A system is provided for estimating a mass of a vehicle. The system includes a torsion sensor (e.g., provided by strain gauges) provided on at least a drive axle of the vehicle and configured to measure torsion in the drive axle between a drive input and a load of the drive axle. The system also includes at least one speed sensor configured to measure a speed of the drive axle and at least one sensor configured to measure or derive an inclination. A control module which is communicatively coupled to the torsion sensor, the speed sensor, and the sensor to measure or derive the inclination, thereby to receive signals from the sensors indicative of the characteristics they measure. The control module is configured to estimate the mass of the vehicle based on the signals from the sensors by solving an equation of motion based on the received signals.
This invention relates to a method 20, 30 of issuing and verifying certificates. The method includes receiving 21, at an NFT assigner 14, a request from an issuer 12 to issue an NFT associated with a certificate. The NFT assigner then validates 22, using a validation module 14.2, the request using cryptographic techniques, ensuring that the request is authentic and authorized. Once the request is validated, the NFT assigner 14 generates 23, using an NFT generator 14.1, a unique and non-interchangeable NFT associated with the certificate. The NFT is then stored or recorded 24 on the blockchain network 16, providing an immutable and transparent record of ownership and authenticity. The NFT assigner 14 then issues 26 the generated NFT to the issuer 12 through the API, providing a standardized and secure way to retrieve the NFT and verify authenticity of the certificate thus preventing fraudulent falsification of degree certificates.
H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
AFRICAN HEALTH RESEARCH INSTITUTE (AHRI) (South Africa)
UNGANGEZULU INDIGENOUS REMEDIES (PTY) LTD. (South Africa)
DURBAN UNIVERSITY OF TECHNOLOGY (South Africa)
UNIVERSITY OF KWAZULU-NATAL (South Africa)
Inventor
Gqaleni, Nceba
Maharaj, Vinesh
Nkabinde, Siphatimandla, Authority
Nkabinde, Magugu, Welcome
Invernizzi, Luke
Mc Millan, Patrick, Matthew
Tembeni, Babalwa
Abstract
Pentanisia pruneillloides, Senna italica, Gnidia Sclerocarya birreaSclerocarya birrea. The invention further relates to methods of treatment of HIV-1 with the herbal composition as well as methods of preparation of the herbal composition.
This invention relates to an immunogen comprising a gonadotropin releasing hormone (GnRH) peptide sequence, a kisspeptin peptide sequence and a stimulant of raising an immune response, such an immunogen for use in a method to regulate the release of hormones in a vertebrate including modulation of reproductive hormones, to reduce fertility in a vertebrate and to treat hormone-dependent diseases including hormone-dependent tumours including prostate tumours, breast, ovary and endometrial tumours, benign hyperplasia including benign prostatic hyperplasia and uterine fibroids, endometriosis, polycystic ovarian disease, infertility, sexual dysfunction and any disorder that would benefit from an increased or decreased GnRH-dependent activity and a vaccine formulation comprising the immunogen. The invention also relates to the use of the immunogen in the preparation of a medicament for use in a method to regulate the release of hormones in a vertebrate.
The present invention relates to a topical composition comprising a 100 μg/mL ethanolic extract from the plant Aspalathus linearis together with a dermatologically acceptable carrier for use in a method of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject. The invention further relates to methods of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject.
THIS invention relates to the synthesis of derivatives of siphonochilone and therapeutic use thereof in the treatment and prevention of respiratory virus disease, in particular influenza or a coronavirus disease.
A61K 31/343 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
7.
MICELLAR MYCOLATE COATED CARBON ELECTRODES FOR ELECTROCHEMICAL IMPEDANCE IMMUNOASSAY
A method of forming a solution of mycolic acid antigens for immobilisation on a substrate is provided. The method comprises heating a mixture of mycolic acid and a polar organic solvent to a temperature higher than the melting point of the mycolic acid, thus producing a solution of mycolic acid antigens in the polar solvent, wherein the solution is a micellar solution.
The invention provides a method of producing a carbonate or a bicarbonate of an alkali metal, in solid form, from a sulphate of the alkali metal. The method includes, in a first reaction step, reacting, in aqueous medium, a sulphate of an alkali metal with one or more alkaline earth metal sulphides, thus forming an aqueous solution of one or more sulphides of the alkali metal and one or more sulphates of the alkaline earth metal in solid form. The method also includes, in a second reaction step, in the aqueous solution of one or more sulphides of the alkali metal, reacting the one or more sulphides of the alkali metal with carbon dioxide (CO2) in gaseous form, thus forming an aqueous solution of a bicarbonate of the alkali metal and gaseous hydrogen sulphide. The method further includes, in a recovery step, recovering a carbonate or the bicarbonate of the alkali metal, in solid form, from the aqueous solution of the bicarbonate of the alkali metal.
The invention provides a solar collector arrangement which includes a reflector (12), a collector (14) and a support arrangement (16). The support arrangement is configured to permit relative displacement of the reflector and the collector between an operative condition, in which the collector is positioned to receive reflected radiation from the reflector, and a stowed condition. In the stowed condition, the spacing between the reflector and the collector is less than in the operative condition and the wind loading on the solar collector arrangement is less than in the operative condition. The invention extends to a solar assembly which includes a mobile platform on which the solar collector arrangement is mounted.
This invention relates to a method (30) and system (10) for evaluating circuit protection of a power network. The method (30) includes simulating (32) a multisource, interconnected power network (40) comprising circuit protection elements (A, B, C, D), setting (33) circuit protection element parameters for each circuit protection element, simulating (35) at least one fault (42) on the power network (40) at a predetermined fault position for a predefined simulation time. In a next step, the method includes calculating (38) conductor LTE exposure and determining (39) an LTE threshold. Furthermore, the method (30) includes simultaneously graphically representing (41) a three-dimensional visualisation of the conductor LTE exposure (50) for the predefined simulation time and the LTE threshold (51), on the same three-dimensional visualisation. The method provides a wholistic approach for simulating and determining a dynamic effect of faults for chosen circuit protection settings on conductor LTE exposure compared to LTE thresholds.
G06F 30/367 - Design verification, e.g. using simulation, simulation program with integrated circuit emphasis [SPICE], direct methods or relaxation methods
The invention provides a carbonaceous feed pyrolysis apparatus including two or more hot particle fluidised beds, and material transfer means for the transfer of hot catalyst particles between two or more of the beds, wherein one or more of the 5 fluidised beds is a gasifier which contains a gasification zone and one or more of the fluidised beds is a pyrolysis reactor which contains a pyrolysis zone, so that the particles are recirculated and serve as an energy carrier to drive pyrolysis in the pyrolysis zone. The invention extends to a carbonaceous feed pyrolysis process using said apparatus.
C10B 49/22 - Destructive distillation of solid carbonaceous materials by direct heating with heat-carrying agents including the partial combustion of the solid material to be treated with moving solid heat-carriers in divided form in dispersed form according to the "fluidised bed" technique
C10B 57/06 - Other carbonising or coking processesFeatures of destructive distillation processes in general using charges of special composition containing additives
C10B 57/00 - Other carbonising or coking processesFeatures of destructive distillation processes in general
The invention provides a pharmaceutical composition suitable for topical application. The pharmaceutical composition comprises an extract of Plectranthus aliciae and a pharmaceutically acceptable carrier. The invention extends to provide a pharmaceutical composition for the treatment of acne, a pharmaceutical gel composition, a substance or composition comprising an extract of Plectranthus aliciae, a use of a Plectranthus aliciae extract, and various methods of preventing or treating acne.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A system is provided for estimating a mass of a vehicle. The system includes a torsion sensor (e.g., provided by strain gauges) provided on at least a drive axle of the vehicle and configured to measure torsion in the drive axle between a drive input and a load of the drive axle. The system also includes at least one speed sensor configured to measure a speed of the drive axle and at least one sensor configured to measure or derive an inclination. A control module which is communicatively coupled to the torsion sensor, the speed sensor, and the sensor to measure or derive the inclination, thereby to receive signals from the sensors indicative of the characteristics they measure. The control module is configured to estimate the mass of the vehicle based on the signals from the sensors by solving an equation of motion based on the received signals.
