The invention relates to the in vitro use of various molecular biomarker levels measured in samples from subjects with obesity, said samples being isolated before the bariatric surgery as biomarkers for predicting or prognosing the response to bariatric surgery.
The present invention relates to an anti-bedsore device, characterised in that it comprises: an internal surface, an external surface, and a plurality of ribs made from an elastic material, attached to the internal surface and to the external surface, and located within the space defined between both surfaces, and oriented radially with respect to a central point, such that the space defined between the two surfaces forms a first cushioning chamber for cushioning a weight that is resting upon one of the surfaces.
MicrobacteriumChlamydomonasChlamydomonas for sustained hydrogen production, for obtaining large amounts of biomass and for bioremediation, particularly of waste from the dairy industry.
The invention discloses the use of rapamycin or sirolimus and statin as protectors against liver damage caused by haemolytic disorders, specifically in patients with non-alcoholic fatty liver disease.
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
5.
METHOD TO ISOLATE PROTEINS FROM MUCINOUS CARCINOMA CANCER CELLS AND USES THEREOF
The present invention refers to a method to isolate proteins from mucinous carcinoma cancer cells. The present invention also refers to the use of the proteins thus obtained as biomarkers or therapeutic targets.
The invention refers to a method for the production of microbial biocapsules comprising: (a) cultivating the filamentous fungus by vortex agitation and sonication, followed by inoculation and incubation, obtaining cultured filamentous fungal pellets and separately cultivating the microbial cells, obtaining cultured microbial cells; preparing a suspension of the pellets and the cells, in a proportion from 1:1 to 1:3 and subjecting the suspension to at least one vacuum infusion cycle, and incorporating the cells entrapped in the filamentous fungus matrix into a growth medium and incubating, obtaining the microbial biocapsules.
C12N 1/12 - Unicellular algaeCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A23C 9/12 - Fermented milk preparationsTreatment using microorganisms or enzymes
A23L 29/00 - Foods or foodstuffs containing additivesPreparation or treatment thereof
A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
The present invention relates to compounds, compositions, and combined preparations for the treatment of hepatocellular carcinoma, diagnostic methods, and methods for selecting therapeutic agents useful in the prevention, improvement, relief, and/or treatment of hepatocellular carcinoma.
A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
The present invention relates to a method for obtaining and enriching carotene blends from agri-food waste, said method being based on the use of supramolecular biosolvents (bioSUPRAS). The invention further relates to the use of carotene blends thus obtained as a food additive.
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
A23L 5/44 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
9.
PHOTOCATALYTIC COMPOSITE MATERIAL, METHOD FOR OBTAINING SAID MATERIAL AND USE OF SAME
The invention relates to a novel photocatalytic composite material made up of layered double hydroxide Ni3Ti-CO3 and different amounts of luminescent graphene quantum dots (GQDs), with persistent photocatalytic activity in the dark. The photovoltaic composite material of the invention can be used on paints and coatings, as well as in manufacturing compact construction materials.
A62D 3/37 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by reduction, e.g. hydrogenation
10.
TORSIONAL WAVE ULTRASOUND RECEIVER, DEVICE, METHODS AND ASSOCIATED USES FOR THE ASSESSMENT OF MECHANICAL PROPERTIES IN TISSUES HAVING CURVED SURFACES
The present invention relates to an ultrasound receiver that receives torsional waves from a sample (1), said receiver comprising: a flexible receiving ring (7) acoustically coupled with the sample (1); one or more perforated slots in the receiving ring (7); and one or more transducers (8) housed in the one or more slots of the receiving ring (7); the one or more transducers (8) being electrically connected to the receiving ring (7) by means of a layer of conductive material. The invention further comprises a device (2) comprising: said receiver, an ultrasound emitter (5) and a casing (12) that houses both emitter (5) and receiver. Likewise, the invention discloses a method for measuring mechanical parameters of the sample (1) by using the device (2).
B06B 1/06 - Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
The present invention relates to an anti-bedsore device, characterised in that it comprises: an internal surface, an external surface, and a plurality of ribs made from an elastic material, attached to the internal surface and to the external surface, and located within the space defined between both surfaces, and oriented radially with respect to a central point, such that the space defined between the two surfaces forms a first cushioning chamber for cushioning a weight that is resting upon one of the surfaces.
Disclosed is a direct-injection spraying device for agricultural vehicles, which comprises: a first tank containing water; a first water pipe fluidly connected to an outlet of the first tank; at least one dispenser designed to add at least one liquid, solid or gaseous active substance to the water that travels through the first pipe, to form a mixed solution; and a set of spraying nozzles to apply the mixed solution to a crop, wherein the device also comprises respective means for controlling the pH and temperature of the water that forms the mixed solution.
