A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
A61K 31/21 - Esters, e.g. nitroglycerine, selenocyanates
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 31/231 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
C07C 69/30 - Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with trihydroxylic compounds
C07C 69/58 - Esters of straight chain acids with eighteen carbon atoms in the acid moiety
C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
C11B 1/10 - Production of fats or fatty oils from raw materials by extracting
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
2.
Coix seed oil containing 16 glycerides, and pharmaceutical preparation and use thereof
A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/231 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
3.
PHARMACEUTICAL COMPOUND COMPRISING 13 GLYCERIDES, FORMULATION AND APPLICATION THEREOF
A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A coix seed oil comprising 13 triglycerides extracted from coix seeds, formulation and application thereof. Specifically, the coix seed oil comprises the following 11 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.
The present invention relates to a compound having the structure (I): glyceryl 1,3-dioleate-2-linoleate; the present invention also comprises the method of obtaining the compound of the present invention by the preparation of coix seed oil from a raw material of coix seed powder, the preliminary isolation of glyceryl 1,3-dioleate-2-linoleate, and the secondary isolation of same. The present invention also relates to a pharmaceutical formulation containing glyceryl 1,3-dioleate-2-linoleate, the preparation method thereof, and the application of said compound and said formulation as an anti-tumour medicine.
A coix seed oil comprising 8 triglycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 8 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), and glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%). The coix seed oil can be used in anti-tumour medicine, or in medicine to treat inflammation.
A coix seed oil comprising 13 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 8 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-0.58%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), and glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%). The coix seed oil can be used in anti-tumour medicine, or in medicine to treat inflammation.
A61P 37/00 - Drugs for immunological or allergic disorders
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
10.
COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF
A coix seed oil comprising 13 triglycerides extracted from coix seeds, formulation and application thereof. Specifically, the coix seed oil comprises the following 11 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.
A coix seed oil comprising 13 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 8 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-058%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), and glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%). The coix seed oil can be used in anti-tumour medicine, or in medicine to treat inflammation.
The present invention relates to a compound having the structure (I): glyceryl 1-palmitate-2-linoleate-3-oleate; the present invention also comprises the method of obtaining the compound of the present invention by the preparation of coix seed oil from a raw material of coix seed powder, the preliminary isolation of glyceryl 1-palmitate-2-linoleate-3-oleate, and the secondary isolation of same. The present invention also relates to a pharmaceutical formulation containing said compound having structure (I), the preparation method thereof, and the application of said compound and said formulation as an anti-tumour medicine.
A pharmaceutical compound, formulation and application thereof. The compound consists of the following components: glyceryl trilinoleate, glyceryl 1-oleate-2,3-dilinoleate, glyceryl 1-palmitate-2,3-dilinoleate, glyceryl1,3-dioleate-2-linoleate, glyceryl 1-palmitate-2-linoleate-3-oleate, glyceryl 1,3-dipalmitate-2-linoleate, glyceryl trioleate, and glyceryl 1-palmitate-2,3-dioleate. The composition can be used in anti-tumour medicine, or in medicine to improve immune response.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations for use in the treatment of arthritis, lupus, and cancer, sold in the form of injections, capsules, ointments, and pills; medicated compresses; dietetic beverages adapted for medical purposes; wound dressing and surgical dressings; medicinal drinks in the nature of herbal teas and syrups; and sterilization preparations for use in cleaning wounds