AN OPTICAL SYSTEM AND A METHOD FOR CHROMATIC CONFOCAL SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY WITH A PLURALITY OF WAVELETS OR FOR CHROMATIC CONFOCAL TWO-BEAM INTERFEROMETRY
The present invention relates to an optical system and a method for chromatic confocal spectral-domain optical coherence tomography or for chromatic confocal two-beam interferometry. The optical system comprises a multispectral light source unit configured to generate a plurality of spatially coherent multispectral light beams with spectra having a respective centroid wavenumbers, an achromatic focusing unit configured such that in at least a paraxial region around a common point located on an optical axis at the output of the achromatic focusing unit, the wavefronts of the respective spatially coherent multispectral light beams have different radii of curvatures, a chromatic confocal dual-beam interferometer having an non-zero optical path difference arranged downstream of the multispectral light source unit and a detection unit for detecting light returned from the dual-beam interferometer. The reference arm of the double-beam interferometer is configured to be achromatic and the object arm to have chromatic depth slitting of foci. In the reference arm, a plurality of depth separated reference light spots are formed. In the object arm, a plurality of at least partially colinear and overlapping multispectral stretches of diffraction limited light spots extended in a depth direction of the object arm is formed. The light reflected by a current sharply focused diffraction limited object light spot of each of the multispectral stretches of diffraction limited light spots is combined with a respective reference light spot, is confocally discriminated by a confocal discrimination unit of the detection unit and subsequently detected by at least one spectrometer, evaluation dual-beam interferometer or fast detector detects the confocally discriminated light.
The present disclosure relates to a tumour necrosis factor receptor 2 (TNFR2) agonist polypeptide comprising (i) a TNFR2 binding domain comprising three TNF homology domains (THD) that specifically bind to TNFR2; and (ii) an Fc domain. The disclosure further relates to a TNFR2 agonist for use in the treatment and/or prevention of - for example - chronic pain or multiple sclerosis.
An aspect of the invention relates to liquid crystal gels (liquid-crystalline gels) exhibiting a ferroelectric nematic liquid-crystalline phase over a substantial range of temperatures, preferably at ambient temperature. The gels are physical gels based on liquid crystal material. In addition, the present invention relates to electric and electronic elements which contain the ferroelectric liquid crystal gels.
C09K 19/02 - Liquid crystal materials characterised by optical, electrical or physical properties of the components, in general
C09K 19/54 - Additives having no specific mesophase
C09K 19/34 - Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
C09K 19/04 - Liquid crystal materials characterised by the chemical structure of the liquid crystal components
C09K 19/20 - Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing at least two benzene rings linked by a chain containing carbon and oxygen atoms as chain links, e.g. esters
The present invention relates to an assembly (1) for an electrically excited machine (100), comprising: a machine rotor (10); an excitation device (6, 7, 20) for electrically exciting the machine (100); and a cooling device (80, 81, 82, 90) for cooling the excitation device. The excitation device comprises an energy transmission system (20), which is integrated in the machine rotor (10) and is designed to contactlessly transmit electrical energy from a primary side (2) of the energy transmission system (20) to a secondary side (4) of the energy transmission system (20), and an electronics device (6, 7). The machine rotor (10) has a machine rotor shaft (13), and the energy transmission system (20) and the electronics device (6, 7) of the excitation device are arranged in a cavity (12) of the machine rotor shaft (13). The cooling device (80, 81, 82, 90) has an inflow channel (80), extending along the longitudinal axis (21) of the energy transmission system (20), for a coolant, and has a plurality of return channels (81, 82), extending in parallel with the longitudinal axis (21) of the energy transmission system (20), for the coolant.
H02K 19/12 - Synchronous motors for multi-phase current characterised by the arrangement of exciting windings, e.g. for self-excitation, compounding or pole-changing
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (Germany)
Universität Stuttgart (Germany)
Inventor
Müller, Theresa
Leistner, Philip
Menges, Achim
Wagner, Hans-Jakob
Abstract
A component for producing building parts has two outer parts arranged at a distance from one another and at least one inner part arranged between the outer parts. The inner part has at least one first part adjacent to an outer part and a second part adjacent to the upper outer part, which has at least one vibration-capable leg, which projects from a third part connecting the first part to the second part, is spaced from the first part by at least one slot and on its side facing away from the first part has at least one recess, which is bridged by the upper outer part and delimited at one end by a projection that has a contact surface, on which the upper outer part is mounted, so that an overall vibration-capable mounting results for the one outer part, leading to a decoupling of structure-borne sound.
E04B 1/74 - Heat, sound or noise insulation, absorption, or reflectionOther building methods affording favourable thermal or acoustical conditions, e.g. accumulating of heat within walls
6.
ONE-STAGE PROCESS FOR CONVERTING CO2 TO ORGANIC MOLECULES BY MEANS OF A COCULTURED MICROBIAL CONSORTIUM
22 to one or more organic molecules selected from the group consisting of cadaverine, glutarate, 5-aminovalerate and mixtures thereof by means of a cocultured microbial consortium in a liquid medium under anaerobic conditions, wherein the microbial consortium comprises acetogenic bacteria and genetically modified Corynebacterium glutamicum.
The present invention pertains to antigen-binding proteins binding to the ligand-binding site of EGFR and to clinically relevant EGFR escape mutations. Specifically, the present invention provides an antigen-binding protein comprising a first antibody variable domain and a second antibody variable domain, wherein the variable domains form a binding site that: specifically binds to a human epidermal growth factor (EGFR) variant having one or more of the mutations V441D, S464L, G465R, and S492R with a KD < 10-5molar determined by biolayer interferometry (BLI); and that does not bind to human EGFR having the mutation Q435P and/or double mutation F436A/I462A with a KD > 10-5 molar determined by biolayer interferometry (BLI). The binding of the antigen-binding protein to human EGFR blocks ligand-induced activation of human EGFR.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
The present invention relates to a method for increasing the productivity of eukaryotic production cells, said production cells expressing one or more protein(s) of interest (POI) during a production phase, comprising the step of irradiating said cells with light having a wavelength or a range of wavelengths within the range of 450 to 500 nm during said production phase.
The invention relates to a quantum computing device comprising at least one atom, wherein the at least one atom has a first electronic state, a second electronic state, and a third electronic state, wherein the third electronic state is a Rydberg electronic state, and an optical capture device configured to emit electromagnetic radiation to capture one or more of the at least one atom, wherein the optical capture device is configured to emit the electromagnetic radiation at a capture wavelength, wherein the first electronic state, the second electronic state, and the Rydberg electronic state have a substantially equal AC polarizability for the capture wavelength. The invention further relates to a use of a quantum computing device and a method for quantum computing.
Embodiments relate to a method, an apparatus, a computer program, a decoder, and a receiver for estimating a polar encoded codeword from a vector, y, of received log-likelihood ratios. The method (10) for estimating a polar encoded codeword from a vector, y, of received log-likelihood ratios comprises obtaining (12) the vector y of received log-likelihood ratios and permuting (14) the vector y to obtain a plurality of permuted versions of the vector y. The method (10) comprises decoding (16) the vector y and the permuted versions of the vector y individually to obtain a decoded codeword estimate and decoded permuted codeword estimates and a path metric per codeword estimate. The method (10) further comprises determining (18) the polar encoded codeword from the decoded codeword estimate and decoded permuted codeword estimates based on the path metric.
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes
11.
APPARATUS AND METHOD FOR CLASSIFYING A METAL POWDER
The invention relates to a method (29) and an apparatus (1) for classifying a metal powder (2). The aim of the invention of improving a characterization and classification of the metal powder (2) is achieved by means of an apparatus (1) which comprises: - an illumination unit (8) for illuminating the metal powder (2), the illumination unit (8) having a plurality of illuminants (10) located around the metal powder (2) so that the metal powder (2) can be illuminated from various horizontal angles and with various light wavelengths; - an image-capturing unit (9) for capturing image data relating to the metal powder (2) illuminated by the illumination unit (8) from the various horizontal angles and the various light wavelengths; and - a processing device (13) for processing the image data, the processing device (13) being operatively connected to the image-capturing unit (9) for signal communication, so that the processing device (13) can classify the metal powder (2) on the basis of the image data transmitted by the image-capturing unit (9).
B22F 10/28 - Powder bed fusion, e.g. selective laser melting [SLM] or electron beam melting [EBM]
B22F 12/90 - Means for process control, e.g. cameras or sensors
B22F 1/052 - Metallic powder characterised by the size or surface area of the particles characterised by a mixture of particles of different sizes or by the particle size distribution
B33Y 40/00 - Auxiliary operations or equipment, e.g. for material handling
B33Y 70/00 - Materials specially adapted for additive manufacturing
G01N 15/00 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/85 - Investigating moving fluids or granular solids
B22F 10/85 - Data acquisition or data processing for controlling or regulating additive manufacturing processes
B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
B22F 10/34 - Process control of powder characteristics, e.g. density, oxidation or flowability
G01N 15/0227 - Investigating particle size or size distribution by optical means using imagingInvestigating particle size or size distribution by optical means using holography
The present invention relates to polypeptide consisting of three TNF homology domains of TNF-ligand family members proteins (THD) that specifically bind to the extracellular part of TNFR2, wherein C-terminal and N-terminal reference points are defined by consensus sequences. The THIDs are linked by short stretches of further C-terminal and/or N-terminal amino acids of the THD or variants thereof as well as by peptide linkers. These peptides have an improved stability. Furthermore the invention relates to polypeptide multimers comprising several of the polypeptides of the present invention.
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (Germany)
Inventor
Meinert, Florian
Ilzhoefer, Philipp
Pfau, Tilman
Traub, Martin
Adams, Martin
Hoffmann, Hans-Dieter
Abstract
The present invention relates to a device (10) for generating optical tweezers comprising a laser beam source (11) for generating a laser beam (12) and at least one acousto-optic deflector (13) for generating an array (15) of partial beams (14) of the laser beam (12), wherein the array (15) comprises rows (15c). The device (10) further comprises a stepped mirror unit (16) comprising at least a first stepped mirror (25) for reducing a row distance (15d) of the partial beams (14) of the array (15), wherein the first stepped mirror (25) comprises mirrors (30), a stepped distance (25a) between adjacent mirrors (30) and a stepped height (25b).
