Disclosed is a finite element modeling system and method for hydraulic fracturing problems based on a large language model. The method is implemented by the system. The method comprises: a user inputting a key description of a finite element model desired to be generated; a large language model of a cloud service platform generating a key parameter file; a mesh tool generating a mesh file; a parameter mesh coupling tool generating a finite element model file; a computing server executing the finite element model file, a system output unit prompting the user of completion of modeling and execution, and a display interface displaying a visualized finite element model and an execution result; the user determining whether an expectation is satisfied; if the expectation is not satisfied, the user re-inputting the description; if the expectation is satisfied, the user outputting the finite element model and the execution result.
A preparation method for a lithium metal powder, a product thereof, a prepared lithium metal negative electrode, and a finally assembled liquid electrolyte lithium-ion battery and solid electrolyte lithium-ion battery. The preparation method for a lithium metal powder comprises: mixing a lithium metal raw material with a polymer additive in an inert gas atmosphere, and then subjecting the mixture to freezing ball milling. The polymer additive does not react with the lithium metal raw material, and the Rockwell hardness of the polymer additive is 70-110. By means of the preparation method, a lithium metal powder having a uniform size can be prepared, the median particle size of which is not higher than 500 nm and minimally can reach 10 nm; and the preparation method has a low raw material cost and a simple and feasible process. A lithium-ion battery assembled by taking the lithium metal powder prepared by means of the method as a negative electrode active component has a high dendritic crystal growth critical current density and excellent electroplating/stripping cycle stability.
The present invention discloses a wide voltage window aqueous electrolyte solution for forming an SEI film based on a physical process, including: an additive, an electrolyte and water, where the additive is a long-chain compound having both opposite charge functional groups and having opposite wettability; and the electrolyte is a soluble inorganic salt of an alkali metal. The present invention further provides a method for preparing the aqueous electrolyte solution described above and use of the aqueous electrolyte solution in an electrochemical energy storage device, and the electrochemical energy storage device includes a button supercapacitor, a button ionic capacitor or a pouch supercapacitor. According to the present invention, fan SEI layer is formed at an interface through a pure physical electrostatic adsorption process, a free water content at the interface is precisely reduced to inhibit water decomposition, thus maintaining relatively high ionic conductivity while widening a voltage window, effectively overcoming the problems of low conductivity of a traditional high-voltage aqueous electrolyte solution and consumption of the electrolyte solution for forming an SEI film based on a chemical process, and realizing the high capacity, long cycle life and excellent rate performance in aqueous energy storage devices.
Disclosed is a variable-A-value free bending forming device capable of processing pipe fittings of different outer diameters. The device comprises a bending forming module, clamping and fixing modules, and a spherical bearing. The bending forming module is used for clamping a bent section of a pipe blank. Multiple clamping and fixing modules on a rear side of the bending forming module are evenly distributed along the circumference of the pipe blank, and are used for clamping and limiting an unbent section of the pipe blank during a bending forming process. Clamping mechanisms of the bending forming module and the clamping and fixing module have overall radial movement freedom and circumferential movement freedom for clamping jaws, and can meet the requirements for clamping pipe fittings of different outer diameters. Each clamping and fixing module adjusts the A-value during forming by adjusting the positions of an arc-shaped limiting block and a clamping support base. The present invention enables efficient single-die, multi-pipe processing in a free bending forming device for pipe fittings, reducing the time and cost required for die changes. The variable A value expands the application range of the device and further improves the forming quality of three-dimensional bent pipes.
The present invention relates to a light regulation and control screen, its system and method thereof. The light regulation and control screen includes a first conductive structure, a second conductive structure, a light response structure disposed between the first and the second conductive structure, and a bistable display structure disposed between the first and the second conductive structure and located on one side of or inside the light response structure. The method has low power consumption and extremely fast response rate, by using the electrical property of the light response structure for color rendering and erasing. Only the area irradiated by light can be in a conductive state to realize a selective erasing, while other areas of the light response structure are still insulated. The present invention does not need complex circuit designs and additional sensing structures, and it is convenient for manufacturing large-size screens and promoting wide applications.
G02F 1/139 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells characterised by the electro-optical or magneto-optical effect, e.g. field-induced phase transition, orientation effect, guest-host interaction or dynamic scattering based on orientation effects in which the liquid crystal remains transparent
G02F 1/167 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on translational movement of particles in a fluid under the influence of an applied field characterised by the electro-optical or magneto-optical effect by electrophoresis
G02F 1/1685 - Operation of cellsCircuit arrangements affecting the entire cell
6.
MELASTOMA DODECANDRUM PROANTHOCYANIDIN ANALOG AND EXTRACTION METHOD THEREOF
Ningbo Innovation Center, Zhejiang University (China)
Inventor
Chen, Wei
Xu, Yang
Xie, Lianghua
Hou, Dongyuan
Abstract
Provided are a Melastoma dodecandrum proanthocyanidin analog and an extraction method thereof. In the method, Melastoma dodecandrum fruit is subjected to alcohol extraction to obtain a crude extract of Melastoma dodecandrum Lour. The crude extract of the Melastoma dodecandrum Lour. is subjected to extraction with ethyl acetate to obtain a Melastoma dodecandrum extract, and the Melastoma dodecandrum extract is subjected to preparative liquid chromatography purification to obtain the Melastoma dodecandrum proanthocyanidin analog.
A method and a system for methanol synthesis via plasma-oxygen carrier-catalysis coupling provided. CO2 is activated and decomposed using an enhanced vibrational-state atmospheric-pressure plasma jet, while H2O is dissociated by utilizing the heat generated in the plasma environment. An integrated oxygen carrier captures the O2 produced from the decomposition of CO2 and H2O, facilitating forward reactions and enabling the in-situ capture of O2 from the gas products. This process yields oxygen-free syngas (CO and H2), which is then efficiently and selectively converted into methanol over a Ni—Ga catalyst at atmospheric pressure. This configuration achieves an orderly conversion of carbon and hydrogen from CO2 and H2O into liquid methanol under atmosphere pressure, characterized by high reactant conversion and energy efficiency. Additionally, this method and system support the use of intermittent and distributed renewable energy sources due to their fast on-off capability, high reaction rate, and simple design features.
C07C 1/04 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon from oxides of carbon from carbon monoxide with hydrogen
A resource allocation method for allocating resources to respective applications based on user request information in a microservice system, which includes: acquiring a target optimization model that includes a plurality of sub-optimization models in one-to-one correspondence to resources; an optimization goal of each of the plurality of sub-optimization models being to minimize a sum of average response time of all of applications on a corresponding resource; variables of the sub-optimization model including a decision variable and an environmental variable; acquiring environmental parameters currently corresponding to the microservice system; and solving respective sub-optimization models in parallel based on the environmental parameters according to ADMM to obtain optimal solutions corresponding to respective decision variables and generate a corresponding resource allocation strategy. By solving the respective sub-optimization models in parallel, an optimal allocation result corresponding to respective resources can be obtained and the average response time of the respective applications are optimized.
Provided is a method for predicting vibration response and stiffness degradation of a helical gear. The method includes: establishing a lumped parameter dynamic model of a gear system according to a meshing condition of a pair of gears, considering that the gear system is a multi-degree-of-freedom system under the action of a deterministic force and a random force, establishing a digital twin model of the system at multiple time scales of characteristic time and running time, calculating a translation-vibration coupling control equation, establishing a grey box model by combining unscented Kalman filter with machine learning, performing combined state parameter estimation upon collected data to construct a state prediction framework, and predicting stiffness degradation at a running time scale. Response of a nonlinear multi-degree-of-freedom system can be predicted, and the residual stiffness of the gear is predicted through the collected data.
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
The present application provides a signal transmission method based on random unitary coding modulation and cross-domain iterative detection, including random unitary coding modulation at a signal transmitting end and cross-domain iterative detection at a receiving end. The random unitary coding modulation includes random unitary modulation or random unitary precoding, utilizing random unitary transformations to ensure that an equivalent channel matrix satisfies the correct right unitary invariance assumption. The cross-domain iterative detection includes using a cross-domain iterative receiver to receive a signal obtained after the random unitary coding modulation. The random unitary coding modulation ensures that general OAMP/VAMP, UAMP, and MAMP-type receivers achieve Bayesian optimal performance. The cross-domain iterative detection allows, through cross-domain detection, the receiver to utilize ultra-sparse time-domain channels, including low-complexity MAMP, OAMP/VAMP, and UAMP-type receivers.
A CVD online in-situ characterization system and method based on an absorption spectrum, which system and method belong to the technical field of semiconductor production devices. The CVD online in-situ characterization system comprises an absorption-spectrum detection apparatus, a spectrum movement and light-path calibration apparatus, and a tubular CVD device. By means of improving an existing tubular CVD device and in conjunction with the proposed environment compensation method, the accurate inspection of a chemical vapor deposition process in a high-temperature and low-pressure environment is realized; by means of real-time inspection, the pattern of a sample or a reaction system changing over time can be obtained; and in view of changes in the temperature and pressure of the system, the pattern of the sample or the reaction system changing over temperature and pressure is further obtained, such that optimal deposition conditions can be determined. In addition, by means of automatic light-path calibration, the system can inspect the deposition situation of the sample at any position in a quartz tube during the chemical vapor deposition process, such that an accurate growth window of the sample can be quickly determined.
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
C23C 16/00 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
12.
ASO FOR PREVENTION AND TREATMENT OF CANCER METASTASIS AND USE THEREOF
Provided are an antisense oligonucleotide (ASO) for prevention and treatment of cancer metastasis and a use thereof. The present disclosure specifically relates to an ASO or a pharmaceutically acceptable salt thereof, wherein the ASO specifically targets lncRNA GMAN, and the nucleotide sequence of the lncRNA GMAN is as shown in SEQ ID NO: 1. The provided ASO sequence targeting lncRNA GMAN can significantly inhibit invasion and metastasis of gastric cancer cells, and has huge potential to treat cancer and inhibit cancer metastasis.
A61P 35/04 - Antineoplastic agents specific for metastasis
13.
Application of Gastrodia elata Blume derived nano-extracellular vesicles in the preparation of drugs for the prevention and/or treatment of subarachnoid hemorrhage
The invention belongs to the field of biomedicine technology and discloses the application of Gastrodia elata Blume derived nano-extracellular vesicles in the preparation of drugs for the prevention and/or treatment of subarachnoid hemorrhage (SAH). The Gastrodia elata Blume-derived nano-extracellular vesicles of this invention are obtained from separation of Gastrodia elata Blume by water extraction. The ingredients of this invention are natural, none of toxic side effects and with good biocompatibility and safety. Therefore, this invention has broad application prospects. The invention uses Gastrodia elata Blume-derived nano-extracellular vesicles to conduct in vitro and in vivo experiments and finds that it can inhibit the activation of microglia after subarachnoid hemorrhage by inhibition of the transformation of microglia into M1 phenotype and promoting the transformation of microglia into M2 phenotypic transformation which has significant effect in treating SAH, and can be used to prepare drugs for preventing and/or treating subarachnoid hemorrhage.
