A method of a bridge network device manager can include performing a first query on a device of a network of operational technology devices; gathering first feature information of the device based on the first query; generating a first instance of a device record that includes the first feature information; selecting a second query based on the first instance of the device record, the second query selected from a query set for features of operational technology devices operating in a particular physical domain; performing the second query on the device; gathering second feature information of the device based on the second query; updating the device record based on the second feature information to generate an updated device record; and predicting a type of the device based on the updated device record. Additional queries can be performed to predict the device record.
A method of a bridge network device manager can include performing a first query on a device of a network of operational technology devices; gathering first feature information of the device based on the first query; generating a first instance of a device record that includes the first feature information; selecting a second query based on the first instance of the device record, the second query selected from a query set for features of operational technology devices operating in a particular physical domain; performing the second query on the device; gathering second feature information of the device based on the second query; updating the device record based on the second feature information to generate an updated device record; and predicting a type of the device based on the updated device record. Additional queries can be performed to predict the device record.
H04L 41/08 - Configuration management of networks or network elements
H04L 41/12 - Discovery or management of network topologies
H04L 41/16 - Arrangements for maintenance, administration or management of data switching networks, e.g. of packet switching networks using machine learning or artificial intelligence
A wave energy converter is provided and comprises a vessel configured for alternative expansion and contraction. The vessel comprises two rigid panels configured for relative movement with respect to each other, and one or more pleated portions provided between the panels, in which the or each pleated portion has a polyhedral structure.
F03B 13/18 - Adaptations of machines or engines for special useCombinations of machines or engines with driving or driven apparatusPower stations or aggregates characterised by using wave or tide energy using wave energy using the relative movement between a wave-operated member and another member wherein the other member is fixed, at least at one point, with respect to the sea bed or shore
F03B 13/20 - Adaptations of machines or engines for special useCombinations of machines or engines with driving or driven apparatusPower stations or aggregates characterised by using wave or tide energy using wave energy using the relative movement between a wave-operated member and another member wherein both members are movable relative to the sea bed or shore
4.
Method for the Generation of Non-Transformed Macrophage Cell Line
A method for producing continuously replicating, non-transformed pig macrophages, comprising culturing a cell preparation from an organ obtained from a pig in culture medium to which GM-CSF has been added thereby differentiating the cell population into self-renewing, non-transformed macrophages.
A wave energy converter is provided and comprises a pneumatic vessel configured for alternate expansion and contraction and in use drawing air in and expelling it. The pneumatic vessel includes an inner bellows arrangement and an outer bellows arrangement. The vessel further includes a plurality of dividers. The inner bellows are configured to prevent buckling of the dividers; and the dividers are configured to prevent buckling of the inner bellows.
F03B 13/18 - Adaptations of machines or engines for special useCombinations of machines or engines with driving or driven apparatusPower stations or aggregates characterised by using wave or tide energy using wave energy using the relative movement between a wave-operated member and another member wherein the other member is fixed, at least at one point, with respect to the sea bed or shore
6.
KINASE INHIBITORS FOR USE IN TREATING ALEXANDER DISEASE
Alexander disease is a rare disorder of the nervous system. The present invention is based on the observation that Alexander disease is associated with changes in phosphorylation status of glial fibrillary acidic protein around mutation sites. A method for the discovery of kinase inhibitors that can be used for individual patients with Alexander disease Is provided and kinase inhibitor for the treatment of Alexander disease are provided.
A61K 31/00 - Medicinal preparations containing organic active ingredients
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
09 - Scientific and electric apparatus and instruments
16 - Paper, cardboard and goods made from these materials
28 - Games; toys; sports equipment
Goods & Services
Audiovisual, teaching, instructional and educational software, apparatus and instruments; recorded and downloadable media; computer programs; computer software, computer applications; smartphone apps; tablet applications; educational tablet applications; mobile apps; educational mobile apps; computer games; game software; interactive education software; educational software in the fields of medicine, physiology, healthcare and science; downloadable educational publications and materials; digital educational materials. Printed matter; instructional and teaching materials; cards; flashcards; educational cards; reference cards; printed cards; printed informational cards; printed educational cards; printed informational material; printed educational material; printed informational cards in the fields of medicine, physiology, healthcare and science; printed educational cards in the fields of medicine, physiology, healthcare and science; printed informational material in the fields of medicine, physiology, healthcare and science; printed educational material in the fields of medicine, physiology, healthcare and science. Games; card games; playing cards; educational card games; game cards; educational card games in the fields of medicine, physiology, healthcare and science; electronic games; electronic game apparatus.
An isolated or recombinant polypeptide is provided and comprises a sequence selected from the group comprising NI01, α1α2, α2α3, α3α4, α1α2α3, α2 α3 α4, R-NI01, NT-205, H16, H1M NI01-R, 3NH (α1α3α3), H1 (α1α2), H2 (α2α3), 3HC (α2α3α4) or having at least 75% identity thereto, wherein the isolated or recombinant polypeptide is bactericidal and/or bacteriostatic.
A method for producing continuously replicating, non-transformed pig macrophages, comprising culturing a cell preparation from an organ obtained from a pig in culture medium to which GM-CSF has been added thereby differentiating the cell population into self-renewing, non-transformed macrophages.
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
39 - Transport, packaging, storage and travel services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable computer software for risk assessment, risk
detection, risk detection, risk prevention and risk
management; downloadable computer software for risk
assessment, risk detection, risk prevention and risk
management in relation to cyberattack, ransomware attack,
hacking and cyberterrorism; downloadable computer software
for risk assessment, risk detection, risk prevention and
risk management in relation to cyberattack, ransomware
attack, hacking and cyberterrorism on means of transport;
downloadable computer software for risk assessment, risk
detection, risk prevention and risk management in relation
to cyberattack, ransomware attack, hacking and
cyberterrorism on vehicles and apparatus for locomotion by
land, air or water; downloadable computer software for risk
assessment, risk detection, risk prevention and risk
management in relation to cyberattack, ransomware attack,
hacking and cyberterrorism on maritime craft, water craft,
air craft and land vehicles. Business risk assessment, risk detection, risk prevention
and risk management services; business consultancy
information and advisory services in relation to risk
assessment, risk detection, risk prevention and risk
management related to cyberattack, ransomware attack,
hacking and cyberterrorism; business risk management
consultancy in relation to cyberattack, ransomware attack,
hacking and cyberterrorism; consultancy, information and
advisory services in relation to all the aforementioned. Risk assessment, risk detection, risk prevention and risk
management services in relation to means of transport; risk
assessment, risk detection, risk prevention and risk
management services in relation to cyberattack, ransomware
attack, hacking and cyberterrorism on means of transport;
risk assessment, risk detection, risk prevention and risk
management services in relation to cyberattack, ransomware
attack, hacking and cyberterrorism on vehicles and apparatus
for locomotion by land, air or water; risk assessment, risk
detection, risk prevention and risk management services in
relation to cyberattack, ransomware attack, hacking and
cyberterrorism on maritime craft, water craft, air craft and
land vehicles; consultancy, information and advisory
services in relation to all the aforementioned; consultancy,
information and advisory services in relation to transport;
maritime consultancy, information and advisory services. Education and training services; education and training
services in relation to cyberattack, ransomware attack,
hacking and cyberterrorism; education and training services
in relation to risk assessment, risk detection, risk
prevention and risk management; education and training
services in relation to risk assessment, risk detection,
risk prevention and risk management related to cyberattack,
ransomware attack, hacking and cyberterrorism; consultancy,
information and advisory services in relation to all the
aforementioned. Research & development in relation to cyberattack,
ransomware attack, hacking and cyberterrorism; research & development in relation to assessment, detection, prevention
and management of risks related to cyberattack, ransomware
attack, hacking and cyberterrorism; research, design,
development, provision, installation, maintenance & updating
of computer software; research, design, development,
provision, installation, maintenance & updating of computer
software for assessment, prevention and management of risks
related to cyberattack, ransomware attack, hacking and
cyberterrorism; software as a service (SaaS); hosting
services; providing online non-downloadable software;
consultancy, information and advisory services in relation
to all the aforementioned.
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
39 - Transport, packaging, storage and travel services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable computer software for risk assessment, risk
detection, risk detection, risk prevention and risk
management; downloadable computer software for risk
assessment, risk detection, risk prevention and risk
management in relation to cyberattack, ransomware attack,
hacking and cyberterrorism; downloadable computer software
for risk assessment, risk detection, risk prevention and
risk management in relation to cyberattack, ransomware
attack, hacking and cyberterrorism on means of transport;
downloadable computer software for risk assessment, risk
detection, risk prevention and risk management in relation
to cyberattack, ransomware attack, hacking and
cyberterrorism on vehicles and apparatus for locomotion by
land, air or water; downloadable computer software for risk
assessment, risk detection, risk prevention and risk
management in relation to cyberattack, ransomware attack,
hacking and cyberterrorism on maritime craft, water craft,
air craft and land vehicles. Business risk assessment, risk detection, risk prevention
and risk management services; business consultancy
information and advisory services in relation to risk
assessment, risk detection, risk prevention and risk
management related to cyberattack, ransomware attack,
hacking and cyberterrorism; business risk management
consultancy in relation to cyberattack, ransomware attack,
hacking and cyberterrorism; consultancy, information and
advisory services in relation to all the aforementioned. Risk assessment, risk detection, risk prevention and risk
management services in the nature of transportation
logistics in relation to means of transport; consultancy,
information and advisory services in relation to all the
aforementioned; consultancy, information and advisory
services in relation to transport; maritime transport
consultancy, information and advisory services. Education and training services; education and training
services in relation to cyberattack, ransomware attack,
hacking and cyberterrorism; education and training services
in relation to risk assessment, risk detection, risk
prevention and risk management; education and training
services in relation to risk assessment, risk detection,
risk prevention and risk management related to cyberattack,
ransomware attack, hacking and cyberterrorism; consultancy,
information and advisory services in relation to all the
aforementioned. Research & development in relation to cyberattack,
ransomware attack, hacking and cyberterrorism; research & development in relation to assessment, detection, prevention
and management of risks related to cyberattack, ransomware
attack, hacking and cyberterrorism; research, design,
development, installation, maintenance and updating of
computer software; provision of online non-downloadable
computer software; research, design, development,
installation, maintenance and updating of computer software
for assessment, prevention and management of risks related
to cyberattack, ransomware attack, hacking and
cyberterrorism; provision of online non-downloadable
computer software for assessment, prevention and management
of risks related to cyberattack, ransomware attack, hacking
and cyberterrorism; software as a service (SaaS); hosting of
software as a service [SaaS]; providing online
non-downloadable software; consultancy, information and
advisory services in relation to all the aforementioned;
risk assessment, risk detection, risk prevention and risk
management services in relation to cyberattack, ransomware
attack, hacking and cyberterrorism on means of transport;
risk assessment, risk detection, risk prevention and risk
management services in relation to cyberattack, ransomware
attack, hacking and cyberterrorism on vehicles and apparatus
for locomotion by land, air or water; risk assessment, risk
detection, risk prevention and risk management services in
relation to cyberattack, ransomware attack, hacking and
cyberterrorism on maritime craft, water craft, air craft and
land vehicles.
12.
METHOD AND SYSTEM FOR DYNAMICALLY ASSESSING CURRENT RISK ASSOCIATED WITH A MARITIME ACTIVITY
An approach is provided for a maritime cyber risk assessment profiling tool. The tool accesses a risk profile for one or more maritime vessels, wherein the risk profile includes a plurality of attack vectors targeting a plurality of systems associated with the one or more maritime vessels, and wherein each of the plurality of attack vectors is associated with a quantified risk value. The tool retrieves a risk update from a dynamic risk data source. The tool updates the risk profile based on the risk update, including a first attack vector. The tool causes display of a risk assessment for the one or more maritime vessels based on the updated risk profile, wherein the risk assessment includes risk values assigned for a particular set of the plurality of systems including a risk value that changed based on the update to the first attack vector.
G06F 21/57 - Certifying or maintaining trusted computer platforms, e.g. secure boots or power-downs, version controls, system software checks, secure updates or assessing vulnerabilities
13.
METHOD AND SYSTEM FOR DYNAMICALLY ASSESSING CURRENT RISK ASSOCIATED WITH A MARITIME ACTIVITY
An approach is provided for a maritime cyber risk assessment profiling tool. The tool accesses a risk profile for one or more maritime vessels, wherein the risk profile includes a plurality of attack vectors targeting a plurality of systems associated with the one or more maritime vessels, and wherein each of the plurality of attack vectors is associated with a quantified risk value. The tool retrieves a risk update from a dynamic risk data source. The tool updates the risk profile based on the risk update, including a first attack vector. The tool causes display of a risk assessment for the one or more maritime vessels based on the updated risk profile, wherein the risk assessment includes risk values assigned for a particular set of the plurality of systems including a risk value that changed based on the update to the first attack vector.
G06F 21/57 - Certifying or maintaining trusted computer platforms, e.g. secure boots or power-downs, version controls, system software checks, secure updates or assessing vulnerabilities
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
39 - Transport, packaging, storage and travel services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable computer software for risk assessment, risk detection, risk detection, risk prevention and risk management; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on vehicles and apparatus for locomotion by land, air or water; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles Business risk assessment, risk detection, risk prevention and risk management services; business consultancy information and advisory services in relation to risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism; business risk management consultancy in relation to cyberattack, ransomware attack, hacking and cyberterrorism; consultancy, information and advisory services in relation to all the aforementioned Risk assessment, risk detection, risk prevention and risk management services in relation to means of transport, namely transportation consulting in relation to risk assessment and risk detection relating to maritime transportation, providing transportation information in relation to risk assessment and risk detection relating to maritime transportation and transportation advice in relation to risk assessment and risk detection relating to maritime transportation; consultancy, information and advisory services in relation to transport; transportation consulting, namely maritime consultancy, information and advisory services Training services, namely, training in the field of cyberattack, ransomware attack, hacking and cyberterrorism; training services, namely, training in the field of risk assessment, risk detection, risk prevention and risk management; training services, namely, training in the field of risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism; consultancy, information and advisory services in relation to all the aforementioned Research and development in relation to cyberattack, ransomware attack, hacking and cyberterrorism; research and development in relation to assessment, detection, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism; research, design, development, provision, installation, maintenance and updating of computer software; research, design, development, provision, installation, maintenance and updating of computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport; software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; hosting of software as a service, featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; hosting of software as a service featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; providing online non-downloadable software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; providing online non-downloadable software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport; providing online non-downloadable software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; consultancy, information and advisory services in relation to all the aforementioned
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
39 - Transport, packaging, storage and travel services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Downloadable computer software for use in assessing, detecting, preventing and managing cybersecurity risk; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism in the field of transportation; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on vehicles and apparatus for locomotion by land, air or water; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles (1) Business risk assessment, business risk detection, business risk prevention and business risk management services and consultancy information and advisory services in relation thereto; business consultancy information and advisory services in relation to risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism; business risk management consultancy in relation to cyberattack, ransomware attack, hacking and cyberterrorism
(2) Risk assessment, risk detection, risk prevention and risk management services in the field of marine transport, namely consulting in relation to the assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on marine transport, providing information in relation to the risk of cyberattack, ransomware attack, hacking and cyberterrorism on marine transport, advising in relation to assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on marine transport; risk assessment, risk detection, risk prevention and risk management services in the field of cyberattack, ransomware attack, hacking and cyberterrorism in the field of transport, namely consulting in relation to the assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on transportation, providing information in relation to the risk of cyberattack, ransomware attack, hacking and cyberterrorism on transportation, advising in relation to assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on transportation; risk assessment, risk detection, risk prevention and risk management services in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles, namely consulting in relation to the assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles, providing information in relation to the risk of cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles, advising in relation to assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles; consultancy, information and advisory services in the field of marine transport and freight transportation by truck, rail, air and ocean
(3) Arranging and providing education and training in the field of risk management, and consultancy, information and advisory services in relation thereto; arranging and providing education and training in the field of the assessment, analysis, detection, prevention, mitigation, management and resolution of cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; arranging and providing education and training in the field of risk assessment, risk detection, risk prevention and risk management in the field of transportation, and consultancy, information and advisory services in relation thereto; education and training services in relation to risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto
(4) Research & development in the field of cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles, and consultancy, information and advisory services in relation thereto; research & development in relation to assessment, detection, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles, in the fields of project management, diagnostic services, data security, technical research and analysis, and technological planning, and consultancy, information and advisory services in relation thereto; research, design, development, provision, installation, maintenance & updating of computer software for assessment, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; software as a service (SaaS) featuring computer software for use in the assessment, prevention, detection, analysis, mitigation, management and resolution of risk and threats in the field of cybersecurity, and consultancy, information and advisory services in relation thereto; hosting of software as a service [SaaS] in the field of the assessment, analysis, detection, prevention, mitigation, management and resolution of threats in the field of cybersecurity risk, and consultancy, information and advisory services in relation thereto; providing online non-downloadable software in the field of the assessment, analysis, detection, prevention, mitigation, management and resolution of threats in the field of cybersecurity risk and consultancy, information and advisory services in relation thereto
Methods for the diagnosis of meningioma in a subject are described, comprising in vitro determining whether messenger RNA sequences miR-9-1 or MiR-497 have increased levels in a sample of the subject when compared to a sample obtained from a healthy individual and/or between benign and higher-grade meningioma tumors.
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
39 - Transport, packaging, storage and travel services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable computer software for risk assessment, risk detection, risk detection, risk prevention and risk management; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on vehicles and apparatus for locomotion by land, air or water; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles Business risk assessment, business risk detection, business risk prevention and business risk management services; business consultancy information and advisory services in relation to business risk assessment, business risk detection, business risk prevention and business risk management related to cyberattack, ransomware attack, hacking and cyberterrorism; business risk management consultancy in relation to cyberattack, ransomware attack, hacking and cyberterrorism; consultancy, information and advisory services in relation to all the aforementioned Risk assessment, risk detection, risk prevention and risk management services in the nature of transportation logistics in relation to means of transport, namely consulting in relation to the risk assessment, risk detection, risk prevention and risk management of cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport, providing information in relation to the risk assessment, risk detection, risk prevention and risk management of cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport and advising in relation to risk assessment, risk detection, risk prevention and risk management of cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; consultancy, information and advisory services in relation to transport; maritime transport consultancy, information and advisory services Training services, namely, training in the field of cyberattack, ransomware attack, hacking and cyberterrorism; training services, namely, training in the field of risk assessment, risk detection, risk prevention and risk management; training services, namely, training in the field of risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism; consultancy, information and advisory services in relation to all the aforementioned Research and development in relation to cyberattack, ransomware attack, hacking and cyberterrorism; research and development in relation to assessment, detection, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism; research, design, development, installation, maintenance and updating of computer software; provision of online non-downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; providing temporary use of non-downloadablecomputer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport;providing temporary use of non-downloadablecomputer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; research, design, development, installation, maintenance and updating of computer software for assessment, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism; provision of online non-downloadable computer software for assessment, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism; software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport; software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; hosting of software as a service (SaaS) featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; hosting of software as a service featuring software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; providing online non-downloadable software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; providing online non-downloadable software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport; providing online non-downloadable software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime transport; consultancy, information and advisory services in relation to all the aforementioned; risk assessment, risk detection, risk prevention and risk management services in the nature of technical research and technological planning and consulting in the field of risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on means of transport and consultancy, information and advisory services in relation thereto; risk assessment, risk detection, risk prevention and risk management services in the nature of technical research and technological planning and consulting in the field of risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on vehicles and apparatus for locomotion by land, air or water and consultancy, information and advisory services in relation thereto; risk assessment, risk detection, risk prevention and risk management services in the nature of technical research and technological planning and consulting in the field of risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles and consultancy, information and advisory services in relation thereto
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
39 - Transport, packaging, storage and travel services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Downloadable computer software for use in assessing, detecting, preventing and managing cybersecurity risk; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism in the field of transportation; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on vehicles and apparatus for locomotion by land, air or water; downloadable computer software for risk assessment, risk detection, risk prevention and risk management in relation to cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles (1) Business risk assessment, business risk detection, business risk prevention and business risk management services and consultancy information and advisory services in relation thereto; business consultancy information and advisory services in relation to risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism; business risk management consultancy in relation to cyberattack, ransomware attack, hacking and cyberterrorism
(2) Risk assessment, risk detection, risk prevention and risk management services in the nature of transportation logistics in in the field of marine transport, namely consulting in relation to the assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on marine transport, providing information in relation to the risk of cyberattack, ransomware attack, hacking and cyberterrorism on marine transport, advising in relation to assessment, analysis, detection, prevention, mitigation, management and resolution of the risk of cyberattack, ransomware attack, hacking and cyberterrorism on marine transport; consultancy, information and advisory services in the field of marine transport and freight transportation by truck, rail, air and ocean
(3) Arranging and providing education and training in the field of risk management, and consultancy, information and advisory services in relation thereto; arranging and providing education and training in the field of the assessment, analysis, detection, prevention, mitigation, management and resolution of cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; arranging and providing education and training in the field of risk assessment, risk detection, risk prevention and risk management in the field of transportation, and consultancy, information and advisory services in relation thereto; education and training services in relation to risk assessment, risk detection, risk prevention and risk management related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto
(4) Research & development in to the field of transportation related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; research & development in relation to assessment, detection, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; research, design, development, installation, maintenance and updating of computer software for assessment, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism in the field of transportation, and consultancy, information and advisory services in relation thereto; provision of online non-downloadable computer software for use in the assessment, analysis, detection, prevention, mitigation, management and resolution of risk and threats in the field of cybersecurity, and consultancy, information and advisory services in relation thereto; research, design, development, installation, maintenance and updating of computer software for assessment, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; provision of online non-downloadable computer software for assessment, prevention and management of risks related to cyberattack, ransomware attack, hacking and cyberterrorism, and consultancy, information and advisory services in relation thereto; software as a service (SaaS) featuring computer software for use in the assessment, prevention, detection, analysis, mitigation, management and resolution of risk and threats in the field of cybersecurity, and consultancy, information and advisory services in relation thereto; hosting of software as a service [SaaS] in the field of the assessment, analysis, detection, prevention, mitigation, management and resolution of threats in the field of cybersecurity risk and consultancy, information and advisory services in relation thereto; risk assessment, risk detection, risk prevention and risk management services in the nature of project management, diagnostic services, data security services, technical research and analysis, and technological planning, support and consulting in the field of cyberattack, ransomware attack, hacking and cyberterrorism in the field of transportation; risk assessment, risk detection, risk prevention and risk management services in the nature of project management, diagnostic services, data security services, technical research and technological planning, support and consulting in the field of cyberattack, ransomware attack, hacking and cyberterrorism on vehicles and apparatus for locomotion by land, air or water; risk assessment, risk detection, risk prevention and risk management services in the nature of project management, diagnostic services, data security services, technical research and technological planning, support and consulting in the field of cyberattack, ransomware attack, hacking and cyberterrorism on maritime craft, water craft, air craft and land vehicles
A control arrangement is described which comprises an inductor (16) of small inductance and having an input side and an output side, the input side being connected to an input line (18) connected, in use, to an output from a power supply (12), and the output side being connected to an output line (20) connected, in use, to a load (14), and a switched capacitor arrangement (22) located to the input side of the inductor (16), the switched capacitor arrangement (22) being arranged such that an average voltage on the input line is maintained above a predetermined level during use of the control arrangement.
H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load
H02M 3/07 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using resistors or capacitors, e.g. potential divider using capacitors charged and discharged alternately by semiconductor devices with control electrode
An isolated or recombinant polypeptide is provided and comprises a sequence selected from the group comprising NI01, α1α2, α2α3, α3α4, α1α2α3, α2 α3 α4, R-NI01, NT-205, H16, H1M NI01-R, 3NH (α1α3α3), H1 (α1α2), H2 (α2α3), 3HC (α2α3α4) or having at least 75% identity thereto, wherein the isolated or recombinant polypeptide is bactericidal and/or bacteriostatic.
In general terms, the present invention provides a storage system for a fruit or vegetable picking system, in which picked fruit or vegetables are delivered to a fixed filling location of the storage system, and then moved, by a robotic handling mechanism of the storage system, to one of many container locations where filled containers (punnets) are temporarily stored.
In general terms a first aspect of the invention provides a modular robotic arm in which respective joint modules and/or end effector modules can be swapped or exchanged for a replacement module. The modules are interconnected by pairs of interlocking features that can be readily and repeatably interlocked and separated.
Described is a composition for protecting against demyelination and other forms of myelin injury, comprising a combination of an NDMA-type glutamate receptor antagonist and a non-NMDA-type glutamate receptor antagonist.
A61K 31/4422 - 1,4-Dihydropyridines, e.g. nifedipine, nicardipine
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
An optometry device is described comprising a projection device (12a, 12b) whereby a target image can be projected onto a tear film on a patient's eye, the projection device (12a, 12b) being of hollow tubular form and so defining a passage through which a patient can view a viewing location (28) and through which imaging of the patient's eye can be undertaken, a recording device (22a, 22b) operable to record an image of the patient's eye onto which the target image has been projected, and a partially reflective beam splitter (26a, 26b) located optically between the patient's eye and the recording device (22a, 22b), and between the patient's eye and the viewing location (28).
In general terms, the present invention provides a passively compliant robotic arm having one or more variable stiffness joints controllable by first and second bi-directional actuators that can be independently operated. Each bi-directional actuator may be operable in a first configuration to urge the joint in a first direction, and in a second configuration to urge the joint in a second direction opposite to the first direction. The bi-directional actuators may be operated in a cooperating mode (high torque mode) in which they work in tandem (i.e. both in the first configuration or second configuration) to double the available torque output. The bi-directional actuators may also (or alternatively) be operated in a high stiffness mode (antagonist mode) in which they counter-act each other by operating so that they oppose one another (i.e. one in the first configuration and the other in the second configuration). The high torque mode may be utilised for an initial portion of a movement trajectory, and the antagonist mode for a final portion of the movement trajectory. The relatively high stiffness in the high stiffness/antagonist mode results from the combined effects of the non-linear force-deflection relationship of the first and second resilient members. The resilient members may each comprise an elastic element, tendon or other resilient member that can be stretched (elongated) to increase tension therein and thereby urge the joint to move.
A cell culture plate stimulator system for measuring bioenergetic behaviour of muscle cells is provided. The system comprises a plate having one or more wells in which muscle cells can be grown, and means for applying, in use, a pulsed electrical field to the cells to stimulate their contraction in use. The means for applying the pulsed electrical field comprise one or more H-bridge circuits.
in situin situ is provided.The meter comprises:an LED for generating a first wavelength in the range of about 670nm to 680nm; an LED for generating a second wavelength in the range of about 685nm to 695nm;a sample chamber for receiving a liquid sample;a sample detector for detecting light at the first and second wavelengths after it is transmitted through a sample; and means for determining light transmittance at the first and second wavelengths.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/84 - Systems specially adapted for particular applications
29.
THE EFFECT OF MANDELATE AND LACTATE ON SPORE GERMINATION
sensulatolato, comprising the step of administering to a bacterial population a germinant comprising:inosine; one or more amino acids; andmandelate and/or lactate.
A62D 3/02 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by biological methods, i.e. processes using enzymes or microorganisms
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
There is provided a non-PCR based method for construction of a DNA recombination fragment with necessary flanking regions homologous to a desired site of genetic manipulation within a target DNA required for recombination-based manipulation of said target DNA, comprising the steps of: A) identifying a desired site of insertion for a genetic element in said target DNA; B) locating an endogenous, native, half-site of a selected restriction endonuclease present upstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 5′ extent of an upstream homology region; C) locating an endogenous, native, half-site of the same selected restriction endonuclease present downstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 3′ extent of a downstream homology region; D) synthesising a flanking region cassette resulting in juxtapositioning of the upstream and downstream half-sites thereby causing formation of complete restriction site for the selected restriction endonuclease flanked by said upstream and downstream homology regions; and E) inserting the flanking region cassette into a plasmid vector which includes the genetic element to be used to manipulate the target DNA, conferring upon the plasmid vector the necessary flanking homology regions for recombination within the said target DNA at the desired site of insertion.
An original electronic file (22) is processed with a biometric feature vector file corresponding to an individual to produce a series of digital imprint files stored in storage (20). A given digital imprint file represents locations within the original electronic file each of which corresponds to a respective portion of the biometric feature vector file. A given electronic file, which may be the original file or a modified version of it, is processed with each of the digital imprint files to generate a respective reconstructed biometric feature vector file. The reconstructed biometric feature vector files are compared to biometric feature vector files in storage (18) to associate the individual with the given electronic file. The method allows a given electronic file to be linked to the individual with a greater certainty than is possible by the use of fake objects, watermarks or digital signatures, even if the given electronic file has been created by substantial modification of the original electronic file.
The present invention provides a method for determining a Kidd (JK) blood group phenotype of a patient, the method comprising analysing the genetic sequence of the patient's blood group defining alleles; comparing that sequence to at least one of the JK reference sequences of SEQ ID NO: 19-22; and determining the level of homology between the patient's genetic sequence and the reference sequences(s), wherein homology of at least 80% indicates one of the patient's JK phenotypes as identified by the reference sequence and wherein homology of about 40% to about 60% indicates a hybrid phenotype. The present invention additionally provides a method for determining the RHD haplotype of a patient, the method comprising analysing the genetic sequence of the patient's blood group defining alleles; comparing that sequence to at least one of the RHD reference sequences of SEQ ID NOs:23-25; and determining the level of homology between the patient's genetic sequence and the reference sequence(s), wherein homology of at least 80% indicates one of the patient's RHD haplotypes as identified by the reference sequence
A method is provided for screening, risk assessment, prevention and early diagnosis of periodontal disease and/or peri-implantitis, patient-centred point-of-care periodontal therapy and monitoring treatment outcomes in a subject. The method comprises: collecting subgingival plaque samples from one or more sites around one or more teeth; extracting LPS from the or each sample; and assaying sub-gingival LPS activity after extraction, using recombinant Factor C.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
G01N 33/579 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving limulus lysate
A mechanical vocal apparatus is provided and comprises a mouth roof and a tongue. The contour of the mouth roof is fixed and the tongue is movable relative to the mouth roof to vary the cross sectional area therebetween so as to produce different sounds. The contour of the mouth roof is defined by mathematical optimisation.
There is provided a non-PCR based method for construction of a DNA recombination fragment with necessary flanking regions homologous to a desired site of genetic manipulation within a target DNA required for recombination-based manipulation of said target DNA, comprising the steps of: A) identifying a desired site of insertion for a genetic element in said target DNA; B) locating an endogenous, native, half-site of a selected restriction endonuclease present upstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 5' extent of an upstream homology region; C) locating an endogenous, native, half-site of the same selected restriction endonuclease present downstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 3' extent of a downstream homology region; D) synthesising a flanking region cassette resulting in juxtapositioning of the upstream and downstream half-sites thereby causing formation of complete restriction site for the selected restriction endonuclease flanked by said upstream and downstream homology regions; and E) inserting the flanking region cassette into a plasmid vector which includes the genetic element to be used to manipulate the target DNA, conferring upon the plasmid vector the necessary flanking homology regions for recombination within the said target DNA at the desired site of insertion.
The present invention provides an ATPase inhibitor for use in the treatment or prevention of tooth cell autophagy and/or for use in the treatment or prevention of autophagy in deciduous and/or permanent teeth. Methods of treatment of the same are also provided, as are compositions comprising a local anaesthetic and an ATPase inhibitor.
A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A bottom-fixed wave energy capture device is provided and comprises a foundation and an oscillating water column energy collector device. The device comprises a collection chamber and the chamber includes means for changing a position of a surface of the chamber so there is an increased surface area against which waves coming from a generally opposite direction impact.
F03D 9/00 - Adaptations of wind motors for special useCombinations of wind motors with apparatus driven therebyWind motors specially adapted for installation in particular locations
F03B 13/14 - Adaptations of machines or engines for special useCombinations of machines or engines with driving or driven apparatusPower stations or aggregates characterised by using wave or tide energy using wave energy
39.
VIRAL VECTORS ENCODING A DNA POLYMERASE WITH DECREASED PROOF-READING CAPACITY AND USES THEREOF
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (USA)
Inventor
Jarvis, Michael Arthur
Murphy, Aisling Aoife
Feldmann, Heinrich
Marzi, Andrea
Powers, Ilhem Messaoudi
Abstract
A recombinant herpesvirus-based vector comprising a nucleic acid sequence encoding a heterologous antigen and a promoter for controlling the expression of the antigen, in which the promoter is expressed at a time selected to provide a required immune response in a subject.
An apparatus and method for use in electrical conversion are described. The apparatus comprises a bridge rectifier (12) having an input side (14) and an output side (8), and a switched capacitor line (20) connected across the output side (18) of the rectifier (2), wherein the switched capacitor line (20) comprises a capacitor (22), a charging leg (24) and a switched discharge leg (26), and wherein the charging leg (24) incorporates a transistor (30) controlled so as to maintain a substantially constant charging current when the transistor (30) is conductive.
A DC-DC conversion scheme is described that comprises a buck converter including a first switch connected in series with a first inductor, the first switch and first inductor providing a switched connected between an input and an output, a second switch being connected across output, and a DC boost arrangement connected between the first switch and the first inductor, the DC boost arrangement comprising second and third magnetically linked inductors, the second inductor being connected in series between the first switch and the first inductor, and the third inductor being electrically connected to a point intermediate the first and second inductors, the windings of the second and third inductors being such that a change in current flowing through the second inductor induces a boost current in the third inductor supplementing the current flowing through the second inductor.
H02M 3/155 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only
H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load
A control arrangement for use in controlling the electrical supply from a power supply unit including an internal capacitance (16) to an output (30), the control arrangement comprising first and second magnetically linked inductors (24, 26) arranged in series with one another and defining therebetween a connection (40) by which they are interconnected, third and fourth magnetically linked inductors (34, 36) each being connected to the connection (40) between the first and second inductors (24, 26), switch means (52) providing switched connections between the third and fourth inductors (34, 36) and ground, and a controller50operable to control the operation of the switch means (52) such that closing of a switch of the switch means (52) results in the formation of an LCR circuit, the internal capacitance (16) forming the capacitance of the LCR circuit and the third or fourth inductor (34, 36) forming the inductance of the LCR circuit, the magnetic link between the third and fourth inductors (34, 36) allowing an output to be generated from the other of the third and fourth inductors (34, 36).
G05F 1/67 - Regulating electric power to the maximum power available from a generator, e.g. from solar cell
H02M 3/155 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only
A control arrangement for use in controlling the electrical supply from a power supply unit including an internal capacitance to an output is described, the control arrangement comprising an inductor (22) a switch (26) arranged in parallel with internal capacitance, and a controller (30) operable to control the operation of the switch (26) such that closing of the switch (26) results in the formation of an LCR circuit, the internal capacitance forming the capacitance of the LCR circuit. An associated control method is also described.
An electrical conversion apparatus is described which comprises a bridge rectifier (10) having an input side and an output side, and a switched capacitor line (16) arranged in parallel with the output side of the bridge rectifier (10), the switched capacitor line (16) comprising a capacitance (18) and a switch (20) arranged in series with one another so that the switch (20) can control charging and discharging of the capacitance (18). A method of electrical conversion is also disclosed wherein when the output voltage of the bridge rectifier is above a threshold level (26) and is rising the switch is closed so that the capacitance charges and a load is satisfied from the output of the bridge rectifier, when the output of the bridge rectifier is above the threshold level (26) and is falling the switch is opened so that the capacitance is isolated from the load, the load still being satisfied by the output of the bridge rectifier, and when the output of the bridge rectifier is below the threshold level (26), the switch is closed so that the load is served by discharge of the capacitance. The threshold level (26) may be dynamically controlled, for example in response to the output of a monitor circuit (32).
A method of testing water is described which comprises the steps of taking a sample to be tested, diluting the sample, applying a reagent to the sample, heating the sample for a predetermined period, and using the colour of the sample to provide an indication of the water quality.
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
A method of producing a product having a predetermined porosity comprises the following steps: conducting a porosity test upon a test sample; producing a 3 dimensional model of voids interconnected by throats; deriving an intrusion curve for the model; comparing the derived intrusion curve for the model with an intrusion curve showing the output of the porosity test; iteratively modifying the model until the derived intrusion curve for the model matches that for the output of the porosity test; making adjustments to at least one parameter of the model to adjust the porosity characteristics of the model to the predetermined porosity characteistics; and modifying the test sample in accordance with the adjustments.
Methods of tissue sample preparation and analysis are disclosed, in which a sample is prepared by digesting the tissue in acid, subsequently adding a non-ionic surfactant and diluting the digested tissue with water, wherein the concentration of the non-ionic surfactant in selected to disperse titanium dioxide nanoparticles present in the diluted sample; and agitating the sample immediately prior to analysis to further disperse the particles. Methods are disclosed wherein the concentration of the non-ionic surfactant in the diluted sample are above the critical micelle concentration. Methods are disclosed wherein the sample is subsequently analysed by inductively coupled plasma optical emission spectrometry (ICP- OES) to determine the concentration of metals including titanium in the form of titanium oxide nanoparticles and/or by inductively coupled plasma mass spertrometry (ICP-MS) to determine the characteristics of titanium dioxide nanoparticles in the sample. In some methods, the same prepared sample may be used for both ICP-OES and ICP-MS.
A method for processing a sample of maternal plasma comprising maternal free DNA and ffDNA is provided, the method comprising the in situ enrichment of the amount of ffDNA relative to the amount of maternal free DNA. In one embodiment, the amount of ffDNA in the sample is increased, for example by PCR methods. In a further embodiment, the amount of maternal free DNA in the sample is decreased, in particular by selective amplification, for example by PCR methods, and selective depletion. The method is particularly useful in the detection of genetic abnormalities in the fetus, in particular Down Syndrome and other aneuploidies.
A method for characterising an embryo is provided, the method comprising determining characteristics of the pattern of movement of the embryo; and comparing the determined characteristics with reference data relating to the expected movement pattern of the subject embryo. The method is of use in the staging of embryos and in analysing an environment to which the embryo has been exposed. A system for characterising an embryo is also provided.
A fermented foodstuff composition for human consumption is provided, the foodstuff composition being prepared by the fermentation of a foodstuff substrate with a lactic acid producing bacteria, the lactic acid bacteria being characterised by: a) being viable under the conditions prevailing in the human gastrointestinal tract; b) being a bacteria capable of aggregating and/or coaggregating with one or more pathogens; and c) being able to produce upon fermentation in the foodstuff substrate lactic acid in an amount of at least a minimum inhibitory concentration of lactic acid.
36 - Financial, insurance and real estate services
38 - Telecommunications services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Business administration; business management services; office functions; rental of office machinery and equipment; human resources management and administration including personnel recruitment and placement services; provision of office facilities; hiring of office equipment; business advice; business development services. Leasing of office space; Rental of office space; hire of office space. Telecommunications services; portal services; e-mail services; providing user access to the Internet. Education; providing of training; cultural activities. Scientific and technological services and research and design relating thereto; industrial analysis and research services.
A fermented liquid feed composition for a target animal is provided, the feed composition being prepared by the fermentation of a feed substrate with a lactic acid producing bacteria, the lactic acid bacteria being characterised by: a) being viable under the conditions prevailing in the gastrointestinal tract of the target animal; b) being an aggregating bacteria and/or co-aggregating with one or more pathogens; and c) being able to produce upon fermentation in the feed substrate lactic acid in an amount of at least a minimum inhibitory concentration of lactic acid. A method of producing a fermented liquid feed composition is also provided. Preferred lactic acid producing bacteria for use in the composition and method are Lactobacillus.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific apparatus and instruments for the thermal separation of chemical compounds; scientific measuring apparatus for the thermal separation of chemical compounds. Technological advisory services; technological research; advisory services relating to technological research; preparation of technological reports; services for the provision of technological information; technological advisory services relating to computer programs; technological analysis services; technological services relating to design; advisory services relating to scientific research; preparation of reports relating to scientific research; research (scientific- ); advisory services relating to computer systems design; computer design research; computer design services; computer hardware design services; computer software design services; design of computer programs; programming (computer- ) services; installation, maintenance and repair of computer software; computer consultancy; industrial research; creating and maintaining web sites; creating and maintaining web sites for others.
55.
A METHOD OF COLOURING TIN AND TIN-CONTAINING ARTICLES
A method of colouring the surface of a tin-containing article is provided, the method comprising contacting at least a portion of the surface of the article with a solution comprising a thiosulphate, preferably under substantially neutral or acidic conditions. In one embodiment, the solution contains sodium thiosulphate and citric acid and further comprises a copper salt, together with acetone and/or glycerol. The method is preferably conducted at elevated temperatures, in particular by heating the solution to a temperature of from 45 to 85 °C. The method is particularly suitable for the colouring of pewter articles, but may be applied to a wide range of tin-containing materials and tin alloys.
C23C 22/68 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions using aqueous solutions with pH between 6 and 8
G01K 11/14 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance of inorganic materials
56.
METHOD FOR PREDICTION AND DIAGNOSIS OF MEDICAL CONDITIONS AND APPARATUS FOR PERFORMING THE SAME
A method of characterising a medical condition of a subject is provided, the method comprising the steps of: a) provide a set of symptom data for the subject, the set of symptom data comprising at least one result of an analysis Xi conducted on the subject; b) calculate a diagnostic coefficient DCi for each result of an analysis Xi c) calculate an importance factor Ji for each result of an analysis Xi; d) specify an acceptable level of error in the characterisation; e) determine the thresholds for the diagnostic coefficients DCi using the error level specified in step (d) and define a threshold range therebetween; f) compare the value of the diagnostic coefficient DCi of the analysis Xi with the highest importance factor Ji DCimax with the thresholds determined in step (e); g) successively sum the diagnostic coefficient DCimax with the diagnostic coefficient DCi having the next highest importance factor Ji until the value of the sum lies outside the threshold range defined in step (e); and h) identify the threshold exceeded in step (g). The method preferably comprises the step of converting continuous data in the symptom data set into discrete data. A system for carrying out the method is also disclosed.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
57.
METHOD AND APPARATUS FOR DETERMINING THE SPEED AND ORIENTATION OF NETWORKED MOBILE STATIONS
A method of estimating the speed of movement of a mobile device of a wireless communication system comprises the steps of determining the distance of the mobile device from a reference device at a first time instant; determining the distance of the mobile device from the reference device at a second time instant; calculating the distance travelled by the mobile device between the first time instant and the second time instant; and estimating the speed of movement of the mobile device from the calculated distance and the time elapsed between the first time instant and the second time instant. The distances from the reference device to other mobile devices in the system may then be determined using relative distance measurements at successive time instants. An apparatus for performing the method and a wireless communications network comprising the apparatus are also provided.
G01S 5/02 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations using radio waves
G01S 11/02 - Systems for determining distance or velocity not using reflection or reradiation using radio waves
An apparatus for enhancing proprioception in the foot of a subject comprising a member having a surface for contacting the sole of the foot of the subject, and structures disposed on the surface of the member for applying increased pressure to nerve endings of the subjects foot whilst in use, thereby increasing the proprioception of the subject. An embodiment of the invention is an inside having protrusions.
An apparatus is provided that responds to the varying pressures applied to the foot of a subject during different activities, in particular walking, jogging and running, comprising a member (4) with a surface (6) for contacting the plantar surface of the foot of the subject; and structures (10) for absorbing and reacting to various pressures in the foot whilst in use. The structures preferably extend from the surface of the member -and are in the form of units (12) having a longitudinal axis extending in the direction of expected impact from the foot of the user, the units being compressible under the action of pressure from the foot, the resistance of the units to compression increasing progressively or stepwise as the unit is compressed. The units are preferably hollow and have an internal or external taper to provide the variable resistance to compression.
There is provided an isoprenoid according to the general formula (I) wherein R1 and R2 are independently selected from H and alkyl; and R3, R4, R5 and R6 are independently selected from groups of the general formula (II) and (III) wherein R7 and R8 each represent a group of general formula CO - R9, in which each R9 is independently selected from H, OH, alkyl and alkoxy groups, or R7 and/or R8 present in R3 and R4 and/or in R5 and R6 combine to form a group of the general formula (IV) wherein R10 is selected from OH and alkoxy; or salts thereof. The isoprenoids are of particular use in the preparation of liposomes, for use in the delivery of pharmaceutically active components to a subject human or animal.
C07C 69/608 - Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a ring other than a six-membered aromatic ring in the acid moiety
A method of processing a received concatenated code codeword is disclosed, the concatenated code codeword comprising a plurality of inner code codewords and one or more outer code codewords, each inner code codeword comprising symbols, from each outer code codeword comprising one or more information symbols and one or more parity symbols, the parity symbols in eeach outer code codeword corresponding to the parity check equations of the outer code. The method comprises (i) decoding the received concatenated code codeword; (ii) erasing a subset of the received inner code codewords; and (iii) determining a replacement inner code codeword to replace each of the erased inner code codewords to provide a candidate concatenated code codeword. A preferred method further comprises (iv) erasing a further, different subset of the received inner code codewords; (v) determining further replacement inner code codewords to replace each of the thus erased inner code codewords to provide a further candidate concatenated code codeword; and (vi) determining the candidate concatenated code codeword having the highest correlation with the received vector of the decoded concatenated code codeword. A system for performing the method is also disclosed.
H03M 13/29 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes combining two or more codes or code structures, e.g. product codes, generalised product codes, concatenated codes, inner and outer codes
62.
METHOD OF DETECTING CARRIER SPIN POLARISATION AND APPARATUS FOR THE SAME
A method of detecting spin polarization in a subject material comprises applying a potential difference across the subject material causing an electrical current to flow across the material, thereby inducing carrier polarization within the material in a direction perpendicular to the direction of current flow, carriers of one spin orientation concentrating at a first edge of the subject material and carriers of the opposite orientation concentrating at a second edge of the material, opposite to the first edge under the action of the Spin Hall Effect (SHE); allowing spin polarized carriers to tunnel into a ferromagnetic material from the subject material in at least a portion adjacent one of the first or second edges of the subject material; and measuring the tunneling magnetoresistance (TMR) between the ferromagnetic material and the subject material at the first or second edge. An apparatus for analyzing carrier spin polarization comprises a subject material; means for applying an electric field to the subject material so as to induce a current to flow through the subject material, thereby inducing spin polarization of carriers at opposing first and second edges of the subject material in a direction perpendicular to the electric field under the action of the spin Hall effect (SHE); a ferromagnetic material in contact with at least a portion adjacent one of the first or second edges of the subject material; and means for measuring the tunneling magnetoresistance between the ferromagnetic material and the subject material at the first or second edge.
A method for the preparation of sculpted objects comprises the steps: (a) scanning at least a portion of the object to be sculpted to prepare an image data set; (b) modifying the image data set; and (c) preparing a completed sculpture using the modified image data set. The method preferably comprises the steps of (a) assessing an object to be sculpted and identifying portions of the object with a level of detail greater than a predetermined threshold; (b) scanning the object with the exception of the portions identified in step (a) to have detail above the predetermined threshold to provide an image data set; (c) modifying the image data set to include data for the omitted portions, to provide a complete image data set for the object; and preparing a completed sculpture using the modified data set. In an alternative method, the sculpture is prepared by the steps of (a) scanning a portion of an object to provide an image data set; (b) preparing a partial sculpture of the scanned portion of the object using the image data set using a first technique; and (c) preparing a full sculpted object using a second technique. Method preferably employs rapid prototyping to convert the image data set into a three-dimensional replica or finished sculpture.
B44B 1/02 - Artists' machines or apparatus equipped with tools or work holders moving, or able to be controlled, three-dimensionally for making single sculptures or models wherein three-dimensional copies are made
B44B 1/00 - Artists' machines or apparatus equipped with tools or work holders moving, or able to be controlled, three-dimensionally for making single sculptures or models
G05B 19/42 - Recording and playback systems, i.e. in which the programme is recorded from a cycle of operations, e.g. the cycle of operations being manually controlled, after which this record is played back on the same machine
A method for providing a navigable virtual display, the comprises the steps of: providing a panoramic image of a space or location; preparing a navigable virtual panoramic image data set based upon the virtual image of the space; providing a multidimensional image of an object to be viewed; preparing a multidimensional image data set from the multidimensional image; and incorporating the multidimensional image data set into the virtual panoramic image data set to provide a virtual panoramic display image data set; wherein, when displayed, the virtual panoramic display image data set provides a navigable virtual panoramic display of the imaged object in an image of the space or location. A system is also provided for displaying the virtual panoramas. The method and system may be used to display images of interior or exterior locations. The method and system find particular use in the exhibiting of museum artifacts and art collections and as an aid in navigation.
