A frequency-shift symmetric chirp spread spectrum modulation and demodulation method for interstellar communication links. The transmission process includes several steps: serial-to-parallel conversion, index addition, Gray coding, binary-to-decimal conversion, and frequency-shift symmetric chirp spread spectrum modulation. On the other hand, the reception process comprises demodulation of the symmetric chirp signal, fast Fourier transform, peak retrieval, decimal-to-binary conversion, Gray decoding, index removal, and parallel-to-serial conversion. The frame structure includes a preamble code, synchronization word, and user data. The symmetric chirp signal includes a pair of chirp signals with opposite polarities, ensuring the continuity of phase and frequency during the signal concatenation process. Compared to traditional chirp signals, the symmetric chirp signal exhibits superior correlation characteristics, enhanced noise resistance, and improved Doppler tolerance, making it particularly suitable for interstellar communication links.
A distributed multi-antenna collaborative phase stabilization device for future broadband wireless communication. The device includes a central station and various antenna terminals interconnected via optical fibers to form a linear communication system. The distributed multi-antenna reception signals are optically modulated at the antenna terminals into different wavelengths of optical signals, and then coupled into a single optical fiber using wavelength division multiplexing technology for transmission to the central station. At the central station, the optical signals are converted back into the original RF (radio frequency) signals through optoelectronic conversion.
The present disclosure provides an in-situ testing system of metal materials under high temperature and complex loads. The testing system includes a fatigue testing unit, a high-temperature loading unit, a signal detecting unit and a base. The fatigue testing unit is configured for pre-tightening a sample and then performing a fatigue testing on the sample. The high-temperature loading unit is configured for heating the sample to a high temperature. The signal detecting unit includes a pressure sensor and a displacement sensor. The pressure sensor is configured for monitoring the tensile force on the sample. The displacement sensor is configured for monitoring the displacement of the sample after being stretched during the pre-tightening of the sample. The base is configured for bearing the fatigue testing unit, the high-temperature loading unit and the signal detecting unit, and can be positioned on a scanning electron microscope stage or an open microscopic device.
The present disclosure provides a method and device for performing signal communication based on a levitated particle. In one example, the method includes: preparing a levitated state of the particle; regulating and measuring a net charge quantity carried by the levitated particle; calibrating electromagnetic response characteristics of the levitated particle; applying an electromagnetic communication signal; obtaining and demodulating the electromagnetic communication signal. In an example, the device includes: a levitation trapper; a charge measure-regulator; an electromagnetic response calibrator, configured to obtain, in advance, a background noise and an electromagnetic response transfer function of the levitated particle; a communication signal detect-demodulator, configured to detect a motion response of the levitated particle under an electromagnetic communication signal; based on the background noise and the electromagnetic response transfer function of the levitated particle, recover the applied electromagnetic communication signal from the detected motion response, and demodulate symbols of the electromagnetic communication signal.
A method for simultaneously separating and purifying myricetin-3-O-(2″-O-galloyl)-a-L-rhamnoside and myricetin-3-O-(4″-O-galloyl)-a-L-rhamnoside from Bayberry leaves, and the use of the compounds prepared by the method. The method includes: (1) alcohol extraction and concentration: mixing Bayberry leaves with an alcohol solution; (2) solid-phase extraction column adsorption: injecting the crude Bayberry leaf flavonol alcohol extract into a solid-phase extraction column; washing with a mobile phase for the first gradient elution; (3) preparative liquid chromatography purification: using a solid-phase chromatography column; wherein the solid-phase extraction powder obtained from step (2) is subjected to a second gradient elution with a mobile phase and then processed to obtain the target products: myricetin-3-O-(2″-galloyl)-α-L-rhamnoside monomer and myricetin-3-O-(4″-galloyl)-α-L-rhamnoside monomer.
The present invention discloses a server load prediction method based on deep learning, collecting the trend change of server load long series, and utilizing server load periodic information to establish a deep neural network prediction model to optimize peak load prediction. The present invention provides a method for improving the accuracy of neural network prediction by combining periodic information, long-term trend information, and short-term time series information, and demonstrates superiority over traditional methods in the peak load section. The method of the present invention can effectively improve prediction accuracy, provide more accurate scheduling and evacuation decision-making basis for cloud service providers, thereby reducing the redundant equipment required to ensure high reliability, reducing the operating costs of cloud service providers, and reducing the rental expenses of cloud service tenants.
H04L 41/16 - Arrangements for maintenance, administration or management of data switching networks, e.g. of packet switching networks using machine learning or artificial intelligence
G06N 3/0442 - Recurrent networks, e.g. Hopfield networks characterised by memory or gating, e.g. long short-term memory [LSTM] or gated recurrent units [GRU]
G06N 3/084 - Backpropagation, e.g. using gradient descent
H04L 43/0817 - Monitoring or testing based on specific metrics, e.g. QoS, energy consumption or environmental parameters by checking availability by checking functioning
7.
AN ADAPTIVE PERSONALIZED FEDERATED LEARNING METHOD SUPPORTING HETEROGENEOUS MODEL
The present invention discloses an adaptive personalized federated learning method supporting heterogeneous model, based on the use of models with different structures by various participants supporting federated learning, learning the dynamic weight used for model ensemble and introducing optimization objectives for model integration in the process of training model parameters, realizing highly accurate personalized federated learning with heterogeneous and self adaptive data, the participants are enabled to benefit from federated learning in scenes with heterogeneous data at different levels. The adaptive personalized federated learning method of the present invention does not need to introduce new hyper parameters, and can be conveniently deployed in the existing federated learning system; comparing with the traditional personalized federated learning method, the present invention has stronger adaptability.
Disclosed in the present invention is a multi-objective hot rolling quality detection method based on progressive layered extraction. The present invention comprises the following steps: firstly, collecting hot rolling production process data, and determining a plurality of hot rolling quality detection parameters corresponding to the hot rolling production process data, so as to construct a hot rolling production data set; then performing data preprocessing on the hot rolling production data set to obtain a preprocessed data set; then training, on the basis of the preprocessed data set, a multi-objective network based on progressive layered extraction to obtain a multi-objective hot rolling quality detection model; and finally, inputting preprocessed hot rolling production data to be predicted into the multi-objective hot rolling quality detection model, outputting a multi-objective hot rolling quality detection result, and calculating predicted values of the plurality of hot rolling quality detection parameters on the basis of the multi-objective hot rolling quality detection result. According to the present invention, by performing weighted fusion on features of different quality detection parameters, regularization is achieved, thereby improving the accuracy and anti-interference performance of hot rolling quality detection.
A (Sm,T)(Fe,M)12 alloy is provided, where Sm is samarium element; Fe is iron element; T is selected from the group consisting of Y, Gd, Zr, Nd, Pr, Ce and a combination thereof; and M is selected from the group consisting of Ti, Cr, Mn, Mo, Si, Al, Ga, Co, V and a combination thereof. A high-throughput method of preparing the (Sm,T)(Fe,M)12 alloy based on a diffusion multiple is further provided, in which a can, a cover, and metal strips with desired sizes are prepared, and the metal strips are arranged and loaded in the can. Then the can is subjected to vacuum electron beam welding and hot isostatic pressing to obtain the diffusion multiple, which is cut into slices, and subjected to tube sealing and heat treatment to obtain the desired (Sm,T)(Fe,M)12 alloy.
A method for preparing nanomaterial macroscopic composites through substrate heating and solvent evaporation is provided, and the method includes setting a substrate, and preparing a reaction precursor solution required for the synthesis of nanomaterials; evenly dropping a small volume of the precursor solution on/in the substrate; performing a heating method to make the substrate generate a heat and transferring the heat to the precursor solution on/in the substrate; after a period of time, terminating the heating of the substrate to finish the synthesis, removing and cleaning the substrate, thus obtaining corresponding nanomaterial macroscopic composites.
B01J 20/30 - Processes for preparing, regenerating or reactivating
B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
Provided are compounds of formula (1) and/or formula (2), and/or pharmaceutically acceptable salts thereof, and/or racemic mixtures, hydrates, solvates, prodrugs, enantiomers, diastereomers and tautomers thereof, belonging to the technical field of medicines. Also provided are pharmaceutical compositions containing the compounds of formula (1) and/or formula (2), and the uses of the compounds of formula (1) and/or formula (2) and/or the pharmaceutically acceptable salts thereof, and/or the racemic mixtures, hydrates, solvates, prodrugs, enantiomers, diastereomers and tautomers thereof, and/or the pharmaceutical compositions in preparing histone deacetylase inhibitors and drugs used for the treatment and/or prevention of diseases responsive to histone deacetylases.
C07D 491/048 - Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
C07D 491/153 - Ortho-condensed systems the condensed system containing two rings with oxygen as ring hetero atom and one ring with nitrogen as ring hetero atom
A61K 31/4355 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
RESEARCH INSTITUTE OF CHINA SOUTHERN POWER GRID CO., LTD. (China)
Inventor
Liu, Zhanning
Diao, Ruisheng
Zheng, Waisheng
Zhou, Baorong
Li, Shiyang
Mao, Tian
Yao, Wenfeng
Abstract
1212rippleR_lossrr; and on the basis of an NSGA-II algorithm model, using said parameters as decision variables, performing iterative optimization on the plurality of objective functions according to the boundary constraints so as to obtain a parameter solution set of optimal solutions, and selecting a group of typical values from the parameter solution set as optimization solutions. The present invention can significantly improve the filtering effect and the weak grid resistance of filters.
Provided are an indazole derivative or a pharmaceutically acceptable salt thereof and the use thereof. Specifically provided is a novel indazole derivative, which has an inhibition function on an ROCK kinase, can be used as an ROCK kinase inhibitor, has a novel structure type, and can be used as a potential therapeutic drug for various diseases, such as inflammatory diseases, autoimmune diseases, fibrotic diseases, transplantation rejection, diseases related to hypersecretion of IL-17, IL-21 and/or IL-23, ocular diseases, cardiovascular and cerebrovascular diseases, tumor metastasis, central nervous system diseases, diabetic nephropathy and skin diseases.
C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 31/513 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
14.
LARGE-FIELD-OF-VIEW PANORAMIC IMAGING SYSTEM BASED ON REUSED REFLECTING SURFACE
A large-field-of-view panoramic imaging system based on a reused reflecting surface. The system comprises a panoramic annular head unit, a subsequent lens group and an image sensor, which are coaxially mounted, wherein a rear reflecting surface (A3) of a second lens (PAL2) comprised in the panoramic annular head unit can simultaneously reflect light rays from a glass side and an air side to respectively form a forward field-of-view channel and a backward field-of-view channel; an object-side surface of a first lens (RL1) comprised in the subsequent lens group has a central circular area (S1) and an outer-ring circular ring area (S2); and the central circular area (S1) and the outer-ring circular ring area (S2) are two even aspheres having different surface type parameters, and respectively deflect light rays from the forward field-of-view channel and the backward field-of-view channel. Therefore, the large-field-of-view panoramic imaging system can realize an imaging field-of-view range of (35°-120°) × 360°.