G21K 1/00 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
G21K 1/06 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diffraction, refraction, or reflection, e.g. monochromators
14.
A PUSHER FOR USE IN AN AUTOMATED TEST EQUIPMENT AND METHOD FOR MECHANICALLY PUSHING A DEVICE UNDER TEST INTO A TEST SOCKET
An embodiment according to the invention comprises a pusher (140, 240, 340, 520, 720) for use in an automated test equipment (ATE) to mechanically push a device under test, DUT (110) comprising an antenna or an antenna array into a DUT socket (130). The pusher (140, 240, 340, 520, 720) comprise relatively higher permittivity dielectric regions (160a, 260a, 560a) and relatively lower permittivity dielectric regions (160b, 260b, 560b). The relatively higher permittivity dielectric regions (160a, 260a, 560a) and the relatively lower permittivity dielectric regions (160b, 260b, 560b) are forming a structure of higher permittivity dielectric predominantly parallel columns (160a, 260a, 560a), e.g., rods or pillars or poles, with lower permittivity dielectric regions (160b, 260b, 560b) between these columns. Alternatively, the relatively higher permittivity dielectric regions (160a, 260a, 560a) and the relatively lower permittivity dielectric regions (160b, 260b, 560b) are forming a structure of a higher permittivity dielectric block with lower permittivity dielectric predominantly parallel filled or unfilled holes (160b, 260b, 560b). The higher permittivity dielectric columns (160a, 260a, 560a) or the lower permittivity dielectric holes (160b, 260b, 560b) extend in a first direction(170, 270), which is within ± 45° of a pushing direction (170, 270).
An embodiment according to the invention comprises a pusher (140, 240, 340, 520, 720, 950, 960, 1010, 1110, 1210) for use in an automated test equipment (ATE) to mechanically push a device under test (DUT) (110, 1020, 1150, 1250) comprising an antenna (120, 220, 500, 600, 710, 810, 910) or an antenna array into a DUT socket (130). The pusher (140, 240, 340, 520, 720, 950, 960, 1010, 1110, 1210) comprises a structure (150, 250, 550, 1016, 1120, 1220), in which there are alternating parallel layers (150, 250, 550, 1016, 1120, 1220) of relatively higher dielectric permittivity (160a, 260a, 560a, 1140) and relatively lower dielectric permittivity (160b, 260b, 560b). The layers (150, 250, 550, 1016, 1120, 1220) of higher dielectric permittivity (160a, 260a, 560a, 1140) and lower dielectric permittivity (160b, 260b, 560b) extend in a first direction (170, 270), which is within ± 45° of a pushing direction (170, 270).
The present invention relates to a modular multivalent antigen-binding protein complex, use of the antigen-binding protein complex in medicine and use of the antigen-binding protein complex in the prophylaxis, treatment or diagnosis of a disorder or disease.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (Germany)
Inventor
Qiu, Tian
Fischer, Felix
Gletter, Christian
Abstract
A method for determining a position and an orientation of a localization device, the localization device having a magnet attached to an oscillating element. The method comprises exciting the magnet using one of an external force or torque, resulting in a complex oscillatory motion of the magnet. The said complex motion comprises translation and rotation of the magnetic moment of the magnet about a rotational axis and the rotational axis is located at an offset distance relative to the center of the magnetic moment of the magnet. The method comprises sensing the magnetic field generated by the magnet using at least one sensor. The method comprises determining the position and the orientation of the localization device from the sensing.
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 34/00 - Computer-aided surgeryManipulators or robots specially adapted for use in surgery
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A61B 90/30 - Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
18.
APPARATUS FOR ABSORBING PRECIPITATION WATER AND FOR WATER EVAPORATION
The invention relates to an apparatus for absorbing precipitation water from rain events, especially from driving rain events, and for water discharge by evaporation, wherein at least one textile element for absorbing water from rainwater drops and/or for discharging water by evaporation is provided, wherein the textile element is designed as or embodies a three-dimensional textile structure, with a first, water-permeable layer and a second, water-guiding layer, wherein these layers are connected to one another by means of water-guiding connecting threads, wherein the textile element is preferably fluidically connected via a water discharge conduit to a water collecting device and/or via a water supply conduit to a water supply device.
An interferometer for the measurement of a surface or an optical thickness of an optically smooth test object is provided, wherein the interferometer is configured to illuminate the optically smooth test object simultaneously with a plurality of object waves, which have different wavelengths from one another, and to superimpose the object waves 10 deformed by the illuminated test object onto coherent reference waves on an image capture device, and to spectrally decompose the interferograms resulting from the superposition into wavelength-specific partial interferograms.
The invention relates to an artificial peptide having a length in the range of 10 to 20 amino acids with an amino acid sequence derived from a section of a substrate for a protein lysine methyltransferase, the peptide having a strong binding affinity to protein lysine methyltransferase, the amino acid sequence allowing a loop structure to be formed, and the peptide having inhibitory effect on the enzymatic activity of the protein lysine methyltransferase.
A process for producing an electrical component (1), in particular a sensor such as a gas sensor or a solid oxide fuel cell, is presented. The process comprises: (a) providing a substrate (3), (b) printing a first layer (5) of an ink (7) onto the substrate, wherein the ink comprises a flowable binder and a multiplicity of particles (9) of a metallic, metal-oxide and/or ceramic material that are incorporated in the binder, (c) sintering the substrate including the first layer of ink at a temperature above 300°C, preferably at least 600°C, for a period within a range from 1 min to 1 h, preferably less than 20 min, (d) printing a further layer (11) of an ink onto the substrate, wherein the ink comprises a flowable binder and a multiplicity of particles of a metallic and/or ceramic material that are incorporated in the binder, (e) sintering the substrate including the further layer of ink at a temperature above 300°C for a period within a range from 1 min to 1 h, wherein steps (d) and (e) are repeated multiple times. The combination of ink jet-printed layers and respective sintering of each individual layer in a short and hot sintering operation allows rapid, flexible and cost-effective manufacture of the component.
An ultrasonic system (1) comprises an ultrasonic device (10) having at least one ultrasonic sound head (11) and is configure to record a 3D and/or 4D ultrasonic image of a body part. A frame (20) comprises a movable fastening position (25). The ultrasonic system further comprises at least one encoder (31; 32; 33). The ultrasonic sound head (11) is fastened at the fastening position (25) of the frame (20) in such a manner that it can be moved together with the fastening position (25). The encoder (31; 32; 33) is configured to provide position information about the current position of the movable ultrasonic sound head (11).
A propulsion unit (10) for a spacecraft is described. The propulsion unit (10) comprises a centrally arranged cathode (20), a concentric anode (30), an injection point (60) for injecting a propellant (50) between the central cathode (20) and the concentric anode (30), an acceleration coil system (100) and a vectoring coil system (110) for expelling a plasma plume (75) from a nozzle (115). A plurality of superconducting coils (120, 125) is arranged about the concentric anode (30) for creating a magnetic field (B) between the central cathode (20) and the concentric anode (30) and directing the plasma plume (65) from the nozzle (115).
An optical element (100) is provided comprising a first surface (102) for emitting and/or receiving electromagnetic radiation, the first surface being arranged for optically coupling to, or being optically coupled to, a portion of an optical fibre (104) having an axis. The optical element (100) comprising a second surface (106) positioned for emitting and/or receiving electromagnetic radiation in a direction transversal to the axis of the optical fibre (104), wherein the optical element (100) has a first focal length for electromagnetic radiation emitted and/or received by an inner portion of the second surface (106) and a second focal length for electromagnetic radiation emitted and/or received by an outer portion of the second surface (106), the first and second focal lengths being different focal lengths. A method of forming an optical device comprising the optical element (100) and further comprising an optical fibre coupled to the optical element is also provided.
FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Germany)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Müller, Theresa
Leistner, Philip
Menges, Achim
Wagner, Hans-Jakob
Abstract
A component for producing building parts, such as walls and ceilings, has two outer parts (2, 3) arranged at a distance from one another and at least one inner part (4) arranged between the outer parts (2, 3). The inner part (4) has at least one first part (5) adjacent to an outer part (3) and a second part (6) adjacent to the upper outer part (2), which has at least one vibration-capable leg, which protrudes from a third part connecting the first part (5) to the second part (6), is spaced apart from the first part (5) by at least one slot (7) and on its side facing away from the first part (5) has at least one recess (9), which is bridged by the upper outer part (2) and delimited at one end by a projection that has a contact surface (8), on which the upper outer part (2) is mounted, so that an overall vibration-capable mounting results for the one outer part, which leads to a decoupling of structure-borne noise between the two outer parts (2, 3).
E04B 5/12 - Load-carrying floor structures formed substantially of prefabricated units with wooden beams
E04C 3/12 - JoistsGirders, trusses, or truss-like structures, e.g. prefabricatedLintelsTransoms of wood, e.g. with reinforcements, with tensioning members
26.
CIRCUIT ARRANGEMENT FOR A PLASMA SOURCE FOR GENERATING PLASMA AT ATMOSPHERIC PRESSURE
The invention relates to a circuit arrangement (10) for providing direct current for a plasma source, in particular for generating non-thermal arcs and glow discharges, and a plasma source as well as a method for operating the circuit arrangement (10) and/or the plasma source.
The invention relates to a solid plasma reactor and to methods for operating a fixed bed reactor. According to the invention, they enable the pyrolysis of a wide variety of plastic fractions and organic solids. In addition, lime, for example, can be burned very effectively and without fossil fuels.
C10J 3/00 - Production of gases containing carbon monoxide and hydrogen, e.g. synthesis gas or town gas, from solid carbonaceous materials by partial oxidation processes involving oxygen or steam
28.
