This invention provides isolated human antibodies and recombinant proteins comprising defined heavy chains and light chains, wherein the antibodies and recombinant proteins neutralize Andes Virus with defined IC50 values. This invention also provides related pharmaceutical compositions, treatment methods and kits.
The invention relates to a process for extracting extracellular polymeric substances (EPS) from sewage sludge from wastewater treatment plants, which comprises: (a) carrying out alkaline extraction; (b) obtaining EPS extract and stabilised sludge; and (c) purifying the EPS extract.
Levilactobacillus brevisLigilactobacillus salivariusin vitroAcinetobacter baumanniiKlebsiella pneumoniaeKlebsiella pneumoniae. The use of the probiotic formulation is intended for use as an antibiotic replacement alternative or as an adjuvant for currently used treatments.
The invention discloses a repellent and/or scented microencapsulated formulation for the agroforestry and timber industry, where said formulation is a long-acting dry or emulsified product comprising at least the following components: 1-20% m/m of eucalyptol, present in E. globulus essential oil (EEO), as an active ingredient; 5-30% m/m of a mixture of glycosidic polymers (POL); 0.5-10% of a fixer; and distilled water q.s. The invention also discloses a method for producing the formulation and its use for controlling insects, mites and other organisms, particularly species of the Scolytidae family. The formulation is applied by spraying after the anti-spot bath of the export timber, which increases the durability of the repellent action and ensures the persistence time of the product due to the use of an encapsulating polymer and a fixer as adjuvants.
The present invention relates to super austenitic stainless steels with high mechanical properties and resistance to high temperatures - sea salt for solar thermal plants with thermal energy storage. The stainless steels comprise the following components, where all the ranges are considered in percentage by weight: Cr 23-28; Ni 17-20; Mo 1-3; Mn 0.001-2; Cu 0.5-1; N 0.1-0.3; Si 0.4-0.8; C 0.05-0.12; Nb 0.05-0.5; Va 0.05-0.5; Ti 0.01-0.1; Ce 0.001-0.1; P and S less than or equal to 0.02%. The present invention further relates to the preparation process of the steels.
The present invention relates to a system for identifying pelagic species outside the water that comprises (a) an illumination system that illuminates one or more pelagic species to be analysed with controlled light; (b) an optical filter set for selecting spectral bands; (c) an arrangement of cameras with one or more wavelength ranges that record broadband or narrowband images of the illuminated pelagic species by means of optical filters; (d) an analysis unit connected to a database of pelagic species, wherein said unit comprises at least one processor configured to receive the images, compare spectral and morphological particularities that distinguish the illuminated pelagic species with records available in the database, and identify the illuminated pelagic species according to similarity criteria with the records available in the database of pelagic species. The invention further relates to a method for identifying species.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN (Chile)
Inventor
Saavedra Mondaca, Gabriel Alejandro
Moreira Lima, Gustavo De Aquino
Walborn, Stephen Patrick
Cariñe Catrileo, Jaime Andrés
Abstract
The present invention relates to a device and method for the high-speed switching of a signal that propagates from a core N in a first multi-core fibre to a core M in a second multi-core fibre, said invention comprising: a spatial mode division module, for dividing the input signal(s) into multiple spatial modes confined in the same multi-core fibre, and at the output thereof, each spatial mode has a copy of the signal(s) to be switched; a spatial mode combination module, for combining all the copies of signals that propagate in the device and carrying out interference between them; and a phase modulation module, for applying specific phases to each of the spatial modes, manipulating the interference effect between the spatial modes in the spatial mode combination module, and determining the output port of the signal to be switched.
G02B 6/35 - Optical coupling means having switching means
G02F 1/125 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on acousto-optical elements, e.g. using variable diffraction by sound or like mechanical waves in an optical waveguide structure
C12N 15/75 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
9.
METHOD FOR PRODUCING GRAPHENE-BASED MATERIALS AND USE THEREOF IN THE MANUFACTURE OF ELECTRODES FOR ELECTROCHEMICAL CAPACITORS
The present invention relates to a method for producing a graphene-based material useful for storing electrical energy for the incorporation thereof into electrochemical capacitors. The method comprises the synthesis of the graphene-based material that comprises 5 sub-steps: feeding, activation/exfoliation, micro-nano separation, nano-decanting and nano-extraction. After this graphene-based material has been obtained, the electrode is manufactured in a process which is made up of 4 sub-steps: mixing, film preparation, filling with the electrolyte, and electrode cutting process. In light of the fact that the reported results regarding the manufactured electrodes show better electrochemical performance than those disclosed in the prior art, it can be concluded that the technological solution presented, which proposes the use of graphene-based materials produced from forestry waste, is a low-cost and eco-friendly solution for use thereof in the construction of electrodes for electrochemical capacitors.
The presented invention relates to a method and device for the quantum generation of random numbers. The invention can be implemented in generation of random numbers in lotteries and gaming. The device for a self-testing quantum number generator especially in lotteries and gaming comprising: interferometer, a control unit CU connected to the signal source S, the signal is with interference property, components A that modify the signal's properties, and detectors D for measuring the signal's intensity by electrical wires. Components A are controlled by the control unit CU via electrical wires with parameters x. Detectors D are configured to measure signal intensity and send the measurement results d, via electrical wires to the control unit CU. The control unit CU performs a self-test based on the measurement results d and returns its outcome Hmin. The control unit CU returns random numbers d, and the result of self-test Hmin.
222 doped with carbon (having an atomic ratio equal to 99:1) is dispersed in a mixture of terpineol and ethyl cellulose having a percentage ratio of 94:6 in excess acetone, constantly stirring for 48 – 72 hours; subsequently, once the layer of hybrid material is deposited on the tin oxide-based electrode doped with fluorine, the acetone is left to evaporate, and it is sintered to remove the terpineol and ethyl cellulose.
H01L 31/0288 - Inorganic materials including, apart from doping material or other impurities, only elements of Group IV of the Periodic System characterised by the doping material
H01L 31/0352 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their shape or by the shapes, relative sizes or disposition of the semiconductor regions
H01L 31/18 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof
The present invention relates to an integrated bioprocess for the mixotrophic induction of astaxanthin (ATX) accumulation in Haematococcus lacustris, comprising, at least, the following steps: autotrophic culture growth under standard conditions; mixotrophic induction of ATX accumulation in photobioreactor; biomass harvesting and drying under standard conditions; and ATX extraction under standard conditions. The use of this integrated bioprocess enables cultivation without sanitary, seasonal, climatic or geographical constraints.
C12N 1/12 - Unicellular algaeCulture media therefor
C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
13.
A SYNERGISTIC BACTERICIDE AND BACTERIOSTATIC ORGANIC SANITIZING/DISINFECTANT/CLEANING FORMULATION
A synergistic bactericide and bacteriostatic organic sanitizing/disinfectant/cleaning formulation of acetic acid and propionic acid or salts thereof, having a ratio acetate (A): propionate (P) from 4:100 to 20:1, dissolved in water and diluted as required, to a final concentration in the range of 0.5% w/v to 50% w/v of the mixture in the formulation. Particularly, the present formulation comprising 0.03-15% w/v of acetate buffer and 0.04-17.50% w/v and a q.s.p filtered drinking water, pH 5-6 to be used to the food industry as a Generally Recognized as Safe Compound (GRAS), and having a significantly increased sanitizing and sterilization effect on food as well inert hard, semi-hard and soft surfaces, being safe, environmentally friendly, of broad-spectrum and high efficiency. Such foods can be selected from harvested or fresh fruits and vegetables. Such hard surfaces can be selected from domestic surfaces including floors and furniture, industrial surfaces; and hospital surfaces including medical or dental tools and equipment surfaces. It is useful to combating and/or eliminating microorganisms selected from Listeria monocytogenes, Salmonella enterica, Escherichia coli, Staphylococcus aureus, Botrytis cinerea, Pseudomonas aeruginosa, Pseudomonas syringae, Klebsiella pneumoniae, Bacillus cereus, Bacillus subtilis as well other pathogenic microorganisms or its biofilms. It can be also used as antimicrobial additive.
Composition with antiviral activity comprising water-soluble extracts of Durvillaea antarctica substantially free of alginates and a carrier or vehicle, and the method of obtaining it. Where this composition serves to prepare an antiviral drug of topical application, to prevent or treat skin or oral lesions caused by herpes viruses of the subfamily Alphahehrpesvirinae, such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) and varicella zoster virus (VZV), resistant or not to acyclovir (ACV).
ττ ττ τ and 0.5% w/v chitosan; and a dehydrated hydrogel base comprising 8% w/v starch. The present invention also relates to a method for preparing said pharmaceutical form.
A method for producing copper metal from copper concentrates without generating waste by: (a) oxidizing copper concentrate; (b) cleaning and cooling the gases; (c) feeding to a reduction reactor; (d) cleaning the gases; (e) discharging hot powders and calcines into water; (f) performing magnetic separation; (g) thickening and filtering the magnetic fraction; (h) floating silica and inert materials; (i) thickening and filtering the silica and inert materials; (j) thickening and filtering the final concentrate containing the copper metal and noble metals; (k) smelting the final concentrate of copper and noble metals; and (l) recirculating ground smelt slag to a roasting reactor.
C22B 1/26 - Cooling of roasted, sintered, or agglomerated ores
C22B 3/14 - Extraction of metal compounds from ores or concentrates by wet processes by leaching in inorganic alkaline solutions containing ammonia or ammonium salts
CENTRO DE INVESTIGACION DE POLIMEROS AVANZADOS (Chile)
Inventor
Rodriguez Llamazares, Saddys María
Sabando Correa, Constanza
Ide, Walther
Bastias Ibarra, Richard Mauricio
Abstract
An aqueous formulation that reduces the damage caused by spring frosts in plants having: (a) 0.001-2% by weight PVA micro/nanoparticles having a molecular weight of 10,000-100,000 g/mol and 1-20% acetate groups; (b) 0.0001-0.4% by weight stabilising agents; (c) 0.0005-0.05% by weight category IV adjuvants; (d) 0.00025-4% by weight emulsifier; (e) 0.003-6% by weight sodium hydroxide; and (f) 0.0065-13% by weight hydrochloric acid at 37% weight/weight and 1.18 g/mL density; a process for producing the aqueous formulation, and to uses.
This invention provides isolated human antibodies and recombinant proteins comprising defined heavy chains and light chains, wherein the antibodies and recombinant proteins neutralize Andes Virus with defined IC50 values. This invention also provides related pharmaceutical compositions, treatment methods and kits.
Lophosoria quadripinnataLophosoria quadripinnataLophosoria quadripinnata extract is at a concentration of 1.5 µg/mL, from a stock of 10 mg/mL dissolved in 50% DMSO. This graftable device stimulates bone repair and naturally induces vascularisation at the implantation site.
A flame-retardant/intumescent paint scheme useful for fire protection of wood and metal surfaces comprising two layers for foam generation and a carbonaceous layer through the addition of high molecular weight tannins. Wherein the layers of the paint scheme comprise: (A) Main components: straight-chain polyol; high molecular weight tannin; catalytic acid; and a blowing or foaming agent; and (B) Supplementary components: inorganic pigment; kaolin calcine-type pigment; alumina fillers; a binding agent; and a polymeric dispersant. In addition to the process of creating the paint scheme.
B32B 33/00 - Layered products characterised by particular properties or particular surface features, e.g. particular surface coatingsLayered products designed for particular purposes not covered by another single class
22.
METHOD FOR QUANTUM GENERATION OF RANDOM NUMBERS ESPECIALLY IN LOTTERIES AND GAMING AND DEVICE FOR QUANTUM GENERATION OF RANDOM NUMBERS
G06F 7/58 - Random or pseudo-random number generators
23.
PROBIOTIC COMPOSITION WITH BIOCONTROLLER BIOSTIMULANT EFFECT FOR AGRICULTURAL USE, WHICH COMPRISES TWO STRAINS OF WEISSELLA CONFUSA BACTERIA; PRODUCTION METHOD; FORMULATION CONTAINING SAME; AND USE OF SAME
The invention provides a probiotic composition comprising two Weissella confusa lactic acid microorganisms in a high concentration, for use in agriculture and related industries. In a preferred embodiment of the invention, a dehydrated formulation is provided, which can be applied during the process of sowing, coating or treating tubers and seeds, or can be suspended in water and sprinkled during the development of the plant. The composition of the invention allows potato crops to be protected against colonisation and infestation by the fungus P. infestans (control of late potato blight), stimulates plant development, improving yield indicators, and strengthens the properties of soil, improving its composition of beneficial microbes.
Disclosed is an air filter comprising copper-based magnetic alloys, which is useful for reducing microorganisms suspended inside hospital facilities and other enclosed spaces with a high microbial load density. The air filter comprises porous plates of copper-based magnetic alloys of the type Cu-Co-Fe, wherein the alloying agents Co and Fe are present in an amount of 5-10% w/w Co and 5-10% w/w/ Fe, or of the type Cu-SmCo5, wherein the alloying agent SmCo5 is 10-15% w/w. Also disclosed is a production method comprising the steps of: obtaining the magnetic alloys by means of mechanical grinding; compacting the porous plates of copper alloys; and preforming by compaction of the porous plates.
B22F 5/10 - Manufacture of workpieces or articles from metallic powder characterised by the special shape of the product of articles with cavities or holes, not otherwise provided for in the preceding subgroups
A synergistic bactericide and bacteriostatic organic sanitizing/disinfectant/cleaning formulation of acetic acid and propionic acid or salts thereof, having a ratio acetate (A): propionate (P) from 4:100 to 20:1, dissolved in water and diluted as required, to a final concentration i the range of 0.5% w/v to 50% w/v of the mixture in the formulation. Particularly, the present formulation comprising 0.03-15% w/v of acetate buffer and 0.04-17.50% w/v and a q.s.p filtered drinking water, pH 5-6 to be used to the food industry as a Generally Recognized as Safe Compound (GRAS), and having a significantly increased sanitizing and sterilization effect on food as well inert hard, semi-hard and soft surfaces, being safe, environmentally friendly, of broad-spectrum and high efficiency.
A composition with antiviral activity which comprises water-soluble extracts of Macrocystis pyrifera substantially alginate-free and a carrier or vehicle, and method for obtaining same. Wherein this composition serves to prepare a topical antiviral medicinal product for preventing or treating skin or oral lesions caused by herpes viruses of the subfamily Alphahehrpesvirinae, such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) and varicella zoster virus (VZV), resistant or non-resistant to acyclovir (ACV).
Disclosed are a composition with antiviral activity comprising substantially alginate-free water-soluble extracts of Durvillaea antarctica and a carrier or vehicle, and a method for producing same. The composition is used to prepare a topical antiviral drug, for preventing or treating oral or skin lesions cause by herpes viruses of the subfamily Alphahehrpesvirinae, such as herpes simplex virus 1 (HSV-1), herpes simplex virus 2 (HSV-2) and varicella zoster virus (VZV), resistant or non-resistant to aciclovir (ACV).
A hydrometallurgical process for curing primary and secondary sulphides to improve copper recovery, which comprises: (a) crushing: the size of the mineral must be reduced to less than 5 cm; (b) agglomeration: the crushed mineral must be cured in at least one continuous agglomeration drum, adding plant raffinate and/or H2O and sulfuric acid and iron chloride until 6-10% humidity is reached in the agglomerated mineral; (c) resting: once agglomerated, the mineral must be transported to heaping, where it is left to rest between 5 and 90 days with the mineral covered or uncovered; and (d) irrigation: after resting, the heaped mineral must be irrigated with a refining solution or irrigation solution to extract the sulphated copper or in a solubilisation step.
PEDIOCOCCUS SP. AND USE THEREOF IN THE PREPARATION OF A PROBIOTIC FORMULATION FOR THE PREVENTION OF DIARRHEA CAUSED BY BACTERIAL PATHOGENS THAT AFFECT DOGS AND CATS
LactobacillusPediococcussp.sp. RGM 2609, and the use of both in the preparation of a probiotic formulation for the prevention of diarrhea caused by bacterial pathogens that affect dogs and cats. This formulation can take the form of a freeze-dried granulated powder or microcapsules which, owing to their solubility in water or other liquids, allow the probiotic strains to be used in pet food, whether liquids or jellies.
CONSUMABLE VARIABLE ELECTRODE AND FIXED ELECTRODE ARC DISCHARGE SYSTEM UNDER CONTROLLABLE ATMOSPHERE, WITH DIFFERENTIAL ELECTROSTATIC PRECIPITATOR WITH CORONA DISCHARGE, USEFUL FOR THE SYNTHESIS AND COLLECTION OF NANOMETRIC MATERIAL OF A METALLIC AND METAL OXIDE NATURE
An arc discharge system under controlled atmosphere useful for the continuous mass production of nanometric material and for the separation of products classified by size comprising at least the following zones: (a) feed; (b) reaction chamber equipped with a fixed electrode and a variable electrode for maintaining a continuous and controlled electric arc; and (c) collection chamber composed of a differential electrostatic precipitator with corona discharge.
B01J 19/08 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
32.
MULTI-POLYMER HYDROGEL AS A DEVICE FOR ADMINISTERING PHARMACEUTICAL AND CELLULAR THERAPEUTIC COMPONENTS
Disclosed is a multi-polymer hydrogel used as a medical device for administering pharmaceutical and cellular therapeutic components, which comprises at least the following components: 2-4% chitosan; 0.01-4% polyvinyl alcohol; 2-4% starch; 0.01-4% polyethylene glycol; 250-500 µL crosslinker; and 80-92% mildly acidic aqueous solution. The hydrogel allows pharmaceutical and cellular therapies to be applied in a time-controlled manner and centrally on the application site, acting as a support and protective element for the therapeutic component.
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61K 47/58 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
A61L 15/20 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
A61L 15/24 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bondsDerivatives thereof
A61L 15/26 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bondsDerivatives thereof
Venus AntiquaVenus Antiqua is disclosed, using a long-line type system. The culture system is manufactured from a high-density plastic and comprises, at least, an upper anchoring structure wherefrom the system is suspended; culture units stacked on each other and supporting the trays, and the culture trays. The latter are separated from each other by 30-60 cm; this free space enables a flow of water with nutrients; a substrate, preferably sand, must be placed in each tray, said substrate having a minimum thickness of 30 cm in order to enable the seeds to be buried.
Disclosed are strains of Lactobacillus kunkeei and Bifidobacterium asteroides and the use thereof to produce a probiotic biostimulant formulation for bees. The strains are deposited in the Chilean Collection of Microbial Genetic Resources (CChRGM) and allow the loads of two important bee pathogens, Nosema ceranae Fries (Microsporidia) and deformed wing virus (DWV), to be reduced, meaning a 63% reduction in mortality in bees in the colony that are infected with both pathogens, thus increasing the bee population in the colony by up to 160%, compared to untreated bees.
Pseudomonas protegensPseudomonas protegens, RGM 2331, capable of producing the phytohormone indole acetic acid (IAA) and solubilising phosphorus (P), these features allowing same to be used to produce a biostimulant with antifungal properties, to promote growth in plants. The biostimulant and the use thereof directly on the foliar part or on the roots are also claimed.
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
36.
METHOD FOR PRODUCING GRANULATED CONTROLLED-RELEASE COMPOUND UREA FERTILISERS USING CHITOSAN–TRIPOLYPHOSPHATE POLYMER MATRICES, AND SAID FERTILISERS
The invention relates to a method for producing granulated controlled-release compound chitosan–tripolyphosphate–urea fertilisers, which comprises at least the following steps: (a) adding components; (b) carrying out extrusion dripping and cross-linking; (c) washing microspheres; (d) incorporating urea into the microspheres; and (e) drying the fertiliser. The invention also relates to said fertilisers.
C05C 9/00 - Fertilisers containing urea or urea compounds
C05G 3/40 - Mixtures of one or more fertilisers with additives not having a specifically fertilising activity for affecting fertiliser dosage or release rateMixtures of one or more fertilisers with additives not having a specifically fertilising activity for affecting solubility
The invention relates to a method for producing copper metal from copper concentrates without generating waste, which comprises: (a) oxidizing copper concentrate; (b) cleaning and cooling the gases; (c) feeding to a reduction reactor; (d) cleaning the gases; (e) discharging hot powders and calcines into water; (f) performing magnetic separation; (g) thickening and filtering the magnetic fraction; (h) floating silica and inert materials; (i) thickening and filtering the silica and inert materials; (j) thickening and filtering the final concentrate containing the copper metal and noble metals; (k) smelting the final concentrate of copper and noble metals; and (l) recirculating ground smelt slag to a roasting reactor.
The invention relates to a method for producing copper metal from copper concentrates without generating waste, which comprises: (a) oxidising copper concentrate; (b) cleaning and cooling the gases; (c) feeding to a reduction reactor; (d) cleaning the gases; (e) discharging hot powders and calcines into water; (f) performing magnetic separation; (g) thickening and filtering the magnetic fraction; (h) floating silica and inert materials; (i) thickening and filtering the silica and inert materials; (j) thickening and filtering the final concentrate containing the copper metal and noble metals; (k) smelting the final concentrate of copper and noble metals; and (l) recirculating ground smelt slag to a roasting reactor.
The invention relates to a zero-waste process that uses final slag from copper smelting to produce commercial products, which comprises: (a) charging/pouring materials: adding a reducing agent, slag and oxides to a reactor/oven; (b) reducing iron oxides: keeping the temperature above 1550°C to begin the reactions of decomposition and reduction and, in parallel, dissolving the reducing agent in liquid Fe until obtaining pig iron; (c) forming slag: occurs alongside the step of reducing, at a bath temperature above 1450°C, and as the oxides are reduced, the pig iron phase is produced, the increase in the concentration of SiO2 allowing the fusion temperature of the slag to increase, thereby obtaining three phases, pig iron, oxides and gases; and (d) discharging the products.
CENTRO DE INVESTIGACIÓN DE POLÍMEROS AVANZADOS (Chile)
Inventor
Rodríguez Llamazares, Saddys María
Sabando Correa, Constanza
Ide, Walther
Bastías Ibarra, Richard Mauricio
Abstract
The invention relates to an aqueous formulation that reduces the damage caused by spring frosts in plants, which comprises: (a) 0.001–2% by weight PVA micro/nanoparticles having a molecular weight of 10,000–100,000 g/mol and 1–20% acetate groups; (b) 0.0001–0.4% by weight stabilising agents; (c) 0.0005–0.05% by weight category IV adjuvants; (d) 0.00025–4% by weight emulsifier; (e) 0.003–6% by weight sodium hydroxide; and (f) 0.0065–13 % by weight hydrochloric acid at 37% weight/weight and 1.18 g/mL density. The invention also relates to a process for producing the aqueous formulation, and to uses.
A process for producing lithium carbonate or other lithium chemical products from spodumene ore concentrates, LiAl(SiO3)2, which comprises: (a) calcining the spodumene concentrate to transform it from its crystalline form α to the crystalline form; (b) dehydrating hydrated ferrous sulphate; (c) sulphation reaction of the spodumene with anhydrous ferrous sulphate; (d) cooling the sulphated calcines; (e) leaching the calcines; (f) thickening and filtering the pulp generated; (g) forming lithium and aluminium sulphate; (h) thickening and filtering the pulp; (i) precipitating and filtering the pulp; (j) precipitating the lithium carbonate; (k) thickening and filtering the pulp; and (l) drying and packaging the lithium carbonate precipitate.
Helix aspersaHelix aspersa Müller deposited in the Chilean Collection of Microbial Genetic Resources (CChRGM) under access codes RGM 2678 and RGM 2679. Also described is a topical formulation containing same and the use thereof as probiotics for the prevention and adjuvant treatment of acne vulgaris.
The present invention is related to the technical field of biotechnology; more specifically, the invention relates to a method for the large-scale production of peptides of interest by expression of a concatemer that codes for a polypeptide containing tandem sequences from the peptide of interest, and the excision of said polypeptide to obtain a plurality of individual copies of said peptide of interest. The invention is particularly useful for the production of peptides with immunomodulatory and anti-inflammatory properties for use in the fish-farming industry.
The invention relates to an aerogel that allows blood absorption and clot formation for wound healing, which comprises 60-93% w/w graphene oxide noncovalently functionalised with a deacetylated chitin derivative in a proportion of 50-5% w/w and 15-2% w/w proanthocyanidins in the matrix thereof.
A61L 15/18 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
45.
HYDROTHERMAL METHOD FOR SYNTHESISING A COMPOSITE ZEOLITE MATERIAL OF CLINOPTILOLITE AND PHILLIPSITE, USEFUL FOR REMOVING ARSENIC FROM DRINKING WATER
22322222O=191, the mixture being stirred at 120-140 rpm for at least 10 minutes and maintained at 130-170°C for at least 5.5 days at autogenous pressure in a static system; (b) cooling: the composite material of clinoptilolite and phillipsite is left to cool for 6-10 hours; and (c) filtering, washing and drying: the material is filtered and washed with plenty of double-distilled water and is finally dried at 120°C for at least 15 hours. The invention also relates to the zeolite material and its use.
C01B 39/02 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereofDirect preparation thereofPreparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactantsAfter-treatment thereof
C01B 39/28 - Phillipsite or harmotome type, e.g. type B
C01B 39/46 - Other types characterised by their X-ray diffraction pattern and their defined composition
The technology corresponds to a formulation to protect against kiwi bacteriosis, caused by the bacterium Pseudomonas syringae pv. actinidiae (Psa), which comprises the biomass of the strains Pseudomona protegens ChC7 (RGM 2328) and CA2 (RGM 2329), plus excipients. This formulation enables direct protection against the pathogenic bacterium by activating defence genes present in plants and colonising their interior, reducing the systemic damage caused by Psa and enabling the generation of protection during crop growth, especially during flowering.
The invention relates to a device for correcting sleep bruxism by using a system for electrical stimulation of the mental nerve, which is portable and comprises the following components: (1) an occlusal splint containing an intrabuccal electronic neurostimulator formed by at least four capacitive pressure sensors for detecting interdental pressure, a microcontroller unit (MCU) that allows pressure signal data to be acquired and stimulation to be controlled by means of a pre-programmed algorithm, a power system for powering the microcontroller, a stimulus generator, and stimulation electrodes; and (2) an external base station comprising a power source for providing electricity to the neurostimulator by means of an inductive link and a wireless communication system with an interface on a computer for configuration and reporting.
A mineral flotation process is disclosed for increasing the recovery of molybdenite and copper sulphates, and particularly the recovery of fines, which comprises at least the following stages: (A) Primary Conditioning and Flotation; (B) Regrinding; (C) Cleaning Conditioning and Flotation; (D) Scavenger Conditioning and Flotation.
The present technology corresponds with a method for producing the recombinant protein of functional allophycocyanin, based on the use of three bicistronic vectors each including two sequences of interest, said sequences coding for different variants of the subunits necessary for producing a functional protein. The variants produced correspond with a variant of the α subunit of APC, a variant of the β subunit of APC, a variant of the S subunit of the heterodimeric lyase, a variant of the U subunit of the heterodimeric lyase, a variant of the phycocyanobilin oxidoreductase, and a variant of hemooxygenase.
The invention relates to an in-line system for detecting the quality of fruit via ultrasound, comprising a support arch positioned over the processing line in a perpendicular manner, on which two transducers are secured, a detection unit coupled to the support arch and having a piezoelectric transmitter and frequency range, directed towards the centre of the processing line a control unit formed by an analogue module for receiving waves, an A/D converter, and a microcontroller, a rotary synchronisation encoder located below the processing line, connected to the control unit of the detection unit, wherein this encoder is coupled to a discard unit for removing the fruit with detected defects from the processing line, and a wave generator connected to the control unit. The invention also relates to the use of the detection system.
G01N 29/06 - Visualisation of the interior, e.g. acoustic microscopy
G01N 29/07 - Analysing solids by measuring propagation velocity or propagation time of acoustic waves
G01N 29/11 - Analysing solids by measuring attenuation of acoustic waves
G01N 29/14 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object using acoustic emission techniques
G01N 29/34 - Generating the ultrasonic, sonic or infrasonic waves
51.
IN-LINE SPRAYING SYSTEM VIA ULTRASOUND, WHICH CAN BE USED IN THE DISPENSING OF AGROCHEMICAL AGENTS FOR POST-HARVEST FRUIT
The invention relates to an in-line spraying system via ultrasound, which can be used in the dispensing of agrochemical agents for post-harvest fruit, comprising: a spray chamber formed by a closed tank containing the liquid to be sprayed, an agitator, two ultrasound transducers and a fan; a chamber for applying the mist to the fruit, formed by a closed chamber disposed on the processing line, which has gates with slats for allowing the fruit in and out, a cylindrical applicator for the agrochemical, which is connected to the spray chamber via a duct; and a chamber for recovering the mist, formed by a closed tank coupled to the application chamber, below the processing line, which is connected to the spray chamber via a duct, and wherein the recovered mist is moved by the fan. The invention also relates to a process for operating the system.
A23L 3/30 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by irradiation without heating by treatment with ultrasonic waves
A23L 3/34 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
A23L 3/3409 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of gases, e.g. fumigation; Compositions or apparatus therefor
B05B 17/04 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
52.
POWDERED MICRO-ENCAPSULATED DOSAGE FORM COMPRISING AN EXTERNAL CORONA AND A CORE WITH NANOPARTICLES
The present technology relates to a powdered pharmaceutical dosage form with a spatial shape having a microcapsule form, which comprises an external polysaccharide-based capsule or corona; and a core containing nanoparticles of a polymer or lipid material, the nano-encapsulated active ingredient and a surfactant. The invention also relates to a method for obtaining the microcapsules and to their use.
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
53.
COMPOSITION FOR STIMULATING THE IMMUNE SYSTEM IN FISH, WHICH CONTAINS RECOMBINANT PEPTIDES; IMMUNOSTIMULANT RECOMBINANT PEPTIDES; AND NUCLEOTIDE SEQUENCES ENCODING SAME
The present invention relates to a composition, a microparticle and a food formulation comprising recombinant peptides that stimulate the immune system and increase the systemic antibacterial response in fish; to the amino acid sequences of the recombinant peptides; and to the nucleotide sequences encoding same. The invention strengthens the immune system of fish, allows infection by a wide ranges of pathogens (viruses and bacteria) to be prevented, and in addition, does not cause collateral environmental damage.
This invention provides isolated human antibodies and recombinant proteins comprising defined heavy chains and light chains, wherein the antibodies and recombinant proteins neutralize Andes Virus with defined IC50 values. This invention also provides related pharmaceutical compositions, treatment methods and kits.
The invention relates to a hydraulic ultra flocculation reactor for recovering water from fine mine tailing pulps, which comprises at least one external cylindrical casing with diameters of the base and of an upper area in a ratio of between 1:2 and 1:4; an internal casing joined to the external casing in an upper section for the inlet of the influent, configured as a cylinder joined to a cone, stacked cylinders or a spiral; and an effluent inlet duct and an influent outlet duct that are disposed tangentially to the base of the external casing, are located at opposite ends of the reactor and face the same direction, both ducts having a diameter in a ratio of between 1:12 and 1:8 in relation to the diameter of the base of the external casing.
The present invention relates to a vaccine against hantavirus pulmonary syndrome (HPS), comprising recombinant polypeptides that allow immunity to be developed against the hantaviruses that cause HPS. Said recombinant polypeptides contain a specific antigenic fragment of the Gn and GC sequence of the Andes virus. The present invention also relates to the amino acid sequences of the recombinant polypeptides and to the nucleotide sequences coding same.
Haematococcus pluvialisHaematococcus pluvialis, deposited in the Spanish Bank of Algae (SBA) under access code BEA IDA 0064B, which has a cellular volume 60% greater than the base strain, both in vegetative state and in cyst state, and also produces 30 to 40% more astaxanthin in dry weight compared to the base strain.
C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound
C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
58.
PHYTOTHERAPEUTIC POWDER FORMULATION AND USE THEREOF IN THE EVENT OF A HYPERTENSIVE CRISIS
The invention relates to a phytotherapeutic powder formulation comprising 1.0-2.5 g dried Citrus limon juice and 2.0-3.5 g polysaccharide, and to the use thereof to prepare a drug useful in the event of a hypertensive crisis and as a complement to therapies for managing increases in blood pressure, without exercising hypotensive effects, as blood pressure is not decreased in normotensive patients.
The present technology relates to a pelleted food rich in polyunsaturated fatty acids (PUFAs) for salmonid alevins, which comprises biomass of Rhodotorula sp. NCYC4007, raw protein, lipids, water, ash and raw fibre. The food provides omega-3 PUFAs such as DHA and EPA, and carotenoid pigments such as β-carotene and canthaxanthin, from the strain NCYC4007. Protection is also sought for a method for producing and using same in the early feeding of farmed fish, as this is the stage when the aquaculture industry sees the highest feeding-related mortality among individual fish.
C12P 7/64 - FatsFatty oilsEster-type waxesHigher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl groupOxidised oils or fats
Two-color net for protecting fruit against damage caused by direct solar radiation and high temperatures, used in combination and/or separately, which is made with two monofilaments that are blue and grey in color with a thickness of 0.26-0.32 mm.
A01G 13/02 - Protective coverings for plants; Devices for laying-out coverings
D04B 21/00 - Warp knitting processes for the production of fabrics or articles not dependent on the use of particular machinesFabrics or articles defined by such processes
D01F 8/04 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers
A01G 7/04 - Electric or magnetic treatment of plants for promoting growth
in vitroin vitroin vitro to determine the genetic characteristics of the embryo based on the genomic DNA content, without taking a biopsy from the embryo, which is a reliable and non-invasive method for pre-implantation genetic diagnosis, is proposed.
The present technology relates to an in-vitro cell-preconditioning process for obtaining mesenchymal stem cells (MSCs) with immunomodulatory properties, which comprises the following steps: a) obtaining MSCs from donor animal tissues (biopsies); b) transporting and processing the biopsies; c) developing cultures by incubating at 39 ºC with 5% CO2; d) determining cell viability; e) analysing MSC surface markers; f) preconditioning the previously described cells with substance P, PGE2, oxytocin and/or combinations thereof and under conditions of atmospheric oxygen tension (normoxia) and/or hypoxia; g) confirming the acquisition of an immunomodulatory phenotype; and h) using the preconditioned cells, directly in patients or frozen for future use. Protection is also sought for use of said process in allogenic therapies in humans and non-human mammals.
The invention relates to a selective dissolution method for obtaining at least one fraction of bark components, which comprises: (a) impregnating in vapour phase: a lignocellulosic material with a diameter less than 5 mm and a moisture content less than or equal to 40% is impregnated in a mass ratio between 1:1 and 1:3 with vapours of a solvent or mixture of solvents for a period less than or equal to 20 minutes and at a pressure between 1 and 12 atm; (b) dissolving: the compounds of interest are dissolved in the solvent inside the bark particles for a period less than or equal to 30 minutes, at a temperature between 20 and 200 °C and at a pressure between 1 and 12 atm; and (c) mechanical pressing: the impregnated bark is subjected to pressing for a period less than or equal to 5 minutes and at a pressure between 5 and 200 atm, to separate the liquor.
C07C 62/00 - Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings and containing any of the groups OH, O-metal, —CHO, keto, ether, groups, groups, or groups
C09K 15/34 - Anti-oxidant compositionsCompositions inhibiting chemical change containing plant or animal materials of unknown composition
66.
Process allowing the removal through digital refocusing of fixed-pattern noise in effective images formed by electromagnetic sensor arrays in a light field
A process that allows the removal of fixed-pattern noise in effective images formed by electromagnetic sensor arrays in a light field, which includes at least the following steps: (a) The formation of a digital image from an electromagnetic sensor array; (b) the formation of a light field that must have at least 2×2 digital images of a scene, with a separation distance of at least the size of the effective area of an electromagnetic sensor; and (c) the reconstruction of an image by means of digital refocusing from the light field.
This invention provides isolated human antibodies and recombinant proteins comprising defined heavy chains and light chains, wherein the antibodies and recombinant proteins neutralize Andes Virus with defined IC50 values. This invention also provides related pharmaceutical compositions, treatment methods and kits.
The invention relates to a method for obtaining a fibrous material from bark that can be used to produce insulating materials, comprising the use of Eucalyptus sp. bark in a purely mechanical cutting, shearing and/or compression process, for the processing thereof. The invention also relates to the resulting insulating material and the use thereof.
D01B 1/00 - Mechanical separation of fibres from plant material, e.g. seeds, leaves, stalks
D21B 1/02 - Pretreatment of the raw materials by physical or chemical means
D21B 1/06 - Fibrous raw materials or their mechanical treatment by dividing raw materials into small particles, e.g. fibres by dry methods
B27L 1/00 - Debarking or removing vestiges of branches from trees or logsMachines therefor
B27L 11/00 - Manufacture of wood shavings, chips, powder, or the likeTools therefor
B27N 3/00 - Manufacture of substantially flat articles, e.g. boards, from particles or fibres
B27N 3/04 - Manufacture of substantially flat articles, e.g. boards, from particles or fibres from fibres
E04B 1/74 - Heat, sound or noise insulation, absorption, or reflectionOther building methods affording favourable thermal or acoustical conditions, e.g. accumulating of heat within walls
E04B 1/76 - Heat, sound or noise insulation, absorption, or reflectionOther building methods affording favourable thermal or acoustical conditions, e.g. accumulating of heat within walls specifically with respect to heat only
E04C 2/16 - Building elements of relatively thin form for the construction of parts of buildings, e.g. sheet materials, slabs, or panels characterised by specified materials of wood, fibres, chips, vegetable stems, or the likeBuilding elements of relatively thin form for the construction of parts of buildings, e.g. sheet materials, slabs, or panels characterised by specified materials of plasticsBuilding elements of relatively thin form for the construction of parts of buildings, e.g. sheet materials, slabs, or panels characterised by specified materials of foamed products of fibres, chips, vegetable stems, or the like
69.
HYDROPHOBIC BIOCIDAL EMULSION THAT CAN BE USED TO PROTECT WOOD
The invention relates to a hydrophobic and biocidal emulsion that can be used to protect wood, said emulsion comprising at least the following components: (a) between 60 and 99 wt.-% emulsified paraffin in an aqueous medium with a total solid content greater than 45%, and (b) between 1 and 40 wt.-% lignin in solid form and/or in solution. The invention also relates to the uses thereof.
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
B05D 7/06 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to wood
B27K 3/50 - Mixtures of different organic impregnating agents
70.
BIOFILTER FOR THE TREATMENT OF WATER WITH A HIGH HEAVY METAL CONTENT, COMPRISING A BIOMASS COMPOSED OF A MIXTURE OF MACROALGAE IMMOBILISED IN A POLYMERIC MATRIX
The present technology corresponds to a biofiltering composition, a biofilter and a method for producing same, the biofilter comprising a biomass composed of a mixture of macroalgae selected from the genera Macrocystis pyrifera, Durvillaea antarctica, Lessonia spicata, Gracilaria chilensis and/or Ulva spp. and immobilised in a polymeric alginate matrix.
C02F 3/32 - Biological treatment of water, waste water, or sewage characterised by the animals or plants used, e.g. algae
C02F 101/20 - Heavy metals or heavy metal compounds
B01J 20/00 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof
71.
RECOMBINANT VACCINE AGAINST THE PORCINE CIRCOVIRUS, STRENGTHENED WITH AN IMMUNOMODULATOR
The invention relates to a recombinant vaccine against the porcine circovirus type 2, based on a chimeric variant of the protein CAP, which is strengthened with an immunomodulator, preferably porcine interferon alpha. The invention also relates to a synthetic polynucleotide sequence that encodes said protein variant, a recombinant protein of this type, a vector for the expression of genes of interest in the yeast Pichia pastoris which permits the production of the components of the vaccine, an expression cassette, a transformed yeast cell, and a method for the production of a vaccine against porcine circovirus type 2 in yeasts.
BIOACTIVE PAPER COMPRISING AS ITS BASE AN ALGAE-PAPER CONSISTING OF SECONDARY CELLULOSE FIBRES IN COMBINATION WITH BROWN ALGAE BIOMASS, AND ANTIMICROBIAL EXTRACT OBTAINED FROM BROWN ALGAE AND ADDED TO THE ALGAE-BASED PAPER
The present invention comprises a bioactive paper consisting of secondary cellulose fibres in combination with brown algae biomass, and an antimicrobial extract obtained from brown algae. The method for producing said bioactive paper and the use thereof to protect fruit and vegetables against oxidative stress from the air, bacterial attack and, mainly, phytopathogenic fungi, thereby allowing damage prevention during the storage and transport thereof, is also described.
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
D21H 11/10 - Mixtures of chemical and mechanical pulp
The invention relates to a net for protecting fruit against damage caused by direct solar radiation and high temperatures, acting together and/or independently, which is made from two monofilaments that are pearl, blue or grey in colour and have a thickness of between 0.26 – 0.32 mm.
A01G 13/02 - Protective coverings for plants; Devices for laying-out coverings
D01F 8/04 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers
D04B 21/00 - Warp knitting processes for the production of fabrics or articles not dependent on the use of particular machinesFabrics or articles defined by such processes
74.
STIMULATOR THAT ALLOWS SLEEP BRUXISM TO BE TREATED USING ELECTRICAL SIGNALS
The invention relates to a stimulator system that allows sleep bruxism to be treated using electrical signals, the system having a built-in electronic intrabuccal neurostimulator and a base station. According to the invention, the intrabuccal neurostimulator comprises: a system for receiving energy; a system for storing energy; a microprocessor for controlling stimulation according to pre-set parameters; a stimulus generator; electrodes with low corrosion levels; and packaging for protecting the stimulator. The base station comprises: a power source; a microprocessor for controlling the energy delivered wirelessly to the intrabuccal neurostimulator; a user interface; a wireless data communication circuit for communicating with the intrabuccal neurostimulator; and a wireless energy transmission system.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
75.
PROCESS THAT PERMITS THE REMOVAL OF FIXED-PATTERN NOISE IN EFFECTIVE IMAGES FORMED BY ARRANGEMENTS OF ELECTROMAGNETIC SENSORS OF A LIGHT FIELD BY MEANS OF A DIGITAL REFOCUSING
The invention relates to a process that permits the removal of fixed-pattern noise in effective images formed by arrangements of electromagnetic sensors of a light field, comprising at least the following steps: (a) forming a digital image based on an arrangement of electromagnetic sensors; (b) forming a light field, which should have at least 2 x 2 digital images of a scene, having a separation distance of at least the size of the effective area of an electromagnetic sensor; and (c) reconstructing an image by means of a digital refocusing based on the light field.
The invention relates to a nutraceutical product that modulates appetite and induces insulin sensitivity in mammals, comprising at least the following components: a) 25-60% by weight cold-pressed oil extracted from Pinus radiata seed; b) 60-25% by weight cold-pressed oil extracted from Glycine max seed; c) 0.4-20% liposoluble vitamins; d) 2-40% gelatine of plant or animal origin; e) 0.6-15% plasticisers of the polyalcohol family; and f) water q.s.
A61P 3/08 - Drugs for disorders of the metabolism for glucose homeostasis
77.
N-(BUTAN-2-YL)-2-[3-(1H-INDOL-3-YL)PROPANAMIDO]PROPANAMIDE COMPOUND THAT INTERACTS WITH THE GΒΓ PROTEIN OF THE GLYCINE RECEPTOR, WHICH CAN BE USED TO TREAT THE SYMPTOMS OF ACUTE ETHANOL INTOXICATION
The technology corresponds to molecules that inhibit ethanol-mediated potentiation that affects the glycine receptor. These molecules interact with the G beta gamma (Gβγ) protein at a molecular level in the central nervous system and as a result can be used to generate a formulation for treating acute ethanol intoxication.
The present invention relates to an antifouling bio-paint comprising a two-barrier protection system. The paint comprises extracts of macroalgae that attract epibiont bacteria, with anti-micro-fouling activity, and active extracts of bacteria with antifouling property, the extracts being immobilised in a polymer matrix. The bio-paint is used on inert surfaces exposed to seawater, principally nets for use in aquaculture, pipelines, and boat hulls.
The invention relates to a pediculicide formulation based on Eucalyptus globulus essential oil, which is effective on P. humanus capitis, provides ovicidal activity, an effect on the adhesion of the P. humanus egg, a short estimated time of death of the parasite, zero toxicity, and it is impossible for the parasite to become resistant. The formulation is formed by ethanol as a solvent, isopropanol as a vehicle, Eucalyptus globulus essential oil as the active compound, and optionally isopropyl myristate as an emollient, as well as a sufficient quantity of distilled water. The formulation is provided in the form of a hydroalcoholic lotion or as a w/o emulsion if isopropyl myristate is used.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
ELECTRO-PNEUMATIC SUBMERSION/FLOTATION UNIT FOR A REMOTELY-CONTROLLED BALLASTABLE-TYPE SINKING SYSTEM, AND METHOD FOR REMOTELY OPERATING SAID SINKING SYSTEM
PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO (Chile)
UNIVERSIDAD DE CONCEPCIÓN (Chile)
Inventor
Hurtado Ferreira, Carlos Felipe
Arenas Crisóstomo, Mauricio Victoriano
Abstract
The invention relates to an electro-pneumatic submersion/flotation unit for a remotely-controlled ballastable-type sinking system, comprising: (a) a submersion/flotation unit; (b) a marine unit arranged around the sinking system; (c) a land unit including a land base station; and (c) remote actuation and monitoring software. The invention also relates to the method for remotely operating the submersion/flotation unit.
The technology corresponds to nanoparticles based on chitosan for the transport of peptides with activity in the central nervous system, consisting of: (a) chitosan, as a base; (b) sodium triplyphosphate (TPP), as a cross-linking agent; and (c) thiamine pyrophosphate (TDP), as a signalling agent. These nanoparticles are used to produce a medicament that can be used for treating disorders of the central nervous system and can be administered intravenously or intranasally.
The invention relates to a masterbatch composition that can be used in the production of dental prostheses, comprising: a nanoscale filler formed by between 0.05 - 0.20 wt.-% silver nanowires, between 0.05 - 0.20 wt.-% copper nanowires, and between 0.08 - 2.00 wt.-% zinc oxide nanowires; and liquid components comprising between 45 - 65 ppm methyl methacrylate monomer with an inhibitor, between 0.3 - 1.0 wt.-% ethylene glycol dimethacrylate-type crosslinking agent, and traces of a N,N dimethyl-p-toluidine-type activator. The invention also relates to the production method thereof.
REACTIVE EXTRUSION PROCESS FOR THE PRODUCTION OF A BIOPLASTIC MATERIAL WITH BIOACTIVE PROPERTIES, FROM COMPOSTABLE MATERIALS FROM RENEWABLE SOURCES AND FOSSILS, AND RESULTING BIOPLASTIC MATERIAL
The invention relates to a reactive extrusion process for the production of a bioplastic material with bioactive properties, from compostable materials from renewable sources and fossils, said process comprising the following steps: (a) supplying a PLA extruder with an Ecoflex® polymer and alga, preferably of the Ulva sp. type; (b) mixing polymers and alga; (c) degasifying the fumes generated during the reactive extrusion; and pelletizing the bioplastic material. The invention also relates to the resulting bioplastic material.
The invention relates to recombinant antibody-related polypeptide molecules which specifically recognise human vascular endothelial growth factor-A (VEGF-A) and interfere with the in vivo proangiogenic and in vitro stimulatory effects thereof. These polypeptide molecules are formed by multiple sites made up of amino acids encoded by DNA sequences of variable regions of antibodies, for binding to VEFG-A. The molecules can be recombinant antibodies, single-chain antibody fragments (scFv), Fab-type antibody fragments, or multimeric molecules.
The invention relates to a method that enables the production of recombinant proteins in the milk of non-transgenic mammals. The method is based on the direct transfer of the genetic information of interest to the cells forming the secretory mammary epithelium, by means of adeno-associated vectors. Using this method, it is possible to produce high levels of recombinant proteins in the milk of non-transgenic mammals during a complete lactation period. The method is scalable and enables sustained levels of expression to be achieved for periods of more than 100 days.
This technology comprises specific sequences of interfering RNA having the capacity to negatively regulate the expression of the RNA coding for the receptor LOX-1. These sequences can be the nucleotide sequences corresponding to SEQ ID NO 1, SEQ ID NO 2, SEQ ID NO 3, SEQ ID NO 4, or SEQ ID NO 5, as well as fragments of said sequences, which maintain the capacity to negatively regulate the expression of the RNA coding for the receptor LOX-1, or homologues of these sequences. The invention also relates to the use of these nucleotide sequences in the production of medicines that permit the blocking of the growth and progression of tumour cells in the prostate in a selective, effective and specific manner, permitting the mass administration of these nucleotide sequences in the area surrounding the tumour without affecting the healthy cells.
The invention relates to a tissue-conditioning kit comprising a terpenic anti-fungal agent exhibiting activity against Candida albicans present in subprosthetic stomatitis. The kit comprises a powder polymer, a plasticiser, and a mixture of terpenes with anti-fungal activity. In another embodiment of the kit, the terpenic anti-fungal agent is contained in the plasticiser. The invention also relates to the use of the tissue-conditioning kit for treating subprosthetic stomatitis, as it allows the reduction of lesions in the buccal mucosa of patients.
METHOD OF PRODUCING A BIOFERTILIZER COMPRISING FERMENTATION IN THE SOLID STATE, IMMOBILIZATION BY MEANS OF ALLOPHANE NANOPARTICLES AND RENEWED FERMENTATION, AND BIOFERTILIZER
The invention concerns a method of producing a biofertilizer, comprising: (a) fermentation in the solid state, in order to produce key nutrients and enzymes for plant nutrition; (b) immobilizing by means of allophane nanoparticles the enzymes and substrates produced in step (a); and (c) renewed fermentation in order to encourage the development of microorganisms which improve the quality of the biofertilizer. The invention further concerns the biofertilizer produced by this method.
A dental system for holding a pre-existing prosthesis with at least one mini-implant having a head portion, the system comprising: a retention bar comprising a base and at least one housing configured to allow accommodation of the head portion of the mini- implant; a bar clamp capable of engaging the base of the retention bar; a retention hook capable of snapping onto the bar clamp; and a removable elastic cover, wherein the retention hook is capable of attaching to and retaining the dental prosthesis, and wherein the elastic cover completely covers the housing of the retention bar.
The invention relates to a functional drink based on Chilean vitis vinífera grape juice enriched with polyphenols of an intermediate molecular weight, extracted from red grape varieties. This drink generates biological effects beneficial for cardiovascular health as it has an anti-inflammatory and hypolipemic effect, as well as improving the dependent nitric oxide vasodilatory capacity.
The invention relates to an electric arc system having a controlled atmosphere, which operates continuously to produce nanometric material and includes the following components: (a) a supply section, consisting of welding equipment, precursor electrodes and gas feeders; (b) a discharge and reaction section in which the electric arc reaction takes place, which consists of a stainless-steel reaction chamber that is longitudinal in shape in order to promote the movement of the particles; (c) a surface load acceleration system (ASC); and (d) an accumulation and release section, in which the nucleation and growth process of the nanostructures is completed, which consists of a chamber, the sides of which are provided with cavities equipped with gloves and a quartz connector. In addition, the process is protected in order to obtain nanometric material from the electric arc system.
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
B01J 19/08 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor
H01H 1/48 - Contacts characterised by the manner in which co-operating contacts engage by sliding with provision for adjusting position of contact relative to its co-operating contact
92.
FERTILISER FOR IMPROVING DEGRADED SOILS AND METHOD FOR THE PRODUCTION THEREOF
The invention relates to a fertiliser for improving degraded soils, especially in terms of sulfur and calcium content, consisting of: (a) between 40 and 60 wt. % of fly ash from biomass combustion, (b) between 10 and 30 wt. % of secondary sludge from the paper industry; and (c) between 10 and 50 wt. % of gypsum; where the secondary sludge provides lignin which acts as a chelating agent.
A reinforced metal roller used for the manufacture of steel products that comprises at least the following components: a metal body, the form of which is preferably that of a disc type, with a thickness of between 2 and 500 mm; carbon, glass, aramid or mixed fibres, with a planar density of between 100 and 600 g/m2, in a content of between 30 and 55% by volume; a heat-stable polymer matrix in a content of between 70 and 45% by volume; an activator, in a resin percentage of between 0.3 and 25% by volume; and nanoreinforcements to between 0.05 and 3% by weight of the resin. Furthermore, the application relates to the method for the production of said roller.
F16C 13/00 - Rolls, drums, discs, or the likeBearings or mountings therefor
B29C 39/10 - Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressureApparatus therefor for making articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. casting around inserts or for coating articles
B29C 63/00 - Lining or sheathing, i.e. applying preformed layers or sheathings of plasticsApparatus therefor
94.
INTER-CELL CURRENT-MODULATING BAR FOR ELECTROLYTIC APPLICATIONS PROVIDED WITH ELECTRICAL RESISTANCES BETWEEN CATHODE-ANODE INTER-CELL CONNECTORS
The invention relates to an inter-cell current-modulating bar for electrolytic processes, comprising electrical resistances in the micro-ohm range, located between high-conductivity cathode-anode inter-cell connectors.
This technology comprises compounds derived from 1,3,4-thiadiazole alkylamides and chalcone, which inhibit the activation of the TRPV-1 receptor by means of capsaicin and temperature. Said compounds have a strong antagonist activity in the mode of activation of the TRPV-1 receptor by capsaicin and by temperature. The invention also relates to the use of said compounds in the treatment of diseases wherein the TRPV-1 receptor is overactivated, such as chronic pain.
The invention relates to a prosthetic retention system for edentulous patients, formed by a prefabricated bar and two implants. According to the invention, the aforementioned bar is formed by a tubular central part having a round or ovoid-like cross-section and two hollow caps at the ends thereof, and the implants are formed by a single part comprising an upper area that is connected to the bar and a lower area forming the section that is inserted into the bone of the patient.
The invention relates to a process for producing tall oil by reacting tall oil soap with a sodium sesquisulfate solution. The process includes the following steps: (a) determining the concentration of sodium sequisulfate; (b) reacting the sodium sesquisulfate solution and the tall oil soap; and (c) separating the tall oil and brine phases.
The invention relates to a probiotic food for salmonids, including at least one lactic acid strain, obtained from said salmonids, and having immunostimulant and protective properties; and to the method for preparing same, including the following steps: (a) introduction of a source of carbon and the inoculum of at least one probiotic strain into a fermenter, (b) addition of nutritional components, (c) cold extrusion of the mixture, (d) formation of pellets, and (e) drying of the pellets.
The invention relates to a probiotic functional food comprising: a biomass of Lactobacillus spp. strains conditioned to withstand temperatures of between -30 and -40 °C, and cryoprotective agents. Said food comprises jellies, desserts, juices and/or milk derivatives, preferably ice cream. This functional food is intended for patients undergoing therapies such as chemotherapy and/or radiotherapy, since it counteracts the side-effects cancer treatment.
A23G 9/36 - Frozen sweets, e.g. ice confectionery, ice-creamMixtures therefor characterised by the composition containing microorganisms or enzymesFrozen sweets, e.g. ice confectionery, ice-creamMixtures therefor characterised by the composition containing paramedical or dietetical agents, e.g. vitamins
A23L 1/09 - containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin (A23L 1/76, A23L 1/236 take precedence);;
100.
TRANQUILISING/SEDATING PHARMACEUTICAL FORMULATION BASED ON NEUROSTEROIDS AND A PHENOTHIAZINE DERIVATIVE FOR USE IN MAMMALS
The invention relates to technology for the veterinary domain, corresponding to a tranquilising/sedating pharmaceutical formulation, for reducing motor activity, comprising at least one neurosteroid with tranquilising activity and a tranquiliser of the phenothiazine derivative type, used as a pre-anaesthetic in mammals, preferably in small animals and in high-risk patients.
A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
C07D 279/24 - [b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
C07C 49/617 - Unsaturated compounds containing a keto group being part of a ring polycyclic a keto group being part of a condensed ring system
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