Medical devices for determining catheter tip location;
medical devices for monitoring and processing
electrocardiogram (ECG) signals for determining catheter tip
location; catheter tip location kits and accessories,
containing, namely, a catheter connector and ECG cable for
use in determining catheter tip location; catheter
electrodes; catheter interface modules and cables; patient
monitors for displaying catheter tip location; patient
monitors for displaying and processing electrocardiogram
(ECG) signals for determining catheter tip location;
instruments for analyzing and diagnosing cardiac and
vascular ailments.
(1) Medical devices for determining catheter tip location; medical devices for monitoring and processing electrocardiogram (ECG) signals for determining catheter tip location; catheter tip location kits and accessories, containing, namely, a catheter connector and ECG cable for use in determining catheter tip location; catheter electrodes; catheter interface modules and cables; patient monitors for displaying catheter tip location; patient monitors for displaying and processing electrocardiogram (ECG) signals for determining catheter tip location; instruments for analyzing and diagnosing cardiac and vascular ailments.
Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion are generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.
Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion are generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.
Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion are generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.
Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner. When the fluid causing the article to swell is a bodily fluid, such as a fluid the article would be exposed to upon implantation into a patient, and the article swells such that the markings have a known spacing in the patient, the markings may advantageously be employed to measure distances in the patient and/or the change in marking spacing may be employed to determine the swelling of the article in the patient.
Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion arc generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.
Medical devices, namely, stylets, cabling, electronics, and display module for determining catheter tip location; dynamic electrocardiogram (ECG) monitors for determining catheter tip location; medical devices kit for placing and securing catheters comprised of tubing for use with catheters and electrocardiogram (ECG) recorder cables for use in determining catheter tip location; medical electrodes, namely, catheter electrodes; catheter interface modules and cables; patient medical monitors for displaying catheter tip location; patient medical monitors for displaying and processing electrocardiogram (ECG) signals for determining catheter tip location; medical instruments and devices for analyzing and diagnosing cardiac and vascular ailments
10.
HIGH STRENGTH POROUS MATERIALS INCORPORATING WATER SOLUBLE POLYMERS
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.
C08L 85/02 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbonCompositions of derivatives of such polymers containing phosphorus
C08L 33/26 - Homopolymers or copolymers of acrylamide or methacrylamide
A61L 29/14 - Materials characterised by their function or physical properties
C08L 29/04 - Polyvinyl alcoholPartially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces.
A61L 29/14 - Materials characterised by their function or physical properties
A61L 29/16 - Biologically active materials, e.g. therapeutic substances
A61L 29/18 - Materials at least partially X-ray or laser opaque
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
D01F 1/08 - Addition of substances to the spinning solution or to the melt for forming hollow filaments
D01F 6/14 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated alcohols, e.g. polyvinyl alcohol, or of their acetals or ketals
D01F 6/50 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyalcohols, polyacetals or polyketals
Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner. When the fluid causing the article to swell is a bodily fluid, such as a fluid the article would be exposed to upon implantation into a patient, and the article swells such that the markings have a known spacing in the patient, the markings may advantageously be employed to measure distances in the patient and/or the change in marking spacing may be employed to determine the swelling of the article in the patient.
Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner. When the fluid causing the article to swell is a bodily fluid, such as a fluid the article would be exposed to upon implantation into a patient, and the article swells such that the markings have a known spacing in the patient, the markings may advantageously be employed to measure distances in the patient and/or the change in marking spacing may be employed to determine the swelling of the article in the patient.
Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner. When the fluid causing the article to swell is a bodily fluid, such as a fluid the article would be exposed to upon implantation into a patient, and the article swells such that the markings have a known spacing in the patient, the markings may advantageously be employed to measure distances in the patient and/or the change in marking spacing may be employed to determine the swelling of the article in the patient.
Packaging for hydrated articles are generally provided. In some embodiments, packaged articles are provided. For example, in some embodiments, a container contains an article such as a catheter and/or polymeric material. The disclosed packaged articles may be useful for, for example, providing controlled humidity conditions for contained components, maintaining consistent hydration levels of the packaged articles, and/or improved sterilization conditions. Advantageously, the packaged articles described herein may, in some embodiments, create an environment with minimum relative humidity for long-term storage of a catheter or polymeric material, increase shelf life of the catheter or polymeric material, and/or facilitate hydration of a catheter such that e.g., the catheter hydrates to intended dimensions within a specified amount of time. Methods for preparing such packaged article are also provided.
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Packaging for hydrated articles are generally provided. In some embodiments, packaged articles are provided. For example, in some embodiments, a container contains an article such as a catheter and/or polymeric material. The disclosed packaged articles may be useful for, for example, providing controlled humidity conditions for contained components, maintaining consistent hydration levels of the packaged articles, and/or improved sterilization conditions. Advantageously, the packaged articles described herein may, in some embodiments, create an environment with minimum relative humidity for long-term storage of a catheter or polymeric material, increase shelf life of the catheter or polymeric material, and/or facilitate hydration of a catheter such that e.g., the catheter hydrates to intended dimensions within a specified amount of time. Methods for preparing such packaged article are also provided.
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Packaging for hydrated articles are generally provided. In some embodiments, packaged articles are provided. For example, in some embodiments, a container contains an article such as a catheter and/or polymeric material. The disclosed packaged articles may be useful for, for example, providing controlled humidity conditions for contained components, maintaining consistent hydration levels of the packaged articles, and/or improved sterilization conditions. Advantageously, the packaged articles described herein may, in some embodiments, create an environment with minimum relative humidity for long-term storage of a catheter or polymeric material, increase shelf life of the catheter or polymeric material, and/or facilitate hydration of a catheter such that e.g., the catheter hydrates to intended dimensions within a specified amount of time. Methods for preparing such packaged article are also provided.
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Biologically active agents may be entrapped in pores of materials to provide a controlled release of the biologically active agent.
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Biologically active agents may be entrapped in pores of materials to provide a controlled release of the biologically active agent.
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Biologically active agents may be entrapped in pores of materials to provide a controlled release of the biologically active agent.
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces.
A61L 29/16 - Biologically active materials, e.g. therapeutic substances
A61L 29/18 - Materials at least partially X-ray or laser opaque
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
D01F 6/14 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated alcohols, e.g. polyvinyl alcohol, or of their acetals or ketals
D01F 6/50 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyalcohols, polyacetals or polyketals
B29K 105/04 - Condition, form or state of moulded material cellular or porous
B29C 48/86 - Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling at the nozzle zone
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.
A61L 29/14 - Materials characterised by their function or physical properties
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.
A61L 29/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
A61L 29/14 - Materials characterised by their function or physical properties
C08L 29/04 - Polyvinyl alcoholPartially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
C08L 33/10 - Homopolymers or copolymers of methacrylic acid esters
C08L 33/26 - Homopolymers or copolymers of acrylamide or methacrylamide
C08L 85/02 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbonCompositions of derivatives of such polymers containing phosphorus
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces.
A61L 29/16 - Biologically active materials, e.g. therapeutic substances
A61L 29/18 - Materials at least partially X-ray or laser opaque
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
B29C 67/00 - Shaping techniques not covered by groups , or
B29K 105/04 - Condition, form or state of moulded material cellular or porous
D01F 6/14 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated alcohols, e.g. polyvinyl alcohol, or of their acetals or ketals
D01F 6/50 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyalcohols, polyacetals or polyketals
B29C 48/86 - Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling at the nozzle zone
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces.
A61L 29/14 - Materials characterised by their function or physical properties
B29C 47/00 - Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor (extrusion blow-moulding B29C 49/04)
B29C 47/78 - Heating or cooling the material to be extruded or the stream of extruded material
A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
D01D 5/24 - Formation of filaments, threads, or the like with a hollow structureSpinnerette packs therefor
D01F 6/14 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated alcohols, e.g. polyvinyl alcohol, or of their acetals or ketals
A61L 17/10 - At least partly resorbable materials containing macromolecular materials
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces.
A61L 29/16 - Biologically active materials, e.g. therapeutic substances
A61L 29/18 - Materials at least partially X-ray or laser opaque
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
B29C 67/00 - Shaping techniques not covered by groups , or
B29K 105/04 - Condition, form or state of moulded material cellular or porous
D01F 6/14 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated alcohols, e.g. polyvinyl alcohol, or of their acetals or ketals
D01F 6/50 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyalcohols, polyacetals or polyketals
B29C 48/86 - Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling at the nozzle zone