 - Tripeptides the side chain of the first amino acid containing more carboxyl groups than amino groups, or derivatives thereof, e.g. Asp, Glu, Asn
• C07K 5/097 - Tripeptides the first amino acid being heterocyclic, e.g. Pro, His, Trp, e.g. thyroliberin, melanostatin
• C08L 7/00 - Compositions of natural rubber
• C08L 21/02 - Latex
• C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
• C08L 69/00 - Compositions of polycarbonatesCompositions of derivatives of polycarbonates
• C08L 79/08 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors
• C08L 83/04 - Polysiloxanes

Abstract

Methods and systems for treating ALS and related motor neuron diseases using multi-site neuromodulation are disclosed.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
• A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
• A61N 1/20 - Applying electric currents by contact electrodes continuous direct currents
• A61N 1/378 - Electrical supply

Abstract

The present disclosure provides inhibitors of bunyavirus of the formula: wherein the variables are defined herein. These inhibitors may be used to treat an infection of Rift Valley phlebovirus, hantavirus, and La Crosse virus, or Crimean-Congo Hemorrhagic fever.

IPC Classes  ?

• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
• A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
• A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
• A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
• A61K 31/4412 - Non-condensed pyridinesHydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
• A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
• A61P 31/14 - Antivirals for RNA viruses

Abstract

A method of controlled production of luminescent diamond particles exhibiting luminescence in selected specific spectral ranges is provided. The method comprises taking diamond particles containing dopant atoms in the diamond core, irradiating the particles with high energy radiation, and annealing the irradiated diamond particles at a target temperature in the temperature range of about 1400° C.-2200° C. to form luminescent diamond particles where the specific spectral range of luminescence is controlled by the target temperature of the annealing process, the irradiation dose, and the type of dopant atoms. Duration of the annealing and the temperature ramp up and ramp down times should be short enough to minimize or prevent significant graphitization of the particles. Duration of the temperature ramp up time should be short enough to minimize formation of color centers that might form at temperatures below the target temperature.

IPC Classes  ?

• C30B 29/04 - Diamond
• C01B 32/28 - After-treatment, e.g. purification, irradiation, separation or recovery
• C09K 11/65 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing carbon
• C30B 1/02 - Single-crystal growth directly from the solid state by thermal treatment, e.g. strain annealing

Abstract

Peptide formulations of a general formula of X-mtp53ODP, where mtp53ODP is a peptide that binds to tetrameric mp53 tetramers in vivo. X is a detection agent, such a fluorophore or radioligand, and/or a DNA-damaging agent. The primary structures of suitable mtp53ODPs are given as SEQ ID NOS: 1-8.

IPC Classes  ?

• A61K 51/08 - Peptides, e.g. proteins
• A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
• A61K 49/00 - Preparations for testing in vivo

Abstract

A metallic electrode comprises an electroactive material comprising zinc, aluminum, lithium, magnesium, silver, brass, copper, stainless steel, nickel, selenium, or any combination thereof, and an additive comprising a metal selected from the group consisting of bismuth, copper, indium, a salt thereof, an oxide thereof, and any combination thereof. The additive is plated in a layer on the electroactive material.

IPC Classes  ?

• H01M 4/04 - Processes of manufacture in general
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides
• C25D 3/54 - ElectroplatingBaths therefor from solutions of metals not provided for in groups
• H01M 4/26 - Processes of manufacture

Abstract

A method for enhancing extracellular vesicle production is described. A peptide that induces polymer formation is incubated with a cell culture which results in enhanced EV production. The peptide penetrates the cells and subsequently polymerizes upon exposure to enzymes (e.g. phosphatase) within the cell. The cells that contain the newly formed polymers have an increased production of EVs. These EVs can be harvested using centrifugation techniques.

IPC Classes  ?

• C12P 21/00 - Preparation of peptides or proteins
• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

Abstract

A battery includes a cathode compartment, a catholyte solution disposed within the cathode compartment, an anode compartment, an anolyte solution disposed within the anode compartment, a separator disposed between the cathode compartment and the anode compartment, and a flow system configured to provide fluid circulation in the cathode compartment and the anode compartment. The catholyte solution and the anolyte solution have different compositions.

IPC Classes  ?

• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 4/04 - Processes of manufacture in general
• H01M 4/66 - Selection of materials
• H01M 4/74 - Meshes or woven materialExpanded metal
• H01M 10/0563 - Liquid materials, e.g. for Li-SOCl2 cells

Abstract

Compounds with anti-viral properties are provided that are based on the following structures: A variety of heteroaromatic groups have been found to be biologically active against viral infections. In some embodiments, a dimeric compound is provided with each monomer linked by a repeating glycol linking group.

IPC Classes  ?

• A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
• A61K 31/335 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
• A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
• A61K 31/4192 - 1,2,3-Triazoles
• A61P 31/14 - Antivirals for RNA viruses

Abstract

A device for storage and transport of biological samples. Multiple trays are assembled into a stack with sample tubes constrained between adjacent trays. The surface of each tray has radial grooves sized to hold the sample tubes. Each tray is secured to an adjacent tray with a bolt or snap-fit connector.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• A61J 1/16 - Holders for containers
• B01L 9/06 - Test-tube standsTest-tube holders

Abstract

A battery comprises a housing, an electrolyte disposed in the housing, a cathode disposed in the housing, an anode disposed in the housing and comprising an anode material comprising: zinc or zinc oxide, an electrocoagulant material selected from the group consisting of: aluminum, iron, titanium, calcium, zirconium, a hydroxide thereof, a salt thereof, an oxide thereof, and a combination thereof, and a binder.

IPC Classes  ?

• H01M 4/42 - Alloys based on zinc
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/26 - Selection of materials as electrolytes

Abstract

Provided herein are biosensors and methods for detecting an odorant ligand using one or more populations of olfactory sensory neurons, or cilia derived therefrom, where each population preferentially expresses an odorant receptor recognizing said odorant ligand. In embodiments, the olfactory sensory neurons, or cilia derived therefrom, comprise a nucleic acid sequence encoding a tetracycline transactivator or a reverse tetracycline transactivator protein; a nucleic acid sequence comprising a tetracycline operator sequence; and a nucleic acid sequence encoding the OR.

IPC Classes  ?

• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12N 5/07 - Animal cells or tissues
• C12N 5/0793 - Neurons
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions

Abstract

A rotary engine that generates electricity using differences in relative humidity. A water-responsive material expands and contracts as water evaporates which drives the rotation of two wheels. The rotary motion drives an electrical generator which produces electricity. In another embodiment, the water-responsive material is used to actuate an artificial muscle of a robotic device.

IPC Classes  ?

• C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
• C09D 105/00 - Coating compositions based on polysaccharides or on their derivatives, not provided for in groups or
• B25J 9/00 - Programme-controlled manipulators

Abstract

A method for detecting an airborne object. Electromagnetic radiation is emitted from a transmitter to overlap with a receiver's field of view. When an airborne object enters the field of view, the electromagnetic radiation interacts with moving airfoils on the airborne object to produce reflected and scattered electromagnetic radiation. The reflected and scattered electromagnetic radiation is analyzed to detect, classify and/or determine the orientation of the airborne object.

IPC Classes  ?

• G01S 13/42 - Simultaneous measurement of distance and other coordinates
• G01S 13/56 - Discriminating between fixed and moving objects or between objects moving at different speeds for presence detection
• G01S 7/41 - Details of systems according to groups , , of systems according to group using analysis of echo signal for target characterisationTarget signatureTarget cross-section
• G01S 13/34 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated using transmission of continuous, frequency-modulated waves while heterodyning the received signal, or a signal derived therefrom, with a locally-generated signal related to the contemporaneously transmitted signal

Abstract

A method for treating a fluid is provided. Particles are coated with quaternary ammonium or phosphonium compounds (“quats”). Fluid is passed over the particles. The biocidal properties of the quats treats the fluid.

IPC Classes  ?

• C02F 1/50 - Treatment of water, waste water, or sewage by addition or application of a germicide or by oligodynamic treatment
• A01N 33/12 - Quaternary ammonium compounds
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A61L 9/00 - Disinfection, sterilisation or deodorisation of air

Abstract

A device for generating singlet oxygen is provided. The device has a sensitizer that converts triplet oxygen to single oxygen upon exposure to light. The device is configured to keep the sensitizer from contacting external fluids.

IPC Classes  ?