Disclosed in the present invention are a resource allocation method and system. In microservice systems, resources are allocated to applications on the basis of user request information. The method comprises the following steps: acquiring a target optimization model, which comprises several optimization sub-models corresponding one-to-one to resources, wherein an optimization objective of the optimization sub-models is to minimize the sum of an average response time of all applications on corresponding resources, and variables of the optimization sub-models comprise decision variables and environment variables; acquiring environmental parameters corresponding to a current microservice system; and on the basis of the environmental parameters, solving the optimization sub-models in parallel according to an alternating direction method of multipliers, so as to obtain an optimal solution corresponding to each decision variable, thereby generating a corresponding resource allocation strategy. In the present invention, by means of solving the optimization sub-models in parallel, an optimal allocation result corresponding to each resource is obtained, and the average response time of each application is optimized.
The present invention belongs to the technical field of atomic layer deposition. Disclosed is a chemical vapor deposition automation device capable of realizing atomic-precision manufacturing. The device integrates a pressure system, a temperature system and a flow system, thereby realizing full-process automated control over a chemical vapor deposition process; in terms of pressure control, a valve experience opening angle is introduced, such that a target pressure can be quickly approached, thereby greatly shortening a response time; and a discontinuous angle control algorithm is further designed, such that relatively high control precision can also be achieved for large-pressure control during the chemical vapor deposition process. Moreover, the device is also provided with an in-situ characterization system, such that the real-time detection of a deposition condition of a sample during the chemical deposition process is realized by means of a corresponding apparatus. Furthermore, in the present application, a furnace moving track is provided, such that a furnace can be moved to thoroughly expose a heating area to the air during a cooling phase after a production process has been completed, thereby achieving the maximum cooling efficiency and improving the overall production efficiency.
Provided are a road traffic incident detection method, system and device based on small sample learning. According to the invention, traffic flow data and incident data are utilized to construct non-incident samples by a case contrast study method, traffic flow feature indexes are extracted to construct incident and non-incident sample feature sets, then sample division and pairing are performed on the feature sets to obtain training and test sample pair sets, a traffic incident detection model is constructed by adopting a twin network architecture in small sample learning, and the model is trained and tested by a sample pair mode. The invention is conductive to accurately detecting accidental traffic incidents, and providing supports for avoiding secondary accidents and improving the traffic safety level.
G06N 3/00 - Computing arrangements based on biological models
G06N 3/0442 - Recurrent networks, e.g. Hopfield networks characterised by memory or gating, e.g. long short-term memory [LSTM] or gated recurrent units [GRU]
The invention discloses a micro-metal tube thrombus elasticity detection device and method based on an L(0,1) longitudinal mode guided wave. The device includes a device housing, a temperature control module, a micro-metal tube, and a magnetostrictive assembly. The housing is externally connected to the temperature control module to realize internal constant temperature, the replaceable micro-metal tube is installed inside, the magnetostrictive assembly composed of a permanent magnet and a coil is provided at one end outside the tube. An L(0,1) longitudinal mode guided wave is excited on the micro-metal tube. When liquid viscosity within the tube changes, the energy attenuation of the guided wave propagating along the tube is different. The energy attenuation of the guided wave is defined through the attenuation rate of multiple echo peak values to reflect changes in the blood viscosity.
Disclosed in the present invention is an adaptive tensioning wearable monitoring device for livestock and poultry. A flexible loop band runs through an adaptive tensioning module and a monitoring module and is connected end to end in the adaptive tensioning module, a wireless sensing module is mounted on a surface of the monitoring module, the monitoring module is slidably connected to the flexible loop band, one end of the adaptive tensioning module is fixedly connected to a fixed end of the flexible loop band, and the other end of the adaptive tensioning module is retractably connected to a movable end of the flexible loop band. The adaptive tensioning module is arranged on the back of livestock and poultry, and when the flexible loop band is tightened, the wireless sensing module tightly fits against the skin in a livestock and poultry body temperature measurement area. In the present invention, the adaptive tensioning module is designed to be capable of adaptively adjusting the size of an apparatus as livestock and poultry grows, thereby solving the problem whereby livestock and poultry cannot wear a wearable apparatus for a long period of time during production, and solving the problems of causing great stress to livestock and poultry after long-term wearing of the apparatus, inaccurate body monitoring information, etc., such that the adaptive tensioning wearable monitoring device has great application prospects in the fields of health monitoring of livestock and poultry and wearable apparatuses for livestock and poultry.
A method for predicting a thermal error of a spindle of a computer numerical control (CNC) machine tool based on twin feature transferring of a virtual-real prototype, is provided, including: first, building a spindle physical prototype experiment table, and screening temperature sensitive points outside the physical prototype spindle, so as to establish an autoregressive distributed lag model; second, determining a temperature synchronization lag point on the physical prototype spindle corresponding to the temperature sensitive point outside the physical prototype spindle, so as to construct a thermal error analysis model; thereafter, establishing a virtual prototype and transferring the twin feature of the physical prototype, and by integrating a twin coupling relationship between the physical prototype spindle and the virtual prototype spindle, realizing the thermal error prediction. The present disclosure improves the accuracy of the thermal error prediction under the condition that it is difficult to arrange sensors on the spindle.
A method of double-contrast magnetic resonance fingerprinting including: optimizing, using Cramér-Rao lower bound (CRLB) via a computer system, radiofrequency (RF) pulse parameters in an MRF sequence; loading, via the computer system, the RF pulse parameters optimized into an MRI scanner; and capturing raw k-space data by selecting different signal contrast modules for dual-contrast encoding at varying repetition times (TR); reconstructing, via the computer system, at least one image including a plurality of pixels; defining, via the computer system, a dynamic range and step size for tissue parameters; and creating, via the computer system, a dictionary based on Bloch equations, the dynamic range, and the step size; and comparing, via the computer system, signal evolution for each of the plurality of pixels in the at least one image to the dictionary to determine quantitative parameters for each of the plurality of pixels, and generating a quantitative parameter map.
G01R 33/58 - Calibration of imaging systems, e.g. using test probes
G01R 33/56 - Image enhancement or correction, e.g. subtraction or averaging techniques
G01R 33/561 - Image enhancement or correction, e.g. subtraction or averaging techniques by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
Disclosed in the present invention are a DAG job scheduling method and system. The method is as follows: when a progress status of a job is updated, the following steps are executed: acquiring native feature data of each job; extracting embedding feature vectors from the native feature data on the basis of a graph convolutional neural network, and generating a status feature vector on the basis of an extraction result; inputting the status feature vector into a first prediction network, predicting, by the first prediction network, the scheduling probability of each candidate task, and obtaining scheduling priorities of candidate tasks; and according to the scheduling priorities from highest to lowest, sequentially selecting and allocating nodes for the candidate tasks on the basis of the status feature vectors, and generating a scheduling strategy on the basis of a selection result. The scheduling strategy provided in the present invention can globally improve the efficiency and can reduce the cache overhead of intermediate data during job execution.
The present invention relates to the technical field of pharmaceuticals, and provides an isoquinoline-5,8-dione tricyclic derivative, a preparation method therefor, and a use thereof. The isoquinoline-5,8-dione tricyclic derivative provided by the present invention is a compound represented by formula I. The compound comprises a stereoisomer, geometric isomer, tautomer, nitrogen oxide, hydrate, solvate, pharmaceutically acceptable salt or prodrug thereof. The compound has a relatively high pharmacological activity, a relatively good water solubility and drug-likeness, and can effectively treat and prevent infectious diseases, tumors, inflammatory diseases, respiratory diseases, autoimmune diseases, cardiovascular and cerebrovascular diseases, and other related diseases.
C07D 217/02 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ringAlkylene-bis-isoquinolines
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 453/06 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing iso-quinuclidine ring systems
C07D 471/02 - Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups in which the condensed system contains two hetero rings
Provided is a generalization generation method of industrial robot pose trajectories supporting changeable operation path points, which relates to the field of robot trajectory planning. The method includes: acquiring a plurality of groups of robot end pose trajectories; aligning time steps of the pose trajectories via a multi-dimensional dynamic time warping algorithm; constructing a Gaussian mixture model of robot pose trajectories in combination with a variational Bayesian method and an attitude quaternion tangent space mapping method; calculating reference pose trajectory distribution via a Gaussian mixture regression method; performing kernelized representation on pose trajectory distribution, and solving an optimal hyperparameter of a kernel function by minimizing a root mean square error of a reproduced reference trajectory; and generating the robot end pose trajectories adapted to the operation path points by updating the reference pose trajectory distribution.
A method for predicting machined surface roughness of parts based on attention and transfer learning is provided. The method includes the following steps: first, acquiring key physical signals that affect evolution of machined surface roughness of parts of a computer numerical control machine tool and constructing a signal feature matrix; inputting the respective signal feature matrixes into a machined surface roughness prediction model for training, and obtaining a trained machined surface roughness prediction model; constructing a machine tool single-index degradation model, determining a degradation trend of the current computer numerical control machine tool, and in different degradation stages of the degradation trend, performing network model transferring on the machined surface roughness prediction models by using a transferring method separately, so as to obtain the machined surface roughness prediction models in different degradation stages, and realize the machined surface roughness prediction in different degradation stages.
G06F 30/17 - Mechanical parametric or variational design
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
25.
MACROPHAGE-SPECIFIC CHIMERIC ANTIGEN RECEPTOR, CONTROLLABLE POLARIZED MONOCYTE/MACROPHAGE EXPRESSING THE RECEPTOR, AND PREPARATION METHOD AND USE THEREOF
Provided are a macrophage-specific chimeric antigen receptor, a controllable polarized monocyte/macrophage expressing the receptor, and a preparation method and application thereof, relating to the field of biotechnology. The present disclosure provides a chimeric antigen receptor, including an extracellular antigen binding domain, a transmembrane domain, and an intracellular activation domain linked in sequence, wherein the extracellular antigen binding domain includes a signal peptide and/or a scFv which can specifically recognize a GBM-specifically expressed cell membrane surface protein EGFRvIII; the transmembrane domain includes a CD8α, linking an extracellular antigen binding domain and an intracellular activation domain; the intracellular activation domain includes TIR, CD3ZETA or GM-CSFRα/β, promotes the polarization of macrophage into M1 type, introduces the chimeric antigen receptor in the present disclosure into the macrophage, endows the macrophage with the function of targeting and killing the GBM, and effectively promotes and maintains the M1 polarization state of the macrophage.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Disclosed are an anti-Helicobacter pylori compound and use thereof, which relate to the technical field of pharmaceuticals. The compound is a compound represented by formula I and further comprises a stereoisomer thereof, a geometric isomer thereof, a tautomer thereof, a nitrogen oxide thereof, a hydrate thereof, a solvate thereof, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compound exhibits a good effect in the treatment of Helicobacter pylori infection.