The invention discloses a multi-cell digital light processing printer and method controlled by “light field-magnetic field” coupling. The invention couples a magnetic field generating device and a light curing device, and uses the magnetic field to control the material changing of microspheres carrying different cells and different magnetic contents in the vat, so that the material changing process and the printing process are in parallel, and the printing efficiency is improved; at the same time, a single vat is used for non-contact material changing, which reduces cross-contamination and can produce multi-cell biological structures with “high accuracy, high efficiency, and high cell activity”.
B29C 64/165 - Processes of additive manufacturing using a combination of solid and fluid materials, e.g. a powder selectively bound by a liquid binder, catalyst, inhibitor or energy absorber
Provided is a high-efficiency expression vector of a circular ribonucleic acid (circRNA). The high-efficiency expression vector is an expression framework with a total length of only 173 bp and having a nucleotide sequence shown in SEQ ID NO: 1, and includes an upstream frame sequence of 92 bp, a downstream frame sequence of 75 bp, and a restriction site EcoR I located between the upstream and downstream frame sequences for inserting a gene to be circularized. In the present disclosure, the high-efficiency expression vector of a circRNA can enable an exogenously-inserted sequence to efficiently express the circRNA, thus providing an efficient expression tool for obtaining the circRNA. On the premise of ensuring efficient circularization of the circRNA, lengths of upstream and downstream flanking sequences required for the circularization have been highly optimized to further reduce the complexity of splicing by-products caused by the flanking sequences.
C12N 15/66 - General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligationUse of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
A device for generating laser with ultra-narrow-linewidth includes an optical self-injection locking loop and an ultra-stable cavity phase-locked loop. The optical self-injection locking loop improves the quality factor of the laser resonator to narrow the linewidth. The ultra-stable cavity phase-locked loop locks the phase of the optical signal in the optical self-injection, synchronizing the laser frequency with the optical resonator. Through feedback control of the laser's driving current, it further reduces the laser's frequency noise and enhances the linewidth narrowing rate. Additionally, the ultra-stable cavity phase-locked loop provides stable control of the laser frequency, preventing mode hopping caused by laser frequency drift, thereby improving system stability. Therefore, this device can provide a stable narrow-linewidth laser source for applications in fiber optic communication, lidar, industrial device processing, and medical fields.
H01S 3/10 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
H01S 3/08 - Construction or shape of optical resonators or components thereof
H01S 3/0941 - Processes or apparatus for excitation, e.g. pumping using optical pumping by coherent light of a semiconductor laser, e.g. of a laser diode
A method for computed tomography imaging and reconstruction based on learning, which measures the scene density distribution in an illumination multiplexing manner. The light source(s) for imaging emit(s) light according to the intensity obtained by pre-learning, and the light from different directions is absorbed and attenuated by the scene and reaches a sensor. The measured values are calculated and reconstructed to obtain the density information of the scene. The illumination intensity and reconstruction algorithm are learned by a neural network. In this method, the CT imaging process is modeled as a linear fully connected layer, and the weight corresponds to the illumination intensity of the light source for imaging; the reconstruction algorithm is modeled as a nonlinear neural network, which can be optimized according to the characteristics of scanning geometry.
The present disclosure provides a method and system for evaluating carbon sequestration of duckweed for a rice-duckweed symbiotic system, and a device. The method includes: after rice harvesting, collecting duckweed information in a rice-duckweed symbiotic system using spectrum scanning and laser-point cloud techniques, and determining a duckweed volume based on the duckweed information; determining a duckweed biomass in the rice-duckweed symbiotic system based on the duckweed volume; and estimating carbon sequestration of duckweed from the duckweed biomass using an artificial neural network algorithm, or estimating the carbon sequestration of duckweed from the duckweed biomass by a duckweed carbon sequestration estimation formula. The present disclosure may allow for flexible estimation of carbon sequestration of duckweed based on information such as agronomic management on rice, soil, and climate, and provide a good technical support for the management and application of duckweed in paddy fields.
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
20.
USE OF COTTON FIBER STRENGTH TRAIT-ASSOCIATED GHEIF5A GENE
A use of a cotton fiber strength trait-associated GhEIF5A gene. In tetraploid Gossypium hirsutum TM-1, the cotton fiber strength trait-associated GhEIF5A gene has a cDNA sequence of SEQ ID NO: 1 and a genome sequence of SEQ ID NO: 2; the GhEIF5A gene is regulated by a neighboring SNP site, and a base at the SNP site is mutated from T to C; and the fiber strength of the mutated genotype is significantly higher than that of a wild-type genotype. The gene has important research value and application prospects in efficiently identifying high-fiber-strength Gossypium hirsutum varieties, improving cotton quality traits, and breeding novel high-fiber-strength cotton varieties.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
C12N 15/29 - Genes encoding plant proteins, e.g. thaumatin
C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
21.
5-AMINO-1-ALKYL-1H-1,2,3-TRIAZOLE-4-FORMAMIDE COMPOUND, AND PREPARATION AND USE THEREOF
Disclosed in the present invention are a 5-amino-1-alkyl-1H-1,2,3-triazole-4-formamide compound having a structural general formula as shown in formula (1), a pharmaceutically acceptable salt thereof, or a racemic mixture, hydrate, solvate, prodrug, enantiomer, diastereomer, and tautomer thereof. Also disclosed in the present invention are a pharmaceutical composition containing the compound of formula (1), and a use of the compound of formula (1), the pharmaceutically acceptable salt thereof, or the racemic mixture, hydrate, solvate, prodrug, enantiomer, diastereomer, and tautomer thereof, or the pharmaceutical composition in preparation of a drug for treatment of diseases responsive to regulation of an ion channel function.
C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C07D 409/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
Disclosed is a system comprising an artificial enzyme, a probiotic bacteria and a linker to conjugate the artificial enzyme and probiotic bacteria. Further disclosed are compositions comprising the said system and the uses thereof.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 47/62 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
23.
METHOD OF CONSTRUCTING WATER SUPPLY PIPELINE LEAKAGE IDENTIFICATION MODEL BASED ON DEEP LEARNING AND APPLICATION THEREOF
Innovation Center of Yangtze River Delta, ZJU (China)
Zhejiang University (China)
Inventor
Shen, Yonggang
Zhang, Tuqiao
Yu, Tingchao
Yu, Hongliang
Abstract
A method of constructing a water supply pipeline leakage identification model based on deep learning and an application thereof are provided, which relate to the technical field of nondestructive detection and positioning of municipal water supply pipeline leakage. By extracting Mel-frequency cepstral coefficient of leakage sound signals as a basis for distinguishing pipeline leakage, a neural memory network is introduced to learn leakage features and establish a leakage feature neural network model, and the features of a signal of a point to be detected are input into the model to determine whether the point leaks, so as to realize accurate positioning of the pipeline leakage position.
G01M 3/24 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using infrasonic, sonic, or ultrasonic vibrations
G10L 25/24 - Speech or voice analysis techniques not restricted to a single one of groups characterised by the type of extracted parameters the extracted parameters being the cepstrum
G10L 25/30 - Speech or voice analysis techniques not restricted to a single one of groups characterised by the analysis technique using neural networks
24.
BIOCHAR-ENHANCED GRASS BLANKET FOR REMEDIATING CONTAMINATED SEDIMENT AND PREPARATION METHOD THEREOF, AND METHOD FOR REMEDIATING CONTAMINATED SEDIMENT
INNOVATION CENTER OF YANGTZE RIVER DELTA, ZJU (China)
ZHEJIANG UNIVERSITY (China)
Inventor
Zhu, Liang
Wei, Lecheng
Chen, Haoyu
Jiang, Binbin
Xu, Xiangyang
Abstract
The disclosure relates to the technical field of polluted sediment remediation, and particularly relates to a biochar-enhanced grass blanket for remediating contaminated sediment and a preparation method thereof, and a method for remediating contaminated sediment. In the disclosure, the grass blanket for remediating contaminated sediment prepared by the method can not only efficiently absorb pollutants released from the contaminated sediment but also facilitate the entry of the root system of submerged plants into the contaminated sediment simultaneously, thereby improving the survival rate of the submerged plant and effectively ameliorating the matrix of the contaminated sediment.
The present invention discloses a separation membrane based on a reactive support layer, a preparation method and an application, and belongs to the technical field of water treatment membranes. The preparation method includes: (1) subjecting a porous support membrane to an amino grafting reaction to prepare a reactive support membrane; and (2) subjecting an aqueous phase solution and an oil phase solution containing a multi-membered acyl chloride oil phase monomer to interfacial polymerization on the reactive support membrane to prepare a separation membrane based on a reactive support layer; where an aqueous phase monomer in the aqueous phase solution is a semi-aromatic amine or an aromatic amine. In the present invention, the porous support membrane is subjected to the amino grafting reaction to obtain the reactive support membrane, and the interface polymerization is carried out on a surface of the reactive support membrane. Due to the reactive support membrane, a structure of a formed polyamide separation layer can be changed, thereby improving the water permeability of a polyamide separation membrane and maintaining an ion retention property or the ion selectivity thereof. The method of the present invention has the advantages of a simple process, low requirements for equipment and convenience in industrial production, and the prepared high-performance separation membrane has a wide application prospect in the field of water treatment.
A method for detecting diaper wetness based on a ratio signal technology comprises: sending a frequency-modulated continuous wave signal to a diaper through a radar device to obtain a transmission signal ST(t) and a return signal SR(t); detecting a static environment factor and a dynamic environment factor, and obtaining continuous radar snapshots; eliminating interference of environmental factors by using a filtering template based on the continuous radar snapshots and object respiration; obtaining an outline of the diaper by using wavelet synchronous compression transformation, and dividing into a training sample set and a testing sample set; and inputting the training sample set and the test sample set into a heuristic mobility network for training until a loss function is converged, obtaining the trained heuristic mobility network, and obtaining diaper wetness of the test sample set.
The present disclosure discloses a method of determining efficiency of increasing a soil carbon sink based on green manure returning to fields and a system thereof. The method includes: determining green manure biomass of a target farmland based on an unmanned aerial vehicle lidar technology during a fallow period of the target farmland before green manure is turned over; calculating carbon biomass of the target farmland based on the green manure biomass; calculating microbial soil carbon pump efficiency and mineral carbon pump efficiency after the green manure of the target farmland is turned over; and determining a soil carbon sink effect of turning over green manure on the target farmland according to the carbon biomass, the microbial soil carbon pump efficiency and the mineral carbon pump efficiency. The present disclosure realizes the quantitative calculation of efficiency of increasing the soil carbon sink of green manure.
The present invention relates to the technical field of organic semiconductors, and disclosed are a fullerene single crystal thin film, and a preparation method therefor and the use thereof. The preparation method comprises the following steps: 1) mixing fullerene and a solvent to form a mixed solution; and 2) crystallizing and growing fullerene in the mixed solution on the surface of a substrate by using a solution shearing method, so as to obtain a fullerene single crystal thin film. A large-area fullerene single crystal thin film is prepared by means of directly regulating and controlling the nucleation density of fullerene at the three-phase line and utilizing the continuous movement of the three-phase line. The fullerene single crystal thin film has the advantages of uniform orientation, high uniformity and high coverage, and in addition has good electron transport performance and can satisfy application requirements of the photoelectric field.
C30B 7/00 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
29.
METHOD FOR OPTIMIZING SAMPLING TRAJECTORY OF MOLECULAR EXCHANGE MAGNETIC RESONANCE MEASUREMENT, AND MOLECULAR EXCHANGE MAGNETIC RESONANCE MEASUREMENT METHOD AND APPARATUS
Disclosed in the present invention is a method for optimizing a sampling trajectory of molecular exchange magnetic resonance measurement. The method comprises: (1) determining the number of physiological/physical parameters of a molecular exchange system and a corresponding range, and generating a data set of simulated physiological/physical parameters; (2) determining a molecular exchange magnetic resonance measurement method, and setting collection parameters; (3) constructing an end-to-end unified network model, which comprises a sampling trajectory optimization network, a noise signal generation network and a parameter estimation network; and (4) using the simulated physiological/physical parameters as an input for training, and completing the training until the network converges, so as to obtain an optimized sampling trajectory and a corresponding parameter estimation network. Further disclosed in the present invention are a molecular exchange magnetic resonance measurement method and apparatus. The method for optimizing a sampling trajectory of molecular exchange magnetic resonance measurement that is provided in the present invention improves the efficiency and accuracy for estimating physiological/physical parameters, and can be applied to different molecular exchange magnetic resonance measurement methods.
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
G01R 33/50 - NMR imaging systems based on the determination of relaxation times
30.
Microgrid self-triggering control method and system for resisting FDI attacks
Hainan Research Institute of Zhejiang University (China)
Zhejiang University (China)
Inventor
Chen, Yulin
Qi, Donglian
Huang, Xing
Yan, Yunfeng
Weng, Shenjun
Wang, Xianbo
Abstract
A microgrid self-triggering control method and system for resisting FDI attacks is provided. The method includes the following steps: S1: adopting primary control based on droop control for a microgrid; S2: designing a secondary control strategy of the microgrid, where the secondary control strategy includes frequency recovery and fair distribution of active power; and S3: designing a microgrid distributed self-triggering control method of a hash encryption method after considering the condition that the FDI attacks are injected into a secondary control communication link, so as to resist false malicious data in the microgrid and achieve secondary control. According to the microgrid self-triggering control method and system, a distributed secondary control target of the microgrid is achieved even under the FDI attacks, the injected malicious data can be quickly detected and eliminated, and the distributed secondary control communication network of the microgrid can be protected.
A full-particle-size respiratory droplet sampling system. Airflow exhaled from a human body directly enters a droplet collection device (1); the droplet collection device (1) is communicated with a sampling flow rate adjustment device (5) by means of a droplet bent collection device (2) and a droplet particle size screening device (3); the droplet collection device (1) is communicated with a droplet particle size measurement device (6); the droplet collection device (1), the droplet bent collection device (2) and the droplet particle size screening device (3) are all arranged in a sampling chamber air supply and filtering device (4); under the action of the sampling flow rate adjustment device (5), the airflow passes through a metal shell (12), an impact guide member (21), a bent redirection member (23) and a vertical transition pipeline (24) and then enters an impactor (31); a laser component (63) and a camera (62) are used in cooperation; and a droplet particle size distribution is obtained by means of processing of a computer (65).
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
B01D 50/20 - Combinations of devices covered by groups and
G01N 15/02 - Investigating particle size or size distribution
The present invention relates to the field of biomedicines. Disclosed are an intervention target for advanced fibrosis of an ischemic heart disease and a use thereof. In the present invention, it was found that a CD248 protein is only specifically and highly expressed in cardiac fibroblasts in an ischemic injury area, and is expressed at lower levels in other normal tissue cells, and therefore, the CD248 protein can be used as an intervention target for advanced fibrosis of an ischemic heart disease to effectively inhibit excessive cardiac fibrosis, and the safety is high. According to the present invention, an RNA fragment, a monoclonal antibody and a CAR-T cell targeting CD248 are prepared; the RNA fragment can inhibit CD248 gene expression; the monoclonal antibody has good affinity to the CD248 protein, and can effectively inhibit the activation of fibroblasts; and the CAR-T cell has better infiltration into a heart ischemia injury area, and can kill CD248+ fibroblasts.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
A61K 39/00 - Medicinal preparations containing antigens or antibodies
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
33.
LEARNING-BASED COMPUTED TOMOGRAPHY IMAGING AND RECONSTRUCTION METHOD
The present invention provides a learning-based computed tomography (CT) imaging and reconstruction method, for use in measuring scene density distribution by means of illumination reuse. During imaging, a light source emits light on the basis of the intensity obtained by pre-learning, light from different directions is absorbed and attenuated by a scene and then reaches a sensor, and computational reconstruction is performed on measurement values to obtain density information of the scene. Luminous intensity and a reconstruction algorithm are obtained by means of neural network learning. In the method, a CT imaging process is modeled as a linear fully-connected layer, and a weight corresponds to the luminous intensity of the light source during imaging; the reconstruction algorithm is modeled as a nonlinear neural network, and targeted optimization can be performed on the basis of the characteristics of scan geometry. According to the method, the amount of acquisition data required is small, and the computational reconstruction does not require a strong priori assumption, so that efficient and high-quality CT acquisition and reconstruction is achieved, and thus the method can be applied to three-dimensional reconstruction of a high-speed dynamic scene.
Disclosed are a mixed traffic flow-oriented vehicle eco-driving control method and an electronic device. The method comprises: on the basis of shock wave evolution theory, calculating a congestion wave speed and a dissipation wave speed at an intersection, to obtain a farthest queuing point position of an intersection downstream of a connected and autonomous vehicle and a formation moment thereof, and predicting a time and vehicle status when the connected and autonomous vehicle passes a stop line; predicting longitudinal acceleration of a manual vehicle according to a risk field model, to acquire a predicted trajectory of the manual vehicle; constructing and solving an optimal ecological reference trajectory planning model for the connected and autonomous vehicle, to obtain an acceleration curve of the connected and autonomous vehicle, and acquire an ecological reference trajectory of the connected and autonomous vehicle; on the basis of predicted trajectories of manual vehicles in front of and behind the connected and autonomous vehicle and the risk field model, setting a risk factor, constructing a tracking target on the basis of the risk factor and the ecological reference trajectory, and using a model predictive control solution, to obtain a control input for the connected and autonomous vehicle.
A hydrogen fueling station based on low-temperature and high-pressure staged hydrogen storage, comprising: a liquid hydrogen storage tank (1); hydrogen storage containers (6), wherein n hydrogen storage containers (6) are provided, n≥2, and the hydrogen storage containers (6) are low-temperature and high-pressure hydrogen storage containers; booster pumps (2, 3) and high-pressure carburetors (4, 5), arranged between the liquid hydrogen storage tank (1) and the hydrogen storage containers (6), wherein the temperature value of hydrogen stored in each hydrogen storage container (6) is Tn, and the highest pressure value is Pn, wherein when n=2, T1
Disclosed are a Gossypium hirsutum low-density liquid phase chip based on targeted capture sequencing and the use thereof. The low-density chip comprises 908 SNP sites, including 329 sites significantly associated with important agronomic traits such as fiber quality, yield, and disease resistance of Gossypium hirsutum, 14 common sites for plant transgene detection, and 565 other sites. The chip is suitable for the use in transgenic ingredient detection, resource evaluation, genetic identification, and seed purity identification in Gossypium hirsutum varieties, and genetic improvement of major agronomic traits in Gossypium hirsutum varieties.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
37.
GLUCOSE-RESPONSIVE MOLECULAR CONNECTOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Provided in the present invention is a glucose-responsive molecular connector, and a preparation method therefor and the use thereof. A brand-new glucose-responsive molecular connector is formed by the esterification of a phenylboronic acid analogue and a 1,3-diol structure. The compound can be directly biolinked to insulin by amidation and has a very good glucose-responsive function, wherein glucose at a high concentration competes with the 1,3-diol structure for binding to phenylboronic acid, so that the solubility of insulin is increased and the release of insulin is promoted, and when the glucose is at a low concentration, only a small amount of insulin is in a free state, thereby reducing the occurrence of hypoglycemia. The compound achieves the glucose response of insulin by means of a brand-new mechanism, causing the glucose response effect more sensitive. Moreover, the compound has the advantages of simple structure, being easy to prepare and low cost, and has great clinical application value.
A scour protective device around piles with bidirectional flow power generation. A smooth water flow channel is formed by guide walls and baffle walls. A power generation device is placed at smallest section of the channel. The piles are wrapped by smooth normal distributional surfaces, and the water flow is divided to outsides of normal distributional surfaces. The guide walls at both ends are tangent to eliminate downflow of the incident flow surface and horseshoe vortex around the piles, to avoid local scour. The tidal current is introduced into the channel to accelerate, and contraction panels are further compressed to realize hydropower generation and improve the utilization rate of tidal energy. The swing door makes hydraulic turbines rotate in the same direction when the tide rises and falls, realizing reliable bidirectional hydropower generation. The system provides efficient and environmentally friendly renewable power for bridge lighting, signal lights and vessels.
E02B 17/00 - Artificial islands mounted on piles or like supports, e.g. platforms on raisable legsConstruction methods therefor
E02D 31/00 - Protective arrangements for foundations or foundation structuresGround foundation measures for protecting the soil or the subsoil water, e.g. preventing or counteracting oil pollution
H02K 7/18 - Structural association of electric generators with mechanical driving motors, e.g.with turbines
39.
Landslide model test devices and methods for realizing multi-variable synchronous monitoring
The present disclosure relates to the technical field of landslide hazard model tests, and in particular to a landslide model test method and device for realizing multi-variable synchronous monitoring. In the test device, a soil slope simulation unit is configured to pile up a soil slope and simulate different inclinations of the slope. A rainfall simulation unit is configured to simulate rainfall of different intensities and induce a landslide. A runoff-seepage separation unit is configured to realize separation of runoff from seepage of the slope under the effect of rainfall. A monitoring module is configured to monitor runoff and seepage flow rates of the slope, changes in water content and pore water pressure within the slope, and a morphological change of the slope under the effect of rainfall, to obtain a mechanism of rainfall-induced landslide deformation and damage based on changes in the flow rate.
An endogenous chimeric antigen receptor (ECAR) has an antigen-binding domain that is an endogenous protein molecule. The engineered immune cells expressing the ECAR can kill a variety of cells specifically and selectively.
The present invention provides a real-time fluorescence loop-mediated isothermal nucleic acid amplification detection method. On the basis of a universal loop-mediated isothermal amplification system, one or more of inner primers (FIP/BIP) and loop primers (LF/LB) are labeled with a fluorescent group and a quenching group. The fluorescent group and quenching group are attached at any position of the primer except the 3' end. The primer is used for nucleic acid amplification, and fluorescence generated by interaction between the fluorescent group and the quenching group is detected, to achieve nucleic acid amplification detection.
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
42.
PHOTOELECTRIC TERAHERTZ HYPERSPECTRAL IMAGING SYSTEM AND METHOD BASED ON SWEPT-FREQUENCY DUAL-COMB
Disclosed in the present invention are a photoelectric terahertz hyperspectral imaging system and method based on a swept-frequency dual-comb. The system comprises: a swept-frequency laser, a distributed feedback laser, a dual-comb generation module, a coupling beam splitter, a spectrum analyzer, a variable optical attenuator, a terahertz mixer, an off-axis parabolic mirror group, a zero bias detector, an electric amplifier and a signal analyzer, wherein the tunable distributed feedback laser is mixed with electro-optical dual-comb light to generate a swept-frequency terahertz dual-comb signal, point-by-point imaging of an object is realized by means of grid scanning, the swept-frequency dual-comb breaks the trade-off between a spectral bandwidth and a frequency resolution in a dual-comb system, and a frequency resolution of 50 MHz is achieved under a spectral bandwidth ranging from 220 GHz to 320 GHz. Scanning dual-comb terahertz imaging has a higher data collection rate, a more flexible spectral tuning range and a higher frequency resolution at room temperature, and the system is flexible and configurable, and has a simple structure and a high detection efficiency.
G01N 21/3581 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared lightInvestigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using Terahertz radiation
G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
43.
Flexible dynamic capturing system for underwater moving carrier
The present invention discloses a flexible dynamic capturing system for an underwater moving carrier, including a shell, a front-end flexible guide apparatus, at least one tail flexible hand clamping and fastening apparatus, and a bottom retracting apparatus fastened in the shell. The front-end flexible guiding apparatus includes several flexible arms, the several flexible arms are fastened on a first rigid base in a circumferential array. The flexible arms can bend to an inner side and outer side of a circumference respectively when driven. Each tail flexible hand clamping and fastening apparatus includes several flexible claws, and the several flexible claws are divided into two groups and fastened on a second rigid base. When the flexible claws are driven, the two groups of flexible claws can bend and wind relative to each other. The bottom retracting apparatus implements lifting or lowering of the front-end flexible guide apparatus and the tail flexible hand clamping and fastening apparatus. The flexible dynamic capturing system for the present invention can capture underwater moving carriers of different diameters, and can be retracted and stored with a compact volume.
A preparation method of a misch-metal permanent magnetic material based on sintering and multi-step diffusion is provided. A sintered substrate magnet is prepared by induction melting, strip casting, hydrogen decrepitation, jet milling, magnetic alignment, isostatic pressing and sintering. A first diffusion source and a second diffusion source are prepared, where the first diffusion source is a light rare-earth metal or its alloy, and the second diffusion source is a light-heavy rare-earth combination or its alloy. The sintered substrate magnet is sequentially subjected to a first vacuum diffusion with the first diffusion source and a second vacuum diffusion with the second diffusion source. The resultant product is subjected to low-temperature tempering to give the desired misch-metal permanent magnetic material.
The present invention relates to a polypeptide for inhibiting TRPM8 and a use thereof. Specifically, the present invention provides a polypeptide or a pharmaceutically acceptable salt thereof. The polypeptide of the present invention has an excellent inhibitory effect on TRPM8 and is used for preventing and treating TRPM8-related diseases.
A debridement device for human body pathological tissue, comprising an insertion tube, a rotary cutting head and an operating handle. The insertion tube comprises an inner tube and an outer tube fitted outside the inner tube; an aspiration cavity is formed in the inner tube, and an irrigation cavity is formed between the inner tube and the outer tube; the rotary cutting head comprises a housing and a rotary cutting blade arranged in the housing; the interior of the housing is communicated with the aspiration cavity; a rotary cutting opening exposing the rotary cutting blade is formed on the housing; a notch corresponding to the rotary cutting opening is formed on the outer tube; the operating handle is connected to the insertion tube and the rotary cutting head so as to control the rotary cutting blade to cut human tissue at the rotary cutting opening, suction debris by means of the aspiration cavity, and use the irrigation cavity to flush the position where the rotary cutting head is located. The device can carry out both rotary cutting and aspiration on human body pathological tissue, reduce residues of necrotic tissue, effectively protect surrounding normal tissues and blood vessels, reduce the possibility that a patient requires repeated surgery, and improve the efficiency, effect and safety of minimally invasive therapy.
A light scattering patch device and preparation method thereof is disclosed. The light scattering patch device is composed of a patch, an air gap, and a tapered optical fiber; the patch is a transparent patch; a refractive index of the patch is greater than a refractive index of a biological tissue; a tip, a tapered transition zone and a partial unstretched zone of the tapered optical fiber are embedded in the patch, and the air gap is formed between the tip and the tapered transition zone of the tapered optical fiber and the patch. The method of preparing the light scattering patch device comprises: first preparing the tapered optical fiber, then performing hydrophobic modification on the surface of the tapered optical fiber; placing the tapered optical fiber in an uncured polymer and curing the uncured polymer, and pulling the unstretched part; connecting the unstretched part of the tapered optical fiber.
A fibroblast activation protein (FAP) targeting chimeric antigen receptor macrophage and its construction method and application. The expression of FAP increases in senescent cells of various senescent diseases. Immune cells, especially macrophages, specifically eliminates senescent cells after expressing chimeric antigen receptor recognizing FAP protein, thereby reducing the pathogenic effect of senescent cells. Macrophages expressing the FAP chimeric antigen receptor can undergo M2-type polarization, which do not produce inflammatory factors to deteriorate age related diseases, have good infiltration ability to tissues with dense matrix, do not induce graft-versus-host disease and have high recognition efficiency of senescent cells and good phagocytic effect. This provides a new idea for preparing reagents for eliminating senescent cells, which have wide potential in practical application.
A61K 35/15 - Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cellsMyeloid precursor cellsAntigen-presenting cells, e.g. dendritic cells
A preparation method for a large crystal region high crystallinity carbonaceous fiber, where a wet spinning method is mainly used to assemble graphene oxide and other polymer materials in liquid phase, a two-dimensional graphene oxide sheet performs a “template orienting effect” on polymer molecules, making the directional crystallization of polymer molecules, resulting in fiber with high orientation and crystallinity. Graphene sheet catalyzes pyrolyzed molecules through a “graphitization inducing effect” to directionally generate graphene-like carbon layers after following high temperature treatment, thereby promoting stacking behavior of graphene sheets, and a composite carbonaceous fiber with an optimal crystallinity is prepared. The graphene fiber material prepared by the present method has characteristics of low cost, high crystallinity and high performance, and can be applied to a field of lightweight structural materials. The present invention is a high crystallinity graphene fiber material with two-dimensional induction effect and a preparation method for the same.
D01F 9/20 - Carbon filamentsApparatus specially adapted for the manufacture thereof by decomposition of organic filaments from polyaddition, polycondensation or polymerisation products
An online indirect measurement method for pitching and yawing moments of a wind or tidal current turbine is provided. The method uses an online indirect measurement system including an incoming flow velocity measurement module, a generator rotation speed measurement module, a pitch angle measurement module, and a computer; the incoming flow velocity measurement module measures the flow velocity of the rotor center; the generator rotation speed measurement module measures the generator rotation speed; the pitch angle measurement module measures the pitch angle of each blade; the computer receives signals of flow velocity, generator rotation speed, and pitch angle, obtains the pitching moment and yawing moments of the turbine via an online calculation, and displays and stores the measured and calculated data in real time.
Disclosed in the present invention is a venous closure device, comprising a first closure device and a second closure device, each of which comprises a catheter, a guide wire, a balloon and a handle portion, wherein the guide wire is arranged inside the catheter, the balloon and the handle portion are arranged outside the catheter, the balloon is arranged at a front-end position of the catheter, the handle portion is arranged at a rear-end position of the catheter, the part of the second closure device other than the handle portion has a smaller diameter than the guide wire of the first closure device, and the part of the second closure device other than the handle portion can pass through the catheter of the first closure device. According to the present invention, the venous closure device can assist an operator to perform effective laparoscopic blood occlusion of hepatic vein or inferior vena cava to reduce hemorrhage during operation of laparoscopic hepatectomy, so as to reduce the probability of laparotomy following a laparoscopic operation, thereby ensuring the patient's safety, and can also push tumor emboli from the inferior vena cava or the hepatic vein into an operative region of hepatectomy, so as to reduce the probability of vascular metastasis of tumor emboli caused by the surgical operation, thereby improving the efficiency, effect and safety of laparoscopic treatment.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A multi-energy-field induced atomic scale numerical control machining device and method in an environmental atmosphere, which belong to the field of atomic and close-to-atomic scale extreme manufacturing. The device comprises an electromagnetic shielding cavity (17) and a control mechanism, wherein an environmental cavity (16) is disposed inside the electromagnetic shielding cavity (17), a workpiece placement platform is disposed at the bottom of the environmental cavity (16), a nano-tool (11) driven by a nano-tool actuating mechanism is a disposed at the top thereof, and the electromagnetic shielding cavity (17) is provided with an air inlet and an air outlet which are in communication with the environmental cavity (16); and the control mechanism is used for controlling the workpiece placement platform and the nano-tool actuating mechanism, and for applying energy fields, including a force field, a temperature field, an electric field, a light field and a magnetic field. Problems such as conventional atomic layer deposition and etching technology relying on a mask to obtain local features and not allowing for atomic scale controllable manufacturing, and scanning tunnel microscope atomic manipulation technology relying on an ultrahigh vacuum and an ultralow-temperature environment, only being used for specific materials, and having a low manipulation efficiency are solved. The present invention has the advantages of atomic scale precision, high efficiency, low costs, good universality, etc.
B81C 1/00 - Manufacture or treatment of devices or systems in or on a substrate
B81C 3/00 - Assembling of devices or systems from individually processed components
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
H01L 21/302 - Treatment of semiconductor bodies using processes or apparatus not provided for in groups to change the physical characteristics of their surfaces, or to change their shape, e.g. etching, polishing, cutting
H01L 21/30 - Treatment of semiconductor bodies using processes or apparatus not provided for in groups
H01L 21/18 - Manufacture or treatment of semiconductor devices or of parts thereof the devices having potential barriers, e.g. a PN junction, depletion layer or carrier concentration layer the devices having semiconductor bodies comprising elements of Group IV of the Periodic Table or AIIIBV compounds with or without impurities, e.g. doping materials
H01L 21/04 - Manufacture or treatment of semiconductor devices or of parts thereof the devices having potential barriers, e.g. a PN junction, depletion layer or carrier concentration layer
H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
H01L 21/00 - Processes or apparatus specially adapted for the manufacture or treatment of semiconductor or solid-state devices, or of parts thereof
G01Q 60/00 - Particular types of SPM [Scanning-Probe Microscopy] or apparatus thereforEssential components thereof
53.
MANUFACTURING METHOD FOR NON-MAGNETIC SPATIAL RETICULATED SHELL STRUCTURE COMPOSED OF CARBON FIBER SHEETS
INNOVATION CENTER OF YANGTZE RIVER DELTA, ZHEJIANG UNIVERSITY (China)
ZHEJIANG UNIVERSITY (China)
Inventor
Luo, Yaozhi
Ge, Huibin
Cheng, Yuan
Yang, Chao
Abstract
Disclosed in the present invention is a manufacturing method for a non-magnetic spatial reticulated shell structure composed of carbon fiber sheets. A stress component of the reticulated shell structure is made of a non-magnetic carbon fiber material, connecting joints are each made of a non-magnetic titanium alloy material, a magnetic shielding layer is arranged on a roof system above a structural layer, and a non-magnetic space with magnetic field intensity lower than 1 nT is formed in a reticulated shell. The stress component is a carbon fiber sheet component, and two carbon fiber branch plates are fixed in an inter-branch connection manner to form a hollow rectangular combined section; each connecting joint is composed of a titanium alloy gusset plate, a titanium alloy bolt group and carbon fiber branch plates; and a roof system magnetic shielding layer is composed of a shielding layer pad, shielding layers, a shielding layer pressing plate, a buffer layer, a permalloy plate and a pressing strip. The present invention has the characteristics of light weight, high strength, no magnetism, and molding of an internal near-zero residual magnetic space by means of the roof magnetic shielding layer, and the like, can be applied to various functional buildings having relatively high magnetic field shielding requirements, and can also be applied to the field of common construction engineering.
Provided is a cell fast chemical reprogramming technique. By means of a provided chemical reprogramming accelerator and culture method, the time for chemical reprogramming is significantly shortened, and the reprogramming efficiency is improved by more than 10 times. The provided method can be applied to a wider range of genetic backgrounds and more types of mouse cells.
A bubble drag reduction system and a ship comprising the system. The system comprises a bottom plate (6), a top wall (7), a side wall (10), a rear wall (11), a ventilation plate (8) and a cover plate (9), wherein the bottom plate (6) is fixed to an outer plate (1) of a ship and is contoured to match an outer surface of the ship; the side wall (10) is fixed to the bottom plate (6); the top wall (7) is fixed to the top of the side wall (10), the ventilation plate (8) is detachably fixed to the middle of the side wall (10), and the cover plate (9) is detachably fixed to the bottom of the side wall (10); a rear side wall (13) is provided between the ventilation plate (8) and the top wall (7); the rear side wall (13), the ventilation plate (8), the top wall (7) and the side wall (10) jointly constitute a pressure stabilizing cavity (4); an air inlet (301) is provide in the top wall (7) of the pressure stabilizing cavity (4); the ventilation plate (8), the side wall (10) and the cover plate (9) jointly constitute an exhaust cavity (5), which has an opening in one side; the exhaust cavity (5) is in communication with the pressure stabilizing cavity (4); and the top of the opening (61) in the exhaust cavity (5) is provided with the downwards inclined rear wall (11), which extends to the rear; and a gap is provided between the rear wall (11) and the cover plate (9) and constitutes an air outlet (14). By means of the system, a low-speed uniform mesoscale bubble layer can be generated in an entire length direction of the bottom of the ship, thereby achieving a drag reduction effect.
Disclosed is a fully dynamic gain-adjustable digital microphone interface circuit powered by a low-voltage domain, comprising an audio analog front end and an analog-to-digital signal conversion circuit. The audio analog front end can improve a processing voltage domain, achieving low-voltage domain power supply processing of a high-voltage domain signal while having fully dynamic and gain-adjustable characteristics, and the power consumption level may be reduced by means of reducing the operating frequency. The analog-to-digital signal conversion circuit may achieve fully dynamic characteristics and can adapt to the characteristics of the audio analog front end, and a residual error feedback process is introduced so as to enable the conversion circuit to have noise forming characteristics and improve signal precision in a band. Furthermore, a dynamic amplifier is used in the present invention, and long-term ineffective operation of the dynamic amplifier can be avoided in a standby stage, maintaining high energy efficiency characteristics of the system. Therefore, the present invention may simultaneously exhibit the characteristics of low voltage domain power supply demand, a higher processing signal dynamic range, high-precision quantization, highly energy efficient operation, and being fully dynamic.
The present invention belongs to the field of ultra-precision machining. Disclosed is an atomic-scale deterministic machining method using a flow field driven photoelectrocatalytic cluster. The method comprises the following steps: selecting nanoparticles having a photocatalytic activity and using same as photocatalytic mediums, using a photoreduction method to realize precipitation of metal nanoparticles on the surfaces of the photocatalytic mediums, and preparing photoelectrocatalytic clusters; mixing the photoelectrocatalytic clusters with deionized water, so as to prepare a polishing solution; irradiating, by using a catalytic light source, a coupling area of a surface to be machined of a workpiece, the photoelectrocatalytic clusters and a flexible tool, and applying a bias voltage to a conductive tray of the workpiece; and applying a normal load to a flexible tool head, setting a rotating speed, and generating a hydrodynamic pressure to drive the polishing solution to flow, thereby realizing controllable removal of atomic-scale precision. In the present invention, photo-generated electrons are captured by means of metal particles in a photoelectrocatalytic cluster, thereby improving the lifetime of photo-generated carriers; and the recombination of electron hole pairs is suppressed by means of a space electric field, and a large number of new reactive active sites are formed, thereby improving the photocatalytic reaction rate in the confinement, and preventing scratching of the surface of a workpiece.
B24B 1/00 - Processes of grinding or polishingUse of auxiliary equipment in connection with such processes
B24B 49/00 - Measuring or gauging equipment for controlling the feed movement of the grinding tool or workArrangements of indicating or measuring equipment, e.g. for indicating the start of the grinding operation
58.
Fully distributed island micro-grid attack elasticity control system and method
H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
G01R 23/04 - Arrangements for measuring frequency, e.g. pulse repetition rateArrangements for measuring period of current or voltage adapted for measuring in circuits having distributed constants
G01R 31/08 - Locating faults in cables, transmission lines, or networks
H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers
59.
2 desorption system suitable for limited space in complex sailing region and flexible control method
Jiaxing Research Institute, Zhejiang University (China)
Zhejiang University (China)
Inventor
Zheng, Chenghang
Gao, Xiang
Zhou, Can
Zhang, Yongxin
Chen, Qihao
Wu, Weihong
Zhou, Zhiying
Shen, Haitao
Fan, Haidong
Li, Qingyi
Wang, Yifan
Liu, Peng
Yu, Libin
Wang, Tao
Abstract
2 rich liquid reboiling pre-desorption device to realize flexible control of operation parameters of the desorption system under different operating conditions of an engine.
B01D 53/92 - Chemical or biological purification of waste gases of engine exhaust gases
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
B01D 53/34 - Chemical or biological purification of waste gases
A system includes three modules: a local odometry module, a map feature matching module, and a map-based positioning module, where the local odometry module is configured to receive data of a camera and an inertial measurement unit (IMU); the map feature matching module is configured to detect a similarity between a scene observed by the camera at a current moment and a pre-built map scene, and obtain a feature matching pair of an image feature at the current moment and a map feature; and the map-based positioning module is configured to receive an output amount of the local odometry and the feature matching pair. In the present invention, a maintained odometry-related variable and the relative transformation between a local odometry reference system and a pre-built map reference system are expressed in a Lie group, such that a new invariant Kalman filter (IKF) algorithm is obtained.
G01C 21/00 - NavigationNavigational instruments not provided for in groups
G06T 7/246 - Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
G06V 10/44 - Local feature extraction by analysis of parts of the pattern, e.g. by detecting edges, contours, loops, corners, strokes or intersectionsConnectivity analysis, e.g. of connected components
G06V 10/74 - Image or video pattern matchingProximity measures in feature spaces
61.
Pneumatic proportional valve with high frequency response and low power consumption
A pneumatic proportional valve includes a torque motor and a pneumatic rotary valve. The torque motor includes permanent magnets, magnetically permeable yokes, an upper armature, a lower armature, an upper skeleton, a skeleton column, a lower skeleton, an exciting coil, a coil skeleton, a spring support, a spring plate and load springs. The torque motor has a single coil structure with an axis of the exciting coil coinciding with a rotation axis of the armatures, and the coil is arranged between the upper armature and the lower armature. The torque motor has the upper armature and the lower armature, and the upper armature and the lower armature have a total of four armature arms, which can form eight air gaps with an upper one and a lower one working in pair, form four pairs of magnetic circuits in parallel with each other under the excitation of a control coil.
F16K 11/06 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves
F16K 31/12 - Operating meansReleasing devices actuated by fluid
H02K 26/00 - Machines adapted to function as torque motors, i.e. to exert a torque when stalled
62.
PSEUDORABIES VIRUS (PRV) EXPRESSING PORCINE CIRCOVIRUS 2 (PCV2) CAPSID PROTEIN ON ENVELOPE AND USE THEREOF
The present disclosure provides a pseudorabies virus (PRV) expressing a porcine circovirus 2 (PCV2) capsid protein in its envelope, and use thereof. In the present disclosure, an attenuated PRV vaccine strain is used as a vector to express an exogenous immunogen. The exogenous immunogen only replaces an extracellular domain of a non-essential envelope protein of the PRV, while retaining a transmembrane domain and an intracellular domain of an original envelope protein, thereby allowing the expression of one or more exogenous immunogens on the viral envelope without changing genes of other PRV autoimmunogens. During the recombinant PRV particle being recognized by the body's immune system, the host's immune system recognizes all immunogens (exogenous immunogens and PRV autoimmunogens) on the recombinant PRV particle and then initiates an immune response, thus exerting a protective effect of a bivalent vaccine or a polyvalent vaccine based on the recombinant PRV particle.
An evolutionary compensation method for a spindle rotation error of a CNC grinding machine is provided. Feature points are determined at an edge of a central hole of a spindle of a CNC grinding machine, and a spindle rotation error in-situ measuring device is fixed on the grinding machine and aligned with the edge of the central hole; a trajectory image of the feature points is acquired by using the measuring device; a measured value of the spindle rotation error is obtained according to the trajectory image; features of the spindle rotation error are fused with the measured value of the spindle rotation error, a spindle rotation error compensation model is established, to output a spindle rotation error compensation value, thereby compensating the spindle rotation error. By continuously calibrating the error model using the measured value, accuracy of the error model has been continuously optimized.
B24B 49/12 - Measuring or gauging equipment for controlling the feed movement of the grinding tool or workArrangements of indicating or measuring equipment, e.g. for indicating the start of the grinding operation involving optical means
B24B 41/00 - Component parts of grinding machines or devices, such as frames, beds, carriages or headstocks
G05B 19/414 - Structure of the control system, e.g. common controller or multiprocessor systems, interface to servo, programmable interface controller
A portable chemiluminescence device for continuously detecting hydroxyl radicals (·OH) on-site, said device comprising a peristaltic pump (5), a mixing cell, a detection cell, a photomultiplier tube (3), a photon counter (4), a terminal (1), and an instrument housing (2). The terminal (1) is arranged outside of the instrument housing (2), and the other elements are arranged inside of the instrument housing (2). The instrument housing (2) is provided with two oxidant inlets (9) for respectively inputting two oxidants and a sample inlet (10) for inputting a sample under test. The mixing cell mixes the three and inputs same into the detection cell to generate chemiluminescence. The photomultiplier tube (3) converts an optical signal generated in the detection cell into an electrical signal, and the signal is transmitted to the terminal (1) via the photon counter (4) to display a detection result of ·OH. ·OH generated in various environmental media such as air, water, and soil may be measured, thereby determining the generation behavior of ·OH.
A three-dimensional (3D) anti-counterfeiting code label (100) and an identification method therefor. The 3D anti-counterfeiting code label (100) comprises a label main body (1) and heterogeneous bodies (2), wherein the heterogeneous bodies (2) are randomly distributed on the label main body (1). An identification method for a 3D anti-counterfeiting code label comprises the steps of: S1, collecting the positions of heterogeneous bodies (2) by means of at least two focal planes of different heights by using an image collection device, so as to obtain depth parameters and horizontal two-dimensional coordinate parameters of the heterogeneous bodies (2); and S2, obtaining a 3D image feature of a 3D anti-counterfeiting code label (100) according to the depth parameters and the horizontal two-dimensional coordinate parameters of the heterogeneous bodies (2), and according to a database recording the 3D image feature, making a comparison and reading label information fed back by the 3D anti-counterfeiting code label (100).
Provided is a light backdoor attack method for a physical world. The method includes: generating, by a flashlight, a light trigger on a traffic sign; capturing and acquiring, by a camera, a backdoor training set, and marking all images in the backdoor training set as a target label; constructing a training set according to the backdoor training set and a clean training set; training a backdoor model using the training set to obtain a trained backdoor model; and evaluating effectiveness of light backdoor attack by applying the trained backdoor model to a testing set. The method can poison DNNs to achieve a more covert backdoor attack and provide a new idea for physical backdoor attack field.
G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
68.
QUICK LIST DECODING METHOD FOR POLARIZATION-ADJUSTED CONVOLUTIONAL CODE SPECIAL NODES
Provided are a quick list decoding method and apparatus for polarization-adjusted convolutional code special nodes, a computer electronic device, a computer-readable storage medium, a computer program product, and a computer program. The method comprises: determining special nodes in a decoding tree for list decoding of a polarization-adjusted convolutional code, wherein the special nodes comprise a source node and a code rate-0 or repetition code sub-node sequence, and the special nodes are identified by means of a sequence set; calculating a log-likelihood ratio of the source node corresponding to the special node, and determining the number of paths; on the basis of the log-likelihood ratio and the sequence set corresponding to the special nodes, calculating the metrics of the paths, and reserving the paths having the minimum metric, the number of reserved paths being the set number of lists; decoding the source node by taking the reserved paths as inputs to obtain an estimated code word of each path of the source node; and calculating an estimated output bit and an estimated information bit of the special node by means of the estimated code word.
H03M 13/29 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes combining two or more codes or code structures, e.g. product codes, generalised product codes, concatenated codes, inner and outer codes
69.
METHOD FOR PREDICTING THERMAL ERROR OF SPINDLE OF COMPUTER NUMERICAL CONTROL MACHINE TOOL ON BASIS OF TWIN FEATURE TRANSFER BETWEEN VIRTUAL SAMPLE MACHINE TOOL AND PHYSICAL SAMPLE MACHINE TOOL
A method for predicting a thermal error of a spindle of a computer numerical control machine tool on the basis of twin feature transfer between a virtual sample machine tool and a physical sample machine tool. The method comprises: firstly, building a physical sample machine experiment table for a spindle, and performing screening by using a thermal hysteresis clustering algorithm, so as to obtain temperature-sensitive points outside a spindle of a physical sample machine tool, thereby establishing an auto-regressive distribution hysteresis model for thermal errors; secondly, according to a thermal hysteresis effect, determining, on the spindle of the physical sample machine tool, temperature co-stagnation points of the temperature-sensitive points outside the spindle of the physical sample machine tool, so as to construct a thermal error analysis model for the spindle of the physical sample machine tool; and then establishing a virtual sample machine tool of a machine tool, migrating twin features of the physical sample machine tool, and integrating a twin coupling relationship between the spindle of the physical sample machine tool and a spindle of the virtual sample machine tool, so as to predict a thermal error of a spindle of a computer numerical control machine tool on the basis of twin feature transfer between the virtual sample machine tool and the physical sample machine tool. When it is difficult to provide a sensor on a spindle of a computer numerical control machine tool, the accuracy of the prediction of a thermal error of the spindle can be improved.
G05B 19/408 - Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by data handling or data format, e.g. reading, buffering or conversion of data
70.
EVOLUTIONARY COMPENSATION METHOD BASED ON IN-SITU TIMING MEASUREMENT AND FOR SPINDLE ROTATION ERRORS OF COMPUTER NUMERICAL CONTROL GRINDING MACHINE
Disclosed in the present invention is an evolutionary compensation method based on in-situ timing measurement and for spindle rotation errors of a computer numerical control grinding machine. The method comprises: first, determining a plurality of feature points at an edge of a central hole of a spindle of a computer numerical control grinding machine, fixing to the grinding machine an in-situ measurement apparatus for spindle rotation errors of the computer numerical control grinding machine, and aligning the apparatus with the edge of the central hole; next, collecting trajectory images of the feature points in the edge of the central hole of the spindle by using the measurement apparatus; then, according to the trajectory images, performing calculation to obtain measured spindle rotation error values; fusing spindle rotation error features of the computer numerical control grinding machine with the measured spindle rotation error values, establishing a spindle rotation error compensation model, and the compensation model outputting spindle rotation error compensation values, and compensating for spindle rotation errors according to the spindle rotation error compensation values; and during compensation, calibrating the error compensation model by using the measured spindle rotation error values, so as to continuously optimize and compensate for the spindle rotation errors. By means of the present invention, the accuracy of compensation for spindle rotation errors of a computer numerical control grinding machine is improved during the actual machining process of the computer numerical control grinding machine.
B23Q 17/24 - Arrangements for indicating or measuring on machine tools using optics
G01B 11/00 - Measuring arrangements characterised by the use of optical techniques
B24B 49/12 - Measuring or gauging equipment for controlling the feed movement of the grinding tool or workArrangements of indicating or measuring equipment, e.g. for indicating the start of the grinding operation involving optical means
71.
METHOD AND SYSTEM FOR AUTOMATICALLY DETECTING NITROGEN CONTENT, ELECTRONIC DEVICE AND MEDIUM
A method and a system for automatically detecting nitrogen content, an electronic device and a medium are provided and relate to the field of nitrogen content detection. The method includes: selecting an optimal nitrogen content prediction model from a prediction model base according to a variety and a growth stage of a target crop to obtain a target model; detecting, based on a spectral image of the target crop, a nitrogen content of the target crop by using the target model to obtain a predicted value of the nitrogen content. The optimal nitrogen content prediction model is the model with best performance among a first nitrogen content prediction model constructed based on a hyperspectral vegetation index, a second nitrogen content prediction model constructed based on a sensitive band, and a third nitrogen content prediction model constructed based on a machine learning method.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/84 - Systems specially adapted for particular applications
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G06V 10/58 - Extraction of image or video features relating to hyperspectral data
G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
Disclosed are a VCD vector compression method and device based on circuit toggle behaviors. The method comprises: converting a VCD format file into a current matrix model, wherein three dimensions of the current matrix model are one time dimension and two spatial dimensions; performing preliminary screening based on an overall toggle feature: dividing the current matrix into several time segments in accordance with an equal interval in the time dimension, and performing screening according to the overall toggle feature, and forming a preliminary screened current distribution matrix by the screened time segments; performing fine screening based on region toggle features: performing further screening according to local toggle features, and forming a fine screened current distribution matrix by the screened time segments; and re-outputting the fine screened current distribution matrix as a VCD format file after vector compression.
Disclosed in the present invention is a confidence-aware service pattern optimization method, wherein the service pattern optimization method comprises the following steps: (1) inputting an original pattern Pa to be optimized; (2) initializing a candidate list PaList of the original pattern Pa; (3) initializing a temperature T; (4) initializing confidence C; (5) initializing a maximum number of iterations IterMax; (6) initializing a termination threshold Th; (7) circularly searching a target pattern Pa* according to pattern optimization indexes, wherein the number of circulations is IterMax; (8) reducing the temperature T; (9) if the pattern Pa* obtained at the end of the cycle in step (7) remains consistent for consecutive Th times, obtaining the Pa* as an optimized target pattern; otherwise, jumping to step (7). By introducing the confidence mechanism, the search speed and search step size can be dynamically adjusted in the search space with different optimization potentials, which greatly saves the optimization time and improves the optimization effect.
A batch private information retrieval method and apparatus, including: agreeing on a hash function, calculating a serial number index in an original database, retaining a result of each serial number index for each hash function, and obtaining a first hash bucket; filling an index of a batch query into a second hash bucket of a same length as the first hash bucket by the client, and encoding a filling result by using a constant weight code encoding manner; encrypting an obtained encoding result as a batch query request by the client; comparing the batch query request with the first hash bucket by the server to obtain a corresponding intermediate result, calculating correspondingly the intermediate result and the original database to obtain a corresponding query result ciphertext; and decrypting the query result ciphertext by the client, and thus simultaneously obtaining a query result of the batch query request.
Disclosed in the present invention are a batch privacy information retrieval method and device. The method comprises: a client and a server agreeing on hash functions, performing calculation on serial number indexes in an original database by means of cuckoo hash technology, keeping a result of each serial number index for each hash function, and obtaining a first hash bucket containing a plurality of baskets; the client filling a second hash bucket having the same length as the first hash bucket with a batch query index by means of a cuckoo hash algorithm, and encoding a filling result in a constant weight code encoding mode; the client encrypting an obtained encoding result by using homomorphic encryption technology to serve as a batch query request; the server comparing the batch query request with the first hash bucket by using the homomorphic encryption technology to obtain a corresponding intermediate result, and performing corresponding calculation on the intermediate result and the original database to obtain a corresponding query result ciphertext; and the client decrypting the query result ciphertext so as to obtain query results of the batch query request.
A modification method and a tool for quickly retrofitting electronic hardware on an orthosis. The method mainly comprises drilling holes in an existing orthosis and embedding a magnetic connector or a conductive fabric electrode, ironing a circuit on the stereoscopic surface of the orthosis, and fixing a magnetic electronic functional module on the orthosis through magnetic attraction with the magnetic connector to realize circuit communication. The method is realized by a tool kit, which comprises a drilling tool, a circuit ironing tool, a magnetic connector, a magnetic electronic functional module, a wire tape and a conductive fabric electrode. This method can flexibly and quickly transform the orthosis according to the needs, with a strong applicability, and does not require the user to have circuitry expertise, which can shorten the customization and development cycle of the smart orthoses.
A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
H01R 13/62 - Means for facilitating engagement or disengagement of coupling parts or for holding them in engagement
77.
BACTERIAL CELLULOSE-PRODUCING KOMAGATAEIBACTER EUROPAEUS STRAIN FMES AND USE THEREOF
Innovation Center of Yangtze River Delta, ZJU (China)
Zhejiang University (China)
Inventor
Chen, Qihe
Liu, Siyu
Shi, Ying
Qi, Qianhui
Abstract
Provided is a bacterial cellulose-producing Komagataeibacter europaeus strain FMES and use thereof. The strain FMES is deposited in the China Center for Type Culture Collection (CCTCC) with a deposit number of CCTCC NO: M20221627. The strain FMES is isolated from traditional vinegar brewing and can efficiently produce bacterial cellulose through static culture. The strain FMES can also be used to produce a novel, green, and non-toxic degradable biotextile. Therefore, the strain FMES is expected to replace leather, textiles, and films derived from animals, plants, and petrochemicals, and shows a potential to serve as a sustainable alternative of the textiles.
An orthogonal reaction controlled phase-separated aggregate, a method for preparing same, and a use. A nucleic acid-protein combination which can form a phase-separated aggregate comprises: a modified protein and modified nucleic acids, wherein the nucleic acids comprise DNA and RNA, and the modified protein and the modified nucleic acids can undergo a click-to-release reaction, so that phase separation occurs to the protein and the nucleic acids to form the phase-separated aggregate. The nucleic acid-protein combination realizes the controllable preparation of the aggregate and the long-term retention of active ingredients. The nucleic acid-protein combination comprises two separated components extracellularly, and a phase-separated aggregate can be formed intracellularly by means of a click chemistry reaction, so that the anti-tumor effect of a drug is improved, and the survival time of a mouse having a tumor is prolonged.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 47/56 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
The present invention relates to the field of biomedicine. Disclosed is the use of L-theanine in the preparation of an angiogenesis-promoting agent. Provided in the present invention is the use of L-theanine in the preparation of an angiogenesis-promoting agent. In the present invention, experiments found for the first time that L-theanine can promote post-ischemic angiogenesis, and is expected to provide a new theoretical basis and potential intervention targets for the treatment of post-ischemic angiogenesis.
A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
80.
RESOLUTION-BASED DECODING AND ENCODING METHODS AND BITSTREAM
GUANGDONG OPPO MOBILE TELECOMMUNICATIONS CORP., LTD. (China)
Inventor
Yu, Lu
Jin, Xiake
Wang, Chuchu
Li, Sicheng
Dai, Zhenyu
Abstract
Embodiments of the disclosure provide resolution-based decoding and encoding methods and a bitstream. The method includes the following. A bitstream is parsed to obtain a current patch. Whether the current patch is a patch whose resolution is to be changed is determined. When the current patch is a patch whose resolution is to be changed, the bitstream is parsed to obtain a scaling-rate parameter of the current patch. A scaling factor for the current patch is determined based on the scaling-rate parameter of the current patch. Coordinates of the current patch in a three-dimension (3D) space coordinate system are obtained based on the scaling factor for the current patch.
H04N 19/30 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using hierarchical techniques, e.g. scalability
H04N 19/17 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using adaptive coding characterised by the coding unit, i.e. the structural portion or semantic portion of the video signal being the object or the subject of the adaptive coding the unit being an image region, e.g. an object
H04N 19/46 - Embedding additional information in the video signal during the compression process
81.
METHOD AND SYSTEM FOR DETECTING STRUCTURAL DAMAGE BASED ON NExT-RECURRENCE PLOTS
A method and system for detecting structural damage based on NExT-recurrence plots is provided. The method includes: acquiring a time-history signal of an acceleration response at each measured point of a structure under different damage conditions; processing the time-history signal of the acceleration response by using a NExT method to obtain cross-correlation function signals of acceleration responses at different measured structure points; performing recurrence plot processing on the cross-correlation function signals, and stacking generated recurrence plots to obtain three-dimensional recurrence plots; dividing the three-dimensional recurrence plots into a training set and a validation set; training and validating a convolutional neural network model through the training set and the validation set, respectively; detecting structural damage through a trained convolutional neural network model. Damage to the structure can be effectively detected and the accuracy and robustness of the detection can be improved to a maximum extent.
Provided are an sgRNA targeting a porcine pLEG1abc locus, and a recombinant expression vector comprising the sgRNA, and a preparation method therefor and the use thereof. On the basis of the recombinant expression vector, also provided are a porcine fetal fibroblast in which the porcine pLEG1abc locus is deleted, and a preparation method therefor. The three genes, i.e. pLEG1a, pLEG1b and pLEG1c, on the same chromosome of a pig can be effectively and accurately deleted at the same time, so as to obtain a porcine fetal fibroblast in which a liver-enriched gene 1 is deleted, thereby providing a technical basis for subsequent construction of an experimental porcine model with pLEG1 deletion. In addition, on the basis of a CRISPR/Cas9 system, an sgRNA targeting a long-fragment gene of at least 80,000 bp is designed according to the sgRNA target site, and the long-fragment gene is successfully deleted, so that the efficient deletion of a long-fragment gene on the basis of a CRISPR/Cas9 system is realized.
Disclosed in the present invention are a method for optimizing flip angles in a magnetic resonance variable flip angle sequence, a CEST imaging method, a medium, and a device. According to the present invention, a signal-to-noise ratio (SNR) enhancement problem is modeled as a flip angle optimization problem, and a total objective function composed of an SNR maximization objective term and a resolution penalty term is constructed, wherein the total objective function can be solved for an optimal solution by finding derivatives with respect to flip angles, so as to obtain an optimal flip angle capable of maximizing SNR. In the present invention, the objective function comprises the resolution penalty term, so that resolution can also considered in variable flip angle CEST when the SNR is optimized. Compared with a conventional filtering method, the present invention avoids noise amplification caused by filtering, and does not require manual presetting of a window function.
The present invention relates to the technical field of magnetic resonance. Disclosed are a CEST lipid artifact elimination method, a medium, a device, and a magnetic resonance imaging apparatus. According to the present invention, a lipid multi-peak model is incorporated into a simplified water-magnetization transfer (MT) two-pool Bloch-McConnell equation model for iterative solving, and fitting is performed on water, MT, and lipid multi-peak signals to obtain a reference signal for a CEST effect without direct lipid artifacts, and finally, the indirect influence of a lipid signal on a CEST signal is eliminated by means of normalization. A Bloch-McConnell equation involving lipids used in the present invention can more truly reflect the composition of a collected signal, so as to obtain a more accurate CEST reference signal. The present invention can eliminate lipid artifacts in CEST signals without adjusting the collection sequence, thereby improving the accuracy of CEST imaging.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
G01R 33/565 - Correction of image distortions, e.g. due to magnetic field inhomogeneities
85.
FAULT DIAGNOSIS METHOD AND APPARATUS FOR FOUR-SWITCH BUCK-BOOST CONVERTER
Disclosed is a fault diagnosis method for a four-switch Buck-Boost converter, including the following steps: obtaining circuit parameters when different faults occur, labeling fault parameters with fault types, and combining the fault parameters and labels into a data set; constructing a simplified self-organizing neural network consisting of a plurality of nonlinear operation modules, a weighting module, and an analysis module; performing training by using the data set to obtain a self-organizing neural network for determining the faults of the converter; and inputting the circuit parameters of the four-switch Buck-Boost converter to the self-organizing neural network, so as to determine the fault types of the four-switch Buck-Boost converter. Further disclosed is a fault diagnosis apparatus for a four-switch Buck-Boost converter. The method provided by the present invention is capable of simultaneously identifying and locating the faults of the four-switch Buck-Boost converter, such as an open circuit fault of a switching tube, aging of a capacitor, and aging of an inductor, and has good diagnosis accuracy and generalization capability.
A method and a system for large-scale traffic generation based on programmable network technology, which are used for the research on network operation and maintenance and defense of attacks such as DDOS. According to the method, the required large-scale traffic is generated as required through the coordination of servers and programmable switches. The method specifically comprises the steps of designing a series of primitives which are based on intentions and are irrelevant to underlying architecture details, and reducing the description difficulty of generating large-scale traffic intentions; completing required configurations on the switch and the server by the designed cooperation mechanism of the server and programmable switch according to intentions expressed by different types of primitives, and achieving large-scale traffic generation by coordinating and utilizing server and switch resources.
H04L 69/326 - Intralayer communication protocols among peer entities or protocol data unit [PDU] definitions in the transport layer [OSI layer 4]
87.
WATER-SOLUBLE DIETARY FIBER, USE THEREOF IN PREPARATION OF MEDICAMENT THAT PROMOTES METABOLISM OF ELLAGIC ACID INTO UROLITHIN A, AND PHARMACEUTICAL COMPOSITION
The present disclosure provides a water-soluble dietary fiber (WSDF), use thereof in preparation of a medicament that promotes metabolism of ellagic acid (EA) into urolithin A, and a pharmaceutical composition, and belongs to the technical field of biological pharmaceuticals. The WSDF provided by the present disclosure includes at least two components selected from the group consisting of gellan gum, guar gum, carrageenan, fructooligosaccharide, xylooligosaccharide, malto-oligosaccharide, pectin, β-glucan, polydextrose, sodium alginate, gum arabic, resistant dextrin, xanthan gum, tragacanth gum, and inulin. In the present disclosure, compounding the foregoing different combinations of the WSDF and EA to feed mice may significantly increase the average urolithin A content in mouse feces. Visibly, the WSDF alone or in combination with EA may improve metabotypes of the EA in the body and increase urolithin A content, providing a new means for treating diabetes, obesity, senescence and central nervous system lesions.
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
USE OF INTESTINAL PROBIOTIC IN PREPARATION OF MEDICAMENT THAT PROMOTES METABOLISM OF ELLAGIC ACID INTO UROLITHIN A, PHARMACEUTICAL COMPOSITION AND USE THEREOF
The present disclosure provides use of an intestinal probiotic in preparation of a medicament that promotes metabolism of ellagic acid (EA) into urolithin A, a pharmaceutical composition and use thereof, and belongs to the technical field of biomedicine. In the present disclosure, probiotics capable of changing metabotypes of EA are selected from a plurality of probiotics. These probiotics alone or in combination can change an intestinal flora structure of a metabotype B and/or 0 population, thereby improving the efficiency of the metabolism of EA into urolithin A and increasing a yield of urolithin A. The present disclosure provides an intestinal probiotic for involving in and promoting the metabolism of EA into urolithin A, and provides a new idea for the treatment of diabetes, obesity, senescence, and diseases caused by central nervous system lesions and viral infection using urolithin A as an active pharmaceutical ingredient.
The present invention discloses a human mobility prediction method based on a generative adversarial network. According to the method, the integration of spatio-temporal features of multimodal data is studied by virtue of studying urban human mobility prediction during the pandemic. A human mobility mode is difficult to be predicted during the pandemic due to complex multimodal data such as complicated social background, policy and pandemic situation. The analysis of human mobility data from three cities in China shows that different cities have highly similar human mobility modes during the pandemic, despite of great differences between them. On this basis, the disclosure designs a prediction model, in which the effects of the multimodal data on the spatio-temporal features of the human mobility are modeled integrally. In addition to this, the model can help the government evaluate the potential effects of different policies on human mobility better, and optimize policy development.
G16H 50/80 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for detecting, monitoring or modelling epidemics or pandemics, e.g. flu
90.
Detection Method and Device Based on Quantum Induced Coherence
A detection method and device based on quantum induced coherence do not directly measure the signal from the object, but transmit the object information from the first probe light to the locally kept first reference light through quantum coherence. The distance and the image information of the object can be obtained simultaneously from the interference between the first and the second reference light. This non-contact detection method can effectively avoid the background noise induced low signal-to-noise ratio (SNR) in traditional optical remote sensing and quantum illumination radar, and keep it working under saturated attack. Further, the method can simultaneously detect the distance and image information of the object without the joint measurement of two entangled subsystems, and the response wavelength of the detector is different from that of the light wavelength interacting with the object, which greatly reduces the requirement on the detector.
22 contrast difference between different acceleration factor image frames, so that reconstructed images have consistency. The method, as an automatic trajectory design solution, is particularly suitable for three-dimensional multi-frame magnetic resonance imaging.
G01R 33/56 - Image enhancement or correction, e.g. subtraction or averaging techniques
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
92.
USE OF GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE GENE ASSOCIATED WITH OIL AND PROTEIN QUALITY OF GOSSYPIUM HIRSUTUM
Disclosed is the use of a glucose-methanol-choline oxidoreductase gene associated with the oil and protein quality of Gossypium hirsutum. Provided are the cDNA sequence SEQ ID NO. 1 and the genome sequence SEQ ID NO. 2 of the gene in the tetraploid Gossypium hirsutum. The provided gene is obtained by means of the re-sequencing of a Gossypium hirsutum variety and a genome-wide association study, and is significantly associated with the oil and protein content of cottonseed kernels. The SNP genotype of the gene is used for distinguishing high-quality and low-quality haplotypes. The variety populations are classified according to the two haplotypes, and statistical analysis is performed on the basis of quality traits, which also prove that GhGMC has a significant correlation with the oil and protein content of cottonseed kernels. The above-mentioned results show that the gene has important research value and application prospects in efficiently identifying high-oil and high-protein cotton varieties, improving the oil and protein content of cotton, and cultivating a new high-oil and high-protein cotton variety.
C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
93.
METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATING OR ALLEVIATING GLIOMAS IN A SUBJECT
A method for treating or alleviating gliomas in a subject is provided, including inhibiting olfactory inputs in the subject. A pharmaceutical composition applicable for treating or alleviating gliomas in a subject is further provided, including at least one inhibitor of an olfactory neuronal circuit in a brain of the subject.
A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A61K 31/7072 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
A neural model storage system and method for an operating system of a brain-inspired computer are provided. The method includes: storing a neural model on three computing nodes, selecting the computing nodes by dynamically calculating a weight according to the number of idle cores of the first computing node, the number of failures of the first computing node, and failure time of the first computing node in each failure thereof, reading the neural model in the same computing node or cross-computing node, recovering from failures of non-master nodes, recovering from failures of the master node, and recovering from a whole machine restart or failure.
This invention pertains to compounds of the general formula (I) and their applications. The invention introduces a novel class of compounds exhibiting androgen receptor (AR) antagonistic activity. In particular, these compounds target a binding pocket located in the dimer interface of AR ligand binding domain (AR-LBD). These compounds effectively disrupt AR dimerization, thereby suppressing AR signaling. The high AR antagonistic activity and favorable safety profile of the compounds provided by the present invention have been substantiated through biochemical assays and animal models. Therefore, these compounds can be utilized in the formulation of medications to treat diseases characterized by abnormal expression of AR, including but not limited to prostate cancer, metastatic prostate cancer, castration-resistant prostate cancer, breast cancer and ovarian cancer.
C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
C07D 417/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
96.
COOPERATIVE POSITIONING SYSTEM AND METHOD FOR UNMANNED UNDERWATER VEHICLE (UUV) CLUSTER BASED ON RANGING AND INFORMATION INTERACTION
Some embodiments of the disclosure provide a cooperative positioning system and method for an unmanned underwater vehicle (UUV) cluster based on ranging and information interaction. In some examples, the cooperative positioning system includes one master UUV, multiple slave UUVs, and a cooperative positioning apparatus. In some examples, the cooperative positioning method includes following steps. A master UUV and a slave UUV perform internal clock disciplining. The master UUV periodically packages a location of the master UUV and a covariance matrix of location estimation into a cooperative positioning data packet and broadcasts the cooperative positioning data packet to slave UUVs of a cluster. The slave UUV receives the cooperative positioning data packet. A cooperative positioning apparatus of the salve UUV constructs a state and a measurement equation according to data. The cooperative positioning apparatus calculates and obtains a cooperative positioning result by using an extended Kalman filter (EKF).
B63G 8/39 - Arrangements of sonic watch equipment, e.g. low-frequency, sonar
G01S 5/18 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations using ultrasonic, sonic, or infrasonic waves
G01S 19/49 - Determining position by combining or switching between position solutions derived from the satellite radio beacon positioning system and position solutions derived from a further system whereby the further system is an inertial position system, e.g. loosely-coupled
97.
SELF-EXCITATION TEST METHOD FOR REINFORCEMENT QUALITY OF VIBROFLOTATION GRAVEL PILE COMPOSITE FOUNDATION
A self-excitation test method for reinforcement quality of vibroflotation gravel pile composite foundations, comprising: performing elastic wave velocity tests and test pile testing wave velocity partition on a pretreated foundation, and performing excess pore-water pressure monitoring so as to obtain an excess pore-water pressure; selecting detectors and a collector so as to establish a gravel pile construction excitation signal acquisition system, and arranging a spatial array of the detectors; collecting in real time an elastic wave signal to perform filtering processing and signal recognition, extracting the arrival time of the elastic wave signal, and constructing a travel-time equation set and performing iterative inversion on the elastic wave velocities of the wave velocity partition; establishing a corresponding relationship between an effective confining pressure and relative compactness of a soil body and the elastic wave velocities, so as to calculate the relative compactness of the soil body; and comparing to judge the reinforcement quality. By means of the wave velocity inversion and analysis mode, the present invention performs iterative processing on a travel-time equation set to invert elastic wave velocities and further perform wave velocity interpretation so as to determine the relative compactness of a soil body, thereby achieving real-time testing of the reinforcement quality of gravel pile composite foundations.
E02D 1/00 - Investigation of foundation soil in situ
E02D 3/08 - Improving by compacting by inserting stones or lost bodies, e.g. compaction piles
E02D 3/054 - Improving by compacting by tamping or vibrating, e.g. with auxiliary watering of the soil involving penetration of the soil, e.g. vibroflotation
G01N 29/07 - Analysing solids by measuring propagation velocity or propagation time of acoustic waves
G01N 9/24 - Investigating density or specific gravity of materialsAnalysing materials by determining density or specific gravity by observing the transmission of wave or particle radiation through the material
G01N 9/36 - Analysing materials by measuring the density or specific gravity, e.g. determining quantity of moisture
G01D 21/02 - Measuring two or more variables by means not covered by a single other subclass
98.
ACTIVE PRESSURE COMPENSATOR FOR DEEP-SEA SAMPLING AND PRESSURE COMPENSATION METHOD THEREOF
An active pressure compensator for deep-sea sampling includes a spring chamber, a cam piston pump, and a circuit chamber; the spring chamber is configured to provide compensation liquid for the cam piston pump; the cam piston pump is configured to be able to draw liquid from the spring chamber and pump liquid to the circuit chamber; the circuit chamber is configured to be connected to a mechanism to be pressurized, and is provided therein with a pressure sensor and a control circuit board, the pressure sensor is configured to detect pressures of the compensation liquid from cam piston pump and the mechanism to be pressurized, the control circuit board is configured to control working of the cam piston pump based on pressure data feedback from the pressure sensor and thereby realize active pressure compensation for the mechanism to be pressurized. A pressure compensation method using the compensator is further provided.
F04B 17/03 - Pumps characterised by combination with, or adaptation to, specific driving engines or motors driven by electric motors
F04B 49/22 - Control of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for in, or of interest apart from, groups by means of valves
G01N 1/14 - Suction devices, e.g. pumpsEjector devices
G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
99.
A TELE-HEALTH SYSTEM OF REHABILITATION TRAINING GUIDANCE FOR PATIENTS WITH CHRONIC RESPIRATORY FAILURE
The present invention discloses a tele-health system of rehabilitation training guidance for patients with chronic respiratory failure, comprising a functional assessment and rehabilitation training equipment group, a patient mobile terminal, a cloud server, and a doctor mobile terminal; the functional assessment and rehabilitation training equipment group interacts with the patient mobile terminal, and the patient mobile terminal and the doctor mobile terminal communicate with the cloud server, respectively. The system of the present invention can grade the acquired respiratory muscle test evaluation results, limb muscle strength test evaluation results and sputum excretion ability test evaluation results, generate the recommended rehabilitation prescription corresponding to the grade, and numerically describe the exercise intensity; the system can achieve individualized customization of the recommended rehabilitation prescription, and achieve precise control of volume of exercise and place the patient in a beneficial range of volume of exercise.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 5/22 - ErgometryMeasuring muscular strength or the force of a muscular blow
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
100.
Composite Oxide Containing Tungstate Nanoclusters, And Preparation Method And Application Thereof
The invention belongs to the field of catalysts, and particularly relates to a composite oxide containing tungstate nanoclusters, and a preparation method and application thereof. The tungstate nanocluster-containing composite oxide comprises an alkali metal element A, a tungsten element W, an auxiliary agent element M, and an oxygen element O, wherein the alkali metal element A, the tungsten element W and the auxiliary agent element M form a composite with the oxygen element O. The composite oxide as a cocatalyst can obviously improve the selectivity and the yield of C2 in the oxidative coupling of methane reaction with co-fed methane and oxygen.
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