Abstract

This CASK disorder treating agent contains, as an active ingredient, at least one kinase inhibitor selected from the group consisting of JNK inhibitors and p38 MAPK inhibitors.

IPC Classes  ?

• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61K 31/52 - Purines, e.g. adenine
• A61K 31/416 - 1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
• A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

Problem: To provide a cell culture substrate, a cell culture container, a kit, a method for detaching adherent cells, a method for culturing adherent cells, a cell recovery device, and a cell culture system, with each of which adherent cells can be detached more easily compared with the cases where trypsin is used and the adherent cells can be cultured more efficiently. Solution: A substrate for coating a cell culture container to be used for culturing adherent cells, the substrate comprising a first scaffold component being one or more proteins and a second scaffold component having a composition different from that of the first scaffold component, the second scaffold component being one or more proteins contained in an extracellular matrix.

IPC Classes  ?

• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
• C12N 1/02 - Separating microorganisms from their culture media

Abstract

A white material in which binding between mycelium cells is relaxed while leaving a structure peculiar to a subject mushroom without defibration, and a white material in which the fiber form of the mycelium is maintained while an original solid form is decomposed by defibration and a molded body thereof are obtained. Further addressed is the problem of obtaining a white material in which mycelia fibers are further refined by further defibrating the white material in which the fiber form of mycelia is maintained, and a molded body thereof.　As the solution, a process for producing a white mycelium block comprises repeating once or a plurality of times a series of bleaching/relaxation treatments comprising bringing a fruit body of a mushroom into contact with an alkaline aqueous solution (S101), bringing the fruit body into contact with hydrogen peroxide water (S103), and then irradiating the fruit body with light including ultraviolet rays having a wavelength of at least 380 nm or less (S104), to thereby relax the binding between mycelium cells constituting the fruit body and bleach the fruit body. The process for producing a white mycelium pulp comprises further physically defibrating the white mycelium block (S206). A process for producing a micronized white mycelium pulp comprises further physically defibrating the white mycelium pulp (S207).

IPC Classes  ?

• D21B 1/02 - Pretreatment of the raw materials by physical or chemical means
• A23L 19/00 - Products from fruits or vegetablesPreparation or treatment thereof
• D06M 10/00 - Physical treatment of fibres, threads, yarns, fabrics or fibrous goods made from such materials, e.g. ultrasonic, corona discharge, irradiation, electric currents or magnetic fieldsPhysical treatment combined with treatment with chemical compounds or elements
• D06M 11/00 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising
• D21C 1/06 - Pretreatment of the finely-divided materials before digesting with alkaline reacting compounds

Abstract

The purpose of the present invention is to provide a useful yarn raw material that can be produced even from fibers or the like that are usually difficult to recycle, such as cut pile fibers. The present invention provides a yarn raw material comprising: a fiber having a plurality of hydroxyl groups on the surface thereof; and a polymer that is disposed on the surface of the fiber and has a plurality of carboxy groups and/or phosphate groups, wherein at least a portion of the plurality of hydroxyl groups and a portion of the carboxy groups and/or the phosphate groups form an ester bond and/or a phosphate ester bond.

IPC Classes  ?

• D06M 15/263 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds of unsaturated carboxylic acidsSalts or esters thereof
• D06M 15/03 - Polysaccharides or derivatives thereof
• D06M 15/09 - Cellulose ethers

Abstract

By subjecting a two-layer structure containing a substrate and a thin film formed on the substrate to irradiation with a short pulse laser using interference machining, the method for manufacturing a processed product forms a relief structure having a prescribed period on the surface of the substrate and forms particles that are scattered on the relief structure.

IPC Classes  ?

• B23K 26/354 - Working by laser beam, e.g. welding, cutting or boring for surface treatment by melting
• B23K 26/402 - Removing material taking account of the properties of the material involved involving non-metallic material, e.g. isolators
• B29C 59/16 - Surface shaping, e.g. embossingApparatus therefor by wave energy or particle radiation

Abstract

Provided is an image processing device, an image processing method, or a program that can obtain an image for lens opacity determination that facilitates opacity determination for a lens. An image processing device acquires a transillumination image of a lens captured by a capturing device, and performs a flat correction process to reduce illumination unevenness in the transillumination image. In the flat correction process, an average filter is generated on the basis of an original image of the transillumination image, the original image is divided by the average filter, and values after division are multiplied by an average luminance of the original image. The transillumination image after the flat correction process is converted to a binarized image composed of white and black. Determination for lens opacity is performed on the basis of the binarized image.

IPC Classes  ?

• G06T 7/00 - Image analysis
• G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction

Abstract

A system includes: one or more memories; and one or more processors configured to, acquire three-dimensional data of an environment at a first timing; extract a plurality of pieces of motion data from the one or more memories, the motion data including the target end-effector position and attitude and a swept volume that does not contact the environment; start the task based on first motion data, the first motion data being one of the extracted pieces of motion data; when determination is made that the mobile manipulator comes into contact with the environment, extract, as second motion data, motion data including a swept volume that does not contact the environment based on the three-dimensional data acquired in real time; and generate a transition trajectory for transitioning from a trajectory of the first motion data to a trajectory of the second motion data.

IPC Classes  ?

• G05B 19/4155 - Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by programme execution, i.e. part programme or machine function execution, e.g. selection of a programme
• B25J 9/16 - Programme controls

Abstract

This composition for attracting terrestrial mollusks contains at least one selected from the group consisting of fatty acids having 14-30 carbons in the fatty acid portion, fatty acid esters having 14-30 carbons in the fatty acid portion, and fatty acid amides having 14-30 carbons in the fatty acid portion.

IPC Classes  ?

• A01N 37/02 - Saturated carboxylic acids or thio-analogues thereofDerivatives thereof
• A01M 1/02 - Stationary means for catching or killing insects with devices attracting the insects
• A01M 1/10 - Traps
• A01M 1/20 - Poisoning, narcotising, or burning insects
• A01N 37/06 - Unsaturated carboxylic acids or thio-analogues thereofDerivatives thereof
• A01P 19/00 - Pest attractants

Abstract

An electrode material 1 for secondary batteries that suppresses reductions in electrode capacity and has excellent cycle characteristics includes an electrode active material 10. All or a portion of the surface of the electrode active material 10 is coated with a non-aqueous binder 20 in a shell-like manner.

IPC Classes  ?

• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/139 - Processes of manufacture
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers

Abstract

Provided is a photocatalyst with significantly enhanced water splitting performance in YTOS or in a composition in which the yttrium element of YTOS has been replaced with another element. Also provided is a method for producing a photocatalyst that has a composition represented by the following general formula (I), the method including mixing, with a raw material of the photocatalyst, a flux component at a mass ratio of 0.01 times to 50 times, the flux component being composed of one or more chlorides and/or iodides of at least one selected from Li, Na, K, Rb, Mg, Ca, Sr, and Ba, and calcining a resultant product at 450° C. to 1050° C.: Provided is a photocatalyst with significantly enhanced water splitting performance in YTOS or in a composition in which the yttrium element of YTOS has been replaced with another element. Also provided is a method for producing a photocatalyst that has a composition represented by the following general formula (I), the method including mixing, with a raw material of the photocatalyst, a flux component at a mass ratio of 0.01 times to 50 times, the flux component being composed of one or more chlorides and/or iodides of at least one selected from Li, Na, K, Rb, Mg, Ca, Sr, and Ba, and calcining a resultant product at 450° C. to 1050° C.: MaTibOcSd  (I) Provided is a photocatalyst with significantly enhanced water splitting performance in YTOS or in a composition in which the yttrium element of YTOS has been replaced with another element. Also provided is a method for producing a photocatalyst that has a composition represented by the following general formula (I), the method including mixing, with a raw material of the photocatalyst, a flux component at a mass ratio of 0.01 times to 50 times, the flux component being composed of one or more chlorides and/or iodides of at least one selected from Li, Na, K, Rb, Mg, Ca, Sr, and Ba, and calcining a resultant product at 450° C. to 1050° C.: MaTibOcSd  (I) (where M is a combination of one or more selected from Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, and Y, a is a number of 1.7 to 2.3, b is a number of 2, c is a number of 4.7 to 5.3, and d is a number of 1.7 to 2.3).

IPC Classes  ?

• C25B 11/087 - Photocatalytic compound
• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 1/55 - Photoelectrolysis
• C25B 9/50 - Cells or assemblies of cells comprising photoelectrodesAssemblies of constructional parts thereof

Abstract

Disclosed is a pharmaceutical composition for treating facioscapulohumeral dystrophy, the pharmaceutical composition containing a compound represented by formula (1) or a salt thereof as an active ingredient. (In formula (1), X represents H, a C1-C6 alkyl group, a C2-C6 alkenyl group, or a C2-C6 alkynyl group; and R1, R2, R3and R4 each independently represent H, a C1-C6 alkyl group, a C2-C6 alkenyl group, or a C2-C6 alkynyl group.)

IPC Classes  ?

• A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• C07D 277/46 - Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Abstract

An insulating resin comprising (A) a thermoplastic resin which is at least one resin selected from among polycarbonate resins, polyester resins, and polyarylate resins and (B) a metal diketone complex crosslinked by an ether bond and containing at least one β-diketone as a ligand.

IPC Classes  ?

• C08L 101/12 - Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
• C08K 5/04 - Oxygen-containing compounds
• C08L 67/00 - Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chainCompositions of derivatives of such polymers
• C08L 69/00 - Compositions of polycarbonatesCompositions of derivatives of polycarbonates
• H01B 3/42 - Insulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances plasticsInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances resinsInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances waxes polyestersInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances plasticsInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances resinsInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances waxes polyethersInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances plasticsInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances resinsInsulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances waxes polyacetals

Abstract

A positive electrode material for secondary batteries that has exceptional high rate characteristics and cycle characteristics, the positive electrode material containing a positive electrode active material 10 and a crystalline metal oxide 20 that is attached to part of the surface of the positive electrode active material 10.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates

Abstract

The present invention provides a method for producing a chimeric antigen receptor T (CAR-T) cell, including a step of bead separating with a specific factor a T cell from a T cell source, wherein the specific factor is CD45RA+ or the like. The method enables production of CAR-T cells high antitumor property, and can produce highly functional CAR-T cells conveniently in a short time at a low cost.

IPC Classes  ?

• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells

Abstract

This hydrazine-containing waste water treatment method includes a photocatalyst treatment step for performing oxidative decomposition of hydrazine in hydrazine-containing waste water with a photocatalyst. The hydrazine-containing waste water treatment facility 1 is provided with: a reaction tank 20 in which hydrazine-containing waste water 10 is stored; and a photocatalyst 30 which is provided in the reaction tank 20.

IPC Classes  ?

• C02F 1/72 - Treatment of water, waste water, or sewage by oxidation
• B01J 23/02 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the alkali- or alkaline earth metals or beryllium
• B01J 35/39 - Photocatalytic properties

Abstract

A determination device 1 includes: an acquisition unit 21 that acquires digital color image data 11 of a region of interest in melanonychia of a subject; a calculation unit 23 that calculates an indicator value 12 from variation in RGB values of each pixel of the digital color image data 11; and an output unit 24 that outputs a result of determining that the melanonychia is malignant if the indicator value 12 is higher than a threshold value and determining that the melanonychia is benign if the indicator value 12 is lower than the threshold value.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/103 - Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
• G06T 5/00 - Image enhancement or restoration
• G06T 7/00 - Image analysis
• G06T 7/90 - Determination of colour characteristics

Abstract

In a carbon molecular sieve of the present invention, the half-value width of a main peak of an oxygen adsorption rate constant distribution is less than or equal to 0.35 s-122 at 25℃ according to the BET method is 300 m2/g to 600 m2/g, inclusive.

IPC Classes  ?

• C01B 32/05 - Preparation or purification of carbon not covered by groups , , ,
• B01D 53/047 - Pressure swing adsorption
• B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C01B 37/00 - Compounds having molecular sieve properties but not having base-exchange properties

Abstract

[Problem] To make it possible to provide food information optimal for an individual user. [Solution] The present invention is characterized by comprising: a prediction model storage unit that stores a prediction model which predicts, for each user, body data relating to the body of the user on the basis of intake amounts of a plurality of food components taken by the user and which includes, for each of the food components, the degree by which the food component improves or deteriorates the body data; a food database that stores the amounts of food components contained in food; and an influence amount calculation unit that calculates an influence amount which is the amount by which the food improves or deteriorates the body data of the user on the basis of the amounts of the food components contained in the food and the degree relating to the food components.

IPC Classes  ?

• G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets

Abstract

A rubber composition comprising a nanocellulose and a rubber component, wherein the nanocellulose contains a cellulose raw material oxide derived from hypochlorous acid or a salt thereof and does not substantially contain an N-oxyl compound. The ratio of the value of elongation at break of a rubber formed from said rubber composition to the value of elongation at break of a rubber formed from a control rubber composition in which the nanocellulose has been removed from said rubber composition is at least 0.90 and less than 1.15.

IPC Classes  ?

• C08L 21/00 - Compositions of unspecified rubbers
• C08J 3/22 - Compounding polymers with additives, e.g. colouring using masterbatch techniques
• C08J 5/04 - Reinforcing macromolecular compounds with loose or coherent fibrous material
• C08L 1/02 - CelluloseModified cellulose

Abstract

Single crystalline nanoparticles that are tantalum nitride doped with at least one metal are described. The single crystalline nanoparticles can be doped with two metals such as Zr and Mg. The single crystalline nanoparticles can be Ta3N5:Mg+Zr, or Ta3N5:Mg, or Ta3N5:Zr or any combination thereof. Catalyst containing the single crystalline nanoparticles alone or with one or more co-catalyst are further described along with methods of making the nanoparticles and catalyst. Methods to split water utilizing the catalyst are further described.

IPC Classes  ?

• C30B 29/38 - Nitrides
• B01J 27/24 - Nitrogen compounds
• B01J 35/23 - Catalysts, in general, characterised by their form or physical properties characterised by their non-solid state in a colloidal state
• B01J 35/39 - Photocatalytic properties
• B01J 35/45 - Nanoparticles
• B01J 35/55 - Cylinders or rings
• B01J 37/02 - Impregnation, coating or precipitation
• B01J 37/16 - Reducing

Abstract

The carbon nanotube structure in which a plurality of carbon nanotubes are assembled includes a joining portion of end portions of carbon nanotubes and a joining portion of an end portion and a side wall portion of the carbon nanotubes.

IPC Classes  ?

• C01B 32/174 - DerivatisationSolubilisationDispersion in solvents
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

This diagnosis method comprises: a marker complex concentration measurement step for disposing, on a substrate, a photoacid and an anti-marker antibody that specifically binds with a marker and providing a test sample thereon to measure the concentration of a marker complex in which the anti-marker antibody and a marker in the test sample are bound; and a marker dissociation step for irradiating the photoacid with light to dissociate the marker from the marker complex.

IPC Classes  ?

• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 29/02 - Analysing fluids
• G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

Abstract

Disclosed is a magnetic sensor head which comprises an optical fiber, a GI fiber having one end that is optically connected to the optical fiber, a magnetic film that is bonded to the other end of the GI fiber, and a reflective film that is bonded to a surface of the magnetic film, the surface being on the reverse side of the surface that is bonded to the GI fiber. The magnetic film is formed of a rare earth iron garnet thin film; and the slope of the sum of squared differences of the rare earth iron garnet thin film with respect to the applied magnetic field is 100 or more.

IPC Classes  ?

• G01R 33/032 - Measuring direction or magnitude of magnetic fields or magnetic flux using magneto-optic devices, e.g. Faraday

Abstract

The invention provides a semipermeable composite membrane that reduces an environmental load, and a method of producing the semipermeable composite membrane. A semipermeable composite membrane 100 includes, on a porous support 102, a semipermeable membrane 104 containing a crosslinked polyamide 120 and a cellulose nanofiber 110. A method of producing the semipermeable composite membrane includes obtaining a mixed solution containing the cellulose nanofiber 110, water, and an amine component, and obtaining the semipermeable composite membrane 100 by making the mixed solution be in contact with the porous support 102, thereafter, causing a cross-linking reaction of the amine component in the mixed solution, with the amine component adhering to the porous support 102.

IPC Classes  ?

• B01D 69/12 - Composite membranesUltra-thin membranes
• B01D 61/02 - Reverse osmosisHyperfiltration
• B01D 63/10 - Spiral-wound membrane modules
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranesMembrane supports
• B01D 71/10 - CelluloseModified cellulose
• B01D 71/56 - Polyamides, e.g. polyester-amides
• B32B 27/06 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance
• B32B 27/28 - Layered products essentially comprising synthetic resin comprising copolymers of synthetic resins not wholly covered by any one of the following subgroups
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 103/08 - Seawater, e.g. for desalination

Abstract

A method for producing a tantalum nitride material that includes a nitriding step that heats a precursor containing a lithium tantalum composite oxide in the presence of a nitrogen compound.

IPC Classes  ?

• C01B 21/06 - Binary compounds of nitrogen with metals, with silicon, or with boron
• B01J 27/24 - Nitrogen compounds
• B01J 35/02 - Solids
• B01J 37/04 - Mixing
• B01J 37/08 - Heat treatment

Abstract

Provided is a peptide which comprises no more than 25 amino acids and has an amino acid sequence of (i) or (ii). An amino acid sequence comprises the same citrulline as three or more citrullines in a partial sequence of SEQ ID NO: 1., with respect to (i) a partial sequence of a SEQ ID NO: 1 amino acid sequence, which is an amino acid sequence having eight or more continuous amino acids comprising one or more citrullines, and (ii) a partial sequence of SEQ ID NO: 1, which is an amino acid sequence having 13 or more continuous amino acids comprising one or more citrullines. Further, an amino acid sequence of ten or more remaining amino acids other than the one or more citrullines has at least 90% identity with an amino acid sequence of ten or more remaining amino acids other than the one or more citrullines among the partial sequence of SEQ ID NO: 1.

IPC Classes  ?

• C07K 14/75 - Fibrinogen
• A61K 38/10 - Peptides having 12 to 20 amino acids
• A61P 35/00 - Antineoplastic agents
• A61P 35/04 - Antineoplastic agents specific for metastasis
• C12N 15/12 - Genes encoding animal proteins

Abstract

Provided is a drug for preventing or treating heart failure, that is effective and that does not have a blood pressure lowering effect.　The present invention pertains to: a pharmaceutical composition for preventing or treating heart failure or skeletal muscle failure, the pharmaceutical composition containing a TRPC3/6/7 channel activator; and a related screening method.

IPC Classes  ?

• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61K 31/05 - Phenols
• A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
• C07D 401/00 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
• G01N 33/15 - Medicinal preparations
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

Provided is a reagent for measuring fluorine ion concentration, which makes it possible to measure fluorine ion concentration by using visible light.　The present invention provides a reagent for measuring fluorine ion concentration, including a metal organic framework and pigment molecules that can absorb visible light, wherein the pigment molecules are coordinate-bonded to the metal organic framework, and the reagent is composed such that when the reagent is mixed with an aqueous sample that may contain fluorine ions, the fluorine ions become coordinated with the metal in the metal organic framework, and the pigment molecules become released from the metal organic framework.

IPC Classes  ?

• G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods
• G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
• G01N 21/59 - Transmissivity
• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour

Abstract

Provided are a cell culture member having excellent cell culture performance and its long-term stability, and a method for modifying the surface thereof. The cell culture member according to the present invention is a cell culture member having at least a holding region that holds an adherent cell and contains a polymer compound, wherein at least a part of the holding region is a surface-modified region in which a functional group containing a nitrogen atom is directly chemically bonded to a part of carbon atoms and/or silicon atoms constituting the polymer compound, and the present invention can provide a cell culture member that improves adhesiveness of the adherent cell to the surface-modified region, suppresses deterioration over time of adhesiveness, and is excellent in cell culture performance and its long-term stability.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• C08J 7/12 - Chemical modification

Abstract

Provided are a cell culture member having excellent cell culture performance and its long-term stability, and a method for modifying the surface thereof. The cell culture member according to the present invention is a cell culture member having at least a holding region that holds an adherent cell and contains a polymer compound, wherein at least a part of the holding region is a surface-modified region in which a fluorine atom is directly chemically bonded to a part of carbon atoms and/or silicon atoms constituting the polymer compound, and the present invention can provide a cell culture member that improves adhesiveness of the adherent cell to the surface-modified region, suppresses deterioration over time of adhesiveness, and is excellent in cell culture performance and its long-term stability.

IPC Classes  ?

• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
• C08J 7/12 - Chemical modification

Abstract

Provided is a method for operating a reverse osmosis membrane device which has a reverse osmosis membrane element and in which treated water is obtained by passing water to be treated that contains a scale component through the reverse osmosis membrane device, said method being characterized in that: the reverse membrane element includes a reverse osmosis membrane and a flow path member; a dense layer of the reverse osmosis membrane contains carbon nanotubes and cellulose nanofibers; the flow path member contains carbon nanotubes; and a scale dispersant is added to the water to be treated.

IPC Classes  ?

• B01D 61/10 - AccessoriesAuxiliary operations
• B01D 63/00 - Apparatus in general for separation processes using semi-permeable membranes
• B01D 65/02 - Membrane cleaning or sterilisation
• B01D 71/02 - Inorganic material
• B01D 71/10 - CelluloseModified cellulose
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 5/00 - Softening waterPreventing scaleAdding scale preventatives or scale removers to water, e.g. adding sequestering agents
• C02F 5/08 - Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents
• C02F 5/10 - Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents using organic substances
• C02F 5/14 - Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents using organic substances containing phosphorus

Abstract

The present invention improves input/output characteristics of a lithium ion battery.　Coated lithium-transition metal oxide particles according to the present invention are obtained by at least partially coating the surfaces of lithium-transition metal oxide particles with a copolymer which is represented by formula (1) and which has a weight-average molecular weight of 200,000-600,000. The copolymer is cross-linked by ring opening of an oxetane ring. In formula (1), m and n each represent a number of 1 or greater. R1and R2each represent a hydrogen atom or a methyl group. R3represents an alkyl group having 1-5 carbon atoms. R4represents an alkanediyl group having 1-5 carbon atoms. R5 represents a hydrogen atom or an alkyl group having 1-5 carbon atoms.

IPC Classes  ?

• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy

Abstract

Destabilize a protein at least partially, provide the destabilized protein in a presence of a candidate functional substance, induce its restabilization, and determine the effect of a presence of the candidate functional substance in influencing a function of the protein, in order to search for functional substances that selectively bind to a non-native state of the protein and influence the function of the protein.

IPC Classes  ?

• G16B 15/30 - Drug targeting using structural dataDocking or binding prediction

Abstract

Provided are a particle two-dimensional acoustic focusing device that can efficiently focus and concentrate particles present in liquid flowing in a channel by using the acoustic effect of ultrasonic waves while having a simple configuration, and an acoustic concentration device using the particle two-dimensional acoustic focusing device. This particle two-dimensional acoustic focusing device is configured so as to focus particles contained in liquid flowing in a channel to the center of the cross-section of the channel by using ultrasonic waves and comprises: a rectangular channel 10 having a substantially rectangular cross-sectional shape when broken orthogonally to the extension direction of the channel; and a single ultrasonic wave generator 20 that simultaneously irradiates the interior of the rectangular channel 10 with a first ultrasonic wave and a second ultrasonic wave in a composite state, the first ultrasonic wave being generated so that the length of a long side a of the rectangle of the rectangular channel 10 is substantially equivalent to the length of a half wavelength, the second ultrasonic wave being generated so that the length of a short side b of the rectangle of the rectangular channel 10 is substantially equivalent to the length of the half wavelength.

IPC Classes  ?

• B01D 43/00 - Separating particles from liquids, or liquids from solids, otherwise than by sedimentation or filtration
• B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations
• G01N 37/00 - Details not covered by any other group of this subclass

Abstract

The present invention addresses the problem of providing an EGFR CAR-T cell which is expected to be effective against a tumor in which an EGFR is expressed. The present invention provides: a polynucleotide encoding a chimeric antigen receptor (chimeric antigen receptor: CAR) protein comprising a target binding domain capable of binding to an epidermal growth factor receptor (EGFR), a transmembrane domain and an intracellular signaling domain, in which the target binding domain is a ligand of an EGFR; a vector carrying the polynucleotide; and a genetically modified cell into which the polypeptide or the vector has been introduced.

IPC Classes  ?

• C12N 15/62 - DNA sequences coding for fusion proteins
• A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A61P 1/18 - Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
• A61P 11/00 - Drugs for disorders of the respiratory system
• A61P 15/00 - Drugs for genital or sexual disordersContraceptives
• A61P 17/00 - Drugs for dermatological disorders
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 35/00 - Antineoplastic agents
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
• C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
• C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Abstract

Provided is a curved surface robot (1) comprising an actuator connecting body (5) configured by connecting a plurality of sheet-like actuators (2). Each of the sheet-like actuators (2) is deformed into a curved surface shape along a designated constant mean curvature curved surface, and thereby the actuator connecting body (5) is deformed into various curved surface shapes. Since a constant mean curvature curved surface can take an isothermal coordinate system, a base coordinate system set on the curved surface of the actuator connecting body (5) and a homogeneous transformation matrix orthogonal to each point on the curved surface can be considered, and conventional coordinate transformation of robotics can be applied as is. It is possible to realize a multi-degree-of-freedom curved surface robot (combination of robot and kinematics) that can express a complicated curved surface with a small number of parameters and can acquire a homogeneous transformation matrix on the robot more easily.

IPC Classes  ?

• B25J 9/08 - Programme-controlled manipulators characterised by modular constructions

Abstract

[Problem] To provide: a textile product which has an excellent ability to adsorb fouling substances and which can easily release the fouling substances that have been adsorbed; a method for producing a textile product; a method for regenerating a textile product; and a regenerant for a textile product. [Solution] This textile product comprises a fibrous base, a polymer layer fixed, by covalent bonding, to at least a part of the surface of the fibrous base, and a clay layer fixed to the surface of the polymer layer, wherein the polymer layer includes a polymer having a plurality of groups which can electrostatically fix the clay layer.

IPC Classes  ?

