Toyo University

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C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors 4
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G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor 4
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1.

METHOD FOR INHIBITING DECREASE OR PROMOTING INCREASE OF AT LEAST ONE AMONG BONE DENSITY AND BONE STRENGTH, AND VECTOR POTENTIAL GENERATING DEVICE

      
Application Number JP2025013629
Publication Number 2025/146831
Status In Force
Filing Date 2025-04-03
Publication Date 2025-07-10
Owner
  • SUMIDA CORPORATION (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Moriya Hitoshi
  • Saito Masaki
  • Ohsako Masafumi
  • Minamizono Wataru
  • Yashima Nao
  • Matsunaga Hiroya
  • Suito Hirai
  • Fujikawa Kaoru

Abstract

[Problem] To provide a method for inhibiting the decrease or promoting the increase of at least one among bone density (bone mass) and bone strength. [Solution] A method for inhibiting the decrease or promoting the increase of at least one among bone density and bone strength in the tissue of a living body, the method including a step for applying electrical stimulation to the tissue using a vector potential generating device 1, wherein controlling the electrical stimulation by adjusting the alternating current frequency applied to the vector potential generating device 1 inhibits the decrease or promotes the increase of at least one among bone density and bone strength.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

2.

METHOD AND SYSTEM FOR ANONYMIZING IMAGE

      
Application Number JP2024004576
Publication Number 2025/094424
Status In Force
Filing Date 2024-02-09
Publication Date 2025-05-08
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Nosato Hirokazu
  • Iwai Katsuto
  • Nakajima Yuu

Abstract

Provided are an image anonymization method and system capable of achieving high image analysis performance, such as classification, while anonymizing an image. An anonymization model 2 and an analysis model 3 are connected to simultaneously train the anonymization model 2 and the analysis model 3. In the simultaneous training, an analysis error of the analysis model 3 is obtained using a loss function, and the analysis error is propagated back to the analysis model and the anonymization model to correct the weight of the analysis model and correct the weight of the anonymization model. The anonymized image is output from the anonymization model by using the simultaneously trained anonymization model and analysis model.

IPC Classes  ?

3.

IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD, AND PROGRAM

      
Application Number JP2024020474
Publication Number 2025/004719
Status In Force
Filing Date 2024-06-05
Publication Date 2025-01-02
Owner
  • HONDA MOTOR CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor Koshizen Takamasa

Abstract

Provided is an image processing device comprising: a detection unit that detects another vehicle present in an image captured by an image sensor mounted to an own vehicle; and a correction unit that corrects a vanishing point of the image. The correction unit corrects the vanishing point on the basis of a comparison result between a first width of the detected other vehicle and a second width of the other vehicle estimated using the vanishing point.

IPC Classes  ?

4.

DEINOCOCCUS GRANDIS HOST VECTOR SYSTEM

      
Application Number JP2023034784
Publication Number 2024/247295
Status In Force
Filing Date 2023-09-25
Publication Date 2024-12-05
Owner TOYO UNIVERSITY (Japan)
Inventor Narumi Issay

Abstract

[Problem] To provide a Deinococcus grandis host vector system capable of stably introducing and maintaining an expression plasmid in Deinococcus grandis. [Solution] The present invention provides a host vector system comprising: a Deinococcus grandis host cell modified by removing mainly endogenous plasmid pDEGR-3 of Deinococcus grandis or endogenous plasmid pDEGR-3 and endogenous plasmid of 91 or 291 bp; a shuttle vector plasmid comprising a replication initiation region of the endogenous plasmid pDEGR-3 of Deinococcus grandis; and a shuttle vector plasmid comprising a replication initiation region of a plasmid derived from a Deinococcus radiodurans Sark strain.

IPC Classes  ?

  • C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
  • C12N 15/70 - Vectors or expression systems specially adapted for E. coli
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

5.

PREDICTION MODEL AND RISK DETERMINATION METHOD FOR MALE INFERTILITY

      
Application Number JP2024008821
Publication Number 2024/214446
Status In Force
Filing Date 2024-03-07
Publication Date 2024-10-17
Owner TOHO UNIVERSITY (Japan)
Inventor Kobayashi Hideyuki

Abstract

According to the present invention, a risk of male infertility is determined from the concentration of a hormone in a body fluid. A prediction model according to the present invention is for determining a risk of male infertility, the prediction model being a trained model created by performing machine learning using teacher data, which is a set of a feature amount including the concentration of follicle-stimulating hormone in a body fluid of a subject with state information indicating the state of the total number of motile sperms of the subject. This prediction model is characterized by causing a computer to function so as to calculate state information indicating the state of the total number of motile sperms of the subject, when a feature amount including the concentration of follicle-stimulating hormone in the body fluid of the subject is input.

IPC Classes  ?

  • G01N 33/74 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving hormones

6.

METHOD FOR CONTROLLING NUMBER OF ADIPOCYTES

      
Application Number JP2024006001
Publication Number 2024/214393
Status In Force
Filing Date 2024-02-20
Publication Date 2024-10-17
Owner
  • SUMIDA CORPORATION (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Saito Masaki
  • Ohsako Masafumi
  • Suito Hirai

Abstract

[Problem] To control the number of adipocytes in a tissue of a living body. [Solution] Provided is a method including a step for applying electrical stimulation to a tissue of a living body by using a vector potential generator. According to this method for controlling the number of adipocytes, the number of adipocytes can be increased or decreased by the electrical stimulation in which the frequency of alternating current applied to the vector potential generator is controlled.

IPC Classes  ?

  • A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents

7.

METHOD FOR DETECTING CANCER, METHOD FOR PREDICTING PROGNOSIS OF CANCER, BIOMARKER AND METHOD FOR USING SAME, AND KIT FOR DETECTING CANCER OR PREDICTING PROGNOSIS OF CANCER

      
Application Number JP2024011516
Publication Number 2024/203968
Status In Force
Filing Date 2024-03-22
Publication Date 2024-10-03
Owner TOHO UNIVERSITY (Japan)
Inventor Sumazaki, Makoto

Abstract

A method for detecting cancer or predicting prognosis of cancer includes a step for detecting tetraspanin 10 in a sample derived from a body fluid of a subject.

IPC Classes  ?

  • G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof
  • C12Q 1/6813 - Hybridisation assays
  • C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

8.

ARTERIOVENOUS PRESSURE MEASUREMENT DEVICE

      
Application Number JP2024006018
Publication Number 2024/177061
Status In Force
Filing Date 2024-02-20
Publication Date 2024-08-29
Owner
  • LAVIEW CORPORATION (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Masuda Hiroshi
  • Matsumoto Shingo

Abstract

This arteriovenous pressure measurement device (10) comprises a pressure detection unit (34), a capacity detection unit (42), and a calculation unit (441). The pressure detection unit (34) detects the internal pressure of a compression band (20). The capacity detection unit (42) detects the capacity of a fluid present inside the compression band (20). The calculation unit (441) calculates the blood pressure of a subject on the basis of: the internal pressure of the compression band (20) detected by the pressure detection unit (34) when fluid is discharged from the inside of the compression band (20); and the fluid capacity of the compression band (20) detected by the capacity detection unit (42).

IPC Classes  ?

  • A61B 5/022 - Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skinOphthaldynamometers
  • A61B 5/02 - Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow

9.

LASER RESONATOR, OPTICAL COMB GENERATION DEVICE, AND OPTICAL COMB GENERATION METHOD

      
Application Number JP2023045936
Publication Number 2024/166554
Status In Force
Filing Date 2023-12-21
Publication Date 2024-08-15
Owner TOHO UNIVERSITY (Japan)
Inventor Nakajima, Yoshiaki

Abstract

A laser resonator comprising: an excitation light source that outputs excitation light; a gain fiber that absorbs the excitation light and amplifies laser light; and an optical fiber loop which includes an optical fiber with an average core diameter of less than or equal to 8.0 μm.

IPC Classes  ?

  • H01S 3/067 - Fibre lasers
  • G02F 1/383 - Non-linear optics for second-harmonic generation in an optical waveguide structure of the optical fibre type
  • H01S 3/083 - Ring lasers
  • H01S 3/10 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
  • H01S 3/1118 - Semiconductor saturable absorbers, e.g. semiconductor saturable absorber mirrors [SESAMs]Solid-state saturable absorbers, e.g. carbon nanotube [CNT] based

10.

METHOD FOR MANUFACTURING METAL CATALYST-SUPPORTED CARBON MATERIAL

      
Application Number JP2024001736
Publication Number 2024/157949
Status In Force
Filing Date 2024-01-23
Publication Date 2024-08-02
Owner TOYO UNIVERSITY (Japan)
Inventor Gamo Mika

Abstract

Provided is a metal catalyst-supported carbon material having a unique supported form. Provided is a method for supporting a metal catalyst on the surface of a carbon fiber, the method comprising: (a) a step for immersing the carbon fiber in a ketone solvent solution or ether solvent solution containing a compound that contains platinum group catalyst metal ions; and (b) a step for heat-treating, at 200-600 °C, the carbon fiber extracted from the ketone solvent solution or ether solvent solution in the step (a).

IPC Classes  ?

  • B01J 23/89 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with noble metals
  • B01J 35/45 - Nanoparticles
  • B01J 35/58 - Fabrics or filaments
  • B01J 37/02 - Impregnation, coating or precipitation
  • B01J 37/08 - Heat treatment
  • H01M 4/88 - Processes of manufacture
  • H01M 4/92 - Metals of platinum group
  • H01M 4/96 - Carbon-based electrodes
  • H01M 8/10 - Fuel cells with solid electrolytes

11.

CARDIAC ASSIST DEVICE, AND OPERATION METHOD OF CARDIAC ASSIST DEVICE

      
Application Number JP2023045913
Publication Number 2024/154532
Status In Force
Filing Date 2023-12-21
Publication Date 2024-07-25
Owner TOHO UNIVERSITY (Japan)
Inventor Takeda, Yoshimasa

Abstract

A cardiac assist device having: a support means for supporting at least a part of a body; an information acquiring means for acquiring information on the beating of the heart in the body; and a moving means for moving the support means in the direction opposite to the direction of movement of the heart during systole, while synchronizing with the beating on the basis of the acquired information on the beating.