PROCESS AND DEVICE FOR OBTAINING CARBON MONOXIDE FROM ATMOSPHERIC CARBON DIOXIDE, USING A SOLID-PLASMA REACTOR
The invention relates to a device (10) for amplifying a laser pulse which comprises a divider section (14) for dividing the laser pulse into multiple sub pulses (43) and for introducing a time delay between the sub pulses (43), a compressor section (15) for compressing the temporally divided sub pulses (43) and a combiner section (17) for combining the compressed sub pulses (44) to one compressed laser pulse (45).
H01S 3/00 - Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
H01S 3/10 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising
30.
MEASUREMENT ARRANGEMENT AND METHOD FOR CHARACTERIZING A RADIO FREQUENCY ARRANGEMENT COMPRISING A PLURALITY OF ANTENNAS
An embodiment according to the present invention is a measurement arrangement for characterizing a radio frequency arrangement (110) comprising a plurality of antennas (120), such as a large array of patch antennas. The measurement arrangement comprises a dielectric waveguide slab (130) with a plurality of frequency converting structures (150), arranged in or on the dielectric waveguide slab. The measurement arrangement further comprises a plurality of waveguide transitions (140) arranged at different positions of the dielectric waveguide slab and are coupled to respective radio frequency components (160). The radio frequency components are configured to transmit and/or receive radio signals (233), like transmitters, receivers or transceivers. The frequency converting structures are associated with respective antennas of the plurality of antennas, and are configured to perform a frequency conversion on signals received, resulting in frequency-converted signals. The frequency converting structures are further configured to couple respective antennas with the dielectric slab in a frequency converting manner, to thereby establish a frequency-converting coupling between the antennas and the plurality of waveguide transitions, resulting in a frequency-converting coupling between the antennas and the radio frequency components. The measurement arrangement is configured to use the frequency-converting coupling between the antennas and the radio frequency components for characterizing the radio frequency arrangement. The radio frequency arrangement can comprise antennas and/or radio frequency frontends connected to the antennas.
The present invention relates to a method for the analogue multiplication and/or calculation of a scalar product, with a circuit assembly, which has a series circuit comprising a first FET and a second FET, or FET array, serving as a current source, a charging device, and a capacitance, which can be precharged by way of the charging device, and can be discharged by way of the series circuit of the first FET and the second FET, or FET array. The capacitance is initially precharged for the multiplication of a first value by a second value. The first value, encoded as the pulse width of a voltage pulse, is applied to the gate of the first FET, and the second value, encoded as the voltage amplitude, is applied to the gate of the second FET. By this means the capacitance is discharged, for the period of time of the voltage pulse, with a discharge current, which is specified by the voltage amplitude applied to the second FET. The result of the multiplication can then be determined from the residual charge or residual voltage of the capacitance. The method operates very energy-efficiently and can advantageously be used for the execution of calculations in neurons of an artificial neural network.
G06F 7/544 - Methods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using non-contact-making devices, e.g. tube, solid state deviceMethods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using unspecified devices for evaluating functions by calculation
H03M 1/82 - Digital/analogue converters with intermediate conversion to time interval
A plasma thruster comprises a cylindrical discharge channel (1), an injector (4), a RF antenna surrounding the discharge channel (1) and a device (3) for generating an axial static magnetic field in the discharge channel (1). The RF antenna is a cylindrical birdcage antenna (2) formed of several electrically conductive parallel legs (10) connected by two end rings (11) including capacitors (12) between adjacent legs (10) in each case. The two end rings (11) with the capacitors (12) are formed on two printed circuit boards (14) to which the legs (10) are attached, said printed circuit boards (14) having a through opening for the discharge channel (1). The antenna maximizes electrical coupling efficiency and provides resulting electromagnetic fields for quasi-neutral plasma acceleration along with the magnetic field effect provided by the externally applied magnetic field. This plasma thruster allows an easy upscaling or downscaling due to the printed circuit boards and is particularly suitable for low power applications like propulsion for smaller spacecrafts or satellites.
A cell (110) for carrying out quantum optical measurements on at least one atom cloud is proposed. The cell (110) comprises a control unit (114) for controlling electric fields at the location (112) of the atom cloud. The control unit (114) comprises:
at least one housing (116) having at least one interior (120) for receiving the atom cloud and having at least one opening (122) for introducing the atoms of the atom cloud into the interior (120); and
at least two electrodes (118),
wherein the electrodes (118), independently of one another, are able to be subjected to electrical potentials and are configured to influence at least one electric field in the interior (120),
wherein the electrodes (118) are mechanically connected to the housing (116).
A cell (110) for carrying out quantum optical measurements on at least one atom cloud is proposed. The cell (110) comprises a control unit (114) for controlling electric fields at the location (112) of the atom cloud. The control unit (114) comprises:
at least one housing (116) having at least one interior (120) for receiving the atom cloud and having at least one opening (122) for introducing the atoms of the atom cloud into the interior (120); and
at least two electrodes (118),
wherein the electrodes (118), independently of one another, are able to be subjected to electrical potentials and are configured to influence at least one electric field in the interior (120),
wherein the electrodes (118) are mechanically connected to the housing (116).
At least one of the electrodes (118) is at least partly formed by at least one optical window (130) through which at least one light beam (132) for interaction with the atom cloud is able to be radiated into the interior (120). The optical window (130) comprises at least one transparent substrate (134) and at least one transparent electrically conductive coating (136) of the substrate (134). Furthermore, a system (182) for carrying out quantum optical measurements on at least one atom cloud, a quantum computer (204) and a method for carrying out quantum optical measurements on at least one atom cloud are proposed.
An imaging device and method for imaging an object, such as for multispectral or hyperspectral imaging, are disclosed. The imaging device includes an image sensor located in an image plane of the imaging device. The image sensor includes photosensitive elements. A first imaging system is configured to generate an intermediate image of the object in an intermediate image plane. A second imaging system is configured to generate an image of the intermediate image on the image sensor in the image plane. A diffractive optical element is arranged in the intermediate image plane. An aperture is arranged in a beam path of the second imaging system between the intermediate image plane and the image sensor. The diffractive optical element, the second imaging system, and the aperture are arranged such that different images for different wavelengths of the intermediate image are generated on different groups of the photosensitive elements.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01J 3/18 - Generating the spectrumMonochromators using diffraction elements, e.g. grating
H04N 23/45 - Cameras or camera modules comprising electronic image sensorsControl thereof for generating image signals from two or more image sensors being of different type or operating in different modes, e.g. with a CMOS sensor for moving images in combination with a charge-coupled device [CCD] for still images
35.
METHOD FOR AUTOMATEDLY DETERMINING EXPOSURE PATTERNS
A computer-implemented method for automatedly determining exposure patterns for the layer-by-layer manufacture of at least one component from a CAD model of the component in an additive powder bed method is proposed. The method comprises the following steps: a) cutting the CAD model into a finite number of layers (122); b) determining at least one exposure path (124) for each layer (122), the exposure path (124) having beam position data for the control of an exposure beam (126) in the additive powder bed method, determining the exposure path (124) comprising: i) creating and solving a partial differential equation and/or a functional and/or an eigenvalue problem, comprising discretizing the layer (122), at least one boundary condition being allocated to an edge (128) of the layer (122), and generating at least one solution function (130); ii) determining the exposure path (124) from the solution function (130), at least one property of the additive powder bed method being taken into account; c) determining at least one exposure pattern from the exposure paths (124) of the layers (122). A computer program for carrying out the computer-implemented method, a method for manufacturing at least one component in an additive powder bed method by means of at least one automatedly determined exposure pattern, a calculation device (142) for automatedly determining exposure patterns, and a manufacturing device (154) for the layer-by-layer manufacture of at least one component in an additive powder bed method by means of at least one automatedly determined exposure pattern are furthermore proposed.
An input apparatus for operating and/or controlling a technical device includes a plurality of sensor elements which can be arranged spatially distributed in the oral cavity of a user. An interface circuit is coupled to the sensor elements and is configured to detect a respective current tongue position and/or tongue movement by means of the sensor elements. The interface circuit generates one or more control signals depending on the respective current tongue position and/or tongue movement and transmits the one or more control signals to the technical device. Advantageously, the sensor elements each include a transponder which is configured to receive an interrogation signal from the interface circuit and, in response thereto, to transmit an individually coded response signal to the interface circuit.
The invention relates to a cooling method using a heat exchanger (1), the method being intended to cool a first fluid by means of a second fluid, in which method the first fluid leaves and enters the heat exchanger (1) repeatedly so as to exchange heat with itself and with the second fluid, by indirect contact.
F28D 7/00 - Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
F28D 9/00 - Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
F28B 1/02 - Condensers in which the steam or vapour is separated from the cooling medium by walls, e.g. surface condenser using water or other liquid as the cooling medium
38.
STRUCTURAL TRANSPARENT FIBER-MATRIX COMPOSITES AND PROCESS FOR PRODUCTION THEREOF
The invention relates to transparent and especially structural transparent fiber-matrix composites formed from a polymeric matrix and transparent reinforcing fibers, wherein the refractive index of the polymeric matrix is matched to that of the reinforcing fibers. The invention further relates to processes for producing such transparent and structural transparent fiber-matrix composites by infusion processes, to processes for producing fiber-matrix composite hybrid yarns and correspondingly produced hybrid yarns, and to the use of the fiber-matrix composites as described in structural transparent panes that may exhibit ballistic protection.
The present invention relates to a measuring device (10) and a method for determining a depth of field of an optical structure (100). In this case, the measuring device comprises a device body (12) with a measuring axis (14), the device body (12) being formed such that, in a measuring position, it can be placed in a stationary manner on a deposit plane of the optical structure such that the measuring axis (14) of the device body (12) coincides with an optical axis of the optical structure, wherein the device body (12) has a measurement scale (18) arranged along a scale line (16) such that the scale line (16) encloses with the direction of the measuring axis (14) a scale angle φ greater than 0° and less than 90° and the measurement scale (18) can be optically detected in the measuring position of the device body (12) by the optical structure (100) for determining the depth of field.
