An example method to alter one or more functional properties of food proteins includes inserting an amount of a food comprising one or more food proteins into a mixing chamber for processing. The mixing chamber includes an interior surface having an electrically conducting material contacting at least a portion of the amount of the food. The method also includes discharging an electric charge to the interior surface of the mixing chamber. The method further includes processing the food in the mixing chamber while the electric charge is discharged to the interior surface of the mixing chamber.
A system includes memory configured to store a database comprising produce temperature information corresponding to a produce quality, for example for the same or similar produce, and which may relate to produce quality over time. The system also includes a thermal imaging device configured to capture an image of produce and a processor operatively coupled to the memory and the thermal imaging device. The processor is configured to receive the image of the produce, determine a temperature of the produce based on the received image, and determine a quality of the produce based on a comparison of the temperature of the produce to the produce temperature information stored in the database.
The present technology provides liquid quality assessment systems and methods for their preparation and use. The systems can include a light source configured to illuminate a liquid sample, a reflecting surface configured to reflect light scattered by the liquid sample, and a detector configured to detect light intensity, wherein the light source illuminates the liquid sample with a first incident light when the reflecting surface is absent; the detector detects a first light scattered by the liquid sample in response to the first incident light; the light source illuminates the liquid sample with a second incident light when the reflecting surface is present; and the detector detects a second light which is a combination of light scattered by the liquid sample in response to the second incident light and light reflected by the reflecting surface of light scattered by the liquid sample in response to the second incident light.
Technologies are generally described herein generally relate to tunnel field-effect transistor (TFETs) structures with a gate-on-germanium source (GoGeS) on bulk silicon substrate for sub 0.5V (VDD) operations. In some examples, the GoGeS structure may include an increase in tunneling area and, thereby, a corresponding increases in the ON-state current ION. In order to achieve supersteep sub-threshold swing, both the lateral tunneling due to gate electric-field and the non-uniform tunneling at the gate-edge due to field-induced barrier lowering (FIBL) may be suppressed through selection of component dimension in the device structure. Example devices may be fabricated using CMOS fabrication technologies with the addition of selective etching in the process flow.
H01L 29/08 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions with semiconductor regions connected to an electrode carrying current to be rectified, amplified, or switched and such electrode being part of a semiconductor device which comprises three or more electrodes
6.
METHODS OF PRODUCING VANADIUM BORIDE AND USES THEREOF
Described herein are methods of producing metal borides including, but not limited to vanadium boride from metal ores and iron slag. Also disclosed are methods of producing vanadium boride in situ from titaniferous magnetite ore or iron slag and uses for vanadium boride.
Methods of synthesizing metal nanoparticles from a metal oxide ore are provided. The methods include adding a metal compound and a reducing agent to the metal oxide ore and contacting the metal compound and the reducing agent to form zero-valent metal nanoparticles. The methods also include contacting the metal oxide ore and hydrogen (H2) in presence of the zero-valent metal nanoparticles to form zero-valent metal and metal nanoparticles.
A62D 3/37 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by reduction, e.g. hydrogenation
8.
STABILIZED LACCASE ENZYME AND METHODS OF MAKING AND USING THE SAME
Provided herein are compositions and methods for enhancing enzyme activity, half-life, thermostability, enhanced activity at elevated temperature, and/or decreasing the pH dependency of laccase enzyme. Also provided are methods for using the composition comprising the stabilized enzymes.
Technologies are generally provided for converting a k-ary tree to an equivalent height balanced binary tree. A k-ary tree root may be first set as the binary tree root. Nodes may then be inserted in the binary tree based on nodes of the k-ary tree. First two children of each k-ary tree node may be inserted as left and right children in the binary tree. If there are additional children, those may be inserted into a child queue. If there are less than two children in the k-ary tree, children from the child queue may be used to fill the left and right child nodes in the equivalent binary tree repeating the process level-wise until all nodes in the k-ary tree are processed.
Methods including contacting, in the solid state, a sample comprising a first organic molecule with a composition comprising a carbon nanotube, such that an interface forms between the sample and the composition; observing any movement of the interface; and characterizing the first organic molecule based On the observed movement are described.
Exposure to a static magnetic field changes the fluorescence intensity of a wide range of fluorophores, including small molecules (e.g., tryptophan), complex organizations of fluorophores (e.g., proteins), quantum dots, nanoparticles, and other materials. Different materials may experience different changes in fluorescence emission upon exposure to a magnetic field— for instance, some or all of a material's fluorescence emission spectrum may increase in amplitude or shift in wavelength. Different materials may also experience different changes in relaxation time, which is the time constant associated with fluorescence decay. These magnetically induced differences fluorescence emission spectra and decay can be used to identify, classify, or sort materials noninvasively.
A technique for determining whether or not a fluorescent material exhibits a directionally dependent property, such as anisotropy or chirality, involves illuminating the particle at its excitation wavelength to stimulate fluorescent emission at both a full-frequency (fundamental) wavelength and a half-frequency wavelength. The ratio of the full-frequency signal strength to the half-frequency signal strength provides an indication of the sample's directionally dependent property. This half-frequency spectral analysis can be used to sort anisotropic particles suspended in fluid flowing through a flow cytometer. For instance, the present technique may be used to separate racemic mixtures of chiral enantiomers of cells, pharmaceutical compounds, and other samples.
Embodiments described herein provide for nanofertilizers having at least one plant nutrient coated onto a metal nanoparticle. Some embodiments provide for a method of making a nanofertilizer including providing a metal nanoparticle and coating the metal nanoparticle with at least one plant nutrient or precursor thereof. In some embodiments, a method of making a nanofertilizer may include mixing a metal salt and a plant nutrient in an aqueous medium to form a solution and adding a reducing agent to the solution to form a coated metal nanoparticle. Some embodiments provide for a boron nanofertilizer and methods of making the same. Some embodiments provide for a method of treating a plant nutrient deficiency, such as, for example, a boron deficiency. Some embodiments also provide for a kit for making a plant nutrient coated nanoparticle.
Provided herein are compositions and methods for enhancing enzyme activity, half-life and/or thermostability. Also provided herein are compositions and methods including the enhanced enzymes. Also provided herein are methods and compositions related to improved pectinolytic enzymes, such as pectate lyase, which exhibit enhanced activity, thermostability and/or longer half-life.
Council of Scientific & Industrial Research (India)
University of Calcutta (India)
Inventor
Bandyopadhyay, Uday
Pal, Chinmay
Bindu, Samik
Adhikari, Susanta Sekhar
Abstract
The synthesis and evaluation of gastroprotective effect of different tryptamine derivatives. Tryptamine derivatives have been synthesized by formation of amide or ester with some known anti oxidant molecules. These derivatives show excellent antioxidant property in vitro. Among all the derivatives the compound SEGA (3a), that was prepared by the combination of serotonin with gallic acid shows the greater antioxidant property than the other synthesized compounds both in vivo and in vitro. SEGA(3a) shows the gastroprotective effect against NSAIDs (indomethacin or diclofenac)-induced gastropathy in dose dependent manner and also accelerates the healing from injury. It prevents the NSAIDs-induced mitochondrial oxidative stress in vivo. This derivative prevents NSAID-induced mitochondrial oxidative stress-mediated apoptosis in vivo by preventing the activation of caspase 9 and caspase-3 and restores NSAIDs-mediated collapse of mitochondroial transmembrane potential and dehydrogenase activity. SEGA (3a) plays an important role as an iron chelator as well as intra mitochondrial ROS scavenger. Thus, SEGA (3a) is a potent antioxidant antiapototic molecule, which efficiently prevents NSAID-induced gastropathy and stress or alcohol-mediated gastric damage.
