Zhejiang Kanglaite Group Co., Ltd.

China

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IPC Class
A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates 12
A61K 36/8994 - Coix (Job's tears) 12
A61K 9/14 - Particulate form, e.g. powders 12
A61K 9/20 - Pills, lozenges or tablets 12
A61P 35/00 - Antineoplastic agents 12
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1.

Coix seed oil containing 11 triglycerides, and pharmaceutical preparation and use thereof

      
Application Number 15324873
Grant Number 10314878
Status In Force
Filing Date 2015-07-17
First Publication Date 2017-07-27
Grant Date 2019-06-11
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

Coix seed oil contains 11 triglyceride ingredients in the following mass percentages: trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76% and 1-palmitin-2,3-diolein 8.06-11.58%, 1-olein-2-linolein-3-stearin 1.37-1.97%, 1,3-dipalmitin-2-olein 1.52-2.19% and 1,2-diolein-3-stearin 1.29-1.86%.

IPC Classes  ?

  • A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/08 - Solutions
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
  • A61K 31/231 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • C07C 69/30 - Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with trihydroxylic compounds
  • C07C 69/58 - Esters of straight chain acids with eighteen carbon atoms in the acid moiety
  • C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
  • C11B 1/10 - Production of fats or fatty oils from raw materials by extracting
  • C11B 3/00 - Refining fats or fatty oils
  • A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
  • A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

2.

Coix seed oil containing 16 glycerides, and pharmaceutical preparation and use thereof

      
Application Number 15324890
Grant Number 10596218
Status In Force
Filing Date 2015-07-17
First Publication Date 2017-07-27
Grant Date 2020-03-24
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

Coix seed oil contains 5 diglyceride and 11 triglyceride ingredients in the following mass percentages: 1,3-diolein 0.40-0.58%, 1-linolein-3-olein 0.91-1.31%, 1,2-diolein 0.24-0.35%, 1-olein-2-linolein 0.66-0.95%, 1,2-dilinolein 0.33-0.47%, trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76%, 1-palmitin-2,3-diolein 8.06-11.58%, 1-olein-2-linolein-3-stearin 1.37-1.97%, 1,3-dipalmitin-2-olein 1.52-2.19% and 1,2-diolein-3-stearin 1.29-1.86%.

IPC Classes  ?

  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/08 - Solutions
  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/231 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
  • A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

3.

PHARMACEUTICAL COMPOUND COMPRISING 13 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Document Number 02954792
Status In Force
Filing Date 2015-07-17
Open to Public Date 2016-01-21
Grant Date 2019-10-29
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A pharmaceutical compound comprising glycerides, formulation, and preparation method and application thereof. The pharmaceutical compound specifically consists of the following 13 compounds: 1,3-dioleate diglyceride (0.41-0.59%), 1-linoleate-3-oleate diglyceride (0.93-1.33%), 1,2-dilinoleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.68-0.97%), 1,2-dilinoleate glyceride (0.33-0.48%), glyceryl trilinoleate (2.01-2.89%), glyceryl 1-oleate-2,3-dilinoleate (23.46-33.72%), glyceryl 1-palmitate-2,3-dilinoleate (3.33-4.78%), glyceryl 1,3-dioleate-2-linoleate (21.6-31.05%), glyceryl 1-palmitate-2-linoleate-3-oleate (9.99-14.35%), glyceryl 1,3-dipalmitate-2-linoleate (0.39-17.80%), glyceryl trioleate (12.39-17.80%), and glyceryl 1-palmitate-2,3-dioleate (4.26-6.12%).

IPC Classes  ?

  • A61K 9/107 - Emulsions
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
  • A61P 35/00 - Antineoplastic agents
  • A61P 37/00 - Drugs for immunological or allergic disorders

4.

COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Document Number 02954796
Status In Force
Filing Date 2015-07-17
Open to Public Date 2016-01-21
Grant Date 2019-10-29
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 13 triglycerides extracted from coix seeds, formulation and application thereof. Specifically, the coix seed oil comprises the following 11 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.

IPC Classes  ?

  • A61K 9/08 - Solutions
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61P 35/00 - Antineoplastic agents

5.

COIX SEED OIL COMPRISING 16 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Document Number 02954797
Status In Force
Filing Date 2015-07-17
Open to Public Date 2016-01-21
Grant Date 2019-10-29
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 16 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 11 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-0.58%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.

IPC Classes  ?

  • A61K 9/08 - Solutions
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61P 35/00 - Antineoplastic agents

6.

GLYCERYL 1, 3-DIOLEATE-2-LINOLEATE COMPOUND, FORMULATION, AND PREPARATION METHOD AND APPLICATION THEREOF

      
Application Number CN2015084289
Publication Number 2016/008436
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

The present invention relates to a compound having the structure (I): glyceryl 1,3-dioleate-2-linoleate; the present invention also comprises the method of obtaining the compound of the present invention by the preparation of coix seed oil from a raw material of coix seed powder, the preliminary isolation of glyceryl 1,3-dioleate-2-linoleate, and the secondary isolation of same. The present invention also relates to a pharmaceutical formulation containing glyceryl 1,3-dioleate-2-linoleate, the preparation method thereof, and the application of said compound and said formulation as an anti-tumour medicine.

IPC Classes  ?

  • C07C 67/48 - SeparationPurificationStabilisationUse of additives
  • C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
  • A61K 31/225 - Polycarboxylic acids
  • A61P 35/00 - Antineoplastic agents

7.

COIX SEED OIL COMPRISING 8 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Application Number CN2015084293
Publication Number 2016/008439
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 8 triglycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 8 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), and glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%). The coix seed oil can be used in anti-tumour medicine, or in medicine to treat inflammation.

IPC Classes  ?