G01B 11/22 - Measuring arrangements characterised by the use of optical techniques for measuring depth
G01F 15/00 - Details of, or accessories for, apparatus of groups insofar as such details or appliances are not adapted to particular types of such apparatus
The invention relates to a radiation field provision device, in which in particular an optical path for a radiation field is defined, comprising a frequency conversion body, the frequency conversion body being partially formed by a frequency-converting medium and a reflector.
The present invention relates to a trivalent binding molecule comprising a first polypeptide comprising two binding domains and a second polypeptide comprising a third binding domain. The present invention further relates to the trivalent binding molecule for use in medicine and in particular in the prophylaxis, treatment or diagnosis of a disorder or disease.
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
The present invention relates to binding molecules comprising two polypeptide chains, wherein the peptide chains comprise modified EHD2 domains allowing heterodimerization only, thereby preventing homodimers, nucleic acids encoding such binding molecules and uses of such binding molecules or nucleic acids encoding such binding molecules in therapy.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
A method for improving time planning in time-critical networks is proposed. This is done by means of a computer network with a plurality of network users. To carry out the method, all network users along a transmission path from a network user functioning as a transmitter to a network user functioning as a receiver are first detected. Once these network users are known, the longest possible transfer time for a data stream between any two network users along the transmission path is calculated according to an interference model or an end-to-end model. The longest possible transfer time between a transmitter and a receiver is then calculated by summing the calculated transfer times. This transfer time between the transmitter and the receiver that is calculated in this way can then be taken as a basis for the time planning in the network.
The present invention relates to polypeptide consisting of three TNF homology domains of TNF-ligand family members proteins (THD) that specifically bind to the extracellular part of TNFR2, wherein C-terminal and N-terminal reference points are defined by consensus sequences. The THDs are linked by short stretches of further C-terminal and/or N-terminal amino acids of the THD or variants thereof as well as by peptide linkers. These peptides have an improved stability. Furthermore the invention relates to polypeptide multimers comprising several of the polypeptides of the present invention.
DETERMINING AN ACTUAL VALUE AND/OR AN ACTUAL VALUE RANGE OF AT LEAST ONE STATE VARIABLE OF A FLUID IN A FLUID FLOW BY MEANS OF AT LEAST ONE INDICATOR PARTICLE
The invention relates to a method for determining an actual value and/or an actual value range of at least one state variable of a fluid in a fluid flow by means of at least one indicator particle (9) introduced into the fluid. In addition it is proposed that the at least one indicator particle (9) is designed and provided for an irreversible property change of an indicator property of the indicator particle (9) in the case of a certain indicator value of the at least one state variable in the fluid flow and/or as a clear function of the actual value when a certain period of time has elapsed after the indicator particle (9) has been introduced into the fluid, wherein the indicator particle (9) is detected at a detection point, the indicator property of the indicator particle (9) is evaluated and the actual value and/or the actual value range of the state variable is inferred from the indicator property upstream of the detection point. The invention also relates to a method for operating a fluid-guiding device (7), an indicator particle (9) and a device (7) for determining the actual value and/or actual value range of the at least one state variable.
G01L 23/00 - Devices or apparatus for measuring or indicating or recording rapid changes, such as oscillations, in the pressure of steam, gas, or liquidIndicators for determining work or energy of steam, internal-combustion, or other fluid-pressure engines from the condition of the working fluid
46.
HEAT EXCHANGER, HEAT EXCHANGER NETWORK, HEAT EXCHANGER METHOD, AND EXTERNAL HEAT TRANSFER DEVICE
The invention relates to a heat exchanger, comprising: a first refrigerant network portion, through which a first refrigerant flows, the first refrigerant network portion having a first heat exchanger inflow portion and a first heat exchanger outflow portion; a second refrigerant network portion, through which a second refrigerant flows, the second refrigerant network portion having a second heat exchanger inflow portion and a second heat exchanger outflow portion, the heat exchanger being designed to transfer, in a heat exchange portion, thermal energy between the first refrigerant network portion and the second refrigerant network portion; and at least one external heat transfer device, each external heat transfer device being coupled thermally, at least partially, to the first heat exchanger inflow portion or the first heat exchanger outflow portion, each external heat transfer device also being coupled thermally, at least partially, to the second heat exchanger inflow portion or the second heat exchanger outflow portion, each external heat transfer device being designed to transfer thermal energy between the first refrigerant network portion and the second refrigerant network portion. The invention further relates to heat exchanger networks, heat exchange methods and external heat transfer devices.
F25B 25/00 - Machines, plants or systems, using a combination of modes of operation covered by two or more of the groups
F28D 9/00 - Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
The invention relates to a quantum computing device comprising at least one atom, wherein the at least one atom has a first electronic state, a second electronic state, and a third electronic state, wherein the third electronic state is a Rydberg electronic state, and an optical capture device configured to emit electromagnetic radiation to capture one or more of the at least one atom, wherein the optical capture device is configured to emit the electromagnetic radiation at a capture wavelength, wherein the first electronic state, the second electronic state, and the Rydberg electronic state have a substantially equal AC polarizability for the capture wavelength. The invention further relates to a use of a quantum computing device and a method for quantum computing.
Presented is an interferometer (10) for the extensive measurement of a surface (108) or optical thickness of an optically smooth test object (122), the interferometer (10) being configured to simultaneously illuminate the optically smooth test object with a plurality of object waves (14.1, 14.2, 14.3) which have different wavelengths from one another, to superpose the object waves deformed by the illuminated test object with coherent reference waves on an image recorder (K) and to spectrally decompose interferograms emerging from the superposition into wavelength-individual partial interferograms.
Enzyme mutant with squalene-hopene-cyclase activity, selected from mutants of a wild-type enzyme comprising an amino acid sequence selected from SEQ-ID No: 1 to 3 or an amino acid sequence derived therefrom with a degree of sequence identity in the range of from 60 to 99,9 % of SEQ-ID No. 1 to 3, wherein the mutant catalyzes a one-step monocyclization reaction to produce products such as gamma-dihydroionone and/or alpha-dihydroionone.
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (Germany)
Universität Stuttgart (Germany)
Inventor
Derwenskus, Felix
Schmid-Staiger, Ulrike
Bringmann, Christian
Abstract
The invention relates to methods for obtaining a fucoxanthin-crystal-containing precipitate, in particular fucoxanthin crystals, in particular fucoxanthin, and a fatty-acid-containing lipid fraction, in particular fatty acids, from the biomass of algae, in particular methods for the integrated extraction and separation of fucoxanthin and fatty acids from the biomass of algae, and to the products obtained from these methods, in particular fucoxanthin crystals and fatty acids.
C07D 303/32 - Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
C07C 51/43 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation
A propulsion unit (10) for a spacecraft is described. The propulsion unit (10) comprises a centrally arranged cathode (20), a concentric anode (30), an injection point (60) for injecting a propellant (50) between the central cathode (20) and the concentric anode (30), an acceleration coil system (100) and a vectoring coil system (110) for expelling a plasma plume (75) from a nozzle (115). A plurality of superconducting coils (120, 125) is arranged about the concentric anode (30) for creating a magnetic field (B) between the central cathode (20) and the concentric anode (30) and directing the plasma plume (65) from the nozzle (115).
The invention relates to an apparatus (10) for absorbing precipitation water from rain events, especially from driving rain events, and for water discharge by evaporation, wherein at least one textile element (12) for absorbing water from rainwater drops and/or for discharging water by evaporation is provided, wherein the textile element (12) is designed as or embodies a three-dimensional textile structure (13), with a first, water-permeable layer (14) and a second, water- guiding layer (16), wherein these layers (14, 16) are connected to one another by means of water-guiding connecting threads (18), wherein the textile element (12) is preferably fluidically connected via a water discharge conduit (20) to a water collecting device (24) and/or via a water supply conduit (22) to a water supply device (26, 67). The invention relates also to a facade system (100) for separating a building interior (inside) I from an exterior space (outside) 0 comprising such apparatus (10) is specified, wherein the facade system (100) is optionally constructed in one or more layers (104, 106, 108, 110) and/or modularly, with or without at least one fluid- flow-through layer (104, 108) with or without an insulation layer (106) with or without an inner layer (110), wherein these components of the facade system (100) and/or the holding device and/or the frame profile (34, 34') of the apparatus (10) are preferably attached of attachable to a modular profile system (102, 102').
E03B 1/04 - Methods or layout of installations for water supply for domestic or like local supply
A01G 9/02 - Receptacles, e.g. flower-pots or boxes Glasses for cultivating flowers
E03B 3/02 - Methods or installations for obtaining or collecting drinking water or tap water from rain-water
E04C 1/39 - Building elements of block or other shape for the construction of parts of buildings characterised by special adaptations, e.g. serving for locating conduits, for forming soffits, cornices, or shelves, for fixing wall-plates or door-frames, for claustra
53.
Combination of Resolver and Inductive Rotor Supply in One Magnetic Circuit
The invention relates to a device for the contactless transfer of electric power to a load arranged on a rotor 20 of an electric machine and for detecting the angular position of the rotor 20. The device comprises an inductive power transfer path for the inductive transfer of electric power to the electrical load and a resolver for detecting an angular position of the rotor 20, wherein the inductive power transfer path and the resolver use one magnetic circuit.
The invention relates to a device for the contactless transfer of electric power to a load arranged on a rotor 20 of an electric machine and for detecting the angular position of the rotor 20. The device comprises an inductive power transfer path for the inductive transfer of electric power to the electrical load and a resolver for detecting an angular position of the rotor 20, wherein the inductive power transfer path and the resolver use one magnetic circuit.
The invention furthermore relates to a corresponding method and to a corresponding electric machine.
The invention relates to a seal (1), comprising a sealing side (2), a back side (3) and at least one sealing body (8), wherein a longitudinal extent of the sealing body (8) is in the same direction as the sealing side (2) and the rear side (3). According to the invention, the sealing body (8) has at least one through-flow element (9) having at least one through-flow opening (9a), through which through-flow element an outflow medium (10) can flow out of the sealing body (8) and/or a medium can be sucked into the sealing body (8), the at least one through-flow opening (9a) being formed in only a portion of the longitudinal extent of the sealing body (8), and the at least one through-flow opening (9a) being located on an outside contour of the sealing body (8).
