Metal-organic frameworks (MOFs) comprising square arrays of nickel cationic centers linked by N-donor organic ligands and pillared with tungsten oxyfluoride anion are described. In an exemplary MOF, the N-donor organic ligands are pyrazine and the MOF has a pore size of less than about 7 angstroms. Methods of using the MOF to selectively capture carbon dioxide, e.g., from gas compositions comprising nitrogen and/or methane, are also described.
A supercritical ethylene extraction process for selectively recovering a phenolic compound from bio-crude and/or bio-oil comprises providing a reactor containing bio-crude and/or bio-oil, wherein the reactor has an operating pressure, introducing an ethylene solvent at the operating pressure to the reactor, and using the ethylene solvent at the operating pressure to extract the extracted portion from the feedstock, wherein the extracted portion comprises the selected phenolic compound at a concentration equal to or greater than 70 wt % on a dry basis.
Synthesis gas containing nitrogen as the majority component is processed to increase the hydrogen to carbon dioxide ratio. Nitrogen, carbon dioxide, and other contaminants are subsequently removed by a purification unit to produce a purified hydrogen gas stream. A recycle stream within the purification unit helps achieve a hydrogen purity greater than 99.9 percent, and hydrogen recovery greater than 99 percent.
C01B 3/56 - Separation of hydrogen or hydrogen containing gases from gaseous mixtures, e.g. purification by contacting with solidsRegeneration of used solids
C01B 3/12 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents by reaction of water vapour with carbon monoxide
C01B 3/50 - Separation of hydrogen or hydrogen containing gases from gaseous mixtures, e.g. purification
A heat and mass transfer assembly is described, which in various implementations may be constituted as a packing element including a plate array including heat transfer plates and mass transfer plates in a modular structure in which the number of heat transfer plates and mass transfer plates may be varied to effect desired levels of heat and mass transfer, and multiple packing elements can be integrated in a heat and mass transfer packing assembly, to carry out a wide variety of fluid contacting processes.
7.
METHODS, SYSTEMS, AND DEVICES FOR DETERMINING A PRESENCE OR CONCENTRATION OF A CHEMICAL IN A SAMPLE BASED ON IMAGE ANALYSIS
Disclosed herein are systems, methods, and devices for determining a presence or concentration of a chemical in a sample based on image analysis. In one embodiment, a computing system for image analysis includes one or more hardware computer processors configured to execute software instructions and one or more storage devices storing software instructions for execution by the one or more hardware computer processors configured to cause the computing system to perform the following steps. The computing system receives imaging data of at least one sample droplet of a sample and at least one reagent. One or more imaging properties are identified from the imaging data and a result is generated. The result indicates the presence or concentration of a chemical in the sample based on the identified imaging properties. The computing system stores the imaging data and the result.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 1/38 - Diluting, dispersing or mixing samples
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
8.
METHOD FOR THE CAPTURE OF CARBON DIOXIDE USING OXYFLUORIDE PHYSISORBENTS
Metal-organic frameworks (MOFs) comprising square arrays of nickel cationic centers linked by N-donor organic ligands and pillared with tungsten oxyfluoride anion are described. In an exemplary MOF, the N-donor organic ligands are pyrazine and the MOF has a pore size of less than about 7 angstroms. Methods of using the MOF to selectively capture carbon dioxide, e.g., from gas compositions comprising nitrogen and/or methane, are also described.
B01D 53/04 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
Heteroatom-doped acenes, e.g., acenes doped with nitrogen and sulfur atoms, are described. The heteroatom-doped acenes can be redox-active and/or can include nitrogen substituents that can tune the solubility of the heteroatom-doped acene in non-protic polar solvents. Electrolytes and batteries comprising the heteroatom-doped acenes are also described. In addition, a method of synthesizing heteroatom-doped acenes via aromatic nucleophilic substitution reactions is described.
H01M 10/0564 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes the electrolyte being constituted of organic materials only
H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells
10.
ADSORPTIVE COATINGS FOR METAL SURFACES AND RELATED METHODS
Curable coating compositions and methods of coating the surfaces of objects, such as metal objects, are described. The coating compositions can include organic and/or inorganic solid adsorbent agents and provide durable cured coating layers on metal object surfaces that can be used to adsorb select molecules, such as carbon dioxide or water.
B05D 7/14 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to metal, e.g. car bodies
11.
DEVICE AND METHOD FOR DETECTION OF PARTICLES USING A LINE LASER
A particle detector system for particle analysis. The system has a detection chamber for introduction of a fluid stream having particles, a light source configured to irradiate the particles across a two-dimensional plane in the detection chamber. and a light detector configured to detect either light scattered by particles or light emitted from the particles.
A suspension comprises a nano-crystalline metal organic framework suspended in a polymeric solution. The nano-crystalline metal organic framework comprises micropores having an average diameter in the range of 0.5-5 nm, and the nano-crystalline metal organic framework is substantially homogenously dispersed in the polymeric solution, which comprises a first polymeric material dissolved in a non-aqueous solvent.
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography
B01D 53/22 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
13.
NANOSTRUCTURED SILICON CARBONACEOUS COMPOSITE MATERIAL AND METHODS FOR PRODUCING THE SAME
An anode material for a lithium ion battery comprises a carbonaceous silicon composite material. The composite material comprises Si nanoparticles, and nanostructured and microporous graphitic carbon and/or silicon carbide, wherein the graphitic carbon and/or silicon carbide are derived at least in part from carbonized metal organic framework.
C01B 33/025 - Preparation by reduction of silica or silica-containing material with carbon or a solid carbonaceous material, i.e. carbo-thermal process
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Compiling and analyzing statistics, data and other sources of information for business purposes Downloadable data sets in the field of Epidemiologic Research, Public Health, Health Equity, Community Planning; Data sets in the field of Epidemiologic Research, Public Health, Health Equity, Community Planning recorded on computer media; Downloadable .csv files featuring data related to Epidemiologic Research, Public Health, Health Equity, Community Planning Providing non-downloadable software featuring an interactive map
16.
METHODS, SYSTEMS, AND DEVICES FOR AUTOMATED PERSONALIZED CONTROL OF BUILDING SYSTEMS
Disclosed herein are methods, systems, and devices for automated personalized control of building systems. According to one embodiment, a method is implemented on a computing system. The method includes receiving wearable device health data associated with a plurality of occupants associated with a building and determining a plurality of settings for a plurality of appliances associated with the building based on the wearable device health data.
G05B 19/042 - Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
17.
DEPOLYMERIZATION OF POLYMERS WITH AMMONIA AND AMINES
A process for depolymerizing a polymer comprises reacting the polymer with a nitrogen-containing compound in the presence of a catalyst whereby the polymer is depolymerized into one or more monomers. The catalyst comprises carbonate and an element in group 1 or group 2 of the periodic table. The nitrogen-containing compound comprises ammonia, an amine reagent, or a combination of ammonia and an amine reagent. The polymer comprises polyamide, polyester, polycarbonate, polyurethane, polybutylene terephthalate (PBT), polyethylene terephthalate (PET), lignocellulosic material, or combinations thereof.