A61K 31/438 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring being spiro-condensed with carbocyclic or heterocyclic ring systems
A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
C07D 263/62 - Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems having two or more ring systems containing condensed 1,3-oxazole rings
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A DAG job scheduling method includes following steps when a progress state of a job is updated: acquiring native feature data of each of jobs; performing embedding feature vector extraction on the native feature data based on a graph convolution neural network, and generating state feature vectors based on an extraction result; inputting the state feature vectors into a first prediction network, and predicting scheduling probability of respective candidate tasks by the first prediction network to obtain scheduling priorities of the respective candidate tasks; and selecting allocation nodes for the candidate tasks sequentially in an order of the scheduling priorities from large to small based on the state feature vectors and generating a scheduling strategy based on a selection result. The scheduling strategy provided in the disclosure can improve efficiency globally and can also reduce caching overhead of intermediate data in a job execution process.
Disclosed are a cell membrane-based biological material for cross-species cell component delivery and a preparation method thereof. The biological material is based on cell membrane coating, and a cross-species cell component is delivered into a specific cell in a membrane fusion mode, so that the cross-species component stably plays a specific function, thus providing a new thought and strategy for intracellular delivery of cross-species immunogenic biological materials.
Disclosed are a biological material for delivering a specific cell-targeted metabolic system, a preparation method therefor, and an application thereof. The biological material delivers the specific metabolic system into a specific cell by membrane fusion on the basis of cell membrane coating, so that the systematic metabolic regulation effect on the specific cell is achieved, and a new thought is provided for the preparation and application of the biological material designed for systematic cell metabolism regulation strategies.
The present invention relates to a human body health detection method and apparatus based on skin temperature control. The human body health detection method comprises acquiring a skin temperature at a contact position; determining whether the skin temperature reaches a preset temperature threshold or not; in a case where the skin temperature does not reach the preset temperature threshold, generating a temperature adjustment instruction to change the skin temperature; in a case where the skin temperature reaches the preset temperature threshold, generating a light-emitting instruction, so that a light signal irradiates the skin at the contact position; acquiring a feedback signal of the skin at the contact position; and according to the skin temperature and the feedback signal, calculating physiological indexes. The present invention has the advantages that the skin temperature at the contact position is controlled, a stable temperature environment is provided for subsequent health detection, and the fluctuation interferences of the environmental temperature and the temperature of the human body itself are eliminated.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
31.
WEARABLE SKIN TEMPERATURE CONTROL AND HEAT DISSIPATION APPARATUS AND METHOD
Provided are a wearable skin temperature control and heat dissipation apparatus and method and a human body health examination system and method. The wearable skin temperature control and heat dissipation apparatus comprises a temperature control module (100) and a heat dissipation module (200). The wearable skin temperature control and heat dissipation apparatus has the following advantages: the skin temperature of a first contact position can be controlled by the temperature control module (100), so that a stable temperature environment is provided for subsequent health examination, thereby eliminating the interference caused by the fluctuation of the environment temperature and the temperature of the human body itself; the heat dissipation module (200) is in contact with the skin at a second contact position, so that waste heat generated by the temperature control module (100) is transferred to the skin position, thereby preventing the temperature control module (100) from being unable to stably work due to heat accumulation; the wearable skin temperature control and heat dissipation apparatus uses the skin for heat dissipation without using additional heat dissipation structure such as an air cooling structure, and thus features simple structure and small size, thereby facilitating integrated design; the noise is low, thereby meeting the use requirements of medical scenes; power supply is not needed for the heat dissipation module (200), so that the power consumption is low, thereby prolonging the working time of the wearable skin temperature control and heat dissipation apparatus.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
32.
MIXED TRAFFIC FLOW-ORIENTED VEHICLE ECO-DRIVING CONTROL METHOD AND ELECTRONIC DEVICE
A mixed traffic flow-oriented vehicle eco-driving control method and an electronic device are provided. The method includes: calculating a gathering wave speed and a dissipation wave speed at an intersection, and obtaining a farthest queue point position of a connected and autonomous vehicle at a downstream intersection and a time, acquiring predicted trajectories of the manual-driving vehicle; constructing and solving an optimal ecological reference trajectory planning model of the connected and autonomous vehicle, obtaining an acceleration curve of the connected and autonomous vehicle, and acquiring an ecological reference trajectory of the connected and autonomous vehicle; and setting a risk factor based on the predicted trajectories of the manual-driving vehicles, constructing a tracking target based on the risk factor and the ecological reference trajectory, using a model predictive control for solving, and obtaining a control input of the connected and autonomous vehicle.
The invention pertains to a master-slave teleoperation robot system utilizing force mixed reality, relevant to teleoperation robot technology. The system consists of a master robot linked to a mixed reality device, which receives point cloud information to create a virtual environment. The slave robot features a depth camera that captures point cloud data from the real environment, transmitting it to the master robot in real time. This point cloud information generates a virtual fixture, which produces virtual force applied to the slave robot. The virtual force interacts with the actual environmental forces acting on the slave robot, guiding the operator's behavior at the master side. The system addresses incorrect occlusion between the real dynamic robot and the virtual scene by blending virtual and real elements. Through mixed reality with force guidance and feedback, it minimizes the risk of potentially harmful collisions during operations.
An ultrasonic-assisted hydrogen peroxide sterilization method and device are provided. The sterilization device includes a vaporization chamber, which has an inlet at an upper side and an outlet at a lower side, and a packaging film can be extended into the vaporization chamber from the inlet and extended out of the vaporization chamber from the outlet. An ultrasonic atomizer is arranged at a top of the vaporization chamber, which is externally connected to a liquid storage tank through a pipeline with a valve, liquid hydrogen peroxide is stored in the liquid storage tank, and the liquid hydrogen peroxide is atomized into hydrogen peroxide steam through an ultrasonic atomizer vibrator. A slit nozzle is arranged at an atomization outlet of the ultrasonic atomizer, through which the hydrogen peroxide steam is sprayed on a surface of the packaging film in the vaporization chamber, thus achieving rapid sterilization of the packaging film.
A spherical designer electromagnetic surface plasmon open resonator is provided. The open resonator includes a resonator inner core and a resonator outer shell. The resonator inner core is located in an inner center of the resonator outer shell, and the resonator inner core and the resonator outer shell are coaxial. The disclosure provides a device that implements the superscattering function for incident waves in all incident directions and in all polarization directions, and a spherical open resonator is implemented. The scattering cross section of the disclosure can be more than five times greater than that of a metal sphere of the same size, and the operating frequency can be flexibly designed. By utilizing the characteristic that the scattering cross section of the spherical designer electromagnetic surface plasmon resonator is much greater than its own geometric cross section, the electromagnetic super-scattering device can be implemented.
222, D-galactose, and the like, and various administration modes such as pre-administration, simultaneous administration, or administration after modeling all show that the DNJ and the derivative thereof have good anti-senescence activity. In-vivo experiments show that DNJ can significantly delay the senescence of mice.
A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
A61K 31/4535 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
C07D 211/46 - Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
C07D 409/06 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
A61P 39/06 - Free radical scavengers or antioxidants
37.
NANOMATERIAL FOR PREVENTING TUMOR BONE METASTASIS, PREPARATION METHOD THEREFOR, AND USE THEREOF
The present invention relates to a nanomaterial for preventing tumor bone metastasis, a preparation method therefor, and use thereof. The present invention has discovered a spatiotemporal coupling interaction between tumor cells and osteoclasts, and provides a tumor-bone initial metastasis behavior-targeting strategy which can accurately prevent tumor metastasis on the basis of the source, and can avoid drug resistance and biochemical drug resistance. On this basis, the present invention designs a physical killing nanomaterial targeting tumor-osteoclast conjugates, the nanomaterial being a bone targeting group-modified nanovesicle encapsulating a carbonate compound and a phosphate compound. The nanomaterial can be effectively concentrated in bone tissue; when tumor cells are activated, the acid secretion function of tumor-related osteoclasts in nearby tumor-osteoclast conjugates which are in contact with the tumor cells triggers the carbonate compound to generate carbon dioxide gas and promotes the release of the phosphate compound, which forms calcium phosphate crystals with calcium ions so as to kill nearby tumor cells, thus achieving a specific very-early tumor metastasis inhibition effect.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 47/62 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
A copper-based composite metal oxide heat storage material surface-coated with spinel-type structural carriers and a preparation method thereof, in which the spinel-type carrier material is prepared by using a sol-gel method, and then the copper-based composite metal oxide heat storage material is obtained by forming a composite of the spinel-type carriers and copper oxide through a high-temperature solid-state method. The spinel-type structural material has good high-temperature thermal stability and chemical stability, and the spinel-type structural material employed as carriers is coated on surfaces of the copper-based metal oxide to effectively improve the high-temperature sintering of the copper-based heat storage material, thereby improving re-oxidation degree (near 100%) and reaction rate of the copper-based composite metal oxide heat storage material, and has a superior cyclic heat storage/heat release performance.
Disclosed in the present invention is the use of a recombinant protein CCL11 in the treatment of malignant pleural effusions. Specifically, the present invention provides a method for treating and/or relieving malignant pleural effusions by means of intrapleural injection of the recombinant protein CCL11. The present invention first found that CCL11 can relieve MPEs by means of increasing eosinophilic granulocytes in the thoracic cavity. An MPE animal model is constructed, and intrapleural injection of the recombinant protein CCL11 remarkably increases eosinophilic granulocytes in the thoracic cavity, and meanwhile, obviously relieves MPEs.
SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD. (China)
ZHEJIANG UNIVERSITY (China)
Inventor
Yang, Jiwen
Liu, Shuguang
Fan, Man
Shen, Changlin
Wang, Lifeng
Gao, Yuan
Wu, Dan
Kang, Liyi
Abstract
A gradient coil assembly and a magnetic resonance imaging system comprising a Z-axis gradient coil are provided. The gradient coil assembly comprises a Z-axis gradient coil. The Z-axis gradient coil comprising a first coil and a second coil, the first coil and the second coil being arranged along an axial direction of the Z-axis gradient coil. The first coil comprises a first subcoil and a second subcoil. The first subcoil and the second subcoil extend alongside each other. The second coil comprises a third subcoil and a fourth subcoil. The third subcoil and the fourth subcoil extend alongside each other.
A low-density liquid-phase chip for Gossypium hirsutum L. based on targeted capture sequencing and use thereof provided. The low-density chip includes 908 SNP loci, where among the 908 SNP loci, 329 loci are significantly related to important agronomic traits, such as fiber quality, yield, and disease resistance of Gossypium hirsutum L., 14 loci are common plant transgenic detection loci, and 565 loci are other loci. This chip is adapted for use of detection of transgenic components in Gossypium hirsutum L. varieties, resource evaluation and lineage identification, seed purity identification, and genetic improvement of major agronomic traits of Gossypium hirsutum L. varieties.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12Q 1/6874 - Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation [SBH]
42.
METHOD FOR REAL-TIME MONITORING AND PREDICTION OF STATE DURING PIPE BENDING PROCESS, AND DIGITAL TWIN SYSTEM
Disclosed in the present invention are a method for real-time monitoring and prediction of a state during a pipe bending process, and a digital twin system. A gyroscope, a force sensor, etc. are mounted on a bending die, a pressing die and other dies of a pipe bending device to implement real-time collection of data such as the position, speed and acceleration of each die, and a pressure and friction force between each die and a pipe; a displacement sensor is mounted on a wiper die to implement wrinkling monitoring; a camera is mounted above the pipe to implement pipe wall state collection; and a gyroscope is mounted on a tail end of a mandrel to implement unloading springback monitoring of the pipe. The collected state information of the dies of the pipe bending device and that of the pipe is processed by means of a data processing system, and is then subjected to spatio-temporal fusion by means of a spatio-temporal fusion conversion module based on multi-task learning, so as to realize the construction of a digital twin model, and finally realize real-time monitoring and prediction of a state during the pipe bending process. In the present invention, the states of dies of a pipe bending device and the bending state of a pipe can be collected, and real-time monitoring and prediction of a state during a pipe bending process can be realized, and thus the precision and pipe bending quality of the pipe bending device can be improved.
A folding wheelchair, comprising a backrest frame hingedly connected to the rear end of a cushion frame (11), wherein a support frame is foldably connected to the lower side of the cushion frame (11); the support frame comprises rear support rods (13); the rear support rods (13) gradually extend downwards from front to back; the front end of each rear support rod (13) is hingedly connected to the cushion frame (11) or a corresponding front support rod (12); an auxiliary rod (10) extending upwards is provided at the position of each rear support rod (13) deviating from the rear end; the backrest frame has vertical rods (2) extending downwards; the position of each vertical rod (2) deviating from the lower end is hingedly connected to the corresponding auxiliary rod (10); a fixing hook (3) is hingedly connected to the lower end of each vertical rod (2); each rear support rod (13) is provided with a component (4); each component (4) is provided with a recess portion (41) matching a hook portion (31) of the corresponding fixing hook (3); each fixing hook (3) is provided with an elastic member (33); when each hook portion (31) is located in the corresponding recess portion (41), the hook portion (31) abuts against the recess wall of the recess portion (41) under the action of the corresponding elastic member (33); and each vertical rod (2) is close to or in contact with the rear end surface of the corresponding component (4). The folding wheelchair has high structural strength and high stability when in use.
Provided is a self-adaptive identification method for nonlinear dynamic parameters of a reducer, which belongs to the design field of a reducer. The method includes: modeling a harmonic reducer corresponding to a flexible joint as a concatemer of a rigid reducer and an elastic torsion spring, and carrying out dynamic theoretical modeling and parameter variable independence processing on the concatemer to form a dynamic equation for parameter identification; giving an optimized motion trajectory to each joint of a robot and controlling the robot to act accordingly, acquiring relevant data needed for parameter identification based on a built-in torque sensor and double encoders inside the joint; using an offline identification algorithm to accurately identify a plurality of dynamic parameters of a collaborative robot considering joint flexibility and friction, and obtaining a minimum parameter set.
This application relates to the technical field of image data processing, and in particular, to an enhanced monitoring method for agricultural planting based on unmanned aerial vehicle (UAV) remote sensing. The method includes: obtaining a farmland grayscale image, from which a plurality of target pixel points are selected; next, obtaining a plurality of neighborhood blocks corresponding to each target pixel point, and then obtaining a credibility of each neighborhood block corresponding to the target pixel point, thereby selecting a plurality of main neighborhood blocks corresponding to the target pixel point; and obtaining a filtering weight of each main neighborhood block corresponding to the target pixel point, thereby deriving a farmland enhanced image from the farmland grayscale image.
Disclosed in the present invention is a preparation method for a water-loss-resistant ionic conductive gelatin hydrogel, including: adding a gelatin into deionized water for soaking and swelling, and then placing the gelatin in a water bath and carrying out magnetic stirring to obtain a gelatin solution; adding sodium pyrrolidone carboxylate into the gelatin solution to carry out treatment to obtain a gelatin-sodium pyrrolidone carboxylate mixed solution; and cooling the gelatin-sodium pyrrolidone carboxylate mixed solution at a certain temperature to obtain a gelatin-sodium pyrrolidone carboxylate hydrogel.
A hybrid drive omni-directional motion actuator based on an origami structure, comprising at least one actuating module. The actuating module comprises a columnar shell deforming based on the origami structure, an upper cover plate and a lower cover plate. The columnar shell is the origami structure derived from Waterbomb crease, and a cavity containing gas is formed inside the shell. The two ends of the cavity are open, and the openings are respectively connected with the upper cover plate and the lower cover plate for blocking the openings. The lower cover plate is provided with vent holes communicating with the cavity, and the upper cover plate and the lower cover plate are pulled by driving ropes arranged in a crossed manner. Through the cooperation of gas and tendon drive, the columnar shell can have deformations of contraction, bending and torsion, so that a single actuating module has omni-directional movement capability.
TECHNOLOGY INNOVATION INSTITUTE – SOLE PROPRIETORSHIP LLC (United Arab Emirates)
ZHEJIANG UNIVERSITY (China)
Inventor
Huang, Chongwen
Ji, Ran
Zhang, Zhaoyang
Bader, Faouzi
Al Hammadi, Ahmed
Debbah, Mérouane
Abstract
A three-dimensional (3D) superdirective antenna and optimization method is disclosed herein. The antenna includes: a multilayer substrate, several a plurality of radiating elements, and an excitation module. The several radiating elements are mounted on the multilayer substrate to form a 3D radiating element array. The excitation module includes an excitation circuit and a beamforming module that measures radiation fields generated by the array both with and without coupling effects. An embodiment may also generate a coupling matrix based on spherical wave coefficient expansion of the measured radiation fields and determine a superdirective excitation vector based on the coupling matrix. An embodiment may also excite the radiating elements using the excitation vector to generate a superdirective beam. Compared with existing antenna technology, embodiments disclosed herein may dynamically realize a superdirective beam in an alignment direction and demonstrate excellent performance in both directivity and realizable gain.
H01Q 3/26 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the relative phase or relative amplitude of energisation between two or more active radiating elementsArrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the distribution of energy across a radiating aperture
H01Q 21/06 - Arrays of individually energised antenna units similarly polarised and spaced apart
H04B 7/06 - Diversity systemsMulti-antenna systems, i.e. transmission or reception using multiple antennas using two or more spaced independent antennas at the transmitting station
49.
RAIL CROSS-SECTION PROFILE MEASUREMENT METHOD AND SYSTEM
QINGDAO QIUSHI INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (China)
ZHEJIANG UNIVERSITY (China)
Inventor
Cao, Yanlong
Shen, Lingfeng
Shou, Yejun
Zheng, Jiesi
Huang, Fang
Wang, Jing
Abstract
The present application relates to a rail cross-section profile measurement method and system. Target images are collected from multiple angles, the collected target images are reconstructed into a rail profile from the current camera perspective by means of an algorithm, the obtained rail profile from the current camera perspective is corrected into the current rail cross-section profile, the current rail cross-section profile is finally compared with a standard rail cross-section profile, and an error result between the profiles is displayed; an ROI automatic extraction algorithm based on light plane calibration parameters is designed to increase the speed of light stripe center extraction by three times, and additionally, a center locating-based spline interpolation method is proposed to eliminate bending distortion in intersection regions, thereby achieving rapid and accurate light stripe center extraction; and a cross laser stripe center extraction algorithm based on an RANSAC algorithm is used for removing background interference and classifying light stripes, thereby achieving efficient transformation from coordinates of light stripe feature points of a rail laser image to spatial three-dimensional coordinates.
G01B 11/25 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures by projecting a pattern, e.g. moiré fringes, on the object
50.
FIBER HAVING SPIRAL STRUCTURE AND METHOD FOR PREPARING SAME UNDER SELF-INITIATION
SHANXI ZHEJIANG UNIVERSITY NEW MATERIALS AND CHEMICAL RESEARCH INSTITUTE (China)
Inventor
Gao, Chao
Zhang, Yiwei
Chang, Dan
Abstract
A fiber having a spiral structure and a method for preparing same under self-initiation. The method comprises: extruding a graphene oxide spinning solution having a high degree of oxidation into a coagulating bath by means of a spinning head having a certain bevel angle, wherein a bevel cut leads to a difference in flow velocity between two sides of the spinning solution at an outlet, which results in unstable extrusion and the production of a fiber having a single-sided skirt structure. During the processes of pulling out the fiber from the coagulating bath and drying same, infrared illumination is applied to a single side of the fiber, resulting in spontaneous twisting of the fiber under the combined action of a solvent and interfacial tension, and therefore a self-twisting graphene oxide fiber is obtained. The self-twisting graphene fiber prepared by using the method is rich in spiral wrinkles and has the characteristics of high elongation, high strength, etc.; and in particular, the twisting process occurs spontaneously without an additional twisting and throwing device, and the twisting degree can be controlled by means of the bevel angle of the spinning head, the solidification intensity, the extrusion speed, the filament winding speed and the drying intensity, thereby achieving flexibility.
A paper folding structure-based omnidirectional mobile actuator featuring hybrid driving, said actuator comprising at least one actuating module, said actuating module comprising a columnar housing (1) that is deformable on the basis of a paper folding structure, an upper cover plate (7), and a lower cover plate (4). The columnar housing (1) is a paper folding structure derived on the basis of waterbomb creases. A cavity for containing gas is formed at the interior of the housing (1), the cavity is open at two ends, and the openings are connected to the upper and lower cover plates, respectively, for blocking the openings. A vent hole in communication with the cavity is formed on the lower cover plate (4), and driving strings arranged to cross one another are used for pulling between the upper and lower cover plates. By means of the cooperation between pneumatic driving and string driving, deformation by retraction, bending, and twisting can be generated on the columnar housing (1), such that the single actuating module is capable of omnidirectional motion. Moreover, there are numerous modes of motion, the number of actuating modules that the actuator includes can be adjusted as needed, modularization and reconstruction are facilitated, and high practical value and prospects of application are achieved in the fields such as soft robots and humanoid robot arms.
B25J 19/00 - Accessories fitted to manipulators, e.g. for monitoring, for viewingSafety devices combined with or specially adapted for use in connection with manipulators
52.
CONTINUOUS-WAVE PEROVSKITE POLARITON LASER DEVICE AND LASER CHIP
Disclosed in the present invention are a continuous-wave perovskite polariton laser device and laser chip. A gain medium of the continuous-wave perovskite polariton laser device is a perovskite material or a mixed material containing the perovskite material, and is in the form of a thin film, a microcrystal, fluorescent powder, a nanocrystal, a quantum dot or a single crystal. A perovskite gain medium is prepared by means of a solution method or a vacuum coating method, and by combining the perovskite gain medium with an optical resonant cavity, steady-state exciton-polariton condensation is formed by means of strong interaction between excitons and photons, and low-threshold continuous-wave polariton laser emission can be achieved without the need to meet conventional laser device population inversion conditions. The laser device can implement room-temperature low-threshold continuous-wave or pulse lase emission under various coherent and incoherent light sources or electrical excitation pumping, the threshold of the laser device is 1-3 orders of magnitude lower than the thresholds of conventional semiconductor laser devices, and the optimized threshold can reach 0.1-1 W/cm2 or below; and the laser device relates to a novel ultra-low power coherent light source technology.
A non-destructive fruit quality tap testing device based on pneumatic-electromagnetic combination. Two ends of a bellows support member (5) are respectively connected to a connecting plate (1) and a bellows (6); a pneumatic connector (2) is connected to the bellows support member (5); the bottom end of a support spring (27) is connected to the bottom end of the bellows support member (5); the top end of the support spring (27) is fixedly connected to the bottom end of an impactor casing cover (28); two ends of an impactor casing (17) are respectively connected to the impactor casing cover (28) and the bottom of the bellows (6); an insulating sleeve (22) is mounted inside the impactor casing (17); a hollow space for placing an electromagnetic coil (24) is present between the insulating sleeve (22) and the inner side wall of the impactor casing (17); a core (14) is provided inside the insulating sleeve (22); a sliding column (11) is movably connected to the interior of the core (14); two annular magnets (12, 15) are connected to two ends of the sliding column (11) by means of magnetic ring bases (10, 21); a sensor (16) is nested within a sensor base (20); and a flexible tapping head (19) is fixedly connected to the bottom of the sensor base (20). The device can be used for fruit quality testing, so as to implement fruit quality grading and standardization, thus improving the efficiency of supply chains, and increasing the added value of fruits.
A polarization controller based on on-chip mode conversion is provided. An input end-face coupler is connected to an input end of an input polarization-dependent mode converter through an input phase shifter. An output end of the input polarization-dependent mode converter is connected to an input end of a multi-mode 1×1 Mach-Zehnder interferometer (MZI), and an output end of the multi-mode 1×1 MZI is connected to an input end of an output polarization-dependent mode converter. An output end of the output polarization-dependent mode converter is connected to an output end-face coupler through an output phase shifter. The input end and the output end of the multi-mode 1×1 MZI are respectively connected to the input polarization-dependent mode converter and the output polarization-dependent mode converter to form a polarization insensitive beam splitting structure. The polarization controller can convert any two arbitrary polarization states, and has a compact structure and a large bandwidth.
G02B 6/27 - Optical coupling means with polarisation selective and adjusting means
G02B 6/293 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means
G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
55.
INTEGRATED ENERGY SYSTEM OPTIMIZATION CONTROL METHOD BASED ON PHYSICS-INFORMED NEURAL NETWORK
Disclosed in the present invention is an integrated energy system optimization control method based on a physics-informed neural network. The method comprises the following steps: S1, constructing a light-electricity-heat-gas integrated energy system optimization control model; S2, generating a node connection relationship matrix on the basis of a network topology structure of an integrated energy system; S3, constructing a deep graph neural network model for physical information fusion; S4, constructing a loss function of the deep graph neural network model for physical information fusion; and S5, training a physics-informed neural network model on the basis of historical operation data, and using the physics-informed neural network model for system optimization control. The present invention achieves optimization control of the state of an integrated energy system by relying on a light-electricity-heat-gas integrated energy system optimization control model, by means of an integrated residual, an optimization objective and various constraint conditions, and on the basis of a parallel mode of data driving and physical modeling, thereby effectively coping with the impact of the uncertainty of renewable energy and sudden accidents in the energy system, and ensuring the safe and stable operation of the integrated energy system.
G06Q 10/067 - Enterprise or organisation modelling
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
56.
SUBSTITUTED TRIFLUOROALKYL THIOALKYL BENZOTHIOATE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Disclosed in the present invention are a substituted trifluoroalkyl thioalkyl benzothioate derivative, and a preparation method therefor and the use thereof. The derivative has a structure as shown in a formula (I). Further disclosed in the present invention is the preparation method for the above-mentioned substituted trifluoroalkyl thioalkyl benzothioate derivative. The substituted trifluoroalkyl thioalkyl benzothioate derivative of the present invention has anti-inflammatory activity and neuroprotective activity, and can be used in the preparation and application of pharmaceuticals, foods or health care products related to anti-inflammation, neuroprotection, and anti-neurodegenerative diseases. The substituted trifluoroalkyl thioalkyl benzothioate derivative can also delay the aging process, prevent aging-related diseases, also has the effect of increasing the rate and density of hair growth, and thus can be used for developing pharmaceuticals, foods, health care products or personal care products, etc. aimed at anti-aging, and the prevention and/or treatment of alopecia.
C07C 327/26 - Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
C07C 69/88 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
C07C 69/94 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
C07C 69/92 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
C07C 69/84 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
A61K 31/235 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
A61K 31/085 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
A61K 31/222 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 25/00 - Drugs for disorders of the nervous system
A non-contact cardiogram measurement method is disclosed. The method includes: measuring, by a Doppler radar or a pulse radar, a distance change between the radar and a skin surface through an electromagnetic wave, a light wave and a sound wave; deriving a displacement curve indicating a change in a human heart volume; taking first-order and second-order derivations of the displacement curve to acquire velocity and acceleration curves; taking zero points and extreme points of the velocity and acceleration curves as velocity and acceleration information, and as characteristic points of different stages of atrial and ventricular systole and diastole; acquiring time, volume change, velocity and acceleration information of atrial and ventricular systole and diastole in a cardiac cycle. The present disclosure features low cost and low radiation hazard, avoids direct contact with the human body, and provides a convenient and easy way for daily cardiac diagnostic measurement of special patients.
The invention discloses a method for recycling and reprocessing of polyurethane foams based on acetoxime. The method comprises three steps: (1) Polyurethane foams are degraded into functionalized oligomers and/or small molecular compounds by adding acetoxime. (2) The obtained degradation products from step (1) are dispersed into acetoxime, and then are melted above the melting point of acetoxime, followed by being cooled down below the melting point of acetoxime, thus obtaining a mixture. (3) The mixture from step (2) is reprocessed into new polyurethane foams by vacuum sublimation. With this method, polyurethane wastes can be recycled and reprocessed into new foams and 3D printing products without consuming any reagent, or changing existing products and production infrastructures.
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
Jiaxing Research Institute, Zhejiang University (China)
Inventor
Zheng, Chenghang
Gao, Xiang
Zhou, Can
Zhao, Zhongyang
Yang, Chao
Weng, Weiguo
Zhang, Yongxin
Wu, Weihong
Tan, Chang
Li, Qinwu
Yu, Libin
Li, Lianming
Tian, Jianglei
Shao, Lingyu
Abstract
In an intelligent pollution and carbon reduction method based on combustion control and load distribution, a data processing layer, a multi-unit load distribution and operation optimization layer and a single-unit boiler multi-objective combustion optimization layer are used. The data processing layer, the multi-unit load distribution and operation optimization layer and the single-unit boiler multi-objective combustion optimization layer are embedded in a power plant information system in the form of modules. A load distribution and operation optimization method for a multi-source fuel blending combustion unit with economy as an objective is provided to overcome the operation optimization difficulty of the key production process of a multi-source fuel blending combustion cogeneration unit, such as sludge drying-steam distribution.
Disclosed are a correction system and method for eliminating non-uniform distribution of a light field during hyperspectral image acquisition, to effectively eliminate the impact of non-uniform light field distribution caused by halogen light illumination on acquisition of hyperspectral image information. The correction method includes acquiring hyperspectral images A corresponding to two standard whiteboards with different reflectance under illumination of a halogen light source. A hyperspectral image B is acquired corresponding to a tea leaf sample under illumination of the same light source. Spatial distribution characteristics of a light field are obtained based on the hyperspectral images A. Pixels in the hyperspectral images A and B are spatially matched. Light field correction is performed on a pixel of the sample in the hyperspectral image B, and reflectance correction is performed on the sample after the light field correction.
Technology Innovation Institute - Sole Proprietorship LLC (United Arab Emirates)
Inventor
Huang, Chongwen
Ji, Ran
Zhang, Zhaoyang
Bader, Faouzi
Al Hammadi, Ahmed
Debbah, Mérouane
Abstract
A three-dimensional (3D) superdirective antenna and optimization method is disclosed herein. The antenna includes: a multilayer substrate, a plurality of radiating elements, and an excitation module. The several radiating elements are mounted on the multilayer substrate to form a 3D radiating element array. The excitation module includes an excitation circuit and a beamforming module that measures radiation fields generated by the array both with and without coupling effects. An embodiment may also generate a coupling matrix based on spherical wave coefficient expansion of the measured radiation fields and determine a superdirective excitation vector based on the coupling matrix. An embodiment may also excite the radiating elements using the excitation vector to generate a superdirective beam. Compared with existing antenna technology, embodiments disclosed herein may dynamically realize a superdirective beam in an alignment direction and demonstrate excellent performance in both directivity and realizable gain.
H01Q 9/16 - Resonant antennas with feed intermediate between the extremities of the antenna, e.g. centre-fed dipole
H01Q 21/06 - Arrays of individually energised antenna units similarly polarised and spaced apart
H01Q 21/24 - Combinations of antenna units polarised in different directions for transmitting or receiving circularly and elliptically polarised waves or waves linearly polarised in any direction
62.
OPTIMIZATION CONTROL METHOD FOR INTEGRATED ENERGY SYSTEM BASED ON PHYSICAL-INFORMED NEURAL NETWORK
The present disclosure discloses an optimization control method for an integrated energy system based on a physical-informed neural network, which comprises the following steps: S1, constructing an a solar-electricity-heat-gas integrated energy system optimization control model; S2, generating a node connection relation matrix based on the network topology structure of the integrated energy system; S3, constructing a deep graph neural network model with physical-informed fusion; S4, constructing a loss function of the deep graph neural network model with physical-informed fusion; and S5, training a physical-informed neural network model according to the historical operation data to be used for system optimization control. The present disclosure can effectively deal with the influence of uncertainty of renewable energy and unexpected situations on the energy system, thereby ensuring the safe and stable operation of the integrated energy system.
G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
G05B 13/04 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric involving the use of models or simulators
Disclosed is a heterogeneous three-dimensional observation registration method, medium, and device based on depth phase correlation. The disclosure optimizes the phase correlation algorithm into a globally convergent differentiable phase correlation solver, and combines the solver with a simple feature extraction network, thereby a heterogeneous three-dimensional observation registration method whose overall framework is differentiable and capable of end-to-end training is established. The disclosure can achieve accurate three-dimensional observation registration for three-dimensional objects, scene measurements, and medical image data; and the registration performance is higher than the existing baseline model.
A high-content stretchable silica aerogel composite fiber, prepared by the following method: 1) preparing a silica aerogel composite fiber precursor by means of coaxial melt spinning; 2) thermally stretching the silica aerogel composite fiber precursor; and 3) hot-pressing and sealing fibers into bamboo joints. Silica aerogel composite fibers of different diameters can be prepared by adjusting the diameter of the hollow fiber, and the warmth retention properties of the fiber can still be kept unchanged after 10,000 times of cyclic stretching with 100% strain.
QINGDAO QIUSHI INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (China)
ZHEJIANG UNIVERSITY (China)
Inventor
Cao, Yanlong
Wei, Xiaoyao
Zhou, Wentao
Liu, Wenyuan
Huang, Fang
Ding, Binjie
Wang, Jing
Abstract
The present application relates to a weld seam surface defect detection method and system. The weld seam surface defect detection method comprises: performing multi-angle and multi-surface acquisition of target surface images; then, reconstructing normal maps of the target surface images by means of a high-performance algorithm, and clarifying normal features of defects; and finally, on the basis of the surface normal features, aiming at transverse texture defects and height mutation defects, respectively designing a transverse texture defect detection algorithm based on two stages and rotated rectangle extraction and a height mutation defect detection algorithm based on adaptive dual-threshold segmentation. The present application overcomes texture noise and pseudo-defect interference of ground surfaces, effectively solves the problems of difficulty in feature extraction and positioning of ground surfaces of steel rail weld seams, and has the system operating efficiency superior to that of existing detection methods, thus satisfying requirements of actual production.
Disclosed in the present invention are a molecular sieve with a point screening structure, and a preparation method therefor and the use thereof in adsorption and separation of propylene and propane. The molecular sieve of the present invention is formed by bonding 1,2-ethane disulfonate anions, 4,4'-dipyridyl sulfide and Cu2+2∞∞, wherein M represents Cu2+22; and the molecular sieve in the present invention has local point-like pore channel shrinkage. The preparation method comprises: mixing a Cu2+ source, 1,2-ethane disulfonate and 4,4'-dipyridyl sulfide in a reaction solvent for reaction to obtain the molecular sieve with a point screening structure. The present invention has the outstanding advantages of good material stability, high adsorption selectivity, high adsorption capacity, high adsorption rate, easy regeneration, etc., and has a good industrial application prospect.
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography
B01J 20/30 - Processes for preparing, regenerating or reactivating
67.
High-resolution magnetic resonance fingerprinting method and device based on radio frequency encoding
The present invention is a high-resolution magnetic resonance fingerprinting method based on radio frequency encoding, a device and storage medium, where radio frequency encoding is introduced into MRF, n time evolution signals can be collected by designing and respectively scanning a set of n radio frequency pulse signals, separate time evolution signals representing n sub-slices can be obtained after decoding and calculating according to a encoding process, and then separate quantitative images of the n sub-slices can be obtained through dictionary matching. Compared with conventional MRF, a slice resolution of the quantitative images obtained in the imaging method of the present invention is increased by n times and a signal-to-noise ratio is not reduced. Through a phantom experiment and a human experiment, accuracy of quantitative effect and an effective improvement of the resolution of the present invention are proved, and the present invention can provide higher-resolution quantitative imaging results.
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
G01R 33/50 - NMR imaging systems based on the determination of relaxation times
G01R 33/56 - Image enhancement or correction, e.g. subtraction or averaging techniques
G01R 33/561 - Image enhancement or correction, e.g. subtraction or averaging techniques by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
Disclosed are a nano-material for generating ATP and NADPH under red light excitation and a preparation method thereof. By I extracting and nanocrystallizing a plant-derived thylakoid, a nano-thylakoid is obtained, and ATP and NADPH are generated, which are respectively used to enhance biological energy metabolism and substance metabolism, maintain cellular homeostasis, and realize a variety of engineering designs, thus providing a new thought for the preparation and application of biological energy and substance metabolism regulation materials.
Disclosed are a four-degree-of-freedom micro surgical robot with a remote center of motion and a control system. The surgical robot comprises a movable platform mechanism and at least two branch-chain mechanisms that are formed by means of planar processing of a composite layered material. The movable platform mechanism comprises a central connecting rod with a polygonal plane and branch-chain connecting rods connected to side edges of the central connecting rod by means of hinges. The central connecting rod serves as a movable platform for installing surgical instruments. Both the number of the branch-chain connecting rods and the number of sides of the polygon are not smaller than the number of the branch-chain mechanisms. All the branch-chain mechanisms are in the same form, and each of the branch-chain mechanisms is formed by splicing an upper branch chain and a lower branch chain. The four-degree-of-freedom micro surgical machine can meet the requirements of high-degree-of-freedom, high-precision, and large-range operations, reduce the size, weight, and manufacturing costs of a micro operation device, and achieve a complex four-degree-of-freedom operation of rotation and in-situ translation, and has a ten-micrometer-level operation precision and a ten-cubic-centimeter-level operation space.
The present disclosure provides a freezing transfer method for porous carbon electrodes based on subzero temperature and applications in sensors, the method including: forming porous carbon electrodes to be transferred on a substrate, introducing a hydrogel material between the porous carbon electrodes to be transferred and a flexible/elastomeric material, expanding the hydrogel material to form a structural coupling with porous carbon, removing the substrate to realize peeling, and completing the transfer of the porous carbon electrodes. According to the present disclosure, fast and complete peeling of the porous carbon electrodes can be realized, a thinner flexible-elastomeric substrate is required, and a composite electrode formed has superior electroconductive stretchability, which helps to realize manufacturing of conformal flexible electronics such as ultrathin flexible or stretchable sensors.
Zhejiang Construction Investment Group Co., Ltd (China)
Hangzhou Hyperchain Technology Co., Ltd. (China)
Qi An Xin Technology Group Inc. (China)
Inventor
Han, Song
Wang, Zhibo
Jin, Rui
Chen, Xiaofeng
Xia, Wei
Abstract
The present invention discloses a method for private set intersection in a smart city system, a device, and a storage medium. According to the present invention, a threshold secret sharing technology is adopted to share a private set among three parties, so that an intersection cardinality is hidden and security of private set intersection is improved. Before two parties perform the private set intersection, a blockchain is used to verify identities of the two parties, which protects security of data of the two parties to a certain extent. In addition, according to the present invention, the private set is divided into a plurality of subsets with labels, which implements an interaction manner with finer granularity. Therefore, compared with a private set intersection solution in a previous smart city system, the present invention is greatly improved in practicability, security, and other aspects.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
72.
DYNAMIC HUMAN MODELING METHOD BASED ON THREE-DIMENSIONAL GAUSSIANS
Disclosed in the present invention is a dynamic human modeling method based on three-dimensional Gaussians. In the present method, a multi-view human video is given firstly, and in order to correct and transform the dynamic human appearance, a latent code and a set of blend weights are added to each Gaussian; and the latent code and a target pose are inputted to an MLP to correct the Gaussian in a canonical space, so as to capture an appearance change under the target pose. The corrected Gaussian is transformed into the target pose by means of the blend weights thereof in a linear blend skinning (LBS) manner. Finally, a realistic human image at a new viewing angle or a new pose can be rendered in real time by means of Gaussian splatting. Compared with an existing method based on an implicit neural radiance field (NeRF), the three-dimensional Gaussian representation of the present invention can better capture high-frequency details while achieving optimal rendering performance.
An SDF function-based robotic arm collision detection method. The method is divided into an offline stage and an online stage. The offline stage comprises: constructing an SDF function for describing the reachability of an end effector of a robotic arm; constructing an SDF function for describing a geometric shape of each link of the robotic arm; constructing an SDF function for describing spatial geometric information of the working environment where a robot is located; and extracting the geometric boundary of the part of the robot's reachable space intruded by an environmental obstacle. The online stage comprises: querying a symbol value of a target pose in the SDF function for describing the reachability of the end effector of the robotic arm, to determine whether the target pose is reachable or not; calculating a transformation matrix of each link coordinate system relative to a robot base coordinate system; and for each point in the geometric boundary, transforming the point into each link coordinate system, and querying a symbol value of the point in the SDF function for describing the geometric shape of each link, to determine whether the point collides with the link or not. The time of the collision detection stage with the maximum time consumption proportion in the robotic arm trajectory planning process can be greatly shortened, and the trajectory planning performance is improved.
The invention discloses a liquid-liquid extraction method for separating carboxylate monofunctional perfluoropolyethers and carboxylate difunctional perfluoropolyethers, which comprises: the mixture containing monocarboxylate end-group perfluoropolyether and dicarboxylate end-group perfluoropolyether are mixed in contact with light and heavy two-phase solvent, after extraction equilibrium, the two phases were separated and the solvent is removed, and the high-purity monocarboxylate end-group perfluoropolyether is obtained in heavy phase and dicarboxylate end-group perfluoropolyether is obtained in light phase. The light phase solvent comprises a diluent and a polar solvent containing fluorine atoms. The diluent is one or more of sulfolane, dimethyl sulfoxide, N-methylpyrrolidone, N,N-dimethylformamide, water, ethylene glycol, acetonitrile, acetic acid, ethanol, methanol. A heavy phase solvent consists of a non-polar solvent containing fluorine atoms and a polar solvent containing fluorine atoms, or a non-polar solvent containing fluorine atoms and a non-polar solvent without fluorine atoms.
The provided is a LiDAR odometry using a piecewise linear continuous-time trajectory. The LiDAR odometry includes the following steps: dividing an initial LiDAR point cloud time sequence through time windows to obtain LiDAR point cloud subsequences in the multiple time windows, and constructing an initial local point cloud map; and optimizing, based on the initial local point cloud map, a LiDAR pose for the LiDAR point cloud subsequence in each time window to obtain an overall continuous-time trajectory and a final local point cloud map. The provided achieves high-precision motion estimation of the LiDAR, with high robustness and real-time performance, and is suitable for fields such as robot navigation, simultaneous localization and mapping, and autonomous driving. The provided gives a simple and efficient solution that effectively utilizes the characteristics of the LiDAR as a streaming sensor.
HUZHOU PLANT PROTECTION QUARANTINE AND FERTILIZER MANAGEMENT STATION (China)
Inventor
Zhu, Zengrong
Lv, Jin
Yuan, Xin
Zhou, Wenwu
Qian, Ping
Wu, Wendi
Abstract
The present disclosure relates to the field of artificial honeycombs, in particular to an artificial nest for solitary bees and an application method of the artificial nest. The artificial nest comprises a main enclosure tube, hanging rings, a plurality of trapping hollow tubes and tightening mechanisms used for clamping the trapping hollow tubes. The hanging rings are arranged at an outer sidewall of the main enclosure tube. The tightening mechanisms are annularly arranged at an inner sidewall of the main enclosure tube, and the trapping hollow tubes are fixed in a ring of each tightening mechanism in an axis direction of the main enclosure tube. Each tightening mechanism comprises a connecting steel wire and fastening springs. The sidewall of the main enclosure tube is provided with fixing holes for fixing the tightening mechanisms.
Disclosed in the present invention is a method for decoding Chinese character writing for an invasive brain-computer interface. In a practical application, a corresponding motor neural signal is divided into two states of a writing stroke and a writing stroke break in view of inconsistency of the writing stroke and the writing stroke break during Chinese character writing, and different filters are trained. A hidden markov model (HMM algorithm) and a Viterbi algorithm are used to judge a task state of the motor neural signal, and the corresponding signal is put into a corresponding decoder. The present invention effectively reduces influence of difference of neural data in different states on the decoder, and improves the performance and robustness of the decoder.
Disclosed in the present invention is a LiDAR odometer method using a piecewise linear continuous time trajectory. The present invention comprises the following steps: first, using a time window to divide an initial LiDAR point cloud time sequence so as to obtain LiDAR point cloud sub-sequences under a plurality of time windows, and constructing an initial local point cloud map; and then, on the basis of the initial local point cloud map, optimizing LiDAR poses of the LiDAR point cloud sub-sequences under the time windows to obtain an overall continuous time trajectory and a final local point cloud map. The present invention achieves high-precision motion estimation for LiDARs, has high robustness and real-time performance, is applicable to the fields such as robot navigation, simultaneous localization and mapping, automated driving, and provides a relatively simple and efficient solution that can effectively handle the characteristics of LiDARs as streaming sensors.
G01S 7/48 - Details of systems according to groups , , of systems according to group
G06T 7/73 - Determining position or orientation of objects or cameras using feature-based methods
G06T 7/207 - Analysis of motion for motion estimation over a hierarchy of resolutions
G01S 17/88 - Lidar systems, specially adapted for specific applications
G01C 22/00 - Measuring distance traversed on the ground by vehicles, persons, animals or other moving solid bodies, e.g. using odometers or using pedometers
79.
CHINESE CHARACTER WRITING DECODING METHOD FOR INVASIVE BRAIN-MACHINE INTERFACE
Disclosed in the present application is a Chinese character writing decoding method for an invasive brain-machine interface. The method comprises: acquiring original motor neural signals, and processing same to obtain ESA neural signals; standardizing the ESA neural signals, and performing division to obtain a training set and a test set; dividing the training set into a handwriting stroke data set and a handwriting stroke pause data set; training a filter for decoding strokes and a filter for decoding stroke pauses, and training a state discriminator for discriminating between stroke writing and stroke writing pauses; inputting data of the test set into the state discriminator, inputting discriminated stroke writing state neural data into the filter for decoding strokes, and inputting discriminated stroke writing pause state neural data into the filter for decoding stroke pauses; and concatenating decoded stroke data and decoded stroke pause data, so as to obtain a final decoded Chinese character. In the present application, the inconsistency between stroke writing and stroke writing pauses during Chinese character writing is taken into consideration, corresponding motor neural signals are divided into two states, i.e., stroke writing and stroke writing pauses, and different filters are trained, thereby effectively reducing the impact of the differences in neural data in different states on a decoder, and improving the performance and robustness of the decoder.
Disclosed in the present invention are a compound represented by formula (I) or (II) or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a use thereof. The compounds have significant inhibitory activity on drug-resistant tumor cells having high expression of P-glycoprotein, and have a relatively strong effect of reversing multidrug resistance of tumor cells, and some of the compounds have significantly superior inhibitory activity on P-glycoprotein than Tariquidar, a third-generation P-glycoprotein inhibitor, and have relatively small cytotoxicity. In addition, the compounds can selectively inhibit P-glycoprotein on intestinal epithelial cells, and when orally administered in combination with an anticancer agent that is not easily absorbed in the digestive tract due to the inhibitory effect of intestinal P-glycoprotein, the compounds can improve the bioavailability of the anticancer agent.
C07D 491/048 - Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
A61K 31/498 - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
A61K 31/4355 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
An anti-NY-ESO-1 nanobody and a use thereof, relating to the field of immunology. The anti-NY-ESO-1 nanobody has specific recognition and binding capabilities for the NY-ESO-1 antigen. The nanobody has a minimum affinity constant of 68.1 nM, which shows that the nanobody has highly specific binding activity. It is expected that the nanobody will be used in the treatment of tumors expressing NY-ESO-1, or in diagnostic detection of an NY-ESO-1 protein.
C07K 16/30 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
A bispecific antibody targeting intracellular NY-ESO-1 and the use thereof, which relate to the technical field of biomedicine. A bispecific antibody targeting intracellular NY-ESO-1 is designed, in which the symmetrical form enables the complete molecular structure of a CD3 monoclonal antibody to be retained, and meanwhile, a nanobody sequence against NY-ESO-1157-165/A02 is added at the N terminus, so that two different antigens can be specifically recognized. The provided bispecific antibody is target-dependent, can significantly induce the upregulation of the early and late activation markers of T cells, and has significant anti-tumor activity in vivo with specificity.
The present invention provides a single-cell transcriptome sequencing method and use thereof. The method comprises: preparing a single-cell suspension with a test cell sample, then fixing cells with a fixative solution; and using a reverse transcription primer to perform an in-situ reverse transcription reaction on RNA of the fixed single cell to synthesize a first cDNA strand.
Disclosed are an oxidation-responsive water-soluble cationic pillararene, and a preparation method and application thereof, the oxidation-responsive water-soluble cationic pillararene is a cyclic small-molecule nucleic acid vector, and is obtained by quaternization reaction of 4-methylborate and tertiary amine-modified pillararene. According to the invention, a delivery vector with a high positive charge density is obtained through small molecule synthesis, the delivery vector is capable of being tightly complexed with negatively charged nucleic acid substances to form a nano-composite, and after the nano-composite enters cells, vector positive charges fall off to release the nucleic acid substances in an oxidation environment, and nucleic acid is efficiently translated and expressed. The delivery vector has the characteristics of simplicity and convenience in synthesis, high delivery efficiency and good biological safety, and has a good application prospect.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
85.
OXIDATION-RESPONSIVE CATIONIC WATER-SOLUBLE PILLARARENE, AND PREPARATION METHOD AND USE
Disclosed are an oxidation-responsive cationic water-soluble pillararene, and a preparation method and a use. The oxidation-responsive water-soluble cationic pillararene is a cyclic small-molecule nucleic acid carrier and is obtained by carrying out quaternization reaction on 4-methyl borate and a tertiary amine modified pillararene. A delivery carrier having a high positive charge density is obtained by means of small molecule synthesis, the delivery carrier can tightly bind with a negatively-charged nucleic acid substance to form a nanocomposite, and after entering cells, in an oxidative environment, positive charges of the carrier fall off and the nucleic acid substance is released to efficiently express nucleic acid information.
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
86.
POST-QUANTUM CRYPTOGRAPHIC ALGORITHM PROCESSOR AND SYSTEM-ON-CHIP COMPRISING SAME
Disclosed in the present invention are a post-quantum cryptographic algorithm processor and a system-on-chip comprising same. The post-quantum cryptographic processor comprises an instruction fetch unit, a decode unit, an execute unit and a write-back unit; the execute unit comprises a parallel computing unit module, and the parallel computing unit module uses a part recomposition technology and an operator fusion technology and thus can use a same part to realize core operation of different computing types and bit widths of a post-quantum cryptographic algorithm; the system-on-chip for running the post-quantum cryptographic processor comprises: a system bus, the post-quantum cryptographic processor connected to the system bus, a storage unit connected to the post-quantum cryptographic processor, an external device interface connected to the system bus and a cache active prefetching/pre-storing data functional module which is connected to the post-quantum cryptographic processor and is combined with a DMA; and the post-quantum cryptographic processor communicates with an external device by means of the external device interface, and performs data and instruction read/write on the storage unit. The present invention reduces the power consumption and resource overhead of systems, and improves the running speed of a post-quantum cryptographic algorithm.
The present invention relates to the technical field of seabed core triaxial tests. Disclosed is a deep-sea fidelity core triaxial test device suitable for a ship-borne laboratory. The deep-sea fidelity core triaxial test device comprises a sample transfer system and a triaxial main unit system. A sample that meets the length requirements for a triaxial test is stored in the sample transfer system, and a ball valve is closed to preserve the high-pressure environment of the sample; and the sample is released from a tube by means of a tube-releasing piston and is then sent into a triaxial test system, and is subjected to a triaxial test in a rubber cylinder, thereby obtaining the mechanical properties of a deep-sea energy soil reservoir sample. The device of the present invention is convenient to carry on a scientific research ship and convenient to connect to the existing natural gas hydrate sample pressure-maintaining transfer system, and a fidelity triaxial test is carried out immediately after a natural gas hydrate sample is obtained, thus having significant scientific research benefits.
yzz, wherein M is one or more of Co, Zn, Ni, Zr, Cu, Cr and Mg, and y and z are real numbers. When the modifier is added to a thermochemical heat storage material, during the process of forming a modified heat storage material, no by-product is generated, and the growth of crystals on the surface of the thermochemical heat storage material can be inhibited while the heat storage performance of the thermochemical heat storage material is ensured, thereby improving the anti-sintering capability of the thermochemical heat storage material and also enhancing the stability of the thermochemical heat storage material during long-term cycling in a high-temperature environment.
A method for extracting and identifying a polysaccharide from a complex sample. The method includes: subjecting a complex sample to be treated to sterilization and enzyme deactivation to obtain a system, and subjecting the system to solid-liquid separation to obtain a sterilization and enzyme deactivation-treated solution; deproteinizing the sterilization and enzyme deactivation-treated solution to obtain a deproteinized solution; purifying the deproteinized solution by using a hydrophilic lipophilic balance-solid phase extraction (HLB-SPE) cartridge to obtain a purified solution; subjecting the purified solution to alcohol precipitation to obtain the polysaccharide; and subjecting the polysaccharide to methylation, glycoside residue derivatization and liquid chromatography-mass spectrometry (LC-MS) analysis in sequence.
ZHEJIANG JUHUA NEW MATERIAL RESEARCH INSTITUTE CO., LTD. (China)
Inventor
Yang, Qiwei
Zhang, Wenjun
Ren, Qilong
Zhou, Liyang
Wang, Shuhua
Qin, Wei
Li, Hongfeng
Zhang, Zhiguo
Bao, Zongbi
Su, Baogen
Abstract
Provided is a method for producing tetrafluoromethane through plasma pyrolysis of waste polytetrafluoroethylene (PTFE), relating to the technical field of waste recycling. The method of the disclosure includes: subjecting the waste PTFE to a plasma pyrolysis reaction to obtain a pyrolysis product, and subjecting the pyrolysis product to quenching and gas-solid separation in sequence to obtain a pyrolysis gas including the tetrafluoromethane, wherein the plasma pyrolysis reaction is performed at a temperature of 1,800 K to 5,000 K. The method provided by the disclosure has advantages such as a high conversion rate, a short reaction time, a large treatment capacity, high reaction safety, easy product purification, and suitable for continuous industrial scale-up, and can realize the recycling of waste PTFE with a low energy consumption and a low cost. In addition, the method of the disclosure avoids the fluorine waste caused by incineration and leads to a high value-added tetrafluoromethane product.
C01B 32/10 - Carbon fluorides, e.g. [CF]n or [C2F]n
C08J 11/12 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by dry-heat treatment only
91.
Multi-modal robot system capable of realizing autonomous submarine docking and reconstruction
A multi-modal robot system capable of realizing autonomous submarine docking and reconstruction, includes a non-contact charging platform, several functional modules and a docking robot, wherein a coil is arranged on the non-contact charging platform, and energy and signals are transmitted between the coil and the functional modules; each of the functional modules includes a propeller module, an energy module, an observation detection module, an operation tool module, a navigation control module, a bow detection module and a tail propulsion module; and according to an instruction of a docking and reconstruction task, the docking robot reconstructs a multi-modal underwater robot by docking specific functional modules. The multi-modal robot system of the present invention can reconstruct the operation modal of the robot according to actual needs, realize the reconstruction and assembly of the underwater robot with three motion modes of horizontal plane cruise, fixed-point operation and vertical profiling, and reduce cost.
A safety management and control system for full lifecycle of industrial control data, comprising: an administrator terminal holding an administrator public-private key pair and an administrator public key root certificate; a server comprising an encrypted database kernel and an initializer, the encrypted database kernel is located in a trusted execution environment and contains industrial control data; the initializer is configured to initialize the encrypted database kernel in combination with the administrator public key root certificate sent by the administrator terminal when the server is deployed for the first time, and return a self-signed certificate generated by the server to the administrator terminal; and a client that accesses the system through the certificate issued by the administrator terminal, and interacts with the server for industrial control data within the authority configured by the administrator terminal.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
A neural network on-chip mapping method and apparatus based on a tabu search algorithm are provided. The method includes: constructing a tabu search table and using a heuristic-based iterative search process to select local computing cores of a network-on-chip as candidates, establishing an integer programming model and solving an optimal solution, continuously reducing an objective cost function of a mapping solution by loop iteration, and finally obtaining an approximately optimal deployment scheme.
The present invention relates to the field of image processing technology, specifically to a method, medium, and device for estimating the length of pipeline cracks based on video images. The method comprises the steps of A, extracting images with cracks from acquired pipeline videos, and making them into a dataset; B, establishing a segmentation model to segment the images in the obtained dataset to obtain crack images containing only cracks; C, marking the crack image to obtain the center coordinate of the crack images; D, obtaining the coordinate of all the pixels on the crack from the crack image, and calculating the length of the crack based on the obtained coordinates of the center and all pixels on the crack. This invention can overcome the challenges of quantifying crack length caused by the shooting angle, enabling the measurement of crack length on the inner wall of the pipeline using only pipeline inspection images. This significantly improves the accuracy of crack length quantification and provides a reference basis for further repair of drainage pipelines.
G06T 7/174 - SegmentationEdge detection involving the use of two or more images
G06T 7/62 - Analysis of geometric attributes of area, perimeter, diameter or volume
G06T 7/73 - Determining position or orientation of objects or cameras using feature-based methods
G06V 10/26 - Segmentation of patterns in the image fieldCutting or merging of image elements to establish the pattern region, e.g. clustering-based techniquesDetection of occlusion
G06V 10/52 - Scale-space analysis, e.g. wavelet analysis
G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
METHOD FOR ACHIEVING REMEDIATION OF CHLORINATED ORGANIC POLLUTANT-CONTAMINATED SOIL AND REDUCTION OF METHANE EMISSION SYNCHRONOUSLY THROUGH MICROBIAL REGULATION
A method for achieving a remediation of a chlorinated organic pollutant (COP)-contaminated soil and a reduction of a methane emission synchronously through a microbial regulation is provided, including: in an anaerobic environment, adding at least one of electron donors, electron shuttles, and electron flow interference agents to the COP-contaminated soil to accurately and directionally regulate an electron transfer route, facilitating a COP reductive dechlorination mediated by indigenous microorganisms and meanwhile inhibiting a growth and a metabolism of methanogens synchronously. Electron donors are added as a carbon source to promote microbial growth and metabolism under anaerobic conditions, electron shuttles such as biochar are added to accelerate the transfer of electrons from the donor to the acceptor, and the electron flow interference agents such as a methanogenic inhibitor or a FeCl3 solvent are added to regulate more electrons released from microbial respiratory metabolism to flow towards dechlorination process rather than methanogenesis process.
BEIJING INSTITUTE OF CARBON-BASED INTEGRATED CIRCUITS (China)
Inventor
Jin, Chuanhong
Wang, Bo
Ren, Xibiao
Zhang, Zhiyong
Abstract
Provided are a method for preparing a nanotube array, a nanotube array and a device. The method includes: preparing a double-layer two-dimensional material with a relative angle of lattice orientations, which is used as a template; determining the chiral parameters of nanotubes to be prepared corresponding to the relative angle of the lattice orientations of the double-layer two-dimensional material, determining a nanoribbon orientation and a nanoribbon width according to the determined chiral parameters, determining the inter-nanoribbon spacing according to the density of the nanotubes to be prepared and the nanoribbon width, and etching the double-layer two-dimensional material according to the determined nanoribbon orientation, nanoribbon width and inter-nanoribbon spacing to obtain a nanoribbon array of the double-layer two-dimensional material; and performing thermal excitation treatment on the obtained nanoribbon array of the double-layer two-dimensional material to obtain a nanotube array. The present disclosure can prepare a nanotube array with controllable density, orientation and chirality.
H10D 30/47 - FETs having zero-dimensional [0D], one-dimensional [1D] or two-dimensional [2D] charge carrier gas channels having 2D charge carrier gas channels, e.g. nanoribbon FETs or high electron mobility transistors [HEMT]
H10D 62/10 - Shapes, relative sizes or dispositions of the regions of the semiconductor bodiesShapes of the semiconductor bodies
H10D 62/17 - Semiconductor regions connected to electrodes not carrying current to be rectified, amplified or switched, e.g. channel regions
H10D 62/80 - Semiconductor bodies, or regions thereof, of devices having potential barriers characterised by the materials
A partially replaceable orthotropic steel bridge deck structure is provided, including a bridge deck laid on a top of a main girder along a longitudinal direction. The bridge deck includes a heavy-vehicle lane, a medium-vehicle lane, a light-vehicle lane and an emergency lane. A top plate structure of the bridge deck includes a first top plate and a second top plate. The heavy-vehicle lane includes a first diaphragm and the first top plate. A bottom of the first top plate is connected to a longitudinal rolled U-shaped rib arranged via a blind rivet. The medium-vehicle lane, the light-vehicle lane and the emergency lane each include a second diaphragm and the second top plate. A bottom of the second top plate is welded with a longitudinal cold-formed U-shaped rib. An erection method of such orthotropic steel bridge deck structure is also provided.
INNOVATION CENTER OF YANGTZE RIVER DELTA, ZHEJIANG UNIVERSITY (China)
ZHEJIANG UNIVERSITY (China)
Inventor
Luo, Yaozhi
Ge, Huibin
Cheng, Yuan
Yang, Chao
Abstract
A method for manufacturing a non-magnetic spatial latticed shell structure composed of carbon fiber plate members. The load-bearing member of the latticed shell structure is made of non-magnetic carbon fiber plate, and joints are made of non-magnetic titanium alloy material. The magnetic shielding layer is provided on the roofing system above the structural layer, and a non-magnetic space with a magnetic field strength lower than 1 nT is formed inside the structure. The load-bearing members are fixed by two carbon fiber limb plates in the form of inter-limb connection and forms an hollow rectangular built-up section; and the joint comprises a titanium alloy gusset plate, a titanium alloy bolt group, and a carbon fiber limb plate; the magnetic shielding layer of the roofing system comprises a shielding layer pad, a shielding layer, a shielding laminate, a buffer layer, a permalloy plate, and a batten.
METHOD, SYSTEM, COMPOSITION AND KIT FOR DIAGNOSIS AND DIFFERENTIAL DIAGNOSIS OF ALZHEIMER'S DISEASE BASED ON HUMAN BRAIN HIPPOCAMPUS SPATIAL TRANSCRIPTOMICS
THE FIRST AFFILIATED HOSPITAL, ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE (China)
Inventor
Zhang, Jing
Wang, Pan
Guo, Zhen
Xu, Zhi
Han, Lei
Pan, Danhua
Abstract
A method, system, composition and kit for diagnosis and differential diagnosis of Alzheimer's disease (AD) based on human brain hippocampus spatial transcriptomics. The present invention achieves rapid and efficient early diagnosis and differential diagnosis of AD cognitive disorder by means of one or more of CCK, Neurogranin and PMP2 carried in plasma extracellular vesicles (EVs), thereby achieving high-sensitivity and high-throughput detection of nervous system-derived EVs in peripheral blood, having the advantages of rapidness and low cost, and providing a new technical means and method for clinical application of AD cognitive disorder and large-scale screening-related accurate diagnosis work.
Provided is use of UbV.E4B protein in the preparation of a medicament for promoting central nervous regeneration. The UbV.E4B protein promotes the axonal regeneration of a central nervous system by selectively inhibiting a Ube4b ubiquitination factor. Provided is use of the Ube4b ubiquitination factor as a screening target in screening a Incdicament for promoting the axonal regeneration of the central nervous system. Further provided is a pharmaceutical composition for promoting the central nervous axonal regeneration.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 25/00 - Drugs for disorders of the nervous system
C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
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