Disclosed herein are methods and systems for training artificial intelligence (AI) models. A central server may train an AI model by outputting, onto an electronic device operated by a user, results of execution of the AI model; monitoring the electronic device to identify a set of interactions between the user and the electronic device while the electronic device is outputting the results; generating a first training dataset corresponding to the user's interactions with the electronic device, the first training dataset corresponding to a frequency of correction of results; generating a second training dataset corresponding to the user's input to a prompt requesting the user to input a numerical value associated with an accuracy of the results; and training the AI model using the first and second training datasets.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
2.
PATIENT MARKING AND POSITIONING IN A RADIATION THERAPY SYSTEM
An example method for a radiation therapy system that includes a movable couch to perform radiation therapy has been disclosed. One method includes based on the X-ray images of an anatomical region of the patient that includes a target volume, reconstructing a digital volume of the anatomical region and based on a user input indicating a location of a patient origin in the digital volume, determining one or more shift values for repositioning the patient origin at an isocenter of the radiation therapy system with respect to a coordinate system. The method also includes obtaining a treatment plan that is based on the location of the patient origin and is associated with the target volume, based on the treatment plan, repositioning the movable couch so that the patient origin is disposed at the isocenter, and while the patient origin is disposed at the isocenter, directing a treatment beam to the patient origin in accordance with the treatment plan associated with the target volume.
A method includes obtaining image data of the heart of the patient, obtaining image data of a torso of the patient, obtaining positions of electrodes at the torso, obtaining a measured ECG signal measured at the patient using the electrodes, parameterizing of a model for estimating electrical potentials on the skin of the torso of the patient depending on cardiac activity, determining multiple simulated ECG signals for multiple activation patterns using the model, and determining the cardiac activation area of the heart based on comparing the multiple simulated ECG signals with the measured ECG signal.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/318 - Heart-related electrical modalities, e.g. electrocardiography [ECG]
A61B 5/349 - Detecting specific parameters of the electrocardiograph cycle
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
5.
METHODS AND APPARATUS FOR RADIOABLATION TREATMENT AREA TARGETING AND GUIDANCE
Systems and methods for target area recommendation and guidance during radioablation treatment planning are disclosed. In some examples, a computing device receives (702) image data from one or more modalities for a patient. The computing device determines (708) a recommended target area for treatment based on the image data, and determines one or more corresponding segments of a segment model based on the recommended target area. Further, the computing device displays the segment model identifying the determined one or more segments, and receives (710) input data modifying the determined one or more segments. Based on the input data, the computing device updates (716) the one or more segments, and generates target definition data characterizing the updated one or more segments. The computing device transmits the target definition data for treating the patient.
Systems (100) and methods (700, 800, 900) for target area recommendation and guidance during radioablation treatment planning are disclosed. In some examples. a computing device (104) receives image data (103) from one or more modalities for a patient. The computing device (104) determines a recommended target area for treatment based on the image data (103), and determines one or more corresponding segments of a segment model based on the recommended target area. Further, the computing device (104) displays the segment model identifying the determined one or more segments. and receives input data modifying the determined one or more segments. Based on the input data, the computing device (104) updates the one or more segments, and generates target definition data characterizing the updated one or more segments. The computing device (104) transmits the target definition data for treating the patient.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
7.
Display screen with graphical user interface for radiotherapy machine
Systems, devices and methods for internal dose adapted automated external radiation beam therapy, and systems and methods for an automated adaptive workflow to automatically generate a radiation treatment plan based on the internal dose and adapt the treatment plan to a current treatment session using a set of directives.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
16 - Paper, cardboard and goods made from these materials
Goods & Services
Three-dimensional models of radiotherapy equipment for playing purposes Three-dimensional models of radiotherapy equipment for teaching purposes; Three-dimensional models of radiotherapy equipment for demonstration purposes
10.
MICROWAVE NETWORKS, WAVEGUIDES, MIXING CARTS, METHODS OF SUPPLYING GAS, AND GAS MANAGEMENT SYSTEMS FOR RADIATION THERAPY MACHINES
A microwave network for a radiation therapy machine having a microwave source and a linear accelerator, includes a waveguide configured to connect between the microwave source and the linear accelerator. The waveguide contains at least one of a first gas or a second gas, the first gas being 2,3,3,3-tetrafluoro-2-(trifluoromethyl) propanenitrile and the second gas being 1,1,1,3,4,4,4-heptafluoro-3-(trifluoromethyl)-2-butanone.
A combination ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of the conduit in the shell and at least one heat transfer element in thermal communication with the heater and the shell.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
12.
COMBINATION PROBE FOR CRYOABLATION AND THERMAL ABLATION WITH EXTERNAL HEATER
An ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of an outer surface of the shell that is configured to heat the probe to perform thermal ablation.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
13.
COMBINATION PROBE FOR CRYOABLATION AND THERMAL ABLATION AND RELATED METHODS
A combination ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of the conduit in the shell and at least one heat transfer element in thermal communication with the heater and the shell.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/08 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
14.
COMBINATION PROBE FOR CRYOABLATION AND THERMAL ABLATION WITH EXTERNAL HEATER
An ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of an outer surface of the shell that is configured to heat the probe to perform thermal ablation.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/08 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A radiotherapy system includes an X-ray target configured to convert an incident electron beam into a therapeutic X-ray beam, a purging magnet configured to redirect unwanted particles emitted from the X-ray target away from the therapeutic X-ray beam, and a particle collector configured to absorb the unwanted particles subsequent to redirection by the purging magnet. The particle collector may be configured to dissipate at least 50% of the energy of the incident electron beam.
H01J 35/10 - Rotary anodesArrangements for rotating anodesCooling rotary anodes
H01J 35/14 - Arrangements for concentrating, focusing, or directing the cathode ray
H01J 35/22 - X-ray tubes specially designed for passing a very high current for a very short time, e.g. for flash operation
H01J 35/30 - Tubes wherein the point of impact of the cathode ray on the anode or anticathode is movable relative to the surface thereof by deflection of the cathode ray
H05G 2/00 - Apparatus or processes specially adapted for producing X-rays, not involving X-ray tubes, e.g. involving generation of a plasma
Siemens Healthineers International AG. (Switzerland)
Inventor
Smith, Christel
Zankowski, Corey
Timmer, Jan Hein
Kaissl, Wolfgang
Khuntia, Deepak
Abel, Eric
Star-Lack, Josh
Noel, Camille
Abstract
In various embodiments, a radiation therapy method can include loading a planning image of a target in a human. In addition, the position of the target can be monitored. A computation can be made of an occurrence of substantial alignment between the position of the target and the target of the planning image. Furthermore, after the computing, a beam of radiation is triggered to deliver a dosage to the target in a short period of time (e.g., less than a second).