The invention provides an aggregate and a method of manufacturing an aggregate which is suitable for use in concrete. The aggregate includes as a primary constituent, fly ash. The method includes mixing particulate fly ash and a binder to form a dry mixture. The dry mixture 5 is formed into aggregate elements in a granulator after which the aggregate elements are hardened by heat treatment.
C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (South Africa)
UNIVERSITY OF PRETORIA (South Africa)
Inventor
Pillay, Priyen
Singh, Advaita Acarya
Tsekoa, Tsepo Lebiletsa
Chikwamba, Rachel Kerina
Vorster, Juan Barend
Kunert, Karl Josef
Abstract
NbNbNbNbVPE-1b, in a plant, including with the expression a genome editing vector for targeted mutagenesis of the cysteine protease(s). The invention further relates to a method of increasing the yield and/or quality of recombinant proteins in the plant where expression of the one or more cysteine protease(s) has been downregulated in accordance with the method of the invention.
The present invention relates to a topical composition comprising a 100 µg/mL ethanolic extract from the plant Aspalathus linearis together with a dermatologically acceptable carrier for use in a method of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject. The invention further relates to methods of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
The present invention relates to the field of cementitious compositions. Particularly, the invention concerns an alkaline-activated fly ash cementitious composition and the use of this composition as a binder in concrete production.
C04B 28/18 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing mixtures of the silica-lime type
C04B 22/10 - Acids or salts thereof containing carbon in the anion, e.g. carbonates
The present invention relates to lipid-modified starches. It provides a process for preparing a lipid-modified starch paste, which includes the steps of combining starch with a lipid component, the lipid component being selected from any one of monoglyceride and ascorbyl palmitate, to provide a suspension, and heat processing the suspension to form the lipid-modified starch paste. The invention also provides a lipid-modified starch paste, which includes a plurality of spherical micro-particles, each spherical micro-particle having a starch core with an amylose-lipid complex layer on an outer surface of the starch core, the amylose-lipid complex layer operable to regulate water absorption capability of the starch core. The invention further extends to provide various uses of a lipid-modified starch paste as a partial or total fat and/or oil replacement in a foodstuff, an improved fat- and/or oil-containing foodstuff and in particular, a low-calorie mayonnaise.
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
A23L 29/212 - StarchModified starchStarch derivatives, e.g. esters or ethers
This invention relates to an immunogen comprising a gonadotropin releasing hormone (GnRH) peptide sequence, a kisspeptin peptide sequence and a stimulant of raising an immune response, such an immunogen for use in a method to regulate the release of hormones in a vertebrate including modulation of reproductive hormones, to reduce fertility in a vertebrate and to treat hormone-dependent diseases including hormone-dependent tumours including prostate tumours, breast, ovary and endometrial tumours, benign hyperplasia including benign prostatic hyperplasia and uterine fibroids, endometriosis, polycystic ovarian disease, infertility, sexual dysfunction and any disorder that would benefit from an increased or decreased GnRH-dependent activity and a vaccine formulation comprising the immunogen. The invention also relates to the use of the immunogen in the preparation of a medicament for use in a method to regulate the release of hormones in a vertebrate.
This invention relates to an immunogen comprising a gonadotropin releasing hormone (GnRH) peptide sequence, a kisspeptin peptide sequence and a stimulant of raising an immune response, such an immunogen for use in a method to regulate the release of hormones in a vertebrate including modulation of reproductive hormones, to reduce fertility in a vertebrate and to treat hormone-dependent diseases including hormone-dependent tumours including prostate tumours, breast, ovary and endometrial tumours, benign hyperplasia including benign prostatic hyperplasia and uterine fibroids, endometriosis, polycystic ovarian disease, infertility, sexual dysfunction and any disorder that would benefit from an increased or decreased GnRH-dependent activity and a vaccine formulation comprising the immunogen. The invention also relates to the use of the immunogen in the preparation of a medicament for use in a method to regulate the release of hormones in a vertebrate.
The invention provides a method of producing a carbonate or a bicarbonate of an alkali metal, in solid form, from a sulphate of the alkali metal. The method includes, in a first reaction step, reacting, in aqueous medium, a sulphate of an alkali metal with one or more alkaline earth metal sulphides, thus forming an aqueous solution of one or more sulphides of the alkali metal and one or more sulphates of the alkaline earth metal in solid form. The method also includes, in a second reaction step, in the aqueous solution of one or more sulphides of the alkali metal, reacting the one or more sulphides of the alkali metal with carbon dioxide (CO2) in gaseous form, thus forming an aqueous solution of a bicarbonate of the alkali metal and gaseous hydrogen sulphide. The method further includes, in a recovery step, recovering a carbonate or the bicarbonate of the alkali metal, in solid form, from the aqueous solution of the bicarbonate of the alkali metal.
22) in gaseous form, thus forming an aqueous solution of a bicarbonate of the alkali metal and gaseous hydrogen sulphide. The method further includes, in a recovery step, recovering a carbonate or the bicarbonate of the alkali metal, in solid form, from the aqueous solution of the bicarbonate of the alkali metal.
This invention relates to a method (30) and system (10) for evaluating circuit protection of a power network. The method (30) includes simulating (32) a multisource, interconnected power network (40) comprising circuit protection elements (A, B, C, D), setting (33) circuit protection element parameters for each circuit protection element, simulating (35) at least one fault (42) on the power network (40) at a predetermined fault position for a predefined simulation time. In a next step, the method includes calculating (38) conductor LTE exposure and determining (39) an LTE threshold. Furthermore, the method (30) includes simultaneously graphically representing (41) a three-dimensional visualisation of the conductor LTE exposure (50) for the predefined simulation time and the LTE threshold (51), on the same three-dimensional visualisation. The method provides a wholistic approach for simulating and determining a dynamic effect of faults for chosen circuit protection settings on conductor LTE exposure compared to LTE thresholds.
G06F 30/367 - Design verification, e.g. using simulation, simulation program with integrated circuit emphasis [SPICE], direct methods or relaxation methods
G06F 30/31 - Design entry, e.g. editors specifically adapted for circuit design
G06F 119/02 - Reliability analysis or reliability optimisationFailure analysis, e.g. worst case scenario performance, failure mode and effects analysis [FMEA]
G06F 119/06 - Power analysis or power optimisation
24.
Anticancer Activity of Buddleja Saligna Compositions
The invention relates to an extract from Buddleja saligna, or a bioactive mixture consisting essentially of oleanolic acid and ursolic acid isolated from Buddleja saligna, for use in preventing and/or treating skin cancer, more specifically melanoma, and for reducing skin damage resulting from UV radiation. The invention also relates to uses and methods of treating skin cancer and reducing skin damage resulting from UV radiation using the extracts and/or bioactive mixture described. The invention further relates to an anticancer composition comprising the extracts and/or bioactive mixture, that inhibits angiogenesis and/or proliferation of cells associated with melanoma, as well as a sunscreen composition comprising the extracts and/or bioactive mixture.
The invention provides a system for manufacturing graphene wool which includes a receptacle, a graphene growth substrate locatable inside the receptacle, a heating device for increasing the temperature inside the receptacle, an inlet gas flow communication with the receptacle for controlling the introduction of gaseous substances into the receptacle, and a cooling device for rapidly decreasing the temperature inside the receptacle. The invention extends to a method for manufacturing graphene wool and to an air pollutant trap which includes: a sorbent, and a housing for housing the sorbent, wherein the sorbent includes graphene.
B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
B01J 19/14 - Production of inert gas mixturesUse of inert gases in general
C01B 32/186 - Preparation by chemical vapour deposition [CVD]
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
The invention provides a carbonaceous feed pyrolysis apparatus including two or more hot particle fluidised beds, and material transfer means for the transfer of hot catalyst particles between two or more of the beds, wherein one or more of the 5 fluidised beds is a gasifier which contains a gasification zone and one or more of the fluidised beds is a pyrolysis reactor which contains a pyrolysis zone, so that the particles are recirculated and serve as an energy carrier to drive pyrolysis in the pyrolysis zone. The invention extends to a carbonaceous feed pyrolysis process using said apparatus.
C10B 49/22 - Destructive distillation of solid carbonaceous materials by direct heating with heat-carrying agents including the partial combustion of the solid material to be treated with moving solid heat-carriers in divided form in dispersed form according to the "fluidised bed" technique
C10B 53/02 - Destructive distillation, specially adapted for particular solid raw materials or solid raw materials in special form of cellulose-containing material
C10B 57/06 - Other carbonising or coking processesFeatures of destructive distillation processes in general using charges of special composition containing additives
C10J 3/46 - Gasification of granular or pulverulent fuels in suspension
The invention is directed at a method of encapsulating mycolic acid antigen in carbon, wherein carbon and mycolic acid antigen are dissolved in solution, the solution is ultrasonicated, and dried. The invention is also directed to a carbon-encapsulated mycolic acid antigen produced by this method for use as an electrochemical immunosensor for detection of tuberculosis by detecting presence of mycolic acid antibodies in a serum sample.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/551 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
The invention is directed at isolated probiotic bacteria, that has been isolated from bovine tissue including liver tissue and intestinal tissue, for the synthesis of vitamin A in the form of retinol and/or β-carotene. The invention is also directed at a composition comprising the isolated probiotic bacteria, where such composition can be in the form of a synbiotic food, such bacteria being able to colonize with human gut cells and produce retinol and/or β-carotene in the human gut.
A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
A23L 5/44 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
An antenna array is configured for signal jamming and comprises at least two antennas each configured to receive an incoming signal and transmit a retrodirective retransmitted signal based on the incoming signal and at least two repeater components. Each one of the antennas has one of the repeater components coupled thereto. Each one of the repeater components is configured to utilize a reference signal which is common to all of the repeater components. Each one of the repeater components is configured to negate a phase of the retransmitted signal relative to the incoming signal of its coupled antenna as a function of at least the reference signal, at least one of the repeater components is further configured to introduce at least a phase adjustment to the retransmitted signal. In this way, an angular error may be induced in a threat radar.
The present invention relates to a method of detecting the presence of an antibody to an avian influenza hemagglutinin antigen in a sample from a subject, wherein the antibody binds to an epitope of an avian influenza hemagglutinin antigen, comprising the steps of cloning a nucleic acid encoding an avian influenza antigen into a vector, infiltrating a plant cell with the vector, recovering the antigen from the plant, contacting the sample with the antigen, and detecting the formation of an antibody-antigen complex, wherein the antibody-antigen complex comprises antibodies in the sample bound to the antigen and wherein the formation of an antibody-antigen complex confirms that the subject has been exposed to an avian influenza hemagglutinin antigen. The present invention also relates to a device for assaying the presence of an antibody to avian influenza hemagglutinin antigen in a sample from a subject.
This invention relates to a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, a kit for performing the method, and furthermore to isolated nucleotide sequences being complementary to one or more mutations of the CFTR gene. According to a first aspect of the invention there is provided a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, including the steps of providing one or more nucleic acid sequences, fully complementary to one or more segments of the CFTR gene, wherein the one or more nucleic acid sequences correspond to the mutation to be identified; providing a biological sample of an individual to be tested for CF; isolating nucleic acids from the biological sample; and testing the biological sample for the presence of one or more of the nucleic acid sequences using a suitable detection method.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids
Electrical protection system for detection and isolation of faults in power distribution using synchronized voltage measurements and a method of its application
An electrical protection system arranged to detect and isolate faults either in a electrical power distribution. The system comprises at least a first busbar and a second busbar in electrical communication with each other through s powerline having a first end electrically coupled to the first busbar by a first circuit breaker and a second end connected to the second busbar by a second circuit breaker. It is connected to the at least two busbars, and configured to simultaneously collect/determine a first electrical quantity at each of the at least two busbars and compare the collected/determined electrical quantity to a second. When the first electrical quantity value less than the second quantity value, the system causes the first and second circuit breakers to open so as to decouple the electrical connection between first and second busbars. The system 100 detects and isolates fault efficiently while using voltage measurements.
H02H 7/22 - Emergency protective circuit arrangements specially adapted for specific types of electric machines or apparatus or for sectionalised protection of cable or line systems, and effecting automatic switching in the event of an undesired change from normal working conditions for distribution gear, e.g. bus-bar systemsEmergency protective circuit arrangements specially adapted for specific types of electric machines or apparatus or for sectionalised protection of cable or line systems, and effecting automatic switching in the event of an undesired change from normal working conditions for switching devices
H02H 1/00 - Details of emergency protective circuit arrangements
33.
Negative-resistance circuit and active filter for millimetre wave frequencies
This invention relates to an air valve which includes a deflector positioned inside a float chamber in order to improve the flow of air through the air valve. Further, the air valve includes an upper opening leading from the float chamber and having a transverse cross-section which increases away from the float chamber in order to smooth air flow. The invention further relates to an air valve accessory whereby an air valve can be modified in order to improve air flow therethrough.
The present invention relates to the field of cementitious compositions. Particularly, the invention concerns an alkaline-activated fly ash cementitious composition and the use of this composition as a binder in concrete production.
C04B 28/00 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
The present invention relates to lipid-modified starches. It provides a process for preparing a lipid-modified starch paste, which includes the steps of combining starch with a lipid component, the lipid component being selected from any one of monoglyceride and ascorbyl palmitate, to provide a suspension, and heat processing the suspension to form the lipid-modified starch paste. The invention also provides a lipid-modified starch paste, which includes a plurality of spherical micro-particles, each spherical micro-particle having a starch core with an amylose-lipid complex layer on an outer surface of the starch core, the amylose-lipid complex layer operable to regulate water absorption capability of the starch core. The invention further extends to provide various uses of a lipid-modified starch paste as a partial or total fat and/or oil replacement in a foodstuff, an improved fat- and/or oil-containing foodstuff and in particular, a low-calorie mayonnaise.
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
The invention relates to a drive arrangement for displacing a rotatable component. The drive arrangement includes a plurality of gear trains and a power source connected to each train and configured such that they are able to drive a rotating component selectively rotationally about an axis of rotation and/or laterally relative to the axis of rotation. The drive arrangement includes a plurality of rotating components typically constituting at least two planetary gear sets which are connected in series.
F16H 37/08 - Combinations of mechanical gearings, not provided for in groups comprising essentially only toothed or friction gearings with a plurality of driving or driven shaftsCombinations of mechanical gearings, not provided for in groups comprising essentially only toothed or friction gearings with arrangements for dividing torque between two or more intermediate shafts with differential gearing
B23Q 1/25 - Movable or adjustable work or tool supports
B23Q 1/54 - Movable or adjustable work or tool supports using particular mechanisms with rotating pairs only two rotating pairs only
A second-order all-pass network has at least three Second Generation Current Conveyors (CCIIs). A network input is connected or connectable to a Y port of a first CCII, a Z port of the first CCII is connected to a Y port of a second CCII, an X port of the first CCII is connected to a Y port of a third CCII, and a network output is connected or connectable, directly or indirectly, to a Z port of the second CCII. The X port of the first CCII is connected via a first network element to ground, the Z port of the first CCII is connected via a second network element to ground, an X port of the third CCII is connected via a third network element to ground, and an X port of the second CCII is connected via a fourth network element to ground.
The invention provides a method of and an arrangement for detecting leakage from a pipeline installed in a substrate. The arrangement includes a fibre-optic cable positioned in the substrate in the vicinity of the pipeline and a strain monitoring arrangement configured to monitor strain in the fibre-optic cable and to detect localized changes in the monitored strain. A processor is provided to which the strain monitoring arrangement is connected and which is configured to determine whether the detected change in strain is indicative of a leak in the pipeline and to generate a signal in response thereto.
A method of estimating vibration characteristics of moving rotor blades in a turbomachine comprising a housing and rotor including a shaft with the rotor blades attached thereto includes measuring, by at least one proximity sensor, a Time-of-Arrival (ToA) of a proximate tip of a moving rotor blade. The method includes manipulating, by a control module, timing data to determine a corresponding blade tip deflection at each measured ToA, expressing blade tip vibration behaviour as a Bayesian statistical model consisting of intermediate model parameters, wherein model coefficients in the statistical model are probabilistic quantities as opposed to conventional, deterministic quantities, and expressing, by the control module, the determined blade tip deflections as observed values in the statistical model. The method includes manipulating the intermediate model parameters in the statistical model using Bayesian linear regression or inference to estimate the intermediate model parameters and consequently the vibration behaviour of the rotor blade.
The invention provides a system for manufacturing graphene wool which includes a receptacle, a graphene growth substrate locatable inside the receptacle, a heating device for increasing the temperature inside the receptacle, an inlet gas flow communication with the receptacle for controlling the introduction of gaseous substances into the receptacle, and a cooling device for rapidly decreasing the temperature inside the receptacle. The invention extends to a method for manufacturing graphene wool and to an air pollutant trap which includes: a sorbent, and a housing for housing the sorbent, wherein the sorbent includes graphene.
B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
The invention relates to an extract from Buddleja saligna, or a bioactive mixture consisting essentially of oleanolic acid and ursolic acid isolated from Buddleja saligna, for use in preventing and/or treating skin cancer, more specifically melanoma, and for reducing skin damage resulting from UV radiation. The invention also relates to uses and methods of treating skin cancer and reducing skin damage resulting from UV radiation using the extracts and/or bioactive mixture described. The invention further relates to an anticancer composition comprising the extracts and/or bioactive mixture, that inhibits angiogenesis and/or proliferation of cells associated with melanoma, as well as a sunscreen composition comprising the extracts and/or bioactive mixture.
A61K 36/53 - Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
A61K 8/00 - Cosmetics or similar toiletry preparations
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
THIS INVENTION relates electrical protection system arranged to detect and isolate faults either in a electrical power distribution. The system comprises at least a first busbar and a second busbar in electrical communication with each other through s powerline having a first end electrically coupled to the first busbar by a first circuit breaker and a second end connected to the second busbar by a second circuit breaker. It is connected to the at least two busbars, and configured to simultaneously collect/determine a first electrical quantity at each of the at least two busbars and compare the collected/determined electrical quantity to a second. When the first electrical quantity value less than the second quantity value, the system causes the first and second circuit breakers to open so as to decouple the electrical connection between first and second busbars. The system 100 detects and isolates fault efficiently while using voltage measurements.
H02H 3/30 - Emergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition, with or without subsequent reconnection responsive to difference between voltages or between currentsEmergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition, with or without subsequent reconnection responsive to phase angle between voltages or between currents involving comparison of the voltage or current values at two spaced portions of a single system, e.g. at opposite ends of one line, at input and output of apparatus using pilot wires or other signalling channel
H02H 7/26 - Sectionalised protection of cable or line systems, e.g. for disconnecting a section on which a short-circuit, earth fault, or arc discharge has occurred
45.
A SECOND GENERATION CURRENT CONVEYOR (CCII) HAVING A TUNABLE FEEDBACK NETWORK
A Second-Generation Current Conveyor (CCII) has a three-port network with ports designated as X, Y, and Z, wherein the CCII includes a tunable feedback network. The tunable feedback network may be provided between at least two of the ports, e.g., ports Z and Y. The tunable feedback network may comprise a tunable RC (Resister- Capacitor) network which may be provided by solid-state components such as a MOS (Metal-Oxide Semiconductor) device or a MOS resistor (for the resistive element) and a varactor (for the capacitive element).
Immobilising isolated mycolic acid antigens of tuberculous mycobacterial origin or a synthetic analogue thereof on a screen-printed electrode by binding of the antigens to a self-assembled monolayer comprising a thiolated hydrophobic substance to produce immobilized mycolic acids antigens in the form of a mycolic acid antigen-containing self-assembled monolayer coating on a surface of the electrode.
The present invention relates to a method of detecting the presence of an antibody to an avian influenza hemagglutinin antigen in a sample from a subject, wherein the antibody binds to an epitope of an avian influenza hemagglutinin antigen, comprising the steps of cloning a nucleic acid encoding an avian influenza antigen into a vector, infiltrating a plant cell with the vector, recovering the antigen from the plant, contacting the sample with the antigen, and detecting the formation of an antibodyantigen complex, wherein the antibody-antigen complex comprises antibodies in the sample bound to the antigen and wherein the formation of an antibodyantigen complex confirms that the subject has been exposed to an avian influenza hemagglutinin antigen. The present invention also relates to a device for assaying the presence of an antibody to avian influenza hemagglutinin antigen in a sample from a subject.
The present invention relates to a method of detecting the presence of an antibody to an avian influenza hemagglutinin antigen in a sample from a subject, wherein the antibody binds to an epitope of an avian influenza hemagglutinin antigen, comprising the steps of cloning a nucleic acid encoding an avian influenza antigen into a vector, infiltrating a plant cell with the vector, recovering the antigen from the plant, contacting the sample with the antigen, and detecting the formation of an antibody–antigen complex, wherein the antibody-antigen complex comprises antibodies in the sample bound to the antigen and wherein the formation of an antibody–antigen complex confirms that the subject has been exposed to an avian influenza hemagglutinin antigen. The present invention also relates to a device for assaying the presence of an antibody to avian influenza hemagglutinin antigen in a sample from a subject.
The invention relates to an aircraft having a tailless fuselage. The fuselage has a body which includes a transverse trailing edge. The aircraft further includes a wing having two sides which protrude from opposite sides of the fuselage. The body typically has a fineness ratio of between 3 and 7. Each side of the wing has an inner section having a first dihedral angle and an outer section having a second dihedral angle, the second dihedral angle being less than the first dihedral angle. At least part of the outer section is typically swept back. The configuration of the aircraft provides it with improved flight efficiency.
2) and the zero crossing times. The method (400) includes determining the shaft Instantaneous Angular Position (IAP) between at least two zero crossing times, which determination comprises expressing the shaft IAP between at least two zero crossing times as a continuous, non-constant IAP mathematical function of time, with unknown function coefficients and calculating the unknown function coefficients of the IAP mathematical function.
1) and calculating (404) by a control module (212) a shaft Instantaneous Angular Position (IAP) as a function of time, and performing (410) an order tracking process which includes expressing (412) the measured proximity signal in the angular domain and resampling (414) the expressed proximity signal to render it equidistant in the angular domain. The method (400) includes performing (416) a pulse localisation process which includes filtering (418) the proximity signal yielding a complex-valued response, expressing (420) the complex-valued response in terms of a local amplitude and phase, and calculating (422) local phase shifts between each expressed signal and a reference signal.
The present invention relates to a transgenic plant having increased tolerance to an abiotic stress, including freeze stress, cold stress, heat stress, salt stress, drought stress, osmotic stress, water stress, oxidative stress and/or ionic, wherein the transgenic plant is transformed with a nucleic acid sequence encoding a WHy protein comprising SEQ ID NO:2. The invention further relates to a method for obtaining a transgenic plant having increased tolerance to an abiotic stress, comprising transforming a plant with a nucleic acid sequence encoding the WHy protein. The present invention also relates to vegetative tissue from the transgenic plant of the invention or produced according to the method of the invention and to seeds containing a nucleic acid sequence encoding the WHy protein.
The invention relates to a monitoring device 10 for monitoring exposure to sound. The monitoring device 10 includes an ear engaging member 12 which is shaped, sized and/or configured to engage and span an opening to an ear canal 16; a sound transmitter 18 which is configured to transmit sound via the ear engaging member 12 into the ear canal 16, when in use; and a sound sensor 20 which is configured to sense the sound transmitted into the ear canal 16 via the sound transmitter 18. The invention also relates to a monitoring system 100 which includes the monitoring device 10 and a processor 24 which is communicatively connected to the monitoring device 10. The processor 24 may be incorporated into a computing device, such as a computer or smart device 102.
The invention relates to an asthma warning/prevention system 10 and device 13. The system 10 includes a monitoring module 16 which is configured to receive measurement data of at least one environmental parameter measured by at least one environmental monitoring arrangement 12. The monitoring module 16 utilises the measurement data in order to determine whether the measured environmental parameter (a) exceeds a current upper trigger level for a particular person 113 and, if so, to adjust the current upper trigger level for that person 113, and/or (b) falls below a current lower trigger level for the particular person 113 and, if so, to adjust the current lower trigger level for the person 113. The system 10 may include a body monitoring arrangement 14 which is configured to measure one or more respiratory, physiological and/or biological parameters of the particular person 113.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A second-order all-pass network has at least three Second Generation Current Conveyors (CCIIs). A network input is connected or connectable to a Y port of a first CCII, a Z port of the first CCII is connected to a Y port of a second CCII, an X port of the first CCII is connected to a Y port of a third CCII, and a network output is connected or connectable, directly or indirectly, to a Z port of the second CCII. The second-order all-pass network also has a plurality of network elements. The X port of the first CCII is connected via a first network element to ground, the Z port of the first CCII is connected via a second network element to ground, an X port of the third CCII is connected via a third network element to ground, and an X port of the second CCII is connected via a fourth network element to ground.
A continuous process for the manufacture of celecoxib includes reacting a stream of a first solution of 4'-methylacetophenone in a first organic solvent and a stream of a second solution of ethyl trifluoroacetate in a second organic solvent in a first reactor in the presence of a base at a first reaction temperature of between 45°C and 90°C and at a first reaction pressure to form 4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione. The first reaction pressure prevents boiling inside the first reactor. A stream of a first reactor product from the first reactor is continuously withdrawn, the first reactor product including a solution of 4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione in the first organic solvent and the second organic solvent. A stream of the first reactor product and a stream of a third solution of (4-Sulfamoylphenyl)hydrazine hydrochloride in a third organic solvent are reacted in a second reactor at a second reaction temperature of between 80°C and 110°C and at a second reaction ressure to form celecoxib. The second reaction pressure prevents boiling inside the second reactor. A stream of a second reactor product is continuously withdrawn from the second reactor, the second reactor product including a solution of celecoxib in organic solvent.
C10G 1/08 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by destructive hydrogenation with moving catalysts
C10G 3/00 - Production of liquid hydrocarbon mixtures from oxygen-containing organic materials, e.g. fatty oils, fatty acids
C10G 1/10 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal from rubber or rubber waste
This invention relates to a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, a kit for performing the method, and furthermore to isolated nucleotide sequences being complementary to one or more mutations of the CFTR gene. According to a first aspect of the invention there is provided a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, including the steps of providing one or more nucleic acid sequences, fully complementary to one or more segments of the CFTR gene, wherein the one or more nucleic acid sequences correspond to the mutation to be identified; providing a biological sample of an individual to be tested for CF; isolating nucleic acids from the biological sample; and testing the biological sample for the presence of one or more of the nucleic acid sequences using a suitable detection method.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids
THE SOUTH AFRICAN NUCLEAR ENERGY CORPORATION LIMITED (South Africa)
UNIVERSITY OF PRETORIA (South Africa)
Inventor
Van Der Merwe, Daniel
Meyer, Helgard Pieter
Zeevaart, Jan Rijn
Suthiram, Janine
Sathekge, Mike Machaba
Ebenhan, Thomas
Abstract
This invention relates to a bioconjugate comprising a chelating agent capable of containing a radionuclide linked to Substance P for use as an imaging agent in a method for detection of increased availability of NK-1 receptors for diagnosing pain, especially chronic pain. The invention also relates to the treatment of pain.
A carbonaceous feed pyrolysis apparatus is provided including two or more hot particle fluidised beds, one of which contains a combustion zone, and one or more positive displacement apparatus for the transfer of hot particles beds. Also provided is a bio-oil production process including two or more fluidised beds, a first combustion zone carried out in one or more combustion fluidised beds in which a particulate material is fluidised and heated, and a second pyrolysis zone carried out in one or more pyrolysis fluidised beds in which hot particles heated in the combustion zone are used for pyrolysis of bio-mass, the combustion zone being operated at or about atmospheric pressure at a temperature of from 400° C. to 1100° C., and the pyrolysis zone being operated at a pressure of from atmospheric to 100 Barg at a temperature of from 400° C. to 900° C.
C10B 49/22 - Destructive distillation of solid carbonaceous materials by direct heating with heat-carrying agents including the partial combustion of the solid material to be treated with moving solid heat-carriers in divided form in dispersed form according to the "fluidised bed" technique
C10J 3/46 - Gasification of granular or pulverulent fuels in suspension
C10B 53/02 - Destructive distillation, specially adapted for particular solid raw materials or solid raw materials in special form of cellulose-containing material
B01J 8/18 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles
B01J 8/26 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles according to "fluidised-bed" technique with two or more fluidised beds, e.g. reactor and regeneration installations
B01J 8/00 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes
F23C 10/00 - Apparatus in which combustion takes place in a fluidised bed of fuel or other particles
F23C 10/01 - Apparatus in which combustion takes place in a fluidised bed of fuel or other particles in a fluidised bed of catalytic particles
F23G 5/027 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels including pretreatment pyrolising or gasifying
F23G 5/30 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels with combustion in a fluidised bed
C10B 57/02 - Multi-step carbonising or coking processes
C10B 57/06 - Other carbonising or coking processesFeatures of destructive distillation processes in general using charges of special composition containing additives
The invention is for a robot (10) which includes a base (12). A plurality of links (1A, 1B, 2, 3, 4 and 5) are connected in series. Six actuators are mounted on the base and drivingly connected, respectively, to the links (1A, 1B, 2, 3, 4 and 5) by means of drivetrains. At least some of the drivetrains include drive shafts and bevel gears whereby drive is transmitted from the actuator to the associated link.
B25J 9/10 - Programme-controlled manipulators characterised by positioning means for manipulator elements
B25J 9/12 - Programme-controlled manipulators characterised by positioning means for manipulator elements electric
B25J 9/04 - Programme-controlled manipulators characterised by movement of the arms, e.g. cartesian co-ordinate type by rotating at least one arm, excluding the head movement itself, e.g. cylindrical co-ordinate type or polar co-ordinate type
The invention relates to an aircraft having a tailless fuselage. The fuselage has a body which includes a transverse trailing edge. The aircraft further includes a wing having two sides which protrude from opposite sides of the fuselage. The body typically has a fineness ratio of between 3 and 7. Each side of the wing has an inner section having a first dihedral angle and an outer section having a second dihedral angle, the second dihedral angle being less than the first dihedral angle. At least part of the outer section is typically swept back. The configuration of the aircraft provides it with improved flight efficiency.
The invention relates to an aircraft having a tailless fuselage. The fuselage has a body which includes a transverse trailing edge. The aircraft further includes a wing having two sides which protrude from opposite sides of the fuselage. The body typically has a fineness ratio of between 3 and 7. Each side of the wing has an inner section having a first dihedral angle and an outer section having a second dihedral angle, the second dihedral angle being less than the first dihedral angle. At least part of the outer section is typically swept back. The configuration of the aircraft provides it with improved flight efficiency.
G. radlkoferi) plant, the extract including 5,7-dihidroxyflavone[(2S)-pinocembrin]; 2′,6′-dihydroxy-4′-methoxydihydrochalcone; 2′,4′,6′-trihydroxyhydrochalcone; 3,5,7-trihydroxyflavone and 4′,5′7-thhydroxyisoflavone.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin
A61K 36/77 - Sapindaceae (Soapberry family), e.g. lychee or soapberry
A method (400) of measuring rotor blade tip deflections of turbomachine rotor blades (R1, R2) during operation using Blade Tip Timing (BTT) includes measuring (402), by a proximity sensor (202), a proximity signal caused by a moving rotor blade R1, R2) and determining (412), by a control module (212), a Time-of-Arrival (ToA). The method (400) includes measuring a time that the shaft starts to rotate a measurable angular distance and a time the shaft has completed its rotation of the measurable distance and storing (406) timing data indicative of a plurality of ToA measurements of the rotor blade (R1, R2) and the zero crossing times. The method (400) includes determining the shaft Instantaneous Angular Position (IAP) between at least two zero crossing times, which determination comprises expressing the shaft IAP between at least two zero crossing times as a continuous, non-constant IAP mathematical function of time, with unknown function coefficients and calculating the unknown function coefficients of the IAP mathematical function.
A method (400) of determining blade tip deflection characteristics is applied to moving rotor blades (R1, R2) in a turbomachine (10) comprising a housing and rotor including a shaft with the rotor blades attached thereto and at least one proximity probe (202). The method (400) includes measuring ((402) a proximity signal caused by a presence of a proximate tip of a moving rotor blade (R1) and calculating (404) by a control module (212) a shaft Instantaneous Angular Position (IAP) as a function of time, and performing (410) an order tracking process which includes expressing (412) the measured proximity signal in the angular domain and resampling (414) the expressed proximity signal to render it equidistant in the angular domain. The method (400) includes performing (416) a pulse localisation process which includes filtering (418) the proximity signal yielding a complex-valued response, expressing (420) the complex-valued response in terms of a local amplitude and phase, and calculating (422) local phase shifts between each expressed signal and a reference signal.
A composite polymer fibre or filament includes a core of a polymer. The core includes a liquid active ingredient. A sheath surrounding the core is also of a polymer and acts to reduce the rate at which the liquid active ingredient is released from the core by establishing a negative concentration gradient of the liquid active ingredient from a core/sheath interface to an outer surface of the sheath. The filament can be incorporated in a multifilament yarn.
D01F 8/00 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof
D01F 8/06 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers with at least one polyolefin as constituent
A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
An insect repellent composition includes at least a first compound and a second, different compound. At least the first compound is an insect repellent. The first compound and the second compound are capable of together forming a negative pseudo-azeotrope with a vapour composition at ambient pressure and temperature in which the first compound is present in a sufficiently high concentration to provide an insect repellent effect. The insect repellent composition in some embodiments can also function as an insecticidal composition.
A01N 25/18 - Vapour or smoke emitting compositions with delayed or sustained release
A01N 37/02 - Saturated carboxylic acids or thio-analogues thereofDerivatives thereof
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 37/18 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N, e.g. carboxylic acid amides or imidesThio-analogues thereof
A01N 31/06 - Oxygen or sulfur directly attached to a cycloaliphatic ring system
A01N 47/16 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof the nitrogen atom being part of a heterocyclic ring
A process for producing a metal includes continuously rotating a horizontal cylindrical cathode which is partially immersed in a bath of liquid metal ion- containing electrolyte. A potential difference is applied between the cathode and an anode located in the bath, which allows, by means of an electrolysis reaction effected on the electrolyte by the applied potential difference, metal from the electrolyte to be deposited in particulate form onto an outer surface of the cathode. The particulate metal is continuously removed from the outer surface of the cathode.
A method of estimating vibration characteristics of moving rotor blades in a turbomachine comprising a housing and rotor including a shaft with the rotor blades attached thereto includes measuring, by at least one proximity sensor, a Time-of- Arrival (ToA) of a proximate tip of a moving rotor blade. The method includes manipulating, by a control module, timing data to determine a corresponding blade tip deflection at each measured ToA, expressing blade tip vibration behaviour as a Bayesian statistical model consisting of intermediate model parameters, wherein model coefficients in the statistical model are probabilistic quantities as opposed to conventional, deterministic quantities, and expressing, by the control module, the determined blade tip deflections as observed values in the statistical model. The method includes manipulating the intermediate model parameters in the statistical model using Bayesian linear regression or inference to estimate the intermediate model parameters and consequently the vibration behaviour of the rotor blade.
The invention relates to methods for preparing plant extracts having elastase inhibitory activity from a Myrsine africana plant and topical skin care compositions comprising such plant extracts. The invention further relates to plant extracts and compositions for use in cosmetic methods of inhibiting elastase activity in skin. The invention is also directed to the use of plant extracts from the plant Myrsine africana in methods of prevention or treatment of skin aging in a subject and methods of using the plant extracts from Myrsine africana.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 8/00 - Cosmetics or similar toiletry preparations
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (South Africa)
UNIVERSITY OF PRETORIA (South Africa)
Inventor
Suprakas, Ray, Sinha
Emmambux, Mohammad Naushad
Wokadala, Obiro
Abstract
The invention provides a method for the manufacture of amylose-lipid complexes The method includes the steps of pasting a mixture of starch and a fatty acid until after the second biphasic peak viscosity is reached, hydrolysing the starch with a hydrolysing enzyme, and dispersing the hydrolysed starch and working up of the residue. The amylose-lipid complexes has nano-structure dimensions and can be used a fat replacer in foodstuffs.
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
UNIVERSITY OF NEWCASTLE-UPON-TYNE (United Kingdom)
UNIVERSITY OF PRETORIA (South Africa)
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (Israel)
Inventor
Wright, Geraldine
Shafir, Sharoni
Nicolson, Sue
Stevenson, Phil
Abstract
The present invention relates to compositions, methods and products for providing nutrition to insects such as bees, e.g., honey bees. Certain embodiments of the present invention also relate to methods of providing nutrition to bees e.g., colonies of bees together with methods of preparing a composition for providing nutrition to bees.
This invention relates to a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, a kit for performing said method, and furthermore to isolated nucleotide sequences being complementary to one or more mutations of the CFTR gene. According to a first aspect of the invention there is provided a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, including the steps of providing one or more nucleic acid sequences, fully complementary to one or more segments of the CFTR gene, wherein the said one or more nucleic acid sequences correspond to the mutation to be identified; providing a biological sample of an individual to be tested for CF; isolating nucleic acids from the biological sample; and testing the biological sample for the presence of one or more of the nucleic acid sequences using a suitable detection method.
The invention provides a method of diagnosing tuberculosis by using a novel antibody biomarker capturing vehicle, activating a screen-printed electrode using chemical and mechanical polishing, and immobilising mycolic acid antigen biomarkers on the activated electrode. The novel antibody biomarker capturing vehicle is produced by introducing isolated mycolic acid antigens of tuberculous mycobacterial origin onto an outer surface of a nanoparticle such that the mycolic acid antigens are presented as antibody biomarker capturing agents. The solvent resistant screen-printed electrode is activated by both chemically and mechanically polishing the electrode. The mycolic acid antigens are immobilised on the activated electrode by incubating the activated electrode with a mycolic acid-dimethylformamide solution to allow mycolic acid antigens to adsorb onto the activated electrode.
The invention provides a catalyst system and method for the deoxygenation of hydrocarbons, such as bio-oil, using a sulphide-sulfate or an oxide-carbonate (LDH) system. The invention extends to a pyrolysis process of a carbonaceous bio-mass wherein a first combustion zone is carried out in one or more combustion fluidised beds in which a particulate material including chemically looping deoxygenation catalyst particles is fluidised and heated, and a second pyrolysis zone carried out in one or more pyrolysis fluidised beds in which the hot particles, including the catalyst particles, heated in the combustion zone are used for pyrolysis of the bio-mass, said combustion zone being operated at a temperature of from 250 °C to 1100°C, typically around 900 °C, and the pyrolysis zone being operated at a temperature of from 250 °C to 900 °C, typically 450 °C to 600°C, said catalyst particles being oxygenated in the pyrolysis zone in the presence of oxygenates in the pyrolysis oil and regenerated in the combustion zone either by calcining to drive off the carbon oxides, such as CO2, or by reduction to its form which is active for deoxygenation of the pyrolysis oil.
C10G 1/08 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by destructive hydrogenation with moving catalysts
C10G 1/10 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal from rubber or rubber waste
C10G 3/00 - Production of liquid hydrocarbon mixtures from oxygen-containing organic materials, e.g. fatty oils, fatty acids
The invention provides a catalyst system and method for the deoxygenation of hydrocarbons, such as bio-oil, using a sulphide-sulfate or an oxide-carbonate (LDH) system. The invention extends to a pyrolysis process of a carbonaceous bio-mass wherein a first combustion zone is carried out in one or more combustion fluidised beds in which a particulate material including chemically looping deoxygenation catalyst particles is fluidised and heated, and a second pyrolysis zone carried out in one or more pyrolysis fluidised beds in which the hot particles, including the catalyst particles, heated in the combustion zone are used for pyrolysis of the bio-mass, said combustion zone being operated at a temperature of from 250 °C to 1100°C, typically around 900 °C, and the pyrolysis zone being operated at a temperature of from 250 °C to 900 °C, typically 450 °C to 600°C, said catalyst particles being oxygenated in the pyrolysis zone in the presence of oxygenates in the pyrolysis oil and regenerated in the combustion zone either by calcining to drive off the carbon oxides, such as CO2, or by reduction to its form which is active for deoxygenation of the pyrolysis oil.
C10G 1/08 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by destructive hydrogenation with moving catalysts
C10G 1/10 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal from rubber or rubber waste
C10G 3/00 - Production of liquid hydrocarbon mixtures from oxygen-containing organic materials, e.g. fatty oils, fatty acids
79.
Ptaeroxylon obliquum nand compounds having antimicrobial and antihelminthic activity
This invention relates to an antimicrobial and antihelminthic agent comprising a compound of formula (I), to a process for extracting the antimicrobial and/or antihelminthic agent from plant material, to a composition containing the antimicrobial and/or antihelminthic agent, and to a plant extract containing the antimicrobial and/or antihelminthic agent.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Helichrysum odoratissimum for use in the prevention of and treatment of skin cancer. The invention also provides for pharmaceutical compositions containing the extract and to the use of medicaments containing the extract.
A61K 36/28 - Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 31/231 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
Mycolic acid antigen containing liposomes, and an electrode immobilised antigens of tuberculous mycobacterial origin are produced. A diagnostic sample from a human suspected of having tuberculosis is diluted and divided into first and second samples. A control sample comprising the first sample and a redox probe is exposed to the liposomes. A test sample comprising the second sample and a redox probe is exposed to liposomes not containing mycolic acid antigens. The control sample is contacted with the immobilised antigens to allow antibodies therein to bind to the antigens. The test sample is contacted with the immobilised antigens to allow any antibodies therein to bind to the antigens. The degree of binding in the samples is compared by electrochemical impedance spectroscopy. Any observed lesser binding by the control sample is an indicator of antibodies to the antigens in the diagnostic sample, indicating tuberculosis in the human.
The invention provides a method for detecting a genetic polymorphism associated with susceptibility, or resistance of an ectoparasite to an acaricide, the method comprising the step of screening a DNA sample from the ectoparasite for the presence of one or more markers in the octopamine/tyramine receptor gene.
The invention provides an apparatus which consists of two fluidized beds 1 and 2 separated by a vertical divides' 5. A positive displacement device such as an auger 3 moves the bed material from the reduction side to the combustion side of the device below the fluidization zone. The height of the two fluidized beds is equalized by movement of the bed material through a hole 4 In the vertical divider, from the high temperature side 1 (zone 1) to the tow temperature side 2 (zone 2). The bed material that moves through the hole 4 provides energy to drive reactions that may occur on the reduction side. Energy may also be provided to zone 2 by means of conductive and radiative heat transfer through the dividing wall 5. Energy is provided to zone 1 by means of an exothermic reaction, typically combustion of a fuel 13 using air 12.
C10B 49/22 - Destructive distillation of solid carbonaceous materials by direct heating with heat-carrying agents including the partial combustion of the solid material to be treated with moving solid heat-carriers in divided form in dispersed form according to the "fluidised bed" technique
C10J 3/46 - Gasification of granular or pulverulent fuels in suspension
C10B 53/02 - Destructive distillation, specially adapted for particular solid raw materials or solid raw materials in special form of cellulose-containing material
B01J 8/18 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles
B01J 8/26 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles according to "fluidised-bed" technique with two or more fluidised beds, e.g. reactor and regeneration installations
F23C 10/00 - Apparatus in which combustion takes place in a fluidised bed of fuel or other particles
F23G 5/02 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels including pretreatment
C10B 57/02 - Multi-step carbonising or coking processes
C10B 57/06 - Other carbonising or coking processesFeatures of destructive distillation processes in general using charges of special composition containing additives
B01J 8/00 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes
F23C 10/01 - Apparatus in which combustion takes place in a fluidised bed of fuel or other particles in a fluidised bed of catalytic particles
F23G 5/027 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels including pretreatment pyrolising or gasifying
F23G 5/30 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels with combustion in a fluidised bed
84.
METHODS FOR DETECTING A GENETIC POLYMORPHISM IN IMPALA
The invention relates to a method for detecting a genetic polymorphism associated with a black phenotype of impala. The method comprising the step of screening a genomic material sample from an impala for the presence of at least one polymorphism in the Agouti Signalling Peptide (ASIP) gene.
An orthogonal frequency division multiplexing (OFDM) modulation method, which includes phase modulating both the real and imaginary components of an OFDM signal.
This invention relates to a biocontrol composition comprising at least one isolated strain selected from the group consisting of Bacillus megaterium strain A-07, Paenibacillus barcinonensis strain A-10, Pseudomonas fluoresceins strainN-04, Bacillus cereus strain T-1 1, Lysinibacillus sphaericus strain T-19, Paenibacillus alvei strain T-22 and Paenibacillus alvei strain T29 which have have been shown to be effective plant growth enhancers and biocontrol agents of plant disease in greenhouse and in field trials. The invention further relates to procedures for identifying effective Plant Growth Promoting Rhizobacterial strains, isolating these strains, growing them in pure culture, and screening the isolates for efficacy as plant growth enhancers and biocontrol agents of plant pathogens by means of specific assays.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
C05F 11/08 - Organic fertilisers containing added bacterial cultures, mycelia or the like
A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
Methods and compositions for identifying maize plants that have newly conferred tolerance or enhanced tolerance to, or are susceptible to, Gray Leaf Spot (GLS) are provided. The methods use molecular genetic markers to identify, select and/or construct tolerant plants or identify and counter-select susceptible plants. Maize plants that display newly conferred tolerance or enhanced tolerance to GLS that are generated by the methods are also a feature of the invention.
Recombinant nucleic acid molecules are provided that form hair pin structures and can be used to down-regulate gene expression. For example, a nucleic acid molecule can comprise a flanking and lower stem loop sequence from a mir-16 gene; an antisense target sequence; a mir-30 loop sequence; a complement of the anti-sense target sequence; and a lower stem loop complementary to the mir-16 sequence. Methods for down regulating gene expression in a cell using such recombinant nucleic acid molecules are also provided.
The invention relates to an improved alkaline-activated slag (AAS) composition which includes a source of slag and a source of an alkali metal carbonate comprising 0.5 to 6.0 in the metal oxide equivalent (i.e. Na20 for Na2C03) weight % of the source of slag and a source of an amorphous polymorph of silicon dioxide comprising 0.5 to 10.0 weight % of the source of slag and a source of an alkaline metal hydroxide comprising 0.5 - 10.0 weight % of the source of slag. The invention further relates to a process for the preparation of a dry mixed ready-to-use alkaline-activated slag (AAS) composition.
C04B 7/153 - Mixtures thereof with other inorganic cementitious materials or other activators
C04B 7/17 - Mixtures thereof with other inorganic cementitious materials or other activators with calcium oxide containing activators
90.
Liposomal composition comprising a sterol-modified lipid and a purified mycobacterial lipid cell wall component and its use in the diagnosis of tuberculosis
The present invention relates to shoot extracts from Euclea natalensis for use in modulating immune responses in a subject and/or providing hepatoprotection in a subject. The invention also provides for pharmaceutical compositions contain the extract and to the use of medicaments contain the extract.
The present invention relates to extracts from Helichrysum odoratissimum for use in the prevention of and treatment of skin cancer. The invention also provides for pharmaceutical compositions containing the extract and to the use of medicaments containing the extract.
The invention provides an audiometry system for performing a mobile hearing screening, and a method for performing said screening. The system comprises a mobile device for transmitting a plurality of different predetermined signals representing predetermined sounds of different frequency and intensity; at least one set of earphones provided with a receiver for receiving the signals, the earphones being responsive to the signals for emitting said predetermined sounds in accordance with the signals; and an interface programmed to determine and record the response of a user of the earphones to the emission of the respective sounds by the earphones in response to the signals.
The invention relates to a method of determining interaction between at least three agents and the probability of them having an inhibitory effect. The method includes representing outcomes of synergistic tests as at least one set of binary matrices, each set including at least a first and a second matrix, first matrices each representing binary outcomes of different concentration combinations of two agents, and second matrices each representing outcomes of the different concentration combinations of the two agents with an additional fixed concentration of a third agent, the number of sets of matrices depending on the number of agents for which synergistic activity is to be determined. The method further includes feeding the binary matrices into a qualitative response model and to generate a prediction model. The prediction model represents approximated outcomes of the synergistic activity between the at least three agents.
C12Q 1/18 - Testing for antimicrobial activity of a material
G06F 19/10 - Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology (in silico methods of screening virtual chemical libraries C40B 30/02;in silico or mathematical methods of creating virtual chemical libraries C40B 50/02)
An apparatus for conducting an endothermic reaction process has two fluidised beds, each having a fluidised bed zone, that are separated by an apertured vertical divider 5. One of the fluidised bed zones being on a reduction side and another of the fluidised bed zones being on a combustion side. A positive displacement device moves the bed material from the reduction side to the combustion side of the apparatus below the fluidised bed zones. The height of the two fluidised beds is equalised by movement of the bed material through the apertures in the vertical divider, from the high temperature side (zone 1) to the low temperature side (zone 2). The bed material that moves through the apertures provides energy to drive reactions that may occur on the reduction side.
B01J 8/24 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles according to "fluidised-bed" technique
The invention provides an apparatus which consists of two fluidised beds 1 and 2 separated by a vertical divides' 5. A positive displacement device such as an auger 3 moves the bed material from the reduction side to the combustion side of the device below the fluidisation zone. The height of the two fluidised beds is equalised by movement of the bed material through a hole 4 In the vertical divider, from the high temperature side 1 (zone 1) to the tow temperature side 2 (zone 2). The bed material that moves through the hole 4 provides energy to drive reactions that may occur on the reduction side. Energy may also be provided to zone 2 by means of conductive and radiative heat transfer through the dividing wall 5. Energy is provided to zone 1 by means of an exothermic reaction, typically combustion of a fuel 13 using air 12.
C10B 49/22 - Destructive distillation of solid carbonaceous materials by direct heating with heat-carrying agents including the partial combustion of the solid material to be treated with moving solid heat-carriers in divided form in dispersed form according to the "fluidised bed" technique
C10B 53/02 - Destructive distillation, specially adapted for particular solid raw materials or solid raw materials in special form of cellulose-containing material
B01J 8/26 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles according to "fluidised-bed" technique with two or more fluidised beds, e.g. reactor and regeneration installations
F23C 10/00 - Apparatus in which combustion takes place in a fluidised bed of fuel or other particles
Mycolic acid antigen containing liposomes, and an electrode immobilised antigens of tuberculous mycobacterial origin are produced. A diagnostic sample from a human suspected of having tuberculosis is diluted and divided into first and second samples. A control sample comprising the first sample and a redox probe is exposed to the liposomes. A test sample comprising the second sample and a redox probe is exposed to liposomes not containing mycolic acid antigens. The control sample is contacted with the immobilised antigens to allow antibodies therein to bind to the antigens. The test sample is contacted with the immobilised antigens to allow any antibodies therein to bind to the antigens. The degree of binding in the samples is compared by electrochemical impedance spectroscopy. Any observed lesser binding by the control sample is an indicator of antibodies to the antigens in the diagnostic sample, indicating tuberculosis in the human.
This invention relates to an antimicrobial and antihelminthic agent comprising a compound of formula (I), to a process for extracting the antimicrobial and/or antihelminthic agent from plant material, to a composition containing the antimicrobial and/or antihelminthic agent, and to a plant extract containing the antimicrobial and/or antihelminthic agent.
Methods for selecting transgenic cells comprising two or more drug resistance genes with a combination of cytotoxic drugs (e.g., trimetrexate (TMTX) and hydroxyurea (HU)). Such selection can be completed in vitro or in vivo. Transgenic cells and vectors comprising combinations of resistance genes are also provided. Transgenic cells of the embodiments can be used as cell based therapeutics, such as for treatment of HIV infection.
The invention relates to oral care. In particular the invention relates to an oral care composition for inhibiting the growth of potentially pathogenic oral microorganisms, said composition comprising an extract of Heteropyxis natalensis. The invention further relates to an oral care composition which includes Heteropyxis natalensis in combination with other essential oils and plant extracts.
A61Q 11/00 - Preparations for care of the teeth, of the oral cavity or of dentures, e.g. dentifrices or toothpastesMouth rinses
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
patents
