Abstract

351212, and a band gap energy of 3 eV or more. The metal element A includes at least one element that is selected from among trivalent rare earth elements, and the metal element B includes at least one element that is selected from among trivalent typical elements.

IPC Classes  ?

• H01G 7/02 - Electrets, i.e. having a permanently-polarised dielectric
• C04B 35/50 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on rare earth compounds

Abstract

Provided is a novel nucleotide monomer that has a nucleobase with an unsubstituted amino group and yields a nucleic acid oligomer at a high yield. Also provided is a method for producing the nucleic acid oligomer at a high yield.　The nucleotide monomer according to the present invention is represented by general formula (1). In the formula: R1represents a hydrogen atom or the like; R2represents a hydrogen atom; R1and R2are bonded to each other to form a prescribed 5-member or higher ring; R3is a hydrogen atom or a protecting group of a hydroxyl group; R4is an aryl group having or not having a substituent; R5is a hydrogen atom or the like and R6represents an alkyl group of three or more carbons, the alkyl group having or not having a substituent, and having or nor having a heteroatom in the molecular chain, or R5and R6are bonded to each other to form a prescribed 5-member or higher ring having a branched chain; BNH2represents a nucleobase that is adenine A, guanine G, cytosine C, 5-methylcytosine mC, thymine, or uracil; and the amino group in A, G, C, and mC is not substituted.

IPC Classes  ?

• C07H 19/11 - Pyrimidine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids containing cyclic phosphate
• C07H 19/213 - Purine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids containing cyclic phosphate
• C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• C07H 23/00 - Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Abstract

A liquid circulation system according to an aspect of the present disclosure is for recovering an ionic liquid supplied into a vacuum chamber and returning the recovered ionic liquid back again into the vacuum chamber, and includes a storage tank having an opening communicating with an inside of the vacuum chamber and configured to store the ionic liquid recovered from the inside of the vacuum chamber through the opening, a viscosity pump provided below the storage tank in a vertical direction, and a pipe configured to supply the ionic liquid inside the storage tank into the vacuum chamber.

IPC Classes  ?

• H01L 21/67 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components

Abstract

2222 phase are both less than 0.1% by mass as quantitative values obtained by Rietveld analysis on the powder X-ray diffraction pattern; and a method for manufacturing the same. Also provided are: a thermoelectric conversion element which uses the above-described thermoelectric conversion molten synthetic body or the thermoelectric conversion sintered body; and a thermoelectric conversion module which is provided with the thermoelectric conversion element.

IPC Classes  ?

• H10N 10/851 - Thermoelectric active materials comprising inorganic compositions
• C01B 33/06 - Metal silicides
• C04B 35/58 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides

Abstract

Image data corresponding to an ultrasonic image showing a pelvic region of a subject is acquired. A plurality of feature points relating to a prescribed section are extracted by applying image processing to the image data. An index value associated with at least one of lower urinary tract function and pelvic floor function is calculated on the basis of the plurality of feature points.

IPC Classes  ?

• A61B 8/14 - Echo-tomography
• A61B 8/08 - Clinical applications
• G06T 7/00 - Image analysis

Abstract

Provided is a curable composition that is excellent in low dielectric properties. One embodiment of the present invention is a curable composition containing a polysiloxane having an epoxy group and a compound represented by formula (1). In the formula, G represents an organic group, and X represents a group represented by general formula (1) -11, general formula (1) -12, general formula (1) -13, or general formula (1) -14.

IPC Classes  ?

• C08G 59/20 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups characterised by the epoxy compounds used
• C08G 59/40 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups characterised by the curing agents used

Abstract

Provided is a hydrogel comprising a self-assembled peptide and a mesh polymer, wherein the mesh polymer has a hydrophilic polymer block derived from a hydrophilic polymer and a polyethylene glycol block derived from polyethylene glycol; and the hydrophilic polymer block and the polyethylene glycol block are bound through a divalent group containing a hydrazone bond represented by -C=N-NH-.

IPC Classes  ?

• C08L 87/00 - Compositions of unspecified macromolecular compounds, obtained otherwise than by polymerisation reactions only involving unsaturated carbon-to-carbon bonds
• C08G 81/00 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
• C08L 89/00 - Compositions of proteinsCompositions of derivatives thereof
• C07K 2/00 - Peptides of undefined number of amino acidsDerivatives thereof

Abstract

A transmission device for performing information communication with one or more reception devices includes a communication history information storage unit configured to store communication history information in which a communication parameter for performing the information communication is associated with a deterioration rate that is a value based on radio waves transmitted using the communication parameter when information is transmitted to the reception device and radio waves received from the reception device, a calculation unit configured to calculate the communication parameter when communication with the reception device is performed on the basis of the stored communication history information, and an output unit configured to output the calculated communication parameter.

IPC Classes  ?

• H04W 52/02 - Power saving arrangements

Abstract

A flexoelectric liquid crystal composition containing at least one kind of smectic liquid crystal compound, a chiral dopant, and a charge scavenger, and exhibiting photoconductivity.

IPC Classes  ?

• G01N 29/24 - Probes
• C09K 19/02 - Liquid crystal materials characterised by optical, electrical or physical properties of the components, in general
• C09K 19/34 - Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
• C09K 19/54 - Additives having no specific mesophase
• C09K 19/58 - Dopants or charge transfer agents
• G01N 29/04 - Analysing solids

Abstract

Provided are: a chimeric protein which comprises an extracellular domain capable of recognizing and binding to a peptide tag comprising the amino acid sequence represented by SEQ ID NO:1, a transmembrane domain, and an intracellular domain containing a signal domain capable of activating the cytotoxicity of a T cell or an NK cell when the extracellular domain is bound to the peptide tag; and a nucleic acid, a vector, a T cell or an NK cell, a pharmaceutical composition, a combined product, a combined pharmaceutical, and a target antigen binding protein, each associated with the chimeric protein.

IPC Classes  ?

• C07K 19/00 - Hybrid peptides
• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
• A61K 47/66 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 31/12 - Antivirals
• A61P 35/00 - Antineoplastic agents
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• C07K 14/725 - T-cell receptors
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/13 - Immunoglobulins
• C12N 15/62 - DNA sequences coding for fusion proteins
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

This thermally conductive composition comprises a matrix having a cross-linked structure and a filler dispersed inside the matrix. The thermal conductivity of the filler is greater than or equal to the thermal conductivity of the matrix. The matrix is a cellulose derivative in which the hydroxy groups of alkylated cellulose are at least partially substituted with alkanoyl groups and at least one selected from acryloyl groups and methacryloyl groups.

IPC Classes  ?

• C08L 1/08 - Cellulose derivatives
• C08F 290/10 - Polymers provided for in subclass
• C08K 3/013 - Fillers, pigments or reinforcing additives

Abstract

This thermally-conductive composition comprises: a matrix having a crosslinked structure; and a filler dispersed inside the matrix. The thermal conductivity of the filler is greater than or equal to the thermal conductivity of the matrix. The matrix is a cellulose derivative in which at least a part of the hydroxy groups that alkyl cellulose has are substituted with: at least one selected from an acryloyl group and a methacryloyl group; and an alkanoyl group.

IPC Classes  ?

• C08L 1/08 - Cellulose derivatives
• C08K 3/013 - Fillers, pigments or reinforcing additives

Abstract

Provided are: a biofuel cell which exhibits good output characteristics with a low environmental load at a low cost; and an electrode for biofuel cells, an enzyme electrode, and an electrode slurry for biofuel cells, each of which is suitable for use in this biofuel cell. A biofuel cell according to the present invention generates electric power by means of an oxidation-reduction reaction using an enzyme as a catalyst. In this biofuel cell: the enzyme is immobilized on at least one of an anode and a cathode; the anode contains a conductive material (1) and an electrode binder (1); the cathode contains a conductive material (2) and an electrode binder (2); at least one of the electrode binder (1) and the electrode binder (2) contains a polymer (A); the polymer (A) has a first structural unit derived from a nonionic ethylenically unsaturated monomer (a1), a second structural unit derived from an anionic ethylenically unsaturated monomer (a2), and a third structural unit derived from a crosslinking agent (a3); and the crosslinking agent (a3) has two or more ethylenically unsaturated bonds in each molecule.

IPC Classes  ?

• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 8/16 - Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts

Abstract

An analysis device according to the present invention is provided with: a detection unit that detects pulse signals generated by an optical sensor; and an analysis unit that, on the basis of the pulse signals, analyzes a radiation source being considered as a subject of measurement and serving as a radiation generation source. The detection unit detects a first pulse signal generated by the optical sensor that has received excitation light emitted from molecules of a gas generated from radiation when the radiation is emitted from the subject of measurement. Furthermore, each time secondary electrons move to an anode electrode due to an electric field with the flight path of the radiation maintained, whereby a group of secondary electrons following the flight path reach the anode electrode, the detection unit detects a second pulse signal generated by the optical sensor that has received light emitted as a result of avalanche amplification of the group of secondary electrons. The analysis unit estimates the generation position of the radiation source as analysis on the basis of the time difference between the trailing edges of the first pulse signal and the second pulse signal.

IPC Classes  ?

• G01T 1/18 - Measuring radiation intensity with counting-tube arrangements, e.g. with Geiger counters
• G01T 1/20 - Measuring radiation intensity with scintillation detectors

Abstract

A chip holding tool (12) comprises: a holding surface (24) for holding a semiconductor chip (100) in a non-contact manner; a suction path (33) for providing negative pressure at the holding surface (24) and drawing the semiconductor chip (100) by suction; and an ultrasonic generator (14) for providing ultrasonic oscillation to the holding surface (24), wherein the size of the outer shape of the holding surface (24) is larger than the size of the outer shape of the semiconductor chip (100). A positioning groove (36) having a shape conforming to at least a portion of the outer shape of the semiconductor chip (100) is formed in the holding surface (24).

IPC Classes  ?

• H01L 21/677 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components for conveying, e.g. between different work stations
• H01L 21/67 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components

Abstract

A eutectic electrolyte for a secondary battery containing a lithium salt or a sodium salt, and a solid amine compound capable of forming a eutectic solvent with the lithium salt or the sodium salt; and a secondary battery containing the same. (The solid amine compound excludes acetoamide and methyl carbamic acid.)

IPC Classes  ?

• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/052 - Li-accumulators
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes

Abstract

An impedance parameter measurement method according to an embodiment of the present technology is a method for measuring an impedance parameter of an electrochemical device in which an electric circuit including a CPE serves as an equivalent circuit, and includes the following: (A) applying step-like current changes to the electrochemical device; (B) measuring the voltage of the electrochemical device at a plurality of different timings while the voltage of the electrochemical device is exhibiting a transient response to the application of current changes to the electrochemical device; and (C) deriving a p-constant for the CPE on the basis of the plurality of voltage values obtained from the measurement and deriving a T-constant for the CPE on the basis of the derived p-constant and the plurality of voltage values obtained from the measurement.

IPC Classes  ?

• G01R 31/389 - Measuring internal impedance, internal conductance or related variables
• G01R 27/02 - Measuring real or complex resistance, reactance, impedance, or other two-pole characteristics derived therefrom, e.g. time constant
• G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
• G01R 31/392 - Determining battery ageing or deterioration, e.g. state of health
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries

Abstract

Provided is a manufacturing method of a cured body, the method including: a first step for mixing a composition containing a carbonate containing one or more elements selected from calcium and magnesium, or hydrate thereof, with a liquid containing a soluble alkaline earth metal salt, and press molding the mixture to produce a molded body; and a second step for drying the molded body.

IPC Classes  ?

• C04B 28/00 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
• B28B 1/30 - Producing shaped articles from the material by applying the material on to a core, or other moulding surface to form a layer thereon
• B28B 3/00 - Producing shaped articles from the material by using pressesPresses specially adapted therefor
• C04B 7/24 - Cements from oil shales, residues or waste other than slag

Abstract

A glycosylated neuropeptide derivative, having a neuropeptide sequence, a cell-penetration accelerating sequence, an endosomal-escape accelerating sequence, and a sugar chain.

IPC Classes  ?

• C07K 14/605 - Glucagons
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 38/00 - Medicinal preparations containing peptides
• A61P 25/24 - Antidepressants
• C07K 1/107 - General processes for the preparation of peptides by chemical modification of precursor peptides

Abstract

There is provided an item detection device that detects an item to be loaded and unloaded and includes an image acquisition unit acquiring a posture detection unit detecting the posture of the part to be loaded and unloaded on the basis of a computation result of the computing unit. The posture detection unit scans the second information image across a first region in which the feature part is present and a second region in which the feature part is not present to acquire a change in a visual parameter, calculates notation information indicating the boundary portion of the item on the basis of the change in the visual parameter, detects the feature line on the basis of the notation information, and detects the posture on the basis of a difference in angle between the feature line and a reference line in the second information image.

IPC Classes  ?

• G06V 20/56 - Context or environment of the image exterior to a vehicle by using sensors mounted on the vehicle
• G06T 7/73 - Determining position or orientation of objects or cameras using feature-based methods

Abstract

A novel nucleic acid oligomer and a method for producing the same. The nucleic acid oligomer includes a nucleotide unit represented by general formula (1) and a nucleotide unit represented by general formula (2), and optionally includes a nucleotide unit represented by general formula (3). In general formulas (1), (2), and (3): R1 represents a hydrogen atom, a hydroxyl group, an alkoxy group, an alkenyloxy group, an acyloxy group, a trialkylsilyloxy group, an alkoxyalkoxy group, a haloalkoxyalkoxy group, or a halogenyl group, and R2 represents a hydrogen atom, or R1 and R2 bond together to form a five- or more-membered ring optionally having a substituent and optionally having a hetero atom; Bs represents a nucleobase selected from the group consisting of adenine, guanine, cytosine, 5-methylcytosine, thymine, and uracil, the nucleobase optionally having a nucleobase protecting group; and X+ represents a counter cation A novel nucleic acid oligomer and a method for producing the same. The nucleic acid oligomer includes a nucleotide unit represented by general formula (1) and a nucleotide unit represented by general formula (2), and optionally includes a nucleotide unit represented by general formula (3). In general formulas (1), (2), and (3): R1 represents a hydrogen atom, a hydroxyl group, an alkoxy group, an alkenyloxy group, an acyloxy group, a trialkylsilyloxy group, an alkoxyalkoxy group, a haloalkoxyalkoxy group, or a halogenyl group, and R2 represents a hydrogen atom, or R1 and R2 bond together to form a five- or more-membered ring optionally having a substituent and optionally having a hetero atom; Bs represents a nucleobase selected from the group consisting of adenine, guanine, cytosine, 5-methylcytosine, thymine, and uracil, the nucleobase optionally having a nucleobase protecting group; and X+ represents a counter cation

IPC Classes  ?

• C07H 23/00 - Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
• C07H 1/00 - Processes for the preparation of sugar derivatives

Abstract

A transmitter in one aspect of the present invention generates a pulse code string by coding transmission information according to allocation of respective pulse code strings to codewords, and transmits the generated pulse code string. The pulse code strings each include at least four pulses. The pulse code strings are designed such that any pair of the pulse code strings has, at most, two common pulses under all possible shifts of discrete time slots. The foregoing provides a communication technology by which improvement of data rate in data communication among a large number of devices can be expected.

IPC Classes  ?

• H04L 25/49 - Transmitting circuitsReceiving circuits using code conversion at the transmitterTransmitting circuitsReceiving circuits using predistortionTransmitting circuitsReceiving circuits using insertion of idle bits for obtaining a desired frequency spectrumTransmitting circuitsReceiving circuits using three or more amplitude levels
• H03M 7/20 - Conversion to or from n-out-of-m codes
• H04J 13/10 - Code generation

Abstract

An alignment method for a first semiconductor chip (221) and a second semiconductor chip (231) to be stacked, wherein the first semiconductor chip (221) is ultrasonically vibrated, a lower surface (231a) of the second semiconductor chip (231) is brought close to an upper surface (221a) of the first semiconductor chip (221) so as to overlap the first semiconductor chip (221) that is vibrating ultrasonically and the second semiconductor chip (231) is released to self-align the second semiconductor chip (231) on the first semiconductor chip (221).

IPC Classes  ?

• H01L 21/60 - Attaching leads or other conductive members, to be used for carrying current to or from the device in operation
• H01L 21/50 - Assembly of semiconductor devices using processes or apparatus not provided for in a single one of the groups or
• H01L 21/607 - Attaching leads or other conductive members, to be used for carrying current to or from the device in operation involving the application of mechanical vibrations, e.g. ultrasonic vibrations
• H01L 21/67 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components
• H01L 21/68 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components for positioning, orientation or alignment
• H01L 25/065 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
• H01L 25/07 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in subclass
• H01L 25/18 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices the devices being of types provided for in two or more different main groups of the same subclass of , , , , or

Abstract

Provided are a method for producing genome-edited cells that introduces a nucleic acid containing a donor nucleic acid into the genome of cells during the process of meiosis of fused cells and a method for promoting hybridization that crosses two or more types of cells during the process of meiosis of two or more types of cells having different traits that have been fused.

IPC Classes  ?