• A61N 5/06 - Radiation therapy using light
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61L 2/18 - Liquid substances
• A61L 2/26 - Accessories
• C02F 1/50 - Treatment of water, waste water, or sewage by addition or application of a germicide or by oligodynamic treatment
• C02F 1/72 - Treatment of water, waste water, or sewage by oxidation
• A01K 61/13 - Prevention or treatment of fish diseases
• A01K 63/04 - Arrangements for treating water specially adapted to receptacles for live fish
• A01K 63/06 - Arrangements for heating or lighting in, or attached to, receptacles for live fish
• C02F 103/20 - Nature of the water, waste water, sewage or sludge to be treated from animal husbandry

Abstract

A battery includes a housing, an electrolyte disposed in the housing, an anode disposed in the housing, and an electrode disposed in the housing and comprising an electrode material comprising manganese dioxide, and a conductive carbon coated with a metallic layer. The use of the conductive carbon coated with the metallic layer can help to control the effects of other ions such as zincate on the manganese dioxide during discharge or cycling of the battery.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/26 - Processes of manufacture
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers

Abstract

A system and method for forming a metallic ion intercalated layered structure can include a housing, an electrolyte disposed in the housing, a counter-electrode disposed in the housing, and a working electrode disposed in the housing. The working electrode comprises a metallic support; and an electrode paste. The electrode paste can include an active material and a binder. The system can be used to form a layered structure having metallic ions from the metallic support intercalated into the layered structure based on cycling the working electrode.

IPC Classes  ?

• H01M 4/04 - Processes of manufacture in general
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

4 per square centimeter, and having surfaces that are ion milled instead of mechanically polished. The defect centers can be SiV centers induced by silicon doping during CVD diamond formation, and/or NV0 centers formed by nitrogen doping followed by applying electron beam irradiation of the diamond plate and annealing.

IPC Classes  ?

• G01T 1/20 - Measuring radiation intensity with scintillation detectors
• C30B 25/20 - Epitaxial-layer growth characterised by the substrate the substrate being of the same materials as the epitaxial layer
• C30B 33/04 - After-treatment of single crystals or homogeneous polycrystalline material with defined structure using electric or magnetic fields or particle radiation
• C30B 29/04 - Diamond
• C30B 25/02 - Epitaxial-layer growth
• G01T 1/29 - Measurement performed on radiation beams, e.g. position or section of the beamMeasurement of spatial distribution of radiation
• C30B 33/10 - Etching in solutions or melts
• C30B 33/02 - Heat treatment
• H01L 31/0368 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their crystalline structure or particular orientation of the crystalline planes including polycrystalline semiconductors

Abstract

This disclosure describes three novel bisthioether stapled peptides as allosteric inhibitors of Polycomb Repressive Complex 2 (PRC2) catalytic function with demonstrated cell permeability, potent activity in physiological conditions, and strong antiproliferative effects on cancer cells. These inhibitors target, for the first time, two protein interfaces in PRC2 that are crucial for its proper assembling and thus for its histone methyltransferase activity.

IPC Classes  ?

• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids

Abstract

Methods, devices, and systems for treating spasticity, hypertonia or dystonia are disclosed. Treatment involves applying a source of direct current to one or more locations in a subject (animal, human, or other sentient being). Locations for application of direct current include the spinal column, peripheral nerves, and the cranium. The delivery of direct current is adjusted to change biological activity of or level of gene expression and/or protein expression of target molecule NKCC1.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
• A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
• A61N 1/20 - Applying electric currents by contact electrodes continuous direct currents
• A61N 1/24 - Electromedical belts with built-in power source
• A61P 25/14 - Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Abstract

A zinc electrode comprises an anode material, the anode material comprising: an electroactive material comprising at least one of zinc or a compound comprising zinc, a stabilizer additive comprising at least one of: bismuth, copper, indium, a compound comprising bismuth, a compound comprising copper, a compound comprising indium, or any combination thereof, a conductive additive, and a binder.

IPC Classes  ?

• H01M 4/10 - Processes of manufacture of pressed electrodes with central core, i.e. dollies
• H01M 4/134 - Electrodes based on metals, Si or alloys
• H01M 10/24 - Alkaline accumulators
• H01M 4/02 - Electrodes composed of, or comprising, active material