Abstract

A solar cell comprising a substrate, an active layer comprising a perovskite material or a polymer material, the active layer being configured to absorb at least a portion of light incident on the solar cell and to convert the absorbed portion of light into a plurality of charge carriers, a first electrode configured to be opaque and/or to reflect light transmitted through the active layer towards the active layer, and a second electrode configured to be transparent to the portion of light to be absorbed by the active layer, wherein the active layer is arranged between the first and second electrodes and the first electrode is arranged between the substrate and the active layer, and wherein the solar cell is configured such that a work function of the first electrode is different from a work function of the second electrode.

IPC Classes  ?

• H10K 30/15 - Sensitised wide-bandgap semiconductor devices, e.g. dye-sensitised TiO2
• H10K 30/50 - Photovoltaic [PV] devices
• H10K 30/82 - Transparent electrodes, e.g. indium tin oxide [ITO] electrodes
• H10K 77/10 - Substrates, e.g. flexible substrates
• H10K 85/50 - Organic perovskitesHybrid organic-inorganic perovskites [HOIP], e.g. CH3NH3PbI3

Abstract

A process for preparing a polyurea by dehydrogenative coupling of an amine compound amine compound containing at least two non-tertiary amino groups and methanol, comprising reacting the amine compound and methanol in the presence of a metal pincer catalyst and a base to form a polyurea and hydrogen gas.

IPC Classes  ?

• C08G 71/02 - Polyureas

Abstract

A composition having the general formula: NaaMnbFecTidMeO2, wherein: M comprises one or more elements selected from the group consisting of aluminium, magnesium, zinc, copper, silicon, and zirconium; and wherein: 0.5

IPC Classes  ?

• C01G 49/00 - Compounds of iron
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

An apparatus (50) for detecting a first analyte (42) comprises a first layer (51) comprising a photoluminescent material; and a second layer (52) provided on the first layer (51), wherein the second layer (52) comprises a polymeric material configured to allow the first analyte (42) to permeate through the second layer (52).

IPC Classes  ?

• G01N 21/64 - FluorescencePhosphorescence

Abstract

A heterocyclic compound represented by Formula 1, an organic light-emitting device including the same, and an electronic apparatus including the organic light-emitting device: A heterocyclic compound represented by Formula 1, an organic light-emitting device including the same, and an electronic apparatus including the organic light-emitting device: wherein Formula 1 is the same as described in the detailed description.

IPC Classes  ?

• H10K 50/12 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising dopants
• C07F 5/02 - Boron compounds
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• H10K 85/60 - Organic compounds having low molecular weight

Abstract

M&C PG450501WO 42 55209372-1 ABSTRACT ELECTRICALLY-PUMPED ORGANIC SEMICONDUCTOR LASER ARRANGEMENT An electrically-pumped organic semiconductor laser arrangement comprises an 5 OLED pump arrangement and an optically-pumped organic semiconductor laser. The OLED pump arrangement is configured to emit pump light from one or more emission regions of the OLED pump arrangement. The optically-pumped organic semiconductor laser includes a laser active layer and a grating structure for feedback of laser light in a grating region of the laser active layer along a feedback direction which is parallel to 10 the laser active layer. The one or more emission regions of the OLED pump arrangement are aligned with the grating region of the laser active layer for illumination of a region of the laser active layer with the pump light, which illuminated region comprises at least a portion of the grating region of the laser active layer, wherein the optically-pumped organic semiconductor laser is configured to emit laser light from at 15 least a portion of the illuminated region, and wherein the illuminated region of the laser active layer is elongated in a direction parallel to the laser active layer. [FIG. 1A]

IPC Classes  ?

• H01S 5/026 - Monolithically integrated components, e.g. waveguides, monitoring photo-detectors or drivers
• H01S 5/04 - Processes or apparatus for excitation, e.g. pumping
• H01S 5/187 - Surface-emitting [SE] lasers, e.g. having both horizontal and vertical cavities having only horizontal cavities, e.g. horizontal cavity surface-emitting lasers [HCSEL] using Bragg reflection
• H01S 5/36 - Structure or shape of the active regionMaterials used for the active region comprising organic materials
• H10K 59/00 - Integrated devices, or assemblies of multiple devices, comprising at least one organic light-emitting element covered by group
• H10K 59/80 - Constructional details
• H10K 77/10 - Substrates, e.g. flexible substrates
• H01S 5/12 - Construction or shape of the optical resonator the resonator having a periodic structure, e.g. in distributed feedback [DFB] lasers
• H01S 5/02 - Structural details or components not essential to laser action
• H01S 5/00 - Semiconductor lasers
• H10K 102/00 - Constructional details relating to the organic devices covered by this subclass

Abstract

Detection system which comprise a CRISPR-associated effector protein programmed with a molecule binding (by complementary base pairing) a target nucleic acid. On binding of an RNA, Cas10 can generate cyclic oligoadenylate (COA) which in turn activates a nuclease, e.g. NucC. The nuclease can, via a reporter system, generate a readily detectable fluorescent/coloured signal. Preferred embodiments employ the Cas10 and NucC from Vibrio metoccus.

IPC Classes  ?

• C12N 9/22 - Ribonucleases
• C12Q 1/682 - Signal amplification
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage

Abstract

The present invention relates to the field of catalytic hydrogenation and, more particularly, to methods of manganese-catalysed asymmetric hydrogenation of prochiral ketimine moieties to chiral amines.

IPC Classes  ?

• C07C 209/02 - Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of hydrogen atoms by amino groups
• B01J 31/18 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony
• C07C 211/42 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
• C07C 211/45 - Monoamines
• C07C 217/84 - Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
• C07C 209/52 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
• C07C 213/02 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
• C07F 9/36 - Amides thereof

Abstract

Disclosed is an aminopeptidase (having a protease associated (PA) domain and a (catalytic) protease domain (PD)) that is self-regulated whereby the C-terminal portion of the aminopeptidase sequence binds in a cleft between the PA domain and the PD thereby inhibiting enzyme activity. Additionally, it has also been shown that disrupting the interaction between the C-terminal portion of the aminopeptidase sequence and its binding location between the PA and PD, represents a mechanism by which the aminopeptidase may be switched from being inhibited (and inactive) to uninhibited and active. An aminopeptidase of the present disclosure may comprise a protease associated (PA) domain; and a (catalytic) protease domain (PD)).

IPC Classes  ?

• C12N 9/48 - Hydrolases (3.) acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
• A61K 38/08 - Peptides having 5 to 11 amino acids
• C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
• C07K 14/21 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pseudomonadaceae (F)
• C12N 9/52 - Proteinases derived from bacteria

Abstract

The present invention relates to mixed phase layered sodium metal oxide materials, which have been found to have properties that are advantageous for use of the materials in sodium-ion batteries. The present invention also relates to a method of forming such materials via a sol-gel route. Electrodes comprising the layered sodium metal oxide materials as well as energy storage devices comprising the layered sodium metal oxide materials are also considered.

IPC Classes  ?

• H01M 4/04 - Processes of manufacture in general
• H01M 4/1391 - Processes of manufacture of electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• C01G 53/00 - Compounds of nickel

Abstract

A TADF dendrimer of formula (I), (Ar1)m—(Ar2)—(X)n, wherein: Ar2 is a pyridine, pyrimidine, pyrazine, pyridazine, triazine or tetrazine ring group; m is from 1 to 5; n is 0, 1 or 2; each Ar1 is a six-membered aromatic or heteroaromatic ring comprising at least one dendron Z positioned meta to the ring position on Ar1 where Ar1 is attached to acceptor core Ar2. Dendrons Z are carbazole-based.

IPC Classes  ?

• H10K 85/60 - Organic compounds having low molecular weight
• C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

An article (5) comprises a textile substrate (10); and a composition (20) comprising a MOF which has been functionalised with an organic functionalising compound capable of interacting with and/or capable of blocking one or more pathogens, wherein at least a portion of the textile substrate (10) comprises, is treated with or coated with the composition.

IPC Classes  ?

• A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

Abstract

The present disclosure provides a cohort of novel viral genome derived products for use, for example, in medicine, as a medicaments, as expression vectors and as adjuvants. The disclosed viral genome derived products may be derived from members of the Paramyxoviridae Family which contains a wide variety of vertebrate viruses, including mumps, measles and human parainfluenza viruses.

IPC Classes  ?

• C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
• C12N 15/86 - Viral vectors

Abstract

A family of structurally related proteins has been found to have enzymatic activity. The protein family may comprise DUF1874 proteins. Members of this family can be used to modulate the structure, function and/or activity of a cellular signalling molecule that is associated with a cellular antiviral response. In particular, the proteins described herein exhibit an ability to modulate the function, structure and/or activity of cyclic oligoadenylate (cOA); that is to say they can be used to inhibit, destroy, ablate and/or breakdown cOA activity, structure and/or function. The disclosed proteins (all of which belong to the DUF1874 protein family) are generally referred to as “ring nucleases”.

IPC Classes  ?

• C12N 9/22 - Ribonucleases
• A61P 31/04 - Antibacterial agents
• G01N 33/573 - ImmunoassayBiospecific binding assayMaterials therefor for enzymes or isoenzymes

Abstract

Naaa Mnbb Fecc Tidd Mee O22 Mabc dee ≤ 0.5, and wherein the composition is a layered sodium metal oxide material having at least a first phase and a second phase, wherein each phase is different and independently comprises one or more P2-type structures, one or more O3-type structures or one or more P3-type structures. Also described are methods of synthesizing layered sodium metal oxide materials as well as electrodes and energy storage devices including such compositions.

IPC Classes  ?

• C01G 49/00 - Compounds of iron
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

An apparatus (50) for detecting a first analyte (42) comprises a first layer (51) comprising a photoluminescent material; and a second layer (52) provided on the first layer (51), wherein the second layer (52) comprises a polymeric material configured to allow the first analyte (42) to permeate through the second layer (52).

IPC Classes  ?

• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
• G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators

Abstract

An apparatus (50) for detecting a first analyte (42) comprises a first layer (51) comprising a photoluminescent material; and a second layer (52) provided on the first layer (51), wherein the second layer (52) comprises a polymeric material configured to allow the first analyte (42) to permeate through the second layer (52).

IPC Classes  ?

