Seraxis, Inc.

United States of America

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New (last 4 weeks) 1
2026 May 1
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IPC Class
A61K 35/39 - PancreasIslets of Langerhans 12
C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues 12
A61L 27/38 - Animal cells 6
A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones 6
C12N 5/074 - Adult stem cells 6
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Status
Pending 7
Registered / In Force 13

1.

PANCREATIC CELLS FOR TREATING DIABETES AND METHODS OF GENERATING THE SAME

      
Application Number 19353454
Status Pending
Filing Date 2025-10-08
First Publication Date 2026-05-14
Owner Seraxis, Inc. (USA)
Inventor Rust, William L.

Abstract

The present disclosure provides cell-based compositions for treating diabetes, methods for identifying cells that preferentially differentiate into endoderm cells, and methods for preparing insulin-producing pancreatic cells, as well as related methods of use for treating diseases related to insulin deficiency.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

2.

MODIFIED THERAPEUTICS CELLS AND METHODS RELATING TO THE SAME

      
Application Number US2024040216
Publication Number 2025/029826
Status In Force
Filing Date 2024-07-30
Publication Date 2025-02-06
Owner SERAXIS, INC. (USA)
Inventor
  • Rust, William L.
  • Ratiu, Jeremy

Abstract

The present disclosure provides a modified stem cell useful for generating cell-based compositions for treating diabetes, as well as methods for preparing such cells.

IPC Classes  ?

  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

3.

THERAPEUTIC CELLS AND METHODS RELATING TO THE SAME

      
Document Number 03281834
Status Pending
Filing Date 2024-02-02
Open to Public Date 2024-08-08
Owner SERAXIS, INC. (USA)
Inventor Rust, William L.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/074 - Adult stem cells
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

4.

THERAPEUTIC CELLS AND METHODS RELATING TO THE SAME

      
Application Number US2024014306
Publication Number 2024/163938
Status In Force
Filing Date 2024-02-02
Publication Date 2024-08-08
Owner SERAXIS, INC. (USA)
Inventor Rust, William L.

Abstract

The present disclosure provides cell-based compositions for treating diabetes, as well as methods for preparing such cells.

IPC Classes  ?

  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/074 - Adult stem cells
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

5.

PANCREATIC CELLS FOR TREATING DIABETES AND METHODS OF GENERATING THE SAME

      
Application Number 17959203
Status Pending
Filing Date 2022-10-03
First Publication Date 2023-02-02
Owner Seraxis, Inc. (USA)
Inventor Rust, William L.

Abstract

The present disclosure provides cell-based compositions for treating diabetes, methods for identifying cells that preferentially differentiate into endoderm cells, and methods for preparing insulin-producing pancreatic cells, as well as related methods of use for treating diseases related to insulin deficiency.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

6.

SERAGRAFT

      
Serial Number 97409778
Status Pending
Filing Date 2022-05-13
Owner Seraxis Inc ()
NICE Classes  ? 42 - Scientific, technological and industrial services, research and design

Goods & Services

Research and development in the pharmaceutical and biotechnology fields for the purpose of cell replacement for the treatment of diabetes; none of the foregoing related to orthopedics, orthopedic applications, bones, medical bone repair, prosthetics, skin grafts, biological tissue, and medical devices, instruments, and materials used for the repair of bones

7.

SERAXIS

      
Serial Number 97083181
Status Registered
Filing Date 2021-10-20
Registration Date 2023-01-17
Owner Seraxis Inc ()
NICE Classes  ? 42 - Scientific, technological and industrial services, research and design

Goods & Services

Research and development in the pharmaceutical and biotechnology fields

8.

Pancreatic cells for treating diabetes and methods of generating the same

      
Application Number 16968317
Grant Number 11484554
Status In Force
Filing Date 2019-02-08
First Publication Date 2021-01-14
Grant Date 2022-11-01
Owner Seraxis, Inc. (USA)
Inventor Rust, William L.

Abstract

The present disclosure provides cell-based compositions for treating diabetes, methods for identifying cells that preferentially differentiate into endoderm cells, and methods for preparing insulin-producing pancreatic cells, as well as related methods of use for treating diseases related to insulin deficiency.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

9.