The invention discloses an intravenous infusion device (1) comprising a casing (2) having a duct (211) configured for the passage of a catheter (100) and selective restriction means for said catheter (100), where the restriction means comprise a motor (3) having a threaded shaft (31) and a locking component (4) coupled to said threaded shaft (31), said locking component (4) being disposed within a channel (212) that is provided in the casing (2) and communicates with the duct (211). Thus, when the motor (3) turns the threaded shaft (31), walls of the channel (212) in the casing (2) prevent the locking component (4) from turning, displacing the locking component (4) along the threaded shaft (31) to selectively block an opening in the duct (211) along which the catheter passes.
Compounds, compositions and combined preparations for the treatment of hepatocellular carcinoma, diagnostic methods and methods for the selection of therapeutic agents useful for the prevention, improvement, relief and/or treatment of hepatocellular carcinoma.
A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
Disclosed is an active sampling device comprising a fan on the blades of which a sorbent material is disposed, and a method for monitoring volatile compounds in the air.
INSTITUTO NACIONAL DE INVESTIGACIÓN Y TECNOLOGÍA AGRARIA Y ALIMENTARIA (INIA) (Spain)
UNIVERSIDAD DE ALCALÁ (Spain)
Inventor
Alonso Águila, Raúl
Rodríguez Fernández-Alba, Antonio
Hernando Guil, María Dolores
Rodríguez Fernández-Alba, Amadeo
Gómez Ramos, María José
Cutillas Juárez, Víctor Manuel
Ferrer Amate, Carmen María
Valverde García, Antonio
Flores Serrano, José Manuel
Abstract
The present invention relates to a process for the treatment of beeswax from beekeeping farms, contaminated with residues of veterinary and phytosanitary treatments by means of a process of extraction of the molten wax with methanol and the subsequent steps for the adaptation of the wax obtained to manufacture hives therefrom that are accepted by the bees, and that can also be used in galenic formulations. Therefore, the technological framework in which this invention is included is that of beekeeping and, more specifically, beeswax extraction processes and devices.
The invention relates to a method for predicting or prognosing the response to treating cancer with antiangiogenics, and specifically for predicting the response to treating colorectal cancer with bevacizumab.
The invention relates to a method for obtaining data useful for the diagnosis, stratification and/or follow-up of patients with rheumatoid arthritis. Kit or device and uses thereof.
The invention relates to biomarkers, a method, a diagnostic kit and uses for diagnosing, predicting or prognosing the development of prostate cancer (PCa) in an individual.
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
21.
METHOD FOR PREDICTING OR PROGNOSING THE DEVELOPMENT OF TYPE 2 DIABETES MELLITUS IN AN INDIVIDUAL
The invention relates to biomarkers, a method, a diagnostic kit and uses for predicting or prognosing the development of type 2 diabetes mellitus in an individual.
A method for obtaining data useful for the diagnosis, stratification and/or follow-up of patients with rheumatoid arthritis. Kit or device and uses thereof.
The invention describes a machine formed by a frame in the form of a closed rectangular prism, and a top cover and a bottom cover that fit to the perimeter of the frame and seal it. The machine also comprises an intermediate cover having at least one opening made in the body thereof and configured to accommodate a flat sheet specimen with a non-stick coating. The machine can include a system of electrical resistors with adjustment and control of the temperature inside the machine, and a system with a floating cover to exert pressure inside a mould.
CONSORCIO CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED, M.P. (Spain)
Inventor
Rangel Zúñiga, Oriol Alberto
Yubero Serrano, Elena María
López Miranda, José
Pérez Martínez, Pablo
Camargo García, Antonio
Jiménez Lucena, Rosa
Alcalá Díaz, Juan Francisco
Delgado Lista, Javier
León Acuña, Ana
Torres Peña, José David
García Ríos, Antonio
Gómez Delgado, Francisco
Abstract
The invention relates to markers and a method for predicting or forecasting individuals with greater risk of developing diabetes mellitus, kit or device, and uses thereof.
The present invention relates to a device intended for reproductive use, which is based on a device having a flexible body for packaging and freezing semen, preferably animal semen, and which allows the body of the device to be completely straight when the content thereof is to be used after thawing, or allows the body to be bent during filling and preservation.
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (Switzerland)
Inventor
Jodolowski, Alexander Zachary Davis
Roldan Carmona, Cristina
De Miguel Rojas, Gustavo
Camacho Delgado, Luis
Nazeeruddin, Mohammad Khaja
Abstract
31_x33 perovskite shows enhanced thermal stability and intrinsically new structural and optoelectronic properties. This allows for stable and high-power conversion efficiencies over 20%, a fundamental step within the perovskite field.