• G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour

Abstract

The present invention concerns Amyloid Binding Alcohol Dehydrogenase (ABAD) inhibitors (I) or (II) that interact non- competitively with nicotinamide adenine dinucleotide + H (NADH). Inhibition of ABAD is useful in the treatment or prophylaxis of disease, including Alzheimer's disease (AD) and cancer. Accordingly, the present invention also concerns ABAD inhibitors for use as a medicament, specifically for use in the treatment of Alzheimer's disease and/or cancer.

IPC Classes  ?

• C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 403/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 409/06 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 413/06 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• A61K 31/401 - ProlineDerivatives thereof, e.g. captopril
• A61K 31/404 - Indoles, e.g. pindolol
• A61K 31/41 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
• A61K 31/498 - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 35/00 - Antineoplastic agents

Abstract

The invention relates to spiro-(fluorene-9,9'-(thio)xanthene)-based compounds (I) and a process for the preparation of these. The compounds are useful as thermally activated delayed fluorescence material in electroluminescent devices such as organic light-emitting diodes (OLEDs). The invention extends to electroluminescent devices comprising one or more of these compounds as an emitter and a host material.

IPC Classes  ?

• C07F 9/6547 - Six-membered rings condensed with carbocyclic rings or ring systems
• C07F 9/655 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof

Abstract

Detection system which comprise a CRISPR-associated effector protein programmed with a molecule binding (by complementary base pairing) a target nucleic acid. On binding of an RNA, Cas10 can generate cyclic oligoadenylate (cOA) which in turn activates a nuclease, e.g. NucC. The nuclease can, via a reporter system, generate a readily detectable fluorescent/coloured signal. Preferred embodiments employ the Cas10 and NucC from Vibrio metoecus.

IPC Classes  ?

• C12Q 1/682 - Signal amplification
• C12Q 1/6816 - Hybridisation assays characterised by the detection means
• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes

Abstract

A process for preparing a polyurea by dehydrogenative coupling of an amine compound amine compound containing at least two non-tertiary amino groups and methanol, comprising reacting the amine compound and methanol in the presence of a metal pincer catalyst and a base to form a polyurea and hydrogen gas.

IPC Classes  ?

• C08G 71/02 - Polyureas

Abstract

1m2n2122. Dendrons Z are carbazole-based.

IPC Classes  ?

• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
• C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof

Abstract

The invention provides a method comprising hydrogenating a ketone in the presence of (i) a base, (ii) hydrogen gas and (iii) a catalyst comprising a charged or neutral complex of formula (I): The invention provides a method comprising hydrogenating a ketone in the presence of (i) a base, (ii) hydrogen gas and (iii) a catalyst comprising a charged or neutral complex of formula (I): wherein: Mn is a manganese atom or a manganese ion in oxidation state (I) to (VII); R1 and R2 are each independently optionally substituted C4-8monocyclic aryl or C3-7monocyclic heteroaryl moieties; -Fc- denotes a ferrocene (bis(η5-cyclopentadienyl)iron) moiety covalently bonded via adjacent carbon atoms of one of the two cyclopentadienyl moieties, and which may be optionally further substituted, in either cyclopentadienyl ring; —Z— is an alkylene linker of the formula —(CH2)1-6— in which one or more of the hydrogen atoms of the alkylene may be independently substituted; —Nx is an optionally substituted nitrogen-containing heteroaryl moiety, with the proviso that at least one of R1, R2 and —Nx is substituted one or more times with an electron donating group; and L1-L3 constitute one, two or three ligands, wherein, when the complex of formula (I) is charged, the catalyst comprises one or more additional counterions to balance the charge of the complex.

IPC Classes  ?

• C07C 29/156 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used containing iron group metals, platinum group metals, or compounds thereof
• B01J 31/18 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony
• C07F 17/02 - Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Abstract

3.

IPC Classes  ?

• B01J 23/04 - Alkali metals
• B01J 6/00 - CalciningFusing
• B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
• B01J 35/40 - Catalysts, in general, characterised by their form or physical properties characterised by dimensions, e.g. grain size
• B01J 35/56 - Foraminous structures having flow-through passages or channels, e.g. grids or three-dimensional monoliths
• B01J 37/00 - Processes, in general, for preparing catalystsProcesses, in general, for activation of catalysts
• C11C 3/10 - Ester interchange

Abstract

The present disclosure is based on the identification of a novel sequence motif present in halogenase type enzymes. From this, the disclosure provides methods for identifying and or detecting halogenases (halogenating enzymes) and novel halogenases identifiable using such methods. The disclosure also provides a novel cohort of enzymes and novel methods for achieving substrate halogenation.

IPC Classes  ?

• G16B 30/10 - Sequence alignmentHomology search
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• G16B 30/20 - Sequence assembly
• C12P 1/00 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes

Abstract

A security or identification device comprises a membrane laser structure configured to be optically pumped. The membrane laser structure comprises a flexible emission layer comprising a gain material; and one or more structures formed in or associated with the flexible emission layer and configured to provide optical feedback in the emission layer to produce a laser light output having at least one property representing an identifier.

IPC Classes  ?

• G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation
• H01S 5/36 - Structure or shape of the active regionMaterials used for the active region comprising organic materials
• B42D 25/328 - Diffraction gratingsHolograms
• B42D 25/36 - Identification or security features, e.g. for preventing forgery comprising special materials
• B42D 25/45 - Associating two or more layers
• G06K 7/12 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using a selected wavelength, e.g. to sense red marks and ignore blue marks
• G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
• H01S 5/04 - Processes or apparatus for excitation, e.g. pumping
• H01S 5/183 - Surface-emitting [SE] lasers, e.g. having both horizontal and vertical cavities having only vertical cavities, e.g. vertical cavity surface-emitting lasers [VCSEL]
• B42D 25/21 - Information-bearing cards or sheet-like structures characterised by identification or security featuresManufacture thereof characterised by a particular use or purpose for multiple purposes
• B42D 25/29 - Securities Bank notes
• G07D 7/1205 - Testing spectral properties
• G07D 7/202 - Testing patterns thereon using pattern matching

Abstract

An apparatus for analysing a liquid sample comprising particles, comprises: a first chamber (12) and a second chamber (14), and an optical path between the first chamber (12) and the second chamber (14), wherein: the first chamber (12) is a sample chamber comprising: a sample space for receiving the sample; a light input (24) for input of light into the first chamber (12) for interaction with the sample; and an exit aperture (26) arranged for scattered and/or reflected light to pass from the first chamber via the optical path to the second chamber (14); the second chamber (14) is a detection chamber comprising: an input aperture (28) for receiving light from the optical path; and a detector (25) for detecting, or a detector aperture for receiving, light to be detected; wherein the first chamber (12) and the second chamber (14) provide at least one light integrating volume, and wherein the first chamber (12) is configured such that in operation the liquid sample is present in the first chamber (12) and isolated from the second chamber (14).

IPC Classes  ?

• G01N 21/03 - Cuvette constructions
• G01N 21/51 - Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule

Abstract

The present invention relates to the field of catalytic hydrogenation and, more particularly, to methods of manganese-catalysed hydrogenation of esters to alcohols. Advantageously, where the esters are chiral, the hydrogenations proceed with high or complete stereochemical integrity.

IPC Classes  ?

• C07D 307/77 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
• B01J 31/18 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony
• B01J 31/22 - Organic complexes

Abstract

A light sheet imaging system, such as a light sheet microscope, comprises an illumination arrangement for generating a light sheet for three-photon excitation of a fluorescent sample, and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam. A method of light sheet imaging comprises using a light sheet for three-photon excitation of a fluorescent sample, and collecting fluorescence generated in the sample as a result of three-photon excitation of the sample by the light sheet. Such a method may be used for light sheet microscopy.

IPC Classes  ?

• G02B 21/00 - Microscopes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

A holographic security or identification device (10) comprises an object, or a flexible substrate (12) configured to be conformable to a desired, curved shape; and a plurality of structures (14) formed on or in the object to have a desired curved configuration, or formed in or associated with the substrate and arranged to adopt a desired curved configuration when the substrate is conformed to a desired shape, wherein the plurality of structures (14) are configured to receive light (20) of a selected at least one wavelength or range of wavelengths and to produce, using the received light, a desired holographic image (22) for security or identification purposes when in the desired configuration.

IPC Classes  ?

• G03H 1/00 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• G03H 1/22 - Processes or apparatus for obtaining an optical image from holograms

Abstract

A method and system are disclosed for use in imaging a sample. The method comprises illuminating a sample through a scattering medium, or illuminating a sub-surface region of the sample through a scattering surface region of the sample, with a plurality of spatial patterns of incident electromagnetic radiation, wherein each spatial pattern of incident electromagnetic radiation interacts with the sample, or the sub-surface region of the sample, to generate electromagnetic radiation in the sample or the sub-surface region of the sample. The method comprises measuring, for each spatial pattern of incident electromagnetic radiation, a corresponding value representative of a quantity of at least a portion of the emitted electromagnetic radiation and using the plurality of spatial patterns of incident electromagnetic radiation and the plurality of corresponding measured values to determine an image of the sample, or an image of the sub-surface region of the sample, without using a spatial distribution of the emitted electromagnetic radiation.

IPC Classes  ?

• G01N 21/47 - Scattering, i.e. diffuse reflection
• G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
• G01N 21/64 - FluorescencePhosphorescence

Abstract

An etchant is described that includes an N-heterocyclic carbene and optionally an appropriate solvent. The etchant was effective at etching a metallic surface having, for example, a metal oxide and/or metal, in both solution phase and vapour-phase. The etchant has been shown to effectively etch oxidized copper and tungsten.

IPC Classes  ?

• C23F 1/10 - Etching compositions

Abstract

A family of structurally related proteins has been found to have enzymatic activity. The protein family may comprise DUF1874 proteins. Members of this family can be used to modulate the structure, function and/or activity of a cellular signalling molecule that is associated with a cellular antiviral response. In particular, the proteins described herein exhibit an ability to modulate the function, structure and/or activity of cyclic oligoadenylate (cOA); that is to say they can be used to inhibit, destroy, ablate and/or breakdown cOA activity, structure and/or function. The disclosed proteins (all of which belong to the DUF1874 protein family) are generally referred to as "ring nucleases".

IPC Classes  ?

• C12N 9/22 - Ribonucleases

Abstract

The invention provides a method comprising hydrogenating a ketone in the presence of (i) a base, (ii) hydrogen gas and (iii) a catalyst comprising a charged or neutral complex of formula (I): (I) wherein: Mn is a manganese atom or a manganese ion in oxidation state (I) to (VII); R1and R24-83-73-7monocyclic heteroaryl moieties; -Fc- denotes a ferrocene (bis(η|521-61-6- in which one or more of the hydrogen atoms of the alkylene may be independently substituted; -Nx is an optionally substituted nitrogen-containing heteroaryl moiety, with the proviso that at least one of R1, R2and -Nxis substituted one or more times with an electron donating group; and L1-L3 constitute one, two or three ligands, wherein, when the complex of formula (I) is charged, the catalyst comprises one or more additional counterions to balance the charge of the complex. ηη

IPC Classes  ?

• C07F 13/00 - Compounds containing elements of Groups 7 or 17 of the Periodic Table
• B01J 31/32 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups of manganese, technetium or rhenium
• C07C 29/145 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
• C07C 33/00 - Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms

Abstract

In an aspect, the present invention provides an optical encryption terminal for generating and distributing a cryptographic key signal in a cryptography key distribution system having at least two optical encryption terminals. The optical encryption terminal comprises an electronic processing unit and the optical encryption terminal is configured to selectively receive optical input signals generated by a source of electromagnetic radiation and optical input signals generated by a further optical encryption terminal, and to selectively output first optical output signals to a detection element and second optical output signals to the further optical encryption terminal, wherein the first optical output signals are based on the optical input signals generated by the further optical encryption terminal and transformed in accordance with an optical encryption pattern provided at the optical encryption terminal. Furthermore, the optical encryption terminal is configured to determine, using the electronic processing unit, a cryptographic key signal on the basis of at least one radiometric and/or photometric quantity associated with the optical output signals detected by the detection element.

IPC Classes  ?

• H04L 9/08 - Key distribution
• G01N 21/47 - Scattering, i.e. diffuse reflection
• G02B 6/42 - Coupling light guides with opto-electronic elements

Abstract

Disclosed are metal organic framework materials (MOFs), comprising an extra-framework NO releasing compound within the internal pores and/or channels of the MOF, the NO-releasing compounds and their preparation and uses. The MOFs and NO-releasing compounds are capable of releasing NO on application of an external stimulus and may provide materials with multiple modes of antibacterial and/or drug action.

IPC Classes  ?

• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61K 9/14 - Particulate form, e.g. powders
• A61K 31/155 - Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (HN=C(OH)NH2), isothiourea (HN=C(SH)—NH2)
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 47/52 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
• B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties

Abstract

326326233.

IPC Classes  ?

• B01J 23/02 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the alkali- or alkaline earth metals or beryllium
• B01J 37/08 - Heat treatment
• C11C 3/10 - Ester interchange
• C07C 67/02 - Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
• B01J 35/02 - Solids
• B01J 21/04 - Alumina
• C01B 13/18 - Methods for preparing oxides or hydroxides in general by thermal decomposition of compounds, e.g. of salts or hydroxides
• C01F 7/16 - Preparation of alkaline-earth metal aluminates or magnesium aluminatesAluminium oxide or hydroxide therefrom

Abstract

in vivoin vitroin vitro. A system for use in light-sheet imaging of an object through a scattering medium is configured to perform the method.

IPC Classes  ?

• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G02B 21/00 - Microscopes

Abstract

A method for use in imaging an object through a scattering medium comprises illuminating the object sequentially point-by-point through the scattering medium with incident electromagnetic radiation propagating along an illumination direction so that the incident electromagnetic radiation interacts with the object to cause the object to generate and emit electromagnetic radiation, wherein the incident electromagnetic radiation is formed by spectrally dispersing initial electromagnetic radiation in a direction transverse to the illumination direction so as to form spectrally dispersed electromagnetic radiation and by spatially focusing the spectrally dispersed electromagnetic radiation through the scattering medium to the object. The method comprises measuring, for each illuminated point of the object, a corresponding value representative of a quantity of at least a portion of the corresponding emitted electromagnetic radiation and using, for each illuminated point of the object, position information for the illuminated point and the corresponding measured value to determine an image of the object.

IPC Classes  ?

• G02B 21/00 - Microscopes
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

In an aspect, the present invention provides an optical encryption terminal for generating and distributing a cryptographic key signal in a cryptography key distribution system having at least two optical encryption terminals. The optical encryption terminal comprises an electronic processing unit and the optical encryption terminal is configured to selectively receive optical input signals generated by a source of electromagnetic radiation and optical input signals generated by a further optical encryption terminal, and to selectively output first optical output signals to a detection element and second optical output signals to the further optical encryption terminal, wherein the first optical output signals are based on the optical input signals generated by the further optical encryption terminal and transformed in accordance with an optical encryption pattern provided at the optical encryption terminal. Furthermore, the optical encryption terminal is configured to determine, using the electronic processing unit, a cryptographic key signal on the basis of at least one radiometric and/or photometric quantity associated with the optical output signals detected by the detection element.

IPC Classes  ?

• H04L 9/08 - Key distribution

Abstract

4 where A is Mn or Mg and x is from 0 to 0.75 under reducing conditions at a temperature of from 800 to 1500° C., and catalysts obtainable by said method.

IPC Classes  ?

• B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
• B01J 23/88 - Molybdenum
• B01J 37/08 - Heat treatment
• B01J 37/18 - Reducing with gases containing free hydrogen
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 35/10 - Solids characterised by their surface properties or porosity
• C01B 3/40 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of gaseous or liquid organic compounds with gasifying agents, e.g. water, carbon dioxide, air by reaction of hydrocarbons with gasifying agents using catalysts characterised by the catalyst
• B01J 23/889 - Manganese, technetium or rhenium

Abstract

Thermally Activated Delayed Fluorescence (TADF) compounds wherein two aromatic heterocyclic moieties are provided as acceptor groups, spaced apart from two donor moieties by an aromatic spacer ring, are described. Charged organic TADF species having a similar structure are also described. The TADF compounds and charged organic TADF species may be employed as emitter material in light emitting devices such as OLEDs and LEECs. Also described TADF compounds wherein at least one donor moiety is substituted by at least one substituent that is a phosphine oxide or a phosphine sulphide.

IPC Classes  ?

• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
• C07D 417/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• C07D 413/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
• C07F 9/572 - Five-membered rings
• C07D 265/38 - [b, e]-condensed with two six-membered rings
• C07D 279/22 - [b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
• C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
• H01L 51/50 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for light emission, e.g. organic light emitting diodes (OLED) or polymer light emitting devices (PLED)

Abstract

A classification method comprises positioning an object and a radar unit in proximity to each other; receiving by the radar unit radar signals reflected from the object; and classifying the object, wherein the classifying is based on the radar signals and/or at least one feature extracted from the radar signals, and the classifying of the object comprises determining classification data for the object.

IPC Classes  ?

• G01S 7/41 - Details of systems according to groups , , of systems according to group using analysis of echo signal for target characterisationTarget signatureTarget cross-section
• G01F 23/284 - Electromagnetic waves
• G07D 11/50 - Sorting or counting valuable papers
• G01S 7/35 - Details of non-pulse systems
• G01N 22/00 - Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more

Abstract

An optical system for generating an Airy beam light sheet comprising an optical arrangement for generating a Gaussian beam, and an optical element for converting the Gaussian beam into an Airy beam light sheet, wherein a single optical element is provided for converting the Gaussian beam into an Airy beam light sheet.

IPC Classes  ?

• G02B 26/00 - Optical devices or arrangements for the control of light using movable or deformable optical elements
• G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
• G02F 1/29 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the position or the direction of light beams, i.e. deflection
• G02B 21/06 - Means for illuminating specimen
• G02B 21/00 - Microscopes
• G02B 26/06 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the phase of light
• G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for
• G02B 26/02 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the intensity of light
• G02B 27/30 - Collimators

Abstract

An optical coherence tomography system for imaging a sample is configured so as to illuminate a region of interest of the sample with incident light from an optical source. The optical coherence tomography system is further configured so as to interfere, on an optical detector, reference light from the optical source with offset returning light emerging from the sample along an offset collection path which is spatially offset from the region of interest of the sample, thereby creating interference on the optical detector.

IPC Classes  ?

• G01B 9/02 - Interferometers

Abstract

An organic thermally activated delayed fluorescence (TADF) compound selected from the group consisting of compounds according to formula (Ia) and formula (Ib): wherein: Het is a heteroaryl group containing at least one heteroatom; n(D) denotes n donor groups D bonding to the heteroaryl group Het; n is at least 1; and -a and -b denotes bonding to another group.

IPC Classes  ?

• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07F 9/6558 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
• C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
• H01L 51/50 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for light emission, e.g. organic light emitting diodes (OLED) or polymer light emitting devices (PLED)
• H05B 33/14 - Light sources with substantially two-dimensional radiating surfaces characterised by the chemical or physical composition or the arrangement of the electroluminescent material

Abstract

An apparatus (150) comprises a first detection chamber (130) for receiving microorganisms and configured to allow detection of the microorganisms via detection of scattered light from the first detection chamber (130); a medium (120) configured to permit passage of microorganisms from a sample (110) through the medium (120) into the first detection chamber (130); and at least one second detection chamber (140) configured to allow detection of the microorganisms via detection of scattered light from the at least one second detection chamber (140).

IPC Classes  ?

• G01N 21/51 - Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
• G01N 15/06 - Investigating concentration of particle suspensions
• G01N 15/00 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials
• G01N 21/47 - Scattering, i.e. diffuse reflection
• G01N 21/11 - Filling or emptying of cuvettes

Abstract

The present disclosure is based on the identification of a novel sequence motif present in halogenase type enzymes. From this, the disclosure provides methods for identifying and or detecting halogenases (halogenating enzymes) and novel halogenases identifiable using such methods. The disclosure also provides a novel cohort of enzymes and novel methods for achieving substrate halogenation.

IPC Classes  ?

• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

Abstract

An apparatus for analysing a liquid sample comprising particles, comprises: a first chamber (12) and a second chamber (14), and an optical path between the first chamber (12) and the second chamber (14), wherein: the first chamber (12) is a sample chamber comprising: a sample space for receiving the sample; a light input (24) for input of light into the first chamber (12) for interaction with the sample; and an exit aperture (26) arranged for scattered and/or reflected light to pass from the first chamber via the optical path to the second chamber (14); the second chamber (14) is a detection chamber comprising: an input aperture (28) for receiving light from the optical path; and a detector (25) for detecting, or a detector aperture for receiving, light to be detected; wherein the first chamber (12) and the second chamber (14) provide at least one light integrating volume, and wherein the first chamber (12) is configured such that in operation the liquid sample is present in the first chamber (12) and isolated from the second chamber (14).

