C07C 29/149 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
C07C 209/16 - Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
C07C 29/149 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
C07C 51/41 - Preparation of salts of carboxylic acids by conversion of the acids or their salts into salts with the same carboxylic acid part
C07C 51/43 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation
C07C 51/44 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation by distillation
C07C 209/16 - Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
Processes include providing a clarified diammonium succinate (DAS)- or monoammonium succinate (MAS)- containing fermentation broth; distilling the broth of an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt% water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; and converting the solid portion to produce nitrogen containing compounds such as diamine butane (DAB), succinic dinitrile (SDN), succinic amino nitrile (SAN) or succinamide (DAM) and downstream products.
C07C 209/16 - Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
C07C 51/41 - Preparation of salts of carboxylic acids by conversion of the acids or their salts into salts with the same carboxylic acid part
C07C 51/43 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation
C07C 51/44 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation by distillation
C07C 51/02 - Preparation of carboxylic acids or their salts, halides, or anhydrides from salts of carboxylic acids
C07C 29/149 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
The present application provides genetically modified yeast cell comprising an active succinate fermentation pathway, as well as methods of using these cells to produce succinate.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12P 21/06 - Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
5.
PROCESSES FOR PRODUCING ADIPIC ACID FROM FERMENTATION BROTHS CONTAINING DIAMMONIUM ADIPATE
Processes for making AA from, either a clarified DAA-containing fermentation broth or a clarified MAA-containing fermentation broth that include distilling the broth under super atmospheric pressure at a temperature of >100°C to about 300°C to form an overhead that comprises water and ammonia, and a liquid bottoms that includes AA, and at least about 20 wt%- water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into -a liquid portion and a solid portion that is substantially.pure AA; and separating the solid portion from the liquid portion. A method also reduces the broth distillation temperature and pressure by adding an ammonia separating and/or water azeotroping solvent to the broth.
C07C 51/02 - Preparation of carboxylic acids or their salts, halides, or anhydrides from salts of carboxylic acids
C07C 51/44 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation by distillation
C07C 51/46 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation by distillation by azeotropic distillation
6.
PROCESSES FOR PRODUCING HOOC-R-COOH COMPOUND ACIDS FROM FERMENTATION BROTHS CONTAINING NH4+ -OOC-R-COQ-NH4+ COMPOUNDS
A process for making HOOC-R-COOH compound acid from a clarified NH4+ -OOC- R-COO-NH4+ compound-containing fermentation broth including distilling the broth under super atmospheric pressure at a temperature of >I00°C to about 250°C to form an overhead that comprises water and ammonia, and a liquid bottoms that Includes HOOC-R-COOH compound acid, and at least about 20 wt%. water; cooling the. bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure HOOC-R-COOH compound acid; separating the solid portion from the liquid portion; and recovering the solid portion.
Processes for making SA from either a clarified DAS-containing fermentation broth or a clarified MAS-containing fermentation broth that include distilling the broth under super atmospheric pressure at a temperature of >100°C to about 3000C to form an overhead that comprises water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt% water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion and a solid portion that is substantially pure SA; and separating the solid portion from the liquid portion. A method also reduces the broth distillation temperature and pressure by adding an ammonia separating and/or water azeotroping solvent to the broth.
patents