09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
35 - Advertising and business services
36 - Financial, insurance and real estate services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Digital dashboard software; reporting software; digital instruments; detectors; sensors; digital sensors; digital controllers; multimedia instruments; process control instruments; platform software; reporting platform software; information technology equipment; educational apparatus; instructional apparatus; computer programs; computer software; software; downloadable computer software for blockchain technology; software for artificial intelligence, machine learning models and predictive analytics on carbon emissions management and reporting; software for data authentication via blockchain; software for certification of data via blockchain; software for data storage via blockchain; software for analysing blockchain; software for blockchain analytics; data processing software; data management software; software for data analysis; analytical software; decision-making software; software for data clustering; software for monitoring carbon emissions; software in the field of carbon offsetting; software for monitoring carbon emissions of a commercial entity; software for monitoring carbon offsetting performance; platform software for reporting carbon emissions or carbon offsetting performance; ESG (environmental, social and governance), sustainability and triple bottom line reporting software; digital dashboard software for reporting carbon emissions or carbon offsetting performance; software for monitoring businesses against sustainable development goals; software for environmental, social and governance services; downloadable publications; electronic publications, downloadable; downloadable case studies for illustrative purposes; parts and fittings for all of the aforementioned. Research publications; educational publications; publications for disseminating research information; instructional and teaching material; printed matter; advertising materials; brochures; printed case studies for illustrative purposes and white papers. Business management; Business consultancy; Business information; Business analysis; Business assistance; Business consulting; Business consultation; Business information services; Collecting business information; Consultancy (Professional business -); Professional business consultancy; Business advisory services; Strategic business consultancy; Collecting business statistics; Strategic business analysis; Business management services; Business consultancy services; Business organisation advice; Business organisation consultancy; Business management consulting; business management of logistics for others; supply chain management services; consultancy in triple bottom line accounting for businesses; business consultancy in ESG (environmental, social and governance) and sustainability strategy development for businesses; Accounting; Economic forecasting; Development of business organization strategies relating to corporate social responsibility; provision of advice, information and consultancy relating to all of the aforementioned. Brokerage of carbon offsets; brokerage of carbon credits; financial grant services; advice relating to accessing and eligibility of environmental grants and funds; provision of advice, information and consultancy relating to all of the aforementioned. Educational services; Training provision, Education provision; educational services for managerial and leadership staff; Education services in the nature of courses at the university level; education relating to data analysis; education relating to logistics and supply chain management; education relating to carbon offsetting; electronic publications (not downloadable); electronic online publications; electronic case studies for illustrative purposes (non-downloadable); Non-downloadable electronic online case studies and podcasts for illustrative purposes; provision of advice, information and consultancy relating to all of the aforementioned. Research in the reduction of carbon emissions; Greenhouse gas emission measuring and analysis; Technical research in the field of carbon offsetting; consultancy in the field of carbon offsetting; Research in the field of climate change; Provision of information relating to technological research; provision of information relation to carbon offsetting research; Providing scientific information, advice and consultancy relating to net zero scope 3 emissions; Providing scientific information, advice and consultancy relating to carbon offsetting; Consultation in environment protection; Design and development of computer software; Development of computer programs and licenses for analysis of exhaust gas emissions; Digital dashboard software as a service; reporting software as a service; platform as a service; reporting platform as a service; software as a service; blockchain as a service; software as a service for blockchain technology; software as a service for data authentication via blockchain; software as a service for certification of data via blockchain; software as a service for data storage via blockchain; software as a service for analysing blockchain; software as a service for blockchain analytics; blockchain analytics services; data processing software as a service; data management software as a service; software as a service for data analysis; analytical software as a service; decision-making software as a service; Providing temporary use of non-downloadable predictive analytics and machine learning software; software as a service for data clustering; technical data analysis services; technical data analytics services; software as a service for monitoring carbon emissions; software as a service in the field of carbon offsetting; software as a service for monitoring carbon emissions of a commercial entity; software as a service for monitoring carbon offsetting performance; platform as a service for reporting carbon emissions or carbon offsetting performance; digital dashboard software as a service for reporting carbon emissions or carbon offsetting performance; software as a service for monitoring businesses against sustainable development goals; software as a service for environmental, social and governance services; provision of advice, information and consultancy relating to all of the aforementioned.
2.
PHOTOCATALYTIC CONVERSION OF CARBON DIOXIDE AND WATER INTO HYDROCARBONS
The present invention relates to photocatalytic materials for use in the conversion of CO2 to non-CO2 carbon containing products. The photocatalytic materials comprise a metal nanofiber and a carbon-based nanostructure bound to the surface of the metal nanofiber. Methods for preparing such materials are described, as well as their use in the conversion of CO2 to non-CO2 carbon containing products. For example, the photocatalytic materials of the invention may be used to convert CO2 to methanol and/or ethanol with high conversion rates.
C07C 29/156 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used containing iron group metals, platinum group metals, or compounds thereof
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
There is provided a product comprising a suture thread which, prior to being used to form a surgical suture, is in a stressed state which gives the suture thread a tendency to undergo lengthwise viscoelastic contraction. The suture thread undergoes viscoelastic contraction when in use as a surgical suture and this may promote wound healing to a greater extent than a conventional suture thread which does not undergo viscoelastic contraction.
A heat pump system having a common refrigerant flow path split coupled to heating mode first and second refrigerant streams. In the common refrigerant flow path, a compressor is coupled to receive refrigerant from the heating mode first refrigerant stream and the heating mode second refrigerant stream. A refrigerant-to-refrigerant heat exchanger couples heat between the heating mode first refrigerant stream and the heating mode second refrigerant stream. A first refrigerant-air heat exchanger and a second refrigerant-air heat exchanger in a second air flow conduit is coupled to receive a first air flow from a first refrigerant-air heat exchanger in a first air flow conduit.
A heat exchanger apparatus includes at least one metal sheet with a corrugated surface, fabric covering at least a part of one surface of the at least one metal sheet to promote evaporation, and a wetting agent in the fabric to promote wetting of the fabric, the wetting agent also acting as an anti-microbial agent.
F28C 1/00 - Direct-contact trickle coolers, e.g. cooling towers
F28D 3/00 - Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium flows in a continuous film, or trickles freely, over the conduits
F28F 3/02 - Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations
F28F 25/08 - Splashing boards or grids, e.g. for converting liquid sprays into liquid filmsElements or beds for increasing the area of the contact surface
The present invention provides a delivery matrix comprising a carbohydrate derivative and at least one semiochemical for trapping and/or attracting and/or deterring at least one aquatic organism. The present invention provides a method for trapping and/or attracting a crustacean, said method comprising delivering an effective amount of specific semiochemicals.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
University services; courses of instruction in the
humanities, social sciences, law, pure sciences, applied
sciences, engineering, technology, medicine and education;
library services; arranging and conducting educational
conferences, exhibitions and seminars; preparation of
reports and provision of information relating to all the
aforesaid services; all included in this class; university
services; courses of instruction in the humanities, social
sciences, law, pure sciences, applied sciences, engineering,
technology, medicine and education; library services;
arranging and conducting educational conferences,
exhibitions and seminars; educational research on the
academic subject of accountancy; research in the field of
education; educational research on the academic subject of
law; preparation of reports and provision of information
relating to all the aforesaid services; all included in this
class. Research and consultancy services, all relating to science,
technology, and engineering; research and development of
medicines; computer design and development, computer
programming, design of computer software and hardware,
chemical research, biomedical research, mechanical research,
product research and engineering research, physics research;
chemical analysis, chemical laboratory research services,
laboratory services; geological research; research in the
field of fisheries; nursing and physics research, all
relating to medicine; mathematical research services;
research relating to sociology and social anthropology;
provision of information and advisory and consulting
services, all relating to the aforesaid services; all
included in this class.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
University services; courses of instruction in the
humanities, social sciences, law, pure sciences, applied
sciences, engineering, technology, medicine and education;
library services; arranging and conducting educational
conferences, exhibitions and seminars; preparation of
reports and provision of information relating to all the
aforesaid services; research in the field of education;
educational research on the academic subject of accountancy;
educational research on the academic subject of law;
educational research on the academic subject of sociology
and social anthropology; all included in this class. Research and consultancy services, all relating to science,
technology, and engineering; research and development of
medicines; computer design and development, computer
programming, design of computer software and hardware,
chemical research, biomedical research, mechanical research,
product research and engineering research, physics research;
chemical analysis, chemical laboratory research services,
laboratory services; geological research; research in the
field of fisheries; nursing and physics research, all
relating to medicine; mathematical research services;
provision of information and advisory and consultancy
services, all relating to the aforesaid services; all
included in this class.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
University services, namely, teaching, training, tutoring, and courses of instruction at the undergraduate, graduate, and postgraduate level; providing courses of instruction in the humanities, social sciences, law, pure sciences, applied sciences, engineering, technology, medicine, and education; library services; arranging and conducting educational conferences, exhibitions, and seminars in the fields of humanities, social sciences, law, pure sciences, applied sciences, engineering, technology, medicine, and education; provision of information relating to all the aforesaid services; research in the field of education; provision of information relating to all the aforesaid services Scientific research; scientific consultancy in the field of development of medicines and medical devices; technological research and consultancy in the fields of computer design and development and design and development of computer hardware and software; research and consultancy services, in the field of engineering; research and development of medicines; computer design and development, computer programming, design of computer software and hardware, chemical research, biomedical research, mechanical research, product research and engineering research, physics research; chemical analysis, chemical laboratory research services; laboratory services, namely, scientific and medical laboratory services; geological research; research in the field of fisheries; nursing and physics research, all relating to medicine; mathematical research services, namely, scientific research in the field of mathematics; scientific research relating to sociology and social anthropology; provision of information and advisory and consultancy services, all relating to the aforesaid services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
University services, namely, teaching, training, tutoring, and courses of instruction at the undergraduate, graduate, and postgraduate level; providing courses of instruction in the humanities, social sciences, law, pure sciences, applied sciences, engineering, technology, medicine, and education; library services; arranging and conducting educational conferences, exhibitions, and seminars in the fields of humanities, social sciences, law, pure sciences, applied sciences, engineering, technology, medicine, and education; provision of information relating to all the aforesaid services; research in the field of education Scientific research; scientific consultancy in the field of development of medicines and medical devices; technological research and consultancy in the fields of computer design and development and design and development of computer hardware and software; research and consultancy services in the field of engineering; research and development of medicines; computer design and development, computer programming, design of computer software and hardware, chemical research, biomedical research, mechanical research, product research and engineering research, physics research; chemical analysis, chemical laboratory research services; laboratory services, namely, scientific and medical laboratory services; geological research; research in the field of fisheries; nursing and physics research, all relating to medicine; mathematical research services, namely, scientific research in the field of mathematics; provision of information and advisory and consultancy services, all relating to the aforesaid services
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
45 - Legal and security services; personal services for individuals.
Goods & Services
Satellite processors; Software; AI software; Data processing software; Artificial intelligence software; Machine learning software for analysis; Machine learning software. Sea state forecasting; Collection of information relating to sea state; Provision of sea state information for shipping; Sea state information; Sea state research; Engineering consultancy; Scientific consultancy; Environmental consultancy services; Software consulting services; Consultancy (Computer software -); Forecasting (Weather -); Weather forecasting; Weather forecasting services; Providing weather information; Weather information services; Software development; Maintenance of software; Maintenance of data processing software; Updating of software; Development of software; Development and testing of computing methods, algorithms and software; Software as a service [SaaS] featuring software for machine learning; Consulting services in the field of software as a service [SaaS]; Scientific analysis; Scientific research and analysis; Technical data analysis; Scientific risk assessment; Meteorological research; Meteorological information; Meteorological forecasting; Meteorological information services; Collection of information relating to meteorology; Provision of meteorological information for shipping; Provision of meteorological information; Provision of weather information for shipping; Providing meteorological information; Provision of weather information. Granting of software licenses; Licensing of software; Granting of software licences; Granting of licences on intellectual property; Software licensing.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
45 - Legal and security services; personal services for individuals.
Goods & Services
Satellite processors; Software; AI software; Data processing software; Artificial intelligence software; Machine learning software for analysis; Machine learning software. Sea state forecasting; Collection of information relating to sea state; Provision of sea state information for shipping; Sea state information; Sea state research; Engineering consultancy; Scientific consultancy; Environmental consultancy services; Software consulting services; Consultancy (Computer software -); Forecasting (Weather -); Weather forecasting; Weather forecasting services; Providing weather information; Weather information services; Software development; Maintenance of software; Maintenance of data processing software; Updating of software; Development of software; Development and testing of computing methods, algorithms and software; Software as a service [SaaS] featuring software for machine learning; Consulting services in the field of software as a service [SaaS]; Scientific analysis; Scientific research and analysis; Technical data analysis; Scientific risk assessment; Meteorological research; Meteorological information; Meteorological forecasting; Meteorological information services; Collection of information relating to meteorology; Provision of meteorological information for shipping; Provision of meteorological information; Provision of weather information for shipping; Providing meteorological information; Provision of weather information. Granting of software licenses; Licensing of software; Granting of software licences; Granting of licences on intellectual property; Software licensing.
A heat pump system with a refrigerant flow path comprising, in the heating mode of operation: a compressor coupled to receive refrigerant from a heating mode first refrigerant stream and a heating mode second refrigerant stream of the refrigerant flow path; the condenser coupled to receive refrigerant from the compressor; and a heat exchanger for transferring heat between the heating mode first refrigerant stream and the heating mode second refrigerant stream, wherein the heating mode first refrigerant stream comprises: the first expansion valve coupled to receive refrigerant from the condenser; the first evaporator coupled to receive refrigerant from the first expansion valve; and the heat exchanger coupling the heating mode first refrigerant stream from the first evaporator to the compressor, wherein the heating mode second refrigerant stream comprises: the second expansion valve; the heat exchanger coupling the heating mode second refrigerant stream from the condenser to the second expansion valve; and the second evaporator being coupled to communicate refrigerant from the second expansion valve to the compressor, wherein the first evaporator is in a first air flow conduit with a first air inlet for receiving a first air flow, and the second evaporator is in a second air flow conduit coupled to receive the first air flow.
A thermal storage tank divided into a first and second chamber by a partition, wherein the partition has a partition aperture for the flow of fluid from the first chamber to the second chamber, and wherein a heat exchanger is provided within the first chamber for transferring heat from a heat source to fluid within the first chamber, and a thermal storage system, wherein the second chamber has a volume that is at least twice the volume of the first chamber, and wherein the first chamber contains one or more outlet ports and one or more inlet ports and the second chamber contains one or more outlet ports.
The present invention provides a delivery matrix comprising a carbohydrate derivative and at least one semiochemical for trapping and/or attracting and/or deterring at least one aquatic organism. The present invention provides a method for trapping and/or attracting a crustacean, said method comprising delivering an effective amount of specific semiochemicals.
The present invention provides a delivery matrix comprising a carbohydrate derivative and at least one semiochemical for trapping and/or attracting and/or deterring at least one aquatic organism. The present invention provides a method for trapping and/or attracting a crustacean, said method comprising delivering an effective amount of specific semiochemicals.
There is provided a product comprising a suture thread which, prior to being used to form a surgical suture, is in a stressed state which gives the suture thread a tendency to undergo lengthwise viscoelastic contraction. The suture thread undergoes viscoelastic contraction when in use as a surgical suture and this may promote wound healing to a greater extent than a conventional suture thread which does not undergo viscoelastic contraction.
A method of manufacturing a storage device for storing information, apparatus for storing information, an optical memristor device and a memory cell are disclosed. A method comprises providing at least one first electrode and at least one further electrode and providing each of at least one region of a first material between, and in electrical connection with, a respective first electrode and a further electrode whereby said step of providing at least one region comprises providing in the first material, a plurality of changeable particles that have charge storage capacity and at least one electrical property that is reversibly changeable responsive to absorption of incident electromagnetic radiation.
There is provided a product comprising a suture thread which, prior to being used to form a surgical suture, is in a stressed state which gives the suture thread a tendency to undergo lengthwise viscoelastic contraction. The suture thread undergoes viscoelastic contraction when in use as a surgical suture and this may promote wound healing to a greater extent than a conventional suture thread which does not undergo viscoelastic contraction.
A61L 17/08 - At least partly resorbable materials of animal origin, e.g. catgut, collagen
A61L 17/14 - Post-treatment to improve physical properties
21.
Radioactivity detection in a target fluid in a fluid communication passageway with a region of scintillator material and a solid-state light-sensor element
The present invention relates to a method and apparatus for detecting radioactivity. In particular, but not exclusively, the present invention relates to the detection of radioactivity in a target fluid in a fluid communication passageway using a region of scintillator material (130) to provide light responsive to the presence of radioactive material and at least one silicon photomultiplier (SiPM) (150) for providing an output signal responsive to the light provided by the scintillator material.
The invention relates to a heat exchanger apparatus comprising at least one metal sheet (10) (e.g. aluminium), and preferably a plurality in a stack. Each metal sheet (10) has a corrugated surface, with fabric covering at least a portion of one surface of the metal sheet to promote evaporation. A wetting agent (e.g. LiCl/Polyvinyl-Alcohol (PVA) solution) is provided in the fabric to promote wetting of the fabric, and also acts as an anti-microbial agent. The fabric preferably covers all of the corrugated surface, and two planar portions are provided above and below the corrugated surface respectively. In use, the heat exchanger apparatus is disposed with a long side vertical and the corrugated surface is disposed on a middle portion, the upper planar portion is contiguous with an air outlet, and/or the lower planar portion is contiguous with an air inlet. In a preferred embodiment, the corrugated surface has in cross-section a profile of a periodic waveform, wherein the peak-to-peak distance is 11.6 mm, the amplitude is 2.5 mm, and corrugations intersect the plane of the heat exchanger apparatus at an angle to that plane of 50 degrees. Also disclosed are a cooling system incorporating the heat exchanger apparatus and methods of operating the cooling system, involving intermittently operating a water supply system for the application of water to the fabric, and/or, recirculating water from a water sump using the water supply system.
F28F 3/02 - Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations
F28F 25/08 - Splashing boards or grids, e.g. for converting liquid sprays into liquid filmsElements or beds for increasing the area of the contact surface
F28D 3/00 - Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium flows in a continuous film, or trickles freely, over the conduits
C09K 19/10 - Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing at least two benzene rings
C09K 19/32 - Non-steroidal liquid crystal compounds containing condensed ring systems, i.e. fused, bridged or spiro ring systems
C09K 19/34 - Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
24.
ARGININE METHYLATION INHIBITOR FOR TREATING OR PREVENTING CARDIOVASCULAR DISEASE
The invention relates to the treatment and/or prevention of cardiovascular disease, for example thromboembolic conditions, such as atherothrombotic disease. In particularly, the invention relates to an arginine methylation inhibitor ('ArgMe' inhibitor) for use in the treatment and/or prevention of cardiovascular disease such as thromboembolic conditions (for example atherothrombotic disease).
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/17 - Amides, e.g. hydroxamic acids having the group N—C(O)—N or N—C(S)—N, e.g. urea, thiourea, carmustine
A61K 31/34 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/4355 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
A61K 31/53 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
Embodiments of the present invention relate to microfluidic devices and systems comprising such devices for use in the determination of sample characteristics. Certain embodiments relate to methods for determining one or more characteristics of a sample comprising a compound for in vivo use. Aptly, certain embodiments of the present invention relate to devices and methods for assessing radiopharmaceuticals and their suitability for administration to a patient in need thereof.
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
G01N 33/94 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving narcotics
The invention relates to a heat exchanger apparatus comprising at least one metal sheet (10) (e.g. aluminium), and preferably a plurality in a stack. Each metal sheet (10) has a corrugated surface, with fabric covering at least a portion of one surface of the metal sheet to promote evaporation. A wetting agent (e.g. LiCl/Polyvinyl-Alcohol (PVA) solution) is provided in the fabric to promote wetting of the fabric, and also acts as an anti-microbial agent. The fabric preferably covers all of the corrugated surface, and two planar portions are provided above and below the corrugated surface respectively. In use, the heat exchanger apparatus is disposed with a long side vertical and the corrugated surface is disposed on a middle portion, the upper planar portion is contiguous with an air outlet, and/or the lower planar portion is contiguous with an air inlet. In a preferred embodiment, the corrugated surface has in cross-section a profile of a periodic waveform, wherein the peak-to-peak distance is 11.6 mm, the amplitude is 2.5 mm, and corrugations intersect the plane of the heat exchanger apparatus at an angle to that plane of 50 degrees. Also disclosed are a cooling system incorporating the heat exchanger apparatus and methods of operating the cooling system, involving intermittently operating a water supply system for the application of water to the fabric, and/or, recirculating water from a water sump using the water supply system.
F28F 25/08 - Splashing boards or grids, e.g. for converting liquid sprays into liquid filmsElements or beds for increasing the area of the contact surface
F28C 1/00 - Direct-contact trickle coolers, e.g. cooling towers
F28D 3/00 - Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium flows in a continuous film, or trickles freely, over the conduits
F28F 3/02 - Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations
Certain embodiments of the present invention relate to a system and a method for producing a radiopharmaceutical, wherein the system is formed from and/or provides a microfluidic flow system. In certain embodiments, the system comprises a radioisotope isolation module, a radiopharmaceutical production module, a purification module and a quality control module.
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
C07B 59/00 - Introduction of isotopes of elements into organic compounds
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
G01N 33/60 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances involving radioactive labelled substances
G01N 30/00 - Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
28.
Method for separation of radioactive sample using monolithic body on microfluidic chip
The present invention relates to monolithic bodies, uses thereof and processes for the preparation thereof. Certain embodiments of the present invention relate to the use of a monolithic body in the preparation of a radioactive substance, for example a radiopharmaceutical, as part of a microfluidic flow system and a process for the preparation of such a monolithic body.
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
B01J 39/26 - Cation exchangers for chromatographic processes
B01J 41/20 - Anion exchangers for chromatographic processes
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
B01D 15/32 - Bonded phase chromatography, e.g. with normal bonded phase, reversed phase or hydrophobic interaction
B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
B01J 20/10 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
B01J 20/30 - Processes for preparing, regenerating or reactivating
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mouldApparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
G01N 30/96 - Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography using ion-exchange
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
B29K 105/00 - Condition, form or state of moulded material
B29K 709/00 - Use of inorganic materials not provided for in groups , for preformed parts, e.g. for inserts
The present invention relates to a method and apparatus for detecting radioactivity. In particular, but not exclusively, the present invention relates to the detection of radioactivity in a target fluid in a fluid communication passageway using a region of scintillator material (130) to provide light responsive to the presence of radioactive material and at least one silicon photomultiplier (SiPM) (150) for providing an output signal responsive to the light provided by the scintillator material.
Compositions are disclosed herein that include macrocycle derivatives incorporating bridged macrocycles. Also disclosed are methods of producing and using the compositions.
The invention provides photopolymerisable or photocrosslinkable reactive mesogen for forming a hole- transporting or light emitting polymer network, said mesogen having the structure (III) wherein M is a chromophoric aromatic or heterocyclic moiety; A1 and A2 are carbazole groups substituted in the 3-position of the carbazole ring, and may be the same or different; S1 and S2 are spacers, and may be the same or different; B1 and B2 are polymerisable groups, and may be the same or different; and m and n are independently integers from 1 to 10. The invention also provides a material for forming a light emitting or charge transporting polymer network comprising the photopolymerisable or photocrosslinkable reactive mesogen, a charge transporting or light emitting polymer network which is obtained by polymerisation or crosslinking of the mesogen, a process for the preparation of the polymer via photopolymerisation or photocrosslinking of suitable end-groups of the mesogen, a device comprising a polymer layer formed from the charge transporting or light emitting polymer network, a process for applying a charge transporting or light emitting polymer network to a surface and a backlight or display comprising a charge transporting or light emitting polymer network.
C09K 19/04 - Liquid crystal materials characterised by the chemical structure of the liquid crystal components
H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
H01L 51/50 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for light emission, e.g. organic light emitting diodes (OLED) or polymer light emitting devices (PLED)
H05B 33/14 - Light sources with substantially two-dimensional radiating surfaces characterised by the chemical or physical composition or the arrangement of the electroluminescent material
C09K 19/32 - Non-steroidal liquid crystal compounds containing condensed ring systems, i.e. fused, bridged or spiro ring systems
C09K 19/34 - Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
C07D 333/06 - Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
C08F 2/48 - Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
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Publications in electronic format; Educational software; Downloadable publications. Printed matter; Periodicals; Magazines; Educational publications; Educational books; Printed lectures; Instructional and teaching materials; Posters; Paintings; Photographs; Printed reports; Printed research reports; Computer manuals; Brochures; Advertising publications; Teaching manuals; Instructional manuals; Prospectuses. Preparing business reports; Advertising; Business management services; Business administration services; Office functions; Provision of business information; Business consultancy services; Business analysis, research and information services; Business risk assessment services; Business research; Business information and research services; Supply chain management services; Business auditing. University services; University education services; Education examination; Education; Education services; Education information; Educational consultancy; Educational instruction; Educational seminars; Educational research; Training and education services; Education, teaching and training; Dissemination of educational material; Publishing of educational material; Organising of competitions for education; Arranging of educational events; Organisation of educational events; Conducting of educational events; Seminars; Arranging and conducting seminars; Arranging and conducting of lectures; Instructional and training services; Publication and editing of printed matter; Educational research; Teaching; Teaching services; Providing courses of instruction; Cultural activities; Cultural services; Conducting of cultural events; Arranging of cultural events; Education and instruction. Research services; quality assurance consultancy; Providing quality assurance services; Process monitoring for quality assurance; Quality control; Certification [quality control]; Research and development services; Quality control services; Laboratory services. Reviewing standards and practices to assure compliance with laws and regulations; Providing information on issues concerning human rights.
09 - Scientific and electric apparatus and instruments
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09 - Scientific and electric apparatus and instruments
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09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
35 - Advertising and business services
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Publications in electronic format; Educational software; Downloadable publications. Printed matter; Periodicals; Magazines; Educational publications; Educational books; Printed lectures; Instructional and teaching materials; Posters; Paintings; Photographs; Printed reports; Printed research reports; Computer manuals; Brochures; Advertising publications; Teaching manuals; Instructional manuals. Preparing business reports; Advertising; Business management services; Business administration services; Office functions; Provision of business information; Business consultancy services; Business analysis, research and information services; Business risk assessment services; Research (Business -); Business research; Business information and research services. University services; University education services; Education examination; Education; Education services; Education information; Educational consultancy; Educational instruction; Educational seminars; Educational research; Education and instruction; Training and education services; Education, teaching and training; Publication of educational texts; Dissemination of educational material; Publishing of educational material; Organising of competitions for education; Arranging of educational events; Organisation of educational events; Conducting of educational events; Seminars; Arranging and conducting seminars; Arranging and conducting of lectures; Instructional and training services; Publication and editing of printed matter; Educational research; Teaching; Teaching services; Providing courses of instruction; Cultural activities; Cultural services; Conducting of cultural events; Arranging of cultural events; Library services; Arranging of courses of instruction; Research in the field of education; Consultancy services relating to academic subjects. Quality assurance consultancy; Providing quality assurance services; Process monitoring for quality assurance; Quality control; Certification [quality control]; Research and development services; Quality control services; Laboratory services; Research services. Reviewing standards and practices to assure compliance with laws and regulations; Providing information on issues concerning human rights.
36.
Wilberforce Institute for the Study of Slavery and Emancipation
09 - Scientific and electric apparatus and instruments
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35 - Advertising and business services
41 - Education, entertainment, sporting and cultural services
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Publications in electronic format; Educational software; Downloadable publications. Printed matter; Periodicals; Magazines; Educational publications; Educational books; Printed lectures; Instructional and teaching materials; Posters; Paintings; Photographs; Printed reports; Printed research reports; Computer manuals; Brochures; Advertising publications; Teaching manuals; Instructional manuals. Preparing business reports; Advertising; Business management services; Business administration services; Office functions; Provision of business information; Business consultancy services; Business analysis, research and information services; Business risk assessment services; Business research; Business information and research services; Supply chain management services; Business auditing. University services; University education services; Education examination; Education; Education services; Education information; Educational consultancy; Educational instruction; Educational seminars; Educational research; Training and education services; Education, teaching and training; Dissemination of educational material; Publishing of educational material; Organising of competitions for education; Arranging of educational events; Organisation of educational events; Conducting of educational events; Seminars; Arranging and conducting seminars; Arranging and conducting of lectures; Instructional and training services; Publication and editing of printed matter; Educational research; Teaching; Teaching services; Providing courses of instruction; Cultural activities; Cultural services; Conducting of cultural events; Arranging of cultural events; Education and instruction. Research services; quality assurance consultancy; Providing quality assurance services; Process monitoring for quality assurance; Quality control; Certification [quality control]; Research and development services; Quality control services; Laboratory services. Reviewing standards and practices to assure compliance with laws and regulations; Providing information on issues concerning human rights.
Certain embodiments of the present invention relate to a system and a method for producing a radiopharmaceutical, wherein the system is formed from and/ or provides a microfluidic flow system. In certain embodiments, the system comprises a radioisotope isolation module, a radiopharmaceutical production module, a purification module and a quality control module.
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
38.
METHOD AND APPARATUS FOR THE ANALYSIS OF COMPOUNDS
Embodiments of the present invention relate to microfluidic devices and systems comprising such devices for use in the determination of sample characteristics. Certain embodiments relate to methods for determining one or more characteristics of a sample comprising a compound for in vivo use. Aptly, certain embodiments of the present invention relate to devices and methods for assessing radiopharmaceuticals and their suitability for administration to a patient in need thereof.
The present invention relates to monolithic bodies, uses thereof and processes for the preparation thereof. Certain embodiments of the present invention relate to the use of a monolithic body in the preparation of a radioactive substance, for example a radiopharmaceutical, as part of a microfluidic flow system and a process for the preparation of such a monolithic body.
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
Certain embodiments of the present invention relate to a system and a method for producing a radiopharmaceutical, wherein the system is formed from and/ or provides a microfluidic flow system. In certain embodiments, the system comprises a radioisotope isolation module, a radiopharmaceutical production module, a purification module and a quality control module.
The present invention relates to a method and an apparatus for separating and recovering a radioisotope from a solution. More particularly, certain embodiments of the invention relate to a method for recovering a radioisotope from a solution by electro-trapping and release using a microfluidic cell (10). The radioisotope may subsequently be used in the preparation of radiopharmaceuticals.
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
B01D 57/02 - Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. by electrophoresis
42.
SPEECH SYNTHESIS FROM DETECTED SPEECH ARTICULATOR MOVEMENT
The present invention relates to methods and systems for generating synthesised speech from detected speech articulator movement and to methods and systems for generating models for generating synthesised speech from detected articulator movement.
A method of producing output indicative of the content of speech or mouthed speech from movement of speech articulators is described. The method comprises the following steps. Fixing a plurality of magnets respectively to a plurality of speech articulators of a human individual. Providing a plurality of signal magnetic field sensors located so as to sense a magnetic field intensity component produced by at least one of the magnets and a component produced by the Earth's magnetic field. Providing at least three reference magnetic field sensors able to sense a magnetic field intensity produced at least partially by the Earth's magnetic field. Obtaining, over the period of time, for each said signal magnetic field sensor signal, a respective correction value. Each correction value being indicative of the component that is produced by the Earth's magnetic field and the magnetic field intensity sensed by the corresponding signal magnetic field sensor.
Certain embodiments of the present invention relate to apparatus and methods for providing a target liquid at a desired location. In certain embodiments, the apparatus includes a piercing member locatable with respect to a sealing membrane of a respective blister pouch that has a tip region which is locatable in an abutting relationship with the sealing membrane in a first mode of operation and through the sealing member in a further mode of operation for providing liquid from the blister pouch at a desired location. Also included in the present invention, inter alia, is a piercing plate comprising a piercing member, together with devices, for example, bio chips and microfluidic devices, which are for use in combination with the apparatus.
An apparatus for promoting bone repair, or integration of a prosthesis in a bone, comprises a support (10) securable to a bone (12). A plurality of strain gauges (14a, 14b, 16a, 16b, 18a, 18b, 20a, 20b) are attached to the support (10) at respective different positions of the support (10). The strain gauges (14a, 14b, 16a, 16b, 18a, 18b, 20a, 20b) detect strain on deformation of the support. The apparatus also comprises a controller (22) and a signalling system (24). The signalling system (24) is operatively connected to the strain gauges (14a, 14b, 16a, 16b, 18a, 18b, 20a, 20b) and operatively connected to the controller (22) for providing to the controller (22) signals indicative of respective strains detected by the strain gauges (14a, 14b, 16a, 16b, 18a, 18b, 20a, 20b). The apparatus also comprises a functional electrical stimulation device (36) for applying a functional electrical stimulation to a muscle (56). The controller (22) is operatively connected to the functional electrical stimulation device (36) so that the controller (22) controls the application of functional electrical stimulation dependent on the signals provided by the signalling system (24).
This invention relates to complexes formed by the combination of a metal (M) and various ligands (L). The metals (M) include niobium and tantalum. The complexes serve to catalyze the polymerization of hydrocarbons. The process comprises mixing the complex or a combination of the complexes with a co-catalyst and one or more monomers.
C07F 9/00 - Compounds containing elements of Groups 5 or 15 of the Periodic Table
B01J 31/36 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups of vanadium, niobium or tantalum
A photogalvanic cell comprises a first electrode and a second electrode spaced apart from the first electrode, an aqueous medium arranged between the first and second electrodes and including a lyotropic liquid crystal existing in a structured phase such that the aqueous medium includes at least one surfactant pseudo-phase and at least one aqueous sub-phase, a photoactive first redox couple contained in the surfactant pseudo-phase and a second redox couple contained in the aqueous sub-phase and at least one electrolyte contained in the aqueous sub-phase and, optionally, at least one electrolyte contained in the surfactant pseudo-phase.
H01L 31/06 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof adapted as photovoltaic [PV] conversion devices characterised by at least one potential-jump barrier or surface barrier
B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
The invention provides a method for the chromatographic separation of chemical species, the method comprising the provision of a chromatograph comprising a mesoporous silicon imido nitride (Si2N2(NH)2), silicon diimide (Si(NH)2) mesoporous gel or silicon nitride (Si3N4) mesoporous ceramic stationary phase. Typically, the mesoporous gel is prepared by means of a sol-gel process which is optionally partially or completely pyrolysed to form a mesoporous silicon imido nitride or silicon nitride mesoporous ceramic. The chromatographic separation method generally comprises liquid phase column chromatography or gas chromatography and is particularly applied to the separation of acid-sensitive organic molecules which may include proteins or compounds used in the preparation of pharmaceuticals, and the removal of catalytic amounts of metal ions from reaction products. The invention also provides a chromatograph comprising the disclosed stationary phase and envisages the preparation of a chromatograph by incorporating this stationary phase in a chromatographic column.
C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon
G01N 30/90 - Plate chromatography, e.g. thin layer or paper chromatography
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
The invention provides a photopolymerisable or photocrosslinkable reactive mesogen for forming a charge transporting or light emitting polymer network, the mesogen having an asymmetric structure (II): B1-S1-A1-M-(A-S-B)n (II) wherein: A and A1 are chromophores; S and S1 are spacers; B and B1 are endgroups which are susceptible to photopolymerisation or photocrosslinking; M is a non-chromophoric aliphatic, alicyclic or aromatic moiety; and n is an integer from 1 to 3; wherein, when the value of n is greater than 1, each of the groups A, S and B may be the same or different. Preferably, M is of the formula Y-Zm, wherein Y is an aliphatic, alicyclic, aromatic or heterocyclic moiety, Z is an aliphatic linking group and m is an integer from 2 to 4, and wherein each of the Z groups may be the same or different. The invention also provides a material for forming a light emitting or charge transporting polymer network comprising the photopolymerisable or photocrosslinkable reactive mesogen, a charge transporting or light emitting polymer network which is obtained by polymerisation or crosslinking of the mesogen, a process for the preparation of the polymer via photopolymerisation or photocrosslinking of suitable end-groups of the mesogen, a device comprising a polymer layer formed from the charge transporting or light emitting polymer network, a process for applying a charge transporting or light emitting polymer network to a surface and a backlight or display comprising a charge transporting or light emitting polymernetwork.
C09K 19/34 - Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
H05B 33/14 - Light sources with substantially two-dimensional radiating surfaces characterised by the chemical or physical composition or the arrangement of the electroluminescent material
50.
METHODS AND APPARATUS FOR AMPLIFYING NUCLEIC ACIDS
A method of amplifying nucleic acid comprises providing a microfluidic device (10) having a space therein (32). The space (32) is filled with a gel medium (54). Reagents for carrying out a PCR reaction are supported within the matrix of the gel medium (54) within the space (32). A nucleic acid containing sample is brought into contact with the gel medium (54). The sample comprises whole cells or cell lysate without any prior separation of the nucleic acid from other components of the cells. PCR amplification of nucleic acid from the sample is performed in the space using the PCR reagents.
A tool (106) for facilitating insertion of a speech valve (10) with a flexible retention flange (56) into a fistula between the trachea and the oesophagus of a human patient, having a wall (108) curved to define a passage (116) having opposed open first and second passage ends and an axis extending therebetween, said wall (108) having an external surface (118) insertable into a fistula between the said trachea and oesophagus and defining a slot (110) which extends from the passage (116) to the external surface (118) of the wall (108), said slot (110) having an opening at the first passage end extending from the first passage end to at least a part of the way to the second passage end and at least a portion of the said slot (110) progresses angularly around the said axis as it progresses from the first passage end towards the second passage end.
The present invention refers of feed additives for aquaculture and aquarium culture. These additives comprise the amino acid, 1-methyl-L-tryptophan, or its isomers with the objective of improving the attractiveness of feeds used in aquaculture and aquaria for fish, as well as other aquatic organisms, under culture conditions. Therefore, this invention has applications in the agriculture-food industry.
A condenser for collecting breath condensate comprises a vessel for holding a condensing medium and a conduit having an inlet at a first end and an exhaust at a second end, in which the first and second ends are outside of the vessel. A collection port is provided outside of the vessel and in fluid communication with the conduit for collecting condensate. A portion of the conduit is housed within the vessel and positioned so as to be submerged in the condensing medium when the condenser is in use and further arranged so that condensate which forms within the conduit can flow along the conduit under gravity to the collection port when the condenser is in use. The vessel has a base which can sit on a support surface such as a table when the condenser is in use.
The invention provides a method of forming a photonic crystal structure by means of a polymerisable material comprising the steps of: forming a layer of the polymerisable material, the polymerisable material being arranged to experience photoinduced mass transfer upon irradiation with optical radiation; and exposing the polymerisable material to said optical radiation at locations corresponding to a photonic crystal structure to be patterned thereby to form said structure by photoinduced mass transfer.
The present invention is concerned with the immobilization of enzymes and their co-factors in a system which permits regeneration of the co-factors. Also included in the present invention are methods and devices which utilize such systems.
C12N 11/14 - Enzymes or microbial cells immobilised on or in an inorganic carrier
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
A device for disintegrating a tablet, the device comprising a receptacle configured to receive a tablet and a sonication means for generating ultrasonic waves, wherein the sonication means is adapted to sonicate the tablet at a frequency suitable to effect resonance of the tablet to effect disintegration of said tablet. A method for disintegrating a tablet is also provided.
The present disclosure relates to the treatment of inflammatory disorders. In particular, although not exclusively the present disclosure relates to agents which inhibit a Mas related gene (Mrg) receptor for use in the treatment or prevention of a disorder associated with inflammation. Also included in the present disclosure are methods of treatment, assays and other subject matter.
A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 25/00 - Drugs for disorders of the nervous system
58.
MICROFLUIDIC APPARATUS AND METHOD FOR DNA EXTRACTION, AMPLIFICATION AND ANALYSIS
An integrated gel based microfluidic sample processing device An integrated gel based microfluidic sample processing device, suitable for forensic investigations at the scene of a crime,comprising a substrate having a plurality of micro-channels to form at least a DNA extraction chamber in fluidic cooperation with an amplification chamber which in turn is in fluidic cooperation with a separation and detection channel; said micro-channels containing a DNA extraction material and gel based reaction reagents necessary for processing said sample; the device further comprising electrical contacts for coupling to an external power source and capable of inducing electro-kinetic manipulation of said gel based reagents and DNA extracted from said sample throughout the device.
A whitened exine shell having a degree of whiteness (L*) of greater than 65 measured under D 65 illumination. The shell can be used as a delivery vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy or diagnosis. The invention provides a formulation containing the whitened exine shell together with an active substance; and a method for preparing the shell by isolating an exine shell from a naturally occurring spore under treatment conditions which do not include aceto lysis, and treating the isolated shell or a precursor thereof with a bleaching composition.
A61K 35/66 - Microorganisms or materials therefrom
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 35/66 - Microorganisms or materials therefrom
61.
METHOD OF OPERATING A FLUIDIC DEVICE AND A FLUIDIC DEVICE FOR USE IN THE METHOD
A method comprises introducing a fluid carrying mobile elements, such as particles (24), into a fluidic device. Simultaneously a mobile element receiving fluid and one or more further fluids are also introduced into the fluidic device. The fluids are passed through a chamber (12) in respective, parallel fluid streams (32, 34, 36, 38, 40). The fluid streams are arranged such that each fluid stream contacts at least another one of the fluid streams in the chamber (12). The dimensions of the chamber are such that the fluid streams undergo laminar flow and remain generally distinct from one another. A force is applied to the mobile elements (24) which causes the mobile elements to leave the fluid stream (32) of the mobile element carrying fluid, pass through the fluid stream(s) (34, 36, 38) of the further fluid(s) and enter into the fluid stream (40) of the mobile element receiving fluid. As the mobile elements pass through the fluid streams reactions can take place between species bound to the mobile elements and species carried in the fluid streams.
A speech valve (10) comprises a generally cylindrical body (12, 14, 16) and a closure member (62) which is slidably movable within the body (12, 14, 16) between a closed position and an open position. The valve body and the closure member (62) are formed of a rigid, smooth material which is resistant to the growth of biofilm, such as a ceramic. A particular suitable ceramic is partially stabilised zirconia. The valve body is provided with an outer sleeve (76) which is provided with radially outwardly extending annular flanges (82, 86), which are used to retain the speech valve in a fistula between the oesophagus and the trachea.
The present disclosure relates to catheters, for example a catheter which is adapted such that the user is able to determine whether it has been correctly positioned within 5 the subject. Also included in the present disclosure are means for detecting the position of the catheter and combinations of a catheter and processors for determining the positioning of the catheter. The present disclosure also relates to methods of determining the position of a catheter in, for example, a human or animal body.
The invention provides a cancer screening test, to identify patients having an increased likelihood of cancer, comprising the step of determining the presence or absence of members of a test group of tumour associated antigens in the blood of a patient. The test group comprises a plurality of tumour-associated antigens. Antigens of particular interest include Vascular Endothelial Growth Factor-A (VEGF A); CEA125 (Carcinoembryonic antigen 125); Prostate Specific Antigen (PSA); CA15-3 (Cancer antigen 15-3); CA125 (Cancer Antigen 125); CYFRA21-1 (Cytokeratin-19 fragments); Soluble ectodomain of c- erbB2; CA27.29 (Cancer Antigen 27.29); IGF-I (Insulin-like growth factor-1); IGF-2 (Insulin-like growth factor-2); and IGFBP-3 (Insulin-like growth factor binding protein 3). The invention also provides an antibody-based test kit to implement the screening method.
The invention relates to pharmaceutically useful agents that antagonize the activity of a calcium ion channel receptor and their use in the inhibition of receptor activation in the treatment of conditions that would benefit from said inhibition; and including screening assays to identify antagonists of receptor activation and other subject matter. The agent may be a pheniramine.
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non- living surface. The invention may be used to provide gradual release of the active substance over a period of time subsequent to application of the formulation to the surface.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
The invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance or composition, by encapsulating the substance or composition in, or chemically or physically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
The invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance or composition, by encapsulating the substance or composition in, or chemically or physically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A compound of Formulae (1), (2) or (3), A1-Ph (1) or A1-Ar-A2 (2) or A1-(A2)A~- A3 (3) wherein A1, A2 and A3 are selected from Formulae (4), (5) and (6), or a salt whereof; wherein Ar is selected from the group consisting of 1,2-phenyl, 1,3-phenyl and 1,4-phenyl optionally substituted with one or more methyl groups; m and n are independently integers from 0 to l; Ph is phenyl, optionally substituted with one or more methyl groups; Arl is trisubstituted phenyl optionally substituted with one or more phenyl groups; and R1, R2 and R3 are independently selected from the group consisting of H, Me and linear chain C2- C4 alkyl.
A pharmaceutical or dietetic dosage form comprising of effective quantity of an active substance chemically or physically bound to a support comprising, sporopollenin, or other similar exine coating of spores, of a plant of fungus, optionally with further excipients.
