Butters are a specific class of cosmetic triglycerides that provide a unique feel on skin. There are very few such materials in nature. In order for a butter to be of interest to the personal care market, it must be (1) soft at room temperature; (2) must not “crack” when handled; (3) must be able to be applied to the skin at ambient temperature by rubbing; (4) must liquefy upon rubbing, (5) must be free of rancidity and (6) must be free of trans acids that are the result of partial hydrogenation. For unsaturated oils to be made into butters, partial hydrogenation is the most common approach. This results in the formation of trans acids which are highly undesirable.
The present invention discloses a series of non-hydrogenated butters made by a process referred to as totally randomized triglycerides. The butters are made using a very specific range of very specific types and ratios of fatty acids to glycerin to provide the highly desirable cosmetic butters meeting the requirements 1-5 above.
The present invention is directed toward a series of polyesters synthesized utilizing propane diol with tunable ascetics and performance in cosmetic formulation. These novel propane diol polyesters are designed to have great esthetics in cosmetic formulation. The physical properties and aesthetics of the current invention can be tuned rapidly by controlling the fatty groups, as well as the molecular weight of the polymer. The resulting propane diol polyesters have outstanding aesthetics and physical properties.
The present invention is directed to a series of silicone containing polymers that contain photostabilizers that act as photo stabilizers for Ultra Violet radiation. The polymers of the present invention are multi functional sun-screening additives that allow in addition to photostabilizing the active sunscreen agent found in sunscreens, additionally provide high levels of UV protection in a cosmetically elegant base. The compounds are made by the reaction of a benzatriazole compound and a methyl ester silicone compound.
The present invention is directed to a series of glycerin based polymers that have been designed to have very specific substitution patterns, herein referred to as regiospecific substitution (RSS). The attachment of terminal mono-functional silicone polymers engineered polyesters of glycerin results in heretofore unrecognized products. The unique properties include lower surface tension, better spreadability and a dry skin feel, all of which cannot be attained without the use of a terminal silicone. Incorporation of silicone into the terminal position requires a very specific synthesis regime to establish the sought after regiospecificity.
The present invention is directed to a series of glycerin polysilicones. By glycerin polysilicones in meant polymers that have silicone portions that are functionalized with glycerin groups. The polymers of the present invention can range from relatively low molecular weight (around 600 daltons) to higher molecular weight (of about 2,500 daltons). The presence of the glyceryl groups together with the silicone groups allows for the preparation of molecules uniquely suited to personal care applications, more specifically, skin care products.
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient
A61K 8/58 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
The present invention is directed to a series of citrate ester emulsifiers that are effective in making water in oil (regular emulsions) and oil in water (invert emulsions) and contain a silicone portion that provides better spreadability and skin aesthetics. In addition to being outstanding emulsifiers, these emulsifiers provide unique solubility, liquidity and outstanding feel when applied to the skin, making them highly desirable in cosmetic emulsions.
The present invention is directed to a series of polyesters that are made by the reaction of a diacid with a pre-formed mono-hydroxy, di-hydroxy and optionally a tri-hydroxy ester of polyols selected from pentaerythritol, di pentearythritol trimethylolpropane and mixtures thereof. When reacted in the sequence shown, that is pre-formation of the mono-ester, di-ester and tri-ester, selection of the proper ratio of one to the other and then and only then reacted with the diacid, do these polyesters remain free of a gel and form cosmetically elegant oil phases.
C08G 63/553 - Acids or hydroxy compounds containing cycloaliphatic rings, e.g. Diels-Alder adducts
C08G 63/676 - Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation
C08G 63/199 - Acids or hydroxy compounds containing cycloaliphatic rings
C08G 63/12 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
C08G 63/16 - Dicarboxylic acids and dihydroxy compounds
C08G 63/137 - Acids or hydroxy compounds containing cycloaliphatic rings
A61K 8/72 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
The present invention is directed to a series of silicone containing polymers that contain photostabilizers that act as photo stabilizers for Ultra Violet radiation. The polymers of the present invention are multi functional sun screening additives that allow in addition to photostabilizing the active sunscreen agent found in sunscreens, additionally provide high levels of UV protection in a cosmetically elegant base. The photostabilizing compositions are derived from a tricarboxylic triazine compound.
The present invention is directed to ester compositions which result from the trans-esterification of a triglyceride having an iodine value of between 85 and 175 mg KOH/gm with a fatty alcohol having a melting point of between 35° and 75° C., followed by cooling and removal of the polar phase which results. Surprisingly, we have found the composition has unique properties when used in cosmetic applications.
The present invention is directed toward a series of polyesters synthesized utilizing propane diol with tunable ascetics and performance in cosmetic formulation. These novel propane diol polyesters are designed to have great esthetics in cosmetic formulation. The physical properties and aesthetics of the current invention can be tuned rapidly by controlling the fatty groups, as well as the molecular weight of the polymer. The resulting propane diol polyesters have outstanding aesthetics and physical properties.
A01N 37/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
C07C 69/74 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
The present invention is aimed at a series of novel glycerin polyesters that provide desired aesthetics and structure in cosmetic formulation. These glycerin polymers are synthesized by polycondensation polymerization, in the presence of a monofunctional monomer or terminal group. By carefully choosing the groups the properties can be dramatically altered. The mono-functional alcohols, being only able to react in one position, can only be located on the polymer chain ends. This provides very unique polymer structure and morphology. These regiospecific polyesters will have very unique physical properties and have a wide variety of solubilities. Furthermore, by the incorporation of a co-monomer will produce a copolymer with drastically different solubilities and aesthetics.
The present invention is directed to a series of citrate ester emulsifiers that are effective in making water in oil (regular emulsions) and oil in water (invert emulsions). In addition to being outstanding emulsifiers, these emulsifiers provide unique solubility, liquidity and outstanding feel when applied to the skin, making them highly desirable in cosmetic emulsions.
C07C 69/66 - Esters of carboxylic acids having esterified carboxyl groups bound to acyclic carbon atoms and having any of the groups OH, O-metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
C08K 5/11 - EstersEther-esters of acyclic polycarboxylic acids
The present invention has as its objective a series of citrate polyesters that have based upon fatty alcohols reacted with citric acid, and crosslinked by water soluble diols, resulting in polymers with improved water solubility. These polymers are ideally suited to personal care applications due to their unique feel delivered from aqueous solution or emulsions.
The present invention is directed toward a series of polyglycerol silicone polyesters with tunable ascetics and performance in cosmetic formulation. These novel polyglycerol silicone polyesters are designed to be high definition polymers. High Definition Polymers is meant that the polymer contains a variety of groups containing different chemical and physical properties that can be controlled by the polymerization process. High definition polymers are polymers are synthesized to have each portion of the polymer to achieve a desired aesthetics. These high definition polymers physical properties can be tuned quickly and easily but the polymerization conditions. The physical properties of the current invention can be tuned rapidly by controlling the ratio of fatty groups, as well as the cross-linker used. The resulting polyglycerol silicone polyesters have outstanding aesthetics, unique solubility and physical properties.
The present invention is directed toward a series of polyglycerol polyesters that have silicone terminal groups with tunable ascetics and performance in cosmetic formulation. These novel silicone containing polyglycerol polyesters are designed to be multidimensional. Multidimensional is meant that the polymer contains a variety of groups containing different chemical and physical properties covalently bonded together. The physical properties of the current invention can be tuned rapidly by controlling the ratio of fatty groups, as well as the cross-linker used. Tuned here is meant the ability to adjust the physical properties to a desired value. The resulting polyglycerol polyesters have outstanding aesthetics and physical properties.
The present invention is directed to a series of functionalized glycerin based polymers that have been designed to have very specific substitution patterns, herein referred to as regio-specific substitution (RSS). The properties of these polymers can be controlled and tuned by judicial control of the polymerization conditions, specifically by employing the use of mono-functional monomers. This polymer will has “compartments” of solid and liquid pendant group domains if the proper pendant groups are chosen. This unique multi-dimensional, high definition polymer will have very unique physical properties, including unique shear and flow behaviors. These polymers will provide outstanding and unique skin feels when used in cosmetic applications.
The present invention is directed to a series of polymeric citrate esters that has very unique rheology properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film and flow properties. These compounds by virtue of their unique structure provide outstanding skin feel and outstanding waterproof properties in cosmetic formulations most notable sunscreens.
C08G 63/60 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from the reaction of a mixture of hydroxy carboxylic acids, polycarboxylic acids and polyhydroxy compounds
The present invention is directed toward a series of silicone/organic polymers with tunable ascetics, solubility, film formation and performance in cosmetic formulation. These novel polymers are designed with the three different hydroxyl containing monomers in the polyester. One is a siliphillic (silicone loving) and the other a oleophillic (oil loving) and the last hydrophilic (water loving). It is critical for there to be all three types of monomers linked together in a single polymer in order to make polymers in which solubility, spreadability, surface tension and film hardness can be altered for different cosmetic applications. When these groups are present a polymer there is a wide range of variation possible, making these polymers formulator friendly. The physical and chemical properties, including but not limited to: film formation of the current invention can be tuned rapidly by controlling the fatty group used, the degree of polymerization of the polymer, the molecular weight of the silicone polymer, the presence of ethylene oxide in the polymer backbone and the ratio of monomers to one another.
The present invention is directed to a series of silicone containing polymeric glyceryl esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, but has very unique flow properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel.
The present invention is directed to a series of citrate ester emulsifiers that are effective in making water in oil (regular emulsions) and oil in water (invert emulsions). In addition to being outstanding emulsifiers, these emulsifiers provide unique solubility, liquidity and outstanding feel when applied to the skin, making them highly desirable in cosmetic emulsions.
C07C 69/66 - Esters of carboxylic acids having esterified carboxyl groups bound to acyclic carbon atoms and having any of the groups OH, O-metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
The present invention is directed to a series of glycerin based polymers that have been designed to have very specific substitution patterns, herein referred to as regiospecific substitution (RSS). The attachment of terminal mono-functional silicone polymers engineered polyesters of glycerin results in heretofore unrecognized products. The unique properties include lower surface tension, better spreadability and a dry skin feel, all of which cannot be attained without the use of a terminal silicone. Incorporation of silicone into the terminal position requires a very specific synthesis regime to establish the sought after regiospecificity.
C08G 63/02 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds
C08G 77/14 - Polysiloxanes containing silicon bound to oxygen-containing groups
C08G 63/12 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
C08G 77/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon
C08G 63/91 - Polymers modified by chemical after-treatment
C08G 63/695 - Polyesters containing atoms other than carbon, hydrogen, and oxygen containing silicon
The present invention is directed to a series of silicone containing polymeric glyceryl esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, but has very unique flow properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel.
The present invention is directed to a series of polymeric glyceryl esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, but has very unique flow properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel.
A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
A01N 37/02 - Saturated carboxylic acids or thio-analogues thereofDerivatives thereof
C08G 63/54 - Polycarboxylic acids or polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation the acids or hydroxy compounds containing carbocyclic rings
The present invention is directed toward a series of polyesters with tunable ascetics and skin conditioning properties for use in cosmetic formulation, specifically sun screening formulations in which the performance is improved by a synergistic effect between the sunscreening actives and the polyester. These novel polyglycerol polyesters are designed to be multidimensional. The physical properties and aesthetics of the current invention can be tuned rapidly by controlling the ratio of fatty groups, as well as the cross-linker used. The resulting polyglycerol polyesters have outstanding aesthetics and physical properties.
The present invention provides a method for diagnosing a particular type of human hepatocellular carcinoma (HCC), HBx/8p11-positive HCC, in a subject by detecting the presence of a specific, non-naturally occurring polynucleotide sequence that indicates integration of a portion of the human hepatitis B virus (HBV) sequence into the human genome on chromosome 8 in the 8p11 integration region. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for treating an HBx/8p11-positive HCC.
The present invention is directed to a series of polymeric glyceryl esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, and crosslinked by dimer acid. These products have very unique skin feel and water proofing properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel.
A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
A61K 8/72 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
A61K 8/84 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions other than those involving only carbon-to-carbon unsaturated bonds
C08G 63/54 - Polycarboxylic acids or polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation the acids or hydroxy compounds containing carbocyclic rings
The present invention has as its objective a series of citrate polyesters that have based upon guerbet alcohols reacted with citric acid, and crosslinked by diols. These polymers have a very low viscosity when one considers the molecular weight, and are ideally suited to personal care applications due to their unique feel.
C07C 69/347 - Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom esterified with unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
The present invention has as its objective a series of citrate polyesters that have based upon guerbet alcohols reacted with citric acid, and crosslinked by water soluble diols, resulting in polymers with improved water solubility. These polymers have a very low viscosity when one considers the molecular weight, and are ideally suited to personal care applications due to their unique feel delivered from aqueous solution or emulsions.
C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
C08G 63/12 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
The present invention is directed to a series of polymeric citrate esters that have unique liquidity, and outstanding feel when applied to the skin. The polymers of the present invention are made by polymerizing citrate mono and di fatty esters with a hydroxypropyl functional silicone to provide a polymer with a very low surface tension and outstanding skin feel.
The present invention relates to a series of polyglycoside derivatives that are (a) polymeric (that is cross linked with hydroxypropyl linkages) and (b) contain additional functional groups including alkoxy, sulfate, sulfonate, quaternary and phosphate groups, and (c) sorbitan esters to increase oil solubility and provide outstanding emulsifiers.
The present invention is directed to a series of polymeric citrate esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, but has very unique flow properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel and outstanding waterproof properties in cosmetic formulations most notable sunscreens.
The present invention is directed to a series of polymeric citrate esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, but has very unique flow properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel and outstanding waterproof properties in cosmetic formulations most notable sunscreens.
The present invention has as its objective a series of citrate polyesters that have based upon guerbet alcohols reacted with citric acid, and crosslinked by diols. These polymers have a very low viscosity when one considers the molecular weight, and are ideally suited to personal care applications due to their unique feel.
C07C 69/347 - Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom esterified with unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
The invention relates to a series of multifunctional polyglycosides derivatives that are made by the polymerized by the reaction of 1,3 dichloro isopropanl and polyglycosides, together with a functionalizing agent that contains a sulfate, sulfonate, quaternary nitrogen, or a phosphate group. The preferred polymers are cross linked having more than one group per molecule. They are made with mild reagents to avoid discoloration and mal odor.
The present invention is drawn to a process for providing emolliency to the skin using a series so called “spider esters”. These esters are derived from poly-hydroxy functional compounds sequentially reacted with ethylene oxide or propylene oxide, followed by the reaction of the alkoxylate with fatty acid. The resulting products are called spider esters because they resemble the spider, wherein appendages are alkoxylated esters. The restrictions this orientation imposes on rotation allows for the preparation of polar esters that have little or no water solubility, and provide both moisturization to the skin and emolliency by reducing transepidermal water loss.
The present invention is directed to a series of new cationic polymeric materials and a process for their use as moisturizing agents on skin. The polymers of the invention are made by the reaction of dimethyl ethanolamine, and tetra 2-hydroxyalkyl ethylene diamne with di-chloro glycerin in water.
C08G 73/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen, with or without oxygen or carbon, not provided for in groups
The invention relates to a series of multifunctional polyglycosides derivatives that are made by the polymerized by the reaction of polyoxyalkylene containing crosslinking reagent and polyglycosides, together with a functionalizing agent that contains a sulfate, sulfonate, quaternary nitrogen, or a phosphate group. The preferred polymers are cross linked having more than one group per molecule. They are made with mild reagents to avoid discoloration and mal odor.
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Silicone derivatives of acetylenic based compounds used as raw materials in the formulation of personal care and industrial products, namely, lubricants, emollients and conditioners
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Silicone derivatives of acetylenic based compounds used as raw materials in the formulation of personal care and industrial products, namely, lubricants, emollients and conditioners
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Fatty acid esters of glycerin, pentaerythritol, trimethyol propane and sorbitol and alkoxylates thereof used as raw materials in the formulation of emollients used in skin care applications
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
PERSONAL CARE COSMETICS AND SKIN CARE PRODUCTS NAMELY EXFOLIANTS, SCRUBS, PEELS, TONERS, MOISTURIZERS, AND EMOLLIENTS, ALL FOR TOPICAL APPLICATION TO THE SKIN; LOTIONS, GELS, CREAMS AND SERUMS FOR TREATMENT OF THE SKIN; FACIAL MASKS, INCLUDING HYDROGELS; NON-MEDICATED CREAMS, LOTIONS, GELS AND SPRAYS FOR THE PROTECTION OF THE SKIN AGAINST ULTRAVIOLET LIGHT RAYS
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
PERSONAL CARE COSMETICS AND SKIN CARE PRODUCTS NAMELY EXFOLIANTS, SCRUBS, PEELS, TONERS, MOISTURIZERS, AND EMOLLIENTS ALL FOR TOPICAL APPLICATION TO THE SKIN; LOTIONS, GELS, CREAMS AND SERUMS FOR TREATMENT OF THE SKIN; FACIAL MASKS, INCLUDING HYDROGELS; NON-MEDICATED CREAMS, LOTIONS, GELS AND SPRAYS FOR THE PROTECTION OF THE SKIN AGAINST ULTRAVIOLET LIGHT RAYS