• C12N 15/09 - Recombinant DNA-technology
• C12N 15/04 - Fungi
• C12N 15/05 - Plant cells
• C12N 15/06 - Animal cells

Abstract

A gold alloy and a method for producing the gold alloy. The gold alloy includes: gold; and an Au—X-RE-based hypermaterial represented by a compositional formula AU100-(a+b)XaREb, wherein, in the compositional formula, X represents at least one atom selected from the group consisting of Al, Ga, In, Si, Ge, and Sn; RE represents a rare-earth element; and a and b respectively represent a content of X and a content of RE, expressed in at %, and satisfy the following (1) and (2): 10≤a≤40 (1); and 13≤b≤17 (2), wherein the Au—X-RE-based hypermaterial is dispersed in a gold matrix phase.

IPC Classes  ?

• C22C 5/02 - Alloys based on gold
• C22C 1/02 - Making non-ferrous alloys by melting

Abstract

It would be helpful to provide a sheet-form thermoelectric conversion module with excellent thermoelectric conversion characteristics. A thermoelectric conversion module according to the disclosure is a thermoelectric conversion module formed in sheet form, the thermoelectric conversion module being disposed in contact or proximity to a heat source and generating power based on a temperature difference between a portion close to the heat source and a portion away from the heat source, the thermoelectric conversion module including an incision penetrating in a sheet thickness direction, wherein by stretching the thermoelectric conversion module in a predetermined direction, mutually opposite edges of the incision are separated, and the thermoelectric conversion module is transformed from a sheet form A into a three-dimensional structural form B protruding in the sheet thickness direction.

IPC Classes  ?

• H10N 10/17 - Thermoelectric devices comprising a junction of dissimilar materials, i.e. devices exhibiting Seebeck or Peltier effects operating with only the Peltier or Seebeck effects characterised by the structure or configuration of the cell or thermocouple forming the device

Abstract

Provided is a transmission device which performs information communication with at least one reception device, said transmission device comprising: a communication history information acquisition unit for acquiring communication history information in which are associated a communication parameter that is for performing the information communication and a degradation ratio that is a value based on radio waves transmitted using the communication parameter when transmitting information to the reception device and radio waves received from the reception device; a calculation unit for calculating, on the basis of the acquired communication history information, the value of the communication parameter including a second parameter and a third parameter such that a first parameter, which is a value obtained as a result of the information communication, is substantially constant; and an output unit for outputting the calculated communication parameter. The second parameter and the third parameter both relate to the information communication.

IPC Classes  ?

• H04W 28/18 - Negotiating wireless communication parameters
• H04W 52/24 - TPC being performed according to specific parameters using SIR [Signal to Interference Ratio] or other wireless path parameters
• H04W 84/10 - Small scale networksFlat hierarchical networks
• H04W 84/20 - Leader-follower arrangements

Abstract

This physiologically-active peptide derivative for the treatment of eye diseases comprises a physiologically-active peptide sequence and a functional sequence comprising a membrane permeation-promoting sequence and an endosomal escape-promoting sequence.

IPC Classes  ?

• C07K 19/00 - Hybrid peptides
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
• A61P 27/02 - Ophthalmic agents
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• A61K 38/26 - Glucagons
• C07K 14/605 - Glucagons

Abstract

The present invention pertains to a vehicle control device and a vehicle control method that generate an assist control input on the basis of a zeroing control barrier function in response to an operation input for changing a traveling state of a vehicle, and control the traveling state on the basis of the operation input and the assist control input. The vehicle control device and the vehicle control method find a subset of a safe set, which represents a predetermined safe area considered safe, on the basis of predetermined constraints related to the operation input and the control input, and determine whether an initial state of the vehicle at the start of control belongs to the found subset or not, and consequently, when it is determined that the initial state belongs to the subset, control the traveling state on the basis of the operation input and the assist control input.

IPC Classes  ?

• B60W 30/095 - Predicting travel path or likelihood of collision

Abstract

The present invention provides a pharmaceutical composition for the treatment or prevention of stress-related disorders, stress-induced anxiety disorders, or stress-related disorders or anxiety disorders associated with depression, the composition containing a selective δ-opioid receptor agonist as an active component, wherein the selective δ-opioid receptor agonist preferably also has a μ-opioid receptor antagonist action and a κ-opioid receptor antagonist action.

IPC Classes  ?

• A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
• A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
• A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
• A61K 31/513 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
• A61P 25/22 - Anxiolytics

Abstract

A glycosylated neuropeptide derivative comprising a neuropeptide sequence, a membrane-penetration-promoting sequence, an endosomal-escape-promoting sequence, and a sugar chain.

IPC Classes  ?

• C07K 19/00 - Hybrid peptides
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
• A61P 25/18 - Antipsychotics, i.e. neurolepticsDrugs for mania or schizophrenia
• A61P 25/24 - Antidepressants
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• C12N 15/12 - Genes encoding animal proteins

Abstract

A compound represented by formula (1) below, useful for treating cancer. In the formula, R1 and R3-R8 each independently represents a hydrogen atom or an alkyl group, R2 represents a hydrogen atom or a group represented by —ORa, R9 represents a group represented by —C(O)NRcRf, Ra, Re, and Rf each independently represents a hydrogen atom, an arylalkyl group that may have a substituent, or a heteroarylalkyl group. A production method that enables the compound to be produced with high efficiency, and a pharmaceutical composition containing the compound as an active ingredient A compound represented by formula (1) below, useful for treating cancer. In the formula, R1 and R3-R8 each independently represents a hydrogen atom or an alkyl group, R2 represents a hydrogen atom or a group represented by —ORa, R9 represents a group represented by —C(O)NRcRf, Ra, Re, and Rf each independently represents a hydrogen atom, an arylalkyl group that may have a substituent, or a heteroarylalkyl group. A production method that enables the compound to be produced with high efficiency, and a pharmaceutical composition containing the compound as an active ingredient

IPC Classes  ?

• C07D 263/32 - Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
• C07D 213/56 - Amides
• C07D 277/30 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

Provided is a production method of cells into which exogenous mitochondria have been introduced, the production method comprising culturing recipient cells using cell culture equipment in which mitochondria isolated from donor cells are coated on the culture surface, and incorporating the mitochondria into the recipient cells. Also provided are cells produced by the production method, the cells having exogenous mitochondria introduced thereinto. Also provided are a cell culture substrate usable in the aforesaid production method and a method for manufacturing the same, and a cell culture kit.

IPC Classes  ?

• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/87 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
• C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells

Abstract

The present invention addresses the problem of providing a three-dimensional tissue culture and a method for producing the same. The problem is solved by this method for producing a three-dimensional tissue culture, the method comprising: a step for seeding first cells on a culture substrate, applying a centrifugal force, and subsequently culturing the cells to form a first cell layer; and a step for seeding second cells on the first cell layer, applying a centrifugal force, and subsequently culturing the cells to laminate a second cell layer.

IPC Classes  ?

• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
• A61L 27/38 - Animal cells

Abstract

An information processing apparatus includes a converting portion having a plurality of electrical conductors to be arranged in mutual separation and a medium arranged so as to mutually connect the plurality of electrical conductors, wherein the converting portion is the information processing apparatus to convert an input signal to an output signal. The medium includes the electrolyte and is configured to be capable of controlling an electrical conductivity of an electrically conductive path mutually electrically connecting the plurality of electrical conductors, and the medium is selected such that the electrical conductivity of the electrically conductive path changes over time with the input signal not being present.

IPC Classes  ?

• H01B 7/00 - Insulated conductors or cables characterised by their form

Abstract

An estrogen derivatization method uses a quaternary cation-containing 5-fluoro-2,4-dinitrophenyl compound represented by Formula (1): An estrogen derivatization method uses a quaternary cation-containing 5-fluoro-2,4-dinitrophenyl compound represented by Formula (1): where in Formula (1), X is a quaternary cation. A mass spectrometry method includes derivatizing estrogen by the above estrogen derivatization method. A derivatization reagent derivatizing estrogen includes a quaternary cation-containing 5-fluoro-2,4-dinitrophenyl compound represented by Formula (1), where in Formula (1), X is a quaternary cation.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

Provided are: a corrosion-resistant stainless steel comprising a stainless steel substrate and a surface layer containing tungsten oxide on at least one surface of the stainless steel substrate; and a method of manufacturing the same.

IPC Classes  ?

• C25D 9/06 - Electrolytic coating other than with metals with inorganic materials by anodic processes
• H01M 8/021 - Alloys based on iron
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

A non-human animal or a part of the same in which the function of Mipep gene is totally or partially lost in adipose tissues or the expression level of Mipep gene in adipose tissues is lowered compared to a wild type; and mesenchymal stem cells or adipocytes in which the function of Mipep gene is totally or partially lost or the expression level of Mipep gene is lowered compared to a wild type. A therapeutic or prophylactic drug that includes the mesenchymal stem cells or adipocytes or a culture supernatant thereof; and a method for preparing a mitokine mixture using the non-human cells, mesenchymal stem cells or adipocytes.

IPC Classes  ?

• A61K 35/28 - Bone marrowHaematopoietic stem cellsMesenchymal stem cells of any origin, e.g. adipose-derived stem cells
• A01K 67/027 - New or modified breeds of vertebrates
• A61K 35/35 - Fat tissueAdipocytesStromal cellsConnective tissues

Abstract

This power conversion device converts power in order to transfer power in both directions between a first apparatus and a second apparatus and comprises: a transformer unit having a core, a plurality of primary-side windings wound around the core, and a secondary-side winding wound around the core; a first circuit for transferring power between each of the plurality of primary-side windings and the first apparatus; and a second circuit for transferring power between the secondary-side winding and the second apparatus. The plurality of primary-side windings are each connected to the first circuit via a separate filter so that the frequency bands of power whereby each of the primary-side windings are made to operate differ from each other between the plurality of primary-side windings, and the first circuit and the second circuit are configured so that the frequency of power whereby the transformer unit is made to operate can be changed in accordance with the primary-side winding used for power conversion in the transformer unit among the plurality of primary-side windings.

IPC Classes  ?

• H02M 3/28 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC

Abstract

Disclosed is a novel treatment method in which the effectiveness of cancer treatment is improved by using an immune checkpoint regulator in combination. An anticancer drug according to the present invention has, as an active ingredient, a compound that is N-(4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-3-yl)-3-(piperidine-1-yl)benzamide, a pharmacologically acceptable salt thereof, or a solvate of said compound or said salt, the anticancer drug being used in combination with at least one immune checkpoint regulator. The immune checkpoint regulator is, e.g., an immune checkpoint inhibitor such as an antagonistic anti-PD-1 antibody.

IPC Classes  ?

• A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61P 35/00 - Antineoplastic agents
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

The present invention addresses the problem of providing: a diastereomer preparation method whereby it becomes possible to produce a desired diastereomer from a diastereomer mixture with high efficiency; and a solid-phase photosensitizer which is used in the diastereomer preparation method. The solution for the problem is a diastereomer preparation method in which one diastereomer among cis-trans isomers is selectively prepared utilizing recycle HPLC, the method comprising: a step A that is a separation step for introducing a cis-trans isomer mixture into the separation column to selectively collect one diastereomer; a step B that is a photoisomerization reaction step for irradiating a solution containing the other diastereomer which is obtained after the step A or C with light in the presence of a photosensitizer in a photoisomerization reactor to induce a photoisomerization reaction; and a step C that is a step for introducing a cis-trans isomer mixture produced in the step B into a separation column to selectively collect the one diastereomer.

IPC Classes  ?

• C07C 231/24 - SeparationPurification
• C07C 231/12 - Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
• C07C 233/11 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
• C07C 235/34 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
• C07C 259/06 - Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
• C07D 335/16 - Oxygen atoms, e.g. thioxanthones
• C09K 3/00 - Materials not provided for elsewhere
• B01D 15/14 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus

Abstract

Provided is a radiation measuring device comprising: a gas scintillator; at least two optical sensors that generate pulse signals in response to the reception of scintillation light; and a detection unit that detects the generation of radiation on the basis of the pulse signals generated by each of the optical sensors, wherein the detection unit excludes a calculation result less than a prescribed threshold, from calculation results for the pulse signals generated by the optical sensors during a prescribed time period in a state in which an object to be measured for the radiation is present in the gas scintillator, and the detection unit thereby detects the radiation generated by the object to be measured, and the threshold value is determined through calculations for the pulse signals generated by the optical sensors during a prescribed time period in a state in which the object to be measured for the radiation is not present in the gas scintillator.

IPC Classes  ?

• G01T 1/20 - Measuring radiation intensity with scintillation detectors
• G01T 1/205 - Measuring radiation intensity with scintillation detectors the detector being a gas
• G01T 1/208 - Circuits specially adapted for scintillation detectors, e.g. for the photo-multiplier section

Abstract

x6y22O, at least a portion of the Prussian blue analog particles has a monoclinic crystal structure, x is a number of 1.5-2, y is a number greater than 0 and less than or equal to 1, and n is a number greater than or equal to 0.

IPC Classes  ?

• G01N 27/333 - Ion-selective electrodes or membranes
• G01N 27/416 - Systems

Abstract

xxFeFe, wherein x represents a number that is more than 0 but not more than 2.

IPC Classes  ?

• G01N 27/333 - Ion-selective electrodes or membranes
• G01N 27/416 - Systems

Abstract

This phenolic compound production method is a method for producing a compound represented by formula (2) from a compound represented by formula (1), and comprises a step for bringing an enzyme into contact with the compound represented by formula (1), wherein the enzyme has an activity of cleaving the carbon-carbon double bond of the compound represented by formula (1) (excluding the case where the compound represented by formula (1) is ferulic acid and the enzyme is a protein having the amino acid sequence represented by SEQ ID NO: 1). In the formula, R1represents a hydrogen atom or an alkyl group, R2 each independently represents an alkoxy group, a hydroxy group, an alkyl group or a halogen atom, and n is a number of 0-4.

IPC Classes  ?

• C12N 15/53 - Oxidoreductases (1)
• C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
• C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
• C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12P 7/22 - Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic

Abstract

[Problem] To provide a carbon nanotube production device and production method capable of producing high-purity carbon nanotubes. [Solution] The first production device 100 comprises mainly a raw material furnace 120, a production furnace 140, a forward valve 160, and a reverse valve 180. The raw material furnace 120 and production furnace 140 are equipped with a quartz tube and a heater. The forward valve 160 comprises mainly a first forward valve 164 and a second forward valve 167. The reverse valve 180 comprises mainly a first reverse valve 184 and a second reverse valve 187.

IPC Classes  ?

• C01B 32/16 - Preparation

Abstract

Novel factors which are involved in the mechanism of the onset of IgA nephropathy are explored, and diagnostic, preventive or therapeutic agents for this disease are provided. A method for measuring autoantibodies related to IgA nephropathy, the method comprising measuring the amount of anti-spectrin β IgA antibodies in a sample derived from a living organism.

IPC Classes  ?

• G01N 33/563 - ImmunoassayBiospecific binding assayMaterials therefor involving antibody fragments
• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups

Abstract

The purpose of the present invention is to provide a method for evaluating the occurrence of lymph node metastasis of endometrial cancer or the lymph node metastasis capability of endometrial cancer with high accuracy. Provided is a method for evaluating the occurrence of lymph node metastasis of endometrial cancer, or the lymph node metastasis capability of endometrial cancer or the prognosis of endometrial cancer, the method comprising measuring a value of a specific parameter, then introducing the value to a model that is constructed by machine learning, and then evaluating the occurrence of lymph node metastasis of endometrial cancer, or the lymph node metastasis capability of endometrial cancer or the prognosis of endometrial cancer, in which the model is constructed by machine learning employing a value of the parameter in each patient in a teacher sample group including endometrial cancer patients with lymph node metastasis and endometrial cancer patients without lymph node metastasis as an explanatory variable and also employing data about the presence or absence of lymph node metastasis in each patient in the group as an objective variable.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

Abstract

This double-balloon endoscope comprises: an elongated part that has an elongated shape and has, at the distal end thereof, a balloon that expands and contracts, the distal end portion of the elongated part being capable of being bent by an operation from the exterior; and a cylindrical part that has a cylindrical shape and has, at the distal end thereof, another balloon that expands and contracts, the distance end portion of the cylindrical part being capable of being bent by an operation from the exterior.

IPC Classes  ?

• A61B 1/01 - Guiding arrangements therefor
• A61B 1/008 - Articulations

Abstract

A coating agent has: a film-forming component containing an organosilicon compound having a radical polymerizable functional group and an alkoxysilyl group; and a film-curing component composed so that a base and a radical can be generated on irradiation with ultraviolet light. The film-curing component includes a nonionic photobase generator having no ionic bond in the molecular structure. The content of the nonionic photobase generator is 0.1 parts by mass or more and 50 parts by mass or less, based on 100 parts by mass of the organosilicon compound.

IPC Classes  ?

• C09D 133/14 - Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
• C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
• C09D 7/63 - Additives non-macromolecular organic
• C09D 183/10 - Block or graft copolymers containing polysiloxane sequences
• C08J 7/04 - Coating

Abstract

This product holding device comprises: a stage (32) on which a product is to be placed; and vibration elements (38) that apply ultrasonic vibrations to the product (100) placed on the stage (32), and causes falling foreign matter (110) to float at a location away from the surface of the product (100). In addition, the product holding device (30) further comprises: a transport mechanism (42) that transports the floating foreign matter (110) to a location that is outside the product (100) in a plan view; and a collection mechanism (50) that collects the transported foreign matter (110).

IPC Classes  ?

• H01L 21/52 - Mounting semiconductor bodies in containers

Abstract

Provided is a novel preventative/therapeutic agent which is linked to the complete curing and treatment of IgA nephropathy.　This IgA nephropathy preventative/therapeutic agent targets tonsillar indigenous bacteria derived from an anti-βII spectrin IgA antibody.

IPC Classes  ?

• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61K 39/09 - Streptococcus
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys

Abstract

Provided is a growing condition evaluation system capable of suitably evaluating a development condition of an animal. This growing condition evaluation system 10 comprises: a laser measurement apparatus 13 for receiving laser light that has been emitted toward and reflected from an animal (cow 51), thereby acquiring point group data D1 indicating the appearance of the animal (cow 51) in three-dimensional coordinates; a reference location detection unit 67 for detecting a reference location Pr in the point group data D1; a normalization unit 69 for adjusting the size of the point group data D1 such that the reference location Pr has a uniform size, and generating normalized data D7; an approximation curve calculation unit 74 for calculating an approximation curve Ac that is suitable for the normalized data D7; and an evaluation value calculation unit 75 for calculating, on the basis of the approximation curve Ac, an evaluation value Ev indicating an evaluation of the animal (cow 51).

IPC Classes  ?

• A01K 29/00 - Other apparatus for animal husbandry

Abstract

The present invention has an objective of providing a measurement method capable of precisely and easily measuring the degree of damage of a building caused by an earthquake. The present invention is a measurement method for damage of a building caused by an earthquake, the method involving obtaining the degree of the damage of the building on the basis of a heat quantity of a structure component of the building.

IPC Classes  ?

• G01N 25/72 - Investigating presence of flaws
• G01M 99/00 - Subject matter not provided for in other groups of this subclass

Abstract

Provided are: a maturation suppressor for dendritic cells, said maturation suppressor inhibiting the binding of TARM1 protein to collagen protein to thereby suppress the maturation of dendritic cells; a maturation suppression method for dendritic cells, said method comprising using the maturation suppressor; a pharmaceutical composition containing the maturation suppressor as an active ingredient; a method for screening a maturation suppressor for dendritic cells; and a method for screening a therapeutic component for a disease mediated by dendritic cells.

IPC Classes  ?

• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
• A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The sensor of a fluid sensor system includes an outer peripheral sensor unit including three or more sensor pairs to surround and sandwich the heating element. The computing device of the system includes a first identification unit identifies a sensor pair in which an output difference between an output value corresponding to a temperature detected by one temperature sensor of the sensor pair and an output value corresponding to a temperature detected by the other temperature sensor of the sensor pair is largest, a second identification unit identifies other sensor pairs adjacent to the identified sensor pair in the circumferential direction, and a flow direction estimation unit estimates the flow direction of the fluid on the basis of the output difference in the sensor pair having the largest output difference and output differences in the other sensor pairs adjacent to the sensor pair in the circumferential direction.

IPC Classes  ?

• G01F 1/684 - Structural arrangementsMounting of elements, e.g. in relation to fluid flow
• G01F 1/688 - Structural arrangementsMounting of elements, e.g. in relation to fluid flow using a particular type of heating, cooling or sensing element

Abstract

The present invention realises a radio wave reflector capable of satisfactorily reflecting radio waves of a prescribed frequency. A radio wave reflector 10 has layered therein, in order from a radio wave 1 incidence surface side thereof, a first dielectric layer 11, a resistance layer 12, a second dielectric layer 13, and a reflection layer 14. When the centre wavelength of radio waves reflected by the radio wave reflector is represented by λ, the thickness d of the second dielectric layer satisfies d = λ / 2.

IPC Classes  ?

• H01Q 15/14 - Reflecting surfacesEquivalent structures
• B32B 7/025 - Electric or magnetic properties
• H05K 9/00 - Screening of apparatus or components against electric or magnetic fields

Abstract

The present invention utilizes an electric characteristic due to an electrochemical reaction corresponding to an environmental factor. An interconnection structure according to an embodiment of the present disclosure electrically connects a first portion and a second portion. The interconnection structure comprises a medium between the first portion and the second portion. The electrical connection between the first portion and the second portion is variable by a conductive path which is generated by an electrochemical reaction in the medium. The electrically conductive path has an electric characteristic that varies in accordance with the environment around the medium.

IPC Classes  ?

• H10B 63/00 - Resistance change memory devices, e.g. resistive RAM [ReRAM] devices
• G06G 7/60 - Analogue computers for specific processes, systems, or devices, e.g. simulators for living beings, e.g. their nervous systems
• G11C 11/54 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using elements simulating biological cells, e.g. neuron
• G11C 13/00 - Digital stores characterised by the use of storage elements not covered by groups , , or
• H10N 70/20 - Multistable switching devices, e.g. memristors

Abstract

This information processing device (100) comprises a normal simulation unit (20A), an abnormal simulation unit (20B), and an integration unit (32). The normal simulation unit (20A) calculates, with respect to origination/accumulation equipment that generates and/or accumulates electric power and that is a subject of inspection as to whether installation has occurred, a normal probability distribution representing the cost involved in running under normal circumstances, which indicates a period defined as being normal. The abnormal simulation unit (20B) calculates, with respect to the origination/accumulation equipment, an abnormal probability distribution representing the cost involved in running under abnormal circumstances, which indicates a period defined as being abnormal. The integration unit (32) synthesizes the normal probability distribution and the abnormal probability distribution. Through said synthesis, the integration unit (32) calculates a synthesized probability distribution in which both the running of the origination/accumulation equipment under normal circumstances and the running of the origination/accumulation equipment under abnormal circumstances are taken into consideration.

IPC Classes  ?

• G06Q 50/06 - Energy or water supply

Abstract

The present invention brings assist function to a differential-type omni-directional movement mechanism. The present invention comprises: a first belt drive mechanism 22A which includes a first drive unit 23A and a first drive belt 27A for transmitting a drive force of the first drive unit 23A to a first input shaft 25A; a second drive mechanism 22B which includes a second drive unit 23B and a second drive belt 27B for transmitting a drive force of the second drive unit 23B to a second input shaft 25B; a first torque measurement unit 28A which measures an external torque from a change in tension in the first drive belt 27A; a second torque measurement unit 28B which measures an external torque from a change in tension in the second drive belt 27B; and a control device which controls the first drive unit on the basis of the external torque measured by the first torque measurement unit 28A, and controls the second drive unit on the basis of the external torque measured by the second torque measurement unit 28B.

IPC Classes  ?

• F16H 37/02 - Combinations of mechanical gearings, not provided for in groups comprising essentially only toothed or friction gearings
• B62B 3/00 - Hand carts having more than one axis carrying transport wheelsSteering devices thereforEquipment therefor
• B62D 7/14 - Steering linkageStub axles or their mountings for individually-pivoted wheels, e.g. on king-pins the pivotal axes being situated in more than one plane transverse to the longitudinal centre line of the vehicle, e.g. all-wheel steering

Abstract

A pharmaceutical composition for treating or preventing at least one disease selected from the group consisting of inflammatory bowel disease and intestinal tumor, said pharmaceutical composition comprising an inhibitor for the binding of a dendritic cell immunoreceptor to a double-stranded asialo N-type sugar chain or a dendritic cell immunoreceptor inhibitor together with a pharmaceutically acceptable carrier.

IPC Classes  ?

• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
• A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
• A61P 35/00 - Antineoplastic agents
• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Abstract

An electronic apparatus according to one aspect of the present technology is provided with a voltage difference deriving unit for deriving, on the basis of a voltage value obtained by means of voltage measurement, a difference between a first voltage value, which is the voltage value before a current is changed in a stepwise manner, and a second voltage value, which is the voltage value after the current has been changed in a stepwise manner. The voltage difference deriving unit derives at least two of the following three differences. ∙ A first difference between the first voltage value and a third voltage value, which is the voltage value after a component of the second voltage value originating from a bulk resistance of a battery has changed ∙ A second difference between the first voltage value and a fourth voltage value, which is the voltage value after a component of the second voltage value originating from a charge transfer resistance of the battery has changed ∙ A third difference between the first voltage value and a fifth voltage value, which is the voltage value after a component of the second voltage value originating from a diffusion resistance of the battery has changed

IPC Classes  ?

• G01R 31/389 - Measuring internal impedance, internal conductance or related variables
• G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
• G01R 31/392 - Determining battery ageing or deterioration, e.g. state of health
• G01R 31/396 - Acquisition or processing of data for testing or for monitoring individual cells or groups of cells within a battery
• H01M 10/44 - Methods for charging or discharging
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries

Abstract

A deterioration determining device according to one aspect of the present technology comprises: a plurality of secondary batteries connected in parallel with one another; a plurality of current measuring units which are allocated on a one-to-one basis to each secondary battery, and which are capable of measuring a current flowing through a current pathway of the allocated secondary battery; and a deterioration determining unit capable of identifying a secondary battery in which deterioration has occurred, among the plurality of secondary batteries, on the basis of a relationship between the signs of the currents measured by each current measuring unit.

IPC Classes  ?

• G01R 31/396 - Acquisition or processing of data for testing or for monitoring individual cells or groups of cells within a battery
• G01R 31/392 - Determining battery ageing or deterioration, e.g. state of health
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries

Abstract

An image processing device acquires an image obtained by irradiating an area of a living body with light having a wavelength of 955 [nm] to 2025 [nm]. The image processing device inputs the acquired image to a learned model or a statistical model generated in advance for detecting, from the image, a tumor present in the area, and determines whether or not a tumor is present at each point in the image.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• G06T 7/00 - Image analysis

Abstract

Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.

IPC Classes  ?

• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61P 35/00 - Antineoplastic agents
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• A61K 38/00 - Medicinal preparations containing peptides

Abstract

One embodiment of the present invention provides a curable composition, including a polyfunctional isocyanate compound, a compound selected from the group consisting of a multivalent alcohol and an epoxy compound, and a base amplifier.

IPC Classes  ?

• C08G 18/16 - Catalysts
• C08G 18/18 - Catalysts containing secondary or tertiary amines or salts thereof
• C08G 18/20 - Heterocyclic aminesSalts thereof
• C08G 18/32 - Polyhydroxy compoundsPolyaminesHydroxy amines
• C08G 18/58 - Epoxy resins
• C08G 18/76 - Polyisocyanates or polyisothiocyanates cyclic aromatic
• C08J 5/18 - Manufacture of films or sheets

Abstract

22 production inhibitor which comprises β-glucan having a dectin-1 inhibition activity; and an IL-22BP production promoter which comprises β-glucan having a dectin-1 inhibition activity.

IPC Classes  ?

• A61K 31/716 - Glucans
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61P 35/00 - Antineoplastic agents
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

An electronic appliance according to an embodiment of the present invention is provided with a measurement unit, a storage unit, a calculation unit, and an analysis unit. Both during and after charging or discharging of a battery pack configured to include a plurality of cells, the measurement unit measures the voltages and currents of the plurality of cells included in the battery pack. The storage unit stores the voltage values and current values obtained through the measurement by the measurement unit. The calculation unit calculates, for each of the cells, two or more circuit constants of an equivalent circuit of that cell by using the voltage values and current values stored in the storage unit. The analysis unit performs multivariate analysis by using distribution information concerning the two or more circuit constants of the plurality of cells or distribution information concerning the two or more circuit constants of a plurality of normally operating batteries.

IPC Classes  ?

• G01R 31/392 - Determining battery ageing or deterioration, e.g. state of health
• G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
• G01R 31/389 - Measuring internal impedance, internal conductance or related variables
• G01R 31/396 - Acquisition or processing of data for testing or for monitoring individual cells or groups of cells within a battery
• H01M 10/44 - Methods for charging or discharging
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries

Abstract

The present invention provides a radiation detection device in which the effective surface area and effective volume are increased but expansion of the substrate surface area is limited. Provided is a radiation detection device 100 comprising: an electrode 120 to which a prescribed voltage is applied; a substrate 110 which detects electrons generated by the interaction of radiation with a prescribed gas; and a resistor 130 which is provided between the electrode 120 and the substrate 110, wherein a concentric electric field is formed between the electrode 120 and the substrate 110 by the resistor 130 and the prescribed voltage applied to the electrode 120.

IPC Classes  ?

• G01T 1/18 - Measuring radiation intensity with counting-tube arrangements, e.g. with Geiger counters
• H01J 47/00 - Tubes for determining the presence, intensity, density or energy of radiation or particles

Abstract

The present invention provides a compound, a salt thereof, a solvate thereof, or a prodrug thereof; and an anti-SARS-CoV-2 drug containing the same. The compound is represented by formula (1) [where: R1, R2, and R31-61-61-6-alkoxy group, or -N(Ra)(Rb) (where Raand Rb1-101-10-alkyl group or a substituted or unsubstituted aryl group, and Raand Rbmay form a substituted or unsubstituted 5- to 7-membered ring in conjunction with an adjacent nitrogen atom); R4is -N(Ra)(Rb)(where Raand Rb1-101-10-alkyl group or a substituted or unsubstituted aryl group, and Raand Rb may form a substituted or unsubstituted 5- to 7-membered ring in conjunction with an adjacent nitrogen atom); X is a hydrogen atom, a fluorine atom, a chlorine atom, a bromine atom, or an iodine atom; and the hydroxyl group in the formula may be substituted with a protecting group].

IPC Classes  ?

• A61P 31/14 - Antivirals for RNA viruses
• C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 239/94 - Nitrogen atoms
• C07D 239/95 - QuinazolinesHydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
• A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

Abstract

A liquid circulation system according to one aspect of the present disclosure recovers ionic liquid supplied to inside of a vacuum vessel and returns the ionic liquid back to the inside of the vacuum vessel, the system including: a storage tank that has an opening communicating with the inside of the vacuum vessel, and that stores ionic liquid extracted from the inside of the vacuum vessel through the opening; a viscous pump provided vertically downward relative to the storage tank; and piping that feeds the ionic liquid inside the storage tank to the inside of the vacuum vessel.

IPC Classes  ?

• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• B01J 3/02 - Feed or outlet devices therefor

Abstract

This electrolytic solution additive for a potassium-ion battery or capacitor is a compound represented by formula (1), formula (1A), or formula (1B). In formula (1), formula (1A), and formula (1B), each R independently represents NR1R2, an alkyl group, a cycloalkyl group, a heterocyclic group, an aryl group, or a heteroaryl group, R1and R2each independently represent a hydrogen atom, an alkyl group, an aryl group, or a heteroaryl group, and R1and R2 may be bonded together to form a ring structure. However, regarding R which is bonded to a sulfur atom, when R is a heterocyclic group, the sulfur atom is bonded to an atom other than a nitrogen atom.

IPC Classes  ?

• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01G 11/60 - Liquid electrolytes characterised by the solvent
• H01G 11/64 - Liquid electrolytes characterised by additives
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/0569 - Liquid materials characterised by the solvents

Abstract

A communications device that comprises: a state storage unit that stores state information that is obtained at a specific moment, from among information that changes in accordance with at least either the position of the device or time; an internal state storage unit that associates, and stores, as internal state information, the state information and information used to calculate communications parameters that are used when performing information communication; a calculation unit that calculates the communications parameters on the basis of the state information stored in the state storage unit and on the basis of the internal state information stored in the internal state storage unit; and an output unit that outputs the calculated communications parameters.

IPC Classes  ?

• H04B 1/04 - Circuits
• H04W 24/04 - Arrangements for maintaining operational condition

Abstract

This communication device comprises: an internal state acquisition unit that acquires, from a first device different from the communication device, internal state information indicating the internal state of the first device; an internal state storage unit that stores the acquired internal state information; a calculation unit that performs a process based on the stored internal state information; and an internal state output unit that outputs, at a prescribed succeeding timing, the internal state information stored in the internal state storage unit to a second device different from the first device.

IPC Classes  ?

• H04W 24/04 - Arrangements for maintaining operational condition
• H04W 28/06 - Optimising, e.g. header compression, information sizing

Abstract

[Problem] To provide a rubber product wherein the existence and location of a leak can be simply and accurately detected. [Solution] A rubber product including a gasochromic material in which the color reversibly changes or the electrical resistance value changes due to a redox reaction. A rubber product (seal product 10) that is a seal material for sealing a gap between two members, and includes a gasochromic material in which the color reversibly changes or the electrical resistance value changes due to a redox reaction, wherein the rubber product is ring-shaped.

IPC Classes  ?

• C08L 21/00 - Compositions of unspecified rubbers
• G01M 3/20 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
• G02F 1/17 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on variable-absorption elements not provided for in groups

Abstract

The present invention provides a binder for positive electrode of lithium ion battery which is excellent in workability at the time of producing a positive electrode, is excellent in charge and discharge characteristics such as cycle characteristics and rate characteristics, and enables to possible to produce a positive electrode having an extended cycle life, as well as the present invention provides a slurry for forming positive electrode mixture layer of lithium ion battery, a positive electrode for lithium ion battery, and a lithium ion battery, using the same. As a binder for binding a positive electrode active material, a conductive aid and a current collector at a positive electrode of a lithium ion battery, by using one containing a polysaccharide introduced with at least one ion exchange group selected from the group consisting of sulfate groups and alkali metal sulfate groups, it is possible to provide a lithium ion battery with excellent charge and discharge characteristics and an extended cycle life.