IPC Classes  ?

• G01N 21/03 - Cuvette constructions
• G01N 21/51 - Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule

Abstract

A Raman system for use in performing Raman spectroscopy on a sample, comprises an optical source, a spectrometer, and an optical system for coupling light from the optical source to a sample and for coupling light from the sample to the spectrometer and a further spectrometer. A Raman system for use in performing Raman spectroscopy on a sample, comprises an optical source, a spectrometer and an optical system for coupling light from the optical source and a further optical source to a sample and for coupling light from the sample to the spectrometer. The optical system may be configured for coupling light from the optical source and the further optical source to the sample and for coupling light from the sample to the spectrometer and the further spectrometer. The Raman system may be portable and/or may be configured to be transported and/or carried and/or may be handheld.

IPC Classes  ?

• G01N 21/65 - Raman scattering
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01J 3/44 - Raman spectrometryScattering spectrometry

Abstract

The present invention relates to the field of catalytic hydrogenation and, more particularly, to methods of manganese-catalysed hydrogenation of esters to alcohols. Advantageously, where the esters are chiral, the hydrogenations proceed with high or complete stereochemical integrity..

IPC Classes  ?

• C07C 213/00 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
• C07D 209/20 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
• C07C 215/24 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and acyclic
• C07C 215/28 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
• C07C 215/08 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
• C07C 29/149 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
• C07C 33/34 - Monohydroxylic alcohols containing six-membered aromatic rings and other rings

Abstract

The invention relates to a method of producing electrode materials for solid oxide cells which comprises applying an electric potential to a metal oxide which has a perovskite crystal structure. The resultant electrode catalyst exhibits excellent electrochemical performance. The invention extends to the electrode catalyst itself, and to electrodes and solid oxide cells comprising the electrode catalyst.

IPC Classes  ?

• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 8/1213 - Fuel cells with solid electrolytes operating at high temperature, e.g. with stabilised ZrO2 electrolyte characterised by the electrode/electrolyte combination or the supporting material
• H01M 4/88 - Processes of manufacture
• H01M 8/12 - Fuel cells with solid electrolytes operating at high temperature, e.g. with stabilised ZrO2 electrolyte

Abstract

A holographic security or identification device (10) comprises an object, or a flexible substrate (12) configured to be conformable to a desired, curved shape; and a plurality of structures (14) formed on or in the object to have a desired curved configuration, or formed in or associated with the substrate and arranged to adopt a desired curved configuration when the substrate is conformed to a desired shape, wherein the plurality of structures (14) are configured to receive light (20) of a selected at least one wavelength or range of wavelengths and to produce, using the received light, a desired holographic image (22) for security or identification purposes when in the desired configuration.

IPC Classes  ?

• G03H 1/00 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• G03H 1/08 - Synthesising holograms
• G03H 1/26 - Processes or apparatus specially adapted to produce multiple holograms or to obtain images from them, e.g. multicolour technique

Goods & Services

Optical apparatus and instruments; optical apparatus and instruments for scientific or laboratory purposes; microscopes; super-resolution microscopes; optical microscopes for use in revealing sub-cellular processes; biological microscopes; microscopes with single-PIXel detection capability; microscopes for obtaining wide-field images within or through biological tissue; cell observing devices; microscopic apparatus and instruments for use in research relating to cells, tissue and inert particles; microscopic apparatus and instruments for use in research relating to the biological sciences, drug discovery and early diagnosis of disease; optical microscopes for use in ophthalmology, neuroscience and developmental biology; optical microscopes for use in the analysis of cells, tissue, inert particles and turbid media; optical microscopes for use in the biological sciences, drug discovery and early diagnosis of disease; optical microscopes for use in the diagnosis of nephrotic disease; optical microscopes for use in the diagnosis of platelet granule disorders; parts and fittings for all the aforesaid goods. Medical apparatus and instruments; diagnostic apparatus for medical purposes; optical devices for medical purposes; optical imaging devices for medical purposes; parts and fittings for all the aforesaid goods. Medical services; medical care; provision of medical information incorporating imaging data via microscopy; provision of medical information via microscopy; provision of medical information relating to the use of microscopes in the field of ophthalmology, neuroscience and developmental biology; provision of medical information relating to the use of optical microscopes in the medical analysis of cells, tissue, inert particles and turbid media; provision of medical information relating to the use of optical microscopes in the biological sciences, drug discovery and early diagnosis of disease.

Abstract

A method and system are disclosed for use in imaging a sample. The method comprises illuminating a sample through a scattering medium, or illuminating a sub-surface region of the sample through a scattering surface region of the sample, with a plurality of spatial patterns of incident electromagnetic radiation, wherein each spatial pattern of incident electromagnetic radiation interacts with the sample, or the sub-surface region of the sample, to generate electromagnetic radiation in the sample or the sub-surface region of the sample. The method comprises measuring, for each spatial pattern of incident electromagnetic radiation, a corresponding value representative of a quantity of at least a portion of the emitted electromagnetic radiation and using the plurality of spatial patterns of incident electromagnetic radiation and the plurality of corresponding measured values to determine an image of the sample, or an image of the sub-surface region of the sample, without using a spatial distribution of the emitted electromagnetic radiation.

IPC Classes  ?

• G02B 21/00 - Microscopes
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

This invention relates to the biosynthetic production of macrocyclic molecules from linear precursor peptides that contain highly truncated C terminal recognition sequences of 10 or fewer residues using prolyl oligopeptidase (POP) macrocyclases. This may be useful for example in the biosynthetic production of macrocyclic molecules. Methods and kits for the production of macrocyclic molecules, as well as libraries and methods of screening, are provided.

IPC Classes  ?

• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids

Abstract

A catalyst obtainable by exsolving particles of Ni, Co and/or a mixture of Ni and Co from a perovskite metal oxide of formula (I) (M1aaM2bxyyM3z33, wherein M1and M2are each independently an alkali earth metal or a rare earth metal, M3 is Ti or Cr, 0 ≤ a ≤ 1, 0 ≤ b ≤ 1, 0 < a + b ≤1, 0 ≤ x < 1, 0 ≤ y < 1, 0 ≤ z < 1, x + y + z = 1 and where at least one of x and y > 0. The invention includes methods of converting this catalyst into one or more catalytically active forms. The catalysts and the activated forms of same are useful in the catalysing CO oxidation and/or NO oxidation.

IPC Classes  ?

• B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
• B01J 23/83 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with rare earths or actinides
• B01J 23/86 - Chromium
• B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 35/02 - Solids
• B01J 37/18 - Reducing with gases containing free hydrogen
• B01J 38/10 - Gas or vapour treatingTreating by using liquids vaporisable upon contacting spent catalyst using elemental hydrogen
• B01J 38/14 - Treating with free oxygen-containing gas with control of oxygen content in oxidation gas
• B01J 38/18 - Treating with free oxygen-containing gas with subsequent reactive gas treating
• B01J 38/20 - Plural distinct oxidation stages
• B01J 37/00 - Processes, in general, for preparing catalystsProcesses, in general, for activation of catalysts
• B01D 53/94 - Chemical or biological purification of waste gases of engine exhaust gases by catalytic processes

Abstract

12341233 is selected from Q, H, W, L, P or R and X4 is selected from T, A, or V (SEQ ID NO:14) or the sequence SCHLPWASGL (SEQ ID NO:22). The neurological disorder can include those which would benefit from treatment through cognitive enhancement and/or neuroprotection, such as age-associated memory impairment or loss, mild cognitive impairment, and Alzheimer's disease, and can include Parkinson's disease, frontotemporal dementia, progressive supranuclear palsy, Pick's disease, corticobasal degeneration, alcoholic dementia, (DLB) dementia with Lewy bodies, Picks' disease, thalamic dementia, hippocampal sclerosis, Hallervorden-Spatz, multiple system atrophy, tauopathies, subacute aterioscleroitic encephalopathy (Binswanger's disease), amyloid angiopathy, vasculitis, prion diseases, and paraneoplastic syndromes. The invention also includes a pharmaceutical formulation for this method, which can include the peptide in the form of a cyclic peptide or a peptide conjugate.

IPC Classes  ?

• A61P 25/00 - Drugs for disorders of the nervous system
• C07K 14/575 - Hormones
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• C07K 7/64 - Cyclic peptides containing only normal peptide links
• A61P 25/16 - Anti-Parkinson drugs
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

A method comprises positioning a display screen of a mobile device and a surface of interest such that the display screen of the mobile device faces the surface of interest; emitting light by the display screen, wherein at least part of the emitted light is reflected by the surface of interest; receiving, by a camera of the mobile device, at least part of the light emitted by the display screen and reflected from the surface of interest thereby to generate at least one image; and processing the at least one image to determine at least one property of the surface of interest.

IPC Classes  ?

• G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
• G06K 9/20 - Image acquisition
• G06K 9/22 - Image acquisition using hand-held instruments
• G06K 9/46 - Extraction of features or characteristics of the image
• G06K 9/62 - Methods or arrangements for recognition using electronic means
• G06K 9/32 - Aligning or centering of the image pick-up or image-field

Goods & Services

[ Optical apparatus and instruments, namely optical inspection apparatus; microscopes; super-resolution microscopes; optical microscopes for use in revealing sub-cellular processes; biological microscopes; microscopes with single-pixel detection capability; microscopes for obtaining wide-field images within or through biological tissue; microscopic apparatus and instruments for use in research relating to cells, tissue and inert particles in the nature of microscope illuminating devices; microscopic apparatus and instruments, namely, biological microscopes for use in research relating to the biological sciences, drug discovery and early diagnosis of disease; optical microscopes for use in ophthalmology, neuroscience and developmental biology; optical microscopes for use in the analysis of cells, tissue, inert particles and turbid media; optical microscopes for use in the biological sciences, drug discovery and early diagnosis of disease; optical microscopes for use in the diagnosis of nephrotic disease; optical microscopes for use in the diagnosis of platelet granule disorders; replacement parts and fittings for all the aforesaid goods ] [ Medical apparatus and instruments for use in surgery; replacement parts and fittings for all the aforesaid goods ] Medical services; medical care; provision of medical information incorporating imaging data via microscopy; provision of medical information via microscopy; provision of medical information relating to the use of microscopes in the field of ophthalmology, neuroscience and developmental biology; provision of medical information relating to the use of optical microscopes in the medical analysis of cells, tissue, inert particles and turbid media; provision of medical information relating to the use of optical microscopes in the biological sciences, drug discovery and early diagnosis of disease

Abstract

The present disclosure describes a receiver (112) for a wireless optical communications system (110). The receiver (112) includes an optical element (116) for receiving an optical signal (114) including at least one spectral component. The optical element (116) spatially separates at least one spectral component from at least one other spectral component of the optical signal (114).

IPC Classes  ?

• H04B 10/114 - Indoor or close-range type systems
• H04B 10/116 - Visible light communication
• H04B 10/67 - Optical arrangements in the receiver
• H04B 10/60 - Receivers

Abstract

A security or identification device comprises a membrane laser structure configured to be optically pumped. The membrane laser structure comprises a flexible emission layer comprising a gain material; and one or more structures formed in or associated with the flexible emission layer and configured to provide optical feedback in the emission layer to produce a laser light output having at least one property representing an identifier.

IPC Classes  ?

• H01S 3/16 - Solid materials
• G07D 7/1205 - Testing spectral properties
• G06K 7/12 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using a selected wavelength, e.g. to sense red marks and ignore blue marks

Abstract

The present invention is based on the finding that the essential neural protein, neurochondrin (NCDN), interacts with the Survival Motor Neurone (SMN) protein. In neurodegenerative disorders, novel interactions such as this provide new insights into disease pathology and/or additional or alternate therapeutic options. Thus the disclosure provides neurochondrin (NCDN) modulators for use in the treatment and/or prevention of a neurodegenerative disorder.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
• A61P 25/16 - Anti-Parkinson drugs
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

A system for measuring a liquid sample comprising biological material, the system comprising an integrating light collector for collecting light and for at least partially containing the sample; a light source for introducing light in the integrating light collector; a signal generator or modulator configured to cause a known modulation of the light output by the light source; a phase-sensitive detector for detecting scattered light in the integrating light collector; at least one of an exit port to allow un-scattered light to exit the integrating light collector, a beam dump, or a baffle arranged to absorb unscattered light; and a processor configured to analyse the detected modulated light to determine changes in the detected modulated light as a function of time thereby to determine at least one of: drug susceptibility of the biological material; a change in a number of cells in the sample; a change in cell state; a change in the biological material.

IPC Classes  ?

• G01N 21/51 - Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
• G01N 21/47 - Scattering, i.e. diffuse reflection
• C12Q 1/18 - Testing for antimicrobial activity of a material
• C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
• G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
• G01J 3/433 - Modulation spectrometryDerivative spectrometry
• G01N 15/06 - Investigating concentration of particle suspensions
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
• G01N 21/03 - Cuvette constructions
• G01N 21/53 - Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
• G01N 15/02 - Investigating particle size or size distribution
• C12Q 1/06 - Quantitative determination
• G01N 15/00 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials
• G01N 21/11 - Filling or emptying of cuvettes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

A light sheet imaging system, such as a light sheet microscope, comprises an illumination arrangement for generating a light sheet for three-photon excitation of a fluorescent sample, and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam. A method of light sheet imaging comprises using a light sheet for three-photon excitation of a fluorescent sample, and collecting fluorescence generated in the sample as a result of three- photon excitation of the sample by the light sheet. Such a method may be used for light sheet microscopy.

IPC Classes  ?

• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

Disclosed are metal organic framework materials (MOFs), comprising an extra-framework NO releasing compound within the internal pores and/or channels of the MOF, the NO-releasing compounds and their preparation and uses. The MOFs and NO-releasing compounds are capable of releasing NO on application of an external stimulus and may provide materials with multiple modes of antibacterial and/or drug action.

IPC Classes  ?

• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 31/155 - Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (HN=C(OH)NH2), isothiourea (HN=C(SH)—NH2)
• A61K 47/52 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61K 9/14 - Particulate form, e.g. powders
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material

Abstract

An optical system comprising a randomizer that has a plurality of randomly positioned scatterers for scattering and thereby randomizing light to generate a speckle pattern and a detector for detecting the speckle pattern to determine at least one property of the light and/or change in at least one property of the light.

IPC Classes  ?

• G01J 9/02 - Measuring optical phase differenceDetermining degree of coherenceMeasuring optical wavelength by interferometric methods
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01J 4/00 - Measuring polarisation of light
• G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors
• G01J 1/04 - Optical or mechanical part

Abstract

A set of strings for a musical instrument comprising: at least a first and second string, wherein the first string comprises a core and a winding and the second string comprises at least a core; wherein each string is configured to be held at a selected tension in a musical instrument to produce a tone of a respective different desired pitch; and wherein at least one property of the cores and windings of one or both of the first and second strings is selected such that a change in pitch of the first string matches a change in pitch of the second string for a variation of the string tensions away from the selected tensions.

IPC Classes  ?

• G10D 3/10 - Strings

Abstract

A distributed feedback laser having a conjugated dendrimer as the active lasing component, and a method for patterning conjugated dendrimers.

IPC Classes  ?

• B29C 59/00 - Surface shaping, e.g. embossingApparatus therefor
• C08G 83/00 - Macromolecular compounds not provided for in groups
• H01S 5/36 - Structure or shape of the active regionMaterials used for the active region comprising organic materials
• H01S 5/04 - Processes or apparatus for excitation, e.g. pumping
• H01S 5/12 - Construction or shape of the optical resonator the resonator having a periodic structure, e.g. in distributed feedback [DFB] lasers
• B29C 59/02 - Surface shaping, e.g. embossingApparatus therefor by mechanical means, e.g. pressing

Abstract

An apparatus (150) comprises a first detection chamber (130) for receiving microorganisms and configured to allow detection of the microorganisms via detection of scattered light from the first detection chamber (130); a medium (120) configured to permit passage of microorganisms from a sample (110) through the medium (120) into the first detection chamber (130); and at least one second detection chamber (140) configured to allow detection of the microorganisms via detection of scattered light from the at least one second detection chamber (140).

IPC Classes  ?

• G01N 21/51 - Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
• G01N 15/06 - Investigating concentration of particle suspensions
• G01N 21/47 - Scattering, i.e. diffuse reflection
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01N 21/11 - Filling or emptying of cuvettes

Abstract

The invention relates to a catalyst useful in the steam reforming of hydrocarbons and oxygenated hydrocarbons. The invention provides a method for preparing a catalyst comprising heating a spinel of formula ANixFe(1-X)CrO4 where A is Mn or Mg and x is from 0 to 0.75 under reducing conditions at a temperature of from 800 to 1500 °C, and catalysts obtainable by said method.

IPC Classes  ?

• B01J 37/03 - PrecipitationCo-precipitation
• C01B 3/32 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of gaseous or liquid organic compounds with gasifying agents, e.g. water, carbon dioxide, air
• B01J 37/08 - Heat treatment
• B01J 37/16 - Reducing
• B01J 37/18 - Reducing with gases containing free hydrogen
• B01J 23/889 - Manganese, technetium or rhenium
• B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
• B01J 23/86 - Chromium
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 35/02 - Solids
• B01J 35/10 - Solids characterised by their surface properties or porosity

Abstract

An assembly comprising an illuminator and/or at least one camera, the assembly further comprising or being configured to connect to at least one side emitting optical fibre, wherein the at least one side emitting optical fibre is configured or configurable to receive at least some of the light from one or more light sources and transmit the light along at least part or all of the length of the at least one optical fibre.

IPC Classes  ?

• B63C 11/02 - Divers' equipment

Abstract

A method of manufacturing a platform (10) for an integrated electronic and optical circuit comprises forming at least one optical device portion in a CMOS compatible substrate (12), wherein the optical device portion comprises a waveguide layer (22) and a barrier layer (20) arranged to confine light to a region of the waveguide layer, wherein forming the at least one optical device potion comprises: forming at least one trench (14) in the substrate (12); depositing the barrier layer (20) in the at least one trench (14); depositing the waveguide layer (22) over the barrier layer (20), and planarizing the substrate (12).

IPC Classes  ?

• G02B 6/122 - Basic optical elements, e.g. light-guiding paths
• G02B 6/136 - Integrated optical circuits characterised by the manufacturing method by etching

Abstract

An optical system comprising trapping optics for forming an optical trap using counter propagating beams of light and light sheet imaging optics for light sheet imaging a particle, for example a cell, that is positioned in the optical trap, wherein the wavelength of the counter propagating beams of light and the wavelength of the light used for light sheet imaging are non-interfering.

IPC Classes  ?

• G02B 21/32 - Micromanipulators structurally combined with microscopes
• G21K 1/00 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
• G02B 21/00 - Microscopes
• G02B 21/06 - Means for illuminating specimen
• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes

Abstract

A light sheet imaging system comprises an acoustic trapping arrangement for forming an acoustic trap using one or more acoustic beams and an optical system for light sheet imaging a sample positioned in the acoustic trap. A light sheet imaging method comprises forming an acoustic trap using one or more acoustic beams and light sheet imaging a sample positioned in the acoustic trap. The system and/or the method may be used for light sheet microscopy using acoustic trapping for the contactless confinement of a sample to be imaged such as a particle, a colloid, a cell, a conglomerate of cells (e.g. a cell biopsy), an embryo, a larva or an organism such as a complex organism or a plurality of such samples.

IPC Classes  ?

• G02B 21/00 - Microscopes
• G02B 21/32 - Micromanipulators structurally combined with microscopes
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes

Abstract

The present disclosure provides novel adjuvants which may be used in combination with one or more antigens to augment, modulate or enhance a host immune response to the one or more antigens. The adjuvants are based on sialic acid binding molecules and may be combined with any type of antigen. The adjuvants may be formulated for mucosal and/or intranasal administration.

IPC Classes  ?

• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• C07K 14/28 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Vibrionaceae (F)
• C07K 14/315 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci

Abstract

The disclosure provides molecules with an affinity for (or an ability to bind to), sialic acid, for use in compositions, medicaments and methods for the treatment of sepsis, its symptoms and sepsis associated pathologies and immune responses.

IPC Classes  ?

• A61K 39/09 - Streptococcus
• C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

The present disclosure provides molecules which modulate cell growth. These molecules include those that bind sialic acid which may find application in the treatment and/or prevention of cell proliferation and/or differentiation disorders, cancer and/or it's migration and/or spread.

IPC Classes  ?

• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.

IPC Classes  ?

• A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
• C07F 15/04 - Nickel compounds
• C07F 1/10 - Silver compounds
• C07F 3/06 - Zinc compounds
• A01N 59/16 - Heavy metalsCompounds thereof
• C07F 1/00 - Compounds containing elements of Groups 1 or 11 of the Periodic Table
• C07C 51/41 - Preparation of salts of carboxylic acids by conversion of the acids or their salts into salts with the same carboxylic acid part
• A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
• A01N 37/40 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio-analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio-analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
• C07C 65/05 - Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids

Abstract

A Raman system (2) for use in performing Raman spectroscopy on a sample (4), comprises an optical source (8), a spectrometer (10), and an optical system (20, 22) for coupling light from the optical source and to the sample and for coupling light from the sample to the spectrometer. The optical system may be configured for coupling light from the optical source and a further optical source (8a) to the sample and for coupling light from the sample to the spectrometer and a further spectrometer (10a). The Raman system may be portable and/ or may be configured to be transported and/or carried and/or may be handheld.

IPC Classes  ?

• G01J 3/44 - Raman spectrometryScattering spectrometry
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01N 21/65 - Raman scattering

Abstract

A method of processing a lignocellulosic feedstock includes heating the lignocellulosic feedstock in a solvent mixture comprising an acid and at least 80% by volume of n-butanol to produce a reaction mixture including a butylated lignin. A butylated lignin product wherein at least 85% of the β-Ο-4 linkages include n-butyl ether groups can be prepared. Cellulose and butylated hemicellulose products can also be obtained.

IPC Classes  ?

• C07G 1/00 - Low-molecular-weight derivatives of lignin
• C08H 7/00 - LigninModified ligninHigh-molecular-weight products derived therefrom

Abstract

A system for measuring a sample comprising: an integrating sphere light collector (12) for collecting light and containing the sample; a light source (24) for introducing light in the integrating sphere light collector (12), wherein the light source (24) is operable to output light with a known modulation, preferably by using a signal generator (26); a detector (22) for detecting scattered light in the integrating sphere light collector (12) and generating a signal indicative of the scattered light, and a lock-in amplifier (28) operable use the known light modulation and the signal generated by the detector (22) to provide an output for analysis.

IPC Classes  ?

• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01N 21/47 - Scattering, i.e. diffuse reflection
• G01N 21/51 - Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
• G01J 3/433 - Modulation spectrometryDerivative spectrometry
• G01N 15/06 - Investigating concentration of particle suspensions
• G01N 21/03 - Cuvette constructions
• G01N 21/53 - Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
• G01N 15/02 - Investigating particle size or size distribution
• C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
• C12Q 1/06 - Quantitative determination
• C12Q 1/18 - Testing for antimicrobial activity of a material
• G01N 15/00 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials
• G01N 21/11 - Filling or emptying of cuvettes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

A receiver assembly (100) and data communications method are disclosed. In one arrangement, a receiver assembly (100) comprises a concentration stage (14). The concentration stage (14) receives radiation via an input surface (120) and outputs concentrated radiation via an output surface (122). The concentration stage comprises a wavelength converting member (6) that converts radiation to longer wavelength radiation. An optical element (102) is provided which is such that if a plane wave of radiation is incident on the optical element a spatial distribution of radiation derived from the plane wave on the input surface of the concentration stage varies as a function of a direction of incidence of the plane wave relative to the optical element. A plurality of detectors (42) are provided, each detecting radiation output from a different portion of the output surface of the concentration stage.

IPC Classes  ?

• H01L 31/0232 - Optical elements or arrangements associated with the device
• H04B 10/116 - Visible light communication
• H04B 10/67 - Optical arrangements in the receiver

Abstract

The invention relates to a method of producing electrode materials for solid oxide cells which comprises applying an electric potential to a metal oxide which has a perovskite crystal structure. The resultant electrode catalyst exhibits excellent electrochemical performance. The invention extends to the electrode catalyst itself, and to electrodes and solid oxide cells comprising the electrode catalyst.

IPC Classes  ?

• H01M 8/1213 - Fuel cells with solid electrolytes operating at high temperature, e.g. with stabilised ZrO2 electrolyte characterised by the electrode/electrolyte combination or the supporting material
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 4/88 - Processes of manufacture
• B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
• H01M 8/12 - Fuel cells with solid electrolytes operating at high temperature, e.g. with stabilised ZrO2 electrolyte

Abstract

An etchant is described that includes an N-heterocyclic carbene and optionally an appropriate solvent. The etchant was effective at etching a metallic surface having, for example, a metal oxide and/or metal, in both solution phase and vapour-phase. The etchant has been shown to effectively etch oxidized copper and tungsten.

IPC Classes  ?

• C23F 1/10 - Etching compositions

Abstract

An etchant is described that includes an N-heterocyclic carbene and optionally an appropriate solvent. The etchant was effective at etching a metallic surface having, for example, a metal oxide and/or metal, in both solution phase and vapour-phase. The etchant has been shown to effectively etch oxidized copper and tungsten.

IPC Classes  ?

• C23F 1/10 - Etching compositions

Abstract

A system for measuring cellular forces exerted on a surface comprising: a deformable sensor that has a deformable surface adapted to deform on application of a cellular force, and an optical detector for optically detecting deformation of the surface.

IPC Classes  ?

• G01N 33/483 - Physical analysis of biological material
• G01N 13/00 - Investigating surface or boundary effects, e.g. wetting powerInvestigating diffusion effectsAnalysing materials by determining surface, boundary, or diffusion effects
• G01L 5/00 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes
• G01L 1/24 - Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis

Abstract

A method of depolymerizing a lignin includes oxidizing the lignin to provide an oxidized lignin wherein benzylic —OH of β-O-4 linkages have been converted to carbonyl. The oxidized lignin is depolymerized with a metal selected from the group consisting of zinc, magnesium, aluminum and titanium or mixtures thereof, in the presence of an ammonium salt or carbon dioxide. Also described are methods for manufacturing phenolic products from lignin and a method for the cleavage of a β-O-4 linkage in a substrate.

IPC Classes  ?

• C07B 41/06 - Formation or introduction of functional groups containing oxygen of carbonyl groups
• C07G 1/00 - Low-molecular-weight derivatives of lignin
• D21C 11/00 - Regeneration of pulp liquors
• C07B 41/02 - Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
• C07C 39/10 - Polyhydroxy benzenesAlkylated derivatives thereof

Abstract

A method of minimizing cross-talk between optical modes propagating in a multi-mode optical fiber, comprises superimposing a plurality of optical wavefunctions; determining a relationship between superpositions of at least some of the optical wavefunctions and at least one measure of orthogonality of the optical modes at an output of the multi-mode optical fiber; and identifying a superposition of at least some of the optical wavefunctions that provides a desired or optimized value of the at least one measure of orthogonality using the determined relationship. The method further comprises generating, using light from a laser and at least one optical component, the identified superposition of at least some of the optical wavefunctions that provides the desired or optimized value of the at least one measure of orthogonality.

IPC Classes  ?

• G02B 27/58 - Optics for apodization or superresolutionOptical synthetic aperture systems

Abstract

The invention provides a catalyst comprising iron oxide, nickel, ceria or palladium supported on stainless steel foam. The catalyst is effective in oxidising aromatic compounds such as toluene and o-cresol and, advantageously, is particularly effective when the oxidation is carried out at elevated temperatures that correspond to temperatures attained in areas of the aircraft where cabin air is recirculated.

IPC Classes  ?

• B01J 37/02 - Impregnation, coating or precipitation
• B01J 23/10 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of rare earths
• B01J 23/44 - Palladium
• B01D 53/86 - Catalytic processes
• B01J 23/745 - Iron
• B01J 23/755 - Nickel
• B01J 35/02 - Solids
• B01J 35/04 - Foraminous structures, sieves, grids, honeycombs
• B01J 35/10 - Solids characterised by their surface properties or porosity

Abstract

A chirp generator comprises a direct digital synthesiser operable to generate a frequency chirp, wherein the frequency chirp is restricted to span less than one octave, a carrier signal that has a higher frequency than the frequency chirp, a mixer for mixing the frequency chirp and the carrier signal to produce a signal that has a lower sideband that has a rising frequency response and an upper sideband that has a falling frequency response, a filter for selecting one of the sidebands and rejecting the other sideband, and at least one component that has a frequency response that compensates for the frequency response of the selected sideband thereby to provide a substantially flat frequency chirp.

IPC Classes  ?

• G01S 7/35 - Details of non-pulse systems
• G01S 13/34 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated using transmission of continuous, frequency-modulated waves while heterodyning the received signal, or a signal derived therefrom, with a locally-generated signal related to the contemporaneously transmitted signal

Abstract

An optical system for generating an Airy beam light sheet comprising an optical arrangement for generating a Gaussian beam, and an optical element for converting the Gaussian beam into an Airy beam light sheet, wherein a single optical element is provided for converting the Gaussian beam into an Airy beam light sheet.

IPC Classes  ?

• G02B 26/00 - Optical devices or arrangements for the control of light using movable or deformable optical elements
• G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
• G02B 21/06 - Means for illuminating specimen
• G02B 21/00 - Microscopes
• G02B 26/06 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the phase of light
• G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for
• G02B 26/02 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the intensity of light
• G02B 27/30 - Collimators

Abstract

Organic thermally activated delayed fluorescence (TADF) species according to Formula I are described. The species have donor (D) and acceptor (A) moieties bonded to a ring system (Q). Q is an unsaturated carbocyclic or heterocyclic ring system including at least two rings fused together. The ring system Q may include at least one polyunsaturated ring, typically an aromatic or heteroaromatic ring. A polyunsaturated ring includes at least two double bonds. The ring system Q may include at least one benzene ring fused to at least one other ring. Both the at least two rings fused together in ring system Q may be aromatic and/or heteroaromatic rings. The ring system Q may be an annelated benzene or annelated heteroarene ring system.

IPC Classes  ?

• H01L 51/54 - Selection of materials

Abstract

A contact lens or visual prosthesis that includes at least one array or distribution of optical elements on a flexible substrate, the optical elements in the array or distribution being separated by or having a periodicity of less than 1 micron and each element having a dimension of 1 micron or less.

IPC Classes  ?

• G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
• G02C 7/02 - LensesLens systems
• G02C 7/04 - Contact lenses for the eyes
• A61F 2/16 - Intraocular lenses

Abstract

A Raman spectroscopic detection device comprising at least one microfluidic sample channel; at least one excitation waveguide for exciting a Raman signal and at least one collection waveguide for collecting a Raman signal. The output of the excitation waveguide and the input of the collection waveguide are positioned directly in the microfluidic sample channel.

IPC Classes  ?

• G01N 33/14 - Beverages
• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/05 - Flow-through cuvettes
• G01N 21/65 - Raman scattering
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details

Goods & Services

Apparatus for recording, transmission or reproduction of sound or images; magnetic data carriers, recording discs; compact discs; DVDs; recorded discs; encoded cards; computer games; video game software; computer and video games programmes; video discs; electric and electronic communication apparatus; recorded video discs and video tapes; computer peripherals; optical apparatus and instruments; computers; computer software; computer software and publications in electronic form supplied on-line from databases or from facilities provided on the Internet (including websites); computer software and telecommunications apparatus (including modems) to enable connection to databases and the Internet; computer software to enable searching of data; smart cards; encoded cards and cards bearing machine readable information; CD-ROMs; cases for photographic apparatus; calculators; telephones; covers, fascias and cases for mobile phones, accessories for mobile phones; phone cards; sunglasses and cases for sunglasses; spectacles; contact lenses; cases for spectacles and contact lenses; audio visual teaching apparatus; screensavers; credit cards; encoded cards; smart cards; bank cards; debit cards; cash cards; computer mouse, computer mouse mats; gum guards; gum guards for protection in sport; gum shields; gum shields for protection in sport; protective clothing; body armour for the protection of various parts of the body for use in sports activities; protective headwear for the prevention of accidents and injury; protective helmets; protective helmets for use in sports; protective gloves; face protectors; magnets; decorative magnets; identification labels (encoded or magnetic); electronic labels containing coded information; self adhesive labels (encoded or magnetic). Jewellery; earrings; rings and pendants; jewellery in the nature of fobs, ingots and chains; cuff-links; badges of precious metals; tie-pins; tie slides; heraldic crests for use as jewellery; silver and gold tankards; keyrings; precious metals and their alloys and goods in precious metals or coated therewith; precious stones; horological and chronometric instruments; watches; ornaments; works of art of precious metals; statuettes of precious metal; stopwatches; chains; watch chains and watch cases; clocks; goods of silver and gold, in this class; watch straps. Paper, cardboard; printed matter; book binding materials; photographs; stationery; pens, pencils and writing instruments; erasers; rulers; posters; notebooks; notepads; diaries; calendars; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching materials (except apparatus); printing blocks; printed publications; books; periodical publications, magazines, brochures, event programmes, booklets, catalogues, guides, pamphlets, news-sheets and circulars; document holders; personal organisers; cards; instructional and teaching material. Leather and imitations of leather, and goods made of these materials and not included in other classes; animal skins, hides; trunks and travelling bags; umbrellas, parasols and walking sticks; whips, harness and saddlery; bags; backpacks; gym sacks; wallets, sports bags; holdalls; school bags; luggage; handbags; shoulder bags; waist bags; rucksacks; vanity cases; overnight bags; duffle bags; garment bags for travel; purses; card cases, key cases and notecases; cases of leather or of leather board; leather laces; boot bags; suit carriers; shoe bags; business card cases. China, chinaware; glassware; porcelain; earthenware; pottery; crystal glassware; cups; mugs; bowls; trays; dishes; plates; coasters; figurines, statues and statuettes of porcelain, ceramic, earthenware or glass; jars; jugs; money boxes; tableware; hairbrushes; combs; wastepaper baskets; vases; cups of precious metal. Clothing, footwear, headgear; baseball caps; scarves; jackets, sweatshirts, polo shirts, t-shirts, hoodies, rugby shirts, waterproof jackets, shower proof jackets; sports clothing; track suits; jogging pants; sports tops and sports shorts; sports socks; ladies wear; sports shirts; clothing for wear during exercise; training jerseys and training shorts; articles of outerwear; clothing of leather and of imitation leather; belts; ties, bow ties, pullovers, trousers, socks, skirts, dresses, sweaters, pants, jerseys, jumpers, waistcoats, kilts, pyjama suits, night suits, night shirts, night dresses, dressing robes; underwear; boxer shorts; blazers, coats, fleece tops; leisure suits; sports jerseys; football tops, football shorts, bikinis, swimming trunks, beachwear; waterproof clothing; waxed jackets, wet suits; training shoes, boots, football boots. Business administration services; office function services; business management services; advertising services; dissemination of advertising material and matter; public relation services; database management services; business research services; conducting, organising and arranging of exhibitions for commercial and advertising purposes; information and advisory services relating to all the aforesaid services. University services; academic education, instruction and training in the fields of the arts and humanities, the social, physical, biological and medical sciences, technology, law, agriculture, veterinary sciences, industry and technology; provision of educational, instructional and training courses; information services relating to education; education instruction courses provided from a computer network or via the Internet; educational examination services; provision of training workshops; conducting, organising and arranging conferences, seminars and exhibitions; education information and library services; museum services; provision of sports and recreational facilities; entertainment; sporting and cultural activities; organisation of sporting events and activities; sporting services; recreational services; hospitality services (entertainment); organising of entertainment and social events; organisation and conducting of musical concerts; museum services; club services; health club services; presentation of live performances; publishing services, physical education, training, sport camp services, education relating to sports and leisure, organisation of sporting competitions, film production, provision of exhibition and museum facilities, rental of sports apparatus, photography services; provision of entertainment, education and information services relating to education provided from a database, computer network or via the Internet; production and rental of educational instruction materials; providing on-line electronic publications (not downloadable); publication of texts, books, pamphlets, magazines and of electronic books and journals online; professional consulting services in the fields of academic education; professional consultancy relating to education; provision of information, consultancy and advisory services relating to any of the aforesaid services. Research and development services; technical research; technical research services and development of new products and new technology for others in the fields of optoelectronics, lasers, semi-conductors, fibreoptics, petroleum, geology, marine and ocean systems, the environment, microelectronics, materials and material testing, engineering and physics, computing and computer programming, biotechnology and biological science, information and knowledge systems, chemistry and pharmaceuticals, logistics, economics, actuarial services, maths and languages, language translation and interpretation; scientific research services and consultancy related thereto in the fields of the arts and humanities, the social, physical, biological and medical sciences, technology, engineering and computing; provision of any of the services mentioned in this class and information related thereto via a website; information provided online from a computer database or from the Internet relating to any of the aforesaid services; creating and maintaining web-sites; hosting web-sites of others; computer programming and computer software services; material testing services; industrial design services; information, consultancy and advisory services relating to any and all of the aforesaid services. Provision of temporary accommodation; catering for the provision of food and drink; arranging and booking of accommodation for travellers; hospitality services (food and drink, accommodation); catering services for hospitality suites; rental of meeting rooms; catering; restaurants; cafeterias; snack-bars; bistros; bars; canteens; self service restaurants. Intellectual property consultancy and licensing of intellectual property; exploitation of patents by licensing; legal services.

Goods & Services

Apparatus for recording, transmission or reproduction of sound or images; magnetic data carriers, recording discs; compact discs; DVDs; recorded discs; encoded cards; computer games; video game software; computer and video games programmes; video discs; electric and electronic communication apparatus; recorded video discs and video tapes; computer peripherals; optical apparatus and instruments; computers; computer software; computer software and publications in electronic form supplied on-line from databases or from facilities provided on the Internet (including websites); computer software and telecommunications apparatus (including modems) to enable connection to databases and the Internet; computer software to enable searching of data; smart cards; encoded cards and cards bearing machine readable information; CD-ROMs; cases for photographic apparatus; calculators; telephones; covers, fascias and cases for mobile phones, accessories for mobile phones; phone cards; sunglasses and cases for sunglasses; spectacles; contact lenses; cases for spectacles and contact lenses; audio visual teaching apparatus; screensavers; credit cards; encoded cards; smart cards; bank cards; debit cards; cash cards; computer mouse, computer mouse mats; gum guards; gum guards for protection in sport; gum shields; gum shields for protection in sport; protective clothing; body armour for the protection of various parts of the body for use in sports activities; protective headwear for the prevention of accidents and injury; protective helmets; protective helmets for use in sports; protective gloves; face protectors; magnets; decorative magnets; identification labels (encoded or magnetic); electronic labels containing coded information; self adhesive labels (encoded or magnetic). Jewellery; earrings; rings and pendants; jewellery in the nature of fobs, ingots and chains; cuff-links; badges of precious metals; tie-pins; tie slides; heraldic crests for use as jewellery; silver and gold tankards; keyrings; precious metals and their alloys and goods in precious metals or coated therewith; precious stones; horological and chronometric instruments; watches; ornaments; works of art of precious metals; statuettes of precious metal; stopwatches; chains; watch chains and watch cases; clocks; goods of silver and gold, in this class; watch straps. Paper, cardboard; printed matter; book binding materials; photographs; stationery; pens, pencils and writing instruments; erasers; rulers; posters; notebooks; notepads; diaries; calendars; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching materials (except apparatus); printing blocks; printed publications; books; periodical publications, magazines, brochures, event programmes, booklets, catalogues, guides, pamphlets, news-sheets and circulars; document holders; personal organisers; cards; instructional and teaching material. Leather and imitations of leather, and goods made of these materials and not included in other classes; animal skins, hides; trunks and travelling bags; umbrellas, parasols and walking sticks; whips, harness and saddlery; bags; backpacks; gym sacks; wallets, sports bags; holdalls; school bags; luggage; handbags; shoulder bags; waist bags; rucksacks; vanity cases; overnight bags; duffle bags; garment bags for travel; purses; card cases, key cases and notecases; cases of leather or of leather board; leather laces; boot bags; suit carriers; shoe bags; business card cases. China, chinaware; glassware; porcelain; earthenware; pottery; crystal glassware; cups; mugs; bowls; trays; dishes; plates; coasters; figurines, statues and statuettes of porcelain, ceramic, earthenware or glass; jars; jugs; money boxes; tableware; hairbrushes; combs; wastepaper baskets; vases; cups of precious metal. Clothing, footwear, headgear; baseball caps; scarves; jackets, sweatshirts, polo shirts, t-shirts, hoodies, rugby shirts, waterproof jackets, shower proof jackets; sports clothing; track suits; jogging pants; sports tops and sports shorts; sports socks; ladies wear; sports shirts; clothing for wear during exercise; training jerseys and training shorts; articles of outerwear; clothing of leather and of imitation leather; belts; ties, bow ties, pullovers, trousers, socks, skirts, dresses, sweaters, pants, jerseys, jumpers, waistcoats, kilts, pyjama suits, night suits, night shirts, night dresses, dressing robes; underwear; boxer shorts; blazers, coats, fleece tops; leisure suits; sports jerseys; football tops, football shorts, bikinis, swimming trunks, beachwear; waterproof clothing; waxed jackets, wet suits; training shoes, boots, football boots. Business administration services; office function services; business management services; advertising services; dissemination of advertising material and matter; public relation services; database management services; business research services; conducting, organising and arranging of exhibitions for commercial and advertising purposes; information and advisory services relating to all the aforesaid services. University services; academic education, instruction and training in the fields of the arts and humanities, the social, physical, biological and medical sciences, technology, law, agriculture, veterinary sciences, industry and technology; provision of educational, instructional and training courses; information services relating to education; education instruction courses provided from a computer network or via the Internet; educational examination services; provision of training workshops; conducting, organising and arranging conferences, seminars and exhibitions; education information and library services; museum services; provision of sports and recreational facilities; entertainment; sporting and cultural activities; organisation of sporting events and activities; sporting services; recreational services; hospitality services (entertainment); organising of entertainment and social events; organisation and conducting of musical concerts; museum services; club services; health club services; presentation of live performances; publishing services, physical education, training, sport camp services, education relating to sports and leisure, organisation of sporting competitions, film production, provision of exhibition and museum facilities, rental of sports apparatus, photography services; provision of entertainment, education and information services relating to education provided from a database, computer network or via the Internet; production and rental of educational instruction materials; providing on-line electronic publications (not downloadable); publication of texts, books, pamphlets, magazines and of electronic books and journals online; professional consulting services in the fields of academic education; professional consultancy relating to education; provision of information, consultancy and advisory services relating to any of the aforesaid services. Research and development services; technical research; technical research services and development of new products and new technology for others in the fields of optoelectronics, lasers, semi-conductors, fibreoptics, petroleum, geology, marine and ocean systems, the environment, microelectronics, materials and material testing, engineering and physics, computing and computer programming, biotechnology and biological science, information and knowledge systems, chemistry and pharmaceuticals, logistics, economics, actuarial services, maths and languages, language translation and interpretation; scientific research services and consultancy related thereto in the fields of the arts and humanities, the social, physical, biological and medical sciences, technology, engineering and computing; provision of any of the services mentioned in this class and information related thereto via a website; information provided online from a computer database or from the Internet relating to any of the aforesaid services; creating and maintaining web-sites; hosting web-sites of others; computer programming and computer software services; material testing services; industrial design services; information, consultancy and advisory services relating to any and all of the aforesaid services. Provision of temporary accommodation; catering for the provision of food and drink; arranging and booking of accommodation for travellers; hospitality services (food and drink, accommodation); catering services for hospitality suites; rental of meeting rooms; catering; restaurants; cafeterias; snack-bars; bistros; bars; canteens; self service restaurants. Intellectual property consultancy and licensing of intellectual property; exploitation of patents by licensing; legal services.

Goods & Services

Apparatus for recording, transmission or reproduction of sound or images; magnetic data carriers, recording discs; compact discs; DVDs; recorded discs; encoded cards; computer games; video game software; computer and video games programmes; video discs; electric and electronic communication apparatus; recorded video discs and video tapes; computer peripherals; optical apparatus and instruments; computers; computer software; computer software and publications in electronic form supplied on-line from databases or from facilities provided on the Internet (including websites); computer software and telecommunications apparatus (including modems) to enable connection to databases and the Internet; computer software to enable searching of data; smart cards; encoded cards and cards bearing machine readable information; CD-ROMs; cases for photographic apparatus; calculators; telephones; covers, fascias and cases for mobile phones, accessories for mobile phones; phone cards; sunglasses and cases for sunglasses; spectacles; contact lenses; cases for spectacles and contact lenses; audio visual teaching apparatus; screensavers; credit cards; encoded cards; smart cards; bank cards; debit cards; cash cards; computer mouse, computer mouse mats; gum guards; gum guards for protection in sport; gum shields; gum shields for protection in sport; protective clothing; body armour for the protection of various parts of the body for use in sports activities; protective headwear for the prevention of accidents and injury; protective helmets; protective helmets for use in sports; protective gloves; face protectors; magnets; decorative magnets; identification labels (encoded or magnetic); electronic labels containing coded information; self adhesive labels (encoded or magnetic). Jewellery; earrings; rings and pendants; jewellery in the nature of fobs, ingots and chains; cuff-links; badges of precious metals; tie-pins; tie slides; heraldic crests for use as jewellery; silver and gold tankards; keyrings; precious metals and their alloys and goods in precious metals or coated therewith; precious stones; horological and chronometric instruments; watches; ornaments; works of art of precious metals; statuettes of precious metal; stopwatches; chains; watch chains and watch cases; clocks; goods of silver and gold, in this class; watch straps. Paper, cardboard; printed matter; book binding materials; photographs; stationery; pens, pencils and writing instruments; erasers; rulers; posters; notebooks; notepads; diaries; calendars; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching materials (except apparatus); printing blocks; printed publications; books; periodical publications, magazines, brochures, event programmes, booklets, catalogues, guides, pamphlets, news-sheets and circulars; document holders; personal organisers; cards; instructional and teaching material. Leather and imitations of leather, and goods made of these materials and not included in other classes; animal skins, hides; trunks and travelling bags; umbrellas, parasols and walking sticks; whips, harness and saddlery; bags; backpacks; gym sacks; wallets, sports bags; holdalls; school bags; luggage; handbags; shoulder bags; waist bags; rucksacks; vanity cases; overnight bags; duffle bags; garment bags for travel; purses; card cases, key cases and notecases; cases of leather or of leather board; leather laces; boot bags; suit carriers; shoe bags; business card cases. China, chinaware; glassware; porcelain; earthenware; pottery; crystal glassware; cups; mugs; bowls; trays; dishes; plates; coasters; figurines, statues and statuettes of porcelain, ceramic, earthenware or glass; jars; jugs; money boxes; tableware; hairbrushes; combs; wastepaper baskets; vases; cups of precious metal. Clothing, footwear, headgear; baseball caps; scarves; jackets, sweatshirts, polo shirts, t-shirts, hoodies, rugby shirts, waterproof jackets, shower proof jackets; sports clothing; track suits; jogging pants; sports tops and sports shorts; sports socks; ladies wear; sports shirts; clothing for wear during exercise; training jerseys and training shorts; articles of outerwear; clothing of leather and of imitation leather; belts; ties, bow ties, pullovers, trousers, socks, skirts, dresses, sweaters, pants, jerseys, jumpers, waistcoats, kilts, pyjama suits, night suits, night shirts, night dresses, dressing robes; underwear; boxer shorts; blazers, coats, fleece tops; leisure suits; sports jerseys; football tops, football shorts, bikinis, swimming trunks, beachwear; waterproof clothing; waxed jackets, wet suits; training shoes, boots, football boots. Business administration services; office function services; business management services; advertising services; dissemination of advertising material and matter; public relation services; database management services; business research services; conducting, organising and arranging of exhibitions for commercial and advertising purposes; information and advisory services relating to all the aforesaid services. University services; academic education, instruction and training in the fields of the arts and humanities, the social, physical, biological and medical sciences, technology, law, agriculture, veterinary sciences, industry and technology; provision of educational, instructional and training courses; information services relating to education; education instruction courses provided from a computer network or via the Internet; educational examination services; provision of training workshops; conducting, organising and arranging conferences, seminars and exhibitions; education information and library services; museum services; provision of sports and recreational facilities; entertainment; sporting and cultural activities; organisation of sporting events and activities; sporting services; recreational services; hospitality services (entertainment); organising of entertainment and social events; organisation and conducting of musical concerts; museum services; club services; health club services; presentation of live performances; publishing services, physical education, training, sport camp services, education relating to sports and leisure, organisation of sporting competitions, film production, provision of exhibition and museum facilities, rental of sports apparatus, photography services; provision of entertainment, education and information services relating to education provided from a database, computer network or via the Internet; production and rental of educational instruction materials; providing on-line electronic publications (not downloadable); publication of texts, books, pamphlets, magazines and of electronic books and journals online; professional consulting services in the fields of academic education; professional consultancy relating to education; provision of information, consultancy and advisory services relating to any of the aforesaid services. Research and development services; technical research; technical research services and development of new products and new technology for others in the fields of optoelectronics, lasers, semi-conductors, fibreoptics, petroleum, geology, marine and ocean systems, the environment, microelectronics, materials and material testing, engineering and physics, computing and computer programming, biotechnology and biological science, information and knowledge systems, chemistry and pharmaceuticals, logistics, economics, actuarial services, maths and languages, language translation and interpretation; scientific research services and consultancy related thereto in the fields of the arts and humanities, the social, physical, biological and medical sciences, technology, engineering and computing; provision of any of the services mentioned in this class and information related thereto via a website; information provided online from a computer database or from the Internet relating to any of the aforesaid services; creating and maintaining web-sites; hosting web-sites of others; computer programming and computer software services; material testing services; industrial design services; information, consultancy and advisory services relating to any and all of the aforesaid services. Provision of temporary accommodation; catering for the provision of food and drink; arranging and booking of accommodation for travellers; hospitality services (food and drink; accommodation); catering services for hospitality suites; rental of meeting rooms; catering; restaurants; cafeterias; snack-bars; bistros; bars; canteens; self service restaurants. Intellectual property consultancy and licensing of intellectual property; exploitation of patents by licensing; legal services.

Abstract

The present invention is based on the finding that in addition to interfering with or blocking, preventing and/or inhibiting the interaction between a pathogen and, for example, a sialic acid containing cell surface receptor, certain sialic acid binding molecules have immunomodulatory properties. The invention provides methods and uses which exploit sialic acid binding molecules in the treatment and/or prevention of disease by modulation and/or priming of the host immune response.

IPC Classes  ?

• A61K 39/07 - Bacillus
• A61K 39/09 - Streptococcus
• A61K 39/104 - Pseudomonas
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 39/02 - Bacterial antigens
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

An optical system comprising trapping optics for forming an optical trap using counter propagating beams of light and light sheet imaging optics for light sheet imaging a particle, for example a cell, that is positioned in the optical trap, wherein the wavelength of the counter propagating beams of light and the wavelength of the light used for light sheet imaging are non-interfering.

IPC Classes  ?

• G02B 21/00 - Microscopes
• G02B 21/06 - Means for illuminating specimen
• G02B 21/32 - Micromanipulators structurally combined with microscopes
• G21K 1/00 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating