Abstract

A vital signs monitoring system configured to estimate the heart rates of two or more subjects using a plurality of subcarriers of a radio frequency (RF) signal.

IPC Classes  ?

• A61B 5/0507 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves using microwaves or terahertz waves
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/08 - Measuring devices for evaluating the respiratory organs
• A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb

Abstract

An absorber for absorbing electromagnetic radiation including a first layer with hydrogenated carbon, and a second layer with carbon, and the first layer is less absorbing than the second layer.

IPC Classes  ?

• H10N 10/855 - Thermoelectric active materials comprising inorganic compositions comprising compounds containing boron, carbon, oxygen or nitrogen
• H10N 10/851 - Thermoelectric active materials comprising inorganic compositions
• H10N 10/01 - Manufacture or treatment
• G01J 5/08 - Optical arrangements
• G01J 5/12 - Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors using thermoelectric elements, e.g. thermocouples

Abstract

Described herein are pharmaceutical compositions and contact lens solutions comprising an Acanthamoeba encystation inhibitor such as a cationic quaternary ammonium compound and a physiologically or pharmaceutically acceptable carrier or excipient, optionally in combination with an Acanthamoeba cytotoxic agent such as an alkylphosphocholine. Such compositions are suitable for use in the treatment of Acanthamoeba infection or the prevention or treatment of Acanthamoeba keratitis.

IPC Classes  ?

• A61K 31/661 - Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion
• A61P 33/04 - Amoebicides

Abstract

An absorber for absorbing electromagnetic radiation comprising a first layer comprising hydrogenated carbon, and a second layer comprising carbon, wherein the first layer is less absorbing than the second layer.

IPC Classes  ?

• G01J 5/08 - Optical arrangements
• G01J 5/12 - Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors using thermoelectric elements, e.g. thermocouples

Abstract

An optical sensor for multispectral analysis of a fluid sample comprises at least one light source, at least one interference filter, and a plurality of light detectors arranged such that light emitted by the at least one light source is incident on the at least one interference filter. There is a spatial variation in the intensity of light incident on the said at least one interference filter.

IPC Classes  ?

• G01J 3/10 - Arrangements of light sources specially adapted for spectrometry or colorimetry
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01J 3/12 - Generating the spectrumMonochromators
• G01J 3/42 - Absorption spectrometryDouble-beam spectrometryFlicker spectrometryReflection spectrometry
• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
• G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water

Abstract

Described herein are pharmaceutical compositions and contact lens solutions comprising an Acanthamoeba encystation inhibitor such as a cationic quaternary ammonium compound and a physiologically or pharmaceutically acceptable carrier or excipient, optionally in combination with an Acanthamoeba cytotoxic agent such as an alkylphosphocholine. Such compositions are suitable for use in the treatment of Acanthamoeba infection or the prevention or treatment of Acanthamoeba keratitis.

IPC Classes  ?

• A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline
• A61K 31/6615 - Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
• A61P 33/04 - Amoebicides
• C11D 1/00 - Detergent compositions based essentially on surface-active compoundsUse of these compounds as a detergent
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

Apparatus for depositing germanium and carbon onto one or more substrates comprises a vacuum chamber, at least first and second magnetron sputtering devices and at least one movable mount for supporting the one or more substrates within the vacuum chamber. The first magnetron sputtering device is configured to sputter germanium towards the at least one mount from a first sputtering target comprising germanium, thereby defining a germanium sputtering zone within the vacuum chamber. The second magnetron sputtering device is configured to sputter carbon towards the at least one mount from a second sputtering target comprising carbon, thereby defining a carbon sputtering zone within the vacuum chamber. The at least one mount and the at least first and second magnetron sputtering devices are arranged such that, when each substrate is moved through the germanium sputtering zone on the at least one movable mount, germanium is deposited on the said substrate, and when each substrate is moved through the carbon sputtering zone on the at least one movable mount, carbon is deposited on the said substrate.

IPC Classes  ?

• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering
• C23C 14/58 - After-treatment
• C23C 14/04 - Coating on selected surface areas, e.g. using masks
• C23C 14/34 - Sputtering
• C23C 14/50 - Substrate holders
• C23C 14/54 - Controlling or regulating the coating process
• G02B 5/20 - Filters
• G02B 5/28 - Interference filters
• H01J 37/34 - Gas-filled discharge tubes operating with cathodic sputtering

Abstract

An optical sensor for multispectral analysis of a fluid sample comprises at least one light source, at least one interference filter, and a plurality of light detectors arranged such that light emitted by the at least one light source is incident on the at least one interference filter. There is a spatial variation in the intensity of light incident on the said at least one interference filter.

IPC Classes  ?

• G01J 3/10 - Arrangements of light sources specially adapted for spectrometry or colorimetry
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01J 3/12 - Generating the spectrumMonochromators
• G01J 3/42 - Absorption spectrometryDouble-beam spectrometryFlicker spectrometryReflection spectrometry
• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
• G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water

Abstract

Apparatus for depositing one or more variable interference filters onto one or more substrates comprises a vacuum chamber, at least one magnetron sputtering device and at least one movable mount for supporting the one or more substrates within the vacuum chamber. The at least one magnetron sputtering device is configured to sputter material from a sputtering target towards in the mount, thereby defining a sputtering zone within the vacuum chamber. At least one static sputtering mask is located between the sputtering target and the mount. The at least one static sputtering mask is configured such that, when each substrate is moved through the sputtering zone on the at least one movable mount, a layer of material having a non-uniform thickness is deposited on each said substrate.

IPC Classes  ?

• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering
• C03C 17/34 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
• C23C 14/04 - Coating on selected surface areas, e.g. using masks
• G02B 5/28 - Interference filters
• H01J 37/34 - Gas-filled discharge tubes operating with cathodic sputtering
• C23C 14/54 - Controlling or regulating the coating process

Abstract

Apparatus for depositing germanium and carbon onto one or more substrates comprises a vacuum chamber, at least first and second magnetron sputtering devices and at least one movable mount for supporting the one or more substrates within the vacuum chamber. The first magnetron sputtering device is configured to sputter germanium towards the at least one mount from a first sputtering target comprising germanium, thereby defining a germanium sputtering zone within the vacuum chamber. The second magnetron sputtering device is configured to sputter carbon towards the at least one mount from a second sputtering target comprising carbon, thereby defining a carbon sputtering zone within the vacuum chamber. The at least one mount and the at least first and second magnetron sputtering devices are arranged such that, when each substrate is moved through the germanium sputtering zone on the at least one movable mount, germanium is deposited on the said substrate, and when each substrate is moved through the carbon sputtering zone on the at least one movable mount, carbon is deposited on the said substrate.

IPC Classes  ?

• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
• C23C 14/34 - Sputtering
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering
• C23C 14/50 - Substrate holders
• C23C 14/54 - Controlling or regulating the coating process
• C23C 14/56 - Apparatus specially adapted for continuous coatingArrangements for maintaining the vacuum, e.g. vacuum locks
• C23C 14/58 - After-treatment
• G02B 5/20 - Filters

Abstract

A mechanical bioreactor for transferring vibrations to cell cultures for the purpose of stimulating various biological processes across a relatively large (relative to the amplitude of the vibrations) sample receiving surface. This bioreactor allows multiple samples to receive identical stimulation, which may enable the process to be significantly scaled up. The invention may be particularly applicable to nanoscale vibration amplitudes, where it is non-trivial to design a device that performs this function, because many materials exhibit natural deformation on a scale that would mask or inhibit transfer of nanoscale vibration energy.

IPC Classes  ?

• C12M 1/42 - Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12M 1/32 - Inoculator or sampler multiple field or continuous type
• C12N 13/00 - Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means

Abstract

An optical sensor for multispectral analysis of a fluid sample comprises at least one light source, at least one interference filter, and a plurality of light detectors arranged such that light emitted by the at least one light source is incident on the at least one interference filter. There is a spatial variation in the intensity of light incident on the said at least one interference filter.

IPC Classes  ?

• G01J 3/10 - Arrangements of light sources specially adapted for spectrometry or colorimetry
• G01J 3/42 - Absorption spectrometryDouble-beam spectrometryFlicker spectrometryReflection spectrometry

Abstract

Apparatus for depositing one or more variable interference filters onto one or more substrates comprises a vacuum chamber, at least one magnetron sputtering device and at least one movable mount for supporting the one or more substrates within the vacuum chamber. The at least one magnetron sputtering device is configured to sputter material from a sputtering target towards the mount, thereby defining a sputtering zone within the vacuum chamber. At least one static sputtering mask is located between the sputtering target and the mount. The at least one static sputtering mask is configured such that, when each substrate is moved through the sputtering zone on the at least one movable mount, a layer of material having a non-uniform thickness is deposited on each said substrate.

IPC Classes  ?

• C23C 14/04 - Coating on selected surface areas, e.g. using masks
• C03C 17/00 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering
• C23C 14/58 - After-treatment
• C23C 14/54 - Controlling or regulating the coating process
• C23C 14/56 - Apparatus specially adapted for continuous coatingArrangements for maintaining the vacuum, e.g. vacuum locks
• G02B 5/28 - Interference filters
• C23C 14/00 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
• C23C 14/08 - Oxides
• C23C 14/10 - Glass or silica
• H01J 37/34 - Gas-filled discharge tubes operating with cathodic sputtering
• G02B 1/10 - Optical coatings produced by application to, or surface treatment of, optical elements

Abstract

A mechanical bioreactor for transferring vibrations to cell cultures for the purpose of stimulating various biological processes across a relatively large (relative to the amplitude of the vibrations) sample receiving surface. This bioreactor allows multiple samples to receive identical stimulation, which may enable the process to be significantly scaled up. The invention may be particular applicable to nanoscale vibration amplitudes, where it is non- trivial to design a device that performs this function, because many materials exhibit natural deformation on a scale that would mask or inhibit transfer of nanoscale vibration energy.

IPC Classes  ?

• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• C12M 1/32 - Inoculator or sampler multiple field or continuous type
• C12M 1/42 - Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters

Abstract

We disclose the preparation of a serum free differentiation medium comprising cell free human astrocyte conditioned medium and including a cell culture and method for the differentiation of neural stem cells/neural progenitor cells into differentiated neurones and their use in the repair of diseased or damage neural tissue and in drug screening.

IPC Classes  ?

• C12N 5/079 - Neural cells

Abstract

Use of a compound in the control of growth of at least one organism of the order of Amoebida, wherein said compound is capable of modulating the histidine biosynthesis pathway, and / or the methionine biosynthesis pathway and/or a pathway branching from the histidine biosynthesis pathway and / or methionine biosynthesis pathway in said organism.

IPC Classes  ?

• C12N 9/88 - Lyases (4.)
• C12N 1/10 - ProtozoaCulture media therefor
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• A61K 31/4196 - 1,2,4-Triazoles
• A61K 35/68 - Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
• A61L 12/00 - Methods or apparatus for disinfecting or sterilising contact lensesAccessories therefor
• C12R 1/90 - Protozoa

Abstract

A device comprising a solid-state actuator (100), means for inputting an acoustic signal to the actuator (104) and means for measuring the resultant signal (104). The measured acoustic signal can be used to determine the extension of the solid-state actuator.

IPC Classes  ?

• G01B 17/04 - Measuring arrangements characterised by the use of infrasonic, sonic, or ultrasonic vibrations for measuring the deformation in a solid, e.g. by vibrating string