The present invention related to a method for producing and enriching carotenoids from biomass based on the use of nanostructured liquid phases, and use of the carotenoids thus produced as food additives and in the pharmaceutical industry
The present invention relates to the use of peptides derived from the extracellular end of truncated receptor sst5TMD4 as markers in a method for diagnosing and/or predicting cancer in a patient, and to a diagnostic kit or device. The present invention also relates to the use of peptides derived from the extracellular end of truncated receptor sst5TMD4 as therapeutic targets in cancer.
09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
38 - Telecommunications services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific, nautical, surveying, photographic, cinematographic, optical, weighing, measuring, signalling, checking (supervision), life-saving apparatus and instruments; Apparatus and instruments for conducting, switching, transforming, accumulating, regulating or controlling electricity; Mechanisms for coin-operated apparatus; cash registers, calculating machines; Fire-extinguishing apparatus. Paper and cardboard; Flyers; Posters; Stationery and educational supplies; Adhesives for stationery; Jotters; Stickers [stationery]; Directories; Paper badges; Bags [envelopes, pouches] of paper or plastics, for packaging; Boxes of cardboard or paper; Printed advertisements. Services de télécommunications; Accès à du contenu, à des sites et à des portails internet; Fourniture d'accès à des bases de données; Assistance en matière de télécommunications; Communication par voie électronique; Diffusion d'émissions de radio et de télévision; Distribution de données ou d'images audiovisuelles par le biais d'un réseau informatique mondial ou d'Internet; Service de communication audiovisuelle; Émission de programmes radiophoniques et télévisés, également par le biais d'un réseau câblé et de l'internet; Expédition de dépêches; Fourniture d'accès à un réseau informatique mondial pour le transfert et la diffusion d'information; Fourniture d'accès à des blogs; Fourniture de forums de discussion en ligne pour la transmission de messages entre des utilisateurs d'ordinateurs; Fourniture de salons de discussion [chat] en ligne pour des réseaux sociaux; Téléconférences audio; Transmission électronique de programmes informatiques via Internet; Services de télécommunications. Publication of books and texts, other than publicity texts; Publication of books. Services scientifiques et technologiques ainsi que services de recherches et de conception y relatifs; Services d'analyses et de recherches industrielles; Conception et développement d'ordinateurs et de logiciels; Maintenance et mise à jour de logiciels; Prestation de services informatiques pour logiciels; Services de conseils et de consultation en matière d'ordinateurs et de logiciels informatiques.
09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
38 - Telecommunications services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Magnetic data carriers, recording discs; Compact discs, DVDs and other digital recording media; Memory sticks; Data processing equipment, computers; Computer software; Computer software downloadable from global computer information networks; Downloadable publications; Electronic dictionaries; Scientific, nautical, surveying, photographic, cinematographic, optical, weighing, measuring, signalling, checking (supervision), life-saving and teaching apparatus and instruments; Apparatus and instruments for conducting, switching, transforming, accumulating, regulating or controlling electricity; Apparatus for recording, transmission or reproduction of sound or images; Mechanisms for coin-operated apparatus; cash registers, calculating machines; Fire-extinguishing apparatus. Paper and cardboard; Forms, printed; Flyers; Books; Catalogues; Magazines [periodicals]; Educational publications; Manuals for teaching and training purposes; Posters; Stationery and educational supplies; Adhesives for stationery; Agendas; Jotters; Stickers [stationery]; Photographs; Geographical maps; Directories; Paper badges; Bags [envelopes, pouches] of paper or plastics, for packaging; Boxes of cardboard or paper; Computer programmes in printed form; Printed advertisements. Telecommunication services; Access to content, websites and portals; Providing access to databases; Consultancy on telecommunications; Communication by electronic means; Radio and television broadcasting; Distribution of data or audio visual images via a global computer network or the internet; Audiovisual communication services; Broadcasting of radio and television programmes, including via a cable network and via the internet; Sending of telegrams; Providing access to a global computer network for the transfer and dissemination of information; Providing access to weblogs; Providing on-line forums for transmission of messages among computer users; Providing on-line chat rooms for social networking; Audio teleconferencing; Electronic transmission of computer programs via the internet; Telecommunication services. Tuition; Providing of training; Entertainment; Sporting and cultural activities; Providing of information relating to education, entertainment and sport; Arranging of trade fairs and exhibitions for cultural or educational purposes; Publication of books and texts, other than publicity texts; Publication of books; Providing on-line electronic publications, not downloadable; Providing publications from a global computer network or the internet which may be browsed; On-line library services, namely, providing electronic library services which feature newspapers, magazines, photographs and pictures via an on-line computer network; Arranging and conducting of competitions (education or entertainment), organisation of awards; Arranging of colloquiums, conferences and congresses; Museum facilities (Providing -) [presentation, exhibitions]; Production of shows and live theatre productions; Conducting guided tours of cultural sites for educational purposes. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software; Maintenance and updating of computer software; Application service provider services; Advice and consultancy in the field of computers and computer software.