MACRO-ENCAPSULATED THERAPEUTIC CELLS, DEVICES, AND METHODS OF USING THE SAME

      
Application Number US2019019980
Publication Number 2019/169089
Status In Force
Filing Date 2019-02-28
Publication Date 2019-09-06
Owner SERAXIS, INC. (USA)
Inventor Rust, William L

Abstract

Described are macro-capsules, barriers, and devices that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • A61L 27/38 - Animal cells
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61K 9/50 - Microcapsules
  • A61P 5/50 - Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
  • A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones
  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution

10.

MACRO-ENCAPSULATED THERAPEUTIC CELLS, DEVICES, AND METHODS OF USING THE SAME

      
Document Number 03092356
Status Pending
Filing Date 2019-02-28
Open to Public Date 2019-09-06
Owner SERAXIS, INC. (USA)
Inventor Rust, William L

Abstract

Described are macro-capsules, barriers, and devices that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.

IPC Classes  ?

  • A61K 9/50 - Microcapsules
  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61K 35/39 - PancreasIslets of Langerhans
  • A61L 27/38 - Animal cells
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones
  • A61P 5/50 - Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

11.

Macro-encapsulated therapeutic cells, devices, and methods of using the same

      
Application Number 16289626
Grant Number 11141508
Status In Force
Filing Date 2019-02-28
First Publication Date 2019-09-05
Grant Date 2021-10-12
Owner Seraxis, Inc. (USA)
Inventor Rust, William L

Abstract

Described are macro-capsules, barriers, and devices that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • A61L 31/08 - Materials for coatings
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61L 31/04 - Macromolecular materials
  • A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones
  • A61P 5/50 - Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
  • A61L 27/38 - Animal cells
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61K 9/50 - Microcapsules
  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution

12.

PANCREATIC CELLS FOR TREATING DIABETES AND METHODS OF GENERATING THE SAME

      
Application Number US2019017281
Publication Number 2019/157329
Status In Force
Filing Date 2019-02-08
Publication Date 2019-08-15
Owner SERAXIS, INC. (USA)
Inventor Rust, William L

Abstract

The present disclosure provides cell-based compositions for treating diabetes, methods for identifying cells that preferentially differentiate into endoderm cells, and methods for preparing insulin-producing pancreatic cells, as well as related methods of use for treating diseases related to insulin deficiency.

IPC Classes  ?

  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/074 - Adult stem cells
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

13.

PANCREATIC CELLS FOR TREATING DIABETES AND METHODS OF GENERATING THE SAME

      
Document Number 03090536
Status Pending
Filing Date 2019-02-08
Open to Public Date 2019-08-15
Owner SERAXIS, INC. (USA)
Inventor Rust, William L

Abstract

The present disclosure provides cell-based compositions for treating diabetes, methods for identifying cells that preferentially differentiate into endoderm cells, and methods for preparing insulin-producing pancreatic cells, as well as related methods of use for treating diseases related to insulin deficiency.

IPC Classes  ?

  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/074 - Adult stem cells
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

14.

MACRO-ENCAPSULATED THERAPEUTIC CELLS AND METHODS OF USING THE SAME

      
Document Number 03058369
Status Pending
Filing Date 2018-03-01
Open to Public Date 2018-10-11
Owner SERAXIS, INC. (USA)
Inventor Rust, William L.

Abstract

Described are macro-capsules and barriers that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.

IPC Classes  ?

  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/50 - Microcapsules
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • A61K 35/39 - PancreasIslets of Langerhans
  • A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
  • A61L 27/20 - Polysaccharides
  • A61L 27/38 - Animal cells
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones

15.

Macro-encapsulated therapeutic cells and methods of using the same

      
Application Number 15909449
Grant Number 11975031
Status In Force
Filing Date 2018-03-01
First Publication Date 2018-10-11
Grant Date 2024-05-07
Owner Seraxis, Inc. (USA)
Inventor Rust, William L.

Abstract

Described are macro-capsules and barriers that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/50 - Microcapsules
  • A61L 27/20 - Polysaccharides
  • A61L 27/38 - Animal cells
  • A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones
  • A61P 5/50 - Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells

16.

MACRO-ENCAPSULATED THERAPEUTIC CELLS AND METHODS OF USING THE SAME

      
Application Number US2018020446
Publication Number 2018/186953
Status In Force
Filing Date 2018-03-01
Publication Date 2018-10-11
Owner SERAXIS, INC. (USA)
Inventor Rust, William L.

Abstract

Described are macro-capsules and barriers that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.

IPC Classes  ?

  • A61P 5/48 - Drugs for disorders of the endocrine system of the pancreatic hormones
  • A61L 27/20 - Polysaccharides
  • A61L 27/38 - Animal cells
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances

17.

Method for generating non-pluripotent progenitors of surrogate pancreatic cells

      
Application Number 14693245
Grant Number 09474772
Status In Force
Filing Date 2015-04-22
First Publication Date 2015-08-20
Grant Date 2016-10-25
Owner Seraxis, Inc. (USA)
Inventor Rust, William L.

Abstract

Fresh human pancreas tissue can be used as a source of cells whence to identify and select a non-stem cell population that is predisposed to be a source for surrogate pancreatic cells that can be used in treating insulin-dependent diabetes. The progenitors of these surrogate pancreatic cells have no reprogramming genes integrated into their genomes, differentiate to the pancreatic lineage pursuant to a protocol that employs only defined reagents, and are substantially unable to differentiate to the mesodermal lineage.

IPC Classes  ?

  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

18.

STEM CELLS AND PANCREATIC CELLS USEFUL FOR THE TREATMENT OF INSULIN-DEPENDENT DIABETES MELLITUS

      
Document Number 02876677
Status In Force
Filing Date 2013-06-24
Open to Public Date 2014-01-03
Grant Date 2021-09-07
Owner SERAXIS, INC. (USA)
Inventor Rust, William L.

Abstract

Fresh human pancreas tissue can be used as a source of cells whence to identify and select a non-stem cell population that is predisposed to be a source for surrogate pancreatic cells that can be used in treating insulin-dependent diabetes. The progenitors of these surrogate pancreatic cells have no reprogramming genes integrated into their genomes, differentiate to the pancreatic lineage pursuant to a protocol that employs only defined reagents, and are substantially unable to differentiate to the mesodermal lineage.

IPC Classes  ?

  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/074 - Adult stem cells

19.

STEM CELLS AND PANCREATIC CELLS USEFUL FOR THE TREATMENT OF INSULIN-DEPENDENT DIABETES MELLITUS

      
Application Number US2013047243
Publication Number 2014/004341
Status In Force
Filing Date 2013-06-24
Publication Date 2014-01-03
Owner SERAXIS, INC. (USA)
Inventor Rust, William, L.

Abstract

Fresh human pancreas tissue can be used as a source of cells whence to identify and select a non-stem cell population that is predisposed to be a source for surrogate pancreatic cells that can be used in treating insulin-dependent diabetes. The progenitors of these surrogate pancreatic cells have no reprogramming genes integrated into their genomes, differentiate to the pancreatic lineage pursuant to a protocol that employs only defined reagents, and are substantially unable to differentiate to the mesodermal lineage.

IPC Classes  ?

  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/074 - Adult stem cells

20.

Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus

      
Application Number 13925248
Grant Number 09968639
Status In Force
Filing Date 2013-06-24
First Publication Date 2013-12-26
Grant Date 2018-05-15
Owner Seraxis, Inc. (USA)
Inventor Rust, William L.

Abstract

Fresh human pancreas tissue can be used as a source of cells when to identify and select a non-stem cell population that is predisposed to be a source for surrogate pancreatic cells that can be used in treating insulin-dependent diabetes. The progenitors of these surrogate pancreatic cells have no reprogramming genes integrated into their genomes, differentiate to the pancreatic lineage pursuant to a protocol that employs only defined reagents, and are substantially unable to differentiate to the mesodermal lineage.

IPC Classes  ?

  • A61K 35/39 - PancreasIslets of Langerhans
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues