Thrombectomy systems and methods are provided for acquiring a baseline pulmonary artery pressure and a baseline change in the pulmonary artery pressure over time, deriving a baseline hemodynamics assessment of the subject from one or more characteristics of a relationship between the acquired baseline pulmonary artery pressure and the baseline change in pulmonary artery pressure over time, removing at least one occlusion or partial occlusion in the pulmonary artery branch, after removing the at least one occlusion or partial occlusion, acquiring a post-treatment pulmonary artery pressure and a post-treatment change in the pulmonary artery pressure over time, deriving a post-treatment hemodynamics assessment from one or more characteristics of a relationship between the acquired post-treatment pulmonary artery pressure and the post-treatment change in pulmonary artery pressure over time, and providing a signal indicative of a treatment completion state based a correlation between the baseline hemodynamics assessment and the post-treatment hemodynamics assessment.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
Intravascular blood pumps systems and methods of use are provided. The blood pump system comprises an expandable shroud forming a blood conduit. The shroud comprises a distal section, a proximal impeller section, and a central section between the distal section and the proximal impeller section. The central section comprises a helical pattern in which at least one of a pitch angle or a strut thickness varies along a transitional portion of the central section.
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
3.
SHAPE MEMORY ACTUATORS FOR ADJUSTABLE SHUNTING SYSTEMS, AND ASSOCIATED SYSTEMS AND METHODS
The present technology is directed to adjustable shunting systems having a shunting element, a shape memory actuator, and a lumen extending therethrough for transporting fluid. The shape memory actuator can have a plurality of struts proximate the shunting element and a plurality of projections extending from the plurality of struts. In operation, the shape memory actuator can be used to adjust a geometry of the lumen. In some embodiments, the system is configured such that (a) any strain in the shape memory actuator is concentrated in the struts, and/or (b) the struts experience greater resistive heating than the projections when an electrical current is applied to the actuator.
A61M 27/00 - Drainage appliances for wounds, or the like
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
4.
MULTI-PIECE ACCOMMODATING INTRAOCULAR LENSES AND METHODS FOR MAKING AND USING SAME
An accommodating intraocular lens (AIOL) for implantation within a capsular bag of a patient's eye comprises first and second components coupled together to define an inner fluid chamber and an outer fluid reservoir. The inner region of the AIOL provides optical power with one or more of the shaped fluid within the inner fluid chamber or the shape of the first or second components. The fluid reservoir comprises a bellows region with fold(s) extending circumferentially around an optical axis of the eye. The bellows engages the lens capsule, and a compliant fold region between the inner and outer bellows portions allows the profile of the AIOL to deflect when the eye accommodates for near vision. Fluid transfers between the inner fluid chamber and the outer fluid reservoir to provide optical power changes. A third lens component coupled to the first or second component provides additional optical power.
Thrombectomy systems and methods are provided for acquiring a baseline pulmonary artery pressure and a baseline change in the pulmonary artery pressure over time, deriving a baseline hemodynamics assessment of the subject from one or more characteristics of a relationship between the acquired baseline pulmonary artery pressure and the baseline change in pulmonary artery pressure over time, removing at least one occlusion or partial occlusion in the pulmonary artery branch, after removing the at least one occlusion or partial occlusion, acquiring a post-treatment pulmonary artery pressure and a post-treatment change in the pulmonary artery pressure over time, deriving a post-treatment hemodynamics assessment from one or more characteristics of a relationship between the acquired post-treatment pulmonary artery pressure and the post-treatment change in pulmonary artery pressure over time, and providing a signal indicative of a treatment completion state based a correlation between the baseline hemodynamics assessment and the post-treatment hemodynamics assessment.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/295 - Balloon pumps for circulatory assistance
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/808 - Vanes or blades specially adapted for deformable impellers, e.g. expandable impellers
Devices for moving blood within a patient, and methods of doing so. The devices can include a pump portion that includes an impeller and a housing around the impeller, as well as a fluid lumen. The impeller can be activated to cause rotation of the impeller and thereby move fluid within the fluid lumen.
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A device for treating a diseased native valve in a patient is provided, which can include a frame structure comprising an inflow region having an inflow end, an outflow region having an outflow end, and a central waist portion positioned between the inflow region and the outflow region, a valve segment positioned radially within the frame structure, the valve segment comprising a plurality of leaflets, and an internal skirt coupled to an interior of the frame structure and to the valve segment and extending from the inflow region to the outflow region, wherein the internal skirt includes a plurality of leaflet tabs coupled to the plurality of leaflets, wherein an inflow edge of each of the plurality of leaflets is supported only by a corresponding leaflet tab. The device can also include an external skirt coupled to an exterior of the frame structure.
Catheter blood pumps that include an expandable blood conduit and at least one impeller. Tension members extending from the blood conduit are associated with increasing a stiffness of an impeller region housing the impeller, thereby increasing the impeller region's resistance to deflection, and maintaining clearance for the impeller. In some cases, a tension control element is used to control a degree of tension placed on the tension members. The tension control element may be used to increase or decrease the stiffness of the impeller region and/or modulate the size of a blood inlet or outlet of the blood conduit.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/408 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
The present technology is generally directed to adjustable shunting systems, including adjustable shunting systems having at least two discrete fluid flow paths having different fluid resistances. In at least some embodiments, the shunting systems include an actuator that controls which of the two discrete fluid flow paths is “open” to fluid flow. For example, the actuator can be configured to selectively control the flow of fluid through the system by selectively alternating between (i) opening a first flow path while closing a second flow path, and (ii) opening the second flow path while closing the first flow path.