Technologies are generally described for providing and using a material including: a template molecule; a first cluster of one or more nanoparticles located at a first site on the template molecule; and a second cluster of one or more nanoparticles located at a second site on the template molecule and spaced apart from the first cluster. In some embodiments, the first and second clusters of nanoparticles exhibit a plasmon resonance having a first resonant peak and a second resonant peak.
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
Technologies are generally described for systems and methods for detecting chiral properties of materials and separating materials based on their chiral properties. A chiral vector is constructed from anisotropy properties of a polarization-dependent output signal from a sample. Different types of molecules from the sample can be differentiated based on a magnitude of the chiral vector. Chiral properties of the sample can be detected based on an angle of the chiral vector. The output signal can be a fluorescent emission from the sample and can be used to detect chiral properties of a substantially opaque sample.
A method includes detecting D20 in a sample by fluorescence spectroscopy. The fluorescence spectroscopy may be near-infrared fluorescence spectroscopy. The method may include observing an excitation wavelength of the sample at 620 nm to 640 nm. The method may also include observing an emission wavelength of the sample at 900 nm to 1000 nm. The method includes detecting D20 and D20 nano- clusters and their alterations in presence of suspended or colloidal objects including bio-molecules or cells, by emission spectroscopy.
G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
Techniques generally disclosed herein relate to computation of a guard zone of a three-dimensional object. In some examples, guard zones may be computed by identifying intersection lines that couple adjacent planes of an object, and categorizing an external angle at an intersection line between adjacent planes as concave or convex. In some embodiments, for convex angles, a cylindrical surface can be determined that is located about an outside surface of the object and centered along the intersection line between the adjacent planes. In some embodiments, for concave angles, the external angle can be bisected with a bisection plane. A guard zone may be formed by one or more of (i) providing a guard zone plane parallel to the object that is a tangent to a given cylindrical surface, (ii) providing a guard zone plane parallel to the object that intersects a given bisection plane, and/or (iii) coupling adjacent guard zone planes.
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (India)
UNIVERSITY OF CALCUTTA (--)
Inventor
Bandyopadhyay, Uday
Pal, Chinmay
Bindu, Samik
Adhikari, Susanta, Sekhar
Abstract
The present invention concerns the synthesis and evaluation of gastroprotective effect of different tryptamine derivatives. Tryptamine derivatives have been synthesized by formation of amide or ester with some known anti oxidant molecules. These derivatives show excellent antioxidant property in vitro. Among all the derivatives the compound SEGA (3 a), that was prepared by the combination of serotonin with gallic acid shows the greater antioxidant property than the other synthesized compounds both in vivo and in vitro. SEGA(3a) shows the gastroprotective effect against NSAIDs (indomethacin or diclofenac)-induced gastropathy in dose dependent manner and also accelerates the healing from injury. It prevents the NSAIDs-induced mitochondrial oxidative stress in vivo. This derivative prevents NSAID-induced mitochondrial oxidative stress-mediated apoptosis in vivo by preventing the activation of caspase 9 and caspase-3 and restores NSAIDs-mediated collapse of mitochondroial transmembrane potential and dehydrogenase activity. SEGA (3 a) plays an important role as an iron chelator as well as intra mitochondrial ROS scavenger. Thus, SEGA (3 a) is a potent antioxidant antiapototic molecule, which efficiently prevents NSAID-induced gastropathy and stress or alcohol -mediated gastric damage.
A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
21.
HYPER-LATTICE MODEL FOR OPTIMIZED SEQUENCING OF ONLINE ANALYTICAL PROCESSING (OLAP) OPERATIONS ON DATA WAREHOUSES
Systems and methods are provided for Online Analytical Processing of data included within data warehouses. According to one example, a method for adding a dimension to a hyper-lattice structure is provided and includes adding a new base cuboid to a hyper-lattice that describes functionality of the data warehouses. According to another example, a method for determining an optimal path through an existing hyper-lattice by which to generate a destination cuboid from a source cuboid is also provided.
The present technology provides processes for cross-linking cellulose ethers under mild conditions. The processes include exposing a substantially dry cellulose ether film to a polyisocyanate to provide a cross-linked cellulose ether film, wherein the substantially dry cellulose ether film comprises alkoxide groups on the cellulose. The resulting cellulose ether films are highly cross-linked by polyurethane linkages and may be used as membranes in a variety of applications.
Disclosed herein are methods of diagnosing, monitoring and treating iron disorders using assays of serum ferritin. Some embodiments relate to detection and management of iron and iron-containing proteins in the body. For instance, the level of ferritin may be determined by contacting a sample with one or more magnetic nanoparticles; measuring an absorbance of the sample in the presence and in the absence of a magnetic field; and comparing the absorbance of the sample in the presence of the magnetic field to the absorbance of the sample in the absence of the magnetic field to determine the level of ferritin in the sample.
G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
G01R 33/20 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance
Disclosed herein are compositions and methods for inhibiting platelet aggregation in a patient in need thereof. The compositions and methods use superparamagnetic iron oxide nanoparticles (SPIONs), which are shown to inhibit aggregation of platelets. Such methods are useful in preventing blood clotting in diseases such as acute coronary syndrome. Also disclosed are in vitro methods of sensing platelet function using SPIONs.
Disclosed are methods and systems for identifying and sorting cells based on a near-infrared emission pattern of the cell in response to excitation at 630 ± nm. The NIR emission pattern can be used for monitoring and sorting of cells in a label-free manner, and thus provides a positive method for selecting cells, such as stem cells, for use in therapy.
G01N 21/63 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
Disclosed are methods and apparatus for stabilizing labile biomolecules in an aqueous solution, the methods involvin the step of exposing an aqueous solution of a labile biomolecule, such as a protein, to light energy to stabilize the biomolecule in solution.
A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
A23C 3/07 - Preservation of milk or milk preparations by irradiation, e.g. by microwaves
A23L 3/26 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by irradiation without heating
A23B 5/015 - Preserving by irradiation or electric treatment without heating effect
A23L 3/005 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating using irradiation or electric treatment
A Link Layer (e.g., TCP/IP Layer 1, OSI Layer 2) routing protocol that routes frames from a sending node to a receiving node based upon service solicitation and availability is proposed. The routing protocol may reduce control messages across the layers, and may achieve greater energy efficiency by placing non-participating nodes into a sleep mode for durations of time while an ad hoc network is being utilized by participating nodes. The proposed scheme may also reduce network setup time by enabling routing as soon as a service and corresponding request is initiated.
Provided herein are non-human animal models and related methods useful for the identification, characterization, and analysis of the effects of environmental stimuli on the development and progression of pathological conditions. The environmental stimuli can include, but are not limited to, exposure to tobacco (e.g., cigarette, etc.) smoke. Exemplary pathological conditions include, but are not limited to, atherosclerosis, other cardiovascular disease (CVD), and the like. Also provided herein are non-human animal models and related methods useful for the identification, characterization, and analysis of pharmaceutical compounds, compositions, and/or formulations that can be used to prevent or treat a given pathological condition brought on by exposure to a given environmental condition.
The present invention discloses a process for detecting the presence or absence of human hemoglobin HbAO and/or HbE in a sample by way of nanoparticle - hemoglobin interaction. Clusters of copper nanoparticles (average cluster size 160nm) undergo a multi step transition on interaction with HbAO, the normal fraction of human hemoglobin. Longer interaction of HbAO with Cu nanoparticles leads to aggregation with the formation of micron sized structure, which immediately precipitates out of the solution. This nanoparticle and protein interaction helps to separate out specific proteins even if they have very close homology (like the discrimination of HbAO from HbC or HbE from Hb A2). The present invention has important applications in hemoglobinopathy in particular and proteomic applications in general.
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