IPC Classes  ?

  • A61M 60/30 - Medical purposes thereof other than the enhancement of the cardiac output
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61G 7/07 - Rests specially adapted therefor for the head or torso
  • A61G 7/018 - Control or drive mechanisms
  • A61M 60/515 - Regulation using real-time patient data

12.

METHOD FOR ASSAYING FIBROBLAST GROWTH FACTOR 18 AND ASSAY REAGENT

      
Application Number JP2023030654
Publication Number 2024/084807
Status In Force
Filing Date 2023-08-25
Publication Date 2024-04-25
Owner TOHO UNIVERSITY (Japan)
Inventor
  • Nakano Hiroyasu
  • Tsuchiya Yuichi
  • Tanaka Masato

Abstract

Provided is a method for assaying fibroblast growth factor 18 (FGF18), whereby FGF18 can be detected/assayed with specificity. In the present invention, fibroblast growth factor 18 (FGF18) in a sample is assayed using a first antibody that binds specifically to the C-terminus region of FGF18.

IPC Classes  ?

  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • C07K 16/22 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors
  • C12N 15/13 - Immunoglobulins
  • G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

13.

GRIPPING TOOL

      
Application Number JP2023007001
Publication Number 2023/163161
Status In Force
Filing Date 2023-02-27
Publication Date 2023-08-31
Owner
  • NATIONAL INDUSTRY INFORMATION RESEARCH INSTITUTE CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
  • TAMAGAWA UNIVERSITY AND TAMAGAWA ACADEMY (Japan)
Inventor
  • Motomura Noboru
  • Sanbayashi Yousuke
  • Nakaya Mitsuhiro
  • Yuba Hirokazu

Abstract

This gripping tool (100) is for gripping an object, the gripping tool (100) comprising: a gripping tool body (10) having a casing (11) and a protective pipe (22) that extends in a first direction (X); a gripping part (20) that is connected to the tip of the protective pipe (22) and that has a clamping arm member (21) for clamping the object; and a clamping operation part (30) that is fixed to the gripping tool body (10) so as to be capable of rotating about a second direction (Y), the clamping operation part performing a clamping operation on the gripping part (20). The gripping tool body (10) is provided with a slider (51) that moves with the operation of the clamping operation part (30), a spring (52) that extends/contracts with the movement of the slider (51), and a gripping drive mechanism (53) for transmitting a gripping operation to the gripping part (20) with the movement of the slider (51).

IPC Classes  ?

  • A61B 17/29 - Forceps for use in minimally invasive surgery

14.

IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD, AND PROGRAM

      
Application Number JP2023002743
Publication Number 2023/145906
Status In Force
Filing Date 2023-01-27
Publication Date 2023-08-03
Owner
  • HONDA MOTOR CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Koshizen Takamasa
  • Sato Fumiaki

Abstract

This image processing device comprises: an object detection unit that detects an object in an image captured from an approximately horizontal direction by an image sensor; a distance estimation unit that, if the detected object is a vehicle, estimates the distance between the vehicle and the image sensor; a virtual line drawing unit that draws a virtual line extending in the lateral direction of the image at a position having a height which is the same as the upper edge of the vehicle in the image; a segmentation execution unit that, if the estimated distance is less than a threshold value, executes segmentation processing for extracting, from the image, a road region on which the vehicle is travelling; and a vanishing point determination unit that determines the height position of a vanishing point of the image on the basis of the virtual line if the estimated distance is at least the threshold value, and determines the height position of the vanishing point on the basis of the extracted road region if the estimated distance is less than the threshold value.

IPC Classes  ?

  • H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
  • G06T 7/00 - Image analysis
  • G06T 7/60 - Analysis of geometric attributes
  • G08G 1/16 - Anti-collision systems

15.

METHOD FOR DETECTING BACTERIA AND KIT FOR DETECTING BACTERIA

      
Application Number JP2022046584
Publication Number 2023/120453
Status In Force
Filing Date 2022-12-19
Publication Date 2023-06-29
Owner
  • NATIONAL UNIVERSITY CORPORATION OITA UNIVERSITY (Japan)
  • NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (Japan)
  • TOHO UNIVERSITY (Japan)
  • NIHON TECHNO SERVICE CO., LTD. (Japan)
Inventor
  • Nakano, Satoko
  • Shimizu, Norio
  • Takase, Hiroshi
  • Mochizuki, Manabu
  • Suzuki, Takashi
  • Tomaru, Yasuhiro

Abstract

According to the present invention, nucleic acids of bacteria are efficiently extracted and detected by PCR. A method for detecting bacteria comprises: a decomposition step for performing the reaction of a proteolytic enzyme in a sample mixture solution of a biological sample and a PCR buffer solution containing a proteolytic enzyme; a deactivation step for deactivating the proteolytic enzyme; and a detection step for adding at least a part of the sample mixture solution after the deactivation step to a PCR reaction composition to amplify a PCR product and detecting the PCR product.

IPC Classes  ?

  • C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/37 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving peptidase or proteinase
  • C12Q 1/686 - Polymerase chain reaction [PCR]
  • C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

16.

METHOD FOR SEPARATING POLYIMIDE FILM

      
Application Number JP2022038918
Publication Number 2023/068294
Status In Force
Filing Date 2022-10-19
Publication Date 2023-04-27
Owner
  • TOHO UNIVERSITY (Japan)
  • NISSAN CHEMICAL CORPORATION (Japan)
Inventor
  • Hasegawa Masatoshi
  • Ishii Junichi
  • Ebara Kazuya

Abstract

A method for separating a polyimide film according to the present invention comprises: a step for forming a titanium oxide film on a glass supporting substrate; a step for forming a polyimide layer on the titanium oxide film; a step for irradiating the glass supporting substrate with ultraviolet light from the back surface side, the back surface being not provided with the polyimide layer, with use of a surface light source; and a step for separating the polyimide layer from the glass supporting substrate, which has the titanium oxide film. (Meanwhile, in cases where both the skeleton of a tetravalent group derived from a tetracarboxylic acid dianhydride and the skeleton of a divalent group derived from diamine in a polyimide do not contain a bond group, and the polyimide is composed only of benzene rings, the polyimide inevitably has a fluorinated alkyl group.) This method for separating a polyimide film enables easy interfacial debonding between a glass supporting substrate and a polyimide layer without using an expensive laser lift-off apparatus or a wet method such as an immersion method and an etching method.

IPC Classes  ?

  • B29C 41/12 - Spreading-out the material on a substrate
  • B29C 41/34 - Component parts, details or accessoriesAuxiliary operations
  • B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
  • B32B 17/06 - Layered products essentially comprising sheet glass, or fibres of glass, slag or the like comprising glass as the main or only constituent of a layer, next to another layer of a specific substance
  • B32B 27/34 - Layered products essentially comprising synthetic resin comprising polyamides
  • C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors
  • C08J 5/18 - Manufacture of films or sheets
  • H05K 3/00 - Apparatus or processes for manufacturing printed circuits

17.

ELECTRODE MATERIAL FOR FUEL CELLS, MEMBRANE ELECTRODE ASSEMBLY FOR FUEL CELLS, AND FUEL CELL

      
Application Number JP2022027102
Publication Number 2023/008147
Status In Force
Filing Date 2022-07-08
Publication Date 2023-02-02
Owner TOYO UNIVERSITY (Japan)
Inventor Gamo Mika

Abstract

The present invention relates to a novel electrode material for fuel fells. More specifically, the present invention relates to an electrode material for fuel fells, the electrode material being composed of carbon fibers, while being characterized in that the carbon fibers being covered with fibrous nanocarbon that supports a catalyst metal.

IPC Classes  ?

  • H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
  • B01J 23/755 - Nickel
  • B01J 23/89 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with noble metals
  • C01B 32/15 - Nanosized carbon materials
  • H01M 8/10 - Fuel cells with solid electrolytes

18.

METHOD FOR AMPLIFYING TARGET GENE HAVING SPECIFIC GC CONTENT

      
Application Number JP2022013805
Publication Number 2022/202954
Status In Force
Filing Date 2022-03-24
Publication Date 2022-09-29
Owner
  • DENKA COMPANY LIMITED (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Tateda, Kazuhiro
  • Miyatake, Yuya

Abstract

The present invention provides a method for amplifying at least one target gene having a GC content of 60% or greater in a reaction solution, wherein: the method includes a step for amplifying a base sequence specific to a target gene using a primer set composed of a first primer and a second primer for amplifying the target gene; one of the primers in the primer set is added to the reaction solution in a higher molar ratio than the other primer; and neither of the primers is a hot-start primer that includes an inactivating chemical modification restored by the action of an activating enzyme.

IPC Classes  ?

  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof
  • C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

19.

METHOD AND KIT FOR IDENTIFYING BACTERIA THAT CAUSE SEPSIS

      
Application Number JP2022014051
Publication Number 2022/203008
Status In Force
Filing Date 2022-03-24
Publication Date 2022-09-29
Owner
  • DENKA COMPANY LIMITED (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Tateda Kazuhiro
  • Miyatake Yuya
  • Sakai Kentarou
  • Higuchi Mizuho
  • Yamauchi Kazuaki

Abstract

Disclosed is a method for identifying bacteria that cause sepsis, wherein the method includes: a step for performing PCR using a sample collected from a subject and a combination of sets of primers each specific to the full length or a partial region of the gyrB gene of Escherichia coli, the nuc gene of Staphylococcus aureus, the atlE gene of Staphylococcus epidermidis, the gyrB gene of Klebsiella pneumoniae, and the rpoB gene of Enterococcus spp.; and a step for detecting any amplification of the full length or the partial region of each of these genes using a combination of probes each specific to the DNA of the full length or the partial region.

IPC Classes  ?

  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof
  • C12Q 1/686 - Polymerase chain reaction [PCR]
  • C12R 1/19 - Escherichia coli
  • C12R 1/22 - Klebsiella
  • C12R 1/445 - Staphylococcus aureus
  • C12R 1/45 - Staphylococcus epidermidis

20.

METHOD FOR GENERATING EMOTIONAL EXPRESSION PHRASE DICTIONARY, METHOD FOR ANALYZING EMOTION IN SENTENCES, EMOTIONAL EXPRESSION PHRASE DICTIONARY, PROGRAM, AND SYSTEM

      
Application Number JP2022005972
Publication Number 2022/181399
Status In Force
Filing Date 2022-02-15
Publication Date 2022-09-01
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Adachi Yoshihiro
  • Kondo Tomohiro
  • Kobayashi Takamitsu
  • Etani Nao
  • Ishii Kaito

Abstract

Provided is a method for generating an emotional expression phrase dictionary D2 that uses a two-dimensional table in key-value format, wherein an emotional expression phrase dictionary generation system 10 acquires a plurality of emotion words and an emotion category vector that expresses the emotion associated with each emotion word, and outputs a two-dimensional table in which the emotion that corresponds to each emotion word is represented as a key (index word) and the emotion category vector associated with the emotion word is represented as a value. The emotional expression phrase dictionary generation system 10 may acquire an expression in base form, with regard to each emotion word, by converting a word included in the emotion word into the base form. A very fast emotion analysis system can be realized by a hash search of the key (index word).

IPC Classes  ?

21.

AUTOFLUORESCENCE QUENCHING DEVICE

      
Application Number JP2022001941
Publication Number 2022/158516
Status In Force
Filing Date 2022-01-20
Publication Date 2022-07-28
Owner
  • TOHO UNIVERSITY (Japan)
  • NEPA GENE CO., LTD. (Japan)
Inventor
  • Tsuneoka, Yousuke
  • Funato, Hiromasa

Abstract

Disclosed is an autofluorescence quenching device that: quenches only autofluorescence without quenching fluorescence that is originally desired to be observed in a tissue section for a short time; does not emit noise in various wavelength regions; is capable of controlling a temperature increase; can be used repeatedly with a simple operation; and can stably quenches autofluorescence. An autofluorescence quenching device for a sample comprises: a sample placement unit; and an irradiation unit that is placed atop the sample placement unit. The sample placement unit is equipped with: a flat plate; one or more sample placement recesses which are provided in the flat plate and in which samples are placed; and a cooling means that cools the sample placement recesses. The irradiation unit is equipped with one or more white LED light-sources that are each placed above the respective sample placement recesses.

IPC Classes  ?

22.

METHOD FOR PREDICTING THERAPEUTIC EFFECT ON PSORIASIS, METHOD FOR EVALUATING CANDIDATE SUBSTANCE FOR TREATING PSORIASIS, AND METHOD AND KIT FOR EVALUATING DISEASE STATE OF PSORIASIS

      
Application Number JP2021019347
Publication Number 2021/246199
Status In Force
Filing Date 2021-05-21
Publication Date 2021-12-09
Owner TOHO UNIVERSITY (Japan)
Inventor
  • Matsunaga, Yukiko
  • Hashimoto, Yuki
  • Ishiko, Akira

Abstract

A method for predicting therapeutic effect on psoriasis, said method comprising predicting the therapeutic effect of a therapy on psoriasis using, as an index, the amount of S100A8/A9 complex in corneocytes of a subject having received the therapy.

IPC Classes  ?

  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • A61P 17/06 - Antipsoriatics
  • C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
  • C12Q 1/06 - Quantitative determination

23.

FAT CELL HYPER-EXPRESSING FFAR4 AND USE THEREOF

      
Application Number JP2021020097
Publication Number 2021/241659
Status In Force
Filing Date 2021-05-26
Publication Date 2021-12-02
Owner
  • NUMT INC. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Takei Yoshinori
  • Hirasawa Akira

Abstract

The present invention provides a new method for treating and/or preventing various ailments such as decreases in cognitive capacity and decreases in glucose tolerance due to aging. The present invention pertains to: fat cells hyper-expressing FFAR4 for treating and/or preventing various ailments, particularly decreases in cognitive capacity that accompany aging and decreases in glucose tolerance that accompany aging; a transplantation composition containing said cells; and a method that uses said transplantation composition to treat and/or prevent various types of ailments. The present invention also pertains to a transgenic mouse hyper-expressing FFAR4.

IPC Classes  ?

  • C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
  • A01K 67/027 - New or modified breeds of vertebrates
  • A61K 35/28 - Bone marrowHaematopoietic stem cellsMesenchymal stem cells of any origin, e.g. adipose-derived stem cells
  • A61K 35/35 - Fat tissueAdipocytesStromal cellsConnective tissues
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 15/86 - Viral vectors

24.

PRIMER SET AND PROBE FOR DETECTING KLEBSIELLA BACTERIA

      
Application Number JP2021013800
Publication Number 2021/201091
Status In Force
Filing Date 2021-03-31
Publication Date 2021-10-07
Owner
  • DENKA COMPANY LIMITED (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Tateda, Kazuhiro
  • Miyatake, Yuya
  • Yamauchi, Kazuaki

Abstract

The present invention provides a primer set for detecting the presence of Klebsiella variicola in a specimen, the primer set comprising a first primer and a second primer that target the gyrB gene of Klebsiella variicola.

IPC Classes  ?

  • C12N 15/31 - Genes encoding microbial proteins, e.g. enterotoxins
  • C12Q 1/6813 - Hybridisation assays
  • C12Q 1/6837 - Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
  • C12Q 1/686 - Polymerase chain reaction [PCR]
  • C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

25.

PRIMER SET AND PROBE FOR DETECTING STAPHYLOCOCCUS ARGENTEUS

      
Application Number JP2021013773
Publication Number 2021/201072
Status In Force
Filing Date 2021-03-31
Publication Date 2021-10-07
Owner
  • DENKA COMPANY LIMITED (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Tateda, Kazuhiro
  • Miyatake, Yuya

Abstract

The present invention provides a primer set for detecting the presence of Staphylococcus argenteus in a specimen, the primer set comprising a first primer and a second primer that target the nuc gene of Staphylococcus argenteus.

IPC Classes  ?

  • C12N 15/55 - Hydrolases (3)
  • C12Q 1/6837 - Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
  • C12Q 1/686 - Polymerase chain reaction [PCR]
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

26.

SPACE SANITIZING AND CLEANING DEVICE

      
Application Number JP2020038411
Publication Number 2021/066203
Status In Force
Filing Date 2020-09-30
Publication Date 2021-04-08
Owner
  • TOHO UNIVERSITY (Japan)
  • SIRIUS CO., LTD. (Japan)
Inventor
  • Iseki, Masahiro
  • Kamei, Ryuhei
  • Tomioka, Yasumitsu

Abstract

The purpose of the present invention is to provide a space sanitizing and cleaning device which uses hypochlorous acid water to sanitize and clean a space, the space sanitizing and cleaning device being capable of using a simple filter configuration to reliably sanitize external air taken in from the surroundings. This space sanitizing and cleaning device is characterized by comprising: an air supply passage 22 that connects together an intake opening 18 and an exhaust opening 20 which are formed in a housing 12; a water storage tank 56 that is disposed within the housing 12; an electrolysis means 60 that electrolyzes salt-containing water stored in the water storage tank 56 to generate hypochlorous acid and electrolyzed hypochlorous acid water in which hypochlorous acid is dissolved; a sanitizing filter 76 that is disposed in the air supply passage 22 in a manner enabling air to pass therethrough; a sanitizing means 48 that causes the electrolyzed hypochlorous acid water generated by the electrolysis means 60 and hypochlorous acid volatilized from the electrolyzed hypochlorous acid water to become included in the sanitizing filter 76; a dust removal HEPA filter 32 that is disposed in the air supply passage 22 in a manner enabling air to pass therethrough, further toward the intake opening 18 side in comparison to the sanitizing filter 76; and a blowing means 28 that generates, in the air supply passage 22, an airstream which is introduced from the intake opening 18, passes successively through the HEPA filter 32 and the sanitizing filter 76, and is discharged from the exhaust opening 20, wherein external air taken in from the intake opening 18 is sanitized, while passing through the sanitizing filter 76, by means of the electrolyzed hypochlorous acid water with which the air is brought into contact through gas-liquid contact in the sanitizing filter 76 and the hypochlorous acid volatilized from the electrolyzed hypochlorous acid water, and the sanitized air is discharged out of the housing 12 from the exhaust opening 20 in a state containing the volatilized hypochlorous acid, whereby the volatilized hypochlorous acid in the discharged air sanitizes the space around the housing 12.

IPC Classes  ?

  • F24F 7/003 - Ventilation in combination with air cleaning
  • A61L 9/01 - Deodorant compositions
  • A61L 9/014 - Deodorant compositions containing sorbent material, e.g. activated carbon
  • A61L 9/12 - Apparatus, e.g. holders, therefor
  • A61L 9/16 - Disinfection, sterilisation or deodorisation of air using physical phenomena
  • C02F 1/461 - Treatment of water, waste water, or sewage by electrochemical methods by electrolysis

27.

SPACE SANITIZING AND CLEANING DEVICE

      
Application Number JP2020038410
Publication Number 2021/066202
Status In Force
Filing Date 2020-09-30
Publication Date 2021-04-08
Owner
  • TOHO UNIVERSITY (Japan)
  • SIRIUS CO., LTD. (Japan)
Inventor
  • Iseki, Masahiro
  • Kamei, Ryuhei
  • Tomioka, Yasumitsu

Abstract

The purpose of the present invention is to provide a space sanitizing and cleaning device which uses hypochlorous acid water to sanitize and clean a space, the space sanitizing and cleaning device being capable of lengthening the lifespan of an electrode and maintaining electrolysis operation over a long period. This space sanitizing and cleaning device sanitizes and cleans the space around a housing 12 by discharging, out of the housing 12 from a discharge opening 20, air that has had dust removed therefrom by a dust removing filter 32 and that, as a result of passing through a sanitizing filter 76 which has absorbed electrolyzed hypochlorous acid water generated by an electrolyzed hypochlorous acid water generating device 60, contains hypochlorous acid volatilized from the electrolyzed hypochlorous acid water and has been brought into contact with the electrolyzed hypochlorous acid water through gas-liquid contact. The space sanitizing and cleaning device is characterized in that: electrodes 62 each comprise a titanium or a titanium alloy electrode body 62A and a catalyst layer 62B having a noble metal component adhered to the surface of the electrode body 62A; and a control means 64 executes control to conduct electrical current such that the current direction between the electrodes 62 reverses in an alternating manner with a period of non-current conduction sandwiched between the change of directions, and control to reverse the current conduction direction to the electrodes during the period of non-current conduction to the electrodes.

IPC Classes  ?

  • F24F 7/003 - Ventilation in combination with air cleaning
  • A61L 9/01 - Deodorant compositions
  • F24F 7/007 - Ventilation with forced flow
  • C02F 1/461 - Treatment of water, waste water, or sewage by electrochemical methods by electrolysis

28.

POLYIMIDE, VARNISH, AND FILM

      
Application Number JP2020034172
Publication Number 2021/049545
Status In Force
Filing Date 2020-09-09
Publication Date 2021-03-18
Owner
  • ENEOS CORPORATION (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Hasegawa Masatoshi
  • Ishii Junichi
  • Watanabe Daisuke

Abstract

This polyimide has a repeating unit represented by formula (1). [In the formula, R1represents a tetravalent group, and R2represents a divalent group. However, at least a portion of the instances of R1is a group represented by formula (2). In addition, of all the instances of R2, a portion is a group represented by formula (3) and the other portion is a group represented by formula (4).]

IPC Classes  ?

  • C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors

29.

FUEL CELL CATALYST COMPOSITION AND FUEL CELL CONTAINING SAME

      
Application Number JP2020025882
Publication Number 2021/010167
Status In Force
Filing Date 2020-07-01
Publication Date 2021-01-21
Owner TOYO UNIVERSITY (Japan)
Inventor Wada Noboru

Abstract

Provided is a fuel cell catalyst composition containing a C12A7:X-inorganic material having a structure in which oxygen anions in C12A7 are substituted with halogen (X) anions, or a C12A7:X-inorganic material in which C12A7:X-has been partially converted to an electride. Also provided is a fuel cell containing the fuel cell catalyst composition in a catalyst layer. Also provided is a method for producing the fuel cell catalyst composition, the method comprising a step for heat-treating C12A7:X- at 1,000–1,300°C in a nitrogen atmosphere for 20 hours or more.

IPC Classes  ?

  • H01M 4/88 - Processes of manufacture
  • H01M 4/90 - Selection of catalytic material
  • H01M 8/086 - Phosphoric acid fuel cells [PAFC]
  • H01M 8/10 - Fuel cells with solid electrolytes
  • B01J 27/138 - HalogensCompounds thereof with alkaline earth metals, magnesium, beryllium, zinc, cadmium or mercury

30.

GNIDIMACRIN DERIVATIVES AS POTENT HIV-1 INHIBITORS AND LATENCY REVERSING AGENTS

      
Application Number US2020038693
Publication Number 2020/257622
Status In Force
Filing Date 2020-06-19
Publication Date 2020-12-24
Owner
  • THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (USA)
  • DUKE UNIVERSITY (USA)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Lee, Kuo-Hsiung
  • Morris-Natschke, Susan
  • Cheng, Yung-Yi
  • Hsieh, Min-Tsang
  • Chen, Chin Ho
  • Huang, Li
  • Li, Wei
  • Asada, Yoshihisa
  • Koike, Kazuo
  • Liu, Qingbo

Abstract

Daphne odoraDaphne genkwaDaphne genkwa and methods of their use for activating latent HIV-1 replication and inhibiting HIV-1 infection are disclosed.

IPC Classes  ?

  • A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
  • A61K 38/49 - UrokinaseTissue plasminogen activator
  • A61K 9/00 - Medicinal preparations characterised by special physical form

31.

ANTI-INFECTIVE AGENT WITH REDUCED EFFECT OF VANCOMYCIN ON BONE FORMATION INHIBITION

      
Application Number JP2020023936
Publication Number 2020/256060
Status In Force
Filing Date 2020-06-18
Publication Date 2020-12-24
Owner TOHO UNIVERSITY (Japan)
Inventor
  • Tsuji Kentaro
  • Kimura Soichiro
  • Tateda Kazuhiro
  • Takahashi Hiroshi

Abstract

When closing a surgical suture during a spine surgery using a vancomycin powder, in order to prevent secondary infection due to MRSA, a high concentration of vancomycin is sprayed directly onto a bone for infection prevention purposes. In this case, however, inhibition of bone formation may occur. On the other hand, if the concentration of vancomycin is reduced in consideration of the inhibition of bone formation, sufficient infection prevention cannot be achieved. Therefore, it is desirable to provide a drug which does not cause inhibition of bone formation while maintaining a high vancomycin concentration. Provided is an anti-infective agent characterized by comprising vancomycin and active vitamin D or an active vitamin D derivative.

IPC Classes  ?

  • A61P 31/04 - Antibacterial agents
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 38/14 - Peptides containing saccharide radicalsDerivatives thereof
  • A61K 31/592 - 9,10-Secoergostane derivatives, e.g. ergocalciferol, vitamin D2
  • A61K 31/593 - 9,10-Secocholestane derivatives, e.g. cholecalciferol, vitamin D3

32.

NOVEL DIAMINE, NOVEL POLYIMIDE DERIVED THEREFROM, AND MOLDED BODY THEREOF

      
Application Number JP2020002024
Publication Number 2020/158523
Status In Force
Filing Date 2020-01-22
Publication Date 2020-08-06
Owner
  • HONSHU CHEMICAL INDUSTRY CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Ishii Junichi
  • Hasegawa Masatoshi

Abstract

The purpose of the present invention is to provide a diamine compound that can yield a resin that has both excellent solvent solubility (solution processability) and high heat resistance, a polyimide synthesized from said diamine compound and having excellent solution processability, and a molded body with high heat resistance obtained from said polyimide. This purposes met by the diamine compound represented in general formula (1).

IPC Classes  ?

  • C07C 217/90 - Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. amino-diphenylethers
  • C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors

33.

CANOE

      
Application Number JP2019041277
Publication Number 2020/085287
Status In Force
Filing Date 2019-10-21
Publication Date 2020-04-30
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Mochizuki Osamu
  • Kubota Yoshihiro

Abstract

The present invention improves the straight traveling performance and acceleration performance of a canoe. A canoe 1 includes a hull 2 including a ship bottom 2a and ship sides 2b, and a deck 3 covering the hull 2. The ship bottom 2a is formed to have an airfoil-shaped profile in a horizontal plane, such as a first curve c1, a second curve c2, and a third curve c3, and in a vertical plane parallel to the center line C-C of the ship bottom 2a. This airfoil shape improves the straight traveling performance when the canoe moves forward with respect to the water, and also improves the forward acceleration performance when the canoe moves backward with respect to the water.

IPC Classes  ?

34.

DISPLAY UPDATE DEVICE, DISPLAY UPDATE METHOD, PROGRAM, AND RECORDING MEDIUM

      
Application Number JP2019026298
Publication Number 2020/054185
Status In Force
Filing Date 2019-07-02
Publication Date 2020-03-19
Owner
  • NEC SOLUTION INNOVATORS, LTD. (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Hosokawa Yutaka
  • Goka Erika
  • Kawaguchi Hideo
  • Mashio Yuhei

Abstract

Provided is a system that allows a user to input an answer more smoothly. A display update device of the present invention is characterized by comprising a storage means, a display means, an input determination means, an elapsed time acquisition means, and an update means, wherein: the storage means stores a plurality of questions and an update time n; the display means displays, on a display unit, the question, an input area for an answer to the question, the input area being a touch panel; the input determination means determines start and end of a touch by the user on the input area; the elapsed time acquisition means acquires an elapsed time from the end of the touch; when the elapsed time reaches the update time n, the update means updates the display of the input area on the display unit to display of a new input area; and the update time n is set to a time that satisfies a predetermined expression.

IPC Classes  ?

  • G06F 3/0488 - Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures
  • G06F 3/041 - Digitisers, e.g. for touch screens or touch pads, characterised by the transducing means
  • G09B 7/02 - Electrically-operated teaching apparatus or devices working with questions and answers of the type wherein the student is expected to construct an answer to the question which is presented or wherein the machine gives an answer to the question presented by the student

35.

ANAMMOX BACTERIA POPULATION HOLDING CARRIER FOR TREATING WASTE WATER, ANAMMOX BACTERIA POPULATION ADHESION BODY, AND WASTE WATER TREATMENT DEVICE USING SAID ADHESION BODY

      
Application Number JP2018045854
Publication Number 2019/117243
Status In Force
Filing Date 2018-12-13
Publication Date 2019-06-20
Owner
  • TOYO UNIVERSITY (Japan)
  • TOYO TANSO CO., LTD. (Japan)
Inventor
  • Sumino Tatsuo
  • Sakuma Satoshi
  • Tojo Tetsuro
  • Ishikawa Ai
  • Nakazono Tomoya
  • Takeshita Masatoshi

Abstract

[Problem] To provide an anammox bacteria population holding carrier, an anammox population bacteria adhesion body, and a waste water treatment device which are capable of dramatically shortening a start period for obtaining a nitrogen removal rate of 1kg-N/m3/day. [Solution] An anammox bacteria population holding carrier according to the present invention is characterized by including carbon particles, wherein: the carbon particles are preferably graphite particles, in particular, isotropic graphite particles; a zeta-potential is preferably -35 mV to 0 mV; and the average particle size of the carbon particles is preferably 2 μm to 1000 μm.

IPC Classes  ?

  • C02F 3/10 - PackingsFillingsGrids
  • C02F 3/00 - Biological treatment of water, waste water, or sewage
  • C02F 3/34 - Biological treatment of water, waste water, or sewage characterised by the microorganisms used

36.

COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT STROKE

      
Application Number JP2018035650
Publication Number 2019/065718
Status In Force
Filing Date 2018-09-26
Publication Date 2019-04-04
Owner TOYO UNIVERSITY (Japan)
Inventor Kato Kazunori

Abstract

The present application provides a composition for the prevention, alleviation, and/or treatment of cytotoxicity of cells such as vascular endothelial cells due to heat stroke or heat stress in a subject and/or adverse events associated with the production and release of fever-induced inflammatory cytokines from blood cells due to heat stress, the composition containing at least one substance selected from the group consisting of auraptene, tangeretin, and medium-chain fatty acids as an active ingredient.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A23K 20/121 - Heterocyclic compounds containing oxygen or sulfur as hetero atom
  • A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
  • A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
  • A61K 36/752 - Citrus, e.g. lime, orange or lemon
  • A61P 3/00 - Drugs for disorders of the metabolism
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • A61K 131/00 - Containing or obtained from seeds, nuts, fruits or grains

37.

ACTUATOR AND MOVING BODY

      
Application Number JP2018017152
Publication Number 2018/207663
Status In Force
Filing Date 2018-04-27
Publication Date 2018-11-15
Owner
  • TOKYO INSTITUTE OF TECHNOLOGY (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Tsukagoshi Hideyuki
  • Terashima Koichi
  • Takai Yujiro

Abstract

This rotary actuator 100 is provided with an expandable balloon 102 which radially and axially expands by pressurization. The expandable balloon 102 is restrained such that the expandable balloon 102 hardly stretches in the direction along a helix 108 and hardly expands in a radial direction.

IPC Classes  ?

  • F15B 15/10 - Fluid-actuated devices for displacing a member from one position to anotherGearing associated therewith characterised by the construction of the motor unit the motor being of diaphragm type
  • A61M 25/082 - Self-propulsion arrangements

38.

ANTI-EPHA2 ANTIBODY AND IMMUNOLOGICAL DETECTION OF EPHA2 USING SAME

      
Application Number JP2018001730
Publication Number 2018/135653
Status In Force
Filing Date 2018-01-22
Publication Date 2018-07-26
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Kato Kazunori
  • Agatsuma Toshinori
  • Hasegawa Jun

Abstract

Provided is an EPHA2-specific antibody. A monoclonal antibody which contains a heavy-chain variable region comprising the amino acid sequence represented by SEQ ID NO: 20 and a light-chain variable region comprising the amino acid sequence represented by SEQ ID NO: 22 and which can bind specifically to EPHA2, or a functional fragment of the monoclonal antibody which can bind specifically to EPHA2; and a monoclonal antibody which contains a heavy-chain variable region comprising the amino acid sequence represented by SEQ ID NO: 15 and a light-chain variable region comprising the amino acid sequence represented by SEQ ID NO: 18 and which can bind specifically to EPHA2, or a functional fragment of the monoclonal antibody which can bind specifically to EPHA2.

IPC Classes  ?

  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C07K 16/46 - Hybrid immunoglobulins
  • C12P 21/08 - Monoclonal antibodies
  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
  • C12N 15/09 - Recombinant DNA-technology

39.

DRUG DELIVERY NANOPARTICLE COMPOSITION

      
Application Number JP2017011834
Publication Number 2017/164331
Status In Force
Filing Date 2017-03-23
Publication Date 2017-09-28
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Maekawa, Toru
  • Dasappan Nair, Sakthikumar
  • Mohamed, Sheikh Mohamed
  • Veeranarayanan, Srivani

Abstract

Provided is a low-cytotoxicity composition that can be applied to a drug delivery system enabling passage through the blood-brain barrier. A nanoparticle composition comprises nanoparticles to the surface of which a first substance and second substance having specificity for tumor cells are bonded, wherein: the first substance having specificity for tumor cells is a peptide containing an amino acid sequence of arginine—glycine—aspartic acid; the second substance having specificity for tumor cells is an iron-binding protein; the nanoparticles have an outer layer and a vesicle surrounded by the outer layer; and the nanoparticles contains, as membrane components, a PEGylated phospholipid, a fatty acid having a melting point of 30°C or higher, and a non-PEGylated phospholipid.

IPC Classes  ?

  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
  • A61K 49/00 - Preparations for testing in vivo
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61P 25/00 - Drugs for disorders of the nervous system
  • A61P 35/00 - Antineoplastic agents

40.

NOVEL TETRACARBOXYLIC DIANHYDRIDE, POLYIMIDE DERIVED FROM SAID TETRACARBOXYLIC DIANHYDRIDE, AND MOLDED ARTICLE PRODUCED FROM SAID POLYIMIDE

      
Application Number JP2016078448
Publication Number 2017/057360
Status In Force
Filing Date 2016-09-27
Publication Date 2017-04-06
Owner
  • HONSHU CHEMICAL INDUSTRY CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Ishii Junichi
  • Hasegawa Masatoshi

Abstract

The present invention addresses the problem of providing: a polyimide which is derived from a novel tetracarboxylic dianhydride, has both excellent solubility in various types of organic solvents and thermoplasticity and therefore has excellent processability, and also has both a low linear thermal expansion coefficient and high light permeability (transparency); and a molded article produced from the polyimide. The problem can be solved by a polyimide derived from a tetracarboxylic dianhydride represented by formula (1).

IPC Classes  ?

  • C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors
  • C07D 307/89 - Benzo [c] furansHydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

41.

NOVEL TETRACARBOXYLIC DIANHYDRIDE, AND POLYIMIDE AND POLYIMIDE COPOLYMER OBTAINED FROM SAID ACID DIANHYDRIDE

      
Application Number JP2016058182
Publication Number 2016/148150
Status In Force
Filing Date 2016-03-15
Publication Date 2016-09-22
Owner
  • TAOKA CHEMICAL CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Ishii, Junichi
  • Hasegawa, Masatoshi

Abstract

A tetracarboxylic dianhydride represented by formula (1), and a polyimide or polyimide copolymer produced from this tetracarboxylic dianhydride, are used. This makes it possible to provide a polyimide and a polyimide copolymer having exceptional solvent solubility (solvent processability) and heat resistance, as well as a polyimide film containing the same.

IPC Classes  ?

  • C07D 407/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
  • C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors
  • C08J 5/18 - Manufacture of films or sheets

42.

LEAFLET SIZER

      
Application Number JP2015086525
Publication Number 2016/111231
Status In Force
Filing Date 2015-12-28
Publication Date 2016-07-14
Owner
  • JAPANESE ORGANIZATION FOR MEDICAL DEVICE DEVELOPMENT, INC. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor Ozaki Shigeyuki

Abstract

The present invention provides a leaflet sizer comprising first and second commissure indication parts (11, 13) to be contacted with two commissures of a cardiac valve, the first and second commissure indication parts being movable relative to each other.

IPC Classes  ?

  • A61F 2/24 - Heart valves
  • A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof

43.

CARRIER FOR INCLUSIVE IMMOBILIZATION AND WASTEWATER TREATMENT DEVICE USING SAME

      
Application Number JP2015079563
Publication Number 2016/067970
Status In Force
Filing Date 2015-10-20
Publication Date 2016-05-06
Owner TOYO UNIVERSITY (Japan)
Inventor Sumino, Tatsuo

Abstract

A carrier for inclusive immobilization which is capable of carrying cells of a bacterium (for example, a nitrifying bacterium) at a higher concentration than conventional carriers and the specific gravity of which can be lowered compared with the conventional carriers while retaining the carrier strength so that a high reaction rate (for example, nitrification rate) can be achieved and power energy required for flowing the carrier in a wastewater treatment tank can be remarkably reduced. The carrier 12 for inclusive immobilization, said carrier being obtained by gelling an immobilization material by polymerizing in the presence of bacterial cells to thereby inclusively immobilize the bacterial cells in the immobilization material, wherein: the immobilization material is a swelling material that is nontoxic to the bacterial cells and swells by absorbing water; and the swelling material is contained at a concentration of 22-38 mass% relative to the carrier 12 and capable of swelling to a volume of 3.5 times or more of the volume of the carrier 12, is put into a wastewater treatment tank 14.

IPC Classes  ?

  • C02F 3/00 - Biological treatment of water, waste water, or sewage
  • C02F 3/08 - Aerobic processes using moving contact bodies
  • C02F 3/10 - PackingsFillingsGrids
  • C02F 3/34 - Biological treatment of water, waste water, or sewage characterised by the microorganisms used
  • C12N 11/02 - Enzymes or microbial cells immobilised on or in an organic carrier
  • C12N 11/04 - Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres

44.

TEMPLATE FOR FORMING VALVE LEAFLET

      
Application Number JP2015058338
Publication Number 2015/141798
Status In Force
Filing Date 2015-03-19
Publication Date 2015-09-24
Owner
  • JAPANESE ORGANIZATION FOR MEDICAL DEVICE DEVELOPMENT, INC. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor Ozaki Shigeyuki

Abstract

The present invention provides a template for obtaining a valve leaflet material for forming a valve leaflet that distributes stress applied thereto so that the valv leaflet can have increased tolerance. A template (13) having a valve leaflet base forming part (11) shaped corresponding to a valve leaflet base further has a wing forming part (15) located outside the valve leaflet base forming part (11) and corresponding to a wing portion. The wing forming part (15) has one or more holes located in an area corresponding to the contour of the wing portion or has a guide part located in the area corresponding to the contour of the wing portion.

IPC Classes  ?

  • A61F 2/24 - Heart valves
  • A61F 2/76 - Means for assembling, fitting, or testing prostheses, e.g. for measuring or balancing

45.

DYSPHONIA TREATMENT IMPLEMENT

      
Application Number JP2014083845
Publication Number 2015/111340
Status In Force
Filing Date 2014-12-22
Publication Date 2015-07-30
Owner TOHO UNIVERSITY (Japan)
Inventor Matsushima, Koji

Abstract

 Provided is a dysphonia treatment implement used for treating incomplete glottal closure by incising a window shape in the thyroid cartilage and moving affected vocal cords to the inside while bypassing the incised thyroid cartilage, the dysphonia treatment implement having a titanium plate as a fixing part for fixing at one end thereof to the thyroid cartilage, and a main body part capable of bending along bend lines drawn in at least two locations.

IPC Classes  ?

  • A61B 17/24 - Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or noseTongue scrapers
  • A61F 2/20 - LarynxesTracheae combined with larynxes or for use therewith

46.

POLYIMIDE AND MOLDED BODY THEREOF

      
Application Number JP2013075300
Publication Number 2014/046180
Status In Force
Filing Date 2013-09-19
Publication Date 2014-03-27
Owner
  • HONSHU CHEMICAL INDUSTRY CO., LTD. (Japan)
  • TOHO UNIVERSITY (Japan)
Inventor
  • Ishii Junichi
  • Hasegawa Masatoshi

Abstract

The present invention addresses the problem of providing: a polyimide which has excellent transparency, high heat resistance and low linear thermal expansion coefficient at the same time, while exhibiting solvent workability (excellent solubility and film formation performance) by means of a low moisture-absorbing solvent; and a method for producing this polyimide. In order to solve the above-mentioned problem, the present invention provides a polyimide that contains a constituent unit represented by formula (1). (In the formula, each R independently represents a hydrogen atom or an alkyl group having 1-6 carbon atoms, provided that at least one of two R groups bonded to a same benzene ring is an alkyl group.)

IPC Classes  ?

47.

METHOD AND DEVICE FOR TREATING AMMONIA NITROGEN-CONTAINING WATER AT LOW TEMPERATURE

      
Application Number JP2013069776
Publication Number 2014/017429
Status In Force
Filing Date 2013-07-22
Publication Date 2014-01-30
Owner TOYO UNIVERSITY (Japan)
Inventor Sumino, Tatsuo

Abstract

A method and a device are provided with which ammonia nitrogen-containing water can be stably treated even when the water temperature is 15ºC or lower. The method includes a nitrification step in which ammonia nitrogen-containing water having an ammonia nitrogen concentration of 1-300 mg/L is brought into contact with a carrier on which nitrifying bacteria have been preferentially propagated to such a degree that the bacteria are detected after 8-week cultivation in an ammonium sulfate solution having a concentration as high as 5,000 mg/L or above, in an aerobic environment at a temperature of 0-15ºC to thereby nitrify the ammonia contained in the ammonia nitrogen-containing water.

IPC Classes  ?

  • C02F 3/34 - Biological treatment of water, waste water, or sewage characterised by the microorganisms used
  • C02F 3/00 - Biological treatment of water, waste water, or sewage

48.

TOYO UNIVERSITY

      
Application Number 1171650
Status Registered
Filing Date 2013-05-31
Registration Date 2013-05-31
Owner Toyo University (Japan)
NICE Classes  ? 41 - Education, entertainment, sporting and cultural services

Goods & Services

Operating lotteries; educational and instruction services relating to arts, crafts, sports or general knowledge; providing information on donation of human corpses for medical education; arranging of donation of human corpses for medical education; arranging, conducting and organization of seminars; animal training; plant exhibitions; animal exhibitions; providing electronic publications; services of reference libraries for literature and documentary records; book rental; art exhibitions; gardens for public admission; caves for public admission; publication of books; arranging and planning of movies, shows, plays or musical performances; movie showing, movie film production, or movie film distribution; presentation of live show performances; direction or presentation of plays; presentation of musical performances; production of radio or television programs; production of videotape film in the fields of education, culture, entertainment or sports, not for movies or television programs and not for advertising or publicity; directing of radio and television programs; operation of video and audio equipment for the production of radio and television programs; organization, arranging and conducting of sports competitions; organization of entertainment events excluding movies, shows, plays, musical performances, sports, horse races, bicycle races, boat races and auto races; organization, arranging and conducting of horse races; organization, arranging and conducting of bicycle races; organization, arranging and conducting of boat races; organization, arranging and conducting of auto races; providing audio or video studio services; providing sports facilities; providing amusement facilities; providing facilities for movies, shows, plays, music or educational training; booking of seats for shows; rental of cinematographic machines and apparatus; rental of cine-films; rental of musical instruments; rental of sports equipment; rental of television sets; rental of radio sets; rental of records or sound-recorded magnetic tapes; rental of image-recorded magnetic tapes; rental of film negatives; rental of film positives; rental of toys; rental of amusement machines and apparatus; rental of game machines and apparatus; rental of paintings and calligraphic works; photography; language interpretation; translation; rental of cameras; rental of optical machines and instruments.

49.

TOYO UNIVERSITY

      
Application Number 163256300
Status Registered
Filing Date 2013-06-25
Registration Date 2019-07-09
Owner Toyo University (Japan)
NICE Classes  ?
  • 35 - Advertising and business services
  • 41 - Education, entertainment, sporting and cultural services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

(1) Operating lotteries; educational and instruction services, namely, providing courses of instruction at the kindergarten, elementary school, middle school, high school, undergraduate, graduate, post-graduate, and professional levels in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; providing information on donation of human corpses for medical education; arranging of donation of human corpses for medical education; arranging, conducting and organization of seminars in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; animal training; plant exhibitions; animal exhibitions; providing non-downloadable electronic publications in the nature of books, magazines, journals, scientific texts, textbooks, brochures, research papers, reports, and leaflets in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; services of reference libraries for literature and documentary records; book rental; art exhibitions; gardens for public admission; caves for public admission; publication of books; arranging and planning of movies, shows, plays or musical performances; movie showing, movie film production, or movie film distribution; presentation of live show performances; direction or presentation of plays; presentation of musical performances; production of radio or television programs; production of videotape film in the fields of education, culture, entertainment or sports, not for movies or television programs and not for advertising or publicity; directing of radio and television programs; operation of video and audio equipment for the production of radio and television programs, namely, microphones, video cameras, video monitors, audio speakers, mixers, amplifiers; organization, arranging and conducting of sports competitions; organization of entertainment events, namely, lectures, concerts, plays, exhibitions, performances, bazaars, excluding sports, horse races, bicycle races, boat races and auto races; organization, arranging and conducting of horse races; organization, arranging and conducting of bicycle races; organization, arranging and conducting of boat races; organization, arranging and conducting of auto races; providing audio or video studio services; providing sports facilities; providing amusement park facilities and sports facility; providing facilities for movies, shows, plays, music or educational training, namely, lectures, active learning programs, academic meetings, symposiums, conferences in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; booking of seats for shows; rental of cine-films; rental of musical instruments; rental of sports equipment; rental of television sets; rental of radio sets; rental of records or sound-recorded magnetic tapes; rental of image-recorded magnetic tapes; rental of film negatives; rental of film positives; rental of toys; rental of paintings and calligraphic works; photography; language interpretation; translation; rental of cameras; rental of optical machines and instruments, namely, cameras, video cameras, photographic equipment, telescopes, microscopes, and projectors. (2) Educational and instruction services, namely, providing courses of instruction at the kindergarten, elementary school, middle school, high school, undergraduate, graduate, post-graduate, and professional levels in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; arranging , conducting and organization of seminars in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; providing non-downloadable electronic publications in the nature of books, magazines, journals, scientific texts, textbooks, brochures, research papers, reports, and leaflets in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; services of reference libraries for literature and documentary records; book rental; publication of books.

50.

SCOLIOSIS EVALUATION SYSTEM AND EVALUATION INSTRUMENT APPLIED TO SAME SYSTEM

      
Application Number JP2012080860
Publication Number 2013/081030
Status In Force
Filing Date 2012-11-29
Publication Date 2013-06-06
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Akimoto, Toshinari
  • Terada, Nobuyuki

Abstract

The present invention comprises a three-dimensional sensor (100) which takes the back of a subject and acquires three-dimensional data thereon, a characteristic part designation unit (102) which designates a characteristic part of which the degree of curvature is to be measured with regard to the back of the subject, an uneven state detection unit (103) which detects an uneven state of a horizontal body surface based on the three-dimensional data with respect to the characteristic part designated using the characteristic part designation unit, and a display monitor (200) which displays a detection result acquired by the uneven state detection unit.

IPC Classes  ?

  • A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof

51.

TOYO UNIVERSITY

      
Serial Number 79134548
Status Registered
Filing Date 2013-05-31
Registration Date 2014-08-12
Owner Toyo University (Japan)
NICE Classes  ? 41 - Education, entertainment, sporting and cultural services

Goods & Services

[ Operating lotteries; ] educational services, namely, providing courses of instruction at the [ kindergarten, elementary school, middle school, high school, ] undergraduate, graduate, post-graduate, and professional levels in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; [ providing information on donation of human corpses for medical education; arranging of donation of human corpses for medical education; ] arranging, conducting and organization of seminars in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; [ animal training; plant exhibitions; animal exhibitions; ] providing non-downloadable electronic publications in the nature of books, magazines, journals, scientific texts, textbooks, brochures, research papers, reports, and leaflets in the fields of arts, crafts, sports, natural science, social science, humanities, and liberal arts; [ services of reference libraries for literature and documentary records; book rental; art exhibitions; gardens for public admission; caves for public admission; publication of books; arranging and planning of movies, shows, plays or musical performances; movie showing, movie film production, or movie film distribution; presentation of live show performances; direction or presentation of plays; presentation of musical performances; production of radio or television programs; production of videotape film in the fields of education, culture, entertainment or sports, not for movies or television programs and not for advertising or publicity; directing of radio and television programs; operation of video and audio equipment for the production of radio and television programs; organization, arranging and conducting of sports competitions; ] organization of entertainment events excluding movies, shows, plays, musical performances, sports, horse races, bicycle races, boat races and auto races [ ; organization, arranging and conducting of horse races; organization, arranging and conducting of bicycle races; organization, arranging and conducting of boat races; organization, arranging and conducting of auto races; providing audio or video studio services; providing sports facilities; providing amusement facilities; providing facilities for movies, shows, plays, music or educational training; booking of seats for shows; rental of cinematographic machines and apparatus; rental of cine-films; rental of musical instruments; rental of sports equipment, except vehicles; rental of television sets; rental of radio sets; rental of records or sound-recorded magnetic tapes; rental of image-recorded magnetic tapes; rental of film negatives; rental of film positives; rental of toys; rental of amusement machines and apparatus; rental of game machines and apparatus; rental of paintings and calligraphic works; photography; language interpretation; translation; rental of cameras; rental of optical machines and instruments, namely, cameras, video cameras, photographic equipment, telescopes, microscopes, and projectors ]

52.

AUTONOMIC NERVOUS FUNCTION EVALUATION DEVICE AND METHOD, AND COMPUTER PROGRAM

      
Application Number JP2011071161
Publication Number 2013/038552
Status In Force
Filing Date 2011-09-15
Publication Date 2013-03-21
Owner
  • PIONEER CORPORATION (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Terada, Nobuyuki
  • Akimoto, Toshinari
  • Goma, Masaki
  • Kimura, Yoshinori
  • Ito, Atsuya
  • Mori, Shuntaro

Abstract

The objective of the present invention is to evaluate autonomic nervous function with higher precision by detecting blood flow state. The autonomic nervous function evaluation device (10) is provided with: a detection means (12) for detecting the blood flow state of a subject when (i) the subject transitions, while holding breath, from a first position which is a position before stress is placed to cause a change in the blood flow state to a second position which is a position after stress is placed to cause a change in the blood flow state and (ii) the subject keeps holding breath for at least a prescribed amount of time after transitioning to the second position; and an evaluation means (14) for evaluating the autonomic nervous function of the subject on the basis of the blood flow state of the subject detected by the detection means.

IPC Classes  ?

53.

AUTONOMIC NERVOUS FUNCTION EVALUATION DEVICE AND METHOD, AND COMPUTER PROGRAM

      
Application Number JP2011071160
Publication Number 2013/038551
Status In Force
Filing Date 2011-09-15
Publication Date 2013-03-21
Owner
  • PIONEER CORPORATION (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Terada, Nobuyuki
  • Akimoto, Toshinari
  • Goma, Masaki
  • Kimura, Yoshinori
  • Ito, Atsuya
  • Mori, Shuntaro

Abstract

The objective of the present invention is to evaluate autonomic nervous function with higher precision by detecting blood flow state. The autonomic nervous function evaluation device (10) is provided with: a detection means (12) for detecting the blood flow state of a subject when the subject transitions from a first position to a second position which is a position after stress is placed to cause a change in the blood flow state, after the subject has maintained, for at least a prescribed amount of time, the first position which is a position before stress is placed to cause a change in the blood flow state; and an evaluation means (14) for evaluating the autonomic nervous function of the subject on the basis of the blood flow state of the subject detected by the detection means.

IPC Classes  ?

54.

ANTIARRHYTHMIC DRUG, ATRIAL FIBRILLATION INHIBITOR, MODEL OF SUSTAINED ATRIAL FIBRILLATION AND METHOD FOR PRODUCING SAME, AND METHOD FOR SCREENING ATRIAL FIBRILLATION INHIBITOR

      
Application Number JP2012061314
Publication Number 2012/147902
Status In Force
Filing Date 2012-04-27
Publication Date 2012-11-01
Owner Toho University (Japan)
Inventor Sugiyama, Atsushi

Abstract

An atrial fibrillation inhibitor comprising a compound represented by any of structural formulae (I) to (VI) or a pharmacologically acceptable salt thereof and inhibiting atrial fibrillation. Structural formula (I) Structural formula (II) Structural formula (III) Structural formula (IV) Structural formula (V) Structural formula (VI) In structural formula (III), Gluc represents glucuronic acid.

IPC Classes  ?

  • A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
  • A01K 67/027 - New or modified breeds of vertebrates
  • A61K 31/231 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
  • A61P 9/06 - Antiarrhythmics
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

55.

CELL-ADHERING LIGHT-CONTROLLABLE SUBSTRATE

      
Application Number JP2012059880
Publication Number 2012/141202
Status In Force
Filing Date 2012-04-11
Publication Date 2012-10-18
Owner
  • Toho University (Japan)
  • HITACHI HIGH-TECHNOLOGIES CORPORATION (Japan)
Inventor
  • Furuta Toshiaki
  • Suzuki Akinobu
  • Sugiyama Hisashi
  • Ozawa Satoshi
  • Tada Hiroko

Abstract

The purpose of the present invention is to enable the analysis, separation, and incubation of cells in an alive state to be more easily conducted in a real-time manner, to enable the incubation to be conducted while removing unnecessary cells from the incubated cells to thereby heighten the purity, and to separate desired cells through analysis from the incubated cells to thereby heighten the purity, recovery, and viability of the desired cells. Cell images can be detected and analyzed and information on the location of desired cells can be obtained, by use of a cell-adhering light-controllable substrate which is characterized in that a photodissociable group including a coumarinylmethyl framework dissociates upon light irradiation to release a cell-adhering material and allow a cell-abhering material to remain. Furthermore, use of the substrate makes it possible to analyze and separate cells in an alive state on the basis of the location information thus obtained.

IPC Classes  ?

  • C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
  • C12M 1/00 - Apparatus for enzymology or microbiology
  • C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
  • C12N 1/02 - Separating microorganisms from their culture media

56.

CLASS D AMPLIFIER

      
Application Number JP2011053730
Publication Number 2011/118311
Status In Force
Filing Date 2011-02-21
Publication Date 2011-09-29
Owner TOYO UNIVERSITY (Japan)
Inventor Sano, Yuji

Abstract

A class D amplifier is provided with a signal inverter (3) for generating an inverted signal inverting an input signal from a signal source (1); a first pulse width modulator (4) for applying pulse width modulation to the input signal from the signal source (1); a second pulse width modulator (5) for applying pulse width modulation to the inverted signal; a first lowpass filter (6) for passing only the low frequency component of the pulse width modulated signal from the first pulse width modulator (4); and a second lowpass filter (7) for passing only the low frequency component of the pulse width modulated signal from the second pulse width modulator (5); wherein the signal from the first lowpass filter (6) and the signal from the second lowpass filter (7) are output to a load (8).

IPC Classes  ?

  • H03F 3/217 - Class D power amplifiersSwitching amplifiers

57.

SIGNAL LINE DRIVING CIRCUIT

      
Application Number JP2010067454
Publication Number 2011/046044
Status In Force
Filing Date 2010-10-05
Publication Date 2011-04-21
Owner TOYO UNIVERSITY (Japan)
Inventor Sano, Yuji

Abstract

A signal line driving circuit, which is operative to drive a signal line group (100) including at least a set of adjacent signal lines, comprises a plurality of signal voltage sources (10, 20) for outputting signal voltages to the respective signal lines included in the signal line group (100). The signal line driving circuit drives the signal line group (100) in such a manner that the adjacent signal lines (101, 102), which are included in the signal line group (100) and adjacent to each other, do not simultaneously exhibit voltage transitions in the opposite directions or that the time interval during which the adjacent signal lines (101, 102) simultaneously exhibit voltage transitions in the opposite directions is half or shorter than the time interval during which the adjacent signal lines (101, 102) exhibit respective voltage transitions.

IPC Classes  ?

  • G09G 3/20 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix
  • G09G 3/28 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix using controlled light sources using luminous gas-discharge panels, e.g. plasma panels

58.

ORGANIC THIN FILM TRANSISTOR AND SEMICONDUCTOR INTEGRATED CIRCUITS

      
Application Number JP2010050491
Publication Number 2010/116768
Status In Force
Filing Date 2010-01-18
Publication Date 2010-10-14
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Wada, Yasuo
  • Toyabe, Toru
  • Tsutsui, Ken

Abstract

Disclosed is an organic thin film transistor which comprises: an organic semiconductor layer; a source electrode and a drain electrode which are arranged at a distance from each other and respectively in contact with the organic semiconductor layer; a gate insulating film which is in contact with the organic semiconductor layer between the source electrode and the drain electrode; and a gate electrode which is in contact with the gate insulating film, while facing the organic semiconductor layer. In the organic thin film transistor, the impurity concentration of a high concentration region of the organic semiconductor layer, said high concentration region being positioned near the source electrode, is set higher than the impurity concentration of a low concentration region of the organic semiconductor layer, said low concentration region being positioned between the source electrode and the drain electrode above the gate electrode in the film thickness direction of the organic semiconductor layer.

IPC Classes  ?

  • H01L 29/786 - Thin-film transistors
  • H01L 51/05 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for rectifying, amplifying, oscillating or switching and having at least one potential-jump barrier or surface barrier; Capacitors or resistors with at least one potential-jump barrier or surface barrier

59.

CHOLESTEROL OXIDASE, CHROMOBACTERIUM SP. MICROBES, MEASUREMENT REAGENT, TESTING METHOD, GENE CODING FOR CHOLESTEROL OXIDASE, RECOMBINATION VECTOR, TRANSFORMANTS, AND CHOLESTEROL OXIDASE MANUFACTURING METHOD

      
Application Number JP2009052930
Publication Number 2009/104698
Status In Force
Filing Date 2009-02-19
Publication Date 2009-08-27
Owner TOYO UNIVERSITY (Japan)
Inventor Doukyu, Noriyuki

Abstract

Cholesterol oxidase produced from Chromobacterium sp. DS1 (FERM BP-11092) strain.

IPC Classes  ?

  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
  • C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
  • C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
  • G01N 33/573 - ImmunoassayBiospecific binding assayMaterials therefor for enzymes or isoenzymes

60.

RADIOMETRIC TEMPERATURE MEASURING METHOD AND RADIOMETRIC TEMPERATURE MEASURING SYSTEM

      
Application Number JP2008072518
Publication Number 2009/081748
Status In Force
Filing Date 2008-12-11
Publication Date 2009-07-02
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Iuchi, Tohru
  • Hiraka, Kensuke

Abstract

Disclosed are a radiometric temperature measuring method and a radiometric temperature measuring system (10). A thin film (2) is formed on a substrate (1). The polarized radiation luminance component emitted from the thin film (2) is measured in a range of angle ϑeic where the emissivity does not vary. From the result of the measurement of the polarized radiation luminance component, the temperature of the thin film (2) is calculated. The polarized radiation luminance component is a p-wave polarized radiation luminance component polarized by a polarizer (3), and the p-wave polarized radiation luminance component is measured by means of a radiometer (4). A pseudo-black body (5) is disposed in a position mirror-symmetrical with respect to the radiometer (4). The radiometer (4) is shielded against the background radiation. The temperature of the pseudo-black body (5) is measured, and the measured temperature is taken into consideration in the calculation of the temperature of the thin film (2).

IPC Classes  ?

  • G01J 5/00 - Radiation pyrometry, e.g. infrared or optical thermometry

61.

METHOD FOR DECOMPOSING CARBON-CONTAINING COMPOUND, METHOD FOR PRODUCING CARBON MICROSTRUCTURE, AND METHOD FOR FORMING CARBON THIN FILM

      
Application Number JP2008065095
Publication Number 2009/028451
Status In Force
Filing Date 2008-08-25
Publication Date 2009-03-05
Owner TOYO UNIVERSITY (Japan)
Inventor
  • Maekawa, Toru
  • Fukuda, Takahiro
  • Fukuda, Nami
  • Hasumura, Takashi
  • Ishii, Koji
  • Rantonen, Nyrki
  • Nakajima, Yoshikata
  • Hanajiri, Tatsuro

Abstract

Disclosed is a method for decomposing a carbon-containing compound, wherein a carbon-containing compound is decomposed by light irradiation. The carbon-containing compound is an organic compound, and light irradiation is performed while converting the carbon-containing compound into a subcritical fluid, a critical fluid or a supercritical fluid. This method enables to obtain a carbon microstructure such as a carbon nanoparticle at a temperature lower than those in conventional methods.

IPC Classes  ?

  • C01B 31/02 - Preparation of carbon; Purification
  • B01J 3/00 - Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matterApparatus therefor
  • B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves

62.

BEAM PROCESSING APPARATUS AND BEAM MONITORING APPARATUS

      
Application Number JP2008056598
Publication Number 2008/123550
Status In Force
Filing Date 2008-04-02
Publication Date 2008-10-16
Owner
  • HIRAIDE PRECISION CO., LTD. (Japan)
  • TOYO UNIVERSITY (Japan)
  • NAGANO PREFECTURE (Japan)
Inventor
  • Masuzawa, Tsuneaki
  • Tanaka, Fumitoshi
  • Yamazaki, Tomohiro
  • Yoshida, Yoshikazu
  • Ikeda, Hiromichi
  • Oguchi, Keigo
  • Yamagishi, Hikaru
  • Wakabayashi, Yuji
  • Kobayashi, Kouji

Abstract

Provided is a beam processing apparatus or a beam monitoring apparatus which has reduced sizes and reduced cost. The beam processing apparatus or the beam monitoring apparatus is provided with a beam outputting source; a beam passing member (25), which has an outputting section (25a) for outputting a beam toward a work (2) and permits the beam traveling toward the work (2) from the beam outputting source to pass through; a fixed member (6), which has a fixing surface (6a) for fixing the work (2) and moves in a prescribed direction; and a hollow member (23), which is formed hollow to be deformed in three-dimensional directions and has the beam passing member (25) inside. The hollow member (23) is composed of at least a first hollow member (26) and a second hollow member (27) connected to each other. At one end of the hollow member (23), an opening section (37) is formed, the one end of the hollow member (23) abuts to the fixing surface, and inside the hollow member (23) is in a vacuum state.

IPC Classes  ?

  • H01J 37/30 - Electron-beam or ion-beam tubes for localised treatment of objects
  • H01J 37/16 - VesselsContainers
  • H01J 37/20 - Means for supporting or positioning the object or the materialMeans for adjusting diaphragms or lenses associated with the support
  • H01J 37/317 - Electron-beam or ion-beam tubes for localised treatment of objects for changing properties of the objects or for applying thin layers thereon, e.g. ion implantation

63.

WETTING AGENT FOR ASBESTOS REMOVAL AND METHOD OF REMOVING ASBESTOS WITH THE SAME

      
Application Number JP2007070486
Publication Number 2008/047924
Status In Force
Filing Date 2007-10-19
Publication Date 2008-04-24
Owner
  • TOYO UNIVERSITY (Japan)
  • SAN-EI GEN F.F.I., INC. (Japan)
  • FORTY FIVE CO., LTD. (Japan)
Inventor
  • Shimomura, Koichiro
  • Nakamura, Hiroshi
  • Omoto, Toshio
  • Hishinuma, Naofumi

Abstract

A method of asbestos removal which is effective in stripping off an asbestos coating layer while preventing asbestos fibers from flying off into the air; and a wetting agent for asbestos removal which is for use in the method. The wetting agent for asbestos removal comprises a composition comprising Gellan gum and water, preferably a water-swollen Gellan gum liquid obtained by swelling Gellan gum with water. The method comprises wetting an asbestos coating layer with the wetting agent for asbestos removal to the depth of the layer and then stripping off the asbestos coating layer. Thus, the asbestos coating layer can be easily stripped off while preventing asbestos fibers from flying off into the air.

IPC Classes  ?

  • C09K 3/22 - Materials not provided for elsewhere for dust-laying or dust-absorbing

64.

BEAM MACHINING APPARATUS AND BEAM OBSERVING APPARATUS

      
Application Number JP2007067704
Publication Number 2008/032725
Status In Force
Filing Date 2007-09-12
Publication Date 2008-03-20
Owner
  • HIRAIDE PRECISION CO., LTD. (Japan)
  • TOYO UNIVERSITY (Japan)
  • NAGANO PREFECTURE (Japan)
Inventor
  • Masuzawa, Tsuneaki
  • Tanaka, Fumitoshi
  • Yamazaki, Tomohiro
  • Moriya, Toshihiro
  • Yoshida, Yoshikazu
  • Ikeda, Hiromichi
  • Oguchi, Keigo
  • Yamagishi, Hikaru
  • Wakabayashi, Yuji
  • Kobayashi, Kouji

Abstract

A beam machining apparatus (1) is provided with a beam outputting source (13) for outputting a beam for machining a work (2); a vacuum chamber (3) having a first channel (34) where the beam outputted from the beam outputting source (13) passes through; a local vacuum chamber (27), which has a second channel (40) connected to the first channel (34) for passing through the beam passed through the first channel (34), and an outputting port (78a) for outputting the beam toward the work (2); and a detecting means arranged on the outputting port (78a) or the like with a member (53) to be irradiated, for detecting the beam irradiation position. Thebeam machining apparatus (1) performs machining to the work (2) which is at least partially arranged under the external atmospheric pressure of the vacuum chamber (3) and the local vacuum chamber (27).

IPC Classes  ?

  • H01J 37/30 - Electron-beam or ion-beam tubes for localised treatment of objects
  • B23K 15/00 - Electron-beam welding or cutting
  • B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring
  • B23K 26/08 - Devices involving relative movement between laser beam and workpiece
  • B23K 26/42 - Preliminary treatment; Auxiliary operations or equipment (B23K 26/16 takes precedence);;
  • G21K 5/04 - Irradiation devices with beam-forming means
  • H01J 37/16 - VesselsContainers
  • H01J 37/317 - Electron-beam or ion-beam tubes for localised treatment of objects for changing properties of the objects or for applying thin layers thereon, e.g. ion implantation

65.

MEDICINAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION

      
Application Number JP2007052740
Publication Number 2007/094413
Status In Force
Filing Date 2007-02-15
Publication Date 2007-08-23
Owner
  • TOYO UNIVERSITY (Japan)
  • SUMITOMO RUBBER INDUSTRIES, LTD. (Japan)
  • SAN-EI GEN F.F.I., INC. (Japan)
Inventor
  • Shimomura, Koichiro
  • Nakamura, Hironobu
  • Yamamoto, Katsushi
  • Omoto, Toshio
  • Ojima, Naoto

Abstract

It is intended to provide a medicinal composition for transdermal administration which has a favorable texture in using and exerts an excellent therapeutic effect on skin ulcer such as bedsores. A hydrogel type composition, which is prepared by combining (i) an aqueous hypochlorous acid solution with (ii) native gellan gum, is used as a medicinal composition for transdermal administration.

IPC Classes  ?

  • A61K 33/20 - Elemental chlorineInorganic compounds releasing chlorine
  • A61K 9/06 - OintmentsBases therefor
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
  • A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

66.

SPINDLE MOTOR AND INFORMATION RECORDING/REPRODUCING DEVICE

      
Application Number JP2006324147
Publication Number 2007/094112
Status In Force
Filing Date 2006-12-04
Publication Date 2007-08-23
Owner
  • SEIKO INSTRUMENTS INC. (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Hirata, Masakazu
  • Oumi, Manabu
  • Chiba, Norio
  • Nakajima, Kunio
  • Iijima, Ryuji
  • Ohkubo, Toshifumi

Abstract

A spindle motor is provided with a shaft arranged along a rotating axis; a stator plate (16) for supporting the shaft; a rotating body rotatably inserted into the shaft; a rotor plate (19) which has an opposing plane (19a) opposing the stator plate and rotates with the rotating body; a plurality of rotor electrode sections (25) arranged on the opposing plane of the rotor plate at every prescribed angle (&thetas;1); a plurality of stator electrode sections (26) arranged on the surface of the stator plate at every angle (&thetas;2) which is narrower than the prescribed angle (&thetas;1); and a voltage applying means for rotating the rotor plate in a constant direction by a static force by applying a driving voltage to the selected stator electrode section. The rotor electrode sections are previously grounded.

IPC Classes  ?

  • H02N 1/00 - Electrostatic generators or motors using a solid moving electrostatic charge carrier
  • G11B 19/20 - DrivingStartingStoppingControl thereof

67.

SPINDLE MOTOR AND INFORMATION RECORDING/REPRODUCING DEVICE

      
Application Number JP2006324150
Publication Number 2007/094113
Status In Force
Filing Date 2006-12-04
Publication Date 2007-08-23
Owner
  • SEIKO INSTRUMENTS INC. (Japan)
  • TOYO UNIVERSITY (Japan)
Inventor
  • Hirata, Masakazu
  • Oumi, Manabu
  • Chiba, Norio
  • Nakajima, Kunio
  • Iijima, Ryuji
  • Ohkubo, Toshifumi

Abstract

A spindle motor is provided with a shaft arranged along a rotating axis; a stator plate (16) for supporting the shaft; a rotating body rotatably inserted into the shaft; a rotor plate (19) which has an opposing plane (19a) opposing the stator plate and rotates with the rotating body; a plurality of rotor electrode sections (25) arranged on the opposing plane of the rotor plate at every prescribed angle (&thetas;1); a plurality of stator electrode sections (26) arranged on the surface of the stator plate at every angle (&thetas;2) which is narrower than a prescribed angle; a voltage applying means for rotating the rotor plate in a constant direction by a static force by applying a driving voltage to the selected stator electrode section; and a dynamic pressure groove (23) which is arranged on the opposing plane of the rotor plate and generates a pressure in a direction of separating the rotor plate from the stator plate. The rotor electrode sections are previously grounded.

IPC Classes  ?

  • H02N 1/00 - Electrostatic generators or motors using a solid moving electrostatic charge carrier
  • G11B 19/20 - DrivingStartingStoppingControl thereof
  • H02K 7/08 - Structural association with bearings