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
18.
SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM
Non-peptide, small molecule antagonists of the relaxin family peptide 3 receptor (RXPP3) that can inhibit relaxin-3 activity are described. The compounds can include a pyrrolidone or piperidone substituted with an aryl amide. Also described are methods of preparing the antagonists and methods of using the antagonists to treat diseases, disorders and conditions, such as obesity, alcoholism and other substance abuse and/or addiction-related conditions.
C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
3322, or a pharmaceutically acceptable ester, amide, salt, solvate, prodrug, or isomer thereof. Such compounds may be used to treat conditions for which the cannabinoid receptor system has been implicated, such as metabolic syndromes and substance use disorders.
A network-connected decentralized water treatment monitoring system and operations and maintenance tracker including at least one internet-connected sensor and an integrated software platform that can be used by large facilities and/or organizations with multiple facilities that manage and maintain decentralized drinking water treatment systems (e.g., point-of-use filters) or processes (e.g., faucet flushing) at one or numerous locations. At least one sensor is installed upstream or downstream of a decentralized water treatment consumable or process and measures water data, including but not limited to the volume of water treated over time, and alerts the user when maintenance actions are required to maintain water quality. The water data is wirelessly transmitted to a cloud environment for real-time remote monitoring of water use, water quality, and treatment status.
The University of North Carolina at Chapel Hill (USA)
RESEARCH TRIANGLE INSTITUTE (USA)
Inventor
Hickey, Anthony James
Stewart, Ian Edward
Abstract
Devices and methods for generating an aerosol of a therapeutic agent and methods of using and preparing the same are disclosed. The device includes a heatable porous substrate (e.g., a porous metal or metal alloy) embedded with a composition containing a vaporizable carrier compound (e.g., a phospholipid) and at least one therapeutic agent. The device can be incorporated into a delivery device, such as a metered dose inhaler or an exposure chamber. When the heatable porous substrate is heated, such as by resistive heating, the carrier compound is vaporized and both it and the at least one therapeutic agent are carried out of the porous substrate and, upon cooling, form aerosol particles comprising the at least one therapeutic agent.
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 11/00 - Drugs for disorders of the respiratory system
C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
C07D 417/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
The present disclosure provides novel arylsulfonamide compounds as embodiments of the present disclosure. The compounds are believed to be orexin receptor agonists, useful for the treatment of diseases and conditions caused by reduced activity of orexin.
C07C 311/37 - Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
A61K 31/4406 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
A61K 31/4409 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
A61K 31/4418 - Non-condensed pyridinesHydrogenated derivatives thereof having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4453 - Non-condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C07C 237/42 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
C07D 277/56 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
C07D 295/16 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
C07D 333/38 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
24.
SYSTEMS, METHODS, AND DEVICES FOR DETECTING VIRAL RESPIRATORY ILLNESS IN PRESYMPTOMATIC AND ASYMPTOMATIC INFECTED PERSONS
Disclosed herein are systems, methods, and devices of detecting illness in presymptomatic and asymptomatic infected persons using wearable sensor technology. In a first embodiment, a method is implemented on a computing device, the method includes receiving first sensor data associated with the person over a first period of time and applying the first sensor data to a multi-variate detection model. The method further includes receiving second sensor data associated with the person over a second period of time and applying the second sensor data to the multi-variate detection model. Further the method includes determining a probability value of the illness in the person using the multi-variate detection model and transmitting the probability value to a user interface (UI).
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/28 - Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
A61B 5/352 - Detecting R peaks, e.g. for synchronising diagnostic apparatusEstimating R-R interval
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Flow meters; Water meters; Computer hardware and recorded software system for remotely monitoring environmental conditions and controlling devices within a building, facility, grounds, or designated spatial area; Scientific instrumentation for measuring water flow rate, cumulative water flow, power usage, not for medical use Water meter reading and data analysis; Electronic monitoring and reporting of water flow rate, cumulative water flow, and power consumption using computers or sensors; Electronic monitoring of water flow rate, cumulative water flow, and power consumption using computers and sensors; Monitoring water flow rate, cumulative water flow, and power consumption for quality control purposes; Monitoring water filters, faucets, water treatment apparatuses to ensure proper functioning; Providing an interactive web site featuring technology that enables users to enter, access, track, manage, monitor, and generate information and reports regarding their in-house building water treatment programs
Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.
A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 25/00 - Drugs for disorders of the nervous system
27.
METHOD TO CONTROL SYNGAS COMPOSITION FROM AN ENGINE-BASED SYNGAS GENERATOR
The present disclosure provides a process for controlling syngas composition from an internal combustion engine-based syngas generator. While air is typically used as an oxidant, with nitrogen (N2) as a diluent, this results in expensive downstream compression, and low feedstock conversion efficiencies. This disclosure provides CO2 as a diluent to reduce N2 concentration in the syngas. In some embodiments, the CO2 diluent may be from either a biogas processing coupled with methanol, DME, and/or hydrocarbon production; or natural gas processing coupled with Fischer-Tropsch (FT) synthesis and/or other hydrocarbon synthesis.
C01B 3/36 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of gaseous or liquid organic compounds with gasifying agents, e.g. water, carbon dioxide, air by reaction of hydrocarbons with gasifying agents using oxygen or mixtures containing oxygen as gasifying agents
C10G 2/00 - Production of liquid hydrocarbon mixtures of undefined composition from oxides of carbon
C07C 29/151 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases
C07C 41/09 - Preparation of ethers by dehydration of compounds containing hydroxy groups
28.
SPRAY-DRIED METAL-ORGANIC FRAMEWORKS FOR TREATMENT AND/OR DIAGNOSIS OF PULMONARY DISEASE
Spray-dried metal-organic frameworks (MOFs) comprising therapeutic and/or diagnostic metal ions and therapeutic and/or diagnostic organic ligands are described. Both the metal ion and organic ligand can have activity related to the treatment and/or diagnosis of a pulmonary disease or disorder, such as tuberculosis, or another disease related to a pulmonary infection. The MOFs can be adminstered to subjects via inhalation (e.g., as aerosols). Methods of treating and diagnosing pulmonary diseases or disorders are also described.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
Disclosed herein are systems, methods, and devices of detecting illness in presymptomatic and asymptomatic infected persons using wearable sensor technology. In a first embodiment, a method is implemented on a computing device, the method includes receiving first sensor data associated with the person over a first period of time and applying the first sensor data to a multi-variate detection model. The method further includes receiving second sensor data associated with the person over a second period of time and applying the second sensor data to the multi-variate detection model. Further the method includes determining a probability value of the illness in the person using the multi-variate detection model and transmitting the probability value to a user interface (UI).
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61K 31/136 - Amines, e.g. amantadine having aromatic rings, e.g. methadone having the amino group directly attached to the aromatic ring, e.g. benzeneamine
A61P 25/30 - Drugs for disorders of the nervous system for treating abuse or dependence
C07C 225/22 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
31.
SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS
Squaramide-based cannabinoid 1 receptor (CB1R) allosteric modulators are described. Exemplary analogs may provide improved potencies and pharmacokinetic properties. Methods of using the analogs to treat diseases mediated by CB1R, such as substance abuse and obesity, are described.
C07C 225/22 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
A61K 31/136 - Amines, e.g. amantadine having aromatic rings, e.g. methadone having the amino group directly attached to the aromatic ring, e.g. benzeneamine
The present disclosure includes peripheral partial agonists of one or more CB receptors, including modulation of CB1, both with and without CB2 selectivity. The compounds of the present disclosure may be useful in the treatment of diseases and disorders mediated by a CB-signaling pathway, including but not limited to pain, gastrointestinal disorders, metabolic disorders, and liver disorders, such as alcoholic steatohepatitis or nonalcoholic steatohepatitis (NASH).
An internal combustion engine is operated at fuel-rich conditions by adjusting one or more operating parameters such as, for example, a throttle, an ignition timing, a load coupled to the engine, a fuel pressure, power to a supercharger, and power to a preheater to maintain a specified engine speed and a temperature of an exhaust gas. Operating the engine under these conditions allows the engine to function as a reformer producing a synthesis gas comprising hydrogen and carbon monoxide.
F02D 41/00 - Electrical control of supply of combustible mixture or its constituents
F02P 5/14 - Advancing or retarding electric ignition sparkControl therefor automatically, as a function of the working conditions of the engine or vehicle or of the atmospheric conditions using mechanical means dependent on specific conditions other than engine speed or engine fluid pressure, e.g. temperature
F02D 41/06 - Introducing corrections for particular operating conditions for engine starting or warming up
Disclosed herein are systems, methods, and devices for determining a presence or concentration of a chemical in a sample based on image analysis. In one embodiment, a computing system for image analysis includes one or more hardware computer processors configured to execute software instructions and one or more storage devices storing software instructions for execution by the one or more hardware computer processors configured to cause the computing system to perform the following steps. The computing system receives imaging data of at least one sample droplet of a sample and at least one reagent. One or more imaging properties are identified from the imaging data and a result is generated. The result indicates the presence or concentration of a chemical in the sample based on the identified imaging properties. The computing system stores the imaging data and the result.
The present disclosure provides novel 4-substituted-phenyl acetamide and arylurea derivatives that act as agonists against GPR88. The compounds of the present disclosure are believed to be useful for the treatment of diseases and conditions caused by physiological processes implicating the orphan receptor GPR88, including diverse brain and behavioral functions such as cognition, mood, movement control, and reward-based learning. GPR88 is emerging as a novel drug target for central nervous system disorders including schizophrenia, Parkinson's disease, anxiety, and addiction. One particular indication for which GPR88 agonists hold promise is alcohol use disorder (AUD).
A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
A61P 25/18 - Antipsychotics, i.e. neurolepticsDrugs for mania or schizophrenia
C07C 235/34 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
C07C 235/36 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
C07C 235/38 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
C07C 235/80 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
C07D 307/52 - Radicals substituted by nitrogen atoms not forming part of a nitro radical
C07D 333/24 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
37.
REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION
A solvent system for the removal of acid gases from mixed gas streams is provided. Also provided is a process for removing acid gases from mixed gas streams using the disclosed solvent systems. The solvent systems may be utilized within a gas processing system.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
B01D 53/78 - Liquid phase processes with gas-liquid contact
The present disclosure provides novel 4-substituted-phenyl acetamide and arylurea derivatives that act as agonists against GPR88. The compounds of the present disclosure are believed to be useful for the treatment of diseases and conditions caused by physiological processes implicating the orphan receptor GPR88, including diverse brain and behavioral functions such as cognition, mood, movement control, and reward-based learning. GPR88 is emerging as a novel drug target for central nervous system disorders including schizophrenia, Parkinson's disease, anxiety, and addiction. One particular indication for which GPR88 agonists hold promise is alcohol use disorder (AUD).
C07C 235/34 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
C07C 235/36 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
C07C 235/80 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
C07D 307/52 - Radicals substituted by nitrogen atoms not forming part of a nitro radical
C07D 333/24 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 491/107 - Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 231/14 - Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D 403/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C07D 407/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 403/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 413/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 417/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 417/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
A supercritical ethylene extraction process for selectively recovering a phenolic compound from bio-crude and/or bio-oil comprises providing a reactor containing bio-crude and/or bio-oil, wherein the reactor has an operating pressure, introducing an ethylene solvent at the operating pressure to the reactor, and using the ethylene solvent at the operating pressure to extract the extracted portion from the feedstock, wherein the extracted portion comprises the selected phenolic compound at a concentration equal to or greater than 70wt% on a dry basis.
C10G 1/00 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal
C10G 1/04 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by extraction
C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
41.
SUPERCRITICAL ETHYLENE EXTRACTION PROCESS FOR SELECTIVELY RECOVERING PHENOLIC COMPOUNDS FROM BIO-CRUDE AND/OR BIO-OIL
A supercritical ethylene extraction process for selectively recovering a phenolic compound from bio-crude and/or bio-oil comprises providing a reactor containing bio-crude and/or bio-oil, wherein the reactor has an operating pressure, introducing an ethylene solvent at the operating pressure to the reactor, and using the ethylene solvent at the operating pressure to extract the extracted portion from the feedstock, wherein the extracted portion comprises the selected phenolic compound at a concentration equal to or greater than 70wt% on a dry basis.
C07C 41/34 - SeparationPurificationStabilisationUse of additives
C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
C10G 1/04 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by extraction
A reservoir device comprising an active agent formulation contained within a reservoir is described. The active agent formulation comprises more than one active agent. The reservoir is defined by a biodegradable, permeable polymer membrane. The membrane allows for diffusion of the more than one active agent of the formulation there through when positioned subcutaneously in a body of a subject.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61K 31/57 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
The present disclosure provides perovskite catalytic materials and catalysts comprising platinum-group metals and perovskites. These catalysts may be used as oxygen storage materials with automotive applications, such as three-way catalysts. They are also useful for water or CO2 reduction, or thermochemical energy storage.
B01J 23/89 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with noble metals
B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
F01N 3/10 - Exhaust or silencing apparatus having means for purifying, rendering innocuous, or otherwise treating exhaust for rendering innocuous by thermal or catalytic conversion of noxious components of exhaust
41 - Education, entertainment, sporting and cultural services
Goods & Services
Arrangement of conferences for educational purposes;
arranging and conducting educational conferences in the
fields of survey research, data science, statistics, and
computer science; educational services, namely, developing,
arranging, and conducting educational conferences and
programs and providing courses of instruction in the field
(s) of survey research, data science, statistics, and
computer science; educational services, namely, conducting
seminars, conferences, workshops in the fields of survey
research, data science, statistics, and computer science and
distribution of material in connection therewith;
organization of conferences, exhibitions and competitions;
providing and distributing materials, publications,
programs, books, newsletters, website, blog in the field of
survey research, data science, statistics, and computer
science for conferences for educational purposes (terms
considered too vague by the International Bureau - Rule 13
(2) (b) of the Regulations).
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing training, seminars, educational services being non-downloadable webinars, and one-on-one consultation, all in the fields of contaminant education, sample collection and shipment, laboratory testing, risk communication, and risk mitigation; providing an Internet website portal in the field of contaminant education Environmental contaminant testing services, testing of materials in the nature of contaminants, and contaminant testing in the nature of detection of contaminant in water; Contaminant testing in the nature of scientific research and analysis of the chemical, heavy metal, and physical properties of samples for the presence of contaminants; Providing information in the field of environmental health, water quality, and detection of chemical contaminants in soil and water via a website; Conducting chemical surveys, namely, strength and chemical testing of potable water, surface water, groundwater, childcare and education centers; Providing an Internet website portal in the fields of potable water, water, and aqueous solutions sample collection and laboratory chemical, heavy metal, and organics testing
41 - Education, entertainment, sporting and cultural services
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Arrangement of conferences for educational purposes;
arranging and conducting educational conferences in the
fields of survey research, data science, statistics, and
computer science; educational services, namely, developing,
arranging, and conducting educational conferences and
programs and providing courses of instruction in the field
(s) of survey research, data science, statistics, and
computer science; educational services, namely, conducting
seminars, conferences, workshops in the fields of survey
research, data science, statistics, and computer science,
and distribution of material in connection therewith;
organization of conferences, exhibitions and competitions;
providing and distributing materials, publications,
programs, books, newsletters, website, blog in the field of
survey research, data science, statistics, and computer
science for conferences for educational purposes (term
considered too vague by the International Bureau - Rule 13
(2) (b) of the Regulations).
47.
METHOD AND APPARATUS FOR SPATIAL CONTROL OF CELLULAR GROWTH
A three-dimensional cell growth containment article is described, which includes a molded body channelized by removal of sacrificial channelizing element(s) therefrom, so that the molded body contains one or more channel(s) therein, with a matrix material in at least one of such channel(s) that is supportive of three-dimensional cell growth in the matrix material. A method for making such articles is also described, in which a molded body is formed with one or more sacrificial channelizing element(s) therein, following which the sacrificial channelizing element(s) are removed. The three-dimensional cell growth containment articles of the present disclosure may be utilized in any applications in which there exists a need to reproducibly generate three-dimensional cellular structures, e.g., islet transplantation for diabetes treatment, transplantation of hormone secreting cells, cellular scaffolds for wound healing, and generation of tissue engineering structures to regain structural usefulness for orthopedic applications.
The present disclosure provides novel solid sorbents synthesized by the reaction of polyamines with polyaldehyde phosphorus dendrimer (P-dendrimer) compounds for metal sequestration. The sorbents are highly stable and exhibit desirable thermodynamics and reaction kinetics with a wide variety of metals including heavy metals and rare earth elements. The sorbents can be easily regenerated for repeated use to extract metals from an aqueous solution. The materials are stable to aqueous and organic media, as well as strong acid and bases. The sorbents maintain full capacity over many cycles of use.
B01J 20/04 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.
A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 25/00 - Drugs for disorders of the nervous system
50.
Design, Fabrication, and Characterization of Nanoplastics and Microplastics
Provided by the inventive concept or nanoplastic or microplastic particles, reference standard materials including nanoplastic or microplastic particles, methods of using, and methods of preparing the same. Uses of the nanoplastic and/or microplastic particles of the inventive concept include tracking of nanoplastic and/or microplastic particle dispersion/distribution in environmental and/or biological systems, as well as in organisms that are within the environment.
The present disclosure relates to delivery and release compositions, systems, and methods of use thereof. In particular, the present disclosure relates to degradable polymeric systems including a first epoxy-containing monomer and a second, different epoxy-containing monomer, wherein the degradable polymeric system is crosslinked, and wherein one of the first epoxy-containing monomer and the second, different epoxy-containing monomer includes one or more ester groups; delivery systems incorporating degradable polymeric systems; and methods for providing cargo to a petroleum reservoir.
A method for reducing the concentration of amines in a wash liquid stream exiting a wash section in an acid gas scrubbing process includes introducing the wash liquid stream exiting the wash section of the acid gas scrubbing process to an adsorbent material, wherein the wash liquid stream has a first concentration of amines. The wash liquid stream having the first concentration of amines is flowed through the adsorbent material, and the adsorbent material retains at least a portion of the amines thereby providing a wash liquid stream having a second, reduced concentration of amines. The wash stream with reduced concentration of amines is recycled back to the wash section to remove amines more effectively from the acid gas being scrubbed. The adsorbent material can be regenerated for reuse. Amine recovered from the regenerated adsorbent material can be recycled to the process for reuse.
C02F 1/28 - Treatment of water, waste water, or sewage by sorption
B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
53.
Solid-state crystallization of metal organic frameworks within mesoporous materials methods and hybrid materials thereof
B01J 20/10 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
C01B 39/00 - Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolitesTheir preparationAfter-treatment, e.g. ion-exchange or dealumination
C01B 39/02 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereofDirect preparation thereofPreparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactantsAfter-treatment thereof
C01B 39/48 - Other types characterised by their X-ray diffraction pattern and their defined composition using at least one organic template directing agent
54.
NON-AQUEOUS SOLVENT FOR REMOVING ACIDIC GAS FROM A PROCESS GAS STREAM FOR HIGH PRESSURE APPLICATIONS
A non-aqueous solvent system configured to remove acidic gas from a gas stream comprises a solution formed of a chemical absorption component and a physical absorption component. The chemical absorption component includes a nitrogenous base, wherein the nitrogenous base has a structure such that it reacts with a portion of the acidic gas. The physical absorption component includes an organic diluent that is non-reactive with the acidic gas and that has a structure such that it absorbs a portion of the acidic gas at a pressure above atmospheric pressure. The solvent system has a solubility with water of less than about 10 g of solvent per 100 mL of water.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
C10L 3/10 - Working-up natural gas or synthetic natural gas
55.
SYSTEMS, METHODS, AND DEVICES FOR DETECTING VIRAL RESPIRATORY ILLNESS IN PRESYMPTOMATIC AND ASYMPTOMATIC INFECTED PERSONS
Disclosed herein are systems, methods, and devices of detecting illness in presymptomatic and asymptomatic infected persons using wearable sensor technology. In a first embodiment, a method is implemented on a computing device, the method includes receiving first sensor data associated with the person over a first period of time and applying the first sensor data to a multi-variate detection model. The method further includes receiving second sensor data associated with the person over a second period of time and applying the second sensor data to the multi-variate detection model. Further the method includes determining a probability value of the illness in the person using the multi-variate detection model and transmitting the probability value to a user interface (UI).
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
The disclosure provides an apparatus, as well as associated systems and methods for removing acid gas components from gas streams. The disclosure provides a rotating packed bed (RPB)-based absorber with a non-aqueous liquid solvent contained therein for treatment of the gas streams, wherein the non-aqueous liquid solvent captures acid components from the gas stream. Various advantages, e.g., with respect to spatial considerations and associated expenses can be realized using the apparatus, systems, and methods described herein.
B01D 53/06 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with moving adsorbents
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
The disclosure provides an apparatus, as well as associated systems and methods for removing acid gas components from gas streams. The disclosure provides a rotating packed bed (RPB)-based absorber with a non-aqueous liquid solvent contained therein for treatment of the gas streams, wherein the non-aqueous liquid solvent captures acid components from the gas stream. Various advantages, e.g., with respect to spatial considerations and associated expenses can be realized using the apparatus, systems, and methods described herein.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
The disclosure provides an apparatus, as well as associated systems and methods for removing acid gas components from gas streams. The disclosure provides a rotating packed bed (RPB)-based absorber with a non-aqueous liquid solvent contained therein for treatment of the gas streams, wherein the non-aqueous liquid solvent captures acid components from the gas stream. Various advantages, e.g., with respect to spatial considerations and associated expenses can be realized using the apparatus, systems, and methods described herein.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
B01D 53/06 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with moving adsorbents
41 - Education, entertainment, sporting and cultural services
Goods & Services
(1) Arranging and conducting educational conferences in the fields of survey research, data science, statistics, and computer science; educational services, namely, developing, arranging, and conducting educational conferences and programs and providing courses of instruction in the field (s) of survey research, data science, statistics, and computer science; educational services, namely, conducting seminars, conferences, workshops in the fields of survey research, data science, statistics, and computer science, and distribution of material in connection therewith; conducting of conferences in the field of survey research, data science, statistics, and computer science; organization of exhibitions for cultural or educational purposes; organization of exhibitions for entertainment purposes; on-line journals, namely, blogs featuring survey research, data science, statistics, and computer science for conferences for educational purpose; providing and distributing materials, namely, providing online non-downloadable electronic publications in the nature of books, newsletters, magazines, pamphlets, and brochures in the field of survey research, data science, statistics, and computer science for conferences for educational purpose.
41 - Education, entertainment, sporting and cultural services
Goods & Services
(1) Arranging and conducting educational conferences in the fields of survey research, data science, statistics, and computer science; educational services, namely, developing, arranging, and conducting educational conferences and programs and providing courses of instruction in the field (s) of survey research, data science, statistics, and computer science; educational services, namely, conducting seminars, conferences, workshops in the fields of survey research, data science, statistics, and computer science, and distribution of material in connection therewith; conducting of conferences in the field of survey research, data science, statistics, and computer science; organization of exhibitions for cultural or educational purposes; organization of exhibitions for entertainment purposes; on-line journals, namely, blogs featuring survey research, data science, statistics, and computer science for conferences for educational purpose; providing and distributing materials, namely, providing online non-downloadable electronic publications in the nature of books, newsletters, magazines, pamphlets, and brochures in the field of survey research, data science, statistics, and computer science for conferences for educational purpose.
61.
DEPOLYMERIZATION OF POLYMERS WITH AMMONIA AND AMINES
A process for depolymerizing a polymer comprises reacting the polymer with a nitrogen-containing compound in the presence of a catalyst whereby the polymer is depolymerized into one or more monomers. The catalyst comprises carbonate and an element in group 1 or group 2 of the periodic table. The nitrogen-containing compound comprises ammonia, an amine reagent, or a combination of ammonia and an amine reagent. The polymer comprises polyamide, polyester, polycarbonate, polyurethane, polybutylene terephthalate (PBT), polyethylene terephthalate (PET), lignocellulosic material, or combinations thereof.
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
62.
DEPOLYMERIZATION OF POLYMERS WITH AMMONIA AND AMINES
A process for depolymerizing a polymer comprises reacting the polymer with a nitrogen-containing compound in the presence of a catalyst whereby the polymer is depolymerized into one or more monomers. The catalyst comprises carbonate and an element in group 1 or group 2 of the periodic table. The nitrogen-containing compound comprises ammonia, an amine reagent, or a combination of ammonia and an amine reagent. The polymer comprises polyamide, polyester, polycarbonate, polyurethane, polybutylene terephthalate (PBT), polyethylene terephthalate (PET), lignocellulosic material, or combinations thereof.
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
42 - Scientific, technological and industrial services, research and design
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Providing temporary use of online non-downloadable software for scientific analysis of laboratory samples; Providing temporary use of online non-downloadable software used in scientific and forensic apparatus in drug detection processes; Research services in the field of forensic science, namely, analysis, detection and isolation of substances in forensic samples; Software as a Service (SAAS) services featuring software for use in analysis, detection and isolation of substances in forensic samples in the field of forensic science
64.
HOT POROUS-SOLID METERING SYSTEMS AND METHODS FOR GENERATION OF THERAPEUTIC AEROSOLS BY EVAPORATION/CONDENSATION
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (USA)
RESEARCH TRIANGLE INSTITUTE (USA)
Inventor
Hickey, Anthony James
Stewart, Ian Edward
Abstract
Devices and methods for generating an aerosol of a therapeutic agent and methods of using and preparing the same are disclosed. The device includes a heatable porous substrate (e.g., a porous metal or metal alloy) embedded with a composition containing a vaporizable carrier compound (e.g., a phospholipid) and at least one therapeutic agent. The device can be incorporated into a delivery device, such as a metered dose inhaler or an exposure chamber. When the heatable porous substrate is heated, such as by resistive heating, the carrier compound is vaporized and both it and the at least one therapeutic agent are carried out of the porous substrate and, upon cooling, form aerosol particles comprising the at least one therapeutic agent.
Provided is a proficiency testing material, and in more particular aspects, a cannabis proficiency testing material comprising: a plant substrate; and at least one chemical and/or microbial contaminant, wherein the at least one chemical and/or microbial contaminant is chemically or physically associated with the plant substrate. Methods of preparing the proficiency testing material and kits including the same are also provided.
Non-peptide, small molecule antagonists of the relaxin family peptide 3 receptor (RXFP3) that can inhibit relaxin-3 activity are described. The compounds can include a pyrrolidone or piperidone substituted with an aryl amide. Also described are methods of preparing the antagonists and methods of using the antagonists to treat diseases, disorders and conditions, such as obesity, alcoholism and other substance abuse and/or addiction-related conditions.
The present disclosure provides novel arylsulfonamide compounds as embodiments of the present disclosure. The compounds are believed to be orexin receptor agonists, useful for the treatment of diseases and conditions caused by reduced activity of orexin.
C07C 237/40 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
C07C 311/37 - Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
C07D 207/06 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
C07D 211/18 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
C07D 213/16 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
C07D 213/24 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
The present disclosure provides novel arylsulfonamide compounds as embodiments of the present disclosure. The compounds are believed to be orexin receptor agonists, useful for the treatment of diseases and conditions caused by reduced activity of orexin.
C07C 311/37 - Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
C07C 237/40 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
C07D 211/18 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
C07D 207/06 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
C07D 213/16 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
C07D 213/24 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
The present disclosure provides a method for treating idiopathic pulmonary fibrosis in a patient in need thereof comprising administering a therapeutically effective amount of an apelin receptor agonist.
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/4418 - Non-condensed pyridinesHydrogenated derivatives thereof having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A61P 11/00 - Drugs for disorders of the respiratory system
70.
HETEROARYL DERIVATIVES AS APELIN RECEPTOR AGONISTS
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
C07D 417/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
A61K 31/4418 - Non-condensed pyridinesHydrogenated derivatives thereof having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
71.
POROUS METAL ORGANIC FRAMEWORK-POLYMER COMPOSITES FOR USE IN DETOXIFYING CHEMICAL WARFARE AGENTS
A metal organic framework (MOF)-polymer composite for detoxifying a chemical warfare agent (CWA) comprises MOF nanoparticles having catalytically active Lewis acid sites and at least one polymer having catalytically active basic sites. The composite is configured such that the at least one polymer is in surrounding relation to the MOF nanoparticles such that at least a portion of the Lewis acid sites of the MOF nanoparticles are in proximal relation to at least a portion of the basic sites of the at least one polymer thereby forming a plurality of proximal acid-base interfaces thus enabling a bifunctional catalytic mechanism for detoxifying the CWA. The MOF-polymer composite can provide CWA detoxification without the presence of a basic compound.
A62D 3/35 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by hydrolysis
A chromium-free catalyst for use in a fluidized bed reactor is described. The catalyst comprises 45-70 wt % Fe2O3, 5-15 wt % CuO, 20-35 wt % Al2O3, 10-20 wt % ZnO, and 1-15 wt % K2CO3. The catalyst has a Davison Index (DI %) of less than or equal to 15. A method for converting carbon monoxide (CO) into carbon-dioxide (CO2) using the catalyst is described. The method includes introducing H2O and CO into a fluidized bed reactor having an operating temperature between about 375° C. and about 450° C. and comprising the chromium free catalyst. The CO conversion is at least 60%.
B01J 8/24 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles according to "fluidised-bed" technique
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
B01J 23/80 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with zinc, cadmium or mercury
B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
B01J 35/10 - Solids characterised by their surface properties or porosity
C01B 3/16 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents by reaction of water vapour with carbon monoxide using catalysts
73.
METHOD TO CONTROL SYNGAS COMPOSITION FROM AN ENGINE-BASED SYNGAS GENERATOR
22222 diluent may be from either a biogas processing coupled with methanol, DME, and/or hydrocarbon production; or natural gas processing coupled with Fischer-Tropsch (FT) synthesis and/or other hydrocarbon synthesis.
C01B 3/36 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of gaseous or liquid organic compounds with gasifying agents, e.g. water, carbon dioxide, air by reaction of hydrocarbons with gasifying agents using oxygen or mixtures containing oxygen as gasifying agents
C07C 29/151 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases
C10G 2/00 - Production of liquid hydrocarbon mixtures of undefined composition from oxides of carbon
F02D 19/06 - Controlling engines characterised by their use of non-liquid fuels, pluralities of fuels, or non-fuel substances added to the combustible mixtures peculiar to engines working with pluralities of fuels, e.g. alternatively with light and heavy fuel oil, other than engines indifferent to the fuel consumed
F02M 21/02 - Apparatus for supplying engines with non-liquid fuels, e.g. gaseous fuels stored in liquid form for gaseous fuels
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
36 - Financial, insurance and real estate services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
45 - Legal and security services; personal services for individuals.
Goods & Services
Downloadable resources, namely, downloadable electronic publications in the form of books, hand-outs, workbooks, blogs, articles, and reports in the field of health care Business consultation; Business organization consulting; business administration; Cost assessment services Financial consultancy and insurance consultancy Education services, namely, providing non-downloadable webinars, seminars, and blogs in the field of healthcare and science; Education services, namely, training healthcare professionals, administrators, and insurance brokers in the field of healthcare and science Scientific and technological services, namely, scientific research, testing and design in the field of healthcare; industrial analysis in the form of consulting services in the field of industrial engineering; Industrial research in the field of healthcare; providing website featuring information in the field of science, namely, scientific research Consulting services in the field of healthcare, namely, chronic disease management, connected care, healthcare access, healthcare data analytics, maternal health, behavioral health, care delivery models, equitable care, social determinants of health, and value-based care; providing website featuring information in the field of healthcare; all of the foregoing explicitly excluding tissue bank services Regulatory compliance consulting in the field of healthcare and health insurance; Providing regulatory compliance information in the field of healthcare and health insurance
Apparatus for testing an electronic smoking (e-smoking) device includes an electronic circuit for electronically activating an e-smoking device and causing the e-smoking device to generate a plurality of puffs by converting a wicking fluid therein into a plurality of puffs without a need for a human to physically contact the e-smoking device during puff generation, and a wireless controller for controlling the electronic circuit. The electronic circuit is configured for activating the e-smoking device to generate the plurality of puffs based on wireless signals received at the wireless controller. The apparatus is further configured for measuring a characteristic of the e-smoking device, which may include a rate of conversion of the wicking fluid to vapor as a function of time for the plurality of puffs.
G01K 7/02 - Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat using thermoelectric elements, e.g. thermocouples
41 - Education, entertainment, sporting and cultural services
Goods & Services
Arranging and conducting educational conferences in the fields of survey research, data science, statistics, and computer science; Educational services, namely, developing, arranging, and conducting educational conferences and programs and providing courses of instruction in the field(s) of survey research, data science, statistics, and computer science; Educational services, namely, conducting seminars, conferences, workshops in the fields of survey research, data science, statistics, and computer science, and distribution of material in connection therewith; Conducting of conferences in the field of survey research, data science, statistics, and computer science; Organization of exhibitions for cultural or educational purposes; Organization of exhibitions for entertainment purposes; On-line journals, namely, blogs featuring survey research, data science, statistics, and computer science for conferences for educational purpose; providing and distributing materials, namely, providing online non-downloadable electronic publications in the nature of books, newsletters, magazines, pamphlets, and brochures in the field of survey research, data science, statistics, and computer science for conferences for educational purpose
41 - Education, entertainment, sporting and cultural services
Goods & Services
Arranging and conducting educational conferences in the fields of survey research, data science, statistics, and computer science; Educational services, namely, developing, arranging, and conducting educational conferences and programs and providing courses of instruction in the field(s) of survey research, data science, statistics, and computer science; Educational services, namely, conducting seminars, conferences, workshops in the fields of survey research, data science, statistics, and computer science, and distribution of material in connection therewith; Conducting of conferences in the field of survey research, data science, statistics, and computer science; Organization of exhibitions for cultural or educational purposes; Organization of exhibitions for entertainment purposes; On-line journals, namely, blogs featuring survey research, data science, statistics, and computer science for conferences for educational purpose; providing and distributing materials, namely, providing online non-downloadable electronic publications in the nature of books, newsletters, magazines, pamphlets, and brochures in the field of survey research, data science, statistics, and computer science for conferences for educational purpose
B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
B01J 23/89 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with noble metals
F01N 3/10 - Exhaust or silencing apparatus having means for purifying, rendering innocuous, or otherwise treating exhaust for rendering innocuous by thermal or catalytic conversion of noxious components of exhaust
2 intermediate material to the nanostructured silicon carbonaceous composite material. Relatively inexpensive and/or recycled materials can be used as precursors in manufacturing the nanostructured silicon carbon composition material, which can be used in various applications, including as silicon anode material in a lithium-ion battery.