The present invention relates to a circuit arrangement having an active rectifier circuit, in particular on a secondary side of an inductive energy transmission path. The circuit arrangement has a half or full bridge of power transistors for rectifying an AC voltage induced in an input inductor of the circuit arrangement. The power transistors are connected to the input inductor in such a way that an auxiliary voltage is split off from the induced AC voltage for switching the power transistors. As a result, even large currents, which result in a low output voltage, can be transmitted without endangering the operation of the rectifier circuit.
H02J 50/10 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
H02M 7/217 - Conversion of AC power input into DC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only
H02P 9/12 - Control effected upon generator excitation circuit to reduce harmful effects of overloads or transients, e.g. sudden application of load, sudden removal of load, sudden change of load for demagnetisingControl effected upon generator excitation circuit to reduce harmful effects of overloads or transients, e.g. sudden application of load, sudden removal of load, sudden change of load for reducing effects of remanenceControl effected upon generator excitation circuit to reduce harmful effects of overloads or transients, e.g. sudden application of load, sudden removal of load, sudden change of load for preventing pole reversal
In a method and an apparatus for detecting electrically conductive foreign bodies during inductive energy transmission between a primary coil (1) and a secondary coil (2), at least one sensor coil (5) is arranged between the primary coil (1) and the secondary coil (2), and a current flowing in the sensor coil (5) due to the induced voltage during the energy transmission is detected and evaluated. In this case, the sensor coil (5) is connected to at least one capacitor to form a resonant circuit which is matched to the excitation frequency of the primary coil (1). The phase position of the current in the resonant circuit in relation to a reference signal is then used to determine whether there are electrically conductive foreign bodies (4) between the primary coil (1) and the secondary coil (2). A high degree of sensitivity, also in relation to small electrically conductive foreign bodies within the energy transmission path, is achieved by means of the method and the apparatus.
H02J 50/60 - Circuit arrangements or systems for wireless supply or distribution of electric power responsive to the presence of foreign objects, e.g. detection of living beings
H02J 50/10 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
B60L 53/124 - Detection or removal of foreign bodies
H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
An optical element (100) is provided comprising a first surface (102) for emitting and/or receiving electromagnetic radiation, the first surface being arranged for optically coupling to, or being optically coupled to, a portion of an optical fibre (104) having an axis. The optical element (100) comprising a second surface (106) positioned for emitting and/or receiving electromagnetic radiation in a direction transversal to the axis of the optical fibre (104), wherein the optical element (100) has a first focal length for electromagnetic radiation emitted and/or received by an inner portion of the second surface (106) and a second focal length for electromagnetic radiation emitted and/or received by an outer portion of the second surface (106), the first and second focal lengths being different focal lengths. A method of forming an optical device comprising the optical element (100) and further comprising an optical fibre coupled to the optical element is also provided.
arranging an additional electrically conductive material layer (13) on at least one active part (12, 19, 35, 45) of the energy transfer device (100), wherein an active part of the energy transfer device (100) is a part of the energy transfer device (100) which is at least partially exposed to the magnetic field used for energy transfer, and wherein the electrical conductivity of the additional material layer (13) is greater than the electrical conductivity of the at least one active part (12, 19, 35, 45).
Moreover, the invention relates to an energy transfer device (100) and to a use of an electrically conductive material.
H02K 11/00 - Structural association of dynamo-electric machines with electric components or with devices for shielding, monitoring or protection
H02K 5/20 - Casings or enclosures characterised by the shape, form or construction thereof with channels or ducts for flow of cooling medium
H02K 7/00 - Arrangements for handling mechanical energy structurally associated with dynamo-electric machines, e.g. structural association with mechanical driving motors or auxiliary dynamo-electric machines
H02K 11/30 - Structural association with control circuits or drive circuits
H02J 50/10 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
H02K 3/04 - Windings characterised by the conductor shape, form or construction, e.g. with bar conductors
H02K 9/00 - Arrangements for cooling or ventilating
59.
Tumor necrosis factor receptor (TNFR) binding protein complex with improved binding and bioactivity
The present invention relates to a tumor necrosis factor receptor (TNFR) binding protein complex comprising 12 or more N protein ligands (PLs) that specifically bind to the extracellular part of the same TNFR. Preferably, the TNFR binding protein complex binds to the extracellular part of TNFR2. Preferably, the TNFR binding protein complex of the present invention further comprises a two or more polymerization domains (PD).
The invention relates to an input device for operating and/or controlling a technical device (26, 28), said input device comprising a plurality of sensor elements (18) which can be spatially distributed in the oral cavity (12) of a user. An interface circuit (20) is coupled to the sensor elements (18) and designed to detect a current tongue position and/or tongue movement using the sensor elements (18). In accordance with the current tongue position and/or tongue movement, the interface circuit (20) generates a plurality of control signals and transmits these to the technical device (26, 28). Advantageously, the sensor elements (18) include a respective transponder, which is designed to receive a request signal (30) and, according to same, to transmit a individually encoded response signal (32, 34) to the interface circuit (20). Advantageously, the interface circuit (20) is designed to generate the request signal (30).
FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Germany)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Du, Nan
Schmidt, Heidemarie
Schulz, Stefan
Polian, Ilia
Xianyue, Zhao
Abstract
The invention relates to a device for generating a sequence of random numbers in accordance with an embodiment. The device comprises a switchable element (110), which can be switched into a first state by application of a first bias voltage, and which can be switched into a second state by application of a second bias voltage, which is different from the first bias voltage. The switchable element (110) is designed, when switched by the first bias voltage into the first state, to output a first output voltage with a first random or pseudorandom voltage value from a first voltage value range. The switchable element (110) is also designed, when switched by the second bias voltage into the second state, to output a second output voltage with a second random or pseudorandom voltage value from a second voltage value range. Furthermore, the device comprises a comparator which is designed to output a first number value when the first output voltage from the first value range is smaller than or equal to a first limit voltage; and to output a second number value, which is different from the first number value, when the first output voltage from the first value range is greater than the first limit voltage. The comparator is also designed to output the first number value when the second output voltage from the second value range is smaller than or equal to a second limit voltage, and to output the second number value when the second output voltage from the second value range is greater than the second limit voltage. Or, otherwise, the comparator is designed to output the second number value when the second output voltage from the second value range is smaller than or equal to a second limit voltage, and to output the first number value when the second output voltage from the second value range is greater than the second limit voltage.
FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Germany)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Du, Nan
Schmidt, Heidemarie
Schulz, Stefan
Polian, Ilia
Bürger, Danilo
Abstract
The invention relates to a device comprising two or more switchable elements (111, 112) for generating a binary number sequence. A first write voltage or a second write voltage, differing from the first, and/or a first read voltage or a second read voltage, differing from the first, is applied to each of the switchable elements (111, 112). Each switchable element (111, 112) is designed to output, dependent on the write voltage and/or read voltage applied, an output voltage with a first or second (pseudo-)random voltage value respectively from a first or second voltage value range respectively. The device additionally comprises one or more comparators (121) associated with precisely one of the switchable elements. Each comparator (121) is designed to output a binary output value depending on a comparison of the output voltage of the switchable element (111, 112) associated with the comparator with a limit voltage. The device is designed to generate the binary number sequence dependent on the binary output value of each comparator (121).
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
63.
METHOD FOR THE ANALOGUE MULTIPLICATION AND/OR CALCULATION OF A SCALAR PRODUCT WITH A CIRCUIT ASSEMBLY, IN PARTICULAR FOR ARTIFICIAL NEURAL NETWORKS
The invention relates to a method for the analogue multiplication and/or calculation of a scalar product with a circuit assembly, which has a series circuit formed by a first FET and a second FET or FET array functioning as a power source, a charging device and a capacitor, which can be precharged via the charging device and can be discharged via the series circuit formed by the first FET and the second FET or FET array. The capacitor is initially precharged for the multiplication of a first value with a second value. The first value is applied at the gate of the first FET as the pulse length of a voltage pulse and in an encoded manner, and the second value is applied at the gate of the second FET as the voltage amplitude and in an encoded manner. In this way, the capacitor is discharged for the period of the voltage pulse with a discharge current, which is specified by the voltage amplitude applied at the second FET. The result of the multiplication can then be determined from the residual charge or residual voltage of the capacitor. The method is very energy efficient and can be used advantageously for carrying out calculations in neurones of an artificial neural network.
G06G 7/16 - Arrangements for performing computing operations, e.g. amplifiers specially adapted therefor for multiplication or division
G06N 3/063 - Physical realisation, i.e. hardware implementation of neural networks, neurons or parts of neurons using electronic means
G06G 7/161 - Arrangements for performing computing operations, e.g. amplifiers specially adapted therefor for multiplication or division with pulse modulation, e.g. modulation of amplitude, width, frequency, phase, or form
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof
C08J 9/30 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by mixing gases into liquid compositions or plastisols, e.g. frothing with air
65.
APPARATUS FOR COUPLING LIGHT INTO AN OPTICAL FIBER
UNIVERSITÀ DEGLI STUDI DEL SANNIO DI BENEVENTO (Italy)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Portalupi, Simone Luca
Michler, Peter
Jetter, Michael
Witz, Norbert
Cusano, Andrea
Cutolo, Antonello
Micco, Alberto
Ricciardi, Armando
Abstract
The present invention is directed to arrangement for coupling and/or receiving light into/from an optical fiber core and to method of manufacturing said arrangement. The arrangement comprises an optical fiber having at least one optical fiber core, an optical fiber coating (22) at one end of the optical fiber partially and/or completely overlapping the fiber end and having a central opening at its end facet exposing the fiber core, the optical fiber coating (22) consisting of an electrically conductive material or is covered with an electrically conductive material, and an opto-electronic device (20) at the facet of the optical fiber coating (22) for coupling and/or receiving light into/from the fiber core and the opto-electronic device (20) being coupled to the optical fiber coating (22) and covers the central opening of the optical fiber coating. According to the invention the opto-electronic device (20) is directly and electrically coupled to the end facet of the optical fiber coating (22).