Intravascular blood pumps systems and methods of use. The blood pump system includes a catheter portion having a distal blood pump with one or more distal collapsible impellers. The system can include a clean purge fluid pathway to carry clean fluid distally to the blood pump and a purge fluid return pathway to carry return fluid proximally into an external motor and out a proximal end of the motor, and optionally to a waste reservoir.
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/90 - Details not provided for in groups , or
13.
SYSTEMS AND METHODS FOR SELECTIVELY ADJUSTING AND/OR CALIBRATING IMPLANTABLE SHUNTING SYSTEMS
The present technology generally relates to implantable medical devices and, in particular, to systems and methods for selectively adjusting and/or calibrating implantable shunting systems, including opening and/or closing the shunting systems after implantation within a patient. In some embodiments, a system for selectively adjusting and/or calibrating an implantable shunting system includes an energy transmission device configured to be positioned at least proximate to the implantable shunting system. The energy transmission device can be configured to transmit energy to the adjustable shunting element to change a dimension of the adjustable shunting element. In at least some embodiments, for example, the adjustable shunting element can define a lumen having a diameter, and the energy transmitted by the energy transmission device can cause a decrease to the diameter of the lumen.
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
The present technology provides implantable medical devices and systems and methods for percutaneously delivering the same. In some embodiments, the present technology includes a pusher catheter assembly configured to provide pushing forces against an implantable medical device collapsed within a delivery sheath to push the device out of the sheath and deploy the device at a target anatomical location. The pusher catheter assembly can include one or more device engagement component that are designed to provide pushing forces against the device when the device is positioned within the sheath. The device engagement component can be sized and shaped to bypass one or more first components of the device positioned proximally within the sheath such that the pusher catheter assembly provides pushing forces against one or more second components of the device that are positioned distally within the sheath.
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
A61F 2/962 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
15.
CARDIAC VALVE PROSTHESIS DELIVERY SYSTEM AND METHODS OF USE
Delivery systems, devices, and methods for delivering a valve prosthesis to a native valve annulus are provided. The valve prosthesis may be secured to the native valve via an anchor that encircles the native valve annulus and the valve prosthesis. The anchor may be deployed around the chordae tendinea and/or leaflets of the native valve. A tether may be connected to the anchor and extend outside of the patient's body to maintain communication with the anchor. After the anchor is deployed, a guidewire may be advanced through the patient's vessels parallel to the tether and through the native valve annulus. A valve delivery catheter carrying the valve prosthesis may be advanced over the guidewire and into the native valve annulus where the valve prosthesis is released and deployed. The tether may be used to position the anchor and/or valve prosthesis during one or more operations of the valve delivery process.
Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A61M 60/816 - Sensors arranged on or in the housing, e.g. ultrasound flow sensors
E02D 5/18 - Bulkheads or similar walls made solely of concrete in situ
E02D 5/68 - Mould-pipes or other moulds for making bulkheads
An accommodating intraocular lens (AIOL) for implantation within a capsular bag of a patient's eye comprises first and second components coupled together to define an inner fluid chamber and an outer fluid reservoir. The inner region of the AIOL provides optical power with one or more of the shaped fluid within the inner fluid chamber or the shape of the first or second components. The fluid reservoir comprises a bellows region with fold(s) extending circumferentially around an optical axis of the eye. The bellows engages the lens capsule, and a compliant fold region between inner and outer bellows portions allows the profile of the AIOL to deflect when the eye accommodates for near vision. Fluid transfers between the inner fluid chamber and the outer fluid reservoir to provide optical power changes. A third lens component coupled to the first or second component provides additional optical power.
A cartridge for use with an accommodating intraocular lens (AIOL) assembly comprising an anterior portion, a posterior portion connected to the anterior portion at a seam, an interior chamber between the anterior portion and the posterior portion, and/or a plurality of tabs extending radially outward from one or both of the anterior portion and the posterior portion.
The present technology provides shunting systems that include an anchoring feature, a first canister, a second canister, and a tethering element coupling the first canister to the second canister. The tethering element can (a) orient the first canister and the second canister in a predetermined configuration when the system is deployed from a catheter, and (b) retain the first canister and the second canister in the predetermined configuration following deployment of the system.
The present technology is generally directed to an adjustable shunting system for draining fluid from a first body region to a second body region. The adjustable shunting system can include a screen assembly configured to at least partially prevent debris from entering an internal portion of the adjustable shunting system. For example, the screen can be at least partially aligned with one or more fluid inlets of the adjustable shunting system. In some embodiments, the adjustable shunting system include one or more actuators that can be actuated via energy. In such embodiments, the screen assembly can be configured such that the actuators are accessible to energy through the screen. In these and other embodiments, the screen can be at least partially cleaned of debris by applying non-invasive ablative energy to the screen.
Devices and systems for treatment of a diseased heart valve. The anchor may be deployed around chordae and/or leaflets of the diseased valve prior to delivery of a valve prosthesis into the annulus of the diseased valve and within the anchor. A tether may be configured to provide access to the anchor and/or adjust a position of the anchor with respect to the diseased valve. The tether may include a proximal region and a distal region, where the distal region may be releasably connectable to the anchor. The proximal and distal regions may have different properties, such as different flexibilities. In some cases, at least a portion of the tether may be configured to transition between a flexible and stiff state.
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A delivery system for delivering a spiral anchor to a diseased native valve of a heart includes an anchor control catheter and an anchor guide extending from the anchor control catheter. The anchor guide includes a flexible configuration and a rigid configuration. The anchor guide in the rigid configuration includes a proximal section, a middle section, and a distal section. The proximal section includes a straight central axis and extends from the anchor control catheter, the middle section spirals axially and radially outwards from the central axis, and the distal section curves concentrically about the central axis in a plane that is perpendicular to the central axis.
Systems and methods for automated transesophageal echocardiogram control and sensor analysis. An example method includes controlling the TEE tool within the esophagus to be at a plurality of station coordinates, wherein the station coordinates reflect unique combinations of values of degrees of freedom of the TEE tool; analyzing, using a classifier and/or regression model, sensor information obtained from the TEE tool while at the station coordinates; and determining a subset of the station coordinates which are associated with respective cardiac views, wherein station coordinates associated with a cardiac view indicates that sensor information obtained from the TEE tool at the station coordinates depicts the cardiac view.
The present technology is generally directed to adjustable shunting systems for draining fluid from a first body region to a second body region. The adjustable shunting systems include an actuation assembly having one or more actuators for controlling the flow of fluid through the system. Each of the actuators can be actuated via energy. The adjustable shunting systems can further one or more energy redirecting elements. Each of the energy redirecting elements can redirect or transmit the received energy to a corresponding actuator. Accordingly, each of the actuators can be independently actuated by applying energy to the corresponding redirecting element.
Catheter blood pump positioning techniques, methods, and algorithms are described. In one embodiment, pressure sensor measurements are used to determine the distance to the aortic valve and the left ventricle. An optimal positioning location can be determined based on the pressure sensor measurements. The catheter blood pump can then be optimally positioned to locate the inlet in the ventricle and the outlet in the aorta.
27.
PROSTHETIC CARDIAC VALVE DELIVERY DEVICES, SYSTEMS, AND METHODS
A device and system for use with medical devices, such as catheter devices or systems. The device or system comprises an anchor for securing to tissue. In some examples, the device or system is used in treating a diseased native valve in a patient. The anchor may be part of a delivery device to implant a prosthetic valve. Subsequent to delivery, the components of the delivery device are actuated to secure the prosthetic valve within the diseased valve.
Catheter blood pump positioning techniques, methods, and algorithms are described. In one embodiment, pressure sensor measurements are used to determine the distance to the aortic valve and the left ventricle. An optimal positioning location can be determined based on the pressure sensor measurements. The catheter blood pump can then be optimally positioned to locate the inlet in the ventricle and the outlet in the aorta.
A61M 60/816 - Sensors arranged on or in the housing, e.g. ultrasound flow sensors
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/226 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
A61M 60/554 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
A61M 99/00 - Subject matter not provided for in other groups of this subclass
29.
LASER-ADJUSTABLE SHUNTS AND ASSOCIATED SYSTEMS AND METHODS
The present technology is generally directed to adjustable shunts with actuation assemblies that are configured to be selectively adjusted using laser energy to change a fluid resistance through the shunt. The actuation assemblies include features expected to improve the performance of laser-adjustable shunts, such as by improving the safety profile of laser-adjustable shunts and/or by improving the efficiency of operating laser-adjustable shunts.
A heart valve prosthesis for replacing a diseased native valve in a patient, the valve includes a compressible and expandable frame structure and an anchor connected to an outer periphery of the frame structure. The anchor comprises a free end and has a flat spiral shape. The valve may further include a valve segment mounted within the frame structure and expanded with the frame structure. The frame structure may be configured for receiving a valve segment.
The present technology relates to pulsed field ablation (PFA) and associated systems and methods. Embodiments of the present disclosure include a PFA system that is delivered via a low-profile catheter. The PFA catheter is formed to provide a flexible, adaptive ablation tool under robotic control for targeted and precise delivery of energy to selected tissue regions. This enables enhanced tissue targeting and continuity of generated lesions. The ablation may be delivered by selected pairs of electrodes via, for example, electric pulses.
A system for delivering energy to implanted devices using electromagnetic wireless charging and associated systems and methods are disclosed herein. In some embodiments, the system includes an energy transmission device and an implanted device. The energy transmission device can include multiple transmission coils, while the implanted device can include one or more receiving coils and one or more chargeable energy storage components. The transmission coils on the energy transmission device can each be energized to generate an electromagnetic field. When the implanted device is positioned within range of the energy transmission device, the receiving coils in the implanted device interact with the electromagnetic fields to generate a current. The current is used to charge the energy storage components.
The present technology is generally directed to adjustable shunting systems for draining fluid from a first body region to a second body region. The adjustable shunting systems include a flow control plate or cartridge for controlling the flow of fluid through the system. For example, the flow control plate can include a shape memory actuation assembly having one or more nitinol actuators for controlling the flow of fluid through the system. The flow control plate can further include a plurality of discrete sheets or layers adhered together to encase the shape memory actuation assembly. The discrete sheets or layers can form flow channels for directing fluid through the flow control plate.
Prosthetic heart valves and delivery systems and methods of delivery and use are provided herein. The heart valve can include a valve frame with a flared atrial portion, a flared ventricular portion, and a narrowed central waist portion between the flared atrial and ventricular portions. The system can further include a helical anchoring device configured to retain the valve frame within the native mitral valve anatomy. The valve frame and anchoring device are configured to dynamically expand, and contract once implanted in response to the dynamic heart cycle. When the anchor and frame are in an at-rest state in which low heart pressures are applied against the system, the anchor applies very low retaining forces against the frame. When heart pressures increase and cause axial movement of the frame relative to the anchor, the retaining forces applied by the anchoring device to the frame increase.
The present technology relates to accommodating intraocular lenses (AIOLs) and methods of manufacturing the same. In many of the embodiments disclosed herein, the AIOLs include an adjustable lens structure and a fixed lens configured to be removably coupled to the accommodating lens structure. The adjustable lens structure can include a base defining an adjustable lens and a lens-receiving area configured to receive the fixed lens. The adjustable lens can have a dynamically adjustable range of optical powers and/or depths of field. The fixed lens can have a fixed optical power and/or depth of field. The base of the AIOL can be a unitary body formed using, e.g., rotational molding.
The present technology is directed to implantable medical devices including one or more communication elements configured to transmit and/or receive communication signals. The one or more communication elements can be coupled to one or more components of the device. The communication signals can be used to control, transmit, and/or to receive information from one or more of the components. The communication element(s) can additionally be coupled to a power source and used to transfer power to the components, and/or to transfer operational signals from a first component to a second component. The communication element(s) can be configured to perform a first function at a first (e.g., high) frequency or frequency range, and to perform a second function at a second (e.g., low) frequency or frequency range.
The present technology is generally directed to shunting systems, including shunting systems having a shapeable/conformable elongated housing or shunting element that can be contoured or otherwise selectively shaped to improve a fit with patient anatomy. The shunting systems and elongated housings described herein can have numerous other advantageous features expected to improve the operation of shunting systems, such as beveled leading edges, lateral outlets, suture rings, positioning appendages, and the like.
The present technology is generally directed to adjustable shunting systems for draining fluid from a first body region to a second body region. The adjustable shunting systems include an actuation assembly for controlling the flow of fluid through the system. For example, the actuation assembly can include one or more fluid inlets in fluid communication with an environment external to the system. The actuation assembly can further include one or more actuators configured to move a corresponding control element to control the flow of fluid through the fluid inlets. The actuator can also have a first actuation element and a second actuation element configured to move the control element between a first position in which the control element substantially prevents fluid flow through the corresponding inlet and a second position in which the control element does not substantially prevent fluid flow through the fluid inlets.
The present technology is generally directed to medical systems having sensors and diaphragms. The sensor device can include a body having a diaphragm. The diaphragm can be formed, for example, by applying a force to the body to create an impression or pattern that corresponds to the diaphragm. The sensor device can be positioned at least partially within a body cavity, and the diaphragm can be configured to flex or bend in response to one or more physiological parameters in the body cavity. In some embodiments, the sensor device can include one or more sensor measurement components configured to measure the one or more physiological parameters based on the flexing or bending of the diaphragm.
An accommodating intraocular lens (AIOL) can include a fixed power lens and a base. The base can include an adjustable power lens and define a lens-receiving area configured to receive the fixed power lens. A change to the fixed power lens can cause an adjustment to an optical power of the adjustable power lens. In some embodiments, the fixed power lens can be rotated within the lens-receiving area relative to the base to cause the adjustment to the optical power. Additionally, or alternatively, the fixed power lens can be replaced with a second non-accommodating or other lens to cause the adjustment to the optical power. The second fixed power lens can have one or more dimensions that are greater or less than corresponding dimensions of the fixed power lens.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
41.
SYSTEMS AND METHODS FOR DELIVERING AND DEPLOYING ADJUSTABLE SHUNTING SYSTEMS
The present technology is generally directed to shunt delivery systems and associated methods for delivering and deploying adjustable shunts. In some embodiments, the delivery systems include a housing, a pair of movement guides positioned within the housing, and an actuation assembly positioned at least partially between the pair of movement guides. The actuation assembly can include an actuator and a pair of arms operably engaged by the actuator. The actuation assembly can be configured to releasably carry a shunt at least partially between the pair of arms. The actuator can be movable relative to the pair of movement guides to cause movement of the pair of arms relative to the housing to, e.g., expose a length of the shunt distally beyond the arms.
The present technology is generally directed to shunting systems having visual system state indicators and/or flow indicators. The system state indicators assist a user in determining a state of the shunt, such as whether a shunt lumen is set to an open or closed position. The flow indicators assist a user in determining whether fluid is flowing through the shunt lumen.
The present technology includes implantable medical devices having a first disc-shaped anchoring portion and a second disc-shaped anchoring portion connected to the first disc-shaped anchoring portion by an intermediate neck region. The first and second disc-shaped anchoring portions can be formed by one or more filaments woven or formed in a mesh-like pattern. The filaments can be configured such that the first and second disc-shaped anchoring portions have three-dimensional bodies having a partially enclosed cavity or chamber. The device can further include one or more canisters positioned within and retained by the partially enclosed chamber. The canisters can house one or more components of the device, such as an energy storage component, a sensor, or other electronics.
Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The pump portion may also include a blood mover that is adapted to move blood to reduce stagnation, and is separate from the impeller.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
The present technology relates to systems and methods for delivering a dilator sheath to a target location within a patient. The dilator sheath can include a guidewire lumen configured to receive a guidewire. Embodiments are provided in which an interference fit between the guidewire and the guidewire lumen facilitate steering of the dilator sheath in at least one direction. Methods of delivering the dilator sheath are provided. Methods of delivering a medical device with the dilator sheath are also provided.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 17/00 - Surgical instruments, devices or methods
47.
ADJUSTABLE IMPLANTABLE DEVICES AND ASSOCIATED METHODS
The present technology includes systems and methods for invasively adjusting implantable devices for selectively controlling fluid flow between a first body region and a second body region of a patient. For example, in many of the embodiments described herein, a catheter can be used to mechanically and/or electrically engage an implanted medical device. Once the catheter engages the medical device, the catheter can (i) increase a dimension associated with the medical device, such as through mechanical expansion forces, and/or (ii) decrease a dimension associated with the medical device, such as by heating a shape memory component of the medical device above a phase transition temperature.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
A61M 27/00 - Drainage appliances for wounds, or the like
Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold and/or an elongate member extending proximally from the pump portion may include portions of differing radial stiffness or flexibility.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
The present technology generally relates to delivery systems for implantable shunting systems, and associated devices and methods. In some embodiments, an interatrial shunt delivery system can include a catheter and a deflection assembly. The catheter can define a lumen configured to carry an interatrial shunt. The deflection assembly can be configured to bend and thereby cause the catheter to bend. During a procedure, the interatrial shunt delivery system can be advanced into a right atrium of a patient. The deflection assembly can be used to set a curvature of at least a portion of the catheter, for example, by causing the catheter to bend. With the curvature set, the interatrial shunt delivery system can then be advanced toward and/or at least partially through a septal wall of the patient while maintaining the curvature of at least the portion of the catheter.
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to (1) at least partially fragment the thrombus and (2) provide an optical path for the imaging element, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 17/00 - Surgical instruments, devices or methods
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
51.
SYSTEMS AND METHODS FOR SELECTIVELY ADJUSTING IMPLANTABLE SHUNTING SYSTEMS
The present technology generally relates to implantable medical devices and, in particular, to systems and methods for selectively adjusting implantable shunting systems, including fully closing the shunting systems after implantation within a patient. For example, many embodiments of the present technology are directed to systems and method for plugging or sealing a lumen in an adjustable shunting element configured to fluidly couple a first body region and a second body region. At least some embodiments of the systems and methods for selectively closing interatrial shunting systems include closure devices configured to be removable, such that the closure device can be removably coupled to the implantable shunting system to at least partially or fully prevent fluid flow therethrough for a time, and can be removed from the implantable shunting system to allow fluid flow through the implantable shunting system to resume.
The present technology provides adjustable shunting systems with actuation assemblies that can be selectively adjusted to change a level of therapy provided by the shunt. The actuation assemblies can include a shape memory actuator having a plurality of leaflets or projections forming a conical shape with openings on both ends of the cone. The actuation assemblies can further include one or more membranes that individually jacket or cover individual projections of the plurality of projections to form a lumen extending through the conical shape.
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
53.
ACCOMMODATING INTRAOCULAR LENSES AND ASSOCIATED METHODS
An accommodating intraocular lens (AIOL) can include a base lens and a removable lens. The base lens can include an accommodating lens, an optical axis passing through the accommodating lens a haptic portion positioned radially-outward from the accommodating lens, a cavity formed in the haptic portion and extending radially-outward with respect to the optical axis, and/or a visual marker positioned anterior to the cavity. The removable lens can be configured to removably couple with the base lens and have a lens portion and a tab extending radially-outward from the lens portion and configured to extend at least partially into the cavity when the removable lens is coupled to the base lens. In some embodiments, at least a portion of the tab is positioned posterior to and at least partially hidden from view from an anterior-posterior perspective when the removable lens is coupled to the base lens.
Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
Intravascular blood pumps and methods of use. The blood pump include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion includes a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.
A61M 60/117 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 60/109 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems
A61M 60/126 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/279 - Peristaltic pumps, e.g. roller pumps
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
The present technology is directed to adjustable shunting systems for draining fluid from a first body region to a second body region, and can include a shunting element, an aperture in the shunting element, and an actuator for selectively controlling the flow of fluid through the aperture. The actuator can include a gating element moveable between a first position in which it does not substantially interfere with fluid flow through the aperture and a second position in which it at least partially blocks fluid flow through the aperture, and a shape memory actuation element configured to move the gating element from the first position to and/or toward the second position when actuated. The system can further include a friction element configured to frictionally engage the gating element to releasably retain the gating element at and/or proximate the second position following actuation of the shape memory actuation element.
The present technology is generally directed to implantable medical devices and associated methods. For example, a system configured in accordance with embodiments of the present technology can include a body implantable into a patient and configured to undergo a shape change, the body having a conductive path with variable conductivity in portions thereof for selective and/or preferential heating. The body can be coupled with an energy source that can delivery energy to the body and/or conductive path, to promote the shape change in the body.
A61M 27/00 - Drainage appliances for wounds, or the like
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
58.
ADJUSTABLE SHUNTING SYSTEMS AND METHODS OF MANUFACTURING THE SAME
The present technology is generally directed to adjustable shunting systems for controlling fluid flow between a first body region and a second body region. The shunting systems can include multiple components that can be separately manufactured and coupled together to form each individual system. For example, the systems can include an actuator assembly, a control assembly, and a fluidics assembly.
Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold and/or an elongate member extending proximally from the pump portion may include portions of differing radial stiffness or flexibility.
A61M 60/808 - Vanes or blades specially adapted for deformable impellers, e.g. expandable impellers
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/825 - Contact bearings, e.g. ball-and-cup or pivot bearings
The present technology is directed to measuring, estimating, or otherwise determining extravascular lung water (EVLW) in a patient. The systems can include a first device configured to be implanted in the patient and a second device configured to remain external to the patient. The first device can transmit electromagnetic energy, receive electromagnetic energy, or both transmit and receive electromagnetic energy. Likewise, the second device can receive electromagnetic energy, transmit electromagnetic energy, or both receive and transmit electromagnetic energy. In operation, an electromagnetic energy transmission pathway between the first device and the second device can include the patient's lungs. Accordingly, the system can determine EVLW in the patient based at least in part on an attenuation or phase shift of electromagnetic energy transmitted between the first device and the second device along the transmission path.
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
62.
ADJUSTABLE SHUNTS WITH IMPROVED FLOW CONTROL AND ASSOCIATED SYSTEMS AND METHODS
The present technology is generally directed to adjustable shunting systems, including adjustable shunting systems with improved flow control. For example, the adjustable shunting systems described herein can include an aperture formed within a flexible membrane extending over a well or other empty space. The flexible membrane can at least partially flex into the well or empty space to improve a seal at the aperture.
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus. The system can include mechanical engagement features for manipulating and/or urging clot material into an aspiration lumen of the catheter
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
The present technology is generally directed to shunt delivery systems and associated methods for delivering and deploying adjustable shunts. In some embodiments, the delivery systems include a first arm and a second arm configured to be coupled to and movable relative to one another, and a locking mechanism operably coupled to the first arm and configured to releasably engage the second arm to at least partially prevent movement of one or both of the first arm and the second arm relative to one another. During an adjustable shunt implantation procedure, a user can actuate the locking mechanism to at least partially prevent movement of one or both of the first arm and the second arm relative to one another, receive the adjustable shunt at the implant delivery system, and position the adjustable shunt at a target location within the patient.
Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold may include portions of differing radial stiffness based on location of the one or more impellers therein.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/408 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 17/00 - Surgical instruments, devices or methods
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
68.
SHAPE MEMORY ACTUATORS FOR ADJUSTABLE SHUNTING SYSTEMS, AND ASSOCIATED SYSTEMS AND METHODS
The present technology is generally directed to systems and methods for transporting fluid from a first body region to a second body region, and in particular to shape memory actuators for adjustable shunting systems. The shape memory actuators can have a hysteresis temperature window that surrounds body temperature. For example, the shape memory actuator can be composed at least in part of Nitinol or a Nitinol alloy and have a low-temperature-phase finish-transformation-temperature (e.g., Mf) that is less than body temperature and a high-temperature-phase finish-transformation-temperature (e.g., Af) that is greater than body temperature.
An intravascular fluid movement device that includes an expandable member having a collapsed, delivery configuration and an expanded, deployed configuration, the expandable member having a proximal end and a distal end, a rotatable member disposed radially and axially within the expandable member, and a conduit coupled to the expandable member, the conduit at least partially defining a blood flow lumen between a distal end of the conduit and a proximal end of the conduit, the conduit disposed solely radially inside of the expandable member in a distal section of the expandable member.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/295 - Balloon pumps for circulatory assistance
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
The present technology is directed to adjustable shunts for treating glaucoma. In particular, some embodiments provide shunts having a plurality of individually actuatable flow control elements that can control the flow of fluid through associated ports and/or flow lumens. For example, each individually actuatable flow control element can be actuated to modify a flow of a corresponding port and/or flow lumen. The individually actuatable flow control elements may be actuated along a given actuation axis. A flow control assembly may include a plurality of flow control elements arranged about a collection region. Accordingly, the shunts described herein can be manipulated into a variety of configurations that provide different drainage rates based on a degree to which the ports and/or flow lumens are blocked or unblocked, therefore providing a titratable glaucoma therapy for draining aqueous from the anterior chamber of the eye.
Embodiment of a delivery system and method for a prosthetic heart valve are provided herein. The system comprises a valve capsule shaped and size to contain a valve frame in a compressed configuration; a capsule shaft catheter connected to the valve capsule and extending proximally from the valve capsule; and a valve retainer removably connected to the valve frame. The system further comprises one or more elongate, flexible members connected to at least two points at or near a proximal end of the prosthetic heart valve, the elongate flexible member extending from the valve proximal end towards the capsule shaft catheter and configured to apply tension to the valve proximal end. A proximal controller at a proximal end of the capsule shaft catheter can be configured to remove the capsule from the valve frame, thereby permitting the valve frame to expand.
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus. The system can include a rib structure for manipulating and/or urging clot material into an aspiration lumen of the catheter. The rib structure may be controlled by a clinician through a handle outside the body.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
73.
CATHETER BLOOD PUMPS WITH COLLAPSIBLE PUMP HOUSING AND SENSOR SYSTEM
Catheter blood pumps that include a sensor system. The pumps may include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pumps may also include one or more impellers. One or more sensors may be arranged with respect to inflow and outflow regions of the blood lumen, the scaffold and/or the impellers.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
Catheter blood pumps are provided that include a catheter shaft extending through a lumen of a catheter. The catheter shaft can have a proximal end and a distal end, where the distal end can be operably coupled to an intravascular impeller locatable within a vessel. A handle can comprise a sealed housing, a motor in operable communication with the catheter shaft proximal end, and a strain relief disposed at least partially in the handle and providing access for the catheter shaft to pass from an interior of the handle to an exterior of the handle. A carrier assembly is also provided for coupling the motor to the handle. Methods of use are also provided.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 17/00 - Surgical instruments, devices or methods
A61M 27/00 - Drainage appliances for wounds, or the like
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 17/221 - Calculus gripping devices in the form of loops or baskets
A61B 17/00 - Surgical instruments, devices or methods
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61B 17/221 - Calculus gripping devices in the form of loops or baskets
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
77.
CONTRAST INJECTION AND VISUALIZATION SYSTEMS AND METHODS FOR THROMBUS REMOVAL DEVICE
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.
Systems, devices, and methods for treating a diseased native valve in a patient, the system comprising a compressible and expandable frame structure and an anchor. The anchor comprises a wire having a free end and is configured to be fully advanced from an atrial side of a native valve in a patient into a ventricle of the heart and anchor the frame structure to the native valve when the frame structure is in the expanded configuration adjacent the native valve.
The present technology is generally directed to adjustable shunting systems for draining fluid from a first body region to a second body region, including adjustable shunting systems having actuation assemblies. In one embodiment, an actuation assembly includes an actuator portion, a base portion, and a folding portion extending therebetween. The actuation assembly can be transitioned between an unfolded state and a folded state in response to movement of the actuator portion relative to the base portion about the folding portion. In the folded state, the actuation assembly can be configured to control fluid through the adjustable shunting system.
An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.
The present technology relates to shunting systems and methods. In some embodiments, the present technology includes a method for monitoring a shunting element implanted in a patient and having a lumen fluidly coupling two body regions. The method can comprise applying an electrical input to a first contact region and a second contact region of the shunting element. The method can also include measuring an electrical output that results from the electrical input. The method can further include calculating, via the processor, an electrical parameter associated with the shunting element based, at least in part, on the electrical output. The electrical parameter can vary based on a size of the lumen of the shunting element. The method can determine, via the processor, the size of a portion of the lumen based, at least in part, on the electrical parameter.
The present technology provides adjustable shunting systems with shape memory actuators. The shape memory actuators can be configured to selectively control the flow of fluid through the shunting system. For example, the shape memory actuators can include an anchor element, a gating element, and first and second actuation elements that extend between the anchor element and the gating element. The first actuation element can be selectively and independently actuated to rotate, pivot, or otherwise move the gating element in a first direction. The second actuation element can also be selectively and independently actuated to rotate, pivot, or otherwise move the gating element in a second direction opposite the first direction. When the shape memory actuator is coupled to the shunting system, the gating element can be positioned to moveably interface with a port or channel that permits fluid to flow into and/or through the shunting system.
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
Implants and methods for treating diseased heart valves. The implants may include a support member configured for placement near the diseased valve and an anchoring system coupled to the support member. The support member may be used to treat regurgitation and/or support a valve replacement therein. The support member may have an annular shape with an opening configured to generally align with an opening of the diseased valve. In some examples, the support member includes a coaptation structure configured to seal with the native leaflets. The anchoring system may include one or more tethers anchored to tissue of a ventricle, such as a ventricle wall and/or a papillary muscle. In some examples, sufficient tension is applied on the tethers to stabilize or reduce ventricle dilation.
A method for treating a diseased native valve in a patient includes 5 advancing a distal end of a delivery device to a first side of a native valve, deploying an anchor from a delivery configuration to a deployed configuration on the first side of the native valve, and rotating the distal end of the delivery device so as to simultaneously extend the anchor in the deployed configuration through the native valve from the first side to a second side of the native valve and 10 rotate the anchor in the deployed configuration around native chordae.
Intravascular blood pumps and methods of use. The fluid system can be configured to pump fluid to a sheath portion and a catheter portion of a catheter blood pump. The fluid system can include a console having one or more pumps for providing fluid flow to the catheter blood pump. A return waste line may return from the catheter blood pump. A removable fluid cassette that directs fluid flow may be coupled to the console. The blood pump may include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion may include a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.
A61M 60/405 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes a method for monitoring a shunting element implanted in a patient and having a lumen fluidly coupling cavities of the patient's heart. The method can comprise obtaining first and second radiographic images of at least two radiopaque elements associated with the lumen of the shunting element. A spatial relationship between the radiopaque elements varies according to a size of the lumen. The first radiographic image can be taken from a first viewing angle and the second radiographic image can be taken from a second viewing angle generally orthonormal to the first viewing angle. The method also includes determining the size of the lumen based, at least in part. on locations of the radiopaque elements in the first and second radiographic images.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/12 - Arrangements for detecting or locating foreign bodies
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
An intravascular blood pump having an expandable blood conduit with an unexpanded delivery diameter and an expanded deployed diameter; one or more expandable impellers disposed at least partially in the blood conduit; and an inflatable member disposed distal to the blood conduit, the inflatable member having an uninflated delivery configuration and an inflated configuration, the inflatable member having a diameter in the inflated configuration that is greater than the expanded deployed diameter of the blood conduit.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/808 - Vanes or blades specially adapted for deformable impellers, e.g. expandable impellers
90.
ANTENNA ASSEMBLIES FOR MEDICAL SYSTEMS AND ASSOCIATED SYSTEMS AND METHODS
The present technology is directed to implantable medical systems that can include a first implantable device, a second implantable device, and a communication assembly that extends between and physically couples the first device and the second device. The first device can include one or more first electronic components, and the second device can include one or more second electronic components. The communication assembly can include (a) one or more first wires that are configured to wirelessly receive data from, and/or wirelessly transmit data to, a third device positioned external to the patient, and (b) one or more second wires that are configured to conductively transfer power between the first electronic components and the second electronic components. In some embodiments, the one or more first wires have a helical configuration, and the one or more second wires have a linear configuration and extend within the one or more first wires.
Catheter blood pumps that include a collapsible blood conduit, a collapsible scaffold portion, and a bend formed in the collapsible scaffold. The collapsible blood conduit defines a blood lumen. The collapsible scaffold is adapted to provide radial support to the blood conduit. The blood pump also includes one or more impellers.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/855 - Constructional details other than related to driving of implantable pumps or pumping devices
Apparatuses and methods for delivering one or more parts of a valve prosthesis into a patient's heart. The apparatuses may include one or more catheters that are operationally coupled to one or more controls for controlling axial movement, rotational movement and/or deflection of the one or more catheters during the valve prosthesis delivery into the heart. The one or more controls may provide gross and fine movement control over multiple degrees of freedom of one or more catheter, thereby providing superior control for a practitioner during the valve prosthesis delivery procedure.
Catheter blood pumps that include a collapsible blood conduit, a collapsible scaffold portion, and a taper formed in the collapsible scaffold. The collapsible blood conduit defines a blood lumen. The collapsible scaffold is adapted to provide radial support to the blood conduit. The blood pump also includes one or more impellers. In some embodiments, the one or more impellers can also include a taper. The taper of the blood conduit can match the taper of the one or more impellers.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/408 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
A61M 60/808 - Vanes or blades specially adapted for deformable impellers, e.g. expandable impellers
94.
INTERFACE FOR PROSTHETIC CARDIAC VALVE AND DELIVERY SYSTEMS
Interfaces for delivery systems for delivering and deploying prosthetic heart valves. A prosthetic valve may be secured to a patient's native diseased valve by a spiral-shaped anchor that encircles an outer periphery of the prosthetic valve. In some examples, the interface provides a releasable connection between the anchor and a tether that guides placement of the anchor with respect to the patients native valve. Once the anchor is properly positioned, the prosthetic valve may be positioned and expanded within the patient's native valve and the anchor. The tether-anchor interface can release the anchor from the tether, leaving the anchor and valve prosthesis secured in place within the heart.
The present technology relates to adjustable shunting systems and methods. In some embodiments, the present technology includes an adjustable shunting system that includes a drainage element having an inflow portion configured for placement within a patient. The system can also include a flow control assembly having a gating element operably coupled to the outflow portion of the drainage element. The flow control assembly can further include a first actuation element and a second actuation element coupled to the gating element. The first and second actuation elements can be configured to selectively move the gating element relative to the outflow portion to control an amount of fluid flow therethrough. The first and second actuation elements can each extend less than entirely around a perimeter of the drainage element.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
The present technology is generally directed to shunting systems having shape memory actuation elements that can selectively change a geometry of a shunting element to affect the flow of fluid therethrough. In some embodiments, the shape memory actuation elements are incorporated as part of an onboard resonant circuit. Activating the resonant circuit causes current to flow through the shape memory actuation element, thereby resistively heating the shape memory actuation element.
The present technology is directed to implantable medical devices comprising an electrical circuit for powering one or more active components of the device, such as an actuation element, an engine, or a sensor. The electrical circuit can include one or more inductors having a plurality of receiving coils that generate a current in response to being exposed to an electromagnetic field. The current generated by the receiving coils can be used to directly or indirectly power the one or more active components. The inductors can have one or more wires having a non-concentric configuration such that, in addition to generating the current for powering the device, the receiving coils also anchor a portion of the device when it is implanted. For example, the receiving coils can be at least partially composed of a superelastic material such that they exhibit superelastic properties at body temperature.
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
A61B 17/00 - Surgical instruments, devices or methods
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid, including a particularized media, to at least partially fragment the thrombus.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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