  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/08 - Solutions
  • A61P 13/08 - Drugs for disorders of the urinary system of the prostate
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
  • A61P 35/00 - Antineoplastic agents

8.

COIX SEED OIL COMPRISING 13 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Application Number CN2015084294
Publication Number 2016/008440
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 13 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 8 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-0.58%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), and glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%). The coix seed oil can be used in anti-tumour medicine, or in medicine to treat inflammation.

IPC Classes  ?

  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/08 - Solutions
  • A61P 13/08 - Drugs for disorders of the urinary system of the prostate
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
  • A61P 35/00 - Antineoplastic agents

9.

PHARMACEUTICAL COMPOUND COMPRISING 13 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Application Number CN2015084295
Publication Number 2016/008441
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A pharmaceutical compound comprising glycerides, formulation, and preparation method and application thereof. The pharmaceutical compound specifically consists of the following 13 compounds: 1,3-dioleate diglyceride (0.41-0.59%), 1-linoleate-3-oleate diglyceride (0.93-1.33%), 1,2-dilinoleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.68-0.97%), 1,2-dilinoleate glyceride (0.33-0.48%), glyceryl trilinoleate (2.01-2.89%), glyceryl 1-oleate-2,3-dilinoleate (23.46-33.72%), glyceryl 1-palmitate-2,3-dilinoleate (3.33-4.78%), glyceryl 1,3-dioleate-2-linoleate (21.6-31.05%), glyceryl 1-palmitate-2-linoleate-3-oleate (9.99-14.35%), glyceryl 1,3-dipalmitate-2-linoleate (0.39-17.80%), glyceryl trioleate (12.39-17.80%), and glyceryl 1-palmitate-2,3-dioleate (4.26-6.12%).

IPC Classes  ?

  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/107 - Emulsions
  • A61P 35/00 - Antineoplastic agents
  • A61P 37/00 - Drugs for immunological or allergic disorders
  • A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

10.

COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Application Number CN2015084297
Publication Number 2016/008442
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 13 triglycerides extracted from coix seeds, formulation and application thereof. Specifically, the coix seed oil comprises the following 11 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.

IPC Classes  ?

  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/08 - Solutions
  • A61P 35/00 - Antineoplastic agents

11.

COIX SEED OIL COMPRISING 16 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Application Number CN2015084298
Publication Number 2016/008443
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 16 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 11 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-0.58%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.

IPC Classes  ?

  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/08 - Solutions
  • A61P 35/00 - Antineoplastic agents

12.

COIX SEED OIL COMPRISING 13 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Document Number 02954688
Status In Force
Filing Date 2015-07-17
Open to Public Date 2016-01-21
Grant Date 2019-10-29
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A coix seed oil comprising 13 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 8 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-058%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), and glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%). The coix seed oil can be used in anti-tumour medicine, or in medicine to treat inflammation.

IPC Classes  ?

  • A61K 9/08 - Solutions
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61P 13/08 - Drugs for disorders of the urinary system of the prostate
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
  • A61P 35/00 - Antineoplastic agents

13.

GLYCERYL 1-PALMITATE-2-LINOLEATE-3-OLEATE COMPOUND, FORMULATION, AND PREPARATION METHOD AND APPLICATION THEREOF

      
Application Number CN2015084290
Publication Number 2016/008437
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

The present invention relates to a compound having the structure (I): glyceryl 1-palmitate-2-linoleate-3-oleate; the present invention also comprises the method of obtaining the compound of the present invention by the preparation of coix seed oil from a raw material of coix seed powder, the preliminary isolation of glyceryl 1-palmitate-2-linoleate-3-oleate, and the secondary isolation of same. The present invention also relates to a pharmaceutical formulation containing said compound having structure (I), the preparation method thereof, and the application of said compound and said formulation as an anti-tumour medicine.

IPC Classes  ?

  • C07C 67/48 - SeparationPurificationStabilisationUse of additives
  • C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
  • A61K 31/225 - Polycarboxylic acids
  • A61P 35/00 - Antineoplastic agents

14.

PHARMACEUTICAL COMPOSITION COMPRISING 8 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

      
Application Number CN2015084292
Publication Number 2016/008438
Status In Force
Filing Date 2015-07-17
Publication Date 2016-01-21
Owner ZHEJIANG KANGLAITE GROUP CO., LTD. (China)
Inventor Li, Dapeng

Abstract

A pharmaceutical compound, formulation and application thereof. The compound consists of the following components: glyceryl trilinoleate, glyceryl 1-oleate-2,3-dilinoleate, glyceryl 1-palmitate-2,3-dilinoleate, glyceryl1,3-dioleate-2-linoleate, glyceryl 1-palmitate-2-linoleate-3-oleate, glyceryl 1,3-dipalmitate-2-linoleate, glyceryl trioleate, and glyceryl 1-palmitate-2,3-dioleate. The composition can be used in anti-tumour medicine, or in medicine to improve immune response.

IPC Classes  ?

  • A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
  • A61K 36/8994 - Coix (Job's tears)
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • A61K 9/10 - DispersionsEmulsions
  • A61K 9/08 - Solutions
  • A61P 35/00 - Antineoplastic agents
  • A61P 37/04 - Immunostimulants

15.

KANGLAITE

      
Serial Number 75342725
Status Registered
Filing Date 1997-08-18
Registration Date 1999-12-21
Owner ZHEJIANG KANGLAITE GROUP COMPANY LIMITED (China)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

pharmaceutical preparations for use in the treatment of arthritis, lupus, and cancer, sold in the form of injections, capsules, ointments, and pills; medicated compresses; dietetic beverages adapted for medical purposes; wound dressing and surgical dressings; medicinal drinks in the nature of herbal teas and syrups; and sterilization preparations for use in cleaning wounds