Fourier Transformation Spectrometer, FT Spectrometer, comprising: Michelson-Type Interferometer (601, 602, 603, 604, 605, 606, 607, 608, 609) comprising: at least one beam splitter unit designed to split an incident light beam (EB) of a spatially expanded object into a first partial beam (TB1) and a second partial beam (TB2); and for at least partially overlaying the first partial beam (TB1) and the second partial beam (TB2) with a lateral shear (s); a first beam deflection unit designed to deflect the first partial beam (TB1) at least once; a second beam deflection unit designed to deflect the second partial beam (TB2) at least once; wherein at least one among the first beam deflection unit and the second beam deflection unit represents a (2n+1) periscope group with (2n+1) mirror surfaces, and all (2n+1) mirror surfaces are arranged vertically in relation to a common reference plane, in order to respectively deflect the first partial beam (TB1) and/or the second partial beam (TB2) (2n+1) times, and wherein the (2n+1)-fold deflection generates the lateral shear (s) between the first partial beam (TB1) and the second partial beam (TB2), and wherein n is a natural number ≥1.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G01N 21/45 - RefractivityPhase-affecting properties, e.g. optical path length using interferometric methodsRefractivityPhase-affecting properties, e.g. optical path length using Schlieren methods
67.
NETWORK OF METAL FIBERS, METHOD FOR PRODUCING A NETWORK OF METAL FIBERS, ELECTRODE AND BATTERY
Max-Planck-Gessellschaft zur Förderung der Wissenchaften E.V. (Germany)
Universität Stuttgart (Germany)
Inventor
Hackner, Maximilian
Jahnke, Timotheus
Burghard, Zaklina
Micoulet, Alexandre
Spatz, Joachim P.
Möller, Martin
Abstract
The present invention relates to a network of metal fibers, comprising a plurality of metal fibers fixed to one another; wherein at least some of the plurality of metal fibers have a length of 1.0 mm or more, a width of 100 μm or less and a thickness of 50 μm or less. The invention further relates to a method comprising step 1 of producing a plurality of metal fibers (2) by melt spinning; step 2 of providing a loose network of metal fibers (2) produced in step 1; and step 3 of fixating the plurality of metal fibers to one another by one of the following processes c1 to c4.
H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
B22F 9/10 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from liquid material by casting, e.g. through sieves or in water, by atomising or spraying using centrifugal force
B22F 1/00 - Metallic powderTreatment of metallic powder, e.g. to facilitate working or to improve properties
B22F 3/14 - Both compacting and sintering simultaneously
B22F 1/02 - Special treatment of metallic powder, e.g. to facilitate working, to improve properties; Metallic powders per se, e.g. mixtures of particles of different composition comprising coating of the powder
C22C 9/02 - Alloys based on copper with tin as the next major constituent
C22C 19/07 - Alloys based on nickel or cobalt based on cobalt
68.
REACTOR CONCEPT AND PROCESS FOR PREPARING ETHYLENE OXIDE FROM ETHANOL
The invention relates to a catalyst arrangement for preparation of ethylene oxide from ethanol, comprising a first catalyst [1] which is suitable for dehydration of ethanol to ethylene and is in direct fluid connection to a second catalyst [2] suitable for oxidation of ethylene to ethylene oxide with oxygen, characterized in that at least the first catalyst [1] is configured as a fixed catalyst bed. The invention also relates to a process for preparing ethylene oxide from ethanol, wherein a gas stream comprising oxygen and ethanol is guided through the catalyst arrangement according to the invention in order to obtain a product gas stream.
C07D 301/08 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with air or molecular oxygen in the gaseous phase
The invention relates to a catalyst arrangement for preparation of ethylene oxide from ethanol, comprising a first catalyst which is suitable for dehydration of ethanol to ethylene and is in fluid connection to a second catalyst suitable for oxidation of ethylene to ethylene oxide with oxygen, characterized in that the first catalyst is an acidic catalyst having an overall density of acidic sites of more than 1 µmol/m2. The invention also relates to a process for preparing ethylene oxide from ethanol, comprising the steps of: a) contacting ethanol with a first catalyst suitable for dehydration of ethanol to ethylene to obtain ethylene, b) contacting the ethylene from step a) with a second catalyst suitable for oxidation of ethylene to ethylene oxide with oxygen, characterized in that the first catalyst is an acidic catalyst having an overall density of acidic sites of more than 1 µmol/m222 support.
C07C 1/24 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as hetero atoms by elimination of water
C07D 301/10 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with air or molecular oxygen in the gaseous phase with catalysts containing silver or gold
16 - Paper, cardboard and goods made from these materials
25 - Clothing; footwear; headgear
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Decoration and art materials and media; Printed matter, and stationery and educational supplies; Tear-off calendars; Transfers [decalcomanias]; Address books; Address plates; Address labels; File covers; Folders for papers; Document files [stationery]; Index files; Almanacs; General feature magazines; Souvenir programmes; Instruction sheets; Announcement cards [stationery]; Pop-up greetings cards; Stickers [decalcomanias]; Vehicle bumper stickers; Stickers [stationery]; Display binders; Display banners made of cardboard; Badge holders [office requisites]; Badge holders of plastic [office requisites]; Automatic adhesive dispensers for office use; Automatic adhesive tape dispensers for office use; Banners of paper; Architectural plans; Computer software operating manuals; Printed transfers for embroidery or fabric appliqués; Printed flip charts; Printed cards; Printed advertising boards of paper; Printed advertising boards of cardboard; Adhesive printed labels; Manuals for instructional purposes; Computer hardware users guide; Paper report covers; Order forms; Pouches for writing instruments; Picture postcards; Blank cards; White papers; Blank forms; Pads [stationery]; Classified directories; Notepaper; Writing paper; Pamphlets; Office paper stationery; Works of art and figurines of paper and cardboard, and architects' models; Paper and cardboard; Bags and articles for packaging, wrapping and storage of paper, cardboard or plastics; Educational equipment; 3D decals for use on any surface; Printed educational materials; Address lists; Paper sheets [stationery]; Recycled bond paper; Signboards of paper or cardboard; Note pads; Paper; Clips for name badge holders [office requisites]; Thank you cards; Document holders [stationery]; File pockets for stationery use; Printed matter for instructional purposes; Document covers; Labels of paper or cardboard; Professional magazines; Forms, printed; Printed reports; Printed brochures; Printed leaflets; Printed research reports; Printed manuals; Printed information sheets; Printed informational cards; Printed informational folders; Printed calendars; Printed curricula; Printed guides; Printed plans; Printed training materials; Printed seminar notes; Printed lessons; Printed lectures; Printed periodicals; Printed visuals; Printed teaching materials; Adhesive note pads; Envelopes [stationery]; Paper folders; Informational sheets; Informational letters; Information booklets; Calendars; Catalogues; Paper book markers; Rulers; Monthly planners; Paper name badges; Files [office requisites]; Posters; Posters made of paper; Prospectuses; Newsletters; Writing tablets; Writing stationery; Pocket calendars; Visiting cards; Wall planners. Clothing; Tee-shirts; Sweat shirts. Education, entertainment and sport services; Education, entertainment and sports. Science and technology services; Design services; Testing, authentication and quality control.
A method and a device for testing, the device comprising a learning arrangement adapted to provide scenarios for test cases and principles to be tested, in particular comprising a digital representation of one or more of a law, an accident report, a log, or human expertise or a combination thereof, wherein the learning arrangement is adapted to determine at least one rule for test case generation from the scenarios and the principles, and wherein a modelling arrangement is adapted to determine, store and/or output a model for test case generation depending on the at least one rule. A method and a device for testing an at least partially autonomous apparatus or a behavior of a user at an at least partially autonomous apparatus, including a selecting arrangement adapted to determine a scenario for testing depending on a probability defined for the scenario in a probability distribution, and to determine a test case depending on the scenario and depending on information about the at least partial autonomous apparatus, and a testing arrangement adapted to determine an output for the at least partially autonomous apparatus depending on the test case, detect a response to the test case at the at least partially autonomous apparatus and to determine a result of the testing depending on the response.
A method and a device for testing, the device including a learning arrangement adapted to provide scenarios for test cases and principles to be tested, in particular comprising a digital representation of one or more of a law, an accident report, a log, or human expertise or a combination thereof, wherein the learning arrangement is adapted to determine at least one rule for test case generation from the scenarios and the principles, and wherein a modelling arrangement is adapted to determine, store and/or output a model for test case generation depending on the at least one rule.
G06N 20/10 - Machine learning using kernel methods, e.g. support vector machines [SVM]
G06K 9/62 - Methods or arrangements for recognition using electronic means
73.
CATION EXCHANGE POLYMERS AND ANION EXCHANGE POLYMERS AND CORRESPONDING (BLEND) MEMBRANES MADE OF POLYMERS CONTAINING HIGHLY FLUORINATED AROMATIC GROUPS, BY WAY OF NUCLEOPHILIC SUBSTITUTION
The present invention relates to new anion exchange polymers and corresponding (blend) membranes made of polymers containing highly fluorinated groups, by way of nucleophilic substitution, and method for producing same by way of nucleophilic aromatic substitution, and their use in membrane processes, in particular electrochemical membrane processes such as in fuel cells, in electrolysis and in redox flow batteries.
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
C08G 73/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen, with or without oxygen or carbon, not provided for in groups
74.
MINIMALLY-INVASIVE CONTINUOUS CLINICAL MONITORING OF SMALL MOLECULES WITH ANALYTICAL ACCURACY
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (Israel)
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (Spain)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Blank, Aharon
Anders, Jens
Vidal Gancedo, José
Lloveras Monserrat, Vega
Abstract
A dendrimer including a ring core moiety, a paramagnetic group, a linking moiety and a branching moiety for continuously probing and quantifying an analyte is provided together with methods, kits and devices for performing sensitive, accurate and durable measurements.
G01N 24/10 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using electron paramagnetic resonance
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
G01R 33/60 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance using electron paramagnetic resonance
G01R 33/20 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance
G01R 33/28 - Details of apparatus provided for in groups
G01R 33/36 - Electrical details, e.g. matching or coupling of the coil to the receiver
A61L 27/50 - Materials characterised by their function or physical properties
A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
A61L 31/00 - Materials for other surgical articles
A61L 31/14 - Materials characterised by their function or physical properties
C07F 9/6581 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
C07C 33/48 - Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic part with unsaturation outside the aromatic rings
DETERMINING AN ACTUAL VALUE AND OR AN ACTUAL VALUE RANGE OF AT LEAST ONE STATE VARIABLE OF A FLUID IN A FLUID FLOW BY MEANS OF AT LEAST ONE INDICATOR PARTICLE
The invention relates to a method for determining an actual value and/or an actual value range of at least one state variable of a fluid in a fluid flow by means of at least one indicator particle (9) introduced into the fluid. In addition, it is proposed that the at least one indicator particle (9) is designed and provided for an irreversible property change of an indicator property of the indicator particle (9) in the case of a certain indicator value of the at least one state variable in the fluid flow and/or as a clear function of the actual value when a certain time period has elapsed after the indicator particle (9) has been introduced into the fluid, wherein the indicator particle (9) is detected at a detection point, the indicator property of the indicator particle (9) is evaluated and the actual value and/or the actual value range of the state variable is inferred from the indicator property downstream of the detection point. The invention also relates to a method for operating a fluid-guiding device (7), an indicator particle (9) and a device (7) for determining the actual value and/or actual value range of the at least one state variable.
G01K 11/12 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance
G01K 13/02 - Thermometers specially adapted for specific purposes for measuring temperature of moving fluids or granular materials capable of flow
G01L 11/02 - Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by means not provided for in group or by optical means
G01L 13/02 - Devices or apparatus for measuring differences of two or more fluid pressure values using elastically-deformable members or pistons as sensing elements
G01P 5/20 - Measuring speed of fluids, e.g. of air streamMeasuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring the time taken by the fluid to traverse a fixed distance using particles entrained by a fluid stream
76.
IgM and IgE heavy chain domain 2 as covalently linked homodimerization modules for the generation of fusion proteins with dual specificity
The present invention provides a polypeptides comprising a heavy chain domain 2 (HD2) from IgM or IgE and at least one pharmaceutically active moiety, complexes thereof and their use for therapy and prophylaxis.
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
The present invention relates to binding molecules comprising two polypeptide chains, wherein the peptide chains comprise modified EHD2 domains allowing heterodimerization only, thereby preventing homodimers, nucleic acids encoding such binding molecules and uses of such binding molecules or nucleic acids encoding such binding molecules in therapy.
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
The present invention relates to a trivalent binding molecule comprising a first polypeptide comprising two binding domains and a second polypeptide comprising a third binding domain. The present invention further relates to the trivalent binding molecule for use in medicine and in particular in the prophylaxis, treatment or diagnosis of a disorder or disease.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
79.
FLUORESCENCE-BASED CELLULAR ASSAY FOR THE DETECTION OF GENE-REGULATORY ACTIVITY OF CHROMATIN-ASSOCIATED PROTEINS AND PROTEIN COMPLEXES
The present invention relates to methods for the identification of co-regulatory factors that modulate the activity of (i) a chromatin-associated protein, and/or (ii) a binding partner of said chromatin-associated protein, and/or (iii) a factor that modulates the activity of said chromatin-associated protein without forming a physically stable complex with the same, in a cell.
An embodiment according to the present invention is a test arrangement for testing a DUT comprising an antenna. The test arrangement comprises a DUT-location and a probe, which comprises two conductors. The test arrangement is configured to position the probe in a proximity of the DUT-location, such that the probe is in a reactive near-field region of an antenna element of the DUT, when the DUT is placed in the DUT-location, for example, in a DUT-socket or placed in a region in which the DUT is contacted by probes.
A TEST ARRANGEMENT, AN AUTOMATED TEST EQUIPMENT AND A METHOD FOR TESTING A DEVICE UNDER TEST COMPRISING A CIRCUIT AND AN ANTENNA WHICH IS COUPLED TO THE CIRCUIT
An embodiment according to the present invention is a test arrangement for testing a DUT comprising an active circuit, and an antenna which is coupled to the circuit. The test arrangement comprises a DUT-location and a probe. Furthermore, the test arrangement comprises a ground area, which is configured to serve as an antenna ground area for an antenna of the DUT. The probe may be positioned, in a proximity of the ground area. The ground area comprises a tiny opening, such that the antenna feed impedance is not affected or not affected significantly. The DUT location is at a first side of the ground area while the probe is arranged at a second side of the ground area. The probe is adapted to weakly couple to the antenna of the DUT via the opening, in order to probe a signal when the antenna of the DUT is fed by the circuit of the DUT and/or in order to couple a signal to the antenna which is fed to the circuit of the DUT by the antenna.
A method for determining at least one physical parameter of a system comprising at least two reflection objects is presented, comprising: producing a transmission signal comprising at least one modulated electromagnetic or acoustic wave; receiving a first reception signal that is based on the transmission signal reflected by a first reflection object; receiving a second reception signal that is based on the transmission signal reflected by a second reflection object; receiving a third or further reception signal(s) that is/are based on the transmission signal reflected by a first or second or further reflection object(s); ascertaining the at least one physical parameter of the system on the basis of the first reception signal and further reception signals; ascertaining unknown distances between reflection objects or material properties, composition or nature of the media between the reflection objects of the system on the basis of the first reception signal and further reception signals.
G01S 13/34 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated using transmission of continuous, frequency-modulated waves while heterodyning the received signal, or a signal derived therefrom, with a locally-generated signal related to the contemporaneously transmitted signal
G01N 22/00 - Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
G01N 29/12 - Analysing solids by measuring frequency or resonance of acoustic waves
G01S 15/34 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated using transmission of continuous, frequency-modulated waves while heterodyning the received signal, or a signal derived therefrom, with a locally-generated signal related to the contemporaneously transmitted signal
The present invention relates to a modular multivalent antigen-binding protein complex, use of the antigen-binding protein complex in medicine and use of the antigen-binding protein complex in the prophylaxis, treatment or diagnosis of a disorder or disease.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
The present invention relates to an arrangement and a method for single-shot interferometry which can be used for detecting distance, profile, shape, undulation, roughness or the optical path length in or on optically rough or smooth objects or else for optical coherence tomography (OCT). The arrangement comprises a light source, an interferometer, in which an end reflector is arranged in the reference beam path, and also a detector for detecting an interferogram. In the reference beam path of the interferometer, the end reflector can be embodied with three plane reflecting surfaces as a prism mirror or air mirror assembly in order to generate between reference and object beams a lateral shear of magnitude delta_q for obtaining a spatial interferogram. The embodiment of said assembly with regard to the angles and the arrangement of the reflecting surfaces makes possible a large aperture angle for a high numerical aperture. In the method, in the reference beam path it is possible to carry out a reduction of the aperture angle of the reference beam using beam-limiting means in order to achieve an optimum adaptation to the geometrically given aperture angle of the end reflector in the reference beam path, which is designed to be smaller than the aperture angle in the object beam path. The end reflector in the reference beam path can also be used as part of a second interferometer for high-resolution measurement of the displacement of the arrangement for single-shot interferometry, wherein said displacement serves for focusing. The end reflector is embodied as a triple reflection arrangement (e.g. a prism arrangement) having three reflecting surfaces. The triple reflection arrangement can have an M- or W-beam path, a non-intersecting zigzag beam path or an intersecting (zigzag) beam path.
The present invention relates to polypeptide consisting of three TNF homology domains of TNF-ligand family members proteins (THD) that specifically bind to the extracellular part of TNFR2, wherein C-terminal and N-terminal reference points are defined by consensus sequences. The THDs are linked by short stretches of further C-terminal and/or N-terminal amino acids of the THD or variants thereof as well as by peptide linkers. These peptides have an improved stability. Furthermore the invention relates to polypeptide multimers comprising several of the polypeptides of the present invention.
The present invention relates to a method and an assembly for chromatic confocal spectral interferometery, in particular also for spectral domain OCT (SD-OCT) using multi-spectral light. A multiple (e.g. two, three, four, etc.) axial splitting of foci in the interferometric object arm is performed using a multifocal (e.g. bifocal, trifocal, quattro-focal, etc.) optical component, forming thereby at least two, three or even several groups of chromatically split foci in the depth direction. The multifocal optical component is made of a diffractive optical element (712) and a Schwarzschild objective (5). At least two, three, four or even more differently colored foci of different groups of foci coincide in at least one confocal point in the object space of the setup. Thus, at least two, three or even more spectral wavelets are formed in the case of optical scanning of an object measurement point and spectral detection in the wavenumber domain, which wavelets are at least slightly spectrally separated from each other. This results in a significant increase in the optical primary data in the wavenumber domain and reduces the trade-off of the chromatic confocal spectral interferometry between axial measurement range and depth resolution. From the detected data, it is possible to calculate tan (alpha) as the quotient of the absolute phase shift delta_phi and the associated wavenumber difference delta_k, the Fourier transform over the spectral data, in order to respectively determine the optical path difference.
METHOD FOR DEFINING A MOTION PATH OF AN ADDITIVE OR SUBTRACTIVE TOOL, METHOD FOR THE MATERIAL-REMOVING MACHINING OF A WORKPIECE BY MEANS OF A LASER BEAM, AND SYSTEM THEREFOR
The invention relates to the field of workpiece machining and workpiece construction. The invention relates in particular to a method for defining a motion path (90, 190, 290) of an additive or subtractive tool or a laser beam used as a tool. For this purpose, the method defines a motion path (90, 190, 290) that comprises, in at least one subregion (80, 180, 280) on the machining plane (22), a hatching of straight path segments that are parallel to one another, which path segments are angled by a hatching direction (A, B, C) relative to a reference direction (33). The method according to the invention is used to define said hatching angles (A, B, C) using a Radon transform.