The present invention relates to a method for obtaining mesoporous biosilica from rice husks, which comprises the following steps: (a) obtaining rice husk particles by grinding and sieving the rice husks; (b) adding an acid solution to the particles obtained in step (a); and (c) extracting biosilica by irradiating the solution obtained in step (b) in microwaves. The present invention also relates to the use of the mesoporous biosilica obtained using said method, and in particular to the use of said biosilica to obtain metallic nanomaterials.
Biomarkers and early diagnostic method for diagnosing growth hormone deficiency in prepubescent childen, and/or a disease associated with growth hormone deficiency.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
34.
METHOD FOR PRODUCING EXTRACTS ENRICHED WITH SULFOXIDE-FREE ORGANOSULFUR COMPOUNDS, S-ALKENYL-L-CYSTEINE AND S-ALKYL-L-CYSTEINE, FROM PLANT RAW MATERIALS, AND USES THEREOF IN THE TREATMENT OF INFLAMMATORY DISEASES
The present invention relates to a high-yield method for the production of extracts enriched with organosulfur compounds of the S-alkenyl-L-cysteine and S-alkyl-L-cysteine type. Said compounds are obtained from plants of the genus Allium and are free of sulfoxides. In addition, the invention relates to the use of the organosulfur compounds of the S-alkenyl-L-cysteine and S-alkyl-L-cysteine type as therapeutic or nutraceutical agents in the prevention and treatment of human and animal diseases associated with chronic inflammation.
C07C 323/58 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
35.
USE OF IN1-GHRELIN FOR THE DIAGNOSIS OF PROSTATE CANCER
The present invention relates to a method for diagnosing and/or predicting cancer in a patient. In particular, the present invention relates to methods for diagnosing and/or predicting cancer that comprise: quantifying levels of In1-ghrelin expression in a plasma sample isolated from an individual; comparing the levels obtained with the levels of In1-ghrelin expression in a reference sample; and assigning the patients who show In1-ghrelin expression levels that are statistically significant and higher than the levels of the reference sample, to the group of individuals at risk of cancer. The present invention also provides a diagnostic method for bladder and/or colon cancer, which comprises quantifying expression levels of In1-ghrelin, GOAT and/or GHS-R1b in tissue samples. The present invention also relates to a small interfering RNA (siRNA) useful in a cancer treatment method.
The invention relates to a gene construct that codifies a new gene and/or the family thereof, providing resistance to abiotic stresses. In particular, the invention relates to a gene construct comprising the sequence SEQ ID NO.: 1 or a sequence that is at least 75% identical to the sequence SEQ ID NO.: 1. The invention also relates to a method for developing strains of microorganisms that are resistant to abiotic stresses using the gene construct according to the invention.
A surgical robotic system (1) comprising: robotic units, each one being independent from the others, each comprising a support (11) and a robotic arm assembly (12); said support (11) comprising motion means and configured to change position and orientation of the support (11) with respect to the table (3); said robotic arm assembly (12) comprising: a robotic arm (15), a surgical tool (18) coupled thereto and a force sensor (16) configured to receive measurement of forces and torques applied by the tool (18). The system also comprises a control console (7) configured to remotely operate said robotic units, comprising: computing means (42); haptic devices (8) configured to control the movement, spatial orientation and aperture/ closure of the distal end of the tool (18), each haptic device (8) being configured to control one robotic arm (15); selection means (51) configured to activate/deactivate the robotic arms (15); a monitor (701) configured to show a 3D image.
A61B 34/00 - Computer-aided surgeryManipulators or robots specially adapted for use in surgery
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
B25J 19/00 - Accessories fitted to manipulators, e.g. for monitoring, for viewingSafety devices combined with or specially adapted for use in connection with manipulators
The tool coupling comprises a first tool part (4) and a second tool part (14), the second tool part (14) being movable in relation to the first tool part (4),. The tool coupling comprises a first base part (6) for detachably retaining the first tool part (4) and a second base part (16) movable in relation to the first base part (6) for detachably retaining the second tool part (14). The first base part (6) comprises a pusher (11) movable in relation to the first base part (6) for detaching the first tool part (4) and the second base part (16) comprises a cap (21) movable in relation to the second base part (16) for detaching the second tool part (14).
The invention relates to the use of micro-RNAs: miR-124, miR-145, miR-20a, miR-296, miR-34a, miR-374, miR-19b, and miR-15a, for the diagnosis, classification and/or monitoring of a person who may have primary antiphospholipid syndrome, a method for obtaining data that can be used for the diagnosis, classification and/or monitoring of primary antiphospholipid syndrome in a person who may have antiphospholipid syndrome, as well as a kit or device, and a microarray and uses of same.
The invention relates to the use of micro-RNAs: miR-146a, miR-122, miR-148a, miR-214, miR-372, miR-let7c, miR-30c, miR-19a, miR-193b, miR-29b and mi RNA-17, for the diagnosis, classification and/or monitoring of lung cancer, a method for obtaining data that can be used for the diagnosis, classification and/or monitoring of a person who may have lung cancer, as well as a kit or device, and a microarray and uses of same.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Spain)
UNIVERSIDAD DE CÓRDOBA (Spain)
Inventor
García Frutos, Eva María
Camacho Delgado, Luis
De Miguel Rojas, Gustavo
Abstract
The invention relates to the use of 7,7'-diazaisoindigo derivative compounds as components for producing solar cells, specifically organic photovoltaic cells. The invention also relates to novel 7,7'-diazaisoindigo derivative compounds substituted in positions 5,5', preferably by halogen atoms.
The present invention relates to the use of levels of the quantity or concentration of ghrelin O-acyltransferase (GOAT) enzyme or of the mrNA that encodes this protein, said levels being obtained ex vivo from a biological sample isolated from a subject, as an efficient tool for obtaining data that can be used in the clinical diagnosis of prostate cancer.
CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (CIBER) (Spain)
Inventor
De La Mata García, Manuel
González Rubio, Sandra
Ferrín Sánchez, Gustavo
Abstract
The invention relates to the use of a retinoic acid derivative to produce a drug for the relief, improvement, prevention and/or treatment of cholestatic liver disease. The invention also relates to the composition, pharmaceutical form and uses thereof.
The invention relates to a method for obtaining data that can be used for the diagnosis, classification and monitoring of lung cancer, to a kit or device, and to the use thereof.
The invention relates to the use of the gene KIR 2DL2 and/or KIR 2DS2 or the expression products thereof for collecting data used to predict or forecast the development of thrombocytopenia induced by interferon, preferably pegylated interferon-alpha, following treatment with said drug in individuals infected by the hepatitis C virus, preferably genotype 1.
The invention relates to a method for obtaining useful data about the angiogenesis in a patient's lower limbs, and particularly in the lower limbs of patients with diabetes subjected to treatment.
The invention relates to a method for producing data that can be used for the classification, diagnosis and monitoring of lung cancer, to a kit or a device and to the uses thereof.
The invention relates to the use of the intracellular content of mesenchymal stem cells in individuals for stimulating the survival, regeneration and/or repair of the damaged organ and/or tissue. The invention also relates to the use of said lysate for producing a pharmaceutical composition comprising said intracellular content, and to the use thereof in the regeneration and/or repair of the damaged organ and/or tissue.
FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DE CÓRDOBA (Spain)
Inventor
López-Pedrera, Rosario
Pérez-Sánchez, Carlos
Castro Villegas, Carmen
Limón-Ruiz, Patricia
Jiménez Gómez, Yolanda
Collantes Estévez, Eduardo
Barbarroja Puerto, Nuria
Abstract
The present invention relates to a method of predicting response of a human subject to anti-TNFa therapy, and preferably wherein the subject is suffering from rheumatoid arthritis.
CENTRO DE PRODUCCION MULTIMEDIA PARA LA TV INTERACTIVA (CPMTI, S.L.) (Spain)
Inventor
De Castro Lozano, Carlos
García Salcines, Enrique
Ramírez Uceda, José Miguel
Robles Gonzáles, Remedios María
Malgina, Natalia
López Coronado, Miguel
Sainz De Abajo, Beatriz
Abstract
The invention relates to a high-precision radar system comprising: a microwave channel module (4); a transmitter module (3) which generates wave pulse signals in the millimetric band and synchronisation pulse signals; a receiver module (5) which receives and processes the signals reflected from the target; an administration and supply module (6) with a synchronisation and control module (28) for transmitting control orders to the transmitter (3) and receiver (5) modules; a computerised radiolocation post (7) with a radar processor module (32); and a motor block (2) for rotating the antenna module (1), comprising: a module (34) for detecting the position of the antenna, which transmits the information about the angular position of the antenna module (1) to the synchronisation and control module (28); and a rotary connection element (33) for establishing a contactless connection between the antenna module (1) and the transmitter (3) and receiver (5) modules.
G01S 13/10 - Systems for measuring distance only using transmission of interrupted, pulse modulated waves
G01S 7/03 - Details of HF subsystems specially adapted therefor, e.g. common to transmitter and receiver
H01Q 3/04 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system using mechanical movement of antenna or antenna system as a whole for varying one co-ordinate of the orientation
51.
PULSED PLASMA REACTOR AND THE APPLICATION THEREOF FOR TRANSFORMING HYDROCARBONS INTO GRAPHENES
The invention relates to a plasma-generating device, to a plasma reactor comprising a plasma-initiating device that allows the formation of plasma with any gas by applying a RF potential via an electrode, without having to initiate it with another contributing gas. Furthermore, said plasma is used in the decomposition of hydrocarbons and other compounds for producing graphenes.
The invention relates to a method for obtaining useful data for classification, diagnosis and monitoring of lung cancer. The invention also relates to a kit for classification, diagnosis and monitoring, and to the uses thereof.
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
53.
DEVICE FOR REDUCING AERODYNAMIC RESISTANCE IN VEHICLES
The invention relates to a device for reducing aerodynamic resistance, comprising a plurality of ailerons that can be fitted to the rear surface of a vehicle, said ailerons being designed to form a multi-cavity on said rear surface, created by at least four cavities, where said cavities have a preferably square or rectangular form. The invention provides a significant improvement in the reduction of aerodynamic resistance in vehicles, especially in lorries, compared to other known devices. Furthermore, the device of the invention can be fitted in a simple and automatable manner.
FUNDACIÓN PÚBLICA ANDALUZA PROGRESO Y SALUD (Spain)
FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DE CÓRDOBA (Spain)
UNIVERSIDAD DE CÓRDOBA (Spain)
Inventor
Almadén Peña, Yolanda
Herencia Bellido, Carmen
Muñoz Castañeda, Juan Rafael
Abstract
The invention relates to the use of the intracellular content of individual mesenchymal stem cells with acute liver damage in order to stimulate the survival, regeneration and/or repair of the damaged organ. The invention also relates to the use of this lysate for the production of a pharmaceutical composition comprising said intracellular content, intended to stimulate the survival, regeneration and/or repair of organs, specifically the liver.
A61K 35/28 - Bone marrowHaematopoietic stem cellsMesenchymal stem cells of any origin, e.g. adipose-derived stem cells
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
55.
ANGIOTENSIN-CONVERTING ENZYME POLYMORPHISMS FOR PREDICTING OR PROGNOSTICATING THE RESPONSE TO ANTIANGIOGENIC CANCER TREATMENT
The invention concerns a method and kit for predicting or prognosticating an individual's response to treatment with a thymidine synthesis inhibitor, an alkylation agent and a vascular endothelial growth factor antagonist in a cancer patient, in particular an individual suffering from cancer of the colon.
The invention relates to a formulation for producing a paste for stuffing pitted olives using natural vegetable products, and to the method for producing same.
The invention relates to the use of the KIR3DS1 gene for predicting or forecasting the response of an individual to the treatment of HCV with peg-IFN in addition to a guanosine analogue, preferably ribavirin (RBV). The invention also relates to a method, a kit and uses.
The invention relates to the use of the growth factor derived from platelets or any of the like, biologically active fragments or variants, or from the agonists of the AT2 receptor, angiotensin, angiotensin II or any of the like, biologically active fragments or variants, or any of the combinations thereof, and the pharmaceutical compositions thereof, in the production of a medicament for the prevention or treatment of vascular calcification.
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
59.
SYSTEM FOR PROTECTING REFRIGERATION COMPRESSORS IN REFRIGERATION SYSTEMS AND HEAT-PUMP HEATING SYSTEMS
The invention relates to a system for protecting refrigeration compressors in refrigeration systems and heat-pump heating systems, comprising a control system (8) into which are input the signal from a pressure sensor arranged at the inlet of the exchanger (6) in the secondary circuit (2) and the signal from a pressure sensor arranged at the outlet of the exchanger (7) in the primary circuit, and which has an outlet connected to the compressor (4) and to automatic valves (9) arranged at the inlet and the outlet of the compressor (4). The signals received from the pressure sensors (6, 7) at the inlet and at the outlet of the exchanger are compared with a pre-determined value in the control system (8), and if the values differ, a signal is sent to stop the compressor (4) and the automatic valves (9).
The invention relates to a system and method for the remote management of a supercomputing platform using a web interface, by means of a user interface (100) via a web browser (502) of a client station (504). The method comprises: dynamically generating a computation initialisation form (112) for the introduction of parameters, initial conditions and contour conditions of the problem, including obtaining the concrete model (200) of the problem to be solved, loading an XML metadata structure (202) associated with said model, using an advanced XSL style template (204) to transform (206) the XML structure, and obtaining the parameters, initial conditions and contour conditions of the problem for the subsequent execution in the cluster (508); selecting execution parameters (120) for executing the processes to be executed in the cluster (508); including data and compiling (122) the resulting code according to the execution parameters selected by the user; and executing (126) the resulting code in computing nodes of the cluster (514).
The invention relates to the use of coenzyme Q-10 and the compositions thereof in the production of a drug for the prevention and treatment of renal lesions associated with stones in the urinary tract.
A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61P 13/04 - Drugs for disorders of the urinary system for urolithiasis
62.
USE OF BIOCAPSULES OF YEAST AS FERMENTATION AGENTS IN THE SECOND ALCOHOL FERMENTATION IN THE BOTTLE AND APPLICATION THEREOF IN PREPARING SPARKLING WINE AND SPARKLING ALCOHOLIC BEVERAGES
The invention relates to the use of immobilizing yeasts in biocapsules and to the application thereof in producing sparkling wine prepared from the second alcohol fermentation in the bottle performed by said yeasts. The invention includes producing biocapsules in a suitable concentration and the application of same as biocatalyzers in a particular industrial fermentation process.
CIBER FISIOPATOLOGÍA DE LA OBESIDAD Y NUTRICIÓN (CIBERobn) (Spain)
Inventor
Delgado Lista, Francisco Javier
Pérez Martínez, Pablo
López Segura, Fernando
López Miranda, José
Pérez Jiménez, Francisco
Rangel Zúñiga Oriol, Alberto
Luque De Castro, María Dolores
Abstract
The invention relates to the use of phenolic compositions of olive oil in a determined concentration, for developing a medicament or pharmaceutical or food composition for the prevention or treatment of arteriosclerosis in humans.
Method for authenticating digital artworks (1). The method comprises a stage of recording a security code (6) in the artwork (1) and subsequently verifying said code. The authenticity of the artwork (1) is verified in a verification room (5) which comprises a bispectral camera (3), a rail (4) on which the camera (3) is moved, spotlights (2) and a luxmeter (7). The recording stage comprises the steps of: storing the digital artwork (1) in a database (C4) and generating a security code (6); printing the artwork (1) in visible ink; and printing the security code (6) in ultraviolet ink on the artwork (1) which has already been printed.
G06F 17/30 - Information retrieval; Database structures therefor
G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
The invention relates to a method for producing carbon nanotubes in the absence of metal catalysts which, starting with a carbon source, is characterised by comprising the steps of: generating the plasma at atmospheric pressure using gases in which said generation takes place in a container coupled with the energy generator which supplies the power required to create the plasma; mixing the carbon-containing substance with a carrier gas; injecting the mix of the carbon source and the carrier gas into the container where the plasma is created; and forming the nanocarbon material on a substrate at the plasma outlet.
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (USA)
Inventor
Benito Lopez, Pedro
Castaño Fuentes, Justo Pastor
Cordoba Chacon, José
Gahete Ortiz, Manuel David
Gracia Navarro, Francisco
Kineman, Rhonda Denise
Luque Huertas, Raul Miguel
Martinez Fuentes, Antonio Jesús
Abstract
The invention relates to a novel splicing variant of ghrelin/obestatin, called In2-ghrelin, and to the use alone and/or in combination with ghrelin-O-acyltransferase (GOAT) and/or the truncated ghrelin receptor (GHS-R1b), for obtaining useful data in the diagnosis, prognosis and monitoring of breast cancer, hypophysis tumours, and tumours of the ovary, endometrium and cervix.
The invention relates to the use of a microorganism of the Beauveria bassiana species for protecting a woody plant against attack from Euzophera pinguis Haw.
The invention relates to a composite negative electrode material comprising a transition metal malonate of general formula (I) MC3H2O4, wherein M represents one or more transition metals, a polymer binder and an agent providing electronic conduction.Such a material produces total reversible capacity > 372 mAh/g in the potential range of 0.0-3.0V. The invention also relates to a method for the preparation of some metal malonates by the inverse micelle process, and to transition metal malonates obtained by such a method.
H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
C07C 69/00 - Esters of carboxylic acidsEsters of carbonic or haloformic acids
69.
IMMUNOGENIC AND THERAPEUTIC COMPOSITIONS FOR STREPTOCOCCUS SUIS
The present invention refers to protein Ssu05_0473 and protein Ssu05_0272 or immunogenic derivatives thereof for use as a medicament, in particular for use as a medicament against Streptococcus suis colonization or infection in humans and animals. The present invention also refers to a vaccine comprising at least one of said proteins or immunogenic derivatives thereof, to a method for the diagnosis of bacterial infections using said proteins or immunogenic derivatives thereof and to a kit for the diagnosis of Streptococcus suis infections.
C07K 14/315 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
70.
METHOD FOR DETECTING, IDENTIFYING AND QUANTIFYING PERONOSPORA ARBORESCENS BY REAL-TIME QUANTITATIVE PCR
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (Spain)
Inventor
Landa Del Castillo, Blanca
Jiménez Díaz, Rafael Manuel
Montes Borrego, Miguel
Abstract
The method for quantifying Peronospora arborescens by quantitative PCR (qPCR) in a biological sample comprises extracting the DNA contained in said biological sample and amplifying that DNA by means of qPCR. The invention is of use in the quantification of P. arborescens.
The invention relates to a microorganism of the species Beauveria bassiana, capable of systemically protecting the plant Papaver somniferum from attack by the insect Iraella luteipes or a mutant of said microorganism which retains said capacity for the systemic protection of a plant against attack by I. luteipes.
The present invention relates to a method for preventing and correcting iron chlorosis in plants, characterised in that said method includes applying an aqueous suspension of synthetic siderite to the soil in which the plants are grown, the siderite suspension preferably being applied in a ratio of 0.5 to 1.0 g of siderite per kg of soil.
The invention relates to a method for the fortification of a food, preferably a fat and a liquid for consumption and more preferably an oil. The method comprises the following steps in which: the food is mixed with a source of one or more nutraceutical substances, preferably a biophenol source, and ultrasound is applied to the mixture, wherein the liquid can take the form of milk or juice and the oil can take the form of olive oil, sunflower oil and soya-bean oil.
B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations
74.
ISOFORMS OF HUMAN SOMATOSTATIN RECEPTOR TYPE 5 PRODUCED BY ALTERNATIVE PROCESSING AND OLIGONUCLEOTIDE PAIRS FOR DETECTION THEREOF BY PCR
The present invention concerns two human nucleic acids comprising sequences which code two novel isoforms of human somatostatin receptor type 5 produced by alternative adjustment, called sst5B and sst5C and with possible uses in tumoral processes. Additionally, the invention concerns oligonucleotide pairs used for the differential detection of said isoforms by means of the PCR technique in different tissues.
Olea europaea cultivar is provided that forms attractive black olives having a high oil content. The fruit weight is greater than that of the ‘Arbequina’ cultivar (non-patented in the United States). The tree possesses low vigor and displays a compact and weeping growth habit that is well adapted for growing in high density orchards. The tree also displays an ability to form an olive crop at an early age.
Method for obtaining squalene from distillates from the physical refining of olive oil. The method comprises performing an alkaline saponification of the raw material in the presence of a hydrotrope and a high-vacuum molecular distillation of the unsaponifiable fraction.
The invention concerns a method for obtaining squalene from oils of animal origin, preferably from shark liver oil. The method involves subjecting the raw material to alkaline saponification in the presence of a hydrotope and molecular distillation of the unsaponifiable fraction in a high vacuum.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (Spain)
Inventor
Muñoz Ledesma, Francisco Javier
Jiménez Díaz, Rafael Manuel
Landa Del Castillo, Blanca
Montes Borrego, Miguel
Abstract
The method for detecting and identifying Peronospora arborescens is based on amplification of specific regions of said pathogen. To do this, a number of oligonucleotide primers specific for P. arborescens were designed, by means of enzymatic amplification reaction, for identifying and detecting said pathogen. This method is useful in agriculture and provides an early diagnosis of the disease (mildew) during asymptomatic states of plants, which facilitates efficient control thereof, and sanitary certification of the seed thereby preventing distribution of the pathogen in growing areas where it is not present.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
79.
METHOD FOR PRODUCING BIODIESEL USING PORCINE PANCREATIC LIPASE AS AN ENZYMATIC BIOCATALYST
The invention relates to a method for producing biodiesel, comprising the transesterification reaction of a starting product selected from one or more oils, one or more fats and mixtures of same in the presence of porcine pancreatic lipase as an enzymatic biocatalyst at a pH of at least 8, preferably at least 10. The invention also relates to the use of said method for the production of biodiesel and glycerin.
C12P 7/64 - FatsFatty oilsEster-type waxesHigher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl groupOxidised oils or fats
C10G 3/00 - Production of liquid hydrocarbon mixtures from oxygen-containing organic materials, e.g. fatty oils, fatty acids
09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
38 - Telecommunications services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific, nautical, surveying, photographic, cinematographic, optical, weighing, measuring, signalling, checking (supervision), life-saving and teaching apparatus and instruments; apparatus for conducting, switching, transforming, accumulating, regulating or controlling electricity; apparatus for recording, transmission or reproduction of sound or images; magnetic data carriers, recording discs; CD-ROMs; downloadable electronic publications; magnetic cards; automatic vending machines and mechanisms for coin-operated apparatus; cash registers, calculating machines, data processing equipment and computers; fire-extinguishing apparatus. Paper, cardboard and goods made from these materials, not included in other classes; printed matter, leaflets, catalogues, magazines, books and printed publications; printed matter; bookbinding material; maps, posters, transfers, cards, photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); printers' type; printing blocks. Telecommunications services; communications by worldwide computer networks. Educational services; providing of training; entertainment; arranging of sporting and cultural activities; arranging of trade fairs and exhibitions for cultural or educational purposes; production of audiovisual recordings; publication of books and texts, other than publicity texts; provision of on-line electronic publications (not downloadable); arranging and conducting of competitions, colloquiums, conferences and congresses; providing museum facilities (presentation, exhibitions); production and presentation of live performances. Services provided by engineers dealing with appraisals, valuations, research and surveys in the fields of science, technology and design relating thereto; industrial analysis and research services; design and development of computer hardware and software; legal services.
