Abstract

Methods and materials for recombinantly producing apocarotenoids from transgenic plants, and more particularly, tomato and potato plants, expressing heterologous genes from Crocus sativus, the saffron plant, under the control of specific promoters. Moreover, the genetic constructs including the heterologous genes are also related, and the use thereof for the expression in plants and to a method for obtaining transgenic plants which express the genetic construct mentioned above, and which have a high concentration of apocarotenoids products, in particular crocins and picrocrocins. Furthermore, the the food products obtained from such transgenic plants are also related, nutraceutical and pharmaceutical compositions including thereof and the use of such compositions as medicine, preferably for the treatment of neurodegenerative diseases such as Alzheimer's disease.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

The present invention relates to biomarkers and methods for use thereof in the diagnosis and/or prognosis of Alzheimer's disease (AD). More specifically, it relates to the use of a panel of biomarkers in an in vitro method in which the expression levels of said panel of biomarkers in a biological sample from a subject are indicative of the subject's risk of developing the disease.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
• G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

The invention relates to an electroabsorption unit for treating gas streams contaminated with volatile organic compounds and odourants, wherein the unit combines an absorption column in the upper part with an electrochemical cell in the lower part, both parts being adjacent and in contact by means of a grate for supporting the filling of the absorption column. The lower cover of the electrochemical cell also includes conductive supports to connect a source of electromotive force to electrodes. The gas to be degraded enters through the interface at the support grate and rises through the column against the current of the liquid phase.

IPC Classes  ?

• B01D 53/14 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
• B01D 53/32 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by electrical effects other than those provided for in group

Goods & Services

Training; Coaching [training]; Vocational training services; Education services relating to health; Education and instruction; Workshops for training purposes; Conducting of courses; Training and instruction; Employment training; Arranging of training courses; Arranging of workshops; Educational research; Education services relating to vocational training; Arranging technical instruction courses; Organisation of seminars relating to training; Staff training services; Consultancy services relating to training; Life coaching (training); Vocational skills training; Training relating to employment skills; Practical training [demonstration].

Abstract

A method for modulating green character of wine, as well as wine obtainable according to the method also relates to the use of a vine-shoot material as winemaking additive for modulating green character in wine, wherein the vine-shoot material is toasted vine-shoot material. The method includes the steps of providing a vine-shoot material, which is subjected to heating at a predetermined temperature during a period in the range from 30 to 120 minutes; and subjecting a fermentable mixture to fermentation, wherein a determined concentration of the vine-shoot material results from the heating step.

IPC Classes  ?

• C12G 1/022 - Fermentation; Microbiological or enzymatic treatment
• C12H 1/22 - Ageing or ripening by storing, e.g. lagering of beer

Abstract

The present invention discloses a hybrid material for detecting acid and base vapours, said material comprising a metal-organic framework and at least one colouring agent encapsulated in the pores of said metal-organic framework having proton transfer processes. The present invention further relates to a method for manufacturing said material and its use for detecting acid and base vapours.

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• G01N 21/76 - Chemiluminescence; Bioluminescence
• C07F 3/06 - Zinc compounds

Abstract

2 in an NaOH aqueous solution, directly on the free surface of the liquid phase.

IPC Classes  ?

• C01D 7/07 - Preparation from the hydroxides
• B01D 53/14 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
• B01D 53/18 - Absorbing units; Liquid distributors therefor
• B01D 53/34 - Chemical or biological purification of waste gases
• B01D 53/62 - Carbon oxides
• B01D 53/78 - Liquid phase processes with gas-liquid contact
• B01F 27/112 - Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
• B01F 35/53 - Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components

Abstract

The present invention relates to a system (1, 100) for inspecting and/or treating a surface which substantially extends on a plane being parallel to a X-Y plane. The system (1, 100) comprises: mobile means (8; 101, 102, 103, 104) which is movable according to a second axis (Y); a first mobile first side pulley (9) and a second mobile first side pulley (10) which are connected with said mobile means (8; 101, 102, 103, 104) and placed in said X-Y plane at a first side of said mobile means (8; 101, 102, 103, 104); a first mobile second side pulley (1 1 ) and a second mobile second side pulley (12) which are connected with said mobile means (8; 101, 102, 103, 104) and placed in said X-Y plane at a second side of said mobile means (8; 101, 102, 103, 104); a first fixed first side pulley (2), a second fixed first side pulley (3), a third fixed first side pulley (4) and a fourth fixed first side pulley (5) placed in said X-Y plane at said first side; a first fixed second side pulley (6) and a second fixed second side pulley (7) which are placed in said X-Y plane at said second side; a carrier (13) for transporting at least one inspecting device and/or said at least one treating device, wherein said carrier (13) is movable according to a first axis (X); a first cable (14) which is connected with said carrier (13) and sequentially wound on the second mobile first side pulley (10), the third fixed first side pulley (4), the second fixed first side pulley (3), the first fixed second side pulley (6), the first mobile second side pulley (1 1 ) such as to form a first closed loop; a second cable (15) which is connected with said carrier (13) and sequentially wound on the second mobile second side pulley (12), the second fixed second side pulley (7), the fourth fixed first side pulley (5), the first fixed first side pulley (2), the first mobile first side pulley (9) such as to form a second closed loop; first motor means for making said first cable (14) move in one direction or in the opposite direction; and second motor means for making said second cable (15) move in one direction or in the opposite direction; wherein the first fixed first side pulley (2), the third fixed first side pulley (4), the first mobile first side pulley (9), the second mobile first side pulley (10), the first fixed second side pulley (6), the second fixed second side pulley (7), the first mobile second side pulley (1 1 ) and the second mobile second side pulley (12) are placed such that said first cable (14) and said second cable (15) remain stationary when said first motor means and said second motor means are inactive and said first cable (14) and said second cable (15) are stationary.

IPC Classes  ?

• B25J 9/00 - Programme-controlled manipulators
• B25J 9/02 - Programme-controlled manipulators characterised by movement of the arms, e.g. cartesian co-ordinate type

Abstract

The invention relates to a new kind of electrocatalyst to be incorporated as part of the electrodes, anode and cathode, in water electrolysers aimed for hydrogen production through the electrochemical splitting of water into oxygen and hydrogen. The electrocatalyst is characterized by a layered and porous structure that provides a high performance towards the oxygen evolution reaction in the absence of added ionomer. The object of the invention is framed in the field of energy.

IPC Classes  ?

• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
• C25B 11/032 - Gas diffusion electrodes
• C25B 11/053 - Electrodes comprising one or more electrocatalytic coatings on a substrate characterised by multilayer electrocatalytic coatings
• C25B 11/055 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material
• C25B 11/061 - Metal or alloy
• C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound

Abstract

The invention relates to a new kind of electrocatalyst to be incorporated as part of the electrodes, anode and cathode, in water electrolysers aimed for hydrogen production through the electrochemical splitting of water into oxygen and hydrogen. The electrocatalyst is characterized by a layered and porous structure that provides a high performance towards the oxygen evolution reaction in the absence of added ionomer. The object of the invention is framed in the field of energy.

IPC Classes  ?

• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
• C25B 11/032 - Gas diffusion electrodes
• C25B 11/053 - Electrodes comprising one or more electrocatalytic coatings on a substrate characterised by multilayer electrocatalytic coatings
• C25B 11/055 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material
• C25B 11/061 - Metal or alloy
• C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound

Abstract

The invention provides methods and materials for recombinantly producing apocarotenoids from transgenic plants, and more particularly, tomato and potato plants, expressing heterologous genes from Crocus sativus, the saffron plant, under the control of specific promoters. Moreover, the present disclosure also relates to the genetic constructs comprising the heterologous genes, and the use thereof for the expression in plants and to a method for obtaining transgenic plants which express the genetic construct mentioned above, and which have a high concentration of apocarotenoids products, in particular crocins and picrocrocins. Furthermore, the present disclosure also refers to the food products obtained from such transgenic plants, nutraceutical and pharmaceutical compositions comprising thereof and the use of such compositions as medicine, preferably for the treatment of neurodegenerative diseases such as Alzheimer's disease.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 9/10 - Transferases (2.)
• C12P 7/44 - Polycarboxylic acids

Abstract

The present invention relates to a new methodology for obtaining hybrid nanomaterials from different materials with the potential to be exfoliated into 2D laminates using a ball milling methodology and, furthermore, functionalizing these materials during their synthesis with metallic nanoparticles at room temperature and with a simple and environmentally friendly methodology.

IPC Classes  ?

• C01B 32/21 - After-treatment
• C01G 39/06 - Sulfides
• C01G 41/00 - Compounds of tungsten
• C01G 49/00 - Compounds of iron

Goods & Services

Application processors; Computer software applications, downloadable; Office and business applications; Application development software; Web application and server software; Computer software for application and database integration; Application software for cloud computing services; Software; Science software.

Abstract

The present invention relates to biomarkers and methods for use in the diagnosis and/or prognosis of Alzheimer's disease (AD). More specifically, the present invention relates to the use of a biomarker panel in an in vitro method wherein the expression levels of said biomarker panel in a biological sample from a patient are indicative of the risk of the patient developing the disease .

IPC Classes  ?

• G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
• G01N 33/577 - Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies

Abstract

The present invention relates to the use of a guanylated fluorphore as a sulfate sensor and more in particular it relates to a method for selectively detecting and, optionally, quantifying sulfate anions in an aqueous sample by fluorescence spectroscopy using a guanylated fluorophore comprising a fluorescent group, containing a substituted or unsubstituted planar fluorescent core, and a guanidinyl moiety. The present invention also relates to a guanylated fluorophore comprising a fluorescent group and a guanidinyl moiety, wherein the fluorescent group is a fluorenyl group and the guanidinyl moiety is an alkyl substituted guanidinyl group. The present invention also relates to method for preparing such a guanylated fluorophore.

IPC Classes  ?

• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
• G01N 33/84 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH

Abstract

The present invention relates to a method for manufacturing hybrid photocatalysts or nanocomposites comprising titanium oxide and few-layer graphene nanoparticles with catalytic properties for the photodegradation of organic pollutants in aqueous solutions. Said invention fits perfectly in the chemical and chemical technology sectors and belongs to the field of environmental engineering; specifically, the application thereof will involve the treatment of aqueous effluents contaminated with herbicides and pesticides.

IPC Classes  ?

• B01J 21/06 - Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
• B01J 21/18 - Carbon

Abstract

The present invention relates to a method for modulating green character of wine, as well as wine obtainable according to said method. It also relates to the use of a vine-shoot material as winemaking additive for modulating green character in wine, wherein the vine-shoot material is toasted vine-shoot material.

IPC Classes  ?

• C12G 1/022 - Fermentation; Microbiological or enzymatic treatment

Abstract

The present invention refers to a carbonator reactor (101, 201) comprising a cylindrical body, a nozzle adapted for supplying a gas stream, inside the carbonator reactor (1) and above the surface of a liquid phase and wherein the nozzle is located at the top of the reactor body, an inlet, an outlet, means for regulating the temperature and the pressure, a stirring system and at least one baffle adapted to regulate the stirring of the liquid phase and the mass transfer of the gas into the liquid surface, at least one impeller comprising inclined blades wherein said blades make an angle from 5º to 60º with respect to the vertical axis Said reactor is suitable for the preparation of sodium carbonate and has a configuration that favours the mass transfer of a gas phase in a liquid phase. Furthermore, the present invention also relates to a method for the preparation of sodium carbonate by means of the carbonator reactor (101, 201) by capturing CO2 in an NaOH aqueous solution, directly on the free surface of the liquid phase.

IPC Classes  ?

• B01D 53/62 - Carbon oxides
• B01D 53/78 - Liquid phase processes with gas-liquid contact
• B01J 19/00 - Chemical, physical or physico-chemical processes in general; Their relevant apparatus
• B01J 19/18 - Stationary reactors having moving elements inside
• C01D 7/07 - Preparation from the hydroxides

Goods & Services

Courses (Training -) relating to science; Conducting of educational courses in science; Organisation of conferences and symposia in the field of medical science; Publication of documents in the field of training, science, public law and social affairs. Advisory services relating to science; Research services. Legal services.

Abstract

FlaviviridaeFlaviviridae family.

IPC Classes  ?

• A61P 31/14 - Antivirals for RNA viruses
• A61K 31/4178 - 1,3-Diazoles not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin

Abstract

The present invention relates to methods, devices and systems which allow calculating, transmitting and executing a reintroduction manoeuvre for reintroducing an aircraft which, as it moves following a descent path to runway in a series of aircrafts separated from one another following said path, must abort the landing in the final step of the approach to runway, wherein a fundamental aspect consists of determining the existence of a gap in the descent path in which it is possible to reintroduce the aircraft, and, once the presence of the gap for reintroducing the aircraft has been determined, another fundamental aspect consists of determining the change in position of the gap in the descent path to runway for determining a reintroduction manoeuvre which leads the aircraft that missed the landing to the future position of said gap.

IPC Classes  ?

• G08G 5/00 - Traffic control systems for aircraft
• G08G 5/02 - Automatic landing aids, i.e. systems in which flight data of incoming planes are processed to provide landing data

Abstract

The present invention is a method for obtaining a ceramic slurry for the production of filaments for 3D FDM printing, comprising adding a polysaccharide, a glycol or an ethanolamine as a gelling agent to a suspension of ceramic material in order to produce said ceramic slurry. The invention also comprises the green body obtained from said slurry and the ceramic filament extruded from the green body.

IPC Classes  ?

• C04B 35/56 - Shaped ceramic products characterised by their composition; Ceramic compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on carbides
• B33Y 70/00 - Materials specially adapted for additive manufacturing
• C04B 35/565 - Shaped ceramic products characterised by their composition; Ceramic compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on carbides based on silicon carbide
• C04B 35/622 - Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
• C04B 35/634 - Polymers

Goods & Services

Decontamination of hazardous materials; Destruction of waste and trash; Energy production; Incineration of waste and trash; Material treatment information; Air purification; Recycling of waste and trash; Refining services; Upcycling [waste recycling]; Water treating. Water analysis; Chemical analysis; Energy auditing; Consultancy in the field of energy-saving; Technological consultancy; Provision of scientific information, advice and consultancy in relation to carbon offsetting; Engineering services; Scientific research; Research in the field of environmental protection; Chemical research; Scientific laboratory services; Technical research projects and studies; Chemistry services; Conducting technical project studies; Technical writing.

Abstract

Disclosed is a building game of magnetic blocks (1, 2, 3, 4, 5, 6, 7, 8, 9, 10), which comprises a plurality of parallelepiped blocks (1, 2, 3, 4, 5, 6, 7, 8, 9, 10), each provided with six faces, and in which three dimensions (length, width and height) are defined, wherein at least one of the faces of each block (1, 2, 3, 4, 5, 6, 7, 8, 9, 10) includes at least one magnet (11) to connect some blocks (1, 2, 3, 4, 5, 6, 7, 8, 9, 10) to others magnetically, some magnets (11) having a (+) polarity and other magnets (11) having a (-) polarity.

IPC Classes  ?

• A63F 9/34 - Games using magnetically moved or magnetically held pieces, not provided for in other subgroups of group
• A63H 33/04 - Building blocks, strips or similar building parts

Goods & Services

Mobile applications and software; Database engines; Database server; Scientific, research, navigation, surveying, photographic, cinematographic, audiovisual, optical, weighing, measuring, signalling, detecting, testing, inspecting, checking (supervision), life-saving and teaching apparatus and instruments; Apparatus and instruments for conducting, switching, transforming, accumulating, regulating or controlling the distribution or use of electricity; Apparatus and instruments for recording, transmitting, reproducing or processing sound, images or data; Recorded and downloadable media, computer software, blank digital or analogue recording and storage media; Coin-operated mechanisms; Cash registers, Calculating devices; Computers and computer peripherals; Diving suits, Divers' masks, Ear plugs for divers, Nose clips for divers and swimmers, Gloves for divers, Breathing apparatus for underwater swimming; Fire extinguishers. Education information, Information about sporting activities, Provided online via a computer database or the internet; Teaching; Training; Entertainment services; Sporting and cultural activities.

Goods & Services

Health monitoring software.

Abstract

The invention relates to a medical device (1) comprising: a blood pressure monitor (2), suitable for measuring the blood pressure of a user (10); a hand dynamometer (3), suitable for measuring a force exerted by the user (10); and processing means (4), configured to receive data from the blood pressure monitor (2) and from the hand dynamometer (3) and to display data to the user (10). The invention also relates to a data acquisition method that uses the medical device (1).

IPC Classes  ?

• A61B 5/021 - Measuring pressure in heart or blood vessels
• A61B 5/22 - Ergometry; Measuring muscular strength or the force of a muscular blow
• G16H 40/00 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices

Goods & Services

Electronic publications, downloadable; Electronic publications, downloadable; Downloadable electronic publications in the nature of magazines; Electronic publications in the field of interactive technology; Electronic publications recorded on computer media; Interactive electronic publications; Educational computer applications; Downloadable educational course materials; Computer software platforms; Audiovisual teaching apparatus. Books; Periodicals; Periodicals; Information books; Reference books; Educational books; Picture books; Educational publications; Manuals for instructional purposes; Educational equipment. Teaching; Education and instruction services; Publication of educational texts; Correspondence courses.

Abstract

A system for the diagnosis of wind turbines of a wind generator (6), comprising an unmanned aerial vehicle (UAV) intended to approach a wind turbine (4), characterised in that the unmanned aerial vehicle (UAV) (1) incorporates an acoustic sensor device configured to capture the sound waves arriving from a wind turbine (4), the acoustic sensor device being attached to the unmanned aerial vehicle (UAV) by means of a support, and where the acoustic sensor device (3) is in wireless data communication with a remote data receiver which collects data related to the sound waves.

IPC Classes  ?

• F03D 17/00 - Monitoring or testing of wind motors, e.g. diagnostics
• B64C 39/02 - Aircraft not otherwise provided for characterised by special use
• G01M 99/00 - Subject matter not provided for in other groups of this subclass
• G01M 13/028 - Acoustic or vibration analysis

Abstract

The present invention relates to an automatic, programmable, adaptive, low-cost system that allows the complete work flow of a bio-indicator system to be carried out from capture to analysis and identification of specimens of interest. In the case of diatom analysis, the system allows water quality indices to be determined. The subject matter of the invention has direct use in image analysis programmes for microscopy, analysis of medical images, forensic images, water quality monitoring systems, mobile phones, inter alia. The invention provides a system that is helpful both for experts and for end users in those tasks related to automatic taxonomic diatom identification, as well as in the calculation of biotic indices in monitoring the ecological state of rivers.

IPC Classes  ?

• G02B 21/08 - Condensers
• G06T 7/60 - Analysis of geometric attributes

Abstract

The invention relates to a device for carrying out biaxial tests on a cruciform specimen (3), wherein the cruciform specimen (3) comprises arms and a central zone, such that the device comprises a first plate (1) and a second plate (2), configured to be joined to one another, and four plates (9) configured to compress the arms of the cruciform specimen (3), said device also optionally comprising an L-shaped support (10) configured for the plates (1, 2) to be connected to said support (10) with the cruciform specimen (3) therebetween. According to the invention, the plates (1, 2) are cross-shaped and comprise a specimen supporting face (4), such that said specimen supporting faces (4) comprise a plurality of fillets with blunt edges (5) or a knurled surface with beveled peaks (6).

IPC Classes  ?

• G01N 3/04 - Chucks
• G01N 3/08 - Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces

Goods & Services

Retailing relating to carbon nanomaterials. Research and development services; Scientific and industrial research in the field of carbon nanomaterials; Technical research projects and studies in the field of carbon nanomaterials.

Abstract

A test machine (1) for determining a ball rebound height comprises an arm (2) hinged to a motorized actuator located in a housing (3), the arm (2) having a pivot point defining a circular path, the arm (2) including a fastening means provided for fixedly fastening a ball, an electronic board configured to detect an angle α defined by the arm (2) and a surface for bouncing the ball, upon which the ball is bounced, the housing (3) being movable by moving means designed to move on a surface. This machine is intended for automatically determining the height of rebound of a ball, for example a football ball on an artificial turf surface, eliminating the human factor during the performance of the test.

IPC Classes  ?

• G01N 3/30 - Investigating strength properties of solid materials by application of mechanical stress by applying a single impulsive force
• G01N 3/303 - Investigating strength properties of solid materials by application of mechanical stress by applying a single impulsive force generated only by free-falling weight
• G01N 3/40 - Investigating hardness or rebound hardness
• G01N 3/52 - Investigating hardness or rebound hardness by measuring extent of rebound of a striking body

Abstract

The present invention relates to a method for obtaining compounds derived from apocarotenoids in microorganisms and plants, for use in agricultural and pharmaceutical applications, which is an enzymatic method for obtaining apocarotenoid derivatives, specifically from crocetin and picrocrocin, which comprises a series of enzymatic reactions carried out by means of plant enzymes in a host system and other important crops.

IPC Classes  ?

• C12N 15/52 - Genes encoding for enzymes or proenzymes

Abstract

The invention relates to a method for the synthesis of 9,10-Bis(chloromethyl)anthracene, comprising the mixing of the reagents, anthracene and 1,3,5-Trioxane, a phase transfer catalyst selected from the group comprising quarternary ammonium salt and crown ether with hydrochloric acid and acetic acid.

IPC Classes  ?

• C07C 25/22 - Polycyclic aromatic halogenated hydrocarbons with condensed rings

Abstract

The invention relates to organocatalysts for producing cyclic carbonates. More specifically, the invention relates to imidazole-derived organocatalysts and to the use thereof for the production of cyclic carbonates from epoxides and carbon dioxide, carried out at a carbon dioxide pressure of 10 bar, at a temperature of 90º C, for reaction times of between 1 and 24 hours and with an organocatalyst concentration of 1 mol.-%, with high yields being produced.

IPC Classes  ?

• C07D 317/36 - Alkylene carbonates; Substituted alkylene carbonates
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides

Abstract

The present invention relates to a method for obtaining ceramic barbotine for the production of filaments for 3D-FDM printing, comprising adding a polysaccharide, a glycol or an ethanolamine as a gelling agent to a suspension of ceramic material in order to produce said ceramic barbotine. The invention also relates to a green body obtained from said barbotine and to ceramic filaments extruded from the green body.

IPC Classes  ?

• C04B 35/626 - Preparing or treating the powders individually or as batches
• B29B 15/08 - Pretreatment of the material to be shaped, not covered by groups of reinforcements or fillers
• C04B 35/622 - Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
• C04B 35/636 - Polysaccharides or derivatives thereof

Abstract

The present invention relates to a method for obtaining ceramic barbotine for the production of filaments for 3D-FDM printing, comprising adding a polysaccharide, a glycol or an ethanolamine as a gelling agent to a suspension of ceramic material in order to produce said ceramic barbotine. The invention also relates to a green body obtained from said barbotine and to ceramic filaments extruded from the green body.

IPC Classes  ?

• C04B 35/626 - Preparing or treating the powders individually or as batches
• B29B 15/08 - Pretreatment of the material to be shaped, not covered by groups of reinforcements or fillers
• C04B 35/622 - Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
• C04B 35/636 - Polysaccharides or derivatives thereof

Abstract

The invention relates to mutations of Candida albicans lacking functional copies of their PIR1 gene, preferably via deletion in all the copies thereof, as well as a method for producing same. Said mutations are attenuated strains that do not cause candidiasis symptoms, but do provide protection against same when injected into an animal prior to infection with an infectious strain. The invention comprises the use of said mutations to trigger a protective response against candidiasis, or specifically as live attenuated vaccines, in particular against disseminated candidiasis.

IPC Classes  ?

• C12N 1/15 - Fungi ; Culture media therefor modified by introduction of foreign genetic material
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

The invention relates to an electric current generating device for use in the treatment of motor disorders, sensory disorders and pain, comprising at least one amperage selector, a milliammeter and electric current output terminals. According to the invention, the current generated by the device is uninterrupted, with a frequency of between 10 and 50KHz, a pulse width of between 20 and 100 μs, and amperage of between 1 and 200 mA.

IPC Classes  ?

• A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

Abstract

The invention relates to a method, device and system for the monitoring and characterisation of a photovoltaic solar module (1), comprising: measuring an open-circuit voltage (V0) of the module (1); measuring a short-circuit current (Icc) of the module (1); measuring a voltage and current at a working point (V1,l1) of the module (1); estimating a voltage-current curve based on the open-circuit voltage measurement (V0), the short-circuit current measurement (Icc), and the voltage and current measurement at a working point (V1,l1). The device comprises: a measurement apparatus for measuring an open-circuit voltage (V0), a short-circuit current (Icc), and a voltage (V1) and current (l1) at a working point of the module (1). The monitoring system transmits the measurements to a control unit (2) which centralises the measurements of the devices and estimates voltage-current curves based on the measurements received.

IPC Classes  ?

• H02S 50/10 - Testing of PV devices, e.g. of PV modules or single PV cells

Abstract

Disclosed are a method for designing a slab track system and the slab track system (1) designed using said method, the method comprising the following steps: establishing (8) a dynamic load of a train under study, which load is to be supported by the slab track; establishing (9) a first geometry of the components of the slab track; performing (12) a compression fatigue calculation on the slab track system (1) by means of a numerical model; composing (17) a map of damage (44) from the numerical model of the concrete slab (4), the damage in each node being represented on a map; and considering (18) the design of the slab track system to be correct when the damage (44) in none of the nodes exceeds a value of 1. The invention also relates to a slab track system designed using this method.

IPC Classes  ?

• E01B 1/00 - Ballastway; Other means for supporting the sleepers or the track; Drainage of the ballastway
• E01B 2/00 - General structure of permanent way
• G01N 29/04 - Analysing solids
• G01N 29/46 - Processing the detected response signal by spectral analysis, e.g. Fourier analysis
• G06F 17/50 - Computer-aided design

Abstract

The invention relates to the use of a composition comprising lysine acetylsalicylate for the production of a drug in a form suitable for intravitreal administration, for the treatment of diabetic retinopathy.

IPC Classes  ?

• A61K 31/616 - Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
• A61P 27/02 - Ophthalmic agents

Abstract

The present invention is directed to composite material emitting white light comprising a MOF comprising a plurality of organic polydentate bridging ligands and a plurality, characterized in that said composite material comprises at least one guest dye capable of absorbing energy in a wavelength range emitted by the MOF when said MOF is excited, said at least one guest dye comprising a chromophore selected from the group consisting of a naphthoxazinium group, an-aromatic cyclobutdione group, a1-benzopyran-2-one group, xanthenylidene-dialkylammonium-group, a porphyrin group or a 4-dimethylaminostyryl group a boron‐dipyrromethene group and mixtures thereof. It also refers to its use in the emission of white light, sensors and imaging.

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

The invention relates to a structure for transition between different signal transmission lines in a printed circuit board (PCB). More specifically, the transition structure comprises: a metallised planar line built into the PCB, a multilayer line that can behave as a coaxial line, and a transition bridge between the planar line and the multilayer line. The configuration offers the following advantages: low cost, easy integration into a PCB, transmission without radiation or external interferences, low losses, and large bandwidth.

IPC Classes  ?

• H01P 3/123 - Hollow waveguides with a complex or stepped cross-section, e.g. ridged or grooved waveguides
• H01P 5/08 - Coupling devices of the waveguide type for linking lines or devices of different kinds

Abstract

The invention relates to a device for calibrating vector network analysers, implemented by means of SIC, ESIW and microstrip technologies. The calibration device of the invention is characterised in that it is a modular device comprising connection modules (5) connected to the vector analyser and to calibration modules (which can be SIC, ESIW or microstrip modules). This modular configuration allows the noises that are intrinsic to the connection to the analyser (including transfers to microstrip, SIC, etc.) to be the same in all of the calibration measurements, allowing the noises associated with each connection to be detected and/or eliminated.

IPC Classes  ?

• G01R 35/00 - Testing or calibrating of apparatus covered by the other groups of this subclass

Goods & Services

Printed matter; Bookbinding material; Photographs; Stationery; Adhesives for stationery or household purposes; Artists' materials; Paint brushes; Typewriters; Office requisites (except furniture); Instructional and teaching material (except apparatus); Plastic materials for packaging (not included in other classes); Printers' type; Printing blocks; Guide books. Education; Providing of training; Entertainment; Sporting and cultural activities.

Goods & Services

Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; Orthopedic articles; Suture materials; All the aforementioned goods are related to invasive and neurological physiotherapy. Wholesaling and retailing of medical and surgical apparatus, including via the internet; All the aforementioned services are related to invasive and neurological physiotherapy. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software; All the aforementioned services are related to invasive and neurological physiotherapy.

Abstract

The invention relates to fusion proteins comprising a fragment of the protein Spo20, the fluorescent protein ECFP and the fluorescent protein Venus or a variant thereof. The invention also relates to the nucleotide sequence comprising same, and to the use thereof for the in vitro detection and/or quantification of phosphatidic acid in cell membranes, for example, the plasma membrane or the mitochondrial membrane. The invention further relates to a screening method using the fusion proteins of the invention.

IPC Classes  ?

• C07K 14/395 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
• C07K 14/435 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
• C12N 15/62 - DNA sequences coding for fusion proteins
• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper

Abstract

The present invention consists of compositions, methods and devices for inducing, promoting and directing adherence, proliferation and migration of neural precursors and axonal and dendritic growth. It comprises electro-conductive substrates comprising of an electro-conductive polymer doped with polystyrene sulfonate-maleic acid copolymer (PSS-co-MA) forming biofunctionalized surfaces of microfibers for presenting one or several biomolecules of interest in order to control cell behaviour. These substrates may be used for neurological studies, cell cultures and pharmagological assays in vitro; as well as for being implanted in the nervous system in the form of scaffolds or electro-biological devices, so as to promote neural tissue repair or to improve communication in the electrode/neural cell interface in neuroprosthetic systems. The cellular effects are attained by the type, number or way of molecule binding to the substrate, by the physical properties thereof and geometry of scaffolds, by electric stimulation or by the combined action of these factors.

IPC Classes  ?

• G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
• A61L 27/00 - Materials for prostheses or for coating prostheses
• A61L 31/00 - Materials for other surgical articles
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means

Abstract

The present invention discloses a vaccine against infestations caused by blood-sucking arthropods, preferably ticks, mosquitoes, sand flies, red poultry mites, fleas, lice, sea lice, etc. The invention also claims protection for a peptide which is capable of inducing a protective immune response and which is cross-reactive vis-à-vis an infestation caused by blood-sucking arthropods, a polynucleotide, an expression vector, a host cell, a non-human animal, an antibody, and a drug, as well as the use of these products in medicine, preferably in recombinant DNA technologies and in immunology.

IPC Classes  ?

• C07K 14/435 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• A61K 38/17 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 33/00 - Antiparasitic agents

Abstract

The invention relates to proteins derived from the fusion protein tdTomato-Aequorin, to a composition containing said proteins, to the nucleotide sequence encoding same, to the use thereof for the detection and/or quantification in vitro of the intracellular calcium concentration, as well as to a kit containing said proteins and to the use of the kit for this purpose. The invention also relates to the method for obtaining the fusion protein of the invention. In addition, the invention relates to a screening method using the fusion proteins of the invention.

IPC Classes  ?

• C07K 19/00 - Hybrid peptides
• C07K 14/435 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
• C07K 14/415 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• G01N 21/76 - Chemiluminescence; Bioluminescence
• A61K 49/00 - Preparations for testing in vivo

Abstract

The invention relates to the use of a gene construction comprising a sequence encoding Dlk1 or the recombinant protein resulting from the expression of said gene construction for the preparation of a medicament for inhibiting angiogenesis, preferably tumoral angiogenesis. The invention also relates to the use of a product of the expression of Dlk1 or any of its fragments as a biomarker for determining angiogenesis or the progression thereof. The invention further relates to a method for determining pathological angiogenesis or the progression thereof, and to the use of a kit comprising the sequence encoding for dlk1 or any of its expression products for the diagnosis of pathological angiogenesis.

IPC Classes  ?

• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
• A61K 38/18 - Growth factors; Growth regulators
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
• A61P 35/04 - Antineoplastic agents specific for metastasis

Abstract

The invention relates to a water supply system comprising a tap, a cold water pipe (2), a hot water pipe, a heater (4) and a pump (5) for increasing the pressure of the water in at least one segment of the hot water pipe (3) to a level above the pressure of the water in the cold water pipe. In addition, the system includes an electronic unit (20) associated with the tap and configured to communicate with the pump (5), such that the pump can be controlled remotely from the tap by means of the electronic unit (20).

IPC Classes  ?

• F24D 17/00 - Domestic hot-water supply systems
• E03C 1/04 - Water-basin installations specially adapted to wash-basins or baths

Abstract

The invention relates to novel non-viral vectors comprising carbon nanostructures having, on the surface thereof, dendrons and/or dendrimers that are, in turn, linked to at least one biologically active molecule, for the use thereof in gene therapy and the use thereof for producing a medicament. The invention also relates to a method for the synthesis of said non-viral vectors.

IPC Classes  ?

• A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

The invention relates to a type of peritoneal dialysis solution that includes aliskiren or any of the derivatives thereof, at least one electrolyte, at least one buffer solution and at least one osmotic agent. The invention reduces the toxicity of usual peritoneal dialysis solutions in relation to peritoneal mesothelial cells. The invention also relates to the use of said type of solution in processes requiring peritoneal dialysis, such as in the case of chronic renal failure.

IPC Classes  ?

• A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
• A61M 1/28 - Peritoneal dialysis
• C07C 237/22 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Abstract

The invention relates to novel compounds having general formula (I), (II) and (III) for use in gene therapy as non-viral vehicles and to the use thereof for the development of a drug. The invention also relates to the method for the synthesis of said compounds having general formula (I), (II) and (III).

IPC Classes  ?

• C07C 237/10 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
• C12N 15/63 - Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 35/00 - Antineoplastic agents

Abstract

The invention relates to novel compounds having general formula (I) and (II) for use in gene therapy as non-viral vehicles and to the use thereof for the development of a drug. The invention also relates to the method for the synthesis of said compounds having general formula (I) and (II).

IPC Classes  ?

• C07C 237/10 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
• C12N 15/63 - Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 35/00 - Antineoplastic agents

Abstract

The invention relates to a type of solution for peritoneal dialysis, comprising Aliskiren or one of the derivatives thereof, at least one electrolyte, at least one buffer solution, and at least one osmotic agent. The invention reduces the toxicity of commonly used peritoneal dialysis solutions on mesothelial peritoneal cells. The invention also relates to the use of this type of solution for processes requiring peritoneal dialysis, such as in the case of chronic renal failure.

IPC Classes  ?

• A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
• A61K 33/06 - Aluminium, calcium or magnesium; Compounds thereof
• A61K 33/14 - Alkali metal chlorides; Alkaline earth metal chlorides
• A61P 7/08 - Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61P 17/18 - Antioxidants, e.g. antiradicals

Abstract

The present invention relates to novel triterpenic saponins from the saffron (Crocus sativus L.) corm, a composition that comprises said saponins, the use thereof as adjuvant substances in protein vaccines, and also in the production of drugs, preferably for treating cancer and, more preferably, for treating cervical carcinoma, and to a method for obtaining said saponins. The use of these triterpenic saponins as vaccine adjuvants gives rise to an enhanced, functional and long-lasting immune response to the antigen, which is greater than that of other substances with immunopotentiating capacity, such as aluminium salts, IFA (Incomplete Freund's Incomplete Adjuvant), CpG (short cytosine, phosphate and guanine bacterial DNA sequences) and even other saponins such as QuilA, without the side effects that are customarily observed when these other adjuvants are administered.

IPC Classes  ?

• C07H 15/256 - Polyterpene radicals
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
• A61P 35/00 - Antineoplastic agents
• A61P 37/00 - Drugs for immunological or allergic disorders

Abstract

Method for producing ewes' milk cheese with saffron, which comprises the steps of receiving and pre-treating the milk intended for the cheese, then curdling, moulding, pressing, sorting and maturing of the cheese, in which, prior to curdling of the milk, there is a saffron-extraction step in which ground saffron is added and mixed with a volume of milk in order to obtain a saffron extract in milk. Ewes' milk cheese with saffron obtained by means of said method, which has a fat/dry extract ratio > 0.3.

IPC Classes  ?

• A23C 19/05 - Treating milk before coagulation; Separating whey from curd
• A23L 1/221 - Natural spices, flavouring agents, or condiments; Extracts thereof

Abstract

Anaplasma marginale.

IPC Classes  ?

• A61K 39/02 - Bacterial antigens
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C07K 19/00 - Hybrid peptides
• A61P 37/04 - Immunostimulants
• A61P 33/00 - Antiparasitic agents

Abstract

The invention relates to a traffic control and regulation system based on radio frequency identification (RFID), which allows the integration and optimisation of different services governing regulated vehicle (2) parking, traffic circulation in restricted access areas, and urban and interurban tolls. Said system comprises: at least one active RFID tag (1) which is intended to be disposed inside a vehicle (2) and which contains personal information unique to each vehicle (2), identifying the owner and contracted parking and/or circulation services, whereby said tag can be used to manage the activation of said services; a radio frequency reader (4) designed to read and receive the information contained in the active RFID tags (1); and an electronic device (5) designed to recompile the information received by the radio frequency reader (4) and to detect the activation or deactivation of each of the active RFID tags (1) read by the radio frequency reader (4).

IPC Classes  ?

• G07B 15/02 - Arrangements or apparatus for collecting fares, tolls or entrance fees at one or more control points taking into account a variable factor such as distance or time, e.g. for passenger transport, parking systems or car rental systems
• G07C 1/30 - Parking meters
• G07C 5/08 - Registering or indicating performance data other than driving, working, idle, or waiting time, with or without registering driving, working, idle, or waiting time
• G06K 19/07 - Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards with integrated circuit chips

Abstract

The invention relates to a method for producing footwear with a controlled internal temperature, comprising the application of microcapsules containing phase change materials to footwear components, such as middle soles, soles, insoles or lining, and the application of a preferably aqueous adhesive. For components such as soles, insoles and middle soles, the microcapsules are applied first, followed by the adhesive. In the case of a lining component, a mixture of the adhesive and the microcapsules is applied. In both cases, the adhesive is applied using an air gun, with pressures of 0.5 to 10 bar, preferably 0.5 to 2 bar. A footwear item is obtained, such as a shoe or a boot, with components that provide thermal comfort while maintaining the internal temperature at around 32º C.

IPC Classes  ?

• A43B 7/34 - Footwear with health or hygienic arrangements with protection against heat or cold

Abstract

Electronic device for switching on a fluorescent lamp and fluorescent lamp which comprises said device, wherein said fluorescent lamp comprises a fluorescent tube (1) which has an electrical terminal (2) at each end, and wherein said fluorescent lamp is connected in parallel with an electronic module (3) and a voltage source configured to supply said fluorescent lamp, said electronic module (3) being configured to switch on a fused fluorescent lamp and keeping the latter switched on until the end of the useful life thereof as the luminous intensity thereof is reduced.

IPC Classes  ?

• H05B 41/00 - Circuit arrangements or apparatus for igniting or operating discharge lamps

Abstract

Device for regulating the luminous intensity in fluorescent lamps with an electromagnetic reactance and a starter, and lighting system which comprises said device, which comprises at least one fluorescent lamp comprising a fluorescent tube (1) which is operatively connected in parallel with a starter (3) and in series with an electromagnetic reactance (4); wherein the device comprises a regulator module (5) connected in series between said fluorescent lamp and a voltage source configured to supply said fluorescent lamp, said regulator module (5) being configured to regulate the luminous intensity of the fluorescent lamp by regulating the power consumption thereof.

IPC Classes  ?

• H05B 41/26 - Circuit arrangements in which the lamp is fed by power derived from dc by means of a converter, e.g. by high-voltage dc
• H05B 39/00 - Circuit arrangements or apparatus for operating incandescent light sources

Abstract

The invention relates to a system for the expression of peptides on the bacterial surface, characterised in that the conserved sequence of the MSP1a protein of Anaplasma marginale is used as the membrane-binding site.

IPC Classes  ?

• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• A01K 39/02 - Drinking appliances
• C07K 14/29 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
• C07K 14/435 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans

Abstract

The invention relates to a gas chromatography system for the direct coupling of liquid chromatography and gas chromatography or for the introduction of large sample volumes, which is configured to operate selectively in a retention mode. The inventive system includes a tube (2) having a first inlet part (21), a second inlet part (22) and a retention part (3) between said two inlet parts. The system also includes two gas delivery subsystems (6, 7) and a sample introduction conduit (101) which is connected to the first inlet part (21). The system further includes a discharge conduit (9) and a gas chromatography column (300), both of which are connected to the second inlet part (22). The invention also relates to a gas chromatography method.

IPC Classes  ?

• G01N 30/12 - Preparation by evaporation
• G01N 30/84 - Preparation of the fraction to be distributed

Abstract

The invention relates to a method for the production and purification of PEDF molecules and mutated and/or truncated versions of said molecule in a yeast expression system. The invention also relates to the protection of the PEDF molecules directly obtained and to the use of same in the preparation of pharmaceutical compositions. The method includes the following steps in which: the PEDF cDNA is obtained at least from cells of the retinal pigmented epithelium, mutant and/or truncated versions are obtained, the structures are cloned into a yeast expression vector, the yeast clones are transformed and selected, the yeast culture medium is inoculated with the clones obtained, the intact or truncated PEDF factor is induced in the yeast, the cells are eliminated from the culture by means of centrifugation, the culture medium containing the intact and/or truncated PEDF factor is changed, and said PEDF factor is purified and isolated.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
• C07K 14/81 - Protease inhibitors
• A61K 38/57 - Protease inhibitors from humans
• A61P 27/02 - Ophthalmic agents

Abstract

The invention relates to a method and system that enables a stack of images (or a series of aligned two-dimensional images) captured in a three-dimensional space to be analysed by computer in a fully automatic manner (without the results having to be corrected by the operator). For such an analysis, involving the use of stereological techniques such as those based on the dissector, said method/system combines the design of binary stacks and uses algorithms belonging to the field of image analysis in order to produce at least one other stack of two-dimensional images, from which the particles that fulfil the theoretical requirements of the stereological technique employed are selected. The resulting image stack can be used very efficiently and without bias or human errors to obtain numerous different quantitative data of interest for different fields and different uses (diagnostic, research, industrial, etc.).

IPC Classes  ?

• G06T 11/00 - 2D [Two Dimensional] image generation
• G06T 5/00 - Image enhancement or restoration
• G06T 5/30 - Erosion or dilatation, e.g. thinning
• G06T 5/50 - Image enhancement or restoration by the use of more than one image, e.g. averaging, subtraction

Abstract

a).

IPC Classes  ?

• B01D 15/08 - Selective adsorption, e.g. chromatography
• B01D 53/14 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• B01D 53/02 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography

Abstract

The invention describes a method for obtaining a novel freeze-dried, stable extract enriched with thiosulphonates, polysulphides, prostaglandin E1, vitamin E, inulin and ajoeno, obtained from a plant material taken from a plant of the Allium genus, the method involving conditioning, extraction, filtration, vacuum distillation and freeze-drying. The invention also concerns pharmaceutical and nutraceutical compositions containing the extract and the therapeutic uses thereof.

IPC Classes  ?

• A61K 36/8962 - Allium, e.g. garden onion, leek, garlic or chives
• A61P 7/02 - Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
• A61P 9/12 - Antihypertensives
• A61P 31/04 - Antibacterial agents

Abstract

The invention relates to a method for analysing, viewing and processing digital biomedical images, in which: at least one digital biomedical image in a first size Igi is stored in a remote server (20, 21); the biomedical image is rescaled to a second size image Im (1); an initial value is established in order to associate the second size image Im (1) with a third size image Iv (4) for the initial execution of the method; a fragment (2) to be viewed is selected from the second size image Im or the third size image Iv, said fragment being determined by initial (xi, yi) and final (xf, yf) coordinates; a magnification (3) is selected for said fragment; a request containing at least the initial and final coordinates and the magnification for the second size image Im (1) or the third size image Iv (4) is sent to the remote server; a fragment of the first size image Ig, corresponding to said initial and final coordinates and magnification, is recovered by means of rescaling and the fragment is viewed on the third size image Iv.

IPC Classes  ?

• G06T 5/00 - Image enhancement or restoration
• G06F 17/00 - Digital computing or data processing equipment or methods, specially adapted for specific functions
• G06T 11/00 - 2D [Two Dimensional] image generation

Abstract

The invention relates to automatic person recognition based on cross-comparisons of an image of an individual's right and left hands. The invention comprises a five-step process consisting of: a first step in which two cameras are used to take images of outstretched hands placed apart from one another on a suitable platform; a second step in which the images are processed and a reference system is defined for each hand; a third step in which a series of robust descrptors is established, said descriptors being determined by a set of invariant characteristics relating to both hands; a fourth step in which the individual is checked and identified using a data bank containing multiple templates of each user's two hands; and a fifth step in which output information and signals are produced. The invention is ready for immediate industrial application in fields involving access and attendance monitoring, which require persons to be checked or identified with short response times.

IPC Classes  ?

• G07C 9/00 - Individual registration on entry or exit

Abstract

The invention relates to a process for microencapsulation of phase change materials based on free radicals polymerization comprising: a) the preparation of i) a solution with, at least, a hydrophilic liquid and a stabilizer (continuous phase) and ii) a solution with, at least, a phase change material, a free radical initiator and a polymerizable material (discontinuous phase); b) the preparation of an emulsion by dispersing the discontinuous phase in the continuous phase under vigorous stirring; and c) the polymerization of monomers until the phase change material becomes microencapsulated. This process is simple and effective and avoids the use of hazardous compounds. The invention also relates to microcapsules obtainable by said process and to the use thereof in the thermal protection and storage of heat.

IPC Classes  ?

• C08F 2/24 - Emulsion polymerisation with the aid of emulsifying agents
• F28D 20/02 - Heat storage plants or apparatus in general; Regenerative heat-exchange apparatus not covered by groups or using latent heat
• B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
• C09K 5/00 - Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion

Abstract

Use of the PEDF factor to induce cell regeneration. The present invention refers to the use of the molecule PEDF for the manufacture of medicines to activate processes included in the group of regenerative processes, such as skin regeneration, wound healing, cell therapy for cardiac, neural, or hematopoietic regeneration. It also refers to the manufacture/use of pharmaceutical compounds that contain an efficient quantity of the PEDF factor for stem cell self-renewal.

IPC Classes  ?

• A61K 38/18 - Growth factors; Growth regulators
• A61P 35/00 - Antineoplastic agents
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

The invention relates to a gas chromatography system for the direct coupling of liquid chromatography and gas chromatography or for the introduction of large sample volumes, which is configured to operate selectively in a retention mode. The inventive system includes a tube (2) having a first inlet part (21), a second inlet part (22) and a retention part (3) between said two inlet parts. The system also includes two gas delivery subsystems (6, 7) and a sample introduction conduit (101) which is connected to the first inlet part (21). The system further includes a discharge conduit (9) and a gas chromatography column (300), both of which are connected to the second inlet part (22). The invention also relates to a gas chromatography method.

IPC Classes  ?

• G01N 30/12 - Preparation by evaporation

Abstract

The invention relates to a method for the analysis of pesticide residues in plants. The inventive method uses the interface device for the direct coupling of liquid chromatography and gas chromatography, known in scientific literature as TOTAD interface (Through Oven Transfer Adsorption Desorption). The method simply requires an extraction step prior to the chromatographic analysis. The pesticides are extracted from the sample with an organic solvent. Volumes of extract, which are much greater than those normally used, are injected directly into the gas chromatography, without requiring any prior extract concentration or cleaning step. The TOTAD interface enables the injection of volumes of extract that are much greater than those normally injected into the gas chromatography.

IPC Classes  ?

• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups

Abstract

The invention relates to an interphase injector device for the direct coupling of liquid chromatography and gas chromatography. The inventive device consists of: an outer body (1) comprising an inner cavity with two internal chambers (2a, 2b) which are separated by a divider element (9, 11a); a first passage (3) which extends from the first chamber (2a) to a waste product conduit (8); and an inner tube (5) which is disposed in the inner cavity and which extends through the divider element (9, 11a). The aforementioned inner tube is equipped with: a first segment (5a) in the first inner chamber (2a); a second segment (5b) in the second inner chamber (2b); an inner channel (5f) which can house an adsorbent material (6) and at least one inorganic wool material (7) which is retained inside the first segment (5a) of the inner tube by retaining means (7); and a first opening (10) which is communicated with the waste product conduit (8) solely by means of the first inner chamber (2a).

IPC Classes  ?

• G01N 30/46 - Flow patterns using more than one column
• B01D 15/08 - Selective adsorption, e.g. chromatography

Goods & Services

Scientific, nautical, surveying, electric, photographic, cinematographic, optical, weighing, measuring, signalling (warning lights), checking (supervision), life-saving and teaching apparatus and instruments; apparatus for recording, transmission or reproduction of sound or images; magnetic data-carriers, recording discs; automatic vending machines and mechanisms for coin-operated apparatus; cash registers, calculating machines, data processing equipment and computers; fire-extinguishing apparatus. Catalogues, printed matter, prospectuses, magazines and printed publications; paper, cardboard and goods made from these materials, not included in other classes; printed matter; bookbinding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); playing cards; printers' type; printing blocks. Communication. Educational services; training; entertainment; arranging of sporting and cultural activities; organisation of exhibitions for cultural or educational purposes; production of audiovisual recordings; publication of books and texts; arranging and conducting of competitions, colloquiums, conferences and congresses; providing museum facilities (presentation, exhibitions); production and presentation of live performances. The provision of accommodation, boarding and meals; services provided by establishments offering essentially food or drinks prepared for consumption; personal services provided by establishments aiming to satisfy individual needs; services provided by people, individually or collectively, in the name of members of an association, requiring a high level of mental activity; services provided by engineers dealing with appraisals, valuations, research and surveys; veterinary and agricultural services; legal services; scientific and industrial research; computer programming; providing facilities for trade fairs and exhibitions; services provided by an association for its own members.

Goods & Services

Scientific, nautical, surveying, electric, photographic, cinematographic, optical, weighing, measuring, signalling (warning lights), checking (supervision), life-saving and teaching apparatus and instruments; apparatus for recording, transmission or reproduction of sound or images; magnetic data-carriers, recording discs; automatic vending machines and mechanisms for coin-operated apparatus; cash registers, calculating machines, data processing equipment and computers; fire-extinguishing apparatus. Catalogues, printed matter, prospectuses, magazines and printed publications; paper, cardboard and goods made from these materials, not included in other classes; printed matter; bookbinding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); playing cards; printers' type; printing blocks. Communication. Educational services; training; entertainment; arranging of sporting and cultural activities; organisation of exhibitions for cultural or educational purposes; production of audiovisual recordings; publication of books and texts; arranging and conducting of competitions, colloquiums, conferences and congresses; providing museum facilities (presentation, exhibitions); production and presentation of live performances. The provision of accommodation, boarding and meals; services provided by establishments offering essentially food or drinks prepared for consumption; personal services provided by establishments aiming to satisfy individual needs; services provided by people, individually or collectively, in the name of members of an association, requiring a high level of mental activity; services provided by engineers dealing with appraisals, valuations, research and surveys; veterinary and agricultural services; legal services; scientific and industrial research; computer programming; providing facilities for trade fairs and exhibitions; services provided by an association for its own members.

Goods & Services

Scientific, nautical, surveying, electric, photographic, cinematographic, optical, weighing, measuring, signalling (warning lights), checking (supervision), life-saving and teaching apparatus and instruments; apparatus for recording, transmission or reproduction of sound or images; magnetic data-carriers, recording discs; automatic vending machines and mechanisms for coin-operated apparatus; cash registers, calculating machines, data processing equipment and computers; fire-extinguishing apparatus. Catalogues, printed matter, prospectuses, magazines and printed publications; paper, cardboard and goods made from these materials, not included in other classes; printed matter; bookbinding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); playing cards; printers' type; printing blocks. Communication. Educational services; training; entertainment; arranging of sporting and cultural activities; organisation of exhibitions for cultural or educational purposes; production of audiovisual recordings; publication of books and texts; arranging and conducting of competitions, colloquiums, conferences and congresses; providing museum facilities (presentation, exhibitions); production and presentation of live performances. The provision of accommodation, boarding and meals; services provided by establishments offering essentially food or drinks prepared for consumption; personal services provided by establishments aiming to satisfy individual needs; services provided by people, individually or collectively, in the name of members of an association, requiring a high level of mental activity; services provided by engineers dealing with appraisals, valuations and scientific and industrial research; computer programming; providing facilities for trade fairs and exhibitions; services provided by an association for its own members.

Goods & Services

Paper, cardboard and goods made from these materials, not included in other classes; printed matter, pamphlets, catalogues, magazines, books and printed publications; printed matter; bookbinding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); plastic materials for packaging (not included in other classes); playing cards; printers' type; printing blocks. Providing of education and entertainment; arranging of conferences, competitions and congresses; publication of books and texts.

Goods & Services

Paper, cardboard and goods made from these materials, not included in other classes; printed matter, pamphlets, catalogues, magazines, books and printed publications; printed matter; bookbinding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); plastic materials for packaging (not included in other classes); playing cards; printers' type; printing blocks. Providing of education and entertainment; arranging of conferences, competitions and congresses; publication of books and texts.