G05B 19/4093 - Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by part programming, e.g. entry of geometrical information as taken from a technical drawing, combining this with machining and material information to obtain control information, named part programme, for the NC machine
88.
METHOD FOR OBTAINING FUCOXANTHIN AND FATTY ACIDS FROM THE BIOMASS OF ALGAE
FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Germany)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Derwenskus, Felix
Schmid-Staiger, Ulrike
Bringmann, Christian
Abstract
The invention relates to methods for obtaining a fucoxanthin-crystal-containing precipitate, in particular fucoxanthin crystals, in particular fucoxanthin, and a fatty acid-containing lipid fraction, in particular fatty acids, from the biomass of algae, in particular methods for the integrated extraction and separation of fucoxanthin and fatty acids from the biomass of algae, and to the products obtained from these methods, in particular fucoxanthin crystals and fatty acids.
A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
A61K 36/03 - Phaeophycota or phaeophyta (brown algae), e.g. Fucus
The invention relates to a method for routing in a network. The network consists of a plurality of network nodes. The network may have different interlinks and connections from one network node to the others. An actual topology for the network is thus created. According to the invention, the routing is performed in two phases. Firstly, the number of possible links to the network nodes is reduced in a reduction phase. A reduced topology is thus created, in which network nodes or links to network nodes which are not required for route finding are discarded. In a subsequent routing and time planning phase, an optimised route to a network node in the reduced topology is then calculated.
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (Germany)
Inventor
Steinle, Tobias
Gerhardt, Ilja
Greiner, Johannes Nikolaus
Giessen, Harald
Abstract
An apparatus and a corresponding method for generating at least one random number are disclosed. The apparatus includes an optical parametric oscillator being pumped by a pump signal with a predetermined pump power and a predetermined pump frequency. The optical parametric oscillator is configured to operate in a period multiplication state for providing an oscillator output signal of alternating light pulses, the oscillator output signal having a period that is N-times the period of the pump signal, where N is an integer and N>I. The apparatus also includes a comparing unit being configured to compare the output signal with a reference signal, wherein the reference signal has a frequency that is 1/N of the predetermined pump frequency, and an evaluation unit being configured to generate the at least one random number based on the comparison of the output signal with the reference signal.
G06F 7/58 - Random or pseudo-random number generators
G02F 1/39 - Non-linear optics for parametric generation or amplification of light, infrared, or ultraviolet waves
H01S 3/108 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity using non-linear optical devices, e.g. exhibiting Brillouin or Raman scattering
91.
CATALYST SYSTEM FOR THE PREPARATION OF HIGH-MOLECULAR WEIGHT POLYETHER AND APPLICATION THEREOF
Compositions and catalyst systems for the synthesis of polyethers from epoxide monomers are described, wherein the catalyst systems comprise an N-heterocyclic olefin and a Lewis acid (L). The catalyst systems are useful in a process for the production of polyethers by reacting an epoxide compound in the presence of the N- heterocyclic olefin/Lewis acid catalyst and has been shown to provide very high molecular weigth polyethers with an Mn which may range to more than 800.000 g/mol. The presented process is further characterized by well-available catalyst components and high polymerization rates.
C08G 65/26 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
92.
METHOD AND APPARATUS FOR DETECTING ELECTRICALLY CONDUCTIVE FOREIGN BODIES DURING INDUCTIVE ENERGY TRANSMISSION
In a method and an apparatus for detecting electrically conductive foreign bodies during inductive energy transmission between a primary coil (1) and a secondary coil (2), at least one sensor coil (5) is arranged between the primary coil (1) and the secondary coil (2), and a current flowing in the sensor coil (5) due to the induced voltage during the energy transmission is detected and evaluated. In this case, the sensor coil (5) is connected to at least one capacitor to form a resonant circuit which is matched to the excitation frequency of the primary coil (1). The phase position of the current in the resonant circuit in relation to a reference signal is then used to determine whether there are electrically conductive foreign bodies (4) between the primary coil (1) and the secondary coil (2). A high degree of sensitivity in relation to small electrically conductive foreign bodies within the energy transmission path is also achieved by means of the method and the apparatus.
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
H02J 50/60 - Circuit arrangements or systems for wireless supply or distribution of electric power responsive to the presence of foreign objects, e.g. detection of living beings
The present invention provides a protein complex comprising heterodimerizing regions HRI and HRII, each comprised of antiparallel β-strands and intervening regions wherein HRI and HRII are each interspersed fusion proteins of two human constant regions of an immunoglobulin or immunoglobulin-like proteins. The present invention also provides nucleic acid molecules comprising a sequence encoding said protein complexes and vectors comprising the nucleic acid. The present invention also provides the protein complex, the nucleic acid and the vector for use as a medicament. The present invention further provides a method of determining the amino acid sequence of HRI and/or of the amino acid sequence of HRII. The present invention also provides a method of producing amino acid chains of HRI and/or amino acid chains of HRII. The present invention further provides the protein complex for use in the N prophylaxis, treatment or diagnosis of a disorder or a disease.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
C07K 16/30 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
C07K 16/40 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against enzymes
Proposed are an arrangement and a method for depth-scanning strip triangulation with internal or external depth scan, particularly also for the 3D shape measurement in microscopy and mesoscopy. The robustness of the measurement with wavelet signal generation from an image stack is to be increased. The occurrence of the known and very undesirable 2Pi phase jumps in the phase map is to be avoided as much as possible. To do this, with a measurement instead of a wavelet at least two wavelets with contrast envelope are generated. This is done by a concurrent—then preferably with spectral separation—or by a sequential projection of two strip images with different triangulation wavelengths on the measured object.
G01B 11/25 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures by projecting a pattern, e.g. moiré fringes, on the object
G01C 11/30 - Interpretation of pictures by triangulation
95.
METHOD FOR PRODUCING AT LEAST ONE TOOTHING ON A COMPONENT AND TOOL FOR CARRYING OUT THE METHOD
The invention relates to a method (164) for producing at least one toothing on a component, to a computer program, which is configured in order to carry out the steps of the method, and to a tool (110) for carrying out the method. The method (164) comprises the following steps: a) providing a tool (110) which has a cutout (120) for guiding the component along a predetermined path (122), the cutout (120) comprising at least one preforming zone (126) and a stamping zone (128) at least along the path (122), at least the preforming zone (126) having at least one undercut (140) introduced into the cutout (120), and the stamping zone (128) having a contour (144) for producing a toothing on the component; b) introducing the component into the tool (110) and applying force to the component for guiding the component along the path (122) in such a way that in this case the component first of all passes through the preforming zone (126) and subsequently the stamping zone (128), wherein the component in the preforming zone (126) is first of all brought into a preform (152) and in the stamping zone (128) the component is then provided with a final contour (144), the final contour (144) comprising the toothing to be produced; and c) removing the component which has the final contour (144). According to the invention, friction-induced losses between the tool (110) and the component to be formed can be considerably reduced. As a result, both the material of the tool (110) and the material of the component to be formed can be relieved of strain. Thus, in this way the advantages of the successive shaping over a long reshaping zone can be utilized.
122) of the primary coil arrangement. The primary circuits are tuned to the same resonant frequency and each comprise one of the individual coils (A, B, C) or a series connection of a plurality of the individual coils (A, B, C). The proposed device makes it possible to supply different types of vehicles having different ground clearances with energy inductively in a non-contact manner, wherein charging power and also current and voltage levels remain the same here at the operating point.
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
B60L 53/30 - Constructional details of charging stations
B60L 53/39 - Means for automatic or assisted adjustment of the relative position of charging devices and vehicles specially adapted for charging by inductive energy transfer with position-responsive activation of primary coils
97.
Method and program product for operating a drive train
A method for operating a drive train having a power generator, a mechanical power transmission device, and a power receiver wherein the power transmission device is monitored to detect mechanical damage and/or the development of mechanical damage to the power transmission device, wherein detected damage and/or detected damage development is localized and the power generator, the power transmission device, and/or the power receiver are/is controlled such that a mechanical load at the localized damage location and/or damage development location is selectively reduced. A program product including program code sections with which such a method is feasible when the program product is executed on a programmable controller, a computer, or other programmable device.
MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (Germany)
UNIVERSITÄT STUTTGART (Germany)
Inventor
Hackner, Maximilian
Jahnke, Timotheus
Burghard, Zaklina
Micoulet, Alexandre
Spatz, Joachim P.
Möller, Martin
Abstract
The present invention relates to a network of metal fibers, comprising a plurality of metal fibers fixed to one another; wherein at least some of the plurality of metal fibers have a length of 1.0 mm or more, a width of 100 pm or less and a thickness of 50 pm or less. The invention further relates to a method comprising step 1 of producing a plurality of metal fibers (2) by melt spinning; step 2 of providing a loose network of metal fibers (2) produced in step 1; and step 3 of fixating the plurality of metal fibers to one another by one of the following processes d to c4.
The invention relates to a floating support structure (10) for a wind turbine (100) which is designed with a view to reducing outlay on manufacturing and materials for floating support structures for wind turbines, and is developed with a central main buoyancy body (12) and a plurality of secondary buoyancy bodies (14) arranged at the corners of a polygon around the main buoyancy body (12), wherein the secondary buoyancy bodies (14) are each connected to the main buoyancy body (12) by means of a strut (18) extending, particularly in a straight line, from the secondary buoyancy bodies (14) to the main buoyancy body (12), and wherein the secondary buoyancy bodies (14) are coupled to one another by means of a tension means (20), which connects adjacent secondary buoyancy bodies (14) to each other, in such a manner that the secondary buoyancy bodies (14) are tensioned against the main buoyancy body (12). The invention also relates to a wind turbine (100) having a floating support structure (10) of this kind.
An endoscope includes a shaft having a distal end, an optical imaging device at the distal end of the shaft for producing a real image of an object observed by means of the endoscope and at least one of an image transfer device for transmitting the real image and an image sensor for capturing the real image. The imaging device has curved light-refracting interfaces, which are tilted in relation to one another.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
G02B 23/24 - Instruments for viewing the inside of hollow bodies, e.g. fibrescopes
A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances