Abstract

An optical fiber may include a cladding structure extending along a fiber length providing a hollow interior fiber region, and anti-resonant (AR) elements formed as walled structures with walls extending along the fiber length. At least one of the AR elements surrounds an interior region and further includes one or more support structures in the interior region and formed as at least a portion of at least one of the walls, where the one or more support structures have a non-uniform thickness profile, and where the plurality AR elements is configured to guide light along the fiber length in a central portion of the hollow interior fiber region based on optical anti-resonance.

IPC Classes  ?

• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding
• G02B 6/036 - Optical fibres with cladding core or cladding comprising multiple layers

Abstract

Multifunctional cerium oxide-P7C3 (aminopropyl carbazole) chimeric nanocompositions and methods for using these nanocompositions for enhancing bone deposition are provided. For example, these nanocompositions can be used to combat radiation-induced bone tissue/cell damage, to treat any disorders that promote osteoporosis, and/or to treat bone trauma/injury.

IPC Classes  ?

• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61K 47/55 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
• A61P 19/10 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

A glass fiber-based structural composite offers an alternative or supplement to carbon fibers in areas such as battery storage. Through electroless deposition of conductive materials like copper and nickel, the glass fiber surface is made conducting and functions as a good current collector. By using anode and cathode materials like manganese (II, III) oxide and Zinc, cathode and anode mats on the copper- and nickel-coated glass fibers are created via hydrothermal and electro-deposition methods. In one example application, the anode and cathode mats are in an alternate square patterned arrangement using copper and nickel-coated glass fiber as a current collector. The device, with a capacity of >300 mAh/g at 0.1 A/g is assembled using an alternate system of epoxy and electrolyte. Uncoated pristine glass fiber ladened and patterned with electrolyte are used as a separator. Uncoated pristine glass fiber ladened with epoxy can be used as an insulator between two devices.

IPC Classes  ?

• B60L 50/64 - Constructional details of batteries specially adapted for electric vehicles
• B60L 50/40 - Electric propulsion with power supplied within the vehicle using propulsion power supplied by capacitors
• B62D 29/04 - Superstructures characterised by material thereof predominantly of synthetic material
• H01G 11/04 - Hybrid capacitors
• H01G 11/10 - Multiple hybrid or EDL capacitors, e.g. arrays or modules
• H01G 11/26 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features
• H01G 11/52 - Separators
• H01G 11/62 - Liquid electrolytes characterised by the solute, e.g. salts, anions or cations therein
• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/058 - Construction or manufacture
• H01M 50/437 - Glass
• H01M 50/44 - Fibrous material
• H01M 50/457 - Separators, membranes or diaphragms characterised by the material having a layered structure comprising three or more layers

Abstract

Described herein relates to a system and method of water treatment that integrates green sorption media with nanofiltration for the effective removal of perfluoroalkyl substances and/or polyfluoroalkyl substances (PFAS) from contaminated fluid. As such, the water filtration system may include a filtration chamber configured to pretreat the fluid prior to membrane filtration via the green sorption media. The green sorption media may comprise natural and/or recycled materials, including but not limited to sand, clay, perlite, and/or optionally zero-valent iron (ZVI), which pre-treats the fluid by adsorbing the perfluoroalkyl substances and/or polyfluoroalkyl substances. Additionally, the water treatment system may further comprise a crossflow nanofiltration chamber having at least one nanofiltration membrane configured to remove additional PFAS through size exclusion and/or electrostatic repulsion. The combined approach within the water treatment system may enhance the overall removal efficiency, particularly for the PFAS, while also reducing membrane fouling and/or extending operational life.

IPC Classes  ?

• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 101/14 - Fluorine or fluorine-containing compounds

Abstract

A method of domain knowledge learning by developing a language model from medical data. One application of the invention includes the steps of receiving a medical examination dataset, executing a data processing procedure, and providing an automatic short answer grading mechanism. The method also includes determining a final decision of the grade by aggregating the deciding factors in the final grade and reporting the results' uncertainty.

IPC Classes  ?

• G06N 3/094 - Adversarial learning
• G06F 40/295 - Named entity recognition
• G16H 70/00 - ICT specially adapted for the handling or processing of medical references

Abstract

An implant is provided comprising a substrate having one or more nanoceria coatings coated at least partially thereon, wherein the one or more nanoceria coatings comprise surface cerium having a 3+/4+ oxidation state ratio such that the one or more nanoceria coatings exhibit catalase mimetic activity, superoxide dismutase mimetic activity, or both. Methods are provided for forming a nanoceria coating. The coating has nanoceria having a surface cerium 3+/4+ oxidation state ratio such that such that the coating exhibits catalase mimetic activity, superoxide dismutase mimetic activity, or both. Also disclosed is a method of reducing degradation of an implant by placing nanoceria in proximity to a bone-implant interface.

IPC Classes  ?

• A61L 27/30 - Inorganic materials
• A61L 27/04 - Metals or alloys
• A61L 27/10 - Ceramics or glasses
• A61L 27/14 - Macromolecular materials
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• C25D 13/02 - Electrophoretic coating characterised by the process with inorganic material
• C25D 13/12 - Electrophoretic coating characterised by the process characterised by the article coated
• C25D 13/18 - Electrophoretic coating characterised by the process using modulated, pulsed or reversing current
• C25D 15/00 - Electrolytic or electrophoretic production of coatings containing embedded materials, e.g. particles, whiskers, wires

Abstract

The compositions, methods, and systems described herein are useful in treating subjects suffering from or at risk of developing Intrauterine Growth Restriction.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
• A61K 31/712 - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
• A61K 31/7125 - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
• A61K 33/244 - LanthanidesCompounds thereof
• A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61K 9/50 - Microcapsules
• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances

Abstract

Efficient lung cancer treatment is challenging due to the lack of therapeutic targets. The succinate dehydrogenase (SDH) enzyme plays a critical metabolic role as an intermediate between the citric acid cycle and the electron transport chain associated with the cancer disease state. Although several existing compounds have been applied to target metabolic diseases in vitro, modulating SDH for lung cancer treatment has been elusive. By integrating the AtomNet® technology for compound identification with mitochondria- and cell-based enzyme activity assays, this disclosure demonstrates identification of four new small molecules that bind directly to SDH subunits in lung cancer cells. Mechanistically, treatment with these small molecules increased reactive oxygen species and DNA damage in lung cancer cell lines. Functionally, these small molecules reduced short-term and long-term malignant growth of lung cancer cell lines in vitro. This study provides a new therapeutic approach for targeting lung and other types of cancers through modulation of SDH.

IPC Classes  ?

• A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
• A61K 31/44 - Non-condensed pyridinesHydrogenated derivatives thereof
• A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
• A61K 31/33 - Heterocyclic compounds

Abstract

A method of skin anomaly assessment, measurement, and monitoring is disclosed. The three-dimensional topology of a skin anomaly is digitally scanned, and a three-dimensional model of the skin anomaly is computationally constructed. From the three-dimensional model, length, width, depth, perimeter, and surface area measurements of the skin anomaly are derived. This information may be quantified by volume surface area, and/or distance along the surface of the anomaly, and measured against models of anticipated healing for medical monitoring and training.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
• G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring

Abstract

Disclosed herein are novel compositions and methods for stimulation of and the production or expansion of natural killer (NK) cells. Numbers of NK cells can be increased following contact with exosomes modified with one or more stimulatory peptides. Methods and compositions for the production of exosomes, wherein the exosomes comprises stimulatory peptides are also described. Also described are methods of treating cancer using the disclosed NK-stimulating exosomes or NK cells stimulated by the disclosed methods.

IPC Classes  ?

• A61K 35/13 - Tumour cells, irrespective of tissue of origin
• A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61K 38/20 - Interleukins
• C07K 14/54 - Interleukins [IL]
• C07K 14/55 - IL-2
• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells

Abstract

A power semiconductor waveguide optical amplifier (P-SWA) may include an amplifier waveguide with an invertible core formed from one or more undoped heterogeneous semiconductor layers and one or more cladding layers surrounding one or more sides of the invertible core formed as one or more undoped semiconductor layers. Pump light may be coupled into the amplifier waveguide to induce the population inversion in the invertible core. Signal light may further be coupled into the amplifier waveguide and may be amplified as it propagates through the amplifier waveguide. The signal light may then exit the amplifier waveguide as amplified signal light.

IPC Classes  ?

• H01S 3/067 - Fibre lasers
• H01S 3/094 - Processes or apparatus for excitation, e.g. pumping using optical pumping by coherent light
• H01S 3/16 - Solid materials
• H01S 5/026 - Monolithically integrated components, e.g. waveguides, monitoring photo-detectors or drivers
• H01S 5/04 - Processes or apparatus for excitation, e.g. pumping
• H01S 5/10 - Construction or shape of the optical resonator

Abstract

Described herein relates to a low-cost, synergistic, and/or green sorption media and methods thereof capable of removing MC-LR in-situ over different landscapes. The synergistic composition may include a mixture of a plurality of sand particles, a plurality of biochar particles, a plurality of clay particles, a plurality of zero-valent iron (hereinafter “ZVI”) iron molecules, and/or a plurality of perlite particles. In certain embodiments, the plurality of clay particles, plurality of ZVI molecules, and/or plurality of perlite particles may have an approximately equal volume percentage, with the volume percentage being less than or equal to a volume percentage of the plurality of biochar particles. Furthermore, the synergistic composition may be homogenously mixed and/or included in a media chamber of a filtration system.

IPC Classes  ?

• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• C02F 101/38 - Organic compounds containing nitrogen

Abstract

An active sparse labeling system that provides high performance and low annotation costs by performing partial instance annotation (i.e., sparse labeling) by frame level selection to annotate the most informative frames, thereby improving action detection task efficiencies. The active sparse labeling system utilizes a frame level cost estimation to determine the utility of each frame in a video based on the frame's impact on action detection. The system includes an adaptive proximity-aware uncertainty model, which is an uncertainty-based frame scoring mechanism. The adaptive proximity-aware uncertainty model estimates a frame's utility using the uncertainty of detections of the frame's proximity to existing annotations, thereby determining a diverse set of frames in a video which are effective for learning the task of dense video understanding (such as action detection). In addition, the active sparse labeling system includes a loss formulation training model (max-Gaussian weighted loss) that uses weighted pseudo-labeling.

IPC Classes  ?

• G06V 20/70 - Labelling scene content, e.g. deriving syntactic or semantic representations
• G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting

Abstract

The systems disclosed herein can include a cell culture surface having a silicon oxide first layer and second layer comprising a plurality of amphiphilic molecules, each amphiphilic molecule having a positively charged portion extending from a silane portion that is bound to the silicon oxide first layer. The cell culture surface can also include extracellular matrix components and water molecules dispersed between and bonded to positively charged portions of the amphiphilic molecules. Methods of using the systems can include plating mechanically active cells onto the cell culture surface, forming a mechanically active cell culture, and maintaining the mechanically active cell culture in a mechanically active state and adhered to the cell culture surface for at least 14 days. The mechanically active cell culture can be exposed to an agent and responses of the mechanically active cell culture to the agent can be detected.

IPC Classes  ?

• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The present invention relates to an advanced augmented reality, AR, apparatus featuring a video see-through AR, VST-AR, device that captures images of a real-world environment and displays augmented versions on a screen. The system includes a corporal entity, such as an empty laboratory vessel, equipped with a unique identification marker. This marker provides real-time spatial data for generating visual augmentations representing virtual matter within the vessel. The apparatus integrates various sensors, including an inertial measurement unit, IMU, capacitive tactile sensors, and a thermal diode, to dynamically adjust visual augmentations based on user interactions. Additional sensory enhancements include an olfactory output fan, an eccentric rotating mass, ERM, motor, and auditory outputs. Wireless connectivity via IEEE 802.11 (Wi-Fi) and IEEE 802.15.1 (Bluetooth) ensures seamless communication between components. This AR system is particularly valuable for educational and laboratory settings, offering realistic, interactive simulations.

IPC Classes  ?

• G06V 20/20 - ScenesScene-specific elements in augmented reality scenes
• G09B 19/24 - Use of tools
• G02B 27/01 - Head-up displays
• H04N 13/106 - Processing image signals
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G06F 18/24 - Classification techniques
• G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
• G09B 23/24 - Models for scientific, medical, or mathematical purposes, e.g. full-sized device for demonstration purposes for chemistry
• G09B 5/02 - Electrically-operated educational appliances with visual presentation of the material to be studied, e.g. using film strip

Abstract

A real-time position location system can include one or more location modules configured to be attached to a user or a weapon of the user and to output location data associated with each user and one or more kinematic base station modules configured to receive the location data from each location module. The system can include a position module operatively connected to the one or more kinematic base stations and configured to determine a real-time location of each of the one or more location modules and to output module position data for each of the one or more location modules in real-time.

IPC Classes  ?

• F41G 3/26 - Teaching or practice apparatus for gun-aiming or gun-laying
• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer

Abstract

An optical fiber may include a cladding structure extending along a fiber length providing a hollow interior fiber region, and anti-resonant (AR) elements formed as walled structures with walls extending along the fiber length. At least one of the AR elements surrounds an interior region and further includes one or more support structures in the interior region and formed as at least a portion of at least one of the walls, where the one or more support structures have a non-uniform thickness profile, and where the plurality AR elements is configured to guide light along the fiber length in a central portion of the hollow interior fiber region based on optical anti-resonance.

IPC Classes  ?

• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding
• G02B 6/036 - Optical fibres with cladding core or cladding comprising multiple layers

Abstract

A monolithically 3D printed array of microchannels in a multilayer circuit includes a base substrate and integrated microchamber to form a microelectrode array (MEA) device. Microchannels at different levels serve as conduits towards a centrally located 2.5D/3D Microelectrode Array (MEA) for electrical stimulation/recording of electrogenic spheroids, and as inlet/outlet for injection/suction of liquids, e.g., samples or reagents. The microchamber allows for control and isolation of the cultured microenvironment, and additionally perfusion of gases, such as O2 and CO2 for electroactive responses. The device is operative with organoids under Phosphate Buffer Saline (PBS) and sample gas (Oxygen) injection.

IPC Classes  ?

• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
• G01N 33/487 - Physical analysis of biological material of liquid biological material

Abstract

An optical fiber may include a cladding structure extending along a fiber length providing a hollow interior fiber region and anti-resonant (AR) elements distributed within the interior fiber region. Each of the AR elements may be formed as walled structures with walls extending along the fiber length, where at least some of the plurality of AR elements are nested to form one or more nested sets of AR elements. At least one of the nested sets of AR element may include a first AR element of the plurality of AR elements, where an interior region of the first AR element is segmented into two or more interior cavities by one or more segmentation walls extending along the fiber length. At least one of the two or more interior cavities of the first AR element may include two or more second AR elements of the plurality of AR elements.

IPC Classes  ?

• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding

Abstract

Techniques for stochastic control of at least one load is provided. Electric power generators provide alternating current (AC) to a plurality of consumer premises (CP). Each CP has one or more loads configured to be electrically powered by the AC. The stochastic control is performed at each consumer premises in a distributed manner. The stochastic control is used to maintain or increase the frequency of the AC provided by an AC electrical power distribution grid when such AC frequency falls below a nominal AC frequency of the AC electrical power distribution grid.

IPC Classes  ?

• G06N 7/01 - Probabilistic graphical models, e.g. probabilistic networks
• G06F 7/58 - Random or pseudo-random number generators

Abstract

Disclosed is a method to amplified nucleic acids by polymerase chain reaction (PCR) without isolation or purification from the biological samples. All the reactions associated with reverse transcriptase qPCR or real-time qPCR are completed on a filter paper chamber using a handheld Real-time PCR device. The process requires a very small amount of sample since there is no loss of materials associated with isolation and purification steps. The amplification process is faster than a normal tube-based PCR reaction because the thin chamber makes heating and cooling process fast. This technique is applicable in the rapid detection of pathogenic viruses from body fluids, such as COVID-19 detection in saliva. The technology is valuable for quantitative detection of nucleic acids that are established markers of diseases. Novel use of a piece of filter paper to perform sample collection, storage, and conduct direct PCR amplification without any extraction of the sample will allow us to test infections and the diseases anywhere by anybody without the requirement of technical knowledge or skills.

IPC Classes  ?

• B01L 7/00 - Heating or cooling apparatusHeat insulating devices
• C12Q 1/6844 - Nucleic acid amplification reactions

Abstract

An optical fiber may include a cladding structure extending along a fiber length providing a hollow interior fiber region and anti-resonant (AR) elements distributed within the interior fiber region. Each of the AR elements may be formed as walled structures with walls extending along the fiber length, where at least some of the plurality of AR elements are nested to form one or more nested sets of AR elements. At least one of the nested sets of AR element may include a first AR element of the plurality of AR elements, where an interior region of the first AR element is segmented into two or more interior cavities by one or more segmentation walls extending along the fiber length. At least one of the two or more interior cavities of the first AR element may include two or more second AR elements of the plurality of AR elements.

IPC Classes  ?

• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding

Abstract

An imaging element may include volume Bragg grating (VBG) within a material, where the material has an input face, and where the VBG is formed as a periodic distribution of curved surfaces of refractive index variation with chirped periodicity in a volume of the material. The periodic distribution of curved surfaces of refractive index variation forming the VBG may be selected to image different object planes oriented parallel to the input face onto different lateral locations of a single image plane with different wavelengths via the Bragg diffraction.

IPC Classes  ?

• G02B 5/18 - Diffracting gratings
• G02B 5/32 - Holograms used as optical elements
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details

Abstract

An optical display system and an electronic device are disclosed. The optical display system comprises: a controllable optical image-generating display apparatus, generating circularly polarized image output; a beam scanning unit, adjusting a direction of the circularly polarized image output; an exit pupil steering apparatus, including diffractive liquid crystal lenses, each of which focuses the circularly polarized image output of one circular polarization state to a distinct focus point and let light with the other circular polarization state pass directly through; and an eye-tracking apparatus, detecting position information of a viewer's eye pupil and providing the position information to the beam scanning unit. The beam scanning unit adjusts the direction of the circularly polarized image output according to the position information, so that the circularly polarized image output is diffracted by one of the diffractive liquid crystal lenses.

IPC Classes  ?