• D06M 11/36 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with oxygen, ozone, ozonides, oxides, hydroxides or percompoundsSalts derived from anions with an amphoteric element-oxygen bond with oxides, hydroxides or mixed oxidesTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with oxygen, ozone, ozonides, oxides, hydroxides or percompoundsSalts derived from anions with an amphoteric element-oxygen bond with salts derived from anions with an amphoteric element-oxygen bond
• B32B 5/24 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by the presence of two or more layers which comprise fibres, filaments, granules, or powder, or are foamed or specifically porous one layer being a fibrous or filamentary layer
• B32B 9/04 - Layered products essentially comprising a particular substance not covered by groups comprising such substance as the main or only constituent of a layer, next to another layer of a specific substance
• D06M 13/513 - Compounds with at least one carbon-metal or carbon-boron, carbon-silicon, carbon-selenium, or carbon-tellurium bond with at least one carbon-silicon bond
• D06M 15/61 - Polyamines

Abstract

This antitumor agent comprises, as an active ingredient, an RNA which has a base sequence selected from the group consisting of the following (1) and (2) and has at least one nucleotide unit represented by formula (1) in a 3'-terminal region within 20 bases from the 3'-terminal thereof and/or in a 5'-terminal region within 25 bases from the 5'-terminal thereof. (1) A base sequence represented by SEQ ID NO: 2 or a base sequence having at least 90% identity with the sequence, and (2) a base sequence having 20 to 200 consecutive bases among the base sequences of (1) above (in formula (1), R1represents a hydroxyl group, a hydroxyl group in which a hydrogen atom is substituted with an alkyl group or an alkenyl group, or a halogen atom; R2represents NHR3having a linking group, and the linking group is a divalent hydrocarbon group having at least one carbon atom; R3represents a hydrogen atom, an alkyl group, or an alkenyl group; n represents 0 or 1; X1represents an oxygen atom or a sulfur atom; X2represents OH (or O-) or SH (or S-); and B represents a purine base or a pyrimidine base.)

IPC Classes  ?

• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 35/00 - Antineoplastic agents
• A61P 35/04 - Antineoplastic agents specific for metastasis
• A61P 37/04 - Immunostimulants
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
• A61K 31/712 - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose

Abstract

An intermediate comprising a first rubber component, a nanocellulose, and a cation having a valence of three or more, wherein the nanocellulose is derived from an oxide of a cellulose-based material obtained by means of hypochlorite or a salt thereof, and is not derived from an oxide of a cellulose-based material obtained by means of an N-oxyl compound. An intermediate comprising a first rubber component, a nanocellulose, and a polymer having a repeating unit derived from an unsaturated carboxylate including a monovalent metal ion and/or an unsaturated carboxylate including a monovalent metal ion, wherein the nanocellulose is derived from an oxide of a cellulose-based material obtained by means of hypochlorite or a salt thereof, and is not derived from an oxide of a cellulose-based material obtained by means of an N-oxyl compound.

IPC Classes  ?

• C08L 21/00 - Compositions of unspecified rubbers
• C08J 3/20 - Compounding polymers with additives, e.g. colouring
• C08L 1/00 - Compositions of cellulose, modified cellulose, or cellulose derivatives
• C08L 101/08 - Carboxyl groups

Abstract

An intermediate according to one embodiment of the present invention contains a rubber component, carboxyl group-containing cellulose nanofibers, and a trivalent or higher cation. The cellulose nanofibers include nanofibers derived from oxidized cellulose that has been oxidized using an N-oxyl compound. In addition, an intermediate according to one embodiment of the present invention contains a rubber component, carboxyl group-containing cellulose nanofibers, and an unsaturated carboxylic acid salt containing a monovalent metal ion and/or a polymer having a repeating unit derived from an unsaturated carboxylic acid salt containing a monovalent metal ion. The cellulose nanofibers include nanofibers derived from oxidized cellulose that has been oxidized using an N-oxyl compound.

IPC Classes  ?

• C08L 21/00 - Compositions of unspecified rubbers
• C08J 3/20 - Compounding polymers with additives, e.g. colouring
• C08J 3/22 - Compounding polymers with additives, e.g. colouring using masterbatch techniques
• C08K 3/10 - Metal compounds
• C08K 5/098 - Metal salts of carboxylic acids
• C08L 1/04 - OxycelluloseHydrocellulose
• C08L 21/02 - Latex
• C08L 33/02 - Homopolymers or copolymers of acidsMetal or ammonium salts thereof

Abstract

To set a scale for three dimensional data composed from point cloud data: a plurality of reference objects (22) of sizes and shapes known in advance are disposed around an object (20) under measurement; image data or position data obtained by imaging the object (20) under measurement together with the plurality of reference objects (22) from various angles is input to a computer (30); the known sizes and shapes of the reference objects (22) are input to the computer (30); and the computer (30) acquires point cloud data for the object (20) under measurement and each reference object (22) from a plurality of pieces of the image data or a plurality of pieces of the position data, determines, as reference objects, objects in the point cloud data having sizes and shapes within prescribed error ranges with respect to the sizes and shapes input for the reference objects (22), and sets the overall scale of the point cloud data by extending/contracting and/or twisting the point cloud data such that each of the determined reference objects has the input size and shape.

IPC Classes  ?

• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• G06T 7/50 - Depth or shape recovery
• G01S 17/06 - Systems determining position data of a target

Abstract

Provided is a chain transfer agent that is a chain transfer agent other than a mercaptan compound and can sufficiently control molecular weight.　The present invention provides a chain transfer agent represented by formula (1). [In formula (1): X is a group selected from among a cyano group, an optionally substituted aryl group, an acyl group, a carboxy group, COOR122, C(O)NHR1, C(O)NR122, SOR122R133R1and OR1; Y and Z are each a group selected from among a cyano group, an optionally substituted aryl group, an acyl group a carboxy group, COOR122, C(O)NHR1, C(O)NR122, SOR122R133R1, OR1, OC(O)R1, N(H)C(O)R1and a halogen, or Y and Z are bonded together to form an optionally substituted carbocyclic structure or an optionally substituted heterocyclic structure; X, Y and Z may be either the same or different; R1is an optionally substituted alkyl group having 1-8 carbon atoms; Q is hydrogen, an optionally substituted alkyl group having 1-6 carbon atoms or a phenyl group; R2and R3are hydrogen or a group selected from among an alkyl group having 2-6 carbon atoms, an optionally substituted aryl group and an optionally substituted heterocyclic structure; and R2and R3may be either the same or different (except when R2and R3 are both hydrogen).]

IPC Classes  ?

• C08F 2/38 - Polymerisation using regulators, e.g. chain terminating agents
• C08F 20/18 - Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids

Abstract

Provided is a detection device with which it is possible to detect oral microbes in a highly accurate manner. This detection device has: a container for accommodating a sample containing contaminants in the oral cavity and composite particles in which a fluorescent labelling substance is bound to oral microbes; a radiation unit for radiating, into the container, excitation light for exciting the fluorescent labelling substance of the composite particles; a light detection unit for detecting light from the container in a state in which the fluorescent labelling substance is excited; and a detection unit for optically detecting the composite particles in the container on the basis of the result of the detection by the light detection unit, the excitation light being light in the wavelength band of 550 nm or above with which excitation of the contaminants is minimized.

IPC Classes  ?

• G01N 21/64 - FluorescencePhosphorescence
• G01N 33/483 - Physical analysis of biological material
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

A connection structural body includes: a first connection terminal including a first opposing surface; a first roughened-surface copper metal film formed on the first opposing surface; a second connection terminal including a second opposing surface facing the first opposing surface; and a second roughened-surface copper metal film formed on the second opposing surface and bonded to the first roughened-surface copper metal film. The first roughened-surface copper metal film includes a structure in which first deposits of copper are piled over one another on the first opposing surface. The second roughened-surface copper metal film includes a structure in which second deposits of copper are piled over one another on the second opposing surface. A bonded portion of the first and second roughened-surface copper metal films includes a structure in which the first deposits and the second deposits are piled such that the bonded portion includes pores.

IPC Classes  ?

• H01L 23/00 - Details of semiconductor or other solid state devices
• H01L 23/498 - Leads on insulating substrates

Abstract

This free-range livestock management server device: acquires information pertaining to individuals or locations; identifies individuals on the basis of the acquired information; identifies locations on the basis of the acquired information; ascertains states of the individuals or locations on the basis of the acquired information; monitors for an abnormal state of the individuals or locations on the basis of the acquired information; organizes, for each individual or location that has been identified, information pertaining to the identified individuals or locations, ascertained states, and monitored abnormal state, and thereby associates such information with each individual or location that has been identified; stores the organized and associated information; determines, out of the stored information, the urgency of information pertaining to the abnormal state of the individuals or locations, such determination being on the basis of a preset criterion; and generates notice information on the basis of information determined to be urgent and transmit same to a predetermined terminal.

IPC Classes  ?

• A01K 29/00 - Other apparatus for animal husbandry

Abstract

An object of the present invention is to provide a therapeutic strategy in the solid tumor area and a means useful therefor to further advance the clinical application of CAR therapy. There is prepared a gene-modified lymphocyte which expresses a chimeric antigen receptor having an EphrinB2 extracellular domain at the antigen recognition site.

IPC Classes  ?

• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C07K 14/725 - T-cell receptors
• A61P 35/00 - Antineoplastic agents
• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants

Abstract

A negative electrode active material (102) for a secondary battery according to the present invention comprises: active material particles (106) which contain a self-assembled monolayer film 104 having a silicon composite body (103) and an amino group that covers the surface of the silicon composite body (103); and a binder (105) which is bonded to the self-assembled monolayer film 104 via the amino group. The binder (105) comprises first carbon nanotubes having a length of not more than 1000 nm, and second carbon nanotubes having a length of not less than 2 μm.

IPC Classes  ?

• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides
• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/052 - Li-accumulators
• H01M 10/0567 - Liquid materials characterised by the additives

Abstract

[Problem] To provide a cell culture substrate, a cell culture container and an adherent cell detachment method, whereby adherent cells can be more simply detached compared with the case of using trypsin. [Solution] A cell culture substrate to be used for coating a cell culture container, said cell culture substrate containing, as an active ingredient, at least one protein selected from among silk protein, a hydrolysate of silk protein, fibroin and a hydrolysate of fibroin.

IPC Classes  ?

• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

Abstract

[Problem] To enable management of health in consideration of individual differences. [Solution] An information processing system according to the present invention comprises a measurement storage unit that stores a measurement linked to the achievement goals of a user, an intake storage unit that stores the intake of a plurality of nutrients taken by the user, an analysis unit that analyzes a relationship between the intake of nutrients and the measurement to specify an improvement factor that is a nutrient contributing to improvement of the measurement and a deterioration factor that is a nutrient contributing to deterioration of the measurement, a meal menu storage unit that stores information specifying content of nutrients contained in the meal menu, and a meal menu proposition unit that modifies the meal menu by increasing the content of the improvement factor and/or decreasing the content of the deterioration factor, and proposes the modified meal menu.

IPC Classes  ?

• G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets

Abstract

353535x22, is disclosed. The nanoparticles can further be modified to include a water reducing catalyst. A water splitting catalyst is further disclosed. Methods of making the nanoparticles and catalyst are also disclosed. Methods to split water utilizing the catalyst are further described.

IPC Classes  ?

• B01J 23/20 - Vanadium, niobium or tantalum
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 37/02 - Impregnation, coating or precipitation

Abstract

The present invention addresses the problem of providing an aerosol composition that does not substantially contain a surfactant and has good dispersion stability even when an oily component is contained in a large amount.　This problem is solved by an aerosol composition containing water, an oily component, and a water-soluble polymer, wherein the water-soluble polymer contains at least one selected from the group consisting of polyvinyl alcohol and polyvinyl pyrrolidone, the content of the water-soluble polymer in the aerosol composition is 0.01-2.5 mass%, the aerosol composition forms an emulsion, the average particle size of the droplets of the emulsion is 0.5-7.0 μm, and the aerosol composition does not substantially contain a surfactant.

IPC Classes  ?

• A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
• A61Q 19/00 - Preparations for care of the skin
• C09K 3/30 - Materials not provided for elsewhere for aerosols
• A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
• A61K 8/06 - Emulsions
• A61K 8/31 - Hydrocarbons
• A61K 8/34 - Alcohols
• A61K 8/36 - Carboxylic acidsSalts or anhydrides thereof
• A61K 8/37 - Esters of carboxylic acids
• A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
• A61K 8/891 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
• A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
• B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided forMaking microcapsules or microballoons

Abstract

This invention provides a fiber melt spinning method that uses a 3D printer.　The objective of this invention is to provide a spinning method that is very useful for the production of fibers endowed with shape memory and other desired functionalities.

IPC Classes  ?

• D01D 5/08 - Melt-spinning methods
• B29C 64/209 - HeadsNozzles
• D01F 6/70 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolycondensation products from polyurethanes

Abstract

Provided is an IGF1R CAR-T cell that is expected to be effective against tumors that express IGF1R. Provided is a polynucleotide that encodes a chimeric antigen receptor (CAR) protein having a target-binding domain that binds to the insulin-like growth factor-1 receptor (IGF1R), a transmembrane domain, and an intracellular signaling domain, wherein the target-binding domain is the pre-pro-precursor for insulin-like growth factor (IGF) or its E-domain-deleted fragment. Also provided are a vector containing this polynucleotide and genetically modified cells into which this polypeptide or vector has been introduced.

IPC Classes  ?

• C12N 15/62 - DNA sequences coding for fusion proteins
• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61P 35/00 - Antineoplastic agents
• A61P 35/02 - Antineoplastic agents specific for leukemia
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C07K 14/65 - Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
• C07K 14/725 - T-cell receptors
• C07K 19/00 - Hybrid peptides

Abstract

Provided are a textile product capable of firmly fixing a functional material onto the surface thereof and having excellent washing durability, and a method for producing the textile product, being capable of efficiently producing the textile product. Provided is a textile product including: a textile base material; a surface treatment layer formed of a silane coupling agent on at least a part of the surface of the textile base material; and a zirconium phosphate layer fixed on the surface treatment layer, wherein the silane coupling agent includes a silane compound having an amino group.

IPC Classes  ?

• D06M 13/513 - Compounds with at least one carbon-metal or carbon-boron, carbon-silicon, carbon-selenium, or carbon-tellurium bond with at least one carbon-silicon bond
• D06M 11/71 - Salts of phosphoric acids
• D06M 15/15 - Proteins or derivatives thereof
• D06M 15/05 - Cellulose or derivatives thereof
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties

Abstract

A production apparatus for a metal oxide single crystal according to the present invention includes a crucible for housing a crystal raw material and a seed crystal, which has a first end and a second end, and in which the crystal raw material is disposed on a first end side, and the seed crystal is disposed on a second end side, a heater that heats the crucible, and a cooling rod, which has a third end and a fourth end, and in which the third end is provided in contact with or in proximity to the second end of the crucible so as to cool the second end by depriving the second end of heat.

IPC Classes  ?

• C30B 11/00 - Single-crystal-growth by normal freezing or freezing under temperature gradient, e.g. Bridgman- Stockbarger method
• C30B 29/16 - Oxides
• C30B 35/00 - Apparatus not otherwise provided for, specially adapted for the growth, production or after-treatment of single crystals or of a homogeneous polycrystalline material with defined structure

Abstract

A positive electrode according to the present invention is a positive electrode of a lithium ion secondary battery in which a coating film containing a positive electrode active material is pressed against a surface of a positive electrode base material, and the positive electrode active material is a mixture of a first active material containing single particles of lithium composite oxide and a second active material containing secondary particles which are aggregated single particles of lithium composite oxide.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy

Abstract

The present invention addresses the problem of providing a pharmaceutical composition for preventing and/or treating heart failure. The present invention pertains to a pharmaceutical composition or the like that is for preventing and/or treating heart failure and that contains: a compound represented by general formula (1) [in the formula, A represents an optionally substituted benzene ring, B represents an optionally substituted aryl or an optionally substituted heteroaryl, X represents an oxygen atom or a sulfur atom, Y represents a nitrogen atom or a carbon atom, each R1independently represents a lower alkyl, two R1s may be bound to each other to form a spiro ring or a crosslinked structure, or two R1s may be bound to each other to form, together with a nitrogen atom and a carbon atom forming a ring including Y, a saturated fused heterocyclic ring, and p represents 0, 1, or 2, or (R1pp represents oxo]; a salt thereof; or a prodrug thereof.

IPC Classes  ?

• A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
• A61K 31/4418 - Non-condensed pyridinesHydrogenated derivatives thereof having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
• A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
• A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
• A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure

Abstract

xyz2xyz22O overlapping in layers; a platinic acid nanosheet having a thickness of 1 nm or less; and a platinum nanosheet having a thickness of 0.6 nm or less.

IPC Classes  ?

• C01G 55/00 - Compounds of ruthenium, rhodium, palladium, osmium, iridium, or platinum
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

Provided are a ruminant feed composition that can be easily manufactured and is capable of reducing the amount of methane gas produced in the body, a ruminant feed and a method for manufacturing a ruminant feed composition. The method for manufacturing a ruminant feed composition according to the present invention comprises: a step for housing a persimmon material in a sealed space; a step for heating the sealed space; a step for heating and pressurizing the persimmon material by water vapor in the sealed space for 2-5 hours under a temperature of 120-134°C to decompose the material; and a step for cooling the sealed space. In the step for heating the sealed space, the sealed space is heated while allowing the water vapor pressure in the sealed space to follow the saturated water vapor pressure curve. In the step for cooling the sealed space, the sealed space is cooled while allowing the water vapor pressure in the sealed space to follow the saturated water vapor pressure curve.

IPC Classes  ?

• A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
• A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

Abstract

abcdd ... (I) (where M is one element or a combination of two or more elements selected from among Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, and Y, a=1.7-2.3, b=2, c=4.7-5.3, and d=1.7-2.3.)

IPC Classes  ?

• B01J 35/02 - Solids
• B01J 27/045 - Platinum group metals
• B01J 37/06 - Washing
• B01J 37/08 - Heat treatment
• C01B 3/04 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of inorganic compounds, e.g. ammonia
• C01B 13/02 - Preparation of oxygen
• C01G 23/00 - Compounds of titanium
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 1/55 - Photoelectrolysis
• C25B 9/00 - Cells or assemblies of cellsConstructional parts of cellsAssemblies of constructional parts, e.g. electrode-diaphragm assembliesProcess-related cell features
• C25B 9/50 - Cells or assemblies of cells comprising photoelectrodesAssemblies of constructional parts thereof
• C25B 11/049 - Photocatalysts
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/077 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the compound being a non-noble metal oxide
• C25B 11/087 - Photocatalytic compound
• C25B 11/093 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds at least one noble metal or noble metal oxide and at least one non-noble metal oxide

Abstract

221-xx222 by a solid-phase method.

IPC Classes  ?

• C01G 45/00 - Compounds of manganese
• C01G 55/00 - Compounds of ruthenium, rhodium, palladium, osmium, iridium, or platinum

Abstract

To provide an electrode catalyst exhibiting high performance as a reversal-resistant anode catalyst in fuel cells.The above-described problem is solved by an electrode catalyst constituted by a composite catalyst obtained by mixing an iridium oxide (IrO2) nanosheet with a Pt/C catalyst as a promoter. A weight ratio (percentage) of the IrO2 nanosheet to a sum of the Pt/C and the IrO2 nanosheet is preferably within a range of 1% or more and 26% or less, and a Pt:Ir (atomic ratio) constituting the composite catalyst is preferably within a range of 1.5:1 to 50:1.Selected drawing: Fig. 1

IPC Classes  ?

• H01M 4/90 - Selection of catalytic material
• H01M 4/92 - Metals of platinum group
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

2222 is preferably within the range of 1-26% inclusive, and Pt:Ir (atomic ratio) constituting the composite catalyst is preferably within the range of 1.5:1-50:1.

IPC Classes  ?

• H01M 4/90 - Selection of catalytic material
• H01M 4/92 - Metals of platinum group
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

The present invention provides a method for producing chimeric antigen receptor T (CAR-T) cells, the method comprising a step for isolating, by means of beads, T cells from a T cell supply source using a specific factor. The specific factor is CD45RA+ or the like. The method enables production of CAR-T cells having high anti-tumor activity, and enables production of highly-functional CAR-T cells easily in a short period of time at a low cost.

IPC Classes  ?

• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

[Problem] To provide a method for producing a dielectric film using a polymeric material and an organic compound having a polar group. [Solution] A method for producing a dielectric film, comprising a step in which a polymeric material and an organic compound having a polar group are dissolved in a solvent to prepare a mixture solution including the polymeric material and the organic compound having a polar group, a step in which the mixture solution is applied to a substrate, and a step in which the polymeric material applied to the substrate is cured to form a thin film, the method being characterized in that the mixture solution is prepared so that the cured thin film has an inner structure composed of separated phases which are a continuous phase comprising the polymeric material and a dispersed phase consisting mainly of the organic compound having a polar group.

IPC Classes  ?

• C08K 5/315 - Compounds containing carbon-to-nitrogen triple bonds
• C08L 83/04 - Polysiloxanes
• C08L 101/00 - Compositions of unspecified macromolecular compounds
• H01B 3/28 - Insulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of organic substances natural or synthetic rubbers
• C08J 5/18 - Manufacture of films or sheets
• H01L 41/09 - Piezo-electric or electrostrictive elements with electrical input and mechanical output
• H01L 41/193 - Macromolecular compositions

Abstract

A dielectric film for a film capacitor includes (A) a thermoplastic resin and (B) a metal diketone complex.

IPC Classes  ?

• C08K 5/07 - AldehydesKetones
• H01G 4/32 - Wound capacitors
• H01G 4/38 - Multiple capacitors, i.e. structural combinations of fixed capacitors
• H01G 2/02 - Mountings
• H01G 4/33 - Thin- or thick-film capacitors
• H02M 7/5387 - Conversion of DC power input into AC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only, e.g. single switched pulse inverters in a bridge configuration
• H02P 27/06 - Arrangements or methods for the control of AC motors characterised by the kind of supply voltage using variable-frequency supply voltage, e.g. inverter or converter supply voltage using DC to AC converters or inverters
• C08K 3/11 - Compounds containing metals of Groups 4 to 10 or of Groups 14 to 16 of the Periodic Table
• B60L 50/60 - Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells using power supplied by batteries

Abstract

An insulating resin includes (A) a thermoplastic resin and (B) a metal diketone complex.

IPC Classes  ?

• C08K 5/07 - AldehydesKetones

Abstract

A method for regenerating a lithium composite oxide, which is an active material of a deteriorated lithium ion secondary battery, comprising: a step in which a lithium composite oxide is recovered from a deteriorated lithium ion secondary battery; and a step in which the recovered lithium composite oxide is mixed with a lithium source and a flux source so that the crystal of the lithium composite oxide is grown by a flux method.

IPC Classes  ?

• H01M 10/54 - Reclaiming serviceable parts of waste accumulators
• C01G 53/00 - Compounds of nickel

Abstract

Disclosed is a top layer for a light absorption surface, which comprises a matrix and nanoparticles embedded therein. The top layer may constitute the outermost layer of a solar absorber coating or absorber material surface, for use in solar heat power generation. The top layer may be able to enhance light absorption and accommodate the thermal expansion/contraction of the absorption coating or that of its underlying substrate in use. The nanoparticles embedded in, or adhered to the matrix, may contribute to the light absorption of the underlying absorption surface.

IPC Classes  ?

• F24S 70/20 - Details of absorbing elements characterised by absorbing coatingsDetails of absorbing elements characterised by surface treatment for increasing absorption
• F24S 70/30 - Auxiliary coatings, e.g. anti-reflective coatings
• F24S 70/60 - Details of absorbing elements characterised by the structure or construction

Abstract

The present invention addresses the problem of providing a novel composition having the effect of improving a mental state. The present invention pertains to: a composition that is for improving a mental state, and that contains, as an active ingredient, a water-soluble component of the fruit of eggplant (Solanum melongena); and a production method that is for an eggplant-derived composition for improving a mental state, and that comprises squeezing an eggplant fruit to obtain a juice, or adding water to an eggplant fruit and squeezing the fruit to which water has been added, to obtain a juice.

IPC Classes  ?

• A61K 36/81 - Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
• A61P 25/22 - Anxiolytics

Abstract

The present invention provides nanometer-sized fibers that are produced by an electrospinning method with use of a spinning solution for electrospinning, said spinning solution being environmentally friendly and taking the effects of an organic solvent on the human body into consideration. The fibers are formed from a resin that contains a silicone-modified polyurethane resin which is a reaction product of (A) a polyol, (B) a water dispersant, (C) an active hydrogen group-containing organopolysiloxane represented by formula (1) The present invention provides nanometer-sized fibers that are produced by an electrospinning method with use of a spinning solution for electrospinning, said spinning solution being environmentally friendly and taking the effects of an organic solvent on the human body into consideration. The fibers are formed from a resin that contains a silicone-modified polyurethane resin which is a reaction product of (A) a polyol, (B) a water dispersant, (C) an active hydrogen group-containing organopolysiloxane represented by formula (1) R1R2R3SiO(SiR2R3O)nSiR1R2R3  (1) The present invention provides nanometer-sized fibers that are produced by an electrospinning method with use of a spinning solution for electrospinning, said spinning solution being environmentally friendly and taking the effects of an organic solvent on the human body into consideration. The fibers are formed from a resin that contains a silicone-modified polyurethane resin which is a reaction product of (A) a polyol, (B) a water dispersant, (C) an active hydrogen group-containing organopolysiloxane represented by formula (1) R1R2R3SiO(SiR2R3O)nSiR1R2R3  (1) (wherein R1 represents a monovalent hydrocarbon group which may have an oxygen atom in the chain, while having from 1 to 10 carbon atoms and a hydroxyl group or a mercapto group, or a monovalent hydrocarbon group which has a primary amino group or a secondary amino group, while having from 1 to 10 carbon atoms; each of R2 and R3 represents a group that is selected from among an alkyl group having from 1 to 10 carbon atoms, an aralkyl group having from 7 to 10 carbon atoms, an aryl group having from 6 to 12 carbon atoms and a vinyl group; and n represents an integer from 1 to 200), and (D) a polyisocyanate.

IPC Classes  ?

• C08G 18/77 - Polyisocyanates or polyisothiocyanates having hetero atoms in addition to the isocyanate or isothiocyanate nitrogen and oxygen or sulfur
• C08G 18/61 - Polysiloxanes
• D01F 6/70 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolycondensation products from polyurethanes
• D01D 5/00 - Formation of filaments, threads, or the like
• D04H 1/4358 - Polyurethanes
• D04H 1/728 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning

Abstract

A determination device 1 is provided with: an acquisition unit 21 for acquiring digital color image data 11 about a region of interest in melanonychia striata in a subject; a calculation unit 23 for calculating an index value 12 from the variation in RGB values of the individual pixels in the digital color image data 11; and an output unit 24 for outputting such a result that the melanonychia striata is determined as malignant when the index value 12 is larger than a threshold value and the melanonychia striata is determined as benign when the index value 12 is smaller than the threshold value.

IPC Classes  ?

• A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

Provided is a production method which makes it possible to improve a filling property, with respect to a resin, of a hexagonal boron nitride powder which contains hexagonal boron nitride particles each having a low aspect ratio, while maintaining low thermal conduction anisotropy of the hexagonal boron nitride powder. A method of producing a hexagonal boron nitride powder includes disintegrating, by a means which substantially does not involve pulverization of primary particles, a hexagonal boron nitride raw material powder which contains (i) hexagonal boron nitride particles each having an aspect ratio of 1.5 to 5.0 and (ii) an aggregate that contains hexagonal boron nitride particles each having an aspect ratio of more than 5.0.

IPC Classes  ?

• C01B 21/064 - Binary compounds of nitrogen with metals, with silicon, or with boron with boron
• C08K 3/38 - Boron-containing compounds

Abstract

Single crystalline nanoparticles that are tantalum nitride doped with at least one metal are described. The single crystalline nanoparticles can be doped with two metals such as Zr and Mg. The single crystalline nanoparticles can be TasNsMg+Zr, or TasNsMg, or TasNs:Zr or any combination thereof. Catalyst containing the single crystalline nanoparticles alone or with one or more co-catalyst are further described along with methods of making the nanoparticles and catalyst. Methods to split water utilizing the catalyst are further described.

IPC Classes  ?

• B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
• B01J 21/10 - MagnesiumOxides or hydroxides thereof
• B01J 23/42 - Platinum
• B01J 23/648 - Vanadium, niobium or tantalum
• B01J 27/24 - Nitrogen compounds
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 35/02 - Solids
• B01J 35/06 - Fabrics or filaments
• B01J 37/02 - Impregnation, coating or precipitation
• B01J 37/08 - Heat treatment
• B01J 37/16 - Reducing
• B01J 37/18 - Reducing with gases containing free hydrogen
• B01J 37/34 - Irradiation by, or application of, electric, magnetic or wave energy, e.g. ultrasonic waves

Abstract

Provided is a nanocellulose master batch that can be used to obtain a rubber composition in which nanocellulose is homogenously dispersed and which has excellent tensile stress and stretchability. This nanocellulose master batch contains a rubber component, a nanocellulose that is surface-treated with at least one selected from the group consisting of phenolic resins, epoxy resins, urethane resins, and melamine resins, and a water-soluble polymer. In the nanocellulose master batch, the nanocellulose is contained in an amount of 0.3-15 parts by mass with respect to 100 parts by mass of the rubber component, and the water-soluble polymer is contained in an amount of 0.03-1.2 parts by mass with respect to 1 part by mass of the nanocellulose.

IPC Classes  ?

• C08L 21/00 - Compositions of unspecified rubbers
• C08J 3/205 - Compounding polymers with additives, e.g. colouring in the presence of a liquid phase
• C08K 3/04 - Carbon
• C08K 3/36 - Silica
• C08K 9/04 - Ingredients treated with organic substances
• C08L 1/00 - Compositions of cellulose, modified cellulose, or cellulose derivatives
• C08L 101/14 - Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels

Abstract

What is provided is a layered double hydroxide crystal for achieving higher ion-exchange capacity than that of the related art. What is provided is a layered double hydroxide crystal for achieving higher ion-exchange capacity than that of the related art. The layered double hydroxide crystal 1 according to the present embodiment is represented by Formula (1) and composed of a plurality of crystal grains 10 each of which has a lamination structure in which a plurality of plate-shaped crystals (11), (11), . . . are laminated, in which particle sizes of the plurality of crystal grains (10), (10), . . . are uniform on a microscale. What is provided is a layered double hydroxide crystal for achieving higher ion-exchange capacity than that of the related art. The layered double hydroxide crystal 1 according to the present embodiment is represented by Formula (1) and composed of a plurality of crystal grains 10 each of which has a lamination structure in which a plurality of plate-shaped crystals (11), (11), . . . are laminated, in which particle sizes of the plurality of crystal grains (10), (10), . . . are uniform on a microscale. [Ni2+1-xFe3+x(OH)2].[(Cl−)X/2]  (1) (Where, 0.25

IPC Classes  ?

• C02F 1/42 - Treatment of water, waste water, or sewage by ion-exchange
• B01J 41/10 - Inorganic material
• C30B 9/04 - Single-crystal growth from melt solutions using molten solvents by cooling of the solution

Abstract

This carbon nanotube structure, in which a plurality of carbon nanotubes are assembled, has: joining portions between end portions and end portions of the carbon nanotubes; and joining portions between end portions and side wall portions of the carbon nanotubes.

IPC Classes  ?

• C01B 32/168 - After-treatment

Abstract

xyzz (wherein, 0

IPC Classes  ?

• B01J 39/10 - Oxides or hydroxides
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C02F 1/42 - Treatment of water, waste water, or sewage by ion-exchange
• B01J 20/06 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group
• B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
• B01J 20/30 - Processes for preparing, regenerating or reactivating

Abstract

klm21-zklm2-xxx(k+l+m=1, k≧0.6, z≦0.62, 0

IPC Classes  ?

• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy

Abstract

A magnetic field sensor element 1 includes a light emitter 10 emitting a first linearly polarized light, a first optical element 20 emitting a first linearly polarized wave and the second linearly polarized wave in response to a first linearly polarized light incident, and emitting a second linearly polarized light in response to a third linearly polarized wave and the a linearly polarized wave incident, at least one pair of magnetic field sensor elements 50 capable of disposing in a predetermined magnetic field across the measured conductor, having a light transmissive, changing the phase of transmitted light in accordance with the magnetic field, and fixing a relative position therebetween, an optical path 30 including a first optical path propagating the first linearly polarized wave and the fourth linearly polarized wave, and a second optical path propagating the second linearly polarized wave and the third linearly polarized wave, and connected to the first optical element and the magnetic field sensor element, a detected signal generator 60 outputting a detected signal corresponding to the magnetic field, by receiving two components of the second linearly polarized light, and converting to the electrical signal, and an optical branching element transmitting the first linearly polarized light to the first optical element and branching the second linearly polarized light to the detected signal generator.

IPC Classes  ?

• G01R 15/24 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using light-modulating devices
• G01R 33/032 - Measuring direction or magnitude of magnetic fields or magnetic flux using magneto-optic devices, e.g. Faraday

Abstract

The present disclosure includes a method of producing a cell population containing Chimeric Antigen Receptor (CAR)-expressing immune cells, comprising co-culturing CAR-expressing immune cells and cells expressing a target antigen of the CAR, wherein the CAR-expressing immune cells are cells into which a CAR gene has been introduced and the target antigen-expressing cells are normal blood cells that have been engineered to express the target antigen.

IPC Classes  ?

• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• A61P 35/00 - Antineoplastic agents
• C07K 14/715 - ReceptorsCell surface antigensCell surface determinants for cytokinesReceptorsCell surface antigensCell surface determinants for lymphokinesReceptorsCell surface antigensCell surface determinants for interferons
• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes

Abstract

The present invention is intended to develop a chimeric antigen receptor (CAR) that is effective against solid tumor expressing anaplastic lymphoma kinase (ALK). The present invention provides a polynucleotide encoding a CAR protein comprising a target binding domain binding to an extracellular ligand binding region of ALK, a transmembrane domain, and an intracellular signaling domain. The target binding domain of the polynucleotide is selected from among FAM150A, FAM150B, and fragments thereof binding to the extracellular ligand binding region of ALK. The present invention also provides a genetically modified cell comprising the polynucleotide introduced thereinto.

IPC Classes  ?

• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• C12N 15/62 - DNA sequences coding for fusion proteins
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C07K 14/725 - T-cell receptors
• A61P 35/00 - Antineoplastic agents

Abstract

Provided is a novel and/or improved means for immunostimulation. A composition, a food or beverage, an animal feed or a medicine, each comprising a resistant protein having an immunostimulatory effect. The immunostimulatory effect is to induce interferon gamma production by immunocytes. The immunocytes are spleen cells.

IPC Classes  ?

• A61P 37/04 - Immunostimulants
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
• A23L 33/17 - Amino acids, peptides or proteins
• A61K 38/02 - Peptides of undefined number of amino acidsDerivatives thereof

Abstract

A production apparatus for a metal oxide single crystal according to one aspect of the present invention includes: a furnace having an interior heated to a temperature of 1,500° C. or more in an oxidative atmosphere, a heater heating the interior of the furnace, an inlet pipe being disposed in a lower part of the furnace and connecting an interior and an exterior of the furnace, an exhaust pipe being disposed in an upper part of the furnace and connecting an interior and an exterior of the furnace, a duct being disposed above the furnace, and an exhaust fan and a harmful substance elimination device being disposed in the middle of the duct.

IPC Classes  ?

• C30B 11/00 - Single-crystal-growth by normal freezing or freezing under temperature gradient, e.g. Bridgman- Stockbarger method
• C30B 29/16 - Oxides

Abstract

An identification device includes an acquirer for acquiring a captured image obtained by imaging a predetermined target, a specifier for specifying a linear region extending in a plurality of mutually different directions, from a region of the captured image acquired by the acquirer, the region including the predetermined target, and an extractor for extracting a feature quantity based on the pixel value, from the linear region specified by the specifier.

IPC Classes  ?

• G06V 10/20 - Image preprocessing
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• G06T 7/00 - Image analysis
• G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]

Abstract

A method for producing boron nitride, said method comprising a step for obtaining melamine borate and a firing step for firing the melamine borate in the presence of a flux at a temperature of 1000-1700°C inclusive to give boron nitride.

IPC Classes  ?

• C01B 21/064 - Binary compounds of nitrogen with metals, with silicon, or with boron with boron

Abstract

An oxygen isotope separation method that separates 1822 and 1622, said method comprising: an adsorption step in which a gas mixture containing 1822 and 1622 is passed through an adsorbent that is -143°C or less, thereby causing the 1822 to be adsorbed onto the adsorbent and storing unadsorbed gas in a first tank; and a desorption step in which the temperature of the adsorbent is increased, thereby desorbing the gas adsorbed onto the adsorbent and storing the gas in a second tank, wherein the average pore size of the adsorbent determined using nitrogen adsorption measurement is 0.35-0.7 nm.

IPC Classes  ?

• B01D 59/26 - Separation by extracting by sorption, i.e. absorption, adsorption, persorption
• B01J 20/18 - Synthetic zeolitic molecular sieves

Abstract

Provided are: a cell culture member having excellent cell culture performance and long-term stability thereof; and a surface modification method therefor. The present invention makes it possible to provide a cell culture member in which the adhesion of adhesive cells to a surface modified area is improved, deterioration of the adhesion over time is reduced, and the cell culture performance and long-term stability thereof are excellent. A cell culture member according to the present invention, in which a holding area for at least adhesive cells comprises a polymer compound, is characterized in that at least part of the holding area is a surface modified area in which a functional group including a nitrogen atom is directly chemically bonded to some carbon atoms and/or silicon atoms constituting the polymer compound.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus

Abstract

Provided are: a cell culturing member which has excellent cell culturing performance and has long-term stability of the cell culturing performance; and a method for modifying the surface of the cell culturing member. The cell culturing member according to the present invention is one in which at least an adhesive cell holding region comprises a polymeric compound, the cell culturing member being characterized in that at least a portion of the holding region is a surface modified region in which a fluorine atom is chemically bound directly to each of some of carbon atoms and/or silicon atoms constituting the polymeric compound. It becomes possible to provide a cell culturing member in which the adhesiveness of adhesive cells to the surface modified region is improved, the deterioration in this adhesiveness over time is prevented, and cell culturing performance and the long-term stability of the cell culturing performance are excellent.

IPC Classes  ?

• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C08J 7/12 - Chemical modification

Abstract

The present disclosure provides a carbon material including a carbon-containing layer having opening parts; and a solid body provided so as to cover the opening parts of the carbon-containing layer, in which the solid body has hole parts communicating with the opening parts.

IPC Classes  ?

• B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
• B01D 71/02 - Inorganic material
• C01B 32/178 - OpeningFilling
• C01B 32/194 - After-treatment
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

The present invention addresses the problem of providing, by a method in which an expensive manufacturing apparatus is not required, an implant material having osteoconductivity superior to that of an implant material containing an aromatic polyether ketone. The present invention pertains to: said method including immersing an aromatic polyether ketone in a strong base solution in the absence of a calcium ion, and immersing an aromatic polyether ketone, which is obtained by the immersing, in a liquid containing a phosphorus-containing compound; and an implant material obtained by said method.

IPC Classes  ?

• A61L 27/32 - Phosphorus-containing materials, e.g. apatite
• A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• A61L 27/34 - Macromolecular materials
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• C08G 65/48 - Polymers modified by chemical after-treatment
• C08G 65/40 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives derived from phenols from phenols and other compounds
• C08J 7/14 - Chemical modification with acids, their salts or anhydrides

Abstract

A cryptographic communication system includes: a first cryptographic communication apparatus including a first tamper-resistant device configured to store a first key generation function and a first storage unit configured to store first individual information; and a second cryptographic communication apparatus including a second tamper-resistant device configured to store a second key generation function and a second storage unit configured to store second individual information. The first cryptographic communication apparatus generates a twelfth shared key using the first key generation function and the second individual information. The second cryptographic communication apparatus generates a twenty first shared key using the second key generation function and the first individual information.

IPC Classes  ?

• H04L 29/06 - Communication control; Communication processing characterised by a protocol
• H04L 9/40 - Network security protocols
• H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
• H04L 9/08 - Key distribution

Abstract

Provided are: a trisubstituted benzene compound represented by general formulae (1) and (2); and an organic electroluminescence (EL) element having a pair of electrodes and at least a pair of organic layers interposed therebetween, the organic EL element being characterized in that said compound is used as a constituent material for at least one organic layer. Provided are: a trisubstituted benzene compound represented by general formulae (1) and (2); and an organic electroluminescence (EL) element having a pair of electrodes and at least a pair of organic layers interposed therebetween, the organic EL element being characterized in that said compound is used as a constituent material for at least one organic layer.

IPC Classes  ?

• C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
• C07D 493/00 - Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
• C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings

Abstract

In order to search for a functional substance that selectively binds to a non-native structure of a protein and that affects the function of the protein, the present invention involves: destabilizing, at least partially, a protein; providing the destabilized protein in the presence of a functional substance candidate; promoting re-stabilization of the protein; and determining the effect on the function of the protein in the presence of the functional substance candidate.

IPC Classes  ?

• C12Q 1/42 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving phosphatase
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

A filter material that includes sodium titanate, adsorbs the heavy metal cations contained in aqueous solutions, and satisfies expression (A). (A) 0 cps·deg

IPC Classes  ?

• C01G 23/00 - Compounds of titanium
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• B01J 20/06 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• B01J 20/30 - Processes for preparing, regenerating or reactivating

Abstract

The positive electrode according to the present invention is a positive electrode of a lithium-ion secondary cell obtained by pressing a coating containing a positive electrode active material onto the surface of a positive electrode substrate, the positive electrode active material being a mixture of a first active material formed from single particles of a lithium composite oxide and a second active material formed from secondary particles in which single particles of a lithium composite oxide are aggregated.

IPC Classes  ?

• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids

Abstract

A pharmaceutical composition including particles each containing a water-soluble base material and a poorly water-soluble compound, the water-soluble base material containing a rapidly water-soluble compound, wherein the poorly water-soluble compound is a kinase inhibitor and exists in an amorphous state in the water-soluble base material.

IPC Classes  ?

• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets

Abstract

To set a scale for three dimensional data composed from point cloud data: a plurality of reference objects (22) of sizes and shapes known in advance are disposed around an object (20) under measurement; image data or position data obtained by imaging the object (20) under measurement together with the plurality of reference objects (22) from various angles is input to a computer (30); the known sizes and shapes of the reference objects (22) are input to the computer (30); and the computer (30) acquires point cloud data for the object (20) under measurement and each reference object (22) from a plurality of pieces of the image data or a plurality of pieces of the position data, determines, as reference objects, objects in the point cloud data having sizes and shapes within prescribed error ranges with respect to the sizes and shapes input for the reference objects (22), and sets the overall scale of the point cloud data by extending/contracting and/or twisting the point cloud data such that each of the determined reference objects has the input size and shape.

IPC Classes  ?

• G01B 11/00 - Measuring arrangements characterised by the use of optical techniques

Abstract

According to one embodiment, a composition is for delivering an objective substance to the T-cell malignant tumor cell. The composition contains a substance delivery carrier. The substance delivery carrier has a lipid particle, and the objective substance encapsulated in the lipid particle. The lipid particle contains, as constituents thereof, at least a first lipid represented by formula (I) and a second lipid represented by formula (II).

IPC Classes  ?

• A61K 9/50 - Microcapsules
• A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

Abstract

2/g. The hexagonal boron nitride primary particles each have a long diameter of not less than 0.6 μm and not more than 4.0 μm and an aspect ratio of not less than 1.5 and not more than 5.0.

IPC Classes  ?

• C01B 21/064 - Binary compounds of nitrogen with metals, with silicon, or with boron with boron
• C08K 3/38 - Boron-containing compounds
• C08L 101/00 - Compositions of unspecified macromolecular compounds