IPC Classes  ?

• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
• C08B 11/12 - Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals substituted with carboxylic radicals

Abstract

A sign detection device is provided with a plurality of sensors, a data acquisition unit, a calculation unit, and a detection unit. The plurality of sensors are respectively disposed at a plurality of positions of a detection target to measure a physical parameter at each positions. A sign detection device is provided with a plurality of sensors, a data acquisition unit, a calculation unit, and a detection unit. The plurality of sensors are respectively disposed at a plurality of positions of a detection target to measure a physical parameter at each positions. The data acquisition unit is configured to acquire time-series change data of the physical parameters from the plurality of sensors. The calculation unit is configured to calculate dynamic network information representing a time change of a complex network structure including a parameter indicating a correlation between the physical parameters at any two positions of the plurality of positions, on the basis of the time-series change data. The detection unit is configured to detect a sign of sudden change vibration of the detection target, on the basis of the dynamic network information.

IPC Classes  ?

• G01M 15/14 - Testing gas-turbine engines or jet-propulsion engines
• F01D 17/02 - Arrangement of sensing elements

Abstract

123456734566 is an electron donor group.

IPC Classes  ?

• C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
• C09K 3/00 - Materials not provided for elsewhere

Abstract

3 represents a hydrogen atom, an acetyl group, a phenoxyacetyl group, a pivaloyl group, a benzyl group, a 4-methoxybenzyl group, a benzoyl group, a triphenylmethyl group, a 4,4′-dimethoxytrityl (DMTr) group, a 4-methoxytrityl (MMTr) group, a 9-phenylxanthenyl group, a trimethylsilyl group, a cyanomethoxymethyl group, a 2-(cyanoethoxy)ethyl group, or a cyanoethoxymethyl group; and X represents a structure represented by any one of Formula B-1 to Formula B-5 shown in the description.

IPC Classes  ?

• C07H 19/073 - Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
• C07F 5/02 - Boron compounds
• C07F 9/6558 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
• C07F 9/6584 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
• C07H 19/173 - Purine radicals with 2-deoxyribosyl as the saccharide radical
• C07H 21/00 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Abstract

Provided are an opioid receptor antagonist, which contains, as an active ingredient, one atropisomer between a pair of atropisomers of a compound represented by formula (1), said atropisomer having an opioid receptor antagonistic action, or a pharmacologically acceptable salt thereof, and a pharmaceutical composition. In formula (1), R1represents a heteroaryl group, etc. and R2and R3 independently represent an alkyl group, etc.

IPC Classes  ?

• A61K 31/4468 - Non-condensed piperidines, e.g. piperocaine having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl
• A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

A photobase generator, includes a compound including a first skeleton represented by the following formula (a); and a second skeleton including a nitrogen atom bonding to a bonding position of the first skeleton to form an amide group, and a pyridine skeleton in addition to the nitrogen atom, in which the compound generates a base in which a hydrogen atom is bonded with the nitrogen atom of the second skeleton by light irradiation. In formula (a), G is a divalent aromatic group, and * represents the bonding position with the nitrogen atom. A photobase generator, includes a compound including a first skeleton represented by the following formula (a); and a second skeleton including a nitrogen atom bonding to a bonding position of the first skeleton to form an amide group, and a pyridine skeleton in addition to the nitrogen atom, in which the compound generates a base in which a hydrogen atom is bonded with the nitrogen atom of the second skeleton by light irradiation. In formula (a), G is a divalent aromatic group, and * represents the bonding position with the nitrogen atom.

IPC Classes  ?

• G03F 7/004 - Photosensitive materials
• C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
• C08K 5/3432 - Six-membered rings

Abstract

In an encryption authentication system, a service server transmits the third encryption information to a user terminal, in a case where the service server receives a request from the user terminal. The user terminal calculates fourth encryption information and transmits the fourth encryption information to an encryption server. The encryption server and the calculation server cooperate with each other to calculate encryption information as a collation target and transmit the encryption information to the service server. The service server obtains a coincidence degree between the first plaintext information included in the encryption information as the collation target and the second plaintext information, by a collation function using a third encryption key and a second encryption key used to calculate registration encryption information, and transmits an authentication result corresponding to the coincidence degree to the user terminal.

IPC Classes  ?

• H04L 9/08 - Key distribution
• H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system

Abstract

Provided are: a membrane permeation enhancer that contains a surfactant having a steroid backbone, and enhances permeation of a complex of an intended substance and a membrane-permeable substance through a lipid bimolecular membrane; and a membrane permeation enhancement method using the membrane permeation enhancer. The present invention also provides: an intracellular delivery method for delivering an intended substance into a cell by bringing a complex of the intended substance and a membrane-permeable substance into contact with the cell in the presence of a membrane permeation enhancer; and a kit that is for intracellular delivery and that is suitably used in the intracellular delivery method.

IPC Classes  ?

• A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
• C07K 5/09 - Tripeptides the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg
• C07K 5/11 - Tetrapeptides the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg
• C07K 7/04 - Linear peptides containing only normal peptide links
• C12N 15/09 - Recombinant DNA-technology

Abstract

x6y22O, where x is a number greater than 0 but less than or equal to 2, y is a number greater than 0 but less than or equal to 1, and n is a number greater than or equal to 0.

IPC Classes  ?

• G01N 27/333 - Ion-selective electrodes or membranes
• G01N 27/416 - Systems

Abstract

A transmission device for performing information communication with one or more reception devices, the transmission device comprising: a communication history information storage unit for storing communication history information in which a communication parameter for performing the information communication is associated with a degradation ratio that is a value based on radio waves transmitted using the communication parameter when information is transmitted to the reception device, and radio waves received from the reception device; a computation unit for computing, on the basis of the stored communication history information, the communication parameter for when performing communication with the reception device; and an output unit for outputting the computed communication parameter.

IPC Classes  ?

• H04W 52/02 - Power saving arrangements
• H04W 76/20 - Manipulation of established connections
• H04W 84/10 - Small scale networksFlat hierarchical networks

Abstract

A flexoelectric liquid crystal composition that comprises at least one type of smectic liquid crystal compound, a chiral dopant, and a charge scavenger, and exhibits photoconductivity.

IPC Classes  ?

• C09K 19/58 - Dopants or charge transfer agents
• G01B 11/06 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness for measuring thickness
• G01N 29/04 - Analysing solids
• G02F 1/13 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells
• G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors

Abstract

A registration device of an individual identification system that includes the registration device, a verification device, and an identification device and that identifies an individual identification target, the registration device including: a registration unit that outputs verification information enabling verification of an identification key that is unique to the identification target, by using, as inputs, an input signal that depends on at least one of a physical property and an image feature of the identification target, and non-physical information that does not depend on the physical property and that differs for each identification target.

IPC Classes  ?

• H04L 9/08 - Key distribution

Abstract

A flexoelectric liquid crystal composition that comprises at least one type of smectic liquid crystal compound, a chiral dopant, and a charge scavenger, and exhibits photoconductivity.

IPC Classes  ?

• G02F 1/13 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells
• C09K 19/58 - Dopants or charge transfer agents
• G01B 11/06 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness for measuring thickness
• G01N 29/04 - Analysing solids
• G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors

Abstract

Proposed is a phase shift introduction method, a structure, and a circuit device for eliminating or minimizing a risk associated with dissimilar materials, solving in principle a problem of mixing of a signal current and a control current that occurs due to DC connection of a phase shifter to a signal line, and stably and reliably providing a phase shift that is desired to be introduced without being adversely effected by noise generated by an ambient magnetic field, which is generated due to use of an external power supply. A structure according to the present invention includes a phase shifter 101 and a closed-loop circuit 103 that is directly used for computation or storage, and a quantum phase shift is generated in the closed-loop circuit 103 by using a fractional flux quantum captured by the phase shifter 101 that is DC-separated from the closed-loop circuit 103.

IPC Classes  ?

• G01R 33/035 - Measuring direction or magnitude of magnetic fields or magnetic flux using superconductive devices
• G06N 10/00 - Quantum computing, i.e. information processing based on quantum-mechanical phenomena
• H10N 60/12 - Josephson-effect devices

Abstract

This third party device is used in a secure computation system which is for performing secure computation by distributing secret information into k or more shared values, where n is defined as the number of servers for storing the shared values and k is defined as a threshold value for restoring the secret information. Said third party device is provided with: a calculation unit for calculating a conversion random number which is a product of k first random numbers for use in secure computation under a condition of n=k without using the secret information; and a transmission unit that transmits the conversion random number to n calculation devices through secret sharing.

IPC Classes  ?

• G09C 1/00 - Apparatus or methods whereby a given sequence of signs, e.g. an intelligible text, is transformed into an unintelligible sequence of signs by transposing the signs or groups of signs or by replacing them by others according to a predetermined system
• G06F 21/60 - Protecting data

Abstract

A power generator includes an electret including a first charged surface and a second charged surface having opposite polarities, a first electrode partially formed on the first charged surface, a second electrode formed on the second charged surface, a third electrode disposed to face the first charged surface with a space, and at least one of a power storage unit or an output unit. The first charged surface has a current collecting surface that is exposed outward. The first electrode and the second electrode form a first power generating unit and the third electrode and the second electrode form a second power generating unit. The electret is formed by polarizing an electret material that includes an inorganic dielectric having a bandgap energy of 4 eV or more.

IPC Classes  ?

• H02N 1/08 - Influence generators with conductive charge carrier, i.e. capacitor machines
• H01G 7/02 - Electrets, i.e. having a permanently-polarised dielectric
• H02K 35/02 - Generators with reciprocating, oscillating or vibrating coil system, magnet, armature or other part of the magnetic circuit with moving magnets and stationary coil systems
• H02N 1/00 - Electrostatic generators or motors using a solid moving electrostatic charge carrier

Abstract

Provided are a novel nucleic acid oligomer and a method for producing the same.　The nucleic acid oligomer according to the present invention includes a nucleotide unit represented by general formula (1) and a nucleotide unit represented by general formula (2), and may or may not include a nucleotide unit represented by general formula (3). In general formulas (1), (2), and (3): R1represents a hydrogen atom, a hydroxyl group, an alkoxy group, an alkenyloxy group, an acyloxy group, a trialkylsilyloxy group, an alkoxyalkoxy group, a haloalkoxyalkoxy group, or a halogenyl group, and R2represents a hydrogen atom, or R1and R2bond together to form a five- or more-membered ring optionally having a substituent and optionally having a hetero atom; Bs represents a nucleobase selected from the group consisting of adenine, guanine, cytosine, 5-methylcytosine, thymine, and uracil, the nucleobase optionally having a nucleobase protecting group; and X+ represents a counter cation.

IPC Classes  ?

• C07H 23/00 - Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Abstract

A novel anti-tumor agent capable of delivering siRNA or shRNA specifically to pancreatic cancer cells and suppressing tumor growth, invasion, and metastasis of pancreatic cancer is provided. The present invention provides a nucleic acid delivery enhancer for delivering siRNA or shRNA into cells, which consists of a folic acid-cationic oligopeptide complex. The present invention also provides an anti-tumor agent having siRNA or shRNA capable of binding to mRNA or snoRNA expressed in pancreatic cancer cells to inhibit its expression and a folic acid-cationic oligopeptide complex. The siRNA is capable of binding to RNA selected from the group consisting of, for example, SNORA18 snoRNA, NUP85 mRNA, WASF2 mRNA, and SNORA22 snoRNA.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
• A61P 35/00 - Antineoplastic agents

Abstract

A power generator includes a power generating unit and at least one of a power storage unit or an output unit that is electrically connected to the power generating unit. The power generating unit includes an electret having a first charged surface and a second charged surface that are charged with opposite polarities, a first electrode formed on the first charged surface, and a second electrode formed on the second charged surface. The electret is formed by polarizing an electret material that includes an inorganic dielectric having a bandgap energy of 4 eV or more. At least one of the first electrode or the second electrode are partially disposed on the corresponding charged surface such that at least one of the first charged surface or the second charged surface has a portion as a current collecting surface exposed outward.

IPC Classes  ?

• H01G 7/02 - Electrets, i.e. having a permanently-polarised dielectric
• H02N 1/08 - Influence generators with conductive charge carrier, i.e. capacitor machines

Abstract

The present invention provides a complex which can be used for a shape memory member that can be driven by local heating by means of the application of an electric current. A complex according to one embodiment of the present invention comprises: a crosslinked polymer that has an endothermic peak when the crosslinked polymer is subjected to differential scanning calorimetry (DSC); and a metal nanowire. The complex has electroconductivity at such a level that the electrical resistance of the complex can be measured in an electroconductivity test in at least a state where the complex is not deformed and a state where the complex is deformed at a scale of 100% or more by applying a stress to the complex in a specific direction from the outside of the complex, and the detachment of the metal nanowire does not substantially occur in a stability test using a good solvent for the crosslinked polymer and/or the metal nanowire.

IPC Classes  ?

• C08F 290/06 - Polymers provided for in subclass
• C08K 7/06 - Elements
• C08L 101/00 - Compositions of unspecified macromolecular compounds
• C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
• C08F 2/46 - Polymerisation initiated by wave energy or particle radiation
• A61L 31/02 - Inorganic materials
• A61L 31/04 - Macromolecular materials
• C08K 3/08 - Metals
• C08G 63/08 - Lactones or lactides
• A61L 27/04 - Metals or alloys
• A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
• A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
• A61L 27/50 - Materials characterised by their function or physical properties

Abstract

Provided is a glycosylated neuropeptide derivative having a neuropeptide sequence, a membrane-penetration-accelerating sequence, an endosomal-escape-accelerating sequence, and a sugar chain.

IPC Classes  ?

• C07K 14/575 - Hormones
• A61K 9/08 - Solutions
• A61K 38/02 - Peptides of undefined number of amino acidsDerivatives thereof
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 25/18 - Antipsychotics, i.e. neurolepticsDrugs for mania or schizophrenia
• A61P 25/24 - Antidepressants
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 14/605 - Glucagons
• C07K 19/00 - Hybrid peptides
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

A nucleic acid amplification method using a solid-phase carrier according to the present invention comprises: capturing a target nucleic acid comprising mRNA on a solid-phase carrier; carrying out complementary-strand synthesis on the solid phase; carrying out exonuclease treatment to degrade and remove unreacted target- capturing nucleic acid on the solid phase; and then carrying out mRNA degradation and homopolymer addition by TdT reaction in the presence of a chain-terminating nucleotide triphosphate. According to the method of the present invention, cDNA can be stably and highly efficiently amplified even from a small amount of sample even in cases where the ratio of the amount of enzyme to the DNA substrate on the solid phase is excessive, where the reaction time is excessive, and/or where reagents show lot-to-lot variation. Further, the amplification method of the present invention can broaden the range of applications of techniques in which analysis using a specific-binding molecule labeled with an oligonucleic acid such as a DNA-labeled antibody and analysis of transcripts are carried out simultaneously.

IPC Classes  ?

• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12Q 1/6874 - Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation [SBH]

Abstract

A photobase generator includes a compound including: first skeletons represented by the following formula (a); and a second skeleton including nitrogen atoms bonding to bonding positions of the first skeletons to form amide groups, wherein, in a molecule, a number of the first skeletons is two or more, a number of the nitrogen atoms, configuring the amide groups, in the second skeleton is the same as the number of the first skeletons, and at least one of the nitrogen atoms configuring the amide groups is converted into a nitrogen atom configuring a secondary amine or a tertiary amine by light irradiation. In the formula (a), G is a divalent aromatic group, and * represents the bonding position with the nitrogen atom. A photobase generator includes a compound including: first skeletons represented by the following formula (a); and a second skeleton including nitrogen atoms bonding to bonding positions of the first skeletons to form amide groups, wherein, in a molecule, a number of the first skeletons is two or more, a number of the nitrogen atoms, configuring the amide groups, in the second skeleton is the same as the number of the first skeletons, and at least one of the nitrogen atoms configuring the amide groups is converted into a nitrogen atom configuring a secondary amine or a tertiary amine by light irradiation. In the formula (a), G is a divalent aromatic group, and * represents the bonding position with the nitrogen atom.

IPC Classes  ?

• C07D 211/94 - Oxygen atom, e.g. piperidine N-oxide

Abstract

A device which, in a shallow region including the epidermal layer or the dermal layer, can administer a target even in extremely small amounts. This includes a puncture needle which, in a flat puncture unit for puncturing the shallow region, has a groove and a through-hole which constitute a recess that extends through part of or the entire thickness of the puncture unit; and a casing which houses the puncture needle so as to allow the puncture needle to advance. By part or all of a flow agent containing the drug being arranged in the groove and the through-hole, the drug is positioned with respect to the puncture unit. The device is designed such that a flow agent in the amount of 10-1000 nL is dosed in the shallow region per puncture.

IPC Classes  ?

• A61B 5/15 - Devices for taking samples of blood
• A61B 5/151 - Devices for taking samples of blood specially adapted for taking samples of capillary blood, e.g. by lancets

Abstract

A soft magnetic alloy containing 1% by atom or more and 10% by atom or less of one or more elements M1 selected from Ga and Ge, substantially containing no Si, and containing Fe and unavoidable impurities as a balance.

IPC Classes  ?

• C22C 38/00 - Ferrous alloys, e.g. steel alloys
• H01F 1/147 - Alloys characterised by their composition