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
17.
SYSTEM AND METHOD TO MEASURE TEMPERATURE AND GENERATE HEAT USING A RESISTIVE MATERIAL
A heating system (100) includes a power supply (DC) that applies a first voltage to a sense resistor (RS) in series with a resistive heating material (RH) during a first time period; and a controller (CON) that determines a temperature of the resistive heating material (RH) based on a current through the sense resistor (RS) and a second voltage across the resistive heating material (RH) during the first time period. Additionally, the controller (CON) commands the power supply to provide a third voltage to the resistive heating material (RH) during a second time period, and the third voltage is based on the temperature of the resistive heating material (RH).
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
18.
SYSTEM AND METHOD TO MEASURE TEMPERATURE AND GENERATE HEAT USING A RESISTIVE MATERIAL
A heating system includes a power supply that applies a first voltage to a sense resistor in series with a resistive heating material during a first time period; and a controller that determines a temperature of the resistive heating material based on a current through the sense resistor and a second voltage across the resistive heating material during the first time period. Additionally, the controller commands the power supply to provide a third voltage to the resistive heating material during a second time period, and the third voltage is based on the temperature of the resistive heating material.
G05D 23/24 - Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature the sensing element having a resistance varying with temperature, e.g. thermistor
G01K 3/00 - Thermometers giving results other than momentary value of temperature
G01K 7/16 - Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat using resistive elements
H05B 3/06 - Heater elements structurally combined with coupling elements or with holders
19.
Electronic device display screen with graphical user interface for radiotherapy machine parameter tracking
A guidance indicator includes an indicator platform having an indicator surface and a mounting portion connected to the indicator platform and supporting the indicator surface in a predetermined orientation relative to a needle of an ablation probe. The mounting portion is adapted to removably attach to a complimentary attachment post of the ablation probe.
A radiation system includes a modulator and at least one voltage regulator. The modulator is configured to output a voltage for operation of a magnetron and an electron gun of the radiation system. The at least one voltage regulator circuit is electrically connected between the modulator and at least one of the magnetron or the electron gun, and configured to control a magnitude of the voltage output from the modulator for operation of the magnetron and the electron gun.
H02M 3/07 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using resistors or capacitors, e.g. potential divider using capacitors charged and discharged alternately by semiconductor devices with control electrode
22.
ABLATION PROBES WITH GUIDANCE INDICATORS TO SUPPORT LOCATION AND DIRECTION GUIDANCE SYSTEMS
An ablation probe includes an elongated needle portion comprising a distal end for positioning at a target tissue and a proximal end positioned away from the distal end and a guidance indicator positioned at the proximal end. The guidance indicator includes one or more markings or indicators to identify actual alignment of the probe relative to a preferred alignment.
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A radiotherapy system includes an X-ray target configured to convert an incident electron beam into a therapeutic X-ray beam, a purging magnet configured to redirect unwanted particles emitted from the X-ray target away from the therapeutic X-ray beam, and a particle collector configured to absorb the unwanted particles subsequent to redirection by the purging magnet. The particle collector may be configured to dissipate at least 50% of the energy of the incident electron beam.
H01J 35/10 - Rotary anodesArrangements for rotating anodesCooling rotary anodes
H01J 35/14 - Arrangements for concentrating, focusing, or directing the cathode ray
H01J 35/22 - X-ray tubes specially designed for passing a very high current for a very short time, e.g. for flash operation
H01J 35/30 - Tubes wherein the point of impact of the cathode ray on the anode or anticathode is movable relative to the surface thereof by deflection of the cathode ray
H05G 2/00 - Apparatus or processes specially adapted for producing X-rays, not involving X-ray tubes, e.g. involving generation of a plasma
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a first page of a first graphical user interface on the radiotherapy console associated with a radiotherapy machine in a treatment room, wherein the first graphical user interface contains a plurality of pages, each page corresponding to a stage of treatment implemented by the radiotherapy machine, and the first page corresponds to a first stage; and transitioning, by the server, the first page of the first graphical user interface to a second page of the first graphical user interface corresponding to a second stage responsive to an input of a user interacting with a second graphical interface presented on a display in the treatment room indicating that at least a predetermined portion of tasks associated with the first stage has been satisfied.
G06F 3/0483 - Interaction with page-structured environments, e.g. book metaphor
G06F 3/04847 - Interaction techniques to control parameter settings, e.g. interaction with sliders or dials
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
26.
METHODS OF USE OF ULTRA-HIGH DOSE RATE RADIATION AND THERAPEUTIC AGENT
Methods for treating tumors by administering FLASH radiation and a therapeutic agent to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining therapeutic agents with FLASH radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with a therapeutic agent based on patient-specific biomarker signatures. Also provided are radiation treatment planning methods and systems incorporating FLASH radiation and therapeutic agents.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
An ablation system includes a retractable sheath including a lumen; a first electrode in the lumen; a pre-bent telescopic tube extendable from the lumen and including a second electrode, wherein the first electrode and the second electrode are configured to deliver an electric field energy to target tissue in a patient.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
28.
PROBE SYSTEMS AND METHODS FOR IRREVERSIBLE ELECTROPORATION
An ablation system includes a retractable sheath including a lumen; a first electrode in the lumen; a pre-bent telescopic tube extendable from the lumen and including a second electrode, wherein the first electrode and the second electrode are configured to deliver an electric field energy to target tissue in a patient.
Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric ganglion, the aorticorenal ganglion and the aortic plexus. Planning of radiosurgical treatments will optionally employ a graphical representation of a blood/tissue interface adjacent these targets.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
30.
FLASH THERAPY TREATMENT PLANNING AND ONCOLOGY INFORMATION SYSTEM HAVING DOSE RATE PRESCRIPTION AND DOSE RATE MAPPING
Siemens Healthineers International AG (Switzerland)
Varian Medical Systems Particle Therapy GmbH (Germany)
Inventor
Smith, Christel
Koponen, Timo
Vanderstraeten, Reynald
Magliari, Anthony
Abel, Eric
Perez, Jessica
Folkerts, Michael
Khuntia, Deepak
Abstract
A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the number of beams, the directions of the beams, and the beam energy for each of the beams are determined such that the entire target receives the minimum prescribed dose. The operations further include prescribing a dose rate and optimizing dose rate constraints for FLASH therapy, and displaying a dose rate map of the FLASH therapy.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
A method includes determining skin characteristics in a region of a patient. An in-treatment optical scan is performed on a region of a patient, wherein the in-treatment optical scan comprises a near infrared (NIR) energy source. A plurality of detected signals is detected from the optical scan. The skin characteristics are filtered out from the plurality of detected signals. Skeletal anatomy positioning associated with the region is determined from the plurality of signals that is filtered.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A microsphere includes a radiopaque material, and a biodegradable material such that the microsphere can be detected using medical imaging and biodegrade after being administered to a patient.