C01B 33/025 - Preparation by reduction of silica or silica-containing material with carbon or a solid carbonaceous material, i.e. carbo-thermal process
A membrane assembly for separating a feed liquid into a permeate and a retentate includes a semipermeable membrane and conductive members for applying a voltage effective for charging a semipermeable surface of the membrane, thereby reducing or preventing fouling or scaling of the membrane. The conductive members may be positioned adjacent to the semipermeable membrane, and may be configured as feed spacers or permeate spacers. Alternatively or additionally, the membrane may be electrically conductive. Power from an external source may be supplied to one or more of the conductive members, or also the membrane if conductive, which may be done wirelessly. One or more membrane assemblies may be provided in a container. One or more membrane assemblies may be provided in a stacked configuration, or wrapped around a tube in a spiral configuration.
B01D 71/42 - Polymers of nitriles, e.g. polyacrylonitrile
B01D 71/72 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of groups
A reservoir device comprising an active agent formulation contained within a reservoir is described. The reservoir is defined by a biodegradable, permeable polymer membrane having a thickness of at least 45 μm. The membrane allows for diffusion of an active agent of the formulation there through when positioned subcutaneously in a body of a subject.
An air filtration media with integrated disinfection capability. The media has a collection filter for capture of pathogens, and an ultraviolet (UV) radiation source integrated into the collection filter such that the pathogens collected by the collection filter are exposed to UV radiation from the UV radiation source.
The present invention provides novel diarylurea derivatives (compounds of formula (I)) and their uses. The compounds of the present invention are demonstrated to be allosteric modulators of the CB1 receptor, and therefore useful for the treatment of diseases and conditions mediated by CB1.
C07C 275/38 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms
A61P 25/30 - Drugs for disorders of the nervous system for treating abuse or dependence
C07D 205/04 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
C07D 207/335 - Radicals substituted by nitrogen atoms not forming part of a nitro radical
C07D 215/12 - Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
C07D 239/26 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07D 295/135 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
C07D 333/20 - Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
A reservoir device comprising an active agent formulation contained within a reservoir is described. The active agent formulation comprises more than one active agent. The reservoir is defined by a biodegradable, permeable polymer membrane. The membrane allows for diffusion of the more than one active agent of the formulation there through when positioned subcutaneously in a body of a subject.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/567 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
The present disclosure relates to delivery and release systems, such as core-shell particles. An exemplary composition according to the disclosure can include a degradable polymeric shell surrounding a core that includes a crosslinker, which can encompass a metal, such as chromium. The core-shell particles can be provided with a gel-forming polymer, such as a polyacrylamide, into a subterranean reservoir having conditions such that the shell of the core-shell polymer degrades, and the so-released metal is effective to at least partially crosslink the gel-forming polymer to form a gel. The so-formed gel can be effective to control water flow through the subterranean reservoir, such as in relation to a waterflood of the reservoir.
C09K 8/588 - Compositions for enhanced recovery methods for obtaining hydrocarbons, i.e. for improving the mobility of the oil, e.g. displacing fluids characterised by the use of specific polymers
C09K 8/508 - Compositions based on water or polar solvents containing organic compounds macromolecular compounds
C09K 8/512 - Compositions based on water or polar solvents containing organic compounds macromolecular compounds containing cross-linking agents
C09K 8/516 - Compositions for plastering borehole walls, i.e. compositions for temporary consolidation of borehole walls characterised by their form or by the form of their components, e.g. encapsulated material
E21B 33/138 - Plastering the borehole wallInjecting into the formation
A reservoir device comprising an active agent formulation contained within a reservoir is described. The active agent formulation comprises more than one active agent. The reservoir is defined by a biodegradable, permeable polymer membrane. The membrane allows for diffusion of the more than one active agent of the formulation there through when positioned subcutaneously in a body of a subject.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
A61K 31/567 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Described herein is a catalytic reaction process including introducing one or more gas-phase reactants into a reactor comprising a microporous catalyst having a pore size less than or equal to 2 nm and adjusting the temperature and/or the pressure of the reactor such that one or more of the gas-phase reactants condense within the micropores of the catalyst thereby causing the catalytic reaction to take place in a liquid phase. Additionally, a process for engineering defects on a carboxylate-based metal organic framework (MOF) catalyst is described. The process includes providing a carboxylate-based MOF catalyst; and heating the carboxylate-based MOF catalyst in an inert gas atmosphere at temperatures between about 150° C. and about 900° C.
Syntactic foams are materials including hollow microspheres distributed throughout a cured polymeric resin. Hollow microspheres within syntactic foams, including collapsible shells that enclose empty cavities, can serve as receptacles to capture environmental constituents upon applied temperature and pressure. An epoxy formulation including of EPON™ 828, HELOXY™ 61, and TETA was combined with hollow glass microspheres with isostatic crush strengths of 300, 3000, and 10,000 psi. Effects of pressure and temperature on the mechanical properties were evaluated via dynamic mechanical analysis. Storage modulus and glass transition temperature depended on formulation. Upon exposure to specific temperature and pressures, the hollow glass spheres embedded within the resin lose mechanical integrity and collapse, resulting in the generation of unencapsulated void spaces, primed to capture embedded liquid. Controllable loss of mechanical integrity enables syntactic foams to serve as on-demand receptacles to retain constituents in the surrounding environment, resulting from externally triggered pressures and temperatures.
G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
C08J 9/32 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof from compositions containing microballoons, e.g. syntactic foams
Provided by the inventive concept or nanoplastic or microplastic particles, reference standard materials including nanoplastic or microplastic particles, methods of using, and methods of preparing the same. Uses of the nanoplastic and/or microplastic particles of the inventive concept include tracking of nanoplastic and/or microplastic particle dispersion/distribution in environmental and/or biological systems, as well as in organisms that are within the environment.
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/94 - Investigating contamination, e.g. dust
91.
DESIGN, FABRICATION, AND CHARACTERIZATION OF NANOPLASTICS AND MICROPLASTICS
Provided by the inventive concept or nanoplastic or microplastic particles, reference standard materials including nanoplastic or microplastic particles, methods of using, and methods of preparing the same. Uses of the nanoplastic and/or microplastic particles of the inventive concept include tracking of nanoplastic and/or microplastic particle dispersion/distribution in environmental and/or biological systems, as well as in organisms that are within the environment.
B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
C09K 11/00 - Luminescent, e.g. electroluminescent, chemiluminescent, materials
G01N 1/38 - Diluting, dispersing or mixing samples
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
A computer implemented method is disclosed for detecting a mild traumatic brain injury (mTBI) on a subject having recently suffered a head injury. The method includes (1) receiving first electrocardiogram (ECG) data from the subject during a first transition from a first position to a second position; and (2) determining a probability value of mTBI within the subject based at least partially on the first ECG data during the first transition. The first position may be a prone position or a supine position and the second position may be a standing position.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/352 - Detecting R peaks, e.g. for synchronising diagnostic apparatusEstimating R-R interval
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/0205 - Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
93.
INDAZOLE DERIVATIVES AS CANNABINOID RECEPTOR PARTIAL AGONISTS
The present disclosure includes peripheral partial agonists of one or more CB receptors, including modulation of CB1, both with and without CB2 selectivity. The compounds of the present disclosure may be useful in the treatment of diseases and disorders mediated by a CB-signaling pathway, including but not limited to pain, gastrointestinal disorders, metabolic disorders, and liver disorders, such as alcoholic steatohepatitis or nonalcoholic steatohepatitis (NASH),
A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
C07D 209/40 - Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
94.
TUNABLE DEGRADATION OF ESTER-BASED EPOXY FORMULATIONS
The present disclosure relates to delivery and release compositions, systems, and methods of use thereof. In particular, the present disclosure relates to degradable polymeric systems including a first epoxy-containing monomer and a second, different epoxy-containing monomer, wherein the degradable polymeric system is crosslinked, and wherein one of the first epoxy-containing monomer and the second, different epoxy-containing monomer includes one or more ester groups; delivery systems incorporating degradable polymeric systems; and methods for providing cargo to a petroleum reservoir.
C08G 59/18 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
C08G 59/20 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups characterised by the epoxy compounds used
A method for reducing the concentration of amines in a wash liquid stream exiting a wash section in an acid gas scmbbing process includes introducing the wash liquid stream exiting the wash section of the acid gas scrubbing process to an adsorbent material, wherein the wash liquid stream has a first concentration of amines. The wash liquid stream having the first concentration of amines is flowed through the adsorbent material, and the adsorbent material retains at least a portion of the amines thereby providing a wash liquid stream having a second, reduced concentration of amines. The wash stream with reduced concentration of amines is recycled back to the wash section to remove amines more effectively from the acid gas being scrubbed. The adsorbent material can be regenerated for reuse. Amine recovered from the regenerated adsorbent material can be recycled to the process for reuse.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
C02F 1/28 - Treatment of water, waste water, or sewage by sorption
C02F 1/58 - Treatment of water, waste water, or sewage by removing specified dissolved compounds
96.
METHODS AND SYSTEMS FOR REDUCING THE CONCENTRATION OF AMINE IN WASH LIQUID USED IN INDUSTRIAL PROCESSING
A method for reducing the concentration of amines in a wash liquid stream exiting a wash section in an acid gas scmbbing process includes introducing the wash liquid stream exiting the wash section of the acid gas scrubbing process to an adsorbent material, wherein the wash liquid stream has a first concentration of amines. The wash liquid stream having the first concentration of amines is flowed through the adsorbent material, and the adsorbent material retains at least a portion of the amines thereby providing a wash liquid stream having a second, reduced concentration of amines. The wash stream with reduced concentration of amines is recycled back to the wash section to remove amines more effectively from the acid gas being scrubbed. The adsorbent material can be regenerated for reuse. Amine recovered from the regenerated adsorbent material can be recycled to the process for reuse.
C02F 1/28 - Treatment of water, waste water, or sewage by sorption
C02F 1/58 - Treatment of water, waste water, or sewage by removing specified dissolved compounds
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
97.
TUNABLE DEGRADATION OF ESTER-BASED EPOXY FORMULATIONS
The present disclosure relates to delivery and release compositions, systems, and methods of use thereof. In particular, the present disclosure relates to degradable polymeric systems including a first epoxy-containing monomer and a second, different epoxy-containing monomer, wherein the degradable polymeric system is crosslinked, and wherein one of the first epoxy-containing monomer and the second, different epoxy-containing monomer includes one or more ester groups; delivery systems incorporating degradable polymeric systems; and methods for providing cargo to a petroleum reservoir.
C08G 59/18 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
C08G 59/20 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups characterised by the epoxy compounds used
98.
Desalting apparatus using solvent and the method thereof
Disclosed is a desalination apparatus using a solvent extraction scheme. The desalination apparatus using a solvent extraction scheme includes a source water supply module configured to supply source water including salt of a first concentration and water, a functional solvent supply module configured to supply a functional solvent, of which the solubility in water varies according to temperature, a mixing module configured to mix the source water from the source water supply module and the functional solvent from the functional solvent supply module, a first separation module configured to receive mixture water, in which the source water and the functional solvent are mixed, from the mixing module, and dissolve the water contained in the source water in the functional solvent, a salt crystallization module configured to receive the source water including salt of a second concentration that is higher than the first concentration, from which the water has been removed, from the first separation module, and a second separation module configured to receive the functional solvent, in which the water has been dissolved, from the first separation module, and thermally separate the water and the functional solvent at a second temperature that is higher than the first temperature.
A non-aqueous solvent system configured to remove acidic gas from a gas stream comprises a solution formed of a chemical absorption component and a physical absorption component. The chemical absorption component includes a nitrogenous base, wherein the nitrogenous base has a structure such that it reacts with a portion of the acidic gas. The physical absorption component includes an organic diluent that is non-reactive with the acidic gas and that has a structure such that it absorbs a portion of the acidic gas at a pressure above atmospheric pressure. The solvent system has a solubility with water of less than about 10 g of solvent per 100 mL of water.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
A chemical sensor and a system and method for sensing a chemical species. The chemical sensor includes a plurality of nanofibers whose electrical impedance varies upon exposure to the chemical species, a substrate supporting and electrically isolating the fibers, a set of electrodes connected to the plurality of fibers at spatially separated points to permit the electrical impedance of the plurality of fibers to be measured, and a membrane encasing the fibers and having a thickness ranging from 50 μm to 5.0 mm. The system includes the chemical sensor, an impedance measuring device coupled to the electrodes and configured to determine an electrical impedance of the plurality of fibers, and an analyzer configured to identify the chemical species based on a change in the electrical impedance.
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G01N 27/12 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluidInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon reaction with a fluid
G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
