Provided is an ion analyzer for analyzing an ion using radical-induced dissociation. A generator (21, 210) generates a radical from a source gas. A gas supplier (26, 3) supplies a gas mixture as the source gas to the generator during an analysis. The gas mixture is prepared by mixing a first gas which is a source for a radical having oxidizing power or which itself has oxidizing power, and a second gas which is a source for a radical having reducing power or which itself has reducing power, at a predetermined ratio specified so that the efficiency of dissociation by the radical originating from the first gas is not lower than that when the second gas is not mixed. A radical generated by the generator is introduced into a reaction chamber (132), within which an ion originating from a sample is dissociated by coming in contact with the radical.
G01N 27/68 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using electric discharge to ionise a gas
This liquid collection and injection device for collecting a liquid and injecting the liquid into a predetermined place includes: a tubular tip (153) for suctioning and discharging the liquid in a state in which the leading end of the tip is directed downward; movement mechanisms (160, 181, 182) for moving the tip in a three-dimensional space; an imaging unit (155) for imaging the leading end of the tip; a photoelectric sensor (170) having a light projection unit (171) and a light reception unit (172); and a position specifying unit (123) for specifying a position in the three-dimensional space of the leading end of the tip on the basis of an image of the leading end of the tip imaged by the imaging unit and detection information obtained by detecting the leading end of the tip by means of the photoelectric sensor.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
SHIMADZU CORPORATION (Japan)
Inventor
Andrzejewski, Roch
Abstract
A fluorescence lifetime imaging device for imaging the fluorescent output of a target fluorophore at an imaged subject spaced from the imaging device by a spacing. The imaging device comprises a light source configured to emit excitation light for fluorescent excitation of the target fluorophore. A first optical sensor is configured to detect returned excitation light scattered from the imaged subject, and a second optical sensor is configured to detect fluorescent light emitted by the fluorophore in response to excitation thereof by the excitation light, and to output a corresponding fluorescence intensity detection output. An image data generating unit is configured to generate data describing fluorescence lifetime images based on said fluorescence intensity detection output according to a time of occurrence of said detection of returned excitation light corresponding to a time-of-flight of excitation light across said spacing between the light source and the imaged subject.
A treatment support apparatus (100) includes an excitation light source (21) configured to irradiate a fluorescent substance (301) of a drug (300) administered into a cancer patient's (200) body with excitation light in a specific waveband having energy that excites the fluorescent substance (301) but does not kill a cancer cell (301) before or after treatment to kill the cancer cell (201) based on irradiating the drug (300) containing the fluorescent substance (301) with light in a specific waveband, a fluorescence detector (26) configured to detect fluorescence emitted by the fluorescent substance (301) of the drug (300) due to excitation by the excitation light, and an image generator (16) configured to generate a fluorescence distribution image (41), which is an image showing a distribution state of the fluorescence emitted by the fluorescent substance (301), based on the fluorescence from the fluorescent substance (301) detected by the fluorescence detector (26).
A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A preparative chromatograph system includes: a chromatograph part including a separation column and a detector; a fraction collector for executing a fractionation collecting operation of dropping and collecting the eluate flowed out from the separation column through a nozzle into a plurality of collection containers; a controller configured to control an operation of the fraction collector based on a preset fractionation collecting condition; an information processing device configured to perform information processing relating to the fractionation collecting operation; and a display. The information processing device is configured to output a chromatogram created based on a signal of the detector to the display in a state where fractionated sections on the chromatogram collected in the plurality of collection containers by the fraction collector and collection information including a collection purpose for which each fractionation section has been collected are added to the chromatogram.
An atomic absorption spectrophotometer (1), including: a sample collection unit (24) to which a chip (25) configured to collect and eject a sample is attached; a sample heating unit (11) configured to excite the sample, provided with an opening (14) in an upper face into which the sample is injected from the sample collection unit (24); a moving mechanism (27) configured to move the sample collection unit between a first position for collecting the sample into the chip and a second position for injecting the sample from the chip to the opening; a light irradiating unit (29) configured to irradiate a light on the opening from a predetermined lighting direction; and an image acquisition unit (26) configured to image the opening from an optical axis direction different from the lighting direction.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/74 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light thermally excited using flameless atomising, e.g. graphite furnaces
A preparative chromatograph system (1) includes a fractionation collecting condition correction part (18) configured to detect a change in a chromatogram acquired in each of a plurality of injections of a sample during stack injection fractionation collecting and to correct a fractionation collecting condition during the stack injection fractionation collecting so that the chromatogram approaches a state before the change, wherein the stack injection fractionation collecting continues based on the corrected fractionation collecting condition after the fractionation collecting condition correction part (18) has corrected the fractionation collecting condition.
B01D 15/24 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
B01D 15/14 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
8.
SCANNING PROBE MICROSCOPE, CONTROL DEVICE, CONTROL PROGRAM, AND CONTROL METHOD
This scanning probe microscope (100) for subjecting the surface of a sample (S) to analytical processing comprises: a cantilever (101); a detecting device (12) for detecting a physical characteristic of the cantilever (101); and a control device (11) for identifying the spring constant of the cantilever (101) on the basis of the physical characteristic detected by the detecting device (12). The control device (11) stores specific information (Tb1) for identifying the spring constant on the basis of the physical characteristic, acquires the physical characteristic detected by the detecting device (12), and identifies the spring constant on the basis of the acquired physical characteristic and the specific information (Tb1).
The present disclosure relates to: a proportional counter (10) comprising a container (11) and a core wire (12) disposed within the container (11), wherein a gas is sealed within the container (11), the container (11) is provided with an entrance window (13), and a graphene sheet (14) is disposed in the entrance window (13); and a wavelength dispersive fluorescent x-ray analysis device (20, 40). The present disclosure provides the gas-filled proportional counter (10) that can be used for fluorescent X-ray analysis of ultra-light elements, and the wavelength dispersive fluorescent x-ray analysis device (20, 40) including the gas-filled proportional counter.
G01T 1/18 - Measuring radiation intensity with counting-tube arrangements, e.g. with Geiger counters
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01N 23/2209 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using wavelength dispersive spectroscopy [WDS]
A stress light emission measurement device (100) comprises an excitation light source (50), an imaging device (60), optical filters (F1, F2), and a processing device (70). The excitation light source (50) is configured to irradiate a stress light-emitting body (90) with excitation light before and during application of external force to the stress light-emitting body. The imaging device (60) images light emitted by the stress light-emitting body (90). The optical filters (F1, F2) remove an excitation light component from the captured image. The processing device (70) calculates, on the basis of the captured image produced by the imaging device (60), a stress light emission image that indicates stress light emission when external force is applied to the stress light-emitting body (90).
G01N 21/70 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light mechanically excited, e.g. triboluminescence
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
Andrzejewski, Roch
Knight, Patrick
Shvartsburg, Alexandre A.
Abstract
VDD EDD D , across the analytical gap containing the flow of gas. The drift region is irradiated with light from a light source thereby to irradiate the ions entrained within the flow of gas contained therein such that the entrained ions are subject to the dispersion electric field and the light from the light source.
Provided is a method for analyzing a neurogranin-related peptide by matrix assisted laser desorption/ionization-mass spectrometry, in which a laser irradiation target contains the neurogranin-related peptide, a matrix, and a protein of 9 kDa or more, and a content of the protein per 1 μg of the matrix is 10 fmol or more and 600 fmol or less.
Provided is a technique for providing objective and highly accurate information for taste evaluation. A device acquires information about respective amounts of two or more types of components in a target (step S21). The two or more types of components are associated with a specific taste. The device derives a determination result as to whether the target has the specific taste, based on ratio information about a ratio of each of the two or more types of components and information about an amount of each of the two or more types of components (step S23), and outputs the determination result (step S24).
A time-of-flight mass spectrometer (100) is provided with: an ejection unit (27) that ejects ions for each sequence; a flight tube (32); an ion detector (35); and a signal processing device (7) that generates a mass spectrum on the basis of detection values from the ion detector and outputs a display signal for displaying the mass spectrum. The signal processing device generates one-shot data for each sequence using the detection values and, after correcting the one-shot data, generates the mass spectrum through a process (S10) of integrating the corrected one-shot data. The correction includes shift correction that shifts the one-shot data in the flight time axis direction.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
15.
Method of Quantifying Antigen-Binding Molecule Bound to Cells
Provided is a method of quantifying an antigen-binding molecule bound to cells, comprising: a preparation step of preparing a biological sample derived from the cells, wherein the biological sample is homogenized, the cells express a target antigen bound specifically to the antigen-binding molecule, and the cells have been exposed to the antigen-binding molecule; an extraction step of adding an extraction solution to the biological sample to obtain an analyte, wherein the extraction solution comprises an organic acid and a nonionic surfactant, and the extraction solution has a pH of 1 or more and 3 or less; and a quantification step of analyzing the analyte to quantify the antigen-binding molecule.
This experimental system comprises: an experimental device capable of simultaneously executing a plurality of experiments with dissimilar experimental conditions; and a search device for searching for experimental conditions to be used in the experimental device. The search device sets a first experimental condition using a first experiment planning method, controls the experimental device so that the experimental device executes a first experiment based on the first experimental condition, and sets a second experimental condition using a second experiment planning method on the basis of the result of the first experiment. Each of the first experiment planning method and the second experiment planning method includes a Bayesian optimization method using a first acquisition function, and a Bayesian optimization method using a second acquisition function different from the first acquisition function.
A cell cultivation apparatus (100) according to this invention includes a device holder (101), and gas pipes (31) for supplying a gas to cultivation chambers (23). The device holder includes a holder-side lid (10) including an attachment (30) for the gas pipes and holder-side ports (11). The holder-side lid is movable between a connection position and a disconnection position, the connection position being a position in which the gas pipes and the holder-side ports are connected to device-side ports (21) of a device-side lid (25) of a cell cultivation device (20), the disconnection position being a position in which the connection is released.
In this X-ray imaging device (100), a control unit (10) generates a plurality of selection X-ray images (A1-A7, B1-B7, C1-C7, and D1-D7) having different viewing characteristics corresponding to a plurality of selection parameters extracted from a storage unit (7), sets a selection parameter used for the generation of a selected one selection X-ray image (D5) as an observation parameter (P1) for generating an observation X-ray image (I1), and stores the selection parameter in the storage unit (7).
A mass spectrometry device (10) comprises: an ion generation mechanism; an ion trap mechanism (140); a detector (150); and a voltage generation circuit (180). The ion trap mechanism captures ions in an internal space surrounded by a plurality of electrodes. The detector detects ions that have been discharged from the ion trap mechanism. The plurality of electrodes include: first electrodes (141) that generate an electric field for capturing ions; and second electrodes (142, 144) that, while the ions are being captured, generate an electric field for discharging specific ions from the ion trap mechanism. The voltage generation circuit includes: voltage sources (181, 182); switches (SW1, SW2); and resistance circuits (RC1, RC2). The voltage source (182) supplies a lower voltage than the voltage source (181). The switches (SW1, SW2) selectively supply the voltages from the voltage sources (181, 182) to the first electrode. The resistance circuits (RC1, RC2) are respectively connected to control terminals of the switches (SW1, SW2). Each of the resistance circuits has a variable resistance value.
G01N 30/26 - Conditioning of the fluid carrierFlow patterns
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
This device comprises: an X-ray tube 11; an X-ray detector 9; an X-ray image generation unit 51; and an optical image capturing unit 29 arranged in an inspection room R1. The optical image capturing unit 29 includes: a housing 33; an opening 35 arranged on the housing 33; an optical lens 37 of a photographic camera 36 arranged inside the housing 33 so as to face the opening 35; and a shielding member 41 configured to be movable between a shielding position P1 and a retreat position P2 inside the housing 33 and capable of shielding the optical lens 37. The shielding member 41 is configured to shield the optical lens 37 so that the optical lens 37 cannot be visually recognized from the outside of the opening 35 in a state where the shielding member 41 is moved to the shielding position P1, and to enable the photographic camera 36 to capture an optical image through the opening 35 in a state where the shielding member 41 is moved to the retreat position P2.
This X-ray imaging system (100) is provided with: an X-ray irradiation unit (10); an X-ray detection unit (20) that detects X-rays; an optical imaging unit (31) that captures an image of an optical image (70) of a subject (101); a display unit (41); and a control unit (32) configured to cause a position reference image (90), which is disposed inside the X-ray detection unit (20) and indicates the position relative to the center of the X-ray detection unit (20), to be superimposed on the optical image (70) and displayed on the display unit (41).
This X-ray imaging device (100) is provided with: an optical imaging unit (31) for imaging an optical image (70); and an optical imaging control unit (32). The optical imaging control unit is configured to perform control for switching from a first mode to a second mode. The first mode is for displaying, with reference to a prescribed fixed position in a real space: an optical image on which is superimposed a region display (80) which includes at least one of a detection unit region display (81), an X-ray irradiation field region display (84), and an X-ray lighting field region display (87); or an optical image on which a region display is not superimposed. The second mode is for displaying an optical image on which is superimposed a region display that references a position on a body surface (101a) of a subject (101) in a real space.
This X-ray imaging device (100) comprises an optical imaging unit (30) and a control unit (32) that generates an enlarged partial image (3). The control unit (32) is configured such that, on the basis of the relationship between the optical axis (5) of the optical imaging unit (30) and an emission axis (6) of X-rays, the center position (3a) of the enlarged partial image (3) is shifted from the center position (2a) of an optical image (2) toward the position, in a real space, of the intersection (4) between an X-ray detection unit (20) and the emission axis (6) of X-rays emitted from an X-ray emission unit (10).
This X-ray imaging device (100) comprises a control unit (32) that calculates the distance (D1) between an X-ray tube (11) and a subject (101) on the basis of the coordinates of a prescribed position (33c) in an irradiation field region (33a) captured on the body surface of the subject (101) in an optical image (70) that is captured by an optical imaging unit (31).
A power supply that applies a tube voltage to a target includes a transformer, a switching circuit connected to a primary side of the transformer, and a substrate to which the switching circuit and the transformer are connected, the substrate including a first layer and a second layer. The transformer includes a first primary winding and a second primary winding on the primary side. A first wiring pattern that connects the first primary winding and the switching circuit to each other is located in the first layer. A second wiring pattern that connects the second primary winding and the switching circuit to each other is located in the second layer. The first layer and the second layer are arranged such that at least a part of the first wiring pattern overlaps with the second wiring pattern when the substrate is viewed from a stacked direction in a plan view.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
H01F 30/06 - Fixed transformers not covered by group characterised by the structure
H05G 1/10 - Power supply arrangements for feeding the X-ray tube
27.
METHOD FOR DETERMINING CHEMICAL STRUCTURE OF LIPID AND ION MOBILITY-TANDEM MASS SPECTROMETER
The present disclosure relates to the field of mass spectrometry, and particularly provides a method for determining a chemical structure of a lipid and an ion mobility-tandem mass spectrometer. The method for determining a chemical structure of a lipid includes: an ionization step of ionizing a sample to obtain sample ions; an ion mobility-based separation step of separating target lipid ions from the sample ions based on ion mobility; a first dissociation step of dissociating the target lipid ions with dissociation energy adjusted to break a first chemical bond of the target lipid ions; a mass-based selection step of selecting the target lipid ions, whose first chemical bond is broken, based on a mass number to obtain fragment ions; a second dissociation step of dissociating the fragment ions to at least break a second chemical bond of the fragment ions which has bond energy higher than the first chemical bond, to obtain diagnostic ions; and a mass analysis step of performing a mass analysis on the diagnostic ions.
A mass spectrometer includes a mass filter, a wave-detection unit and a power supply device. The mass filter selects ions having a mass-to-charge ratio corresponding to an applied AC voltage. The wave-detection unit detects an AC voltage to be applied to the mass filter. The power supply device applies an AC voltage to the mass filter based on an AC voltage detected by the wave-detection unit. The wave-detection unit has a plurality of rectifiers. Each of the plurality of rectifiers includes a rectifying device. The plurality of rectifiers are electrically connected to one another in parallel.
An X-ray fluorescence spectrometer includes a first power supply that applies a tube voltage and a second power supply that supplies a filament current. The first power supply includes a switching circuit connected to a primary side of a transformer. The X-ray fluorescence spectrometer includes a current detection circuit connected to the primary side of the transformer to detect a current that flows to the primary side of the transformer and a control circuit that controls the first power supply based on the detected current. The current detection circuit includes a first comparator configured to detect whether or not the current detected by the current detection circuit is equal to or larger than a first threshold value. The control circuit detects occurrence of electric discharge based on detection of the current equal to or larger than the first threshold value by the current detection circuit.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01R 19/165 - Indicating that current or voltage is either above or below a predetermined value or within or outside a predetermined range of values
A gas analysis system (1) includes a first flow channel (L1) through which sample gas that has passed through a column (41, 42) over helium gas as carrier gas flows, a second flow channel (L2) through which sample gas that has passed through a column (43, 44) over nitrogen gas as carrier gas flows, a TCD (90) that detects components in gas by making use of a difference in thermal conductivity among the components, and a switching module (M3). The switching module (M3) is arranged among the first flow channel (L1), the second flow channel (L2), and the TCD (90), and configured to switch between a first state in which the TCD (90) is connected to the first flow channel (L1) and a second state in which the TCD (90) is connected to the second flow channel (L2).
B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography
B01D 53/30 - Controlling by gas-analysis apparatus
A data processing method according to the present disclosure sets based on a first collection condition associated with a first separation condition, a second collection condition associated with a second separation condition. The data processing method according to the present disclosure includes calculating predicted retention time of each target component under the second separation condition, setting timings to start and quit collection of data under the second collection condition, and causing a chromatograph mass spectrometer to separate a sample under the second separation condition and to collect data on the target component under the second collection condition.
The control device (100) controls the deflection amount (D2), which is the pressing amount, to a deflection amount (D1), which is a target value (DT), based on the set value (DS1, DS2) of the pressing amount when pressing the cantilever (12) against the sample (S) when measuring the force curve, and changing the set value (DS1) to the set value (DS2) based on the deflection amount (D3), which is differential data indicating the difference between the deflection amount (D1), which is the target value (DT), and the deflection amount (D), which is the actual pressing amount, in a previously performed force curve measurement when measuring the force curve.
A gas analysis system (1) includes an inflow portion (C1) into which sample gas flows, a column (41, 42), a detector (50, 51) that detects a component in sample gas, a sampler module (M1) and a switching module (M2) including a plurality of valves (V1 to V10), and a controller (100) that independently controls the plurality of valves (V1 to V10). The controller (100) includes a storage (120) where function pattern information that defines correspondence between a plurality of basic functions and opening and closing patterns of the plurality of valves is stored and an output unit (110) that uses the function pattern information stored in the storage (120) to output control signals to the respective valves (V1 to V10).
This tube supporting plate includes a plate and a cover. The plate holds microtubes in a state in which a lid is not attached to an upper opening of a container body. The cover has formed therein through-holes corresponding to the container body, and the cover is disposed above a seal.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
This X-ray imaging device (100) is provided with: a holding unit (40) that holds an X-ray irradiation unit (10) so that the same can be moved in the horizontal direction; an optical imaging unit (30) that is provided to the holding unit (40); and a display unit (41) that is provided to the holding unit (40). The X-ray imaging device is configured so that a first display state of an optical image (2) displayed on the display unit (41) can be switched to a second display state in which the orientation of a subject (1) is rotated so as to match the orientation of the subject (1) in an X-ray image.
A method of measuring biological information according to the present disclosure is a measurement method of measuring biological information from a frame image group obtained by imaging over time of a subject. The method of measuring biological information according to the present disclosure divides a target region in each frame image included in the frame image group into a plurality of sub regions and extracts an amount of variation in each of the plurality of sub regions from the frame image group. The method of measuring biological information then determines sub regions similar in amount of variation from among the plurality of sub regions and obtains the biological information of the subject based on a summed value of the amount of variation in each of the similar sub regions.
The present disclosure relates to the field of mass spectrometry, and specifically to a method for identifying an unsaturated organic compound and a mass spectrometry system, which are particularly suitable for implementing position identification of a carbon-carbon double bond of an unsaturated lipid. The identification method includes a derivatization reaction step of aziridinating a carbon-carbon double bond in the unsaturated organic compound by an aza-Prilezhaev reaction to obtain a derivatization product, and then specifically dissociating the derivatization product, and performing mass analysis. Compared with the existing method, the identification method has at least one of the advantages of mild reaction conditions, minimal over-derivatization, minimal side reactions, and high conversion rate.
X-ray CT apparatus including an X-ray generation device and an X-ray detector that detects an X-ray emitted from the X-ray generation device and passing through an inspection object, and collecting X-ray projection data of at least two types of X-ray energies to reconstruct a dual energy image, the X-ray CT apparatus further includes: an acquisition unit that acquires inspection object information including a physical quantity and physical property information of the inspection object, and X-ray characteristic information of an X-ray spectrum, an X-ray filter, and the X-ray detector; and an X-ray imaging condition determination unit that determines X-ray imaging conditions for collecting X-ray projection data of the at least two types of X-ray energies emitted from the X-ray generation device, on the basis of the inspection object information and the X-ray characteristic information of the X-ray spectrum, the X-ray filter, and the X-ray detector acquired by the acquisition unit.
The objective of the present invention is to reduce the influence of disturbances acting on electromagnetic waves emitted toward an object. A measuring device (100) comprises a transmitting and receiving unit (11) and an information processing unit (15). The transmitting and receiving unit (11) emits primary electromagnetic waves toward a measurement target object (SA) and receives secondary electromagnetic waves returning from the measurement target object (SA). The information processing unit (15) calculates the moisture content of the measurement target object (SA) on the basis of the primary electromagnetic waves and the secondary electromagnetic waves.
G01N 22/00 - Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
This optical measuring device comprises a light source, an ultrasound wave source, a detector, a control device, and an analysis device. The control device acquires a first speckle image and a second speckle image on the basis of outputs of a detector acquired in a first imaging period and a second imaging period, causes laser light to be emitted in the first imaging period and the second imaging period, and causes oscillation of ultrasound waves from the ultrasound wave source such that the ultrasound waves reach a measuring position. The analysis device calculates a first variation component indicating an amount of variation of speckle in a first region and a second variation component indicating an amount of variation of speckle in a second region between the first speckle image and the second speckle image, and extracts a modulated signal component from the first variation component and the second variation component.
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 29/06 - Visualisation of the interior, e.g. acoustic microscopy
This optical measurement device comprises a light source, an ultrasonic wave source, an imaging device, a control device, and an analysis device. The control device causes the imaging device to image, during first to third imaging periods, signals of laser light that has passed through a region in a light scattering body, and controls imaging timings such that the interval between the first imaging period and the second imaging period and the interval between the second imaging period and the third imaging period are equal. The control device causes first laser light, second laser light, and third laser light to be respectively emitted from the light source during the first imaging period, the second imaging period, and the third imaging period, and causes ultrasonic waves to be generated from the ultrasonic wave source at the emission timing of the third laser light such that the ultrasonic waves arrive at a measurement location. The analysis device extracts modulated signal components by using a signal of the first laser light, a signal of the second laser light, and a signal of the third laser light, which have passed through the region in the light scattering body.
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 29/06 - Visualisation of the interior, e.g. acoustic microscopy
An object of the present invention is to provide a mass spectrometer capable of easily attaching and detaching electrical wiring of an ion optical element even when another system unit or the like is placed on an upper part of the mass spectrometer.
An object of the present invention is to provide a mass spectrometer capable of easily attaching and detaching electrical wiring of an ion optical element even when another system unit or the like is placed on an upper part of the mass spectrometer.
A mass spectrometer comprises: a chamber VC forming a vacuum chamber; an ion optical element MFP arranged in the chamber; and a power supply line for supplying power to the ion optical element from a power source arranged outside the chamber. An opening OP is formed in at least a portion of wall surfaces of the chamber, excluding upper and lower surfaces and a side lid VC1 is provided to cover the opening. A connecting position between the power supply line FT and a cable CA and a connecting position between the ion optical element (terminal MT) and the cable CA are set at positions that allow the cable CA to be removed from the opening with the ion optical element housed in the chamber.
A photoelectric conversion device includes an amplifier, a photodetector, a first resistor, a second resistor, a first switch, a first terminal, a second terminal, a second switch, a third switch, and a controller. In setting a gain of the amplifier to a second gain, the controller is configured to control the first switch and the third switch to a conducting state and control the second switch to a non-conducting state. In setting the gain of the amplifier to a first gain, the controller is configured to control the first switch and the third switch to the non-conducting state and control the second switch to the conducting state so as to set a potential at one end and a potential at the other end to be equal in the first switch.
This X-ray imaging device (100) comprises: an imaging table (1); an X-ray irradiation unit (2) that irradiates a subject (200) with X-rays; an X-ray detection unit (3) that detects the X-rays emitted by the X-ray irradiation unit; a movement mechanism (4) that supports the X-ray irradiation unit so as to be capable of moving at least in the vertical direction; a display unit (51) provided to the X-ray irradiation unit; a display unit holding part (52) that holds the display unit on a front surface (521) side; a first handle (53) provided to the display unit holding part and gripped by an operator (201) when moving the X-ray irradiation unit via the movement mechanism; and a second handle (54) which is provided below the first handle and on a rear surface (522) of the display unit holding part, and which is gripped by the operator when moving the X-ray irradiation unit via the movement mechanism.
An X-ray fluoroscopic imaging device (100) comprises a control unit (6) that performs control for causing irradiation of X-rays by an X-ray irradiation unit (21) on the basis of an input operation of an operation unit (3), and performs control for generating an X-ray image. The control unit (6) is configured such that when the pixel value of a pixel included in the generated X-ray image is included in the range of a target pixel value (58), the X-ray irradiation by the X-ray irradiation unit (21) is stopped even when reception of the input operation for causing irradiation of X-rays is continued by the operation unit (3).
The present invention involves: dividing target elements including Cd, Pb, As, Hg, Co, V, and Ni into a plurality of groups so that As and Pb belong to the same group and are separated from a group Hg belongs to; and adding, for each group, a liquid (12, 121 to 128) containing target elements belonging to the group to powder (11) made of a material not containing any of the target elements and mixing the liquid with the powder so that the target elements belonging to the group each reach a predetermined concentration.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01N 1/00 - SamplingPreparing specimens for investigation
47.
METHOD, PROGRAM, AND ENERGY-DISPERSIVE FLUORESCENT X-RAY ANALYSIS SYSTEM
This method comprises: a step for acquiring, from a memory in which an analysis range and a background energy range corresponding to each of one or more elements are stored, an analysis range that corresponds to a given target element and a background energy range that corresponds to the target element in order to create a calibration curve for the target element; a step for deriving, for each of one or more standard samples containing the target element at different concentrations, the ratio of the X-ray intensity of the analysis range that corresponds to the target element and the X-ray intensity of the background energy range that corresponds to the target element; and a step for creating a calibration curve for the target element by using the ratios for each of the one or more standard samples.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
Provided is a technique for the highly sensitive quantification of As in a target sample in which Pb may be admixed. Provided is a method for determining the arsenic content in a target sample in which lead may be admixed, wherein this method uses: the intensity of the Kα line for arsenic in the spectrum of a target sample measured by using energy-dispersive X-ray fluorescence analysis; a first calibration curve for arsenic; and a first correction coefficient for correcting the arsenic-related overlap with lead. The first calibration curve and first correction coefficient in this method are obtained by using a plurality of standard samples that include a first standard sample that does not contain arsenic.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
The present invention comprises: a gas chromatograph 1 having a separation column 10 for separating a plurality of components contained in a gas to be analyzed; a timing detection unit 2 for detecting a timing at which each of the plurality of components exits the separation column; a gas recovery unit 5 for recovering, to a sample bag, a component gas containing all or a portion of the plurality of components exiting the separation column; a gas introduction unit 56 for introducing a dilution gas into the sample bag under a prescribed gas introduction condition; a flow rate information acquisition unit 14 for acquiring flow rate information of the component gas; a time range setting unit 63, 65, 66 for setting, upon referring to the timing, a time range in which the gas recovery unit recovers the component gas; a total volume setting unit 63, 65, 66 for setting the total volume of the component gas recovered in the sample bag and the dilution gas introduced into the sample bag; and a condition determination unit 62 for determining the gas introduction condition on the basis of the flow rate information, the time range, and the total volume.
A lock mechanism (300) includes a lever (301) and an engaging portion (302). The lever (301) is provided in a main body (100) or an ion source (200), and is rotatable between a locked state in which the ion source (200) is maintained in a closed state with respect to the main body (100) and an unlocked state in which the ion source (200) is openable with respect to the main body (100). The engaging portion (302) includes a first engaging member (321) and a second engaging member (322) at least one of which is rotatably provided, and the first engaging member (321) and the second engaging member (322) are engaged with each other in the locked state. At least one of the first engaging member (321) and the second engaging member (322) rotates while being in contact with each other as the lever (301) rotates from the unlocked state to the locked state.
A nucleic acid structural analysis method includes: an HAD-MSn analysis step (101) of introducing a hydrogen radical into a space in which an ion derived from a test nucleic acid is present to perform dissociation of the ion, and performing mass spectrometry on a plurality of fragment ions generated by the dissociation to collect m/z information on the plurality of fragment ions; and a structure estimation step (103) of estimating a structure of the test nucleic acid on a basis of the m/z information on the plurality of fragment ions obtained in the HAD-MSn analysis step. This makes it possible to deal with precursor ions having various charges, and makes it easier to perform the structure estimation of the nucleic acid based on the mass spectrum.
An image processing method according to the present disclosure includes a step (S10) for acquiring first image data obtained by measuring a first sample according to a first measurement method and a step (S12) for setting a first region-of-interest candidate group on the basis of the first image data. The image processing method further comprises: a step (S14) for acquiring second image data reflecting a physical quantity different from that of the first image data, the second image data being obtained by measuring the first sample according to a second measurement method different from the first measurement method; and a step (S16) for setting a region-of-interest group with respect to the first image data or the second image data on the basis of the first region-of-interest candidate group and the second image data.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
53.
UNDERWATER OPTICAL COMMUNICATION SYSTEM AND UNDERWATER OPTICAL COMMUNICATION METHOD
An underwater optical communication system 1 according to this invention includes a first optical communication device 10 arranged underwater; a second optical communication device 20 being provided to a moving body 3 for moving underwater, and performing bidirectional optical communication between the second optical communication device and the first optical communication device 10; and a control device 30 for presenting at least one of a recommended relative position 41 and an unrecommended relative position 42 of at least the second optical communication device 20 relative to the first optical communication device 10 in the optical communication based on disturbance light.
H04B 10/80 - Optical aspects relating to the use of optical transmission for specific applications, not provided for in groups , e.g. optical power feeding or optical transmission through water
G01C 13/00 - Surveying specially adapted to open water, e.g. sea, lake, river or canal
G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
H04B 10/079 - Arrangements for monitoring or testing transmission systemsArrangements for fault measurement of transmission systems using an in-service signal using measurements of the data signal
A testing device (100) comprises: a testing unit (100A) for performing a test; and a disposal unit (100B) for recovering waste discharged from the testing unit (100A). The disposal unit (100B) comprises a container (3) that accommodates waste and has an inner surface formed of a material that does not react with chemicals; a bottom surface member (5) that constitutes the bottom surface of the container (3); and an attachment/detachment mechanism that discharges the waste accommodated in the container (3) by attaching and detaching the bottom surface member (5) to and from the container (3).
B65F 1/12 - Refuse receptacles with devices facilitating emptying
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 37/00 - Details not covered by any other group of this subclass
55.
Display screen or portion thereof with transitional graphical user interface
Provided is a method of analyzing a biomolecule present at a vesicle, the method comprising: bringing a vesicle into contact with a capturing molecule solidified on a support; bringing a first detection molecule labeled with a first metal particle into contact with the vesicle; bringing a second detection molecule labeled with a second metal particle into contact with the vesicle; and quantifying the first metal particle and the second metal particle bonded to the vesicle by inductively coupled plasma (ICP) mass spectrometry or ICP emission spectroscopy.
G01N 27/68 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using electric discharge to ionise a gas
58.
IMAGING ANALYSIS DEVICE AND IMAGING ANALYSIS METHOD
An imaging analysis device according to an aspect of the present invention comprises: a measurement unit (1) that performs prescribed analysis for each of a plurality of micro-areas set within a measurement area on a target sample; analysis units (22, 23, 24, 25) that perform cluster analysis to classify the plurality of micro-areas within the measurement area into a plurality of clusters under a set cluster analysis condition, said cluster analysis being based on data for each micro-area obtained by the measurement unit; an image creation unit (27) that creates a segmentation image corresponding to the measurement area on the basis of a result of the cluster analysis; and a display processing unit (28) that arranges and displays, on the same screen of a display unit (4), a plurality of segmentation images obtained by the analysis units and the image creation unit under mutually different cluster analysis conditions for one target sample.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/00 - Particle spectrometers or separator tubes
G06F 18/23213 - Non-hierarchical techniques using statistics or function optimisation, e.g. modelling of probability density functions with fixed number of clusters, e.g. K-means clustering
59.
STANDARD SAMPLE PREPARATION METHOD, STANDARD SAMPLE, AND MIXED LIQUID
Provided is a technique for reducing the burden on a worker in the creation of a calibration curve of a plurality of types of impurity elements defined in guidelines for the management of elemental impurities in a pharmaceutical formulation, as published by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use. Energy dispersive X-ray fluorescence analysis apparatus is used to prepare standard samples for creating a calibration curve for each of two or more elements. The two or more elements are included in the impurity elements specified in the guidelines for the management of elemental impurities in pharmaceutical formulations, as defined by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use, and are stable even when present together in the same solution. The standard sample may include two or more elements.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01N 1/00 - SamplingPreparing specimens for investigation
Provided is a heat treatment furnace 100 capable of immediately generating superheated steam in a furnace body 1 without the provision of any special structure in the furnace body 1, and furthermore capable of heating a workpiece W as uniformly as possible. For this purpose, the heat treatment furnace 100 is provided with: a furnace body 1 in which a workpiece W is accommodated; a heater 4 that maintains the temperature in the furnace body 1 above 100 degrees; and a superheated steam generation mechanism 7 that generates superheated steam for heat-treating the workpiece W in the furnace body 1. The superheated steam generation mechanism 7 is provided with: a water supply pipe 71 that extends from the outside of the furnace body 1 to the inside thereof; and a spray nozzle 72 that is disposed in the furnace body 1 and jets water supplied from the water supply pipe 71.
F27D 7/02 - Supplying steam, vapour, gases or liquids
F27B 5/04 - Muffle furnacesRetort furnacesOther furnaces in which the charge is held completely isolated adapted for treating the charge in vacuum or special atmosphere
F27B 5/16 - Arrangements of air or gas supply devices
61.
ANALYSIS ABNORMALITY DIAGNOSIS SYSTEM AND ANALYSIS ABNORMALITY DIAGNOSIS METHOD
The present invention comprises: a learning model retention unit (8) that retains a plurality of parameters of analysis data acquired by normal analysis, and that retains a learning model created using learning model creation data that includes the plurality of parameters for each of a plurality of sets of analysis data acquired by analysis in a state in which a plurality of types of abnormalities are present singly or in combination, the learning model having learned, in a directional manner, the influence of the plurality of types of abnormalities on the plurality of parameters; an analysis data retention unit (10) that retains standard analysis data that is the analysis data acquired by normal analysis of a standard sample that includes a specific constituent under specific analysis conditions, and analysis data to be diagnosed acquired by analysis of a sample that includes at least the specific constituent under the specific analysis conditions; and an abnormality inference unit (12) that applies the plurality of parameters of the standard analysis data and the analysis data to be diagnosed retained by the analysis data retention unit to the learning model retained by the learning model retention unit and infers which types of abnormalities were present during the analysis that was executed in order to acquire the analysis data to be diagnosed.
Disclosed is a data processing method for processing a spectrum for a target sample obtained at an energy-dispersive x-ray fluorescence analysis device. The data processing method includes a step for reading out a correction ratio that is the ratio of a detection intensity for a second energy range to a detection intensity for a first energy range for a standard sample of Fe. The first energy range includes the energy of Kβ rays from Fe and the energy of Kα rays from Co, and the second energy range includes the energy of Kα rays from Fe. The data processing method also includes a step for calculating the product of the correction ratio and a detection intensity for the second energy range of the spectrum as a correction value and a step for subtracting the correction value from a detection intensity for the first energy range of the spectrum to calculate a corrected intensity.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
63.
RAMAN-INFRARED SPECTROSCOPIC ANALYSIS MULTIFUNCTION MACHINE, AND MEASURING METHOD EMPLOYING RAMAN SPECTROSCOPY AND INFRARED SPECTROSCOPY
A Raman-infrared spectroscopy analysis combination device including: a light source; a plate for fixing a sample; a stage on which the plate is placed; an objective optical element for obtaining Raman light; an objective optical element for obtaining reflected infrared light; a Raman light detection system; an infrared light detection system; a driving unit for adjusting a positional relationship between a position of the plate and the objective optical elements; a switching unit that switches between the detection systems; and a control unit for controlling the driving unit, the switching unit and the optical imaging elements. At least one of the plate and the stage is provided with a marker for adjusting the positional relationship, and the control unit controls the driving unit to adjust the positional relationship between the position of the plate and the objective optical elements based on a position of the marker.
G01N 21/3563 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solidsPreparation of samples therefor
An evaluation method comprises: obtaining information about a task performed by a subject (step S10); obtaining biological information of the subject (step S12); determining a timing at which the biological information satisfies a predetermined condition (step S14); outputting a portion of the information about the task corresponding to the determined timing (step S24); and receiving an input of feedback on the task (step S26).
In an ion analyzer which dissociates an ion using a radical generated from a source gas, a gas supplier (26) supplies the source gas by selecting a gas from multiple kinds of gases and/or mixing two or more of those gases. The source gas is introduced into a generation chamber (210). A power supplier (25) supplies electric power for generating electric discharge within the generation chamber. A controller (3) controls those two suppliers as follows: When the radical is to be generated from a first gas through which electric discharge is relatively difficult to occur, the electric discharge is initiated by supplying electric power into the generation chamber while a second gas through which electric discharge occurs more easily is selected or mixed with the first gas and supplied to the generation chamber. After the electric discharge is initiated, the first gas is selectively supplied to the generation chamber.
In an ion analyzer dissociating an ion originating from a sample by bringing a radical into contact with the ion within a reaction chamber, a source gas from which the radical is to be generated is introduced into a generation chamber. A power supplier supplies electric power for generating an electric discharge within the generation chamber. A source-gas supplier supplies the source gas to the generation chamber. A controller controls the source-gas supplier and the power supplier to perform, in a switchable manner, a radical introduction mode where the electric power is supplied to the generation chamber while the source gas is supplied to the generation chamber for supplying the radical to the reaction chamber, and a source-gas-only introduction mode where the electric power is not supplied to the generation chamber while the source gas is supplied to the generation chamber for supplying the source gas to the reaction chamber.
G01N 27/68 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using electric discharge to ionise a gas
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
67.
MAGNET PLATE, SEPARATION DEVICE AND AUTOMATIC DISPENSER USING MAGNET PLATE
A separation device includes a magnet plate on which a well plate having a plurality of wells is placed, which separates a sample utilizing a magnetic force, and which includes a magnet arranged at a side portion of each well to correspond to each well. One magnet is provided at a side portion of one well to correspond to the one well, and a magnetic member is arranged between the one magnet and another well adjacent to the one well.
A fluorescent X-ray analysis sample preparation instrument (10) is for pulverizing a solid pharmaceutical product (91) to be analyzed into a powder to prepare a fluorescent X-ray analysis sample, and comprises: a pulverization container (11) for housing the solid pharmaceutical product (91); and a pulverization member (12) that can be housed together with the solid pharmaceutical product (91) in the pulverization container (11). Inner surfaces (131, 132) of the pulverization container (11) and surfaces (133) of the pulverization member (12) are made of a material that has oil repellency, is harder than the solid pharmaceutical product (91), and does not contain Cd, Pb, As, Hg, Co, V, or Ni, or an impurity element specified in the guideline for management of element impurities in pharmaceutical preparations published by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
The present invention provides technology for shortening a work time for constructing a method of analysis while subjecting a sample to a pretreatment with an SPE column before the analysis in an analysis unit. In an analysis system, the first flow path (21) includes one or more solid phase separation columns. A sample from an autosampler (10) is introduced into the first flow path (21) or a second flow path (22). Then, the sample is sent from the first flow path (21) or the second flow path (22) to an analysis column in a column oven (40) and a detector (50) via a switching valve (30). Purification of the sample is performed in the first flow path (21), and purification of the sample is not performed in the second flow path (22).
G01N 30/00 - Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
G01N 30/26 - Conditioning of the fluid carrierFlow patterns
70.
Display screen or portion thereof with graphical user interface of gas chromatography
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
Andrzejewski, Roch
Entwistle, Andrew
Abstract
An apparatus and method for generating a pre-set target magnetic field condition within a spatial region in a given ambient magnetic field. A plurality of separate magnetic field generating elements (102) are placed at separate respective locations surrounding the spatial region for generating respective magnetic fields extending into the spatial region. A plurality of magnetic field sensing elements (103) placed at a plurality of respective separate locations within the spatial region for sensing respective values of the magnetic field within the spatial region. A feedback control unit (150) controls the values of the respective magnetic fields generated by each of the plurality of magnetic field generating elements in response to values of the magnetic field sensed by the plurality of magnetic field sensing elements. This is done by driving the magnetic field generating elements with respective electric currents that change the magnetic field values detected by respective magnetic field sensing elements to values corresponding to the pre-set target magnetic field condition of the magnetic field within the spatial region. Calibration of the apparatus is done by applying to respective magnetic field generating elements a calibration current.
This X-ray imaging device (100, 110) comprises: a support column (17); an X-ray detection unit (20); a support part (21) that is provided to the support column, the support part supporting the X-ray detection unit so as to be movable in the vertical direction; a grip part (23) that is provided so as to move in the vertical direction integrally with the X-ray detection unit as the X-ray detection unit moves in the vertical direction; and a first movement mechanism (33) that is provided to the support part, the first movement mechanism moving the grip part relative to the X-ray detection unit in the vertical direction.
A level of mouse Aβ1-40 and a level of mouse APP669-711 in a biological sample derived from an AD model mouse are measured by detection of markers including mouse Aβ1-40 and mouse APP669-711; an APP669-711/Aβ1-40 ratio which is a ratio of the level of mouse APP669-711 to the level of mouse Aβ1-40 is calculated; and when the ratio in the AD model mouse is higher than the same ratio in a reference mouse in which cerebral Aβ deposition is absent, it is judged that an amount of cerebral Aβ deposition in the AD model mouse is higher than an amount of cerebral Aβ deposition in the reference mouse.
A calculation method includes the steps of: calculating a third period shortened during a second period when a second cleaning solution is used in place of a first cleaning solution in a liquid chromatograph capable of batch analysis, based on an analysis time required for one-time analysis when the first cleaning solution is used, a cleaning time required for one-time cleaning, the number of calibrations per batch, the number of samples analyzed per batch, the number of batches analyzed during the first period, and a reanalysis rate that requires a reanalysis to confirm whether carryover has occurred; and calculating a second profit obtained during the second period when the second cleaning solution is used instead of the first cleaning solution, based on the third period, the number of samples analyzed per batch, the number of batches analyzed during the first period, and a first profit obtained per one-time analysis.
A sealing step of sealing a flow path (3) on an outlet side of a liquid delivery device (2) that performs continuous liquid delivery by complementarily interlocking a plurality of plunger pumps (16A; 16B); a liquid delivery step of causing the liquid delivery device (2) to perform liquid delivery at a preset diagnostic flow rate after the sealing step so that each of the plurality of plunger pumps (16A; 16B) performs at least one discharge operation; a recording step of recording a time change in the liquid delivery pressure while each of the plurality of plunger pumps (16A; 16B) executes the discharge operation during execution of the liquid delivery step; and a diagnosis step of diagnosing presence or absence of a liquid delivery abnormality during the discharge operation of each of the plurality of plunger pumps (16A; 16B) based on the behavior of the liquid delivery pressure recorded in the recording step are included.
G01M 3/28 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for pipes, cables, or tubesInvestigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for pipe joints or sealsInvestigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for valves
An atomic clock system comprises: a laser light source that outputs first laser light; a first atomic clock; a first optical modulator; a second optical modulator that receives laser light from the first optical modulator through an optical fiber, a reflection mechanism; a second atomic clock; a first frequency stabilization device; and a second frequency stabilization device.
G04F 5/14 - Apparatus for producing preselected time intervals for use as timing standards using atomic clocks
H01S 3/00 - Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
H01S 3/10 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
H01S 3/13 - Stabilisation of laser output parameters, e.g. frequency or amplitude
77.
HIGH-VOLTAGE ELECTRIC POWER SUPPLY DEVICE FOR MICROCHIP ELECTROPHORESIS DEVICE, AND MICROCHIP ELECTROPHORESIS DEVICE
This high-voltage electric power supply device capable of supplying a high voltage to a microchip electrophoresis device comprises a substrate, a plurality of high-voltage generation circuits that are arranged on an upper surface (first surface) of the substrate, and a plate-form shield member that is disposed on the first-surface side of the substrate. Each high-voltage generation circuit has a transformer, a plurality of the high-voltage generation circuits are arranged between the first surface of the substrate and the shield member 2, and the plate surface of the shield member is disposed parallel to the coil axis of each transformer.
H02M 3/28 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC
Provided is a method for analyzing bisphenol by gas chromatography, the method involving introducing, into a gas chromatograph, a sample containing bisphenol and, as an additive, a hydroxy compound with a retention index being lower than that of the bisphenol and a difference in retention index from that of the bisphenol being 2,000 or less.
This detection device (100) comprises a first gas cell (1), a first adsorbent (2), a first stimulation unit (3), a first light source (4), a first detector (5), and a measurement unit (102). A gas is introduced into the first gas cell (1). The first adsorbent (2) is filled into and disposed in the first gas cell (1) such that a first non-filled space (19) is formed inside of the first gas cell (1), and adsorbs a first target component in the gas. The first non-filled space (19) is a space not filled with the first adsorbent. The first stimulation unit (3) applies a stimulus to the first adsorbent (2) so as to desorb the first target component into the first non-filled space (19). The first light source (4) radiates light toward the first non-filled space (19). The first detector (5) detects light emitted from the first gas cell (1). The measurement unit (102) measures the first target component on the basis of the output of the first detector (5).
This interference type refractometer comprises a light source (2), a light detector (4) which detects the intensity of received light, an optical system (6; 8; 10; 12) which causes the optical path of light emitted from the light source (2) to branch into a first optical path and a second optical path, then causes the first optical path and the second optical path to merge, and guides interference light of the light from the first optical path and the light from the second optical path to the light detector, a phase modulating unit (18; 20) which is disposed on the first optical path and/or the second optical path and which electrically modulates a phase difference between the light on the first optical path and the light on the second optical path, a control unit (22) which is configured to cause a drive voltage of the phase modulating unit (18; 20) to change over time with a prescribed amplitude and periodicity, to cause the intensity of the interference light detected by the light detector (4, 4') to change over time, a storage unit (24) which stores the intensity of the interference light detected by the light detector (4, 4'), and a calculating unit (26) which performs calculation processing using the intensity of the interference light stored in the storage unit (24), wherein: the control unit (22) is configured to cause the storage unit (24) to store the change over time in the intensity of the interference light in a reference state in which no sample is present on the first optical path and the change over time in the intensity of the interference light in a measurement state in which a sample is present on the first optical path, in association with the change over time in the drive voltage of the phase modulating unit (18; 20); and the calculating unit (26) is configured to obtain an amount of change in the phase of the interference light due to the sample, using a relationship between the change over time in the intensity of the interference light and the change over time in the drive voltage, stored by the storage unit (24), in the reference state, and a relationship between the change over time in the intensity of the interference light and the change over time in the drive voltage in the measurement state, and to obtain the refractive index of the sample on the basis of the amount of change in the phase.
G01N 21/45 - RefractivityPhase-affecting properties, e.g. optical path length using interferometric methodsRefractivityPhase-affecting properties, e.g. optical path length using Schlieren methods
82.
NOISE REDUCTION PROCESSING METHOD AND NOISE REDUCTION PROCESSING APPARATUS
A noise reduction processing method according to this invention includes a step of acquiring a low-frequency signal by applying a first filter including a first filter window to a target signal, a step of estimating a noise signal by applying a second filter window including a second filter window independent of the first filter window to a high-frequency signal acquired based on the target signal and the low-frequency signal, and a step of acquiring a low-noise signal.
A data processing method acquires an output value of a magnetic field from each of one or more magnetic sensors and identifies, for each of the one or more magnetic sensors, the magnetic field resulting from the position at which the output value was derived. The data processing method generates a detection value for each of the one or more magnetic sensors by removing the magnetic field resulting from the position from the output value.
The present invention includes a housing (2) including an internal space (3) to which a combustion gas is supplied, a nozzle (4) provided with an ejection port (18) at an upper end, the nozzle (4) being configured to eject a mixed gas of a sample gas and a combustion support gas from the ejection port (18) to form a hydrogen flame at the upper end, and a collector (8) having a hollow cylindrical shape and provided above the nozzle (4) with a central axis facing a vertical direction to collect components in the sample gas ionized by a hydrogen flame formed at the upper end of the nozzle (4), wherein the nozzle (4) is provided with a first tapered surface (22) at an upper end part, the first tapered surface (22) being inclined with a first taper angle (θ1), the first tapered surface (22) reducing an outer diameter of the nozzle (4) toward the upper end, and the collector (8) is provided with a second tapered surface (24) inside a lower end part, the second tapered surface (24) being inclined with a second taper angle (θ2) larger than the first taper angle (θ1), the second tapered surface (24) reducing an inner diameter of the collector (8) upward from a lower end.
A camera captures a surface image of a sample. A reference position setting processing unit changes the focal position of the laser light with respect to the sample on a stage to set the focal position at which a spot area of the laser light on the surface image meets a predetermined first criterion as a reference position. A determination processing unit determines whether or not the light quantity incident on the slit provided in front of the detector meets a predetermined second criterion based on the change in the spot position of the laser light on the surface image by changing the focal position in the depth direction with respect to the reference position. An angle adjustment processing unit adjusts the angle of the mirror when it is determined that the light quantity incident on the slit does not meet the predetermined second criterion.
A metabolite analysis support system includes: an enzyme information storage unit for storing enzyme information representing a relation between an enzyme and metabolites for one or more enzymes involved in metabolic pathways in a body of an organism; an analysis condition storage unit for storing an analysis condition for analyzing the metabolites with a mass spectrometer; a gene locus information input unit for inputting information regarding a gene locus affecting an expression of an enzyme of interest; a metabolite identification unit for identifying the metabolites as analysis target metabolites, based on information regarding the gene locus and information stored in the enzyme information storage unit, and an analysis condition output unit for retrieving and outputting an analysis condition for analyzing the analysis target metabolite identified by the metabolite identification unit with the mass spectrometer from the analysis condition storage unit.
Provided is a technique for shortening an analysis time in relation to analysis of a polymer material. An analysis method according to the present disclosure is a method for analyzing a polymer material. Components contained in the polymer material are dissolved in a sample. In the analysis method of the present disclosure, a mass spectrometry device subjects the sample in which the polymer material has been dissolved to ionization by means of electrospray ionization. Then, in the analysis method of the present disclosure, the mass spectrometry device subjects the sample that has been subjected to ionization by the electrospray ionization to mass spectrometry.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/00 - Particle spectrometers or separator tubes
H01J 49/16 - Ion sourcesIon guns using surface ionisation, e.g. field-, thermionic- or photo-emission
H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
A sample preparation kit provides a significantly versatile analytical technique that is not affected by the diversity of antibodies, difference in species, matrix and the like. For preparing a sample to be used for detection of a monoclonal antibody through high-performance liquid chromatography-mass spectrometry (LC-MS), the kit includes a porous body for immobilizing a monoclonal antibody to be detected; nanoparticles with an immobilized protease; a reaction vessel for selectively digesting the monoclonal antibody by bringing the porous body and nanoparticles into contact; a buffer to be introduced into the reaction vessel along with the nanoparticles and porous body so that a protease reaction is carried out; and a filtration membrane to remove the porous body and nanoparticles after the proteolysis so as to extract the reaction product and the buffer.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
C12N 11/02 - Enzymes or microbial cells immobilised on or in an organic carrier
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
C12Q 1/37 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving peptidase or proteinase
G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
A method for adjusting a cooling device (100) comprises: a step for preparing a cooling device in which the volume of a gas phase portion (1a) of a tank (1) for storing a refrigerant (101) is changed to adjust the pressure of an inert gas (6) sealed in the gas phase portion of the tank, thereby adjusting the evaporation temperature of the refrigerant; and a step for adjusting the rate of change in the evaporation temperature of the refrigerant with respect to a charge in the volume of the gas phase portion of the tank, by adjusting the amount of the inert gas or the amount of the refrigerant to be filled in the cooling device.
F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes
91.
PRETREATMENT METHOD, ANALYSIS METHOD, PROGRAM, AND ANALYSIS SYSTEM
This pretreatment method of a biological cell-containing sample for infrared spectroscopic analysis comprises: a step for preparing a first acidic solution containing an organic acid; and a step for bringing cells into contact with the first acidic solution.
G01N 21/3563 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solidsPreparation of samples therefor
C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
G01N 33/483 - Physical analysis of biological material
A mass spectrometer capable of performing scan measurement, includes: a provisional event time determining unit to determine a provisional event time to be assigned to a scan measurement event, which is a measurement unit for performing one scan measurement, in accordance with an analysis condition specified by a user; a scan speed selection unit to select a scan speed from candidates such that a measurement time required for one scan measurement does not exceed the provisional event time of the scan measurement event; an event time determining unit to correct the provisional event time of the scan measurement event to a time required for scan measurement under the selected scan speed, and set the provisional event time that has been corrected as an event time of the scan measurement event; and a control information creation unit to create control information for controlling the mass spectrometer based on the event time.
A controller comprises: an input unit that receives an input of an experimental protocol designed in a directed graph; a generation unit that generates a dependency list including first dependency information indicating that start of processing of a second node depends on completion of processing of a first node; a selection unit that selects from a plurality of nodes a node at which processing is started based on the dependency list; a command unit that instructs an experimental device to execute the processing of the selected node; and an updating unit that updates the dependency list when any processing of the plurality of nodes is completed, the updating unit updating the first dependency information from first information to second information, the selection unit selecting the second node when the first dependency information is updated from the first information to the second information.
A first mobile phase is supplied by a mobile phase supplier. A sample is supplied by a sample supplier to the first mobile phase supplied by the mobile phase supplier. The sample supplied by the sample supplier passes through a separation column. The sample that has passed through the separation column is detected by a detector. Based on a detection result provided by the detector, sample components that have passed through the separation column are collected by a trap column. A make-up solution is supplied to the detector by a liquid sender, and an eluent for eluting a sample is supplied to the trap column by the liquid sender.
B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
B01D 15/24 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
An extraction analysis device includes a placement table for placing a rack holding a plurality of extraction containers, and an analysis channel for analyzing a component extracted from a sample, and is configured to set the plurality of extraction containers held in the rack placed on the placement table as extraction targets in a preset order, to execute an extraction operation for extracting components from a sample to a mobile phase that is a supercritical fluid in the extraction container set as the extraction target, and to execute analysis of the components by introducing the components extracted by the extraction operation into the analysis channel. A rack replacement device is configured to execute replacement of the rack on the placement table by performing movement of the rack from the placement table of the extraction analysis device and placement of the rack on the placement table. The extraction analysis device is configured to bring the rack into a movable state in which the rack can be moved from the placement table during the analysis of a component extracted from a sample by the extraction operation in the extraction container set as a last extraction target among the plurality of extraction containers held in the rack. The rack replacement device is configured to execute replacement of the rack on the placement table during the analysis of the component extracted by the extraction operation in the extraction container set as the last extraction target.
A pretreatment method for the analysis of a metabolite includes: a step for supplying an analysis target sample to a porous carrier to support a metabolite contained in the analysis target sample on the porous carrier; and a step for supplying a vaporized derivatization reagent to the porous carrier to which the metabolite has been supported, thereby derivatizing the metabolite.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
Efficiency of automatic execution of an experimental protocol is improved. A specific application executed in a terminal device sets a first parameter according to an amount of a sample contained in a specific container used in the experimental protocol. The specific application sets a second parameter according to a change in the amount of the sample in specific processing using the specific container in the experimental protocol. A controller automatically executes the experimental protocol based upon the first parameter and the second parameter. The specific application updates the first parameter based upon the second parameter.
A circulation device for a two-phase cooling system includes an inlet connection, an outlet connection, and a bypass line branching at a portion downstream of a pump and upstream of the inlet connection to allow a refrigerant to flow to a condenser without passing through the inlet connection and the outlet connection, and is operable to circulate the refrigerant not through the inlet connection and the outlet connection but through the bypass line when an evaporator is not connected to the inlet connection and the outlet connection.
An information processing system includes: a measuring device that measures advanced glycation end products (AGEs) of a user and is provided with identification information of a supporter who supports the user; and a server device that communicates with the measuring device and a supporter terminal of the supporter. The measuring device outputs a measurement result of the AGEs in association with the identification information to the server device. The server device stores the measurement result in association with the identification information and outputs information about the measurement result to the supporter terminal.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