A microsphere 70 includes a radiopaque material 22, and a biodegradable material 60 such that the microsphere can be detected using medical imaging and biodegrade after being administered to a patient.
A probe 200 for performing a cryoablation treatment that includes a handle 204 with a heater 220 configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A probe for performing a cryoablation treatment that includes a handle with a heater configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
36.
SYSTEMS AND METHODS FOR REAL-TIME TARGET VALIDATION FOR IMAGE-GUIDED RADIATION THERAPY
Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.
A method for a radiation therapy system comprises: causing a graphical representation of a movable support couch of the X-ray imaging system to be displayed, wherein the graphical representation includes one or more reference markers that each correspond to a respective physical feature of the movable support couch; receiving a first user input that includes a first position indicator that corresponds to a first boundary of an X-ray imaging region; and generating an X-ray image of the X-ray imaging region, wherein a first edge of the X-ray image corresponds to the first boundary.
A cryosurgical system includes a probe system including a cryosurgical probe and a temperature probe; an imaging system; and a computer system operatively connected to the probe system and the imaging system and programmed with a graphical depth guide application that provides a graphical overlay on an image from the imaging system that includes a first scale of first spaced markers representing temperature of the temperature probe and a second scale of second spaced markers representing a distance from the cryosurgical probe to an imaging probe of the imaging system that provide a visual guide for locating the cryosurgical probe during surgery.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
This disclosure relates to therapeutic combinations of TITR effectors such as CCR8 targeting agents, radiation therapy and checkpoint inhibitors and methods of using the same for the treatment of cancer. The disclosure also relates to methods of stratifying a patient population for treating with the therapeutic combination.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
SIEMENS HEALTHINEERS INTERNATIONAL AG (Switzerland)
Inventor
Honegger, Jonas Michael
Attanasi, Francesca
Abstract
Systems and methods for radioablation treatment planning are disclosed. In some examples, a computing device provides for display a user interface that allows a medical professional to define a target region of a patient for treatment. The user interface may allow the medical professional to select a treatment area using interactive target maps generated for the patient. The computing device also receives image data from an imaging system for the patient, such as image data identifying a 3D volume of the patient's scanned structure. The computing device may generate for display a 3D image of the scanned structure based on the received image data, and may superimpose on the 3D image a target region map that the medical professional can manipulate to define the target region of treatment for the patient. Once defined, the computing device may transmit the defined target region to a treatment system for treating the patient.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
41.
RADIATION TREATMENT PLANNING AND DELIVERY FOR MOVING TARGETS IN THE HEART
A radiation treatment planning system includes a computing device; and an interface for a user to communicate with the computing device and plan delivery of at least one radiation beam, wherein the computing device is configured to: acquire a calculated position of each of the at least one radiation beam required to treat a target tissue in a patient, wherein each of the positions is a function of a phase of a physiological cycle of the patient; determine dosages in the target tissue to be irradiated, wherein timing of some or all of the at least one radiation beam is based on the phase of the physiological cycle of the patient.
An ablation device includes a shaft and a radiofrequency (RF) emitter positioned in the shaft that delivers radiofrequency (RF) energy to create an ablation volume. The ablation device also includes an imaging sensor positioned in the tubular shaft configured to obtain imaging data of the ablation volume.
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
A probe and method of using a probe are disclosed. The probe may comprise a first member, a tip, a second member, and a third member. The first member may have a first and second end portions. The tip may be configured to engaged to the first member at the second end portion. The second member may be configured to extend and be positioned within the first member. The third member may be configured to be disposed outward of the second member along at least a portion of the second member, engage an inner surface of the first member, and define to least one passage between the third member and the first member. The probe may be coupled to a fluid supply and return, and fluid may flow within the probe, including within the passage defined between the first and third members.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
44.
SYSTEMS, METHODS, AND DEVICES FOR RADIATION BEAM ASYMMETRY MEASUREMENTS USING ELECTRONIC PORTAL IMAGING DEVICES
Systems and methods for determining beam asymmetry in a radiation treatment system using electronic portal imaging devices (EPIDs) without implementation of elaborate and complex EPID calibration procedures. The beam asymmetry is determined based on radiation scattered from different points in the radiation beam and measured with the same region of interest ROI of the EPID.
An ablation device includes a shaft and a radiofrequency (RF) emitter positioned in the shaft that delivers radiofrequency (RF) energy to create an ablation volume. The ablation device also includes an imaging sensor positioned in the tubular shaft configured to obtain imaging data of the ablation volume.
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
46.
SYSTEMS AND METHODS FOR PLANNING OF CARDIAC RADIATION THERAPY
Systems (104) and methods (400) for predicting a location of a target heart region for cardiac ablation can include one or more processors generating (402) a 3D model of a heart of a patient based on medical images of the patient, and estimating (404), using the 3D model of the heart and electrophysiology data of the patient, one or more mechanical properties that drive motion of the patient's heart. The one or more processors can generate (406), using the 3D model and the one or more mechanical properties, a simulated motion pattern of the patient's heart over at least a portion of a cardiac cycle, and identify (408) a region of interest (ROI) of the heart of the patient to be radiated. The one or more processors can determine (410), using the simulated motion pattern of the heart of the patient, a location of the ROI at a predefined time instance within the cardiac cycle.
Systems and methods (400) for simulating radiation effect for cardiac ablation can include a processor generating (402) a heart simulation model configured to simulate electrical activities of the heart of the patient. The processor can determine (404) a simulated post- radiation state of the heart of the patient by adjusting the heart simulation model to account for an effect of a radiation treatment plan on simulated electrical activities of the heart of the patient. The processor can simulate (406), using the adjusted heart simulation model, the simulated post-radiation state of the heart with a stimulation to induce a heart rhythm disorder, determine (408) whether the heart rhythm disorder is induced based on electrical activities generated when simulating the simulated post-radiation state of the heart with the stimulation, and output (410) an indication of whether the heart rhythm disorder is induced. The processor can suggest modifications to the radiation plan if the heart rhythm disorder is induced.
Systems and methods for cardiac radioablation treatment and planning are disclosed. In some examples, a computing device receives a first image of a patient that was captured for treatment planning. The computing device also receives target definition data characterizing a target area of the patient for treatment. Further, the computing device receives a second image of the patient captured on the day of, and prior to, treatment. The computing device determines whether there is a risk to an organ of the patient based on the first image, the target definition data, and the second image. The computing device also provides for display an indication of risk to the patient based on the determination. For example, the indication of risk can include a treatment target region and an organ at risk region superimposed over the second image. In some examples, the indication of risk includes expected dosage levels.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
49.
SYSTEMS AND METHODS FOR PLANNING OF CARDIAC RADIATION THERAPY
Systems and methods for predicting a location of a target heart region for cardiac ablation can include one or more processors generating a 3D model of a heart of a patient based on medical images of the patient, and estimating, using the 3D model of the heart and electrophysiology data of the patient, one or more mechanical properties that drive motion of the patient's heart. The one or more processors can generate, using the 3D model and the one or more mechanical properties, a simulated motion pattern of the patient's heart over at least a portion of a cardiac cycle, and identify a region of interest (ROI) of the heart of the patient to be radiated. The one or more processors can determine, using the simulated motion pattern of the heart of the patient, a location of the ROI at a predefined time instance within the cardiac cycle.
Systems and methods for simulating radiation effect for cardiac ablation can include a processor generating a heart simulation model configured to simulate electrical activities of the heart of the patient. The processor can determine a simulated post-radiation state of the heart of the patient by adjusting the heart simulation model to account for an effect of a radiation treatment plan on simulated electrical activities of the heart of the patient. The processor can simulate, using the adjusted heart simulation model, the simulated post-radiation state of the heart with a stimulation to induce a heart rhythm disorder, determine whether the heart rhythm disorder is induced based on electrical activities generated when simulating the simulated post-radiation state of the heart with the stimulation, and output an indication of whether the heart rhythm disorder is induced. The processor can suggest modifications to the radiation plan if the heart rhythm disorder is induced.
Siemens Healthineers International AG (Switzerland)
Inventor
Baltes, Christof
Holmes, Todd
Abstract
A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.
A method enables testing and evaluation of an expert human reviewer or an artificial intelligence (AI) error detection engine associated with a radiotherapy treatment planning process. Intentional errors are introduced into the output of a software module or AI engine that performs a certain step in the radiotherapy treatment planning process. The efficacy of the human or AI reviewer in detecting errors can then be evaluated or tested by determining whether the human or AI reviewer has detected the introduced error.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
53.
METHODS AND APPARATUS FOR AUTOMATICALLY DETERMINING RADIOABLATION TREATMENT RISK
Systems and methods for cardiac radioablation treatment and planning are disclosed. In some examples, a computing device receives a first image of a patient that was captured for treatment planning. The computing device also receives target definition data characterizing a target area of the patient for treatment. Further, the computing device receives a second image of the patient captured on the day of, and prior to, treatment. The computing device determines whether there is a risk to an organ of the patient based on the first image, the target definition data, and the second image. The computing device also provides for display an indication of risk to the patient based on the determination. For example, the indication of risk can include a treatment target region and an organ at risk region superimposed over the second image. In some examples, the indication of risk includes expected dosage levels.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
54.
FLUID-COOLED LOW-PROFILE MICROWAVE ABLATION PROBE WITH SPHERICAL ABLATION ZONE
A microwave ablation probe includes a cable extending in an axial direction and also includes an antenna configured to deliver Radio Frequency (RF) energy. The probe includes a shell positioned radially outward of the cable and a choke electrically coupled to an outer conductor of the cable. The probe also includes a cooling tube positioned inside the shell and positioned radially outward of the cable. The cooling tube including a first portion with a first outer diameter and a second portion with a second outer diameter. The second portion located radially outward of the choke and the second outer diameter being greater than the first outer diameter.
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
55.
APPARATUSES AND METHODS FOR COMBINATION RADIO FREQUENCY AND CRYO ABLATION TREATMENTS
A probe for performing an ablation treatment includes a shell defining an outer surface, a cooling path comprising an inflow path and a return path for a cryogen, and at least one radio frequency (RF) emitter. The probe is used to provide combination radio frequency (RF) and cryo treatments during a common procedure.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A probe for performing an ablation treatment includes a shell defining an outer surface and a cryogen supply conduit positioned within the shell. The probe also includes a flexible circuit positioned on at least a portion of the outer surface of the shell. The flexible circuit might include at least one radio frequency (RF) emitter for delivering RF energy to a target tissue.
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
57.
ABLATION PROBES INCLUDING FLEXIBLE CIRCUITS FOR HEATING AND SENSING
A probe for performing an ablation treatment includes a shell defining an outer surface and a cryogen supply conduit positioned in the shell. The probe also includes a flexible circuit positioned on at least a portion of the outer surface of the shell. The flexible circuit includes at least one radio frequency (RF) emitter for delivering RF energy to a target tissue.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
58.
DOSE-DIRECTED RADIATION THERAPY PLAN GENERATION USING COMPUTER MODELING TECHNIQUES
Provided herein are methods and systems to train and execute a computer model that uses artificial intelligence methodologies (e.g., deep learning) to learn and predict Multi-leaf Collimator (MLC) openings and control weights for a radiation therapy treatment plan.
A probe for performing an ablation treatment includes a shell defining an outer surface, a cooling path comprising an inflow path and a return path for a cryogen, and at least one radio frequency (RF) emitter. The probe is used to provide combination radio frequency (RF) and cryo treatments during a common procedure.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
60.
RADIOTHERAPY METHODS, SYSTEMS, AND WORKFLOW-ORIENTED GRAPHICAL USER INTERFACES
Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a radiotherapy machine comprising: a gantry having a screen in communication with a server, the screen configured to display a graphical user interface; and at least one camera, wherein the server is configured to present, in real time, images received from the at least one camera for display on a graphical user interface displayed on the screen.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
61.
GEOMETRIC ASPECTS OF RADIATION THERAPY PLANNING AND TREATMENT
Siemens Healthineers International AG (Switzerland)
Inventor
Vanderstraten, Reynald
Abel, Eric
Smith, Christel
Magliari, Anthony
Koponen, Timo
Star-Lack, Josh
Abstract
Radiation treatment planning includes determining a number of beams to be directed into a target, determining directions (e.g., gantry angles) for the beams, and determining an energy level for each of the beams. The number of beams, the directions of the beams, and the energy levels are determined such that the beams do not overlap outside the target and the prescribed dose will be delivered across the entire target.
A system can have an x-ray source that generates a series of individual x-ray pulses for multi-energy imaging. A first x-ray pulse can have a first energy level and a subsequent second x-ray pulse in the series can have a second energy level different from the first energy level. An x-ray imager can receive the x-rays from the x-ray source and can detect the received x-rays for image generation. A generator interface box (GIB) controls the x-ray source to provide the series of individual x-ray pulses and synchronizes detection by the x-ray imager with generation of the individual x-ray pulses. The GIB can control x-ray pulse generation and synchronization to optimize image generation while minimizing unnecessary x-ray irradiation.
H05G 1/58 - Switching arrangements for changing-over from one mode of operation to another, e.g. from radioscopy to radiography, from radioscopy to irradiation
H05G 1/60 - Circuit arrangements for obtaining a series of X-ray photographs or for X-ray cinematography
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
G01N 23/00 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or
G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
A method of performing a cryoablation treatment includes obtaining an ice formation model and preparing a cryoablation treatment plan based on the ice formation model and one or more characteristics of the target tissue. The method also includes initiating a cryoablation freezing cycle and obtaining ice formation data that describes one or more characteristics of ice being formed during the cryoablation freezing cycle. The method also includes determining a position of one or more isotherms of the ice being formed based on the ice formation data and the ice formation model.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
64.
APPARATUSES AND METHODS FOR ASYMMETRIC ICE FORMATION DURING CRYOABLATION TREATMENTS
A method of performing a cryoablation treatment includes initiating a flow of cryogen to a tip of the cryoprobe and obtaining ice formation data characterizing a shape of ice forming at a target tissue in a patient. The method also includes comparing the ice formation data to a predetermined ice formation profile and energizing a heating portion on the cryoprobe to limit growth of ice in a first direction relative to a predetermined location on the cryoprobe while the cryogen flows to the tip of the cryoprobe.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
65.
SYSTEM AND METHODS FOR QUANTIFICATION OF SUBSTANCE CONCENTRATION IN BODY STRUCTURES USING SPECTRAL COMPUTED TOMOGRAPHY
A method of determining a concentration of a chemical substance in a body of a patient includes adding 402 an additive quantity of an additive material to a base quantity of a chemical substance to obtain a mixed composition having a predetermined density and delivering 404 the mixed composition to the body of the patient. The method also includes obtaining 406 an image of at least a portion of the body of the patient and determining 408 a concentration of the chemical substance in the at least a portion of the body of the patient based on the image and the predetermined density of the mixed composition.
A device to measure radioactivity of a radioembolization material including a container 110 to receive the radioembolization material; and a dosimeter 140 that measures the radioactivity of the radioembolization material in the container while the radioembolization material is being administered to a patient.
A method (1200) of performing a cryoablation treatment includes initiating (1202) a flow of cryogen to a tip of the cryoprobe and obtaining (1204) ice formation data characterizing a shape of ice forming at a target tissue in a patient. The method (1200) also includes comparing (1206) the ice formation data to a predetermined ice formation profile and energizing (1210) a heating portion on the cryoprobe to limit growth of ice in a first direction relative to a predetermined location on the cryoprobe while the cryogen flows to the tip of the cryoprobe.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/08 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
68.
APPARATUSES AND METHODS FOR MODELLING AND CONTROL OF ICE FORMATION DURING CRYOABLATION TREATMENTS
A method (800) of performing a cryoablation treatment includes obtaining (808) an ice formation model and preparing (814) a cryoablation treatment plan based on the ice formation model and one or more characteristics of the target tissue. The method also includes initiating (816) a cryoablation freezing cycle and obtaining (818) ice formation data that describes one or more characteristics of ice being formed during the cryoablation freezing cycle. The method also includes determining a position of one or more isotherms of the ice being formed based on the ice formation data and the ice formation model.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
69.
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by the server for display on a screen associated with a radiotherapy machine, a series of consecutive graphical user interfaces, wherein each graphical user interface displays one or more graphical components corresponding to one or more tasks of one or more stages of a patient's radiotherapy treatment; and when a user operating the pendant interacts with a first controller of the pendant, the radiotherapy machine adjusts at least one of its configurations; and when the user interacts with a second controller of the pendant, the server revises the graphical user interface corresponding to the user's input.
A motion-enable device includes a mechanical switch and a capacitive sensor with a sensing region that is located adjacent to the mechanical switch. The mechanical switch enables a first signal when closed or actuated that indicates that the mechanical switch is in an active state. The capacitive sensor enables a second signal when a conductive object is disposed in the sensing region, where the second signal indicates that the capacitive sensor is in an active state. Enablement of operation of an apparatus depends on receipt of both the first signal and the second signal. The mechanical switch and the capacitive sensor act as the two separate switches required by functional safety requirements for a motion enable device. Because the sensing region of the capacitive sensor is adjacent to the mechanical switch, the first and second signals are generated when an operator actuates the mechanical switch with a single digit.
A61B 6/46 - Arrangements for interfacing with the operator or the patient
H01H 9/16 - Indicators for switching condition, e.g. "on" or "off"
H01H 13/02 - Switches having rectilinearly-movable operating part or parts adapted for pushing or pulling in one direction only, e.g. push-button switch Details
H01H 13/70 - Switches having rectilinearly-movable operating part or parts adapted for pushing or pulling in one direction only, e.g. push-button switch having a plurality of operating members associated with different sets of contacts, e.g. keyboard
H05G 1/58 - Switching arrangements for changing-over from one mode of operation to another, e.g. from radioscopy to radiography, from radioscopy to irradiation
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 17/00 - Surgical instruments, devices or methods
H03K 17/18 - Modifications for indicating state of switch
H03K 17/955 - Proximity switches using a capacitive detector
A method includes recording (S2) 3D data of an organ of interest after administering microbeads into a patient to flow to the organ; segmenting (S3) arterial vascular structures with visible accumulations of the microbeads around the organ; determining (S4) diameters or lumens(s) of the arterial vascular structures; determining or estimating (S5) a degree of a filling factor in the arterial vascular structures; generating (S6) a microbead density map along the arterial vascular structures; extrapolating (S7) the microbead accumulation in parenchyma and/or tumor tissue in the organ; and generating (S8) a composite distribution map of the microbeads, the composite map including the arterial vascular structures with visible accumulations of the microbeads and the extrapolated microbead accumulation in the parenchyma and/or tumor tissue in the organ.
A method of performing a radioembolization treatment includes injecting 402 a plurality of radioembolization particles into a bloodstream of a patient to treat a target tissue. Each radioembolization particle of the plurality of radioembolization particles includes a radioactive core and a radiopaque layer. The method also includes obtaining 404 an image of the target tissue and the radioembolization particles to determine 406 a dose of radioactivity delivered to the target tissue by the plurality of radioembolization particles, wherein the image is one of a computerized tomography (CT) image and an x-ray image.
A61K 51/12 - Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
A61L 24/02 - Surgical adhesives or cementsAdhesives for colostomy devices containing inorganic materials
A method of determining a concentration of a chemical substance in a body of a patient includes adding an additive quantity of an additive material to a base quantity of a chemical substance to obtain a mixed composition having a predetermined density and delivering the mixed composition to the body of the patient. The method also includes obtaining an image of at least a portion of the body of the patient and determining a concentration of the chemical substance in the at least a portion of the body of the patient based on the image and the predetermined density of the mixed composition.
A61K 51/12 - Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Downloadable computer software for machine quality assurance, namely, software for monitoring, measuring, collecting and analyzing machine quality assurance data; Downloadable computer software and hardware for performing machine quality assurance in compliance with industry standards; Downloadable computer software for providing guidance on compliance with machine quality assurance recommendations from professional societies and regulatory bodies; Downloadable computer software for performing quality assurance regarding image quality of images obtained in a treatment system; Downloadable computer software and hardware for performing quality assurance of film dosimetry; Downloadable computer database software for use in automating quality assurance assessment of a system; Downloadable computer software for accessing, viewing, and exporting data from electronic storage; Downloadable computer software for accessing, viewing, and exporting data and images; Downloadable computer software and hardware for use with an image guided radiation therapy device; Downloadable computer software for monitoring, measuring, collecting and analyzing machine quality assurance data in an automated fashion; Downloadable computer software for enabling integration of hardware devices for the purpose of analyzing radiation dosage output, machine geometry, and/or obtained image quality; Downloadable computer software to perform automatic evaluation of various components of a system and to display the evaluation results on a console; Downloadable computer software to perform quality assurance assessments regarding a treatment delivery system and display the evaluation results on a treatment console; Downloadable computer software for use in radiation treatment delivery systems, namely, for quality assurance of radiation treatment equipment including receiving, processing, verifying, and displaying data of linear accelerators; Downloadable computer software for operating information systems and processing electronic quality assurance information, namely, for collecting, organizing, compiling, analyzing and storing test results; Downloadable computer software for enabling and facilitating the uploading, downloading, displaying, creating and updating of electronic data and images for machine quality assurance; Downloadable computer software for defining machine quality assurance tests; Downloadable computer software for setting evaluation criteria and methods used in machine quality assurance analyses; Downloadable computer software for display of collected electronic machine quality data including trend graphing or other statistical analyses; Downloadable computer software for predictive maintenance analysis related to machine quality assurance; Downloadable computer software for alerts and/or notification of predicted maintenance due; Machine quality assurance phantoms being objects used as stand-ins for human tissues; Machine quality assurance systems, namely, including quality assurance phantoms being objects used as stand-ins for human tissues and downloadable software for performing machine quality assurance; Phantom holder being a holder for an object used as a stand-in for human tissues for use in machine quality assurance testing of medical imaging and medical treatment systems; Downloadable computer software for providing troubleshooting guidance based on results of machine quality assurance testing; Downloadable computer software for providing alerts and/or remote electronic notifications based on results of machine quality assurance testing and/or system self-checking; Downloadable computer software for managing a machine quality assurance program, including definition of quality assurance tasks, scheduling of quality assurance tasks, assignment of quality assurance tasks to personnel, and tracking status of quality assurance tasks; Downloadable computer software for collecting and aggregating status information of one or more systems and providing the status information electronically; all of the foregoing goods in the medical field. Medical imaging or treatment phantoms being objects used as stand-ins for human tissues to ensure that systems and methods for imaging or treating the human body are operating correctly and medical imaging or treatment phantom holders for use in machine quality assurance testing of medical imaging and medical treatment systems.
75.
RADIOTHERAPY METHODS, SYSTEMS, AND WORKFLOW-ORIENTED GRAPHICAL USER INTERFACES
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a graphical user interface for display on a screen positioned on a gantry of a radiotherapy machine, wherein the graphical user interface comprises a page corresponding to a radiotherapy treatment of a patient, wherein the page comprises a first graphical element indicating at least one attribute of the alignment data corresponding to the radiotherapy treatment of the patient.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Downloadable computer software for machine quality assurance, namely, software for monitoring, measuring, collecting and analyzing machine quality assurance data; Downloadable computer software and hardware for performing machine quality assurance in compliance with industry standards; Downloadable computer software for providing guidance on compliance with machine quality assurance recommendations from professional societies and regulatory bodies; Downloadable computer software for performing quality assurance regarding image quality of images obtained in a treatment system; Downloadable computer software and hardware for performing quality assurance of film dosimetry; Downloadable computer database software for use in automating quality assurance assessment of a system; Downloadable computer software for accessing, viewing, and exporting data from electronic storage; Downloadable computer software for accessing, viewing, and exporting data and images; Downloadable computer software and hardware for use with an image guided radiation therapy device; Downloadable computer software for monitoring, measuring, collecting and analyzing machine quality assurance data in an automated fashion; Downloadable computer software for enabling integration of hardware devices for the purpose of analyzing radiation dosage output, machine geometry, and/or obtained image quality; Downloadable computer software to perform automatic evaluation of various components of a system and to display the evaluation results on a console; Downloadable computer software to perform quality assurance assessments regarding a treatment delivery system and display the evaluation results on a treatment console; Downloadable computer software for use in radiation treatment delivery systems, namely, for quality assurance of radiation treatment equipment including receiving, processing, verifying, and displaying data of linear accelerators; Downloadable computer software for operating information systems and processing electronic quality assurance information, namely, for collecting, organizing, compiling, analyzing and storing test results; Downloadable computer software for enabling and facilitating the uploading, downloading, displaying, creating and updating of electronic data and images for machine quality assurance; Downloadable computer software for defining machine quality assurance tests; Downloadable computer software for setting evaluation criteria and methods used in machine quality assurance analyses; Downloadable computer software for display of collected electronic machine quality data including trend graphing or other statistical analyses; Downloadable computer software for predictive maintenance analysis related to machine quality assurance; Downloadable computer software for alerts and/or notification of predicted maintenance due; Machine quality assurance phantoms being objects used as stand-ins for human tissues; Machine quality assurance systems, namely, including quality assurance phantoms being objects used as stand-ins for human tissues and downloadable software for performing machine quality assurance; Phantom holder being a holder for an object used as a stand-in for human tissues for use in machine quality assurance testing of medical imaging and medical treatment systems; Downloadable computer software for providing troubleshooting guidance based on results of machine quality assurance testing; Downloadable computer software for providing alerts and/or remote electronic notifications based on results of machine quality assurance testing and/or system self-checking; Downloadable computer software for managing a machine quality assurance program, including definition of quality assurance tasks, scheduling of quality assurance tasks, assignment of quality assurance tasks to personnel, and tracking status of quality assurance tasks; Downloadable computer software for collecting and aggregating status information of one or more systems and providing the status information electronically; all of the foregoing goods in the medical field
(2) Phantoms being objects used as stand-ins for human tissues and phantom holders for use in machine quality assurance testing of medical imaging and medical treatment systems
An apparatus in a radiation therapy system includes: a base configured to support a first quality assurance phantom at a first position and a second quality assurance phantom at a second position; and at least one coupling element. The at least one coupling element is configured to: mate with at least one indexing feature of a first patient treatment couch of the radiation therapy system; and fix a position of the base relative to the first patient treatment couch.
An apparatus in a radiation therapy system includes: a base 401 configured to support a first quality assurance phantom 451 at a first position and a second quality assurance phantom 452 at a second position; and at least one coupling element 431. The at least one coupling element is configured to: mate with at least one indexing feature 531 of a first patient treatment couch 480 of the radiation therapy system; and fix a position of the base relative to the first patient treatment couch.
Presented systems and methods enable efficient and effective radiation planning and treatment, including accurate and convenient transmission of the radiation towards a tissue target. In one embodiment, a radiation system includes an electron gun, a bend magnet, a scan control component, and an electron beam entry angle control component. The electron gun is configured to generate electrons. The linear accelerator is configured to accelerate the electrons in an electron beam. The bend magnet is configured to bend the path of the electron beam. The scan control component controls movement of the electron beam in a scan pattern. The electron beam entry angle control component is configured to control the entry angle of the electron beam.
An electron applicator, which is used along with a linear accelerator in a FLASH radiotherapy treatment program, includes an integrated dosimeter for accurately measuring the FLASH radiation levels, and an interchangeable high-density polymer cutout which can be easily, inexpensively, and accurately formed to match the irregular shape of a tumor.
Misconnected applicators are eliminated in a brachytherapy treatment system by associating the output channels of an afterloader with the channel numbers after the applicators have been coupled to the output channels. In addition, the brachytherapy treatment system ensures the delivery of a proper dose by identifying the exact locations of the distal ends of the applicators right before the radiation treatment is to begin, and determining the final dose based on the exact locations.
Presented systems and methods enable efficient and effective radiation planning and treatment, including accurate and convenient transmission of the radiation towards a tissue target. In one embodiment, a radiation system 200A includes an electron gun 211, a bend magnet 215, a scan control component 220, and an electron beam entry angle control component 230. The electron gun is configured to generate electrons. A linear accelerator 212 is configured to accelerate the electrons in an electron beam. The bend magnet is configured to bend the path of the electron beam. The scan control component controls movement of the electron beam in a scan pattern. The electron beam entry angle control component is configured to control the entry angle of the electron beam.
Misconnected applicators are eliminated in a brachytherapy treatment system (200) by associating the output channels of an afterloader (216) with the channel numbers after the applicators (210) have been coupled to the output channels. In addition, the brachytherapy treatment system (200) ensures the delivery of a proper dose by identifying the exact locations of the distal ends (210D) of the applicators (210) right before the radiation treatment is to begin, and determining the final dose based on the exact locations.
A system to perform cryoablation treatments includes at least one computing device configured to obtain at least one impedance measurement from a cryoprobe and determine whether a bleeding condition is present at a treatment site proximate the cryoprobe based on the at least one impedance measurement. The at least one computing device also adjusts one or more inputs to a heater in the cryoprobe when the at least one impedance measurements indicate that the bleeding condition is present.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
85.
APPARATUSES AND METHODS FOR SEQUENTIAL HEATING OF CRYO-FLUID IN CRYOABLATION SYSTEMS
A system for performing a cryoablation treatment may include at least one computing device (102) configured to obtain temperature information at a plurality of heating locations (110, 112, 114, 116) on a cryo-fluid supply (124). The plurality of heating locations includes a first heating location and a second heating location. The computing device is also configured to compare a first temperature at the first heating location to an expected first temperature and to initiate a first heating cycle at the first heating location if the first temperature at the first heating location is less than the expected first temperature. The computing device also compares a second temperature at the second heating location to an expected second temperature wherein the second heating location disposed downstream of the first heating location and initiates a second heating cycle at the second heating location if the second temperature is less than the expected second temperature.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
86.
APPARATUSES AND METHODS FOR SEQUENTIAL HEATING OF CRYO-FLUID IN CRYOABLATION SYSTEMS
A system for performing a cryoablation treatment may include at least one computing device configured to obtain temperature information at a plurality of heating locations on a cryo-fluid supply. The plurality of heating locations includes a first heating location and a second heating location. The computing device is also configured to compare a first temperature at the first heating location to an expected first temperature and to initiate a first heating cycle at the first heating location if the first temperature at the first heating location is less than the expected first temperature. The computing device also compares a second temperature at the second heating location to an expected second temperature wherein the second heating location disposed downstream of the first heating location and initiates a second heating cycle at the second heating location if the second temperature is less than the expected second temperature.
G05D 23/19 - Control of temperature characterised by the use of electric means
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
87.
APPARATUSES AND METHODS FOR THE CONTROL AND OPTIMIZATION OF ICE FORMATION DURING CRYOABLATION TREATMENTS
A method of performing a cryoablation treatment may include positioning a plurality of measurement points in predetermined locations relative to a target tissue in a patient and obtaining ice formation measurement information from the plurality of measurement points. The method may also include comparing the ice formation measurement information to a predetermined ice formation plan and adjusting a flow of a cryo-fluid to a cryoprobe if the ice formation measurement information deviates from the predetermined ice formation plan by more than predetermined deviation level.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
88.
APPARATUSES AND METHODS FOR ADAPTIVELY CONTROLLING CRYOABLATION SYSTEMS
A system for performing cryoablation treatments includes at least one computing device that is configured to obtain cryoablation operating information from one or more sensors coupled to a cryoablation treatment apparatus and to obtain patient information from one or more patient monitoring apparatuses. The computing device also obtains ice formation information characterizing one or more characteristics of an iceball produced by the cryoablation treatment apparatus and compares the ice formation information to an ice formation plan. If the ice formation information differs from the ice formation plan, the computing device adjusts one or more operating parameters of the cryoablation treatment apparatus.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
A radiotherapy system (100) includes an X-ray target (50, 350) configured to convert an incident electron beam (45) into a therapeutic X-ray beam (210), a purging magnet (230) configured to redirect unwanted particles (235) emitted from the X-ray target (50, 350) away from the therapeutic X-ray beam (210), and a particle collector (240) configured to absorb the unwanted particles (235) subsequent to redirection by the purging magnet (230). The particle collector (240) may be configured to dissipate at least 50% of the energy of the incident electron beam (45).
A system for performing cryoablation treatments includes at least one computing device that is configured to obtain (402) cryoablation operating information from one or more sensors coupled to a cryoablation treatment apparatus and to obtain (404) patient information from one or more patient monitoring apparatuses. The computing device also obtains (406) ice formation information characterizing one or more characteristics of an iceball produced by the cryoablation treatment apparatus and compares (408) the ice formation information to an ice formation plan. If the ice formation information differs from the ice formation plan, the computing device adjusts (410) one or more operating parameters of the cryoablation treatment apparatus.
A method of performing a cryoablation treatment may include positioning 804 a plurality of measurement points in predetermined locations relative to a target tissue in a patient and obtaining 808 ice formation measurement information from the plurality of measurement points. The method may also include comparing 810 the ice formation measurement information to a predetermined ice formation plan and adjusting 812 a flow of a cryo-fluid to a cryoprobe if the ice formation measurement information deviates from the predetermined ice formation plan by more than predetermined deviation level.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
92.
APPARATUSES AND METHODS FOR MONITORING AND CONTROLLING BLEEDING DURING CRYOABLATION TREATMENTS
A system to perform cryoablation treatments includes at least one computing device (202) configured to obtain at least one impedance measurement from a cryoprobe (212) and determine whether a bleeding condition is present at a treatment site proximate the cryoprobe based on the at least one impedance measurement. The at least one computing device also adjusts one or more inputs to a heater (214) in the cryoprobe when the at least one impedance measurements indicate that the bleeding condition is present.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
93.
DRIVING DETERMINISTIC DOSE DEPOSITIONS WITH MONTE CARLO SOURCE MODELING
Embodiments described herein provide for coupling Monte Carlo source modeling with deterministic dose calculations. An internal volumetric first scatter distributed source of a patient is determined using Monte Carlo simulations and ingested into one or more dosing algorithms. The dosing algorithms use the source model to determine a dose deposition.
Embodiments described herein provide for training an artificial intelligence model (200, 300) to boost dose depositions. The artificial intelligence model (200, 300) receives medical images and a dose deposition determined according to a first dose deposition model. The artificial intelligence model (200, 300) modifies the received dose deposition determined according to the first dose deposition model such that the dose deposition simulates a dose deposition determined by a second dose deposition model.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises retrieving, by a server, information from a radiotherapy file associated with a patient, the information comprising an alignment data of at least a treatment region of the patient; presenting, by the server, for display on a graphical user interface, an image corresponding to the patient positioned on a couch of a radiotherapy machine, the image comprising an overlay on a surface of the patient in the treatment region; and presenting, by the server, for display, a visually distinct revised overlay for at least a portion of the surface of the patient in the treatment region that matches, within a predetermined margin of error, the alignment data.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61B 6/04 - Positioning of patientsTiltable beds or the like
G06T 15/00 - 3D [Three Dimensional] image rendering
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
A61B 6/46 - Arrangements for interfacing with the operator or the patient
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
A radiation suite includes a room having a floor, a ceiling, and one or more walls, a radiation system including a gantry enclosing a radiation source and a couch, and an image projection system operable to project an image on a projection surface on at least a portion of the gantry and/or the couch, providing a calming environment for a patient to relax. The image projection system comprises a computer and one or more projectors operably controlled by the computer. The computer comprises a mapping software operable to map an image file to the projection surface. The one or more projectors are operable to project the mapped image file on the projection surface.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61M 21/00 - Other devices or methods to cause a change in the state of consciousnessDevices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
G01N 21/3563 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solidsPreparation of samples therefor
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
(1) Medical devices, namely, microcatheters and other catheters; Medical devices, namely, syringes and delivery catheters for the delivery of embolic agents; Medical devices for use in treating or diagnosing conditions within the peripheral vasculature with the use of microcatheters and other catheters; Medical apparatus and instruments for use in medical diagnostic, imaging, and delivery of therapeutic materials; Intravascular medical imaging apparatus; Intravascular medical imaging accessories, namely, microcatheters and other introduction catheters and guidewires; Medical apparatus, namely, system for vascular embolization procedures in the nature of catheters; Medical device for embolization therapy in interventional radiology and oncology; Medical device for vascular embolization procedures
Medical devices, namely, microcatheters and other catheters; all relating to vascular interventions; Medical devices, namely, syringes and delivery catheters for the delivery of embolic agents; Medical devices for use in treating or diagnosing conditions within the peripheral vasculature with the use of microcatheters and other catheters; Medical apparatus and instruments for use in medical diagnostic, imaging, and delivery of therapeutic materials; all relating to vascular interventions; Intravascular medical imaging apparatus; Intravascular medical imaging accessories, namely, microcatheters and other introduction catheters and guidewires; Medical apparatus, namely, system for vascular embolization procedures in the nature of catheters; Medical device for embolization therapy in interventional radiology and oncology; Medical device for vascular embolization procedures.
99.
DOSE ASPECTS OF RADIATION THERAPY PLANNING AND TREATMENT
Siemens Healthineers International AG (Switzerland)
Inventor
Vanderstraeten, Reynald Vanderstraeten
Abel, Eric
Smith, Christel
Magliari, Anthony
Koponen, Timo
Mansfield, Stanley
Adelsheim, Charles
Abstract
Radiation treatment planning includes accessing values of parameters such as a number of beams to be directed into sub-volumes in a target, beam directions, and beam energies. Information that specifies limits for the radiation treatment plan are accessed. The limits include a limit on irradiation time for each sub-volume outside the target. Other limits can include a limit on irradiation time for each sub-volume in the target, a limit on dose rate for each sub volume in the target, and a limit on dose rate for each sub-volume outside the target. The values of the parameters are adjusted until the irradiation time for each sub-volume outside the target satisfies the maximum limit on irradiation time.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
100.
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
A method comprises presenting, by a server for display on a screen associated with a radiotherapy machine, a series of consecutive graphical user interfaces (GUIs), wherein a first GUI comprises: a first graphical indicator (GI) corresponding to a first attribute associated with configuration of the radiotherapy machine, and a second GI corresponding to a second attribute associated with the patient; when the server receives an indication that a user interacting with a pendant in communication with the server has inputted a first input corresponding to a first direction towards the first GI, presenting for display a second GUI comprising data associated with the first attribute; and when the server receives an indication that the user has inputted a second input corresponding to a second direction towards the second GI, presenting for display a third GUI comprising data associated with the second attribute.