• G02B 27/01 - Head-up displays
• G02B 3/12 - Fluid-filled or evacuated lenses
• G02B 5/18 - Diffracting gratings
• G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
• G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising

Abstract

Described herein relates to methods of accurately determining DNA barcodes using a cylindrical nanopore system. The system and method may include the steps of leveraging the average velocity of a double-stranded DNA segment passing through a single cylindrical nanopore that may be measured through repeated scanning to accurately determine protein tag locations on the double-stranded DNA segment. As such, the system and methods may provide for the accurate calculation of a barcode for the double-stranded DNA segment based on protein tag locations without underestimation or overestimate issues. Additionally, the underlying concept and/or the system and/or the methods may be equally applicable to other multi-nanopore systems which use the dwell time and/or time of flight velocities to measure the barcodes.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• G06F 17/18 - Complex mathematical operations for evaluating statistical data

Abstract

Described herein relates to an optimum, low maintenance and low-cost filtration media which may be implemented near a source water location as a pretreatment to remove tannic acid and/or humic acid (color) from dissolved natural organic matter (NOM) (i.e., tannic acid, humic acid) to impede the prompt production of disinfection by-products collectively termed trihalomethanes in drinking water treatment processes. In an embodiment, the filtration media may comprise a composition having a ratio of at least 83% sand, at most 5% clay, at most 6% ZVI and at most 6% perlite by percent volume.

IPC Classes  ?

• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• B01J 20/04 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
• B01J 20/10 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
• B01J 20/12 - Naturally occurring clays or bleaching earth
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• C02F 101/10 - Inorganic compounds
• C02F 101/30 - Organic compounds
• C02F 101/34 - Organic compounds containing oxygen
• C02F 103/00 - Nature of the water, waste water, sewage or sludge to be treated
• C02F 103/06 - Contaminated groundwater or leachate

Abstract

An optical fiber may include a cladding structure extending along a fiber length providing a hollow interior fiber region, and anti-resonant (AR) elements formed as walled structures with walls extending along the fiber length. At least one of the AR elements surrounds an interior region and further includes one or more support structures in the interior region and formed as at least a portion of at least one of the walls, where the one or more support structures have a non-uniform thickness profile, and where the plurality AR elements is configured to guide light along the fiber length in a central portion of the hollow interior fiber region based on optical anti-resonance.

IPC Classes  ?

• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding
• C03B 37/027 - Fibres composed of different sorts of glass, e.g. fibre optics
• G02B 6/024 - Optical fibres with cladding with polarisation-maintaining properties
• G02B 6/036 - Optical fibres with cladding core or cladding comprising multiple layers

Abstract

A method is for forming a radiation shield around an object. The method includes providing an inorganic paint pigment comprising a fluid matrix, and paint flakes carried within the fluid matrix. Each paint flake includes a common aluminum mirror layer having a first major surface and a second major surface opposing the first major surface, a first plasmonic aluminum reflector layer carried by the first major surface, and a second plasmonic aluminum reflector layer carried by the second major surface. The method also includes coating an outer surface of the object with the inorganic paint pigment.

IPC Classes  ?

• C09D 5/32 - Radiation-absorbing paints
• C09D 7/62 - Additives non-macromolecular inorganic modified by treatment with other compounds
• C09D 7/40 - Additives
• C09D 7/20 - Diluents or solvents
• C09C 1/00 - Treatment of specific inorganic materials other than fibrous fillers Preparation of carbon black
• C08K 9/02 - Ingredients treated with inorganic substances

Abstract

A system and method for wavefront correction is achieved using an adaptive optics photonic integrated circuit with monitoring per stage. The method begins with receiving a single optical data signal contained in a distorted wavefront, wherein a single optical signal is divided into a plurality of parts, each representing a unique propagation path through free space, wherein the plurality of parts of the single optical signal is received by a programmable optical processor consisting of cascaded Mach-Zehnder Interferometers (MZi) each with a first phase shifter and a second phase shifter. Next, the settings are adjusted of each of the first phase shifter and the second phase shifter until the plurality of parts of the single optical signal are combined into one output of a last MZi, wherein the settings of the first phase shifter and the setting of the second phase shifter of each MZi are controlled by independent measurements.

IPC Classes  ?

• H04B 10/112 - Line-of-sight transmission over an extended range
• H04B 10/079 - Arrangements for monitoring or testing transmission systemsArrangements for fault measurement of transmission systems using an in-service signal using measurements of the data signal
• H04B 10/61 - Coherent receivers

Abstract

Described herein relates to apparatus and method for developing a free-standing zwitterion-promoted hybrid clay film having excellent ionic conductivity, thermal stability, and/or chemical stability. As such, in an embodiment the clay film apparatus may comprise biocompatible materials, including but not limited to clay and trimethyl glycine (hereinafter “TMG”), also known as a zwitterion. Additionally, in an embodiment, the clay film apparatus may be synthesized utilizing a simple method for making a free-standing flexible, non-polymeric clay film. Moreover, in an embodiment, the prepared film's increased porosity, superior thermal and chemical stability, electrically insulating, and ionic conductivity, as compared to clay films known in the art, may make it an excellent material for energy applications as an ion-conducting membrane. The applications may include but are not limited to battery separators, electrolyte membranes in fuel cells, and solid electrolyte membranes in batteries.

IPC Classes  ?

• B01D 71/02 - Inorganic material
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 69/12 - Composite membranesUltra-thin membranes

Abstract

Various embodiments relate to a microserpentine including a plurality of u-bends, each having a degree of completeness (α), in which an α value of 0° corresponds to a semi-circular shape, and in which an α value of +90° corresponds to a complete circle and −90° corresponds to a straight shape. Each of the plurality of u-bends may have an α value of from about −35° to about 45°. The microserpentine may include a core coated with a conductive coating. The core may include a polymeric material. Various embodiments relate to microelectronic devices and methods of producing the same. The microelectronic devices may include but are not limited to a microelectrode array, a microelectronics packaging, an interconnect, a stretchable sensor, a wearable sensor, a wearable actuator, an in vitro sensor, an in vivo sensor, and combinations thereof.

IPC Classes  ?

• H01B 7/06 - Extensible conductors or cables, e.g. self-coiling cords
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• H05K 1/02 - Printed circuits Details

Abstract

Compositions, methods, and kits relating to substantially monodisperse, ultrasound targeted nanobubble compositions are disclosed. The nanobubble compositions comprise a hollow core containing at least one gas and a polymer shell encircling the hollow core. Methods of producing the substantially monodisperse nanobubble compositions using an ultrasound shearing-based fabrication method are disclosed. Methods of using the nanobubble compositions are also disclosed.

IPC Classes  ?

• A61K 49/22 - Echographic preparationsUltrasound imaging preparations
• A61K 51/12 - Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
• A61K 31/02 - Halogenated hydrocarbons
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation

Abstract

A method to coat active pharmaceutical ingredient (API) powders with atomically thin layers of biocompatible metal oxide films such as aluminum oxide and zinc oxide films. Metal oxide films provide a barrier that controllably dissolves and releases the active pharmaceutical ingredients (APIs) in different pH environments such as is found in the human gastrointestinal (GI) tract. Coated API powders, can be prepared using the described methods, such as 5-Aminosalicylic acid (5-ASA) powder coated with aluminum oxide and zinc oxide films.

IPC Classes  ?

• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid

Abstract

Numerous fields of basic research, medicine, and technology require an understanding of the biological composition and diversity in water samples. A common approach to acquiring such information is to collect samples ‘in the field’ and to subsequently extract nucleic acids in a laboratory for sequence analyses. A challenge to this pipeline is the preservation of the abundance and quality of the nucleic acids present in and around the organisms because, once a sample is harvested, it is no longer connected to the environment that established it. Many organisms, particularly microbes, rapidly adapt to such environmental changes and the relative abundance and quality of nucleic acids within them can change in a manner of minutes. A common methodology intended to address this problem is to filter the water to collect microorganisms on site and then to store the filters in a frozen state until they are processed. This technique creates several problems: the filter systems are expensive, require a vacuum, and are cumbersome to operate; the microbes change their metabolisms as they are filtered; freezing the samples requires substantial infrastructure at the collection site and during transport; and freezing and thawing many organisms causes their cells to break open, which releases their nucleic acids. The disclosed invention circumvents these problems by allowing microorganisms and their nucleic acids to be rapidly preserved on site using simple collection vessels, without the need for refrigeration or freezing. The methodology allows for the subsequent recovery and processing of nucleic acids for downstream molecular analyses. Although the current embodiment was developed for sea water collection, it can be also be applied to other aqueous samples

IPC Classes  ?

• A01N 1/02 - Preservation of living parts

Abstract

A patient simulation system for healthcare training is provided. The system includes one or more interchangeable shells comprising a physical anatomical model of at least a portion of a patient's body, the shell adapted to be illuminated from within the shell to provide one or more dynamic images viewable on the outer surface of the shells; wherein the system comprises one or more imaging devices enclosed within the shell and adapted to render the one or more dynamic images on an inner surface of the shell and viewable on the outer surface of the shells; one or more interface devices located about the patient shells to receive input and provide output; and one or more computing units in communication with the image units and interface devices, the computing units adapted to provide an interactive simulation for healthcare training. In other embodiments, the shell is adapted to be illuminated from outside the shell.

IPC Classes  ?

• G09B 23/34 - Anatomical models with removable parts
• A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
• G09B 23/28 - Models for scientific, medical, or mathematical purposes, e.g. full-sized device for demonstration purposes for medicine
• G09B 23/30 - Anatomical models
• G09B 23/32 - Anatomical models with moving parts
• H04N 9/31 - Projection devices for colour picture display
• H04N 23/698 - Control of cameras or camera modules for achieving an enlarged field of view, e.g. panoramic image capture

Abstract

This invention relates to a self-supervised privacy preservation action recognition system leveraging a learnable transformation anonymization function. The system is designed to process videos by removing spatial cues to protect privacy while retaining critical information for action recognition. The anonymization function, based on an encoder-decoder model, undergoes iterative training on a dataset to optimize the balance between obscuring privacy-sensitive information and preserving capability of recognizing actions. This training involves freezing and adjusting the weights of an action recognition branch and a self-supervised privacy removal branch to refine the model's effectiveness. The outcome is an anonymized video with minimized privacy information leakage, suitable for action analysis without privacy labels. Additional functionalities include frame sampling for enhanced privacy evaluation, data augmentation for model robustness, and a minimax optimization protocol ensuring optimal action recognition accuracy alongside privacy preservation.

IPC Classes  ?

• G06V 20/52 - Surveillance or monitoring of activities, e.g. for recognising suspicious objects
• G06F 21/62 - Protecting access to data via a platform, e.g. using keys or access control rules
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
• G06V 20/40 - ScenesScene-specific elements in video content
• G06V 40/20 - Movements or behaviour, e.g. gesture recognition

Abstract

Described herein relates to system and method for detecting an abnormal presence within at least one dataset. In an embodiment, the dataset may comprise 1D signals, and/or multidimensional signals (e.g., images). The multi-field data analysis system (hereinafter “system”) may be configured to detect at least one type of abnormality that may not be detected visually otherwise (e.g., analysis by an expert). In addition, the system may be configured to detect the size and/or shape of the abnormality. In this embodiment, the system may also retain the physical location (spatial information) of the abnormality. As such, the system may optimize computation and/or implementation due to the system's ability to project the data on any appropriate domain (e.g., transform domains). Moreover, the system may be configured to search for abnormalities and/or particular characteristics any biometric signal known in the art.

IPC Classes  ?

• G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]
• G06T 7/00 - Image analysis
• G06T 7/11 - Region-based segmentation

Abstract

A system for use in determining parking spot allocation. The system includes a host vehicle parked in a host parking spot. The host vehicle includes a transceiver configured for vehicle-to-vehicle communication, and a control unit configured to determine the host vehicle is ready to depart the host parking spot, receive, via the transceiver, a first signal from at least one client vehicle, wherein the first signal indicates the at least one client vehicle is searching for a parking spot, allocate the host parking spot to a first client vehicle of the at least one client vehicle; and transmit, via the transceiver, a second signal to the first client vehicle, wherein the second signal notifies the first client vehicle that the host parking spot has been allocated to the first client vehicle, and provides location data associated with the host parking spot to the first client vehicle.

IPC Classes  ?

• G08G 1/14 - Traffic control systems for road vehicles indicating individual free spaces in parking areas
• H04W 4/44 - Services specially adapted for particular environments, situations or purposes for vehicles, e.g. vehicle-to-pedestrians [V2P] for communication between vehicles and infrastructures, e.g. vehicle-to-cloud [V2C] or vehicle-to-home [V2H]

Abstract

An optical receiver may include multiple photodetectors connected in serial and an amplifier connected to the photodetectors, where the amplifier is configured to amplify an electrical signal generated by the photodetectors in response to illumination. The receiver may further include one or more optical elements to receive signal light and direct the signal light to a subset of the plurality of photodetectors. The receiver may further include an illumination source to illuminate the plurality of photodetectors with flood illumination during operation. An optical modulator may include multiple modulators connected in serial and driven by a common voltage driver.

IPC Classes  ?

• G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors
• G01J 1/44 - Electric circuits
• G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
• G02F 1/015 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on semiconductor elements having potential barriers, e.g. having a PN or PIN junction

Abstract

Provided herein is a system for use in determining right-of-way. The system includes a host vehicle at or approaching an intersection, and the host vehicle includes a transceiver configured for vehicle-to-vehicle communication and a control unit. The control unit is configured to receive a local map of an area surrounding the intersection; receive, via the transceiver, a first signal from at least one client vehicle, wherein the first signal indicates the at least one client vehicle is at or approaching the intersection; determine, based upon a set of rules, that the host vehicle is an arbitrator, wherein the arbitrator assigns a priority value for right-of-way to each vehicle at or approaching the intersection; and transmit, via the transceiver, a second signal to the at least one client vehicle, wherein the second signal includes the assigned priority values for each vehicle at or approaching the intersection.

IPC Classes  ?

• G08G 1/16 - Anti-collision systems
• H04W 4/46 - Services specially adapted for particular environments, situations or purposes for vehicles, e.g. vehicle-to-pedestrians [V2P] for vehicle-to-vehicle communication [V2V]

Abstract

A nickel-free and cobalt-free cathode for a lithium (Li) battery is provided. The lithium manganese composite oxide material of the cathode has a sloping discharge voltage profile between 3V to 4 V. The material comprises multiple crystal structures with R3-m, C2/m, and Pmnm space groups, and is characterized to maintain a high capacity when these phases are in a specific ratio.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy

Abstract

Anti-malarial compounds are disclosed for administration to subjects infected or at risk of being infected with a Plasmodium sp.

IPC Classes  ?

• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 33/06 - Antimalarials

Abstract

A light source may include an array of grating-coupled semiconductor optical amplifiers (GC-SOAs) arranged along a surface of a substrate, where the array of GC-SOAs receive seed light from a common seed source, and where the array of GC-SOAs provide an array of SOA output beams associated with amplification of the seed light at a non-zero angle from the surface of the substrate. A light source may further include one or more phase shifters configured to provide that the SOA output beams are phase-locked.

IPC Classes  ?

• H01S 5/40 - Arrangement of two or more semiconductor lasers, not provided for in groups
• H01S 5/04 - Processes or apparatus for excitation, e.g. pumping
• H01S 5/068 - Stabilisation of laser output parameters
• H01S 5/0683 - Stabilisation of laser output parameters by monitoring the optical output parameters

Abstract

A multiplication unit, such as a photonic multiplication unit, for multiplication of a floating point number is claimed. A first signal is produced representing an exponent of a floating point number mapped onto a frequency of a harmonic wave. A second signal is produced representing a significant of the floating point number mapped onto an amplitude of the harmonic wave to produce a floating point number. There are numerous examples of how the floating point number may be used, such as displayed, stored in a fixed, non-transitory, storage medium for later retrieval, used in a mathematical operation using cascade modulation, used in a mathematical operation using interference, used in a mathematical operation using interference with a comb filter, used in a mathematical operation using cascade operation with summation. The multiplication unit includes is extendable to a multiplication unit for vector, matrix or tensor multiplication using interference or o beam combiner.

IPC Classes  ?

• G06F 7/487 - MultiplyingDividing

Abstract

A system and method for evaluating Boolean functions using in-memory computing comprising a plurality of programmed non-volatile memory devices synthesized in a crossbar design. The evaluation phase of a given Boolean function using the programmed non-volatile memory devices is accomplished using READ operations only.

IPC Classes  ?

• G06F 3/06 - Digital input from, or digital output to, record carriers

Abstract

The system extracts water from lunar regolith and includes a regolith intake having a digging bucket that collects lunar regolith soil and a gravel separator that separates and discharges gravel and passes a mixture of ice-regolith powder having ice grains that are about 10-100 microns along the conveyor. A pneumatic separator receives the ice-regolith powder and pneumatically splits the ice-regolith powder into streams of different sized lithic fragments and ice particles per the ratio of inertial force and aerodynamic drag force of the lithic fragments and ice particles. Each split stream may include a magnetic separator that separates further the magnetic and paramagnetic lithic fragments from ice particles to discharge up to 80 percent of lithic fragments to slag.

IPC Classes  ?

• E21C 51/00 - Apparatus for, or methods of, winning materials from extraterrestrial sources
• B03C 1/30 - Combinations with other devices, not otherwise provided for
• B03C 7/02 - Separators
• B04C 9/00 - Combinations with other devices, e.g. fans
• B64G 4/00 - Tools specially adapted for use in space
• B64G 5/00 - Ground equipment for vehicles, e.g. starting towers, fuelling arrangements

Abstract

CNN-based methods for cross-view image geo-localization rely on polar transform and fail to model global correlation. A pure transformer-based approach (TransGeo) is described to address these limitations from a different perspective. TransGeo takes full advantage of the strengths of the transformer related to global information modeling and explicit position information encoding. The claimed invention further leverages transformer input's flexibility and discloses an attention-guided non-uniform cropping method so that uninformative image patches are removed with a negligible drop in performance to reduce computation cost. The saved computation can be reallocated to increase resolution only for informative patches, resulting in performance improvement with no additional computation cost. This “attend and zoom-in” strategy is highly similar to human behavior when observing images. Remarkably, TransGeo achieves state-of-the-art results on both urban and rural datasets, with significantly less computation cost than CNN-based methods. It does not rely on polar transform and provides faster methods.

IPC Classes  ?

• G06T 3/4053 - Scaling of whole images or parts thereof, e.g. expanding or contracting based on super-resolution, i.e. the output image resolution being higher than the sensor resolution
• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects

Abstract

Here discloses a method for duplicating a hologram and a hologram optical element. The method comprises: preparing a master with a master hologram; preparing a sample with coated photoalignment material layer above the master; and irradiating a recording light through the sample to the master, so that at least one portion of the recording light is reflected by the master as an object light carrying the master hologram information, and so that the object light and the recording light are interfered at the photoalignment material layer to produce a duplicated hologram in the photoalignment material layer.

IPC Classes  ?

• G03H 1/20 - Copying holograms by holographic means
• G02B 5/32 - Holograms used as optical elements
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• G03H 1/04 - Processes or apparatus for producing holograms

Abstract

A system may include a first light source configured to generate a first light beam, where the first light beam is a pulsed light beam, where the first light beam is guided as a single transverse mode beam. A system may include a second light source configured to generate a second light beam, where the second light beam is a continuous-wave light beam. A system may include a hollow core optical fiber configured to propagate the first and second light beams. A system may include one or more optical elements to couple the first and second beams into the hollow core fiber.

IPC Classes  ?

• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding
• G02B 6/26 - Optical coupling means
• H04B 10/2507 - Arrangements specific to fibre transmission for the reduction or elimination of distortion or dispersion
• A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
• A61N 5/06 - Radiation therapy using light

Abstract

Various embodiments relate to a method for producing a metal-organic framework (MOF) having a desired redox conductivity and including redox-active linkers, having ω-alkyl-ferrocene groups, via de novo solvothermal synthesis. Various embodiments relate to a metal-organic framework (MOF) linker comprising an ω-alkyl-ferrocene group. Various embodiments relate to a metal-organic framework (MOF), having a first plurality of redox-active linkers, each having an ω-alkyl-ferrocene group. The MOF according to various embodiments, may further have one or more redox-inactive linkers. Various embodiments relate to materials, apparatuses, and components that include the MOF according to various embodiments. For example, various embodiments relate to thin-films, bulk powders, or electrodes.

IPC Classes  ?

• C07F 17/02 - Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
• C25B 11/048 - Organic compounds

Abstract

Here discloses an optical display system and an electronics device. The optical display system comprises: image-generating display; controllable polarization rotator module, which receives light from the image-generating display and outputs the light into polarized light with a first polarization and/or a second polarization under control; a first reflective lens, which reflects the polarized light with a first polarization to a pupil of an observer; and a second reflective lens, which reflects the polarized light with a second polarization to the pupil, wherein the first reflective lens and the second reflective lens have different optical powers to produce image planes at different depths.

IPC Classes  ?

• G02B 27/01 - Head-up displays
• G02B 27/12 - Beam splitting or combining systems operating by refraction only
• G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising

Abstract

A sensor may include one or more photonic lanterns, each including a waveguide structure with a single input waveguide at an input end and two or more output waveguides at an output end, where the two or more output waveguides of each of the one or more photonic lanterns are optically decoupled. A distribution of intensities of light exiting two or more output waveguides of each of the one or more photonic lanterns may correspond to a modal decomposition of input light coupled into the input waveguide of the corresponding one of the one or more photonic lanterns. The sensor may further include one or more spectrometers coupled to the two or more output waveguides of the one or more photonic lanterns to provide a wavelength-resolved modal decomposition of the input light.

IPC Classes  ?

• G01J 3/28 - Investigating the spectrum
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01J 3/14 - Generating the spectrumMonochromators using refracting elements, e.g. prism

Abstract

A ceria heterostructure may include one or more base materials and one or more ceria surface structures at least partially surrounding the one or more base materials, where defect states of the one or more ceria surface structures are reversibly controllable by controlling a stress on the one or more surface structures that is at least partially induced by the one or more base materials.

IPC Classes  ?

• C23C 16/40 - Oxides
• C23C 16/455 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for introducing gases into the reaction chamber or for modifying gas flows in the reaction chamber
• G01N 27/30 - Electrodes, e.g. test electrodesHalf-cells

Abstract

An optical imaging system and an imaging device are disclosed. The optical imaging system includes: a display assembly, which outputs lights of an image; a lens assembly, which enlarges the image; a polarization converter, wherein the polarization converter is a frequency-dependent polarization converter, which can convert the lights of a first frequency to a first polarization and convert the lights of a second frequency to a second polarization; and an aberration-correcting optical assembly, which is a polarization-dependent planar optics assembly.

IPC Classes  ?

• G02B 27/01 - Head-up displays
• G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for
• G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising

Abstract

A method for manufacturing a color-changing product using an electrical connectorization system including an ultrasonic welder includes providing a fabric to the electrical connectorization system where the fabric includes a plurality of color-changing fibers, providing a connection bus to the electrical connectorization system, and operating the electrical connectorization system to move the fabric and the connection bus into engagement with the ultrasonic welder to generate one or more welds between the connection bus and at least a subset of the plurality of color-changing fibers as the fabric and the connection bus pass the ultrasonic welder.

IPC Classes  ?

• D03D 1/00 - Woven fabrics designed to make specified articles

Abstract

A hollow core fiber (HCF) may include a solid tubular cladding structure extending in a longitudinal direction along a length of the HCF and one or more antiresonant (AR)structures extending in the longitudinal direction along the length of the HCF and located in an interior region of the cladding structure, where the one or more AR structures form a central hollow region providing a core region for guiding light. The HCF may further include a low-index coating at least partially surrounding the cladding structure, wherein a refractive index of the low-index coating is lower than a refractive index of the cladding structure to provide guiding of leakage light, where the leakage light includes at least light that decouples from the hollow central core.

IPC Classes  ?

• G02B 6/02 - Optical fibres with cladding
• C03B 37/027 - Fibres composed of different sorts of glass, e.g. fibre optics

Abstract

A prediction system may train a neural network model to analyze data to predict sentiments associated with the data and a measure of incompleteness of the data. The prediction system may obtain communication data regarding a communication session between a first device and a second device. The communication data is obtained via a network. The prediction system may provide the communication data as an input to the trained neural network model. The prediction system may determine, using the trained neural network model, a first set of sentiments associated with the first device and a second set of sentiments associated with the second device. The prediction system may determine, using the trained neural network model, a measure of incompleteness of the communication data based on the first set of sentiments and the second set of sentiments. The prediction system may perform an action based on the measure of incompleteness.

IPC Classes  ?

• G06F 40/242 - Dictionaries
• G06F 40/205 - Parsing

Abstract

A system can include a beamsplitter configured to be in optical communication with an optical input source configured to generate one or more input optical signals. The beamsplitter can be configured to split the one or more input optical signals into one or more seed optical signals configured to propagate along a first optical path, and one or more pump optical signals configured to propagate along a second optical path. The system can include a frequency divider in optical communication with the beamsplitter to receive the one or more seed optical signals. The frequency divider can be configured to divide optical frequencies of the one or more seed optical signals in half to provide one or more subharmonic seed optical signals. The system can include a beam combiner in optical communication with the frequency divider to receive the one or more subharmonic seed optical signals, and with the beamsplitter to receive the one or more pump optical signals. The beam combiner can be configured to combine at least one of the one or more pump optical signals and at least one of the one or more subharmonic seed optical signals to provide a combined optical signal. The system can include a nonlinear material in optical communication with the beam combiner to receive the combined optical signal. The nonlinear material can be configured to provide optical parametric amplification of the at least one of the one or more subharmonic seed optical signals of the combined optical signal.

IPC Classes  ?

• G02F 1/39 - Non-linear optics for parametric generation or amplification of light, infrared, or ultraviolet waves

Abstract

This invention relates to a biodegradable hydrophobic or omniphobic coating with tailorable properties for various applications. The technology's hydrophobic modifications, surface functionalization, and surface roughness modifications enable low contact angle hysteresis for easy roll-off and self-cleaning properties. The composite is based on polymer substrate(s) or functionalized polymer substrate(s), filler(s), inorganic(s), binder(s), Lycopodium, or a combination of materials. The Lycopodium may be functionalized with suitable end groups for better adhesion or to impart beneficial properties. The polymer(s) and other constituents may be deposited on the substrate by various methods including spin coating, dip coating, spray coating, sputter coating, electrospinning, solvent casting, or extrusion. Binders and chemicals are incorporated in suitable chronology with or without the solvents of choice.

IPC Classes  ?

• C08J 7/04 - Coating
• C09D 5/16 - Anti-fouling paintsUnderwater paints
• C09D 197/02 - Lignocellulosic material, e.g. wood, straw or bagasse
• C09D 201/00 - Coating compositions based on unspecified macromolecular compounds

Abstract

A method for motion estimation in CT systems is provided. The method includes dividing projection data, obtained by scanning a heart using the CT system, into a plurality of partial-angle-reconstruction (PAR) bins, reconstructing a plurality of PAR volumes from the PAR-binned projection data, obtaining, based on the plurality of reconstructed PAR volumes, a number of short-scan volumes, determining, based on the obtained number of short-scan volumes, a plurality of nodes throughout the heart, estimating, for each of the determined plurality of nodes, a plurality of model parameters of a motion model, and generating, based on the plurality of model parameters estimated for each of the plurality of nodes, parameters of a global motion model at each voxel of a volume of the heart. The method also includes reconstructing, based on the generated motion parameters of the global motion model at each voxel of the volume of the heart, a motion-compensated short-scan volume.

IPC Classes  ?

• G06T 7/246 - Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
• G06T 7/62 - Analysis of geometric attributes of area, perimeter, diameter or volume
• G06T 11/00 - 2D [Two Dimensional] image generation

Abstract

Described herein relates to a self-supervised reinforced learning (hereinafter “SSRL”) system for question-and-answer query systems that may include one or more initial steps to prime a neural network to prevent an agent from prematurely selecting an early path and method thereof. The SSRL method may also provide the agent with a lead for queries with a large action space, such that at least one existing reinforced learning system may be improved (e.g., accuracy). Additionally, to scale to larger datasets in which label generation for each training sample is infeasible, the SSRL system may include one or more steps of pretraining the dataset(s) with partial labels, which may be generated from a subset of a whole knowledge graph.

IPC Classes  ?

• G06N 5/02 - Knowledge representationSymbolic representation
• G06N 3/092 - Reinforcement learning

Abstract

A fastener gun or nail gun utilizes a propellant cartridge having a centerfire primer made from thermite. The thermite is made from alternating layers of metal oxide and reducing metal, and includes one or more layers of carbide-containing ceramic. The primer ignites a propellant which may be a conventional single base or double base smokeless powder, or which may be thermite having a structure similar to the thermite of the primer. The primer may be initiated mechanically or electrically. The fastener gun is capable of applying a level of force similar to the force applied by conventional propellant cartridges, while avoiding inhalation of lead particles by the operator of the fastener gun.

IPC Classes  ?

• B25C 1/16 - Cartridges specially adapted for impact toolsCartridge-and-nail units
• C06C 9/00 - Chemical contact ignitersChemical lighters
• F42B 5/16 - Cartridges, i.e. cases with propellant charge and missile characterised by composition or physical dimensions or form of propellant charge or powder

Abstract

Systems and devices for a self-interference cancelation scheme that allows for large numbers of delays while maintaining a small size and area. The main components of this scheme include AE delay line arrays (for re-constructing the interference to be subtracted); AE circulators (for providing isolation between the transmitter-to-antenna and antenna-to-receiver paths); and AE couplers (for tapping the signal from the transmit chain to the delay lines). Together, a fully micro-acoustic interference cancelation module is realized in thin-film piezoelectric-semiconductor heterostructures, which are usable in cellular communication devices, base stations, wireless communication modules, and similar transmission/reception systems.

IPC Classes  ?

• H04B 1/04 - Circuits
• H03H 9/42 - Time-delay networks using surface acoustic waves
• H04B 1/10 - Means associated with receiver for limiting or suppressing noise or interference

Abstract

A fastener gun or nail gun utilizes a propellant cartridge having a centerfire primer made from thermite. The thermite is made from alternating layers of metal oxide and reducing metal, and includes one or more layers of carbide-containing ceramic. The primer ignites a propellant which may be a conventional single base or double base smokeless powder, or which may be thermite having a structure similar to the thermite of the primer. The primer may be initiated mechanically or electrically. The fastener gun is capable of applying a level of force similar to the force applied by conventional propellant cartridges, while avoiding inhalation of lead particles by the operator of the fastener gun.

IPC Classes  ?

• B25C 1/16 - Cartridges specially adapted for impact toolsCartridge-and-nail units
• B25C 1/14 - Hand-held nailing toolsNail feeding devices therefor operated by combustion pressure generated by detonation of a cartridge acting on an intermediate plunger or anvil

Abstract

This disclosure provides a portable hemostatic bandage system, which comprises two formulations comprising siloxanes and blowing gas generating agents as well as a dual container device, optionally a dual syringe applicator, for in situ construction of a sponge-like polymer foam as hemostatic bandage material. Two formulations kept separately in a dual container device react instantly with each other when forced to mix, and as a result, decomposition of hydrogen peroxide occurs to generate a blowing gas O2 and heat, and consequently siloxane polymer curing occurs to form polymer foam inside the dual container device. When the blowing foam is applied to a bleeding wound, it forms a sponge plug within a few minutes to control hemorrhage. This portable hemostatic bandage system can be easily used at ambient temperatures, and it is a cost-effective method to control hemorrhage.

IPC Classes  ?

• A61L 15/26 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bondsDerivatives thereof

Abstract

Disclosed herein are engineered NK cells suppressed in the expression of T Cell Immunoreceptor with Ig And ITIM Domains (TIGIT) and uses thereof for treating cancers and infectious diseases.

IPC Classes  ?

• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 35/00 - Antineoplastic agents
• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells

Abstract

Photoluminescence and electroluminescence are essential characterization techniques for photovoltaics cells and modules. For electroluminescence, the main technical challenge is easily injecting current into the photovoltaic to cause luminescence. The technique described herein enables daylight electroluminescence imaging without the need for external power sources. For photoluminescence, characterization is performed on photovoltaic cells, modules, strings, and arrays in daylight and without temporary mounting of LED modulators. Instead, the modulation is performed using a permanent electronic module installed within the electric circuit on the DC side. This enables automation or triggering of modulation on demand, 100% inspection without changes in hardware configuration because the cells are never shaded and provides a path to high throughput imaging.

IPC Classes  ?

• H02S 50/15 - Testing of PV devices, e.g. of PV modules or single PV cells using optical means, e.g. using electroluminescence
• G06T 7/00 - Image analysis
• H04N 23/20 - Cameras or camera modules comprising electronic image sensorsControl thereof for generating image signals from infrared radiation only

Abstract

An optical display system and a head-mounted display electronics apparatus are disclosed. The optical display system comprises: an image-generating apparatus, which generates image light; and an image-viewing apparatus, which guides the image light to eyes of a viewer, wherein the image-viewing apparatus comprises an imaging optical assembly and a multifocal assembly placed, the multifocal assembly has at least two optical powers and is programmable to choose at least one of the optical powers at a given time.

IPC Classes  ?

• G02B 27/01 - Head-up displays
• G02B 3/10 - Bifocal lensesMultifocal lenses
• G02B 27/02 - Viewing or reading apparatus
• G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising
• G02B 27/42 - Diffraction optics
• G02B 30/25 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the stereoscopic type using polarisation techniques
• G02B 30/30 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving parallax barriers

Abstract

Described herein relates to a system of and method for providing and booking a personalized health-based travel itinerary. The invention may comprise an integrated travel platform which may be configured to present a score computed by a multifactorial AI based decision support algorithm which draws data sets from curated public and private data sources in real time basis. Additionally, the integrated travel platform may integrate an accommodation and/or an experience digital framework which may greatly increase utility and expand the user base for the integrated travel platform, while democratizing the travel industry. As such, the digital framework may allow travel accommodation and/or experience service providers to participate proactively and/or reach out to niche traveler profiles specific to at least one user based on the following, including but not limited to, interests, health conditions, family circumstances, cultural considerations, and/or experiences that travelers or traveler groups seek.

IPC Classes  ?

• G06Q 10/02 - Reservations, e.g. for tickets, services or events
• G06Q 50/14 - Travel agencies

Abstract

The present disclosure is directed to a multi-layered catalytic article (10) effective in selective oxidation of ammonia to nitrogen gas, the catalytic article comprising at least a top layer (11) comprising a selective catalytic reduction catalyst, a bottom layer (13) comprising an ammonia oxidation catalyst, and a substrate (15). The ammonia oxidation catalyst comprises platinum on a zeolite support. The present disclosure is also directed to a method of making the catalytic article, an emission treatment system for selectively oxidizing ammonia from an exhaust gas stream with the catalytic article, and a method for treating an exhaust stream containing ammonia with the emissions treatment system.

IPC Classes  ?

• B01D 53/94 - Chemical or biological purification of waste gases of engine exhaust gases by catalytic processes

Abstract

Described herein relates to a method for pre-processing files that can improve file compression rates of existing general-purpose lossless file compression algorithms, particularly for files on which traditional algorithms perform poorly. The elementary cellular automata (CA) pre-processing technique involves finding an optimal CA state that can be used to transform an original file into a format (i.e., an intermediary file) that is more amenable to compression than the original file format. This technique is applicable to multiple file types and may be used to enhance multiple compression algorithms. Evaluation on generated files, as well as samples selected from online text repositories, finds that the CA pre-processing technique improves compression rates by up to 4% and shows promising results for assisting in compressing data that typically induce worst-case behavior in standard compression algorithms.

IPC Classes  ?

• G06F 16/174 - Redundancy elimination performed by the file system
• H03M 7/30 - CompressionExpansionSuppression of unnecessary data, e.g. redundancy reduction

Abstract

The discovery of a clear correlation between the Anderson localization length and the dispersion properties of highly localized TALOF modes allowed us to demonstrate that the zero dispersion wavelength can be tuned over more than 300 nm within the same fiber by selected excitation of specific modes. This enabled apparatus and methods for generating tunable, multi-octave-spanning supercontinuum (SC) spectra in a bandwidth from 460 nm to 1750 nm. Associated applications are also presented.

IPC Classes  ?

• G02F 1/35 - Non-linear optics
• G02F 1/355 - Non-linear optics characterised by the materials used
• G02F 1/365 - Non-linear optics in an optical waveguide structure

Abstract

A phase-shifted longitudinally-chirped volume Bragg grating (PS-LCVBG) may be formed as a solid block of photosensitive material having a planar input face, where the photosensitive material includes a VBG formed as a periodic volumetric refractive index distribution characterized by a grating vector direction. A period of the VBG may longitudinally chirped to vary linearly along the grating vector direction. The VBG may further include a spatially-varying distribution of longitudinal phase shifts providing a spatially-varying distribution of reflectivity in a transverse plane normal to the grating vector direction, where light incident on the planar input face is at least partially reflected based on the spatially-varying distribution of reflectivity.

IPC Classes  ?

• G02B 5/32 - Holograms used as optical elements
• G02B 5/18 - Diffracting gratings
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• G03H 1/04 - Processes or apparatus for producing holograms

Abstract

The present disclosure relates to wound treatment and therapy and the promotion of tissue regeneration following injury. In particular, it relates to a microRNA-146a and nanoceria conjugate for improving wound healing and, in some embodiments, preventing adverse ventricular remodeling following myocardial infarction.

IPC Classes  ?

• A61K 33/24 - Heavy metalsCompounds thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/14 - Particulate form, e.g. powders
• A61K 31/728 - Hyaluronic acid
• A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
• A61K 47/55 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• C01F 17/235 - Cerium oxides or hydroxides
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Abstract

An optical isolator may include one or more rotated volume Bragg gratings (r-VBGs) within a volume of a material having an input face, where each of the r-VBGs reflects along a reflection path portions of input light propagating along an incidence vector through the input face that satisfies a Bragg condition for one or more selected wavelengths and has a polarization orthogonal to a diffraction plane formed by the associated grating vector and the incidence vector, and where each of the r-VBGs transmits remaining portions of the input light as transmitted light along a transmission path. The isolator may also include one or more polarization-controlling optics located along the transmission path configured to modify a polarization of return light propagating back along the transmission path towards the one or more r-VBGs, where the one or more r-VBGs reflect portions of the return light that satisfy the Bragg condition.

IPC Classes  ?

• G02B 5/32 - Holograms used as optical elements
• G01J 4/04 - Polarimeters using electric detection means

Abstract

A beam combiner may include one or more light sources providing two or more input beams along two or more incidence paths and one or more rotated volume Bragg gratings (r-VBGs), where each of the r-VBGs is formed as planes of refractive index variation with periodicity along a respective grating vector at a respective non-zero angle relative to a respective one of the incidence paths of a respective one of the input beams, where the r-VBGs direct the two or more input beams along a common output path through at least one of transmission or reflection via Bragg reflection, and where at least one of the r-VBGs reflects a portion of at least one of the input beams satisfying a Bragg condition and having a polarization normal to a diffraction plane formed by a respective incidence path and the respective grating vector.

IPC Classes  ?

• G02B 27/10 - Beam splitting or combining systems

Abstract

A spectrometer may include a rotated volume Bragg grating (r-VBG) within a volume of a material having an input face, where the r-VBG reflects portions of input light propagating through the input face that satisfies a Bragg condition for wavelengths within a spectral band, where a period of the r-VBG along the grating vector is chirped to vary along the grating vector to provide that the Bragg condition is satisfied for different wavelengths at different depths, and where a spectrum of the input light is spatially resolved in the reflected portions of the input light by the r-VBG. The spectrometer may further include a multi-pixel detector configured to receive the reflected portions of the input light from the r-VBG, where the multi-pixel detector is configured to output spectral data indicative of the spectrum of the input light within the spectral band.

IPC Classes  ?

• G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry

Abstract

A laser device may include two rotated volume Bragg gratings (r-VBGs), where periods of the two r-VBGs are chirped along the respective grating vectors to vary along the respective grating vectors, where the two r-VBGs are spatially separated along a separation direction oriented at a non-zero angle to the grating vectors, and a gain medium between the two r-VBGs. A first of the two r-VBGs may reflect portions of an input beam from a seed laser source propagating along an incidence direction as a spectrally-spread beam. The gain medium may amplify the spectrally-spread beam when pumped. A second of the two r-VBGs may reflect portions of the spectrally-spread beam satisfying the Bragg condition into the incidence direction, wherein the second r-VBG is positioned to provide that the spectrally-spread beam is spectrally recombined into an output beam.

IPC Classes  ?

• H01S 3/08 - Construction or shape of optical resonators or components thereof
• H01S 3/10 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
• H01S 3/106 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity

Abstract

A catalyst support structure may include a base material and a metal oxide support structure. The metal oxide support structure may be formed by loading a first concentration of precursors of a metal oxide onto the base material using incipient wetness impregnation (IWI) to form the catalyst support structure, performing a first calcination process on the catalyst support structure at a first temperature to produce first structures of the metal oxide, loading a second concentration of precursors of the metal oxide onto the catalyst support structure using IWI to at least partially cover the first structures of the metal oxide, and performing a second calcination process on the catalyst support structure at a second temperature lower than the first temperature to produce second structures of the metal oxide.

IPC Classes  ?

• B01J 37/02 - Impregnation, coating or precipitation
• B01J 23/42 - Platinum
• B01J 37/08 - Heat treatment
• B01J 37/16 - Reducing

Abstract

An optical isolator may include one or more rotated volume Bragg gratings (r-VBGs) within a volume of a material having an input face, where each of the r-VBGs reflects along a reflection path portions of input light propagating along an incidence vector through the input face that satisfies a Bragg condition for one or more selected wavelengths and has a polarization orthogonal to a diffraction plane formed by the associated grating vector and the incidence vector, and where each of the r-VBGs transmits remaining portions of the input light as transmitted light along a transmission path. The isolator may also include one or more polarization-controlling optics located along the transmission path configured to modify a polarization of return light propagating back along the transmission path towards the one or more r-VBGs, where the one or more r-VBGs reflect portions of the return light that satisfy the Bragg condition.

IPC Classes  ?

• G02B 5/18 - Diffracting gratings
• G02B 5/30 - Polarising elements
• G02B 6/02 - Optical fibres with cladding
• G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• G01J 3/18 - Generating the spectrumMonochromators using diffraction elements, e.g. grating

Abstract

A phase modulation device may include two rotated chirped volume Bragg gratings (r-VBGs), where the two r-VBGs are spatially separated along a separation direction oriented at a nonzero degree angle to the grating vectors, and further includes a phase modulator between the two r-VBGs with a spatially non-uniform phase distribution in a plane orthogonal to the separation direction. A first of the two r-VBGs may reflect portions of an input beam propagating towards the phase modulator as spectrally-spread beam. A second of the two r-VBGs may reflect portions of the spectrally-spread beam satisfying the Bragg condition into the incidence direction, where the second r-VBG is positioned to provide that the Bragg condition is satisfied for different wavelengths at different locations of the first r-VBG along the incidence direction to provide that the spectrally-spread beam is spectrally recombined into an output beam.

IPC Classes  ?

• G02B 5/18 - Diffracting gratings

Abstract

The disclosure describes a method of removing and/or replacing an organic ligand from a surface of metal oxide nanoparticles. The method involves mixing a sample of metal oxide nanoparticles comprising an organic ligand in a liquid comprising an organic phase and an aqueous phase, the aqueous phase comprising at least one stripping agent, wherein mixing occurs under conditions to cause the stripping agent to interact with the surface of the metal oxide nanoparticles; removing the aqueous phase from the organic phase following mixing; and optionally, drying the aqueous phase removed from the organic phase.

IPC Classes  ?

• A61K 9/51 - Nanocapsules
• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 33/24 - Heavy metalsCompounds thereof
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

A microcontroller coupled to sensors integrated into a physical toy for monitoring free play activity of a human subject wherein patterns in play activity sensed by the microcontroller are graphically visualized for identification of behavioral milestones, developmental progress and/or behavioral disorders. Specifically, accelerometers detect movement of toys which determine: (1) if the toy is being played with; and (2) the intensity in which the toy is moved. Pressure sensors detect the level and location in which a child may hold a toy. Synchronized with an audiovisual record of the play therapy session and a computer-generated avatar representation of the physical object, this data is integrated to find peak levels of behavior giving clinicians more efficient analytical tools.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/16 - Devices for psychotechnicsTesting reaction times
• A61M 21/00 - Other devices or methods to cause a change in the state of consciousnessDevices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
• A63H 3/00 - Dolls
• A63H 3/02 - Dolls made of fabrics or stuffed
• A63H 3/36 - Dolls DetailsAccessories
• A63H 33/04 - Building blocks, strips or similar building parts
• G01L 1/20 - Measuring force or stress, in general by measuring variations in ohmic resistance of solid materials or of electrically-conductive fluidsMeasuring force or stress, in general by making use of electrokinetic cells, i.e. liquid-containing cells wherein an electrical potential is produced or varied upon the application of stress

Abstract

A smart, human-centered technique that uses artificial intelligence and mixed reality to accelerate essential tasks of the inspectors such as defect measurement, condition assessment and data processing. For example, a bridge inspector can analyze some remote cracks located on a concrete pier, estimate their dimensional properties and perform condition assessment in real-time. The inspector can intervene in any step of the analysis/assessment and correct the operations of the artificial intelligence. Thereby, the inspector and the artificial intelligence will collaborate/communicate for improved visual inspection. This collective intelligence framework can be integrated in a mixed reality supported see-through headset or a hand-held device with the availability of sufficient hardware and sensors. Consequently, the methods reduce the inspection time and associated labor costs while ensuring reliable and objective infrastructure evaluation. Such methods offer contributions to infrastructure inspection, maintenance, management practice, and safety for the inspection personnel.

IPC Classes  ?

• G06T 7/00 - Image analysis
• G02B 27/01 - Head-up displays
• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
• G06T 7/11 - Region-based segmentation
• G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
• G06V 10/94 - Hardware or software architectures specially adapted for image or video understanding

Abstract

A system and method for disconnection tolerant network routing, termed Binary State Distance Vector Routing (BSDVR). BSDVR provides for unicast routing on partitioned networks by introducing binary state information for distance vector (DV) entries to compute unicast paths. In the presence of network partitions, BSDVR effectively avoids the count-to-infinity problem and operates with control overhead less than traditional DV routing by an order of magnitude, leading to much better convergence times for failures.

IPC Classes  ?

• H04L 45/12 - Shortest path evaluation
• H04L 45/00 - Routing or path finding of packets in data switching networks
• H04L 45/28 - Routing or path finding of packets in data switching networks using route fault recovery

Abstract

A spectrometer may include a rotated volume Bragg grating (r-VBG) within a volume of a material having an input face, where the r-VBG reflects portions of input light propagating through the input face that satisfies a Bragg condition for wavelengths within a spectral band, where a period of the r-VBG along the grating vector is chirped to vary along the grating vector to provide that the Bragg condition is satisfied for different wavelengths at different depths, and where a spectrum of the input light is spatially resolved in the reflected portions of the input light by the r-VBG. The spectrometer may further include a multi-pixel detector configured to receive the reflected portions of the input light from the r-VBG, where the multi-pixel detector is configured to output spectral data indicative of the spectrum of the input light within the spectral band.

IPC Classes  ?

• G02B 6/34 - Optical coupling means utilising prism or grating
• G02B 5/18 - Diffracting gratings
• G01J 3/28 - Investigating the spectrum
• G02F 1/07 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on electro-optical liquids exhibiting Kerr effect

Abstract

A beam combiner may include one or more light sources providing two or more input beams along two or more incidence paths and one or more rotated volume Bragg gratings (r-VBGs), where each of the r-VBGs is formed as planes of refractive index variation with periodicity along a respective grating vector at a respective non-zero angle relative to a respective one of the incidence paths of a respective one of the input beams, where the r-VBGs direct the two or more input beams along a common output path through at least one of transmission or reflection via Bragg reflection, and where at least one of the r-VBGs reflects a portion of at least one of the input beams satisfying a Bragg condition and having a polarization normal to a diffraction plane formed by a respective incidence path and the respective grating vector.

IPC Classes  ?

• G02B 5/18 - Diffracting gratings
• G02B 5/30 - Polarising elements
• G02B 6/02 - Optical fibres with cladding
• G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• G01J 3/18 - Generating the spectrumMonochromators using diffraction elements, e.g. grating

Abstract

A phase modulation device may include two rotated chirped volume Bragg gratings (r-VBGs), where the two r-VBGs are spatially separated along a separation direction oriented at a nonzero degree angle to the grating vectors, and further includes a phase modulator between the two r-VBGs with a spatially non-uniform phase distribution in a plane orthogonal to the separation direction. A first of the two r-VBGs may reflect portions of an input beam propagating towards the phase modulator as spectrally-spread beam. A second of the two r-VBGs may reflect portions of the spectrally-spread beam satisfying the Bragg condition into the incidence direction, where the second r-VBG is positioned to provide that the Bragg condition is satisfied for different wavelengths at different locations of the first r-VBG along the incidence direction to provide that the spectrally-spread beam is spectrally recombined into an output beam.

IPC Classes  ?

• G02B 6/34 - Optical coupling means utilising prism or grating
• G02B 5/18 - Diffracting gratings
• G01J 3/28 - Investigating the spectrum
• G02F 1/07 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on electro-optical liquids exhibiting Kerr effect

Abstract

A laser device may include two rotated volume Bragg gratings (r-VBGs), where periods of the two r-VBGs are chirped along the respective grating vectors to vary along the respective grating vectors, where the two r-VBGs are spatially separated along a separation direction oriented at a non-zero angle to the grating vectors, and a gain medium between the two r-VBGs. A first of the two r-VBGs may reflect portions of an input beam from a seed laser source propagating along an incidence direction as a spectrally-spread beam. The gain medium may amplify the spectrally-spread beam when pumped. A second of the two r-VBGs may reflect portions of the spectrally-spread beam satisfying the Bragg condition into the incidence direction, wherein the second r-VBG is positioned to provide that the spectrally-spread beam is spectrally recombined into an output beam.

IPC Classes  ?

• H01S 5/12 - Construction or shape of the optical resonator the resonator having a periodic structure, e.g. in distributed feedback [DFB] lasers
• G03H 1/02 - Holographic processes or apparatus using light, infrared, or ultraviolet waves for obtaining holograms or for obtaining an image from themDetails peculiar thereto Details
• H01S 3/067 - Fibre lasers

Abstract

Biologic interfacial tissue-engineered systems (BITES) disclosed here is a biomaterial platform to provide engineered human and/or animal skin-like constructs for study of biting and/or blood feeding behavior of mosquitoes as well as other insects and arthropods. Provided herein are use and methods of making for BITES, in particular use and methods of cellularized Capgel for BITES with human cells.

IPC Classes  ?

• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12M 1/00 - Apparatus for enzymology or microbiology

Abstract

A laser diagnostic device may include a beamsplitter to split one or more input pulses into one or more fundamental pulses and one or more perturbing pulses, one or more beam-combining optics to combine the fundamental and perturbing pulses at a detection plane, a detector including a solid-state material at the detection plane, and a controller. The controller may receive a detector signal from the detector is indicative of nonlinear absorption in the solid-state medium of the fundamental pulses that is perturbed by the perturbing pulses. The controller may further extract a temporal electric field waveform of the one or more input pulses from the detector signal and provide as an output at least one of the temporal electric field waveform, a spectrum, or a spectral phase of the one or more input pulses.

IPC Classes  ?

• G01R 29/12 - Measuring electrostatic fields
• G01J 3/443 - Emission spectrometry
• G02B 27/10 - Beam splitting or combining systems
• G02F 1/355 - Non-linear optics characterised by the materials used

Abstract

Compositions, methods, and kits relating to ultrasound targeted nanobubble compositions are disclosed. The nanobubble compositions comprise a hollow core containing at least one gas; at least one therapeutic agent disposed in the hollow core; a polymer shell encircling the hollow core; and at least one targeting agent incorporated in the polymer shell. Methods of producing and using the nanobubble compositions are also disclosed.

IPC Classes  ?

• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61K 9/51 - Nanocapsules
• A61K 38/18 - Growth factorsGrowth regulators
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 19/10 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Abstract

Various embodiments relate to compounds and methods useful for preventing or treating a cancer in a subject. The method may include administering to a subject a composition according to any of the embodiments described herein in an amount effective to inhibit metastatic activity or tumor growth in the subject.

IPC Classes  ?

• C07D 295/155 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• C07D 211/46 - Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Abstract

An alloy anode for a seawater based aqueous battery and a universal strategy for preparing anodes for use in seawater based aqueous batteries. Zn-M alloys (where M can be manganese or other transition metal) were prepared by co-electrodeposition in the presence of hydrogen bubble formation to produce a porous nanostructured alloy that can serve as an anode for a seawater based aqueous battery. Exemplary Zn—Mn alloy anodes achieved stability over thousands of cycles even under harsh electrochemical conditions, including testing in seawater-based aqueous electrolytes and using a high current density of 80 mA cm−2. The anode design strategy allows for the production of durable electrodes for aqueous batteries and other applications.

IPC Classes  ?

• H01M 4/42 - Alloys based on zinc
• H01M 4/04 - Processes of manufacture in general
• H01M 10/36 - Accumulators not provided for in groups
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

A multi-stage draw tower may include two or more draw furnaces associated with two or more draw stages and one or more pullers to draw the preform through the two or more draw stages. The two or more draw furnaces and the one or more pullers are configured to progressively decrease a diameter of a preform through one or more intermediate diameters to provide a fiber with a selected final diameter in a single draw process. The fiber may correspond to a hollow-core optical fiber or a solid-core fiber.

IPC Classes  ?

• C03B 37/012 - Manufacture of preforms for drawing fibres or filaments
• C03B 37/027 - Fibres composed of different sorts of glass, e.g. fibre optics
• C03B 37/029 - Furnaces therefor

Abstract

A method is for operating a phased array. The method includes operating circuity coupled between first and second electrically conductive contacts to apply a voltage signal between the first and second electrically conductive contacts, change the voltage signal to selectively set phase change between IR radiation emitted from adjacent elliptical holes to emit the IR radiation at an angle from normal, and change the voltage signal to selectively set a frequency range of the IR radiation.

IPC Classes  ?

• G02F 1/29 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the position or the direction of light beams, i.e. deflection

Abstract

Disclosed herein are compositions and uses thereof for treating cancers.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 35/00 - Antineoplastic agents
• C12Q 1/6851 - Quantitative amplification
• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

In accordance with at least one aspect of this disclosure, a thermochromic window can include a first transparent layer, a second transparent layer, and a thermochromic fiber layer sandwiched between the first transparent layer and the second transparent layer. In certain embodiments, the thermochromic fiber layer may be embedded in the second transparent layer. The thermochromic window can be configured to selectively absorb or reflect infrared radiation (IR) as a function of a critical temperature.

IPC Classes  ?

• C03C 17/00 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating
• C03C 17/42 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating of an organic material and at least one non-metal coating

Abstract

A hybrid analog and digital computational system is created by receiving equations in which a set of solution values is unknown. A residual iterative algorithm is implemented to solve the set of solution values for the equations. The residual iterative algorithm includes an outer update loop computed using a digital computing device with a set of residue values initially set to a first initial value and a set of solution update values set to a second initial value. The residual iterative algorithm includes an inner residual loop, which is iteratively computed using an analog accelerator until one or more inner residual loop stopping criteria is met and returning the set of solution update values. Next, the set of solution updates are used to update the set of residue values and a range of a next set of solution update values, thereby adjusting a computational precision of the inner residual loop.

IPC Classes  ?

• G06J 1/00 - Hybrid computing arrangements

Abstract

An optical display system and an electronics apparatus are disclosed. The optical display system comprises: a display unit, which generate a first image light and a second image light, wherein the first image light is in a first polarization state and the second image light is in a second polarization state and the first image light and the second image light are generated by a same display panel; a resolution enhancement optic unit, which enhances the resolution of the first image light with respect to the second image light; and a magnifying optic unit, which magnify the first and second image lights from the resolution enhancement optic unit.

IPC Classes  ?

• G02B 27/01 - Head-up displays
• G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
• G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising