A method for calibrating a mass spectrum in mass spectrometry of a microorganism sample containing a target substance that is a molecule to be analyzed, including (S31) obtaining a mass spectrum of the microorganism sample to which one or more types of molecules having a smaller estimated theoretical m/z than the target substance are added as a first standard substance; (S32) setting, as a second standard substance, one or more types of molecules derived from the microorganism sample and having a larger estimated theoretical m/z than the target substance; and (S33) calibrating the mass spectrum based on an actual m/z of the first standard substance corresponding to peaks of the mass spectrum and an actual m/z of the second standard substance corresponding to peaks of the mass spectrum, and the theoretical m/z of the first standard substance and the theoretical m/z of the second standard substance.
A trained-model storage section (44) holds two trained models. The first trained model, constructed by machine learning in which a first window is applied to first reference waveform data, outputs a first index representing a peak portion or non-peak portion for first partial data. The second trained model, constructed by machine learning in which a second window having a different width from the first window is applied to second reference waveform data, outputs a second index representing a peak portion or non-peak portion for second partial data. A first-index output processor (55) inputs first analysis-target partial data into the first trained model to obtain an output of the first index. A second-index output processor (56) inputs second analysis-target partial data into the second trained model to obtain an output of the second index. A peak portion estimator estimates a peak portion from the outputs of the first and second indices.
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
3.
LAMP LIGHTING DEVICE, FLUORESCENCE DETECTOR AND CHROMATOGRAPH
A lamp lighting device is used to light a discharge lamp provided as a light source in a fluorescence detector. The discharge lamp has a configuration in which an anode and a cathode are arranged to be opposite to each other in a discharge container. The lamp lighting device includes a lamp driver, a lamp-voltage detector and a deterioration determiner. The lamp driver drives the discharge lamp. The lamp-voltage detector detects a lamp voltage in a monitoring period until a discharge state reaches a predetermined stable state after a discharge lamp in an unlit state is lit due to electrical breakdown. The deterioration determiner determines a deterioration state of the discharge lamp based on a detected lamp voltage.
An estimation method includes: obtaining a measurement value of advanced glycation end products of a subject; and estimating, using a correlation between a measurement value of advanced glycation end products and a blood glucose spike frequency prepared in advance, a blood glucose spike frequency of the subject based on the measurement value of advanced glycation end products of the subject obtained in the obtaining.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
An underwater optical wireless communication system (100) according to this invention includes a first communication device (2) for rotating together with a rotating body (1) underwater; and a second communication device (3) for wirelessly communicating with the first communication device (2) in a direction intersecting a rotation axis (60) of the rotating body, wherein the first communication device includes a first light emitter (20) for emitting first light (50), and a first information converter (21) for converting state information (40) input from a state information detector (4) for detecting the state information, which is information on the state of the rotating body, into the first light, and the second communication device includes a second light receiver (30) for receiving the first light.
H04B 10/112 - Line-of-sight transmission over an extended range
G08C 15/06 - Arrangements characterised by the use of multiplexing for the transmission of a plurality of signals over a common path successively, i.e. using time division
H04B 13/02 - Transmission systems in which the medium consists of the earth or a large mass of water thereon, e.g. earth telegraphy
A sample plate holder (6) for a mass spectrometer includes biasing members (631 to 633) configured to push one surface of a sample plate (5) toward the other surface, and contact members (612 to 614) configured to abut on the other surface of the sample plate at three positions not located on a straight line in plan view. The sample plate holder (6) can be suitably used in a mass spectrometer (1) including a laser light irradiation unit (13) configured to irradiate a sample(S) placed on the sample plate with laser light and a mass spectrometry unit (30) configured to perform mass spectrometry of ions generated from the sample by irradiation with the laser light.
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
H01J 49/16 - Ion sourcesIon guns using surface ionisation, e.g. field-, thermionic- or photo-emission
A mass spectrometer includes: an LIT to trap ions derived from a sample in a trap space extending along a linear axis and eject a part of the ions from the trap space to an outside; an ion guide unit to receive and deliver the ions to a latter stage, the ion guide unit including an ion inlet to receive the ejected ions, an ion outlet to send the received ions and/or ions generated from the received ions to a latter stage, and an ion passage path having a cross-sectional area decreasing as the ions travel from the ion inlet to the ion outlet; a bunching unit to bunch the ejected ions to form an ion bunch and to send the ion bunch to a downstream side; and a mass spectrometry unit to separate and detect, according to a m/z, ions contained in the ion bunch.
One mode of an imaging analysis apparatus according to the present invention includes: a measurement unit configured to acquire analysis result data by performing ion mobility mass spectrometry for each of a plurality of micro regions in a predetermined measurement region in a sample; a correlation investigation unit (22, 23) configured to investigate a correlation between an m/z and an ion mobility in the analysis result data based on the analysis result data acquired by the measurement unit; and a data reduction unit (24, 25) configured to reduce an amount of the analysis result data by limiting an ion mobility range according to the m/z or limiting an m/z range according to the ion mobility based on the correlation obtained by the correlation investigation unit.
A method for manufacturing a flow path unit (10) through which a high-temperature gas flows and which comprises a first metal body (1) having a first surface (11) and a second metal body (2) having a second surface (21), a flow path being formed by combining the first metal body (1) and the second metal body (2), the method comprising: a step for sandwiching a thermoplastic polyimide member (3) between the first surface (11) and the second surface (21); a step for applying pressure between the first surface (11) and the second surface (21); and a step for raising the temperature of the member (3) to the heat-resistance temperature of the thermoplastic polyimide or higher and thereby bonding the first metal body (1) and the second metal body (2) in a state in which the flow path is enclosed.
A waveform-analyzing device includes a trained-model storage section (44) for a trained model which detects a peak from a waveform. The model is constructed by machine learning using reference waveform data as teaching data. Each reference waveform has a different baseline shape and a known position of a peak portion including an overlap peak, with tailing processing, complete separation or vertical partitioning related to this peak. For an input of measurement data, the model outputs an index which represents a single-peak, overlap-peak or non-peak portion and to which the tailing processing, complete separation or vertical partitioning is related as a peak separation technique. A n index outputter (55-57) inputs analysis-target data into the model to obtain an output of the index which represents a single-peak, overlap-peak or non-peak portion and to which the tailing processing, complete separation or vertical partitioning is related as the technique for separating the overlap-peak portion.
This X-ray imaging apparatus (100) is equipped with an imaging control unit (6) that controls an X-ray source (1) so that X-ray irradiation is performed by a subset of electron emission units (12) selected from a plurality of electron emission units (12), for each imaging angle (40) when acquiring a plurality of projection image data (50), and also control a selection of a second electron emission unit (42) different from a first electron emission unit (41) used in immediately preceding X-ray irradiation when performing X-ray irradiation.
H01J 35/14 - Arrangements for concentrating, focusing, or directing the cathode ray
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
A method for classifying a microorganism, including (S1) obtaining a first mass spectrum resulting from mass spectrometry of a first microorganism belonging to the order Enterobacterales that has been cultured under conditions for producing an acid shock protein, classification of the first microorganism at and below one of the family, genus, and species levels being unknown; (S2) obtaining a first m/z corresponding to the acid shock protein from the first mass spectrum; and (S3) performing classification at or below one of the unknown levels of the first microorganism by analyzing the first m/z.
A scanning probe microscope includes an observation device configured to output an observation signal acquired by observing a sample containing particles, and an information processing device. The information processing device is configured to acquire the observation signal, generate an observation signal based on the observation signal each time the observation signal corresponding to one observation region of the observation device is acquired, count the number of particle images included in the observation image each time the observation image is generated, terminate an acquisition of the observation signal when a counted total number of particle images becomes greater than a predetermined threshold, and execute a particle analysis on a generated observation image.
A method for processing a coaxial cable (60) for applying a voltage to a time-of-flight mass spectrometer (10) includes a folding processing step S2 and a burying processing step S3. In the folding processing step S2, a folded portion (66a) is formed by folding a tip end portion of a shield wire (66) to the outer sheath (68) side with respect to the coaxial cable (60) including a central conductor (62), an insulator (64) provided around the central conductor (62), the shield wire (66) provided around the insulator (64), and the outer sheath (68) provided around the shield wire (66). In the burying processing step S3, a buried member (74) having insulating property or semiconductivity is disposed in a gap (72) formed between the folded portion (66a) and the insulator (64).
An advice device comprises a computing device and a communication device communicably connected to the computing device. The communication device obtains a measurement value of an advanced glycation end product of a subject and a plurality of other data of the subject that are different from the measurement value of the advanced glycation end product. The computing device generates advice information for the life of the subject based on the measurement value of the advanced glycation end product obtained by the communication device and at least one of the plurality of other data obtained by the communication device.
G16H 20/90 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to alternative medicines, e.g. homeopathy or oriental medicines
16.
METHOD FOR PREPARING SAMPLE SOLUTION CONTAINING NEUROGRANIN-RELATED PEPTIDE AND METHOD FOR ANALYZING NEUROGRANIN-RELATED PEPTIDE
Provided is a method for analyzing a neurogranin-related peptide capable of suppressing variations in analysis results, and a method for preparing a biological sample containing a neurogranin-related peptide used therein. The method includes mixing a biological sample containing a neurogranin-related peptide with an organic solvent having a relative polarity of 0.200 or more and 0.700 or less to prepare a sample solution having a final concentration of the organic solvent of 5.0 (v/v) % or more.
A mass spectrometer includes: measurement execution units separate and detect product ions according to a mass-to-charge ratio, generated by irradiating a precursor ion of a sample component with an oxygen radical, a hydroxyl radical, or a nitrogen radical; a candidate molecule estimation unit to determine a candidate molecule assuming that the sample component is a compound having a heterocyclic ring containing a double bond between carbon atoms based on the mass-to-charge ratio of the precursor ion; an assumed product ion estimation unit to calculate a mass-to-charge ratio of an assumed product ion assumed to be generated by dissociation of the heterocyclic ring of the precursor ion of the candidate molecule or a bond adjacent to the heterocyclic ring; and a determination unit to determine whether the sample compound is the candidate molecule by comparing the mass-to-charge ratio of the detected product ion with th at of the assumed product ion.
A technical solution of the present disclosure provides an ion guide device including a first electrode group and a second electrode group. On a cross section perpendicular to an ion optical axis, n first planar electrodes of the first electrode group and n second planar electrodes of the second electrode group are arranged alternately with one another in a circular shape, Each of the first planar electrodes and each of the second planar electrodes are applied with different direct current potentials, in an extension direction of the ion optical axis, respective cross-sectional sizes or distances from the ion optical axis of the first planar electrode and the second planar electrode are changed in opposite ways so as to form a direct current potential gradient in the extension direction of the ion optical axis. In particular, at least one side surface of the first planar electrode and/or the second planar electrode, which is different from an end surface in a length direction, is a positioning plane, and the positioning plane is used for determining a position where the first planar electrode and/or the second planar electrode are made or assembled.
A data processing method includes: obtaining a feature amount of a target component and a measurement value of the target component from a first chromatogram, the first chromatogram being obtained by analyzing a target sample; obtaining feature amounts and measurement values of reference components from second and third chromatograms, the second and third chromatograms being obtained by analyzing a standard sample; and correcting the measurement value of the target component based on the feature amount of the target component, the feature amounts of the reference components and the measurement values of the reference components.
An analysis system includes an analysis apparatus including an element to be used for an analysis operation. The analysis system includes a terminal apparatus that shows information on the analysis operation by the analysis apparatus. In the analysis system, the terminal apparatus is configured separately from the analysis apparatus. The analysis apparatus includes a holding portion for holding the terminal apparatus.
A dye-containing volatile liquid containing a dye at a predetermined concentration is prepared by dissolving the dye in a volatile liquid; the dye-containing volatile liquid is sucked by a dispenser and dispensed into a measurement container; the dye-containing volatile liquid dispensed into the measurement container is dried; after the drying, a predetermined amount of a low-volatility liquid having volatility lower than the volatility of the volatile liquid is added to the measurement container to dissolve the dye, thus preparing an evaluation liquid; optical measurement is performed on the evaluation liquid; and the dispensing amount which is a volume of the dye-containing volatile liquid dispensed into the measurement container is determined based on a measured value of the evaluation liquid by the optical measurement, an amount of the low-volatility liquid added, and a concentration of the dye in the dye-containing volatile liquid.
Provided is a method for analyzing an O-linked sugar chain subjected to linking mode-specific modification of sialic acid, the method including a modification step of adding a modifier that subjects the O-linked sugar chain to linking mode-specific modification of sialic acid, to a sample including a glycoprotein to which the O-linked sugar chain is linked, a releasing step of releasing the O-linked sugar chain subjected to linking mode-specific modification of sialic acid, from the glycoprotein, and an analysis step of analyzing the released O-linked sugar chain subjected to linking mode-specific modification of sialic acid.
The present invention comprises a negative electrode 21 that emits electrons, a rotary positive electrode 23 that generates X-rays due to the electrons emitted from the negative electrode 21, a housing 29 that holds an outer ring 27C of a rotary bearing 27, a preload spring 35 that applies a preload to the outer ring 27C, and a sliding member 39 that is disposed between the outer ring 27C and the preload spring 35 and slides along the inner peripheral surface of the housing 29. The sliding member 39 is provided with a first sliding portion 51 that can slide along the inner peripheral surface of the housing 29, a second sliding portion 53 that is disposed at a prescribed distance from the first sliding portion 51 and can slide along the inner peripheral surface of the housing 29, and a groove portion 55 that is formed between the first sliding portion 51 and the second sliding portion 53.
Provided is a method for estimating a structure of an oligonucleotide in which a plurality of nucleotides are linked by one or more phosphoramidate bonds or phosphorodiamidate bonds, using a mass spectrometer including an ion source employing a MALDI method, said method comprising: a preparation step for preparing an analysis sample including the oligonucleotide and a matrix; a mass spectrometry step for generating fragment ions by cleaving, in the mass spectrometer, a P-N bond involved in the linkage between the nucleotides in at least one of the phosphoramidate bonds or the phosphorodiamidate bonds of the oligonucleotide contained in the analysis sample, and detecting the fragment ions using the mass spectrometer; and a structure estimation step for estimating at least a portion of the structure of the oligonucleotide by analyzing the result of the mass spectrometry obtained in the mass spectrometry step.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/16 - Ion sourcesIon guns using surface ionisation, e.g. field-, thermionic- or photo-emission
25.
METHOD FOR ANALYZING MORPHOLINE RING-CONTAINING OLIGONUCLEOTIDE
This method for analyzing a morpholine ring-containing oligonucleotide is configured such that a morpholine ring-containing oligonucleotide contained in a sample is analyzed with a matrix-assisted laser desorption/ionization mass spectrometer using a mixed matrix containing 3-hydroxypicolinic acid (3-HPA) and 2',4',6'-trihydroxyacetophenone (THAP). This method uses a matrix suitable for the ionization of molecules of a morpholine ring-containing oligonucleotide by the MALDI method, and it is thus possible to more reliably measure the molecular weight of a morpholine ring-containing oligonucleotide in mass spectrometry using the MALDI method.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
A61K 31/787 - Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
A pipe connecting structure is configured so that a fluid connection of a pipe to a port is established by insertion of a tip portion of the pipe to a predetermined position in the port. The pipe connecting structure includes a pressing structure that is in contact with an outer peripheral surface of the tip portion of the pipe inserted to the predetermined position of the port and generates pressing force toward a center of the port on the outer peripheral surface of the tip portion of the pipe. Further, the pipe connecting structure is configured so that a center of the tip portion of the pipe and a center of the port substantially coincide with each other by pressing force generated by the pressing structure when the tip portion of the pipe is inserted to the predetermined position of the port.
F16L 19/07 - Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends adapted for use in socket or sleeve connections
F16L 21/04 - Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings in which sealing rings are compressed by axially-movable members
27.
SCANNING PROBE MICROSCOPE AND METHOD FOR CONTROLLING SCANNING PROBE MICROSCOPE
This scanning probe microscope comprises: a measurement unit including a probe for measurement; and a controller for controlling the measurement unit. Upon acquisition of an instruction for starting the measurement, the controller identifies a predicted value of a total of drift amounts in the measurement when the measurement is started at the timing of acquiring the instruction. The predicted value is based on reference information that defines a temporal change in the drift amounts. The controller starts the measurement when the predicted value is smaller than a predetermined threshold value, and avoids the start of the measurement when the predicted value is equal to or larger than the threshold value.
This radiographic imaging device comprises: a storage unit for storing a trained model (74a) that, by receiving as input a first image (81) and a second image (82) captured at different time points, generates a motion vector (9v) of an object in the first image (81) to the second image (82), and generates, on the basis of the motion vector (9v), an intermediate image (81a) at an intermediate time point between the time point at which the first image (81) was captured and the time point at which the second image (82) was captured; and a control unit. The control unit, after acquiring the motion vector (9v) by inputting the first image (81) and the second image (82) into the trained model (74a), sets tracking points (9a, 9b) in the second image (82) on the basis of the tracking points (9a, 9b) in the first image (81) and the acquired motion vector (9v).
Provided is a method for quantifying a specific component contained in a measurement sample. The method includes: obtaining a measurement spectrum at each of a plurality of points in time by analyzing the measurement sample with chromatography; deriving an index value at each point of the plurality of points in time, by applying a filter for extracting the specific component, to the measurement spectrum at the point of the plurality of points in time; obtaining a chromatogram by arranging one or more index values at respective one or ones of the plurality of points in time; and quantifying the specific component based on a peak of the chromatogram.
Provided is a method for quantifying a specific component contained in a measurement sample. The method includes: obtaining a measurement spectrum at each of a plurality of points in time by analyzing the measurement sample with chromatography; deriving an index value at each point of the plurality of points in time, by applying a filter for extracting the specific component, to the measurement spectrum at the point of the plurality of points in time; obtaining a chromatogram by arranging one or more index values at respective one or ones of the plurality of points in time; and quantifying the specific component based on a peak of the chromatogram.
This water quality analyzer comprises: a syringe pump for sucking and discharging a liquid; a plurality of containers for storing mutually different kinds of liquids; a switching mechanism to which a first flow passage leading to the syringe pump is fluidically connected and a plurality of second flow passages respectively leading to the plurality of containers are fluidically connected, and which is configured to selectively connect any one of the plurality of containers to the syringe pump; a liquid sensor which is provided such that a signal outputted varies depending on the presence or absence of the liquid inside the first flow passage, or which is provided such that a signal outputted differs between when the liquids are present inside all of the plurality of second flow passages and when the liquids are present inside only a part of the plurality of second flow passages; and a container management unit which is configured to detect, on the basis of the signal outputted from the liquid sensor, whether or not an unusable container exists among the plurality of containers.
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
This agitating device comprises: a placement part on which can be placed a well plate in which a specimen is accommodated; a first shaft body extending along a first axis; a second shaft body extending along a second axis different from the first axis; a first transmission part for transmitting a force rotating around the first axis of the first shaft body as a force for vibrating the well plate placed on the placement part; and a second transmission part for transmitting a force rotating around a fourth axis of the second shaft body as a force for vibrating the well plate placed on the placement part.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
34.
MICROFLUIDIC DEVICE, CONNECTION DEVICE, AND LIQUID CHROMATOGRAPH
This microfluidic device comprises a body portion composed of one or a plurality of members. The body portion includes a connection portion that is connectable to the separation column, and a plurality of flow passages. The plurality of flow passages include a sample holding portion for holding a sample, and an introduction flow passage capable of introducing a sample into a separation column for separating the sample. The microfluidic device further comprises a switching member slidably connected to the body portion and capable of selectively connecting by switching connection of the plurality of flow passages by sliding with respect to the body portion.
A method for a structural analysis of a sample molecule using a mass spectrometer includes: a process for obtaining a standard analysis condition for each of setting items for performing a molecular-related ion measurement, where the setting items include an ion amount setting item, a mass-to-charge-ratio range setting item, and a signal intensity setting item; a process for performing a product ion measurement under an altered analysis condition, to acquire mass spectrum data of the product ion measurement, where the altered analysis condition is prepared by changing at least one of analysis conditions of the ion amount setting item, the mass-to-charge-ratio range setting item and the signal intensity setting item in the standard analysis condition; a process for extracting peaks corresponding to the fragment ions; and a process for determining at least a portion of the structure of the sample molecule based on mass information of the extracted peaks.
[Problem] Provided is an X-ray imaging apparatus that can reduce a burden on an operator and time required for examination.
[Problem] Provided is an X-ray imaging apparatus that can reduce a burden on an operator and time required for examination.
[Solution] Provided are an X-ray tube 5 that irradiates a subject M with X-rays, an X-ray detector 7 that detects X-rays transmitted through the subject M, an operating unit 19 that is located at a position where a level thereof changes together with a level of at least either the X-ray tube 5 or the X-ray detector 7 constituting an imaging system and receives input operation by an operator S, an optical camera 21 that acquires information on a physique of the operator S, and a level control unit 45 that controls a level of the operating unit 19 to be a level F1 suitable for the input operation by the operator S in accordance with the information on the physique.
A specimen treatment apparatus may include a centrifugation device including a plurality of vial holders, the plurality of vial holders being arranged evenly on a same circumference an operating device holding two dispensers, the two dispensers being arranged side by side in parallel with each other in a state where ends of the two dispensers face vertically downward, the operating device being configured to simultaneously move the two dispensers, and a controller configured to control operations of the centrifugation device and the operating device, wherein a distance between the ends of the two dispensers is substantially the same as a distance between centers of two vial holders disposed parallel to an alignment direction of the two dispensers by the centrifugation device, and the controller is configured to dispose two vial holders holding vials to be accessed by the two dispensers in parallel with the alignment direction by controlling the centrifugation device, and to cause the two dispensers to simultaneously access the two vials to be accessed disposed in parallel with the alignment direction by controlling the operating device.
An X-ray fluorescence spectrometer (10) includes: a sample stage (2); an X-ray tube (7) that radiates excitation X-rays toward the sample stage (2); a detector (8) that detects fluorescent X-rays emitted from a sample on the sample stage; and a control device (14) that controls the X-ray tube (7) and the detector (8). Assuming that an intensity of X-rays that are part of the fluorescent X-rays, of a material of an X-ray tube target, emitted from the X-ray tube (7) and are Rayleigh scattered by the sample(S) placed on the sample stage (2) is defined as IR and that an intensity of X-rays that are Compton scattered is defined as IC, when the control device (14) creates a calibration curve by irradiating the standard sample with the excitation X-rays from the X-ray tube (7) and when a value of IR/IC obtained for the standard sample is out of a reference range, the control device (14) issues a warning.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
39.
MASS SPECTROMETRY METHOD, AND ICP MASS SPECTROMETRY DEVICE
In a sample introduction step, a liquid sample is introduced into an ICP mass spectrometry device via a liquid chromatograph. In an internal standard element introduction step, a solution of an internal standard element is mixed with the liquid sample introduced in the sample introduction step without interposing the liquid chromatograph to introduce the internal standard element. In a first chromatogram acquisition step, a first chromatogram 81 is acquired by mass spectrometry for each component in the liquid sample introduced in the sample introduction step. In a second chromatogram acquisition step, a second chromatogram 82 is acquired by mass spectrometry for the internal standard element introduced in the internal standard element introduction step. In a first correction step, the first chromatogram 81 is corrected using the second chromatogram 82.
One embodiment of this flow path structure includes a housing having a cavity therein and having a plurality of openings leading to the cavity, and a flow path member disposed inside the cavity of the housing and having a communication flow path for fluid communication of the plurality of openings.
To reduce deformation of a stator in an upper-lower direction. A vacuum pump includes a rotor housed in a housing and rotationally driven, plural stages of rotor blades provided in the rotor, and plural stages of stators, each of which is disposed between adjacent ones of the plural stages of rotor blades. The stator has an inner peripheral rib, an outer peripheral rib, and a stator blade connecting the inner peripheral rib and the outer peripheral rib, and is housed in the housing in a state of the outer peripheral rib being sandwiched between spacers. At least part of the outer peripheral rib of the stator is provided with a deformable portion configured to allow deformation of the inner peripheral rib and/or the stator blade in a radial direction.
The mass spectrometer according to the present disclosure is a mass spectrometer that generates a group of product ions from a precursor ion derived from a sample component having a hydrocarbon chain and performs mass spectrometry thereon, and includes a reaction chamber, an electrode, an introduction unit, a mass separation unit, a detection unit, a power supply unit, and a controller. The controller performs mass spectrometry on the sample component while alternating between a first analysis mode in which ions are detected in a first polarity mode and in a multimode, and a second analysis mode in which ions are detected in a second polarity mode and in a single mode.
A mass spectrometry method including: a preparation step (step 1) of adding a predetermined alkali metal ion to a liquid sample; an ionization step (step 3) of ionizing a target compound contained in the liquid sample to which the alkali metal ion has been added; and a measurement step (step 7) of measuring an intensity of an adduction formed in the ionization step by an addition of the predetermined alkali metal ion to the target compound, or an intensity of a product ion derived from the adduct ion.
Provided is an angle adjustment member for an optical element, the angle adjustment member including: two actuators; and a center bar of which a tip portion is movable in 360°. Furthermore, in order to provide a micro-Raman spectroscopic device capable of performing adjustment of an optical axis without opening a device housing and capable of further performing fine adjustment of the optical axis with out imposing an excessive burden on an adjuster, at least one of an incident light optical element and a Raman light optical element has the angle adjustment member.
A phase contrast X-ray imaging apparatus (100) according to this disclosure includes an X-ray source (1); an X-ray detector (2); a plurality of gratings; an image processor (7a) for generating a first dark field image (35a); a storage (8) for storing a plurality of correction curves (20a) generated at positions in a direction perpendicular to a grating direction; and a controller (7b) for correcting the first dark field image by using the correction curves corresponding to the positions, wherein each of the plurality of correction curves represents an assignment relation between values that relate to X-ray absorption of a subject (90) and values that relate to X-ray scattering of the subject at corresponding one of the positions.
G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers
G01N 23/083 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the radiation being X-rays
46.
Accelerated Deterioration Test Apparatus, Accelerated-Deterioration-Test Analysis System, and Accelerated Deterioration Test Method
An accelerated deterioration test apparatus (101) according to this invention includes a container (10) configured to be able to accommodate a sample (200) as a subject of an accelerated deterioration test for accelerating deterioration of the sample (200) as the test subject by using a deterioration factor for deteriorating the sample; and an introducer/collector (120) connected to the container (10) to introduce a gas or a liquid as the deterioration factor into the container (10) and to collect, during the accelerated deterioration test, a product that appears with the deterioration of the sample (200).
A flow-path switching device includes a column pipe connected to the separation column, a first rotating body which has a first port and a first sliding surface, and in which a first through hole penetrating the first port and the first sliding surface is formed, and a second rotating body having a second sliding surface facing the first sliding surface, wherein the second rotating body is rotatable with the first sliding surface being in contact with the second sliding surface, and a second through hole is formed in the second rotating body, one end of the second through hole is connectable to the first through hole when a rotation position of the second rotating body with respect to the first rotating body is a first position, and another end of the second through hole is connected to the column pipe.
Provided is a mass spectrometry method for post-translational modification and/or fragmentation of tau protein in a biological fluid, the method enabling stable detection of both modified endogenous tau fragments that include post-translational modification sites such as phosphorylation, and unmodified endogenous tau fragments, without requiring the performance of additional fragmentation processing on a group of endogenous tau fragments in the biological fluid. The method includes: a step of extracting endogenous tau fragments derived from tau protein in a biological fluid sample to obtain a group of endogenous tau fragments; a step of performing mass spectrometry on the group of endogenous tau fragments to obtain mass-to-charge ratio (m/z) and intensity information for each of the endogenous tau fragments, and thereby conducting mass profiling of the group of endogenous tau fragments; and a step of analyzing at least one of the difference in fragmentation of tau protein and the difference in post-translational modifications of tau protein between samples by comparing the mass profiling results of the groups of endogenous tau fragments between samples.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
49.
METHOD AND APPARATUS FOR CONSTRUCTING DATABASE FOR MICROBIAL IDENTIFICATION
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Ogata, Koretsugu
Sekiguchi, Yuji
Miura, Daisuke
Abstract
A method of constructing a microbial identification database, the method comprising: (ST02) acquiring genome data for microorganisms from a genome database; (ST06) determining whether a criterion is satisfied by the genome data thus acquired; (ST16) for respective sets of the genome data that were determined that they satisfied the criterion, predicting proteins to be expressed; and (ST20A, 20C) constructing a mass-to-charge ratio database including mass-to-charge ratio lists, the mass-to-charge ratio lists being predicted for the respective sets of the genome data based on the proteins thus predicted.
A data processing method is performed by a computer to correct measurement values of a prescribed component obtained by measurement with an analysis device. The data processing method includes: receiving the measurement values; and calculating a first reference value and a second reference value using the measurement values. The data processing method includes correcting the measurement values using the first reference value and the second reference value.
A mass spectrometer according to an embodiment of the present invention comprises a voltage generation unit (53) that generates an RF voltage to be applied to an electrode forming a quadrupole mass filter. The voltage generation unit includes: an RF signal generation unit (530) that generates a sine wave signal using a DDS; a first filter (531) that removes high-frequency noise superposed on the sine wave signal; a waveform conversion unit (5320) that receives a sine wave signal that is an output of the first filter as an input, and generates a rectangular wave signal having a frequency of 1/N (where N is an integer of at least one) of the frequency of the sine wave signal; and a second filter (5321) that converts the rectangular wave signal generated by the waveform conversion unit into a sine wave signal, by removing high-frequency components from the rectangular wave signal.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Sekiguchi, Yuji
Miura, Daisuke
Abstract
A microbial identification method comprising: (ST32) acquiring a sample list that is a list of mass-to-charge ratios for a sample; (ST40 to ST44, ST40A) identifying the sample by comparing the sample list with a mass-to-charge ratio database with weights assigned to mass-to-charge ratios for proteins included in a specific group, the mass-to-charge ratio database being a database of mass-to-charge ratio lists respectively for microorganisms predicted from genome data; and (ST50, ST54) outputting results of the identifying.
The fluorescent X-ray analysis method includes: placing a sample in a fluorescent X-ray analysis apparatus (S1); calculating a reference tube current of an X-ray tube by applying a desired dead time rate to a paralyzed model (S3); determining a measurement tube current of the X-ray tube based on the reference tube current and irradiating the sample with X-rays generated by applying the measurement tube current to the X-ray tube (S4); and analyzing fluorescent X-rays obtained by irradiating the sample with the X-rays (S5). Thus, a desired dead time of the counting circuit can be obtained with high accuracy.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
55.
X-RAY IMAGING SYSTEM AND X-RAY IMAGE DISPLAY METHOD
An X-ray imaging system according to this invention includes an X-ray irradiator for irradiating a subject who is in loaded action in which a load is applied to legs of the subject with X-rays; an X-ray detector; a load information acquirer for acquiring load information to identify a state of the load applied to the leg or the legs in the loaded action of the subject separately from the detection of the X-rays; a display; and a controller. The controller executes control for identifiably displaying at least an X-ray image that corresponds to a maximum load timing in which a largest load is applied to one of legs of the subject in loaded action on the display based on the load information.
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 5/103 - Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
This liquid chromatograph comprises: a sample injection flow path; an analysis pump that guides a mobile phase to the sample injection flow path; a sample injection unit that guides a sample to the sample injection flow path; a flow path switching unit; a separation column that separates the sample that has passed through the sample injection flow path; and a detector that detects the sample that has passed through the separation column. The sample injection flow path includes: a first merging unit that is connected to the sample injection unit and the analysis pump; a weighing flow path; and a first branching unit.
A method of processing structured data related to an experiment includes creating structured data by using a computer, and generating a control signal for operating an automatic experimental apparatus based on the structured data. The structured data includes a plurality of sets of items and values for conducting a predetermined experiment with the automatic experimental apparatus. The creating the structured data includes extracting, from a first information source, a first value to be input to the set, and adding a second value to a blank field of the set.
G06F 16/483 - Retrieval characterised by using metadata, e.g. metadata not derived from the content or metadata generated manually using metadata automatically derived from the content
In an ion source 100 configured to generate ions by a process involving an electric discharge, at least the surface of at least an anode 121 of discharging electrodes included in the ion source is made of titanium in order to prevent a decrease in the power output of the ion source due to the formation of an oxide film on an electrode surface. Titanium has the nature that it forms a film on its surface through oxidization and yet does not lose its electric conductivity even when oxidized. Therefore, the power output of this ion source will not decrease even when an oxide film is formed on the surface of the anode, so that it can be used for a long period of time without requiring the electrode polishing or similar tasks.
A nebulizer includes: a nozzle portion provided with an ejection port through which gas is ejected; and a capillary having a tip end portion disposed to protrude from the ejection port. A plurality of protruding portions protruding inward in a radial direction of the ejection port are arranged side by side in a circumferential direction on a portion of an inner circumferential surface of the nozzle portion, the portion of the inner circumferential surface defining the ejection port. The plurality of protruding portions are provided to define an inscribed circle. The capillary passes through inside the inscribed circle.
An X-ray imaging apparatus according to this invention includes an X-ray-image-and-voice-information collector for collecting a plurality of X-ray images based on detection results of X-rays with which a patient is irradiated, and for collecting voice information on the patient's voice input from a voice information input part; an X-ray image preserver for preserving the plurality of X-ray images collected together with time information; a voice information preserver for preserving the voice information collected together with time information; a timing identifier for identifying a timing in which the speech of the patient is different from the examination sentence based on the voice information preserved; an X-ray image identifier for identifying a corresponding X-ray image that corresponds to the timing in the plurality of X-ray images preserved; and a display controller for directing a display to display the corresponding X-ray image.
Provided is a gas chromatograph capable of efficiency circulating air in a column oven. The gas chromatograph is provided with a column oven, a heater, a fan, and a cylindrical member. The column oven accommodates a column. The heater heats the inside of the column oven. The fan has a blade that rotates about a rotation axis in the column oven, and sends air toward the column provided in the axial direction that is a direction along the rotation axis. The cylindrical member is arranged to accommodate at least a part of the fan in a state of being spaced apart from the column in the axial direction and surrounding an outer periphery of the fan along a rotational direction of the blade.
A vacuum pump includes a housing having a suction port, a rotor housed in the housing and rotationally driven to suck gas through the suction port and pump the gas, and a lid member that covers a recess of the rotor. The lid member has a cone shape having a vertex on a side close to the suction port and having a bottom on a side close to the rotor. The generatrix of the cone shape includes a first curved portion having such a curve that an angle between a tangent to the generatrix and a gas flow direction increases from a vicinity of the vertex to a vicinity of the bottom.
A computer (132) obtains image data (step S10), extracts from the image data as an edge pixel a pixel satisfying a condition that a result of comparing with an adjacent pixel is an edge (step S12), and generates first data by dilating an edge including the edge pixel (step S14). Then, the computer (132) uses the first data to generate second data that determines a region in a sample corresponding to a substrate (step S22).
A method for nucleic acid structure analysis using an ion trap type mass spectrometer having an ion source performing MALDI includes: an ionization step of ionizing a nucleic acid contained in a sample by the ion source; an ion dissociation step of dissociating a protonated molecule or a deprotonated molecule of the nucleic acid generated in the ionization step by collision-induced dissociation inside an ion trap of the mass spectrometer to generate a plurality of fragment ions; a mass spectrometry step of performing mass spectrometry on the plurality of fragment ions generated in the ion dissociation step to acquire mass information of the plurality of fragment ions; and a structure determination step of determining at least a part of a structure of the nucleic acid based on the mass information of the plurality of fragment ions acquired in the mass spectrometry step.
A sample information setting method for setting information on a sample in an injection device for injecting a sample into each of a plurality of injection targets, includes a step of displaying a plurality of first images corresponding to the plurality of injection targets, respectively; a step of displaying a second image showing, as a menu, information on at least one sample capable of being set to the injection target corresponding to the first image included in a region within an array of the plurality of injection targets, in response to completion of a first operation of selecting the region by a dragging operation, the region including the first image of the injection target; and a step of setting the information on the sample selected by a second operation to the injection target corresponding to the first image included in the region.
This method for identifying acid shock proteins comprises: (i) a step for preparing a first solution containing an acid shock protein produced by a predetermined type of microorganism at a first concentration and a second solution containing the acid shock protein produced by the predetermined type of microorganism at a second concentration lower than the first concentration; (ii) a step for measuring a first mass spectrum and a second mass spectrum corresponding respectively to the first solution and the second solution; and (iii) a step for comparing the first mass spectrum and the second mass spectrum to determine a specific peak corresponding to the acid shock protein in each mass spectrum in accordance with the degree to which the peak intensity is maintained in the second mass spectrum.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
68.
X-Ray Imaging Apparatus and Method for Adjusting Current to Be Supplied to Filament
An X-ray imaging apparatus includes an X-ray tube including an electron emitter including a filament, a storage to store current information acquired in advance, in which a total supply time of a current to be supplied to the filament is associated with an appropriate current value to be supplied to the filament, and a controller configured or programmed to perform a control to adjust the current to be supplied to the filament based on the current information after a first total supply time as a predetermined total supply time.
H05G 1/46 - Combined control of different quantities, e.g. exposure time as well as voltage or current
G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
The X-ray imaging system generates a three-dimensional model of a device based on a first X-ray image and a second X-ray image. The X-ray imaging system determines an inaccurate portion of the shape in the three-dimensional model (81) by identifying a parallel portion extending along a direction parallel to the epipolar line, from the device having a linear structure. The X-ray imaging system displays the three-dimensional model and a display based on the determination result of the inaccurate portion of the shape in the three-dimensional model.
Provided is a non-contact sleep state measurement system 100 capable of accurately measuring a sleep state regardless of age, disease, or the like of a subject. The sleep state measurement system includes: a frame image acquisition unit that acquires frame images including a subject P during sleep in time series; a difference information calculation unit that calculates difference information that is information indicating a difference between two frame images at different times; a subject attribute information acquisition unit that acquires subject attribute information that is information indicating an attribute of the subject; and a sleep state related information calculation unit that calculates sleep state related information that is information related to a sleep state of the subject using the difference information or secondary information obtained therefrom as an explanatory variable according to the subject attribute information.
A holder holds a battery which is subjected to X-ray analysis. The battery includes a positive electrode and a negative electrode. A sample chamber for disposing the battery therein is formed inside the holder. The holder includes a body, a beryllium plate, a first resin member, a conductive member, a positive electrode terminal, and a negative electrode terminal. An upper surface of the body is formed with a window. The beryllium plate is arranged in the window. The first resin member is provided on a surface of the beryllium plate. The conductive member is provided between the positive electrode and the first resin member so as to be in contact with the positive electrode of the battery. The positive electrode terminal is electrically connected to the conductive member. The negative electrode terminal is electrically connected to the negative electrode.
G01N 23/2209 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using wavelength dispersive spectroscopy [WDS]
G01N 23/207 - Diffractometry, e.g. using a probe in a central position and one or more displaceable detectors in circumferential positions
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
An analytical method for performing, in parallel, a first analysis step of introducing a non-derivatized first sample 132 into a first column 44 together with a first mobile phase 54, and analyzing components contained in the first sample 132; and a second analysis step of introducing a derivatized second sample 137 into the second column 84 together with a second mobile phase 94, and analyzing components contained in the second sample 137, wherein the first sample 132 contains inosinic acid and guanylic acid, and in the first analysis step, by separating components contained in the first sample 132 using the first column 44 having a length of 185 mm or more, a chromatogram is obtained in which peaks corresponding to inosinic acid and guanylic acid are separated with a separation degree of 1.5 or more.
Provided is a biomagnetism measurement apparatus in which sufficient consideration is given to the fact that optimal arrangement of a sensor with respect to a subject varies depending on the purpose of the measurement. The biomagnetism measurement apparatus of the present invention has the following configuration. That is, the biomagnetism measurement apparatus of the present invention includes: a magnetic sensor group that is disposed outside a body of a subject and measures biomagnetism of the subject; and an arithmetic device that acquires an arrangement pattern of the magnetic sensor group corresponding to a content of the measurement based on information indicating the content of the measurement.
A mass spectrometer (100) comprises an ionization chamber (200), ion guides (23, 25), a detector (28), and a control device (3). The control device is configured to execute a determination process. The determination process includes: a process of measuring a first ion intensity; a process of measuring a second ion intensity when a first period has elapsed after the measurement of the first ion intensity; a process in which the polarity mode is switched from a first polarity mode to a second polarity mode after the measurement of the second ion intensity, the polarity mode is returned to the first polarity mode when a second period shorter than the first period has elapsed, and a third ion intensity is measured; and a process of outputting a display signal for displaying, to a user, a determination result that the degree of contamination of the ion guides satisfies a contamination criterion.
A mass spectrometer (1) capable of performing mass spectrometry by generating ions from a sample through a first ionization method and a second ionization method comprises: an ion transport optical system (211, 212, 221, 222, 231, 232) into which generated ions are introduced and which includes a plurality of electrodes arranged along a flight path of the ions; a mass spectrometry unit provided with mass separation parts (242, 252, 254, 255, 256) for separating the ions according to the mass-to-charge ratio ; a storage unit (51) in which information on a first applied voltage to be applied to the plurality of electrodes is stored; a second applied voltage generation unit (53) that, when the first applied voltage includes a value of a voltage that forms a rising gradient of a potential inside the ion transport optical system, changes the value of the voltage to generate a second applied voltage in which the rising gradient is suppressed; and an analysis execution unit (54) that applies the second applied voltage to the plurality of electrodes and performs mass spectrometry of ions generated through the second ionization method.
A gas flow path switching device (1) comprises: a plate-like flow path plate (250); a first microvalve (201); and a second microvalve (202). A first flow path (271), a second flow path (272), and a third flow path (273) are formed in the flow path plate (250). The first microvalve (201) is configured to be able to switch connection and disconnection between the first flow path (271) and the second flow path (272). The second microvalve (202) is configured to be able to switch connection and disconnection between the first flow path (271) and the third flow path (273). The first microvalve (201) and the second microvalve (202) are arranged on both surfaces (250a, 250b) of the flow path plate (250).
G01N 30/26 - Conditioning of the fluid carrierFlow patterns
G01N 30/46 - Flow patterns using more than one column
80.
METHOD FOR FORMULATING ANALYSIS SAMPLE OF COMPONENT DERIVED FROM BIOPOLYMER-PRODUCING MICROORGANISM, ANALYSIS METHOD, AND METHOD FOR IDENTIFYING BIOPOLYMER-PRODUCING MICROORGANISM
A method for formulating an analysis sample of a component derived from a biopolymer-producing microorganism according to the present invention comprises: a step for preparing a sample solution containing constituent components of the microorganism and the biopolymer; a step for centrifuging the sample solution; a step for performing ultrafiltration of a supernatant obtained through the centrifugation; and a step for formulating an analysis sample using a filtrate or a residue obtained through the ultrafiltration.
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
A first diffraction grating (11) is installed at a first position (P1) and diffracts and spectrally resolves X-rays from an X-ray source (3). A second diffraction grating (12) is installed at a second position (P2) and diffracts and spectrally resolves X-rays from the X-ray source (3). Blocking parts (41, 42) are configured so as to be able to block both a first optical path (71) of the X-rays from the X-ray source (3) diffracted by the first diffraction grating (11) and incident on a detector and a second optical path (72) of the X-rays from the X-ray source (3) diffracted by the second diffraction grating (12) and incident on the detector (2). A control device (91) controls the blocking parts (41, 42) so as to selectively block one of the first optical path (71) and the second optical path (72).
G21K 1/06 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diffraction, refraction, or reflection, e.g. monochromators
A classification method according to the present invention comprises: a first step for focusing on target particles in a separation channel; a second step for subjecting the target particles to a cross flow flowing in a first direction, and then distributing the target particles in the first direction in the separation channel; a third step for distributing the target particles after the second step in the longitudinal direction in the separation channel such that a first particle group and a second particle group included in the target particles can flow out, in that order, from an outlet port of the separation channel; a fourth step for subjecting the second particle group after the third step to a reversed cross flow flowing in a second direction, which is the direction opposite to the first direction, thereby moving the second particle group in the second direction from the side of a membrane in the separation channel; a fifth step for causing the first particle group and the second particle group to flow out, in that order, from the outlet port to outside of the separation channel; and a sixth step for detecting, using a detector, the second particle group that has been made to flow out through the outlet port.
B03B 5/62 - Washing granular, powdered or lumpy materialsWet separating by hydraulic classifiers, e.g. of launder, tank, spiral or helical chute concentrator type
G01N 15/02 - Investigating particle size or size distribution
83.
Laser Beam Irradiation Apparatus and Laser Processing Apparatus
A laser beam irradiation apparatus (1) includes a plurality of laser light sources (10), an optical fiber (30), and a coupling optical system (20). The coupling optical system (20) includes a reduction optical system (22). The reduction optical system (22) includes a lens (23a) and a lens (24a). The lens (23a) is made of a first glass material. The lens (24a) is made of a second glass material. A second energy gap of the second glass material is greater than a first energy gap of the first glass material.
A cell image analysis system (100) according to this invention includes a data tree creator (11), a graph creator (12), and a display controller (13). The display controller is configured to display a second data tree (24b) that is different from a first data tree (24a), and has horizontal and vertical axis parameters that are common to the first data tree, and, when the second data tree is selected by a user, to update a graph by adding the analysis results of cell images (30) that are included in the second data tree selected by the user to the graph.
This teaching device is for setting a reference position of a rotor (16) of a multi-port valve (2) configured so as to switch, according to rotation of the rotor (16), a communication state between a plurality of connection ports (14) for fluidly connecting piping. The teaching device comprises: the multi-port valve (2); a control unit (12) that controls the operation of the multi-port valve (2); and sensors (8; 30) provided so that an output signal changes according to the position of the rotor (16) of the multi-port valve (2). The control unit (12) is configured to rotate the rotor (16) by small angles while reading the output signal of the sensors (8; 30) in teaching for setting the reference position of the rotor (16), and to set the reference position on the basis of the value of the output signal of the sensors (8; 30).
F16K 31/04 - Operating meansReleasing devices electricOperating meansReleasing devices magnetic using a motor
F16K 11/074 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members with flat sealing faces
Laser beams condensed by a condensing optical system are incident on an optical fiber (200). An irradiation mechanism (301) irradiates an object with light that comes out of the optical fiber (200). A movement mechanism (302) moves an irradiation region in the object irradiated with laser beams. The optical fiber (200) includes a core including an incidence plane on which laser beams condensed by the condensing optical system are incident. The incidence plane is in such a first elongated shape that a first direction is longer than a second direction, the first direction and the second direction being orthogonal to each other. The irradiation region is in a second elongated shape corresponding to the first elongated shape. The movement mechanism (302) moves the irradiation region in the first direction.
An image generator built by machine learning is stored in an image-generator storage section (31). The image generator receives an image having a missing region and fills that region with a complementary image. An inspection target image is stored in an image storage section (32). A missing-image generator (44) generates, from the inspection target image, a missing image (63) in which a region is missing, a window (62) having a specified shape and size being applied on the region. A complemented-image generator (45) generates a complemented image (65) having the region filled with a complementary image by inputting the missing image into the image generator. A difference acquirer (46) determines a difference (66) between the inspection target image and the complemented image. A determiner (47) determines whether the region is normal or abnormal by comparing the difference with a predetermined criterion.
G01N 23/18 - Investigating the presence of defects or foreign matter
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
88.
Management System, Server, Method, and Non-Transitory Computer Readable Medium
A management system that provides a virtual space to a user includes a user apparatus used by the user, a sensor configured to observe change over time of a target present in a real space, and a server configured to transmit information for providing the virtual space to the user apparatus. The server is configured to obtain a detection result by the sensor, calculate a degree of change of the target based on the detection result, and arrange in the virtual space, an object representing the target on which the degree of change is reflected.
A device for processing mass spectrometry data (40) includes: a storage section (41) which holds information in which reagent-identifying information is related to the mass-to-charge ratio of an ion to be generated from the reagent; a display section (60); a mass-spectrum-data input receiver (42); a reagent-information input receiver (45) configured to receive an input of the reagent identification information of a reagent added to a sample; a peak locator (46) configured to compare the inputted reagent identification information with the information stored in the storage section, and to locate a peak associated with an ion generated from the reagent; and a display processor (47) configured to create a mass spectrum from the mass spectrum data, and to display, on the display section, the mass spectrum in such a manner that the peak located by the peak locator is shown in a form distinguishable from other peaks.
The present disclosure relates to the field of ion mobility analysis, and specifically provides a tandem U-shaped ion mobility spectrometer and an ion mobility analysis method. The tandem U-shaped ion mobility spectrometer includes two U-shaped ion mobility analyzers coupled in series. A first U-shaped ion mobility analyzer operates in a filter mode, and a second ion inlet of a second U-shaped ion mobility analyzer is disposed corresponding to a first ion outlet. An ion dissociation device is configured to receive and dissociate ions from the first U-shaped ion mobility analyzer and release fragment ions generated by the dissociation to the second U-shaped ion mobility analyzer. The tandem U-shaped ion mobility spectrometer reduces a complexity and a precision requirement of applying an electric field, has a high resolution and a dynamic range, and is suitable for studies of complex topics such as biomics.
There is provided a highly flexible sterilization method that is also safe and optimal. This sterilization method includes sterilization area setting in order to set in advance a sterilization area within a predetermined area of human activity, peripheral area setting in order to set in advance peripheral areas that are adjacent to or in proximity to the sterilization area, irradiation mode deciding in order to decide an irradiation mode for irradiating sterilization electromagnetic waves onto the sterilization area based on peripheral area information acquired from the peripheral areas, and sterilization electromagnetic wave irradiating in order to irradiate sterilization electromagnetic waves onto the sterilization area in the irradiation mode.
An X-ray imaging device (100) comprises: an imaging part (2) that includes an arm (22) that connects an X-ray source (20) and a detector (21); a drive part (3) that moves the arm (22); a touch operation button (81) that receives an operation for changing the imaging angle of the imaging part (2); and a control part (9) that, each time the touch operation button (81) is operated, performs control to move the arm (22) in a prescribed direction by the drive part (3) and change the imaging angle by a unit angle amount (change width θ).
In a mass spectrometer, a linear ion trap unit (2) has an ion-capturing space formed by rod electrodes (20) surrounding a central axis (C) and an auxiliary electrode (21) provided outside an ion-ejection end of the rod electrodes or protruding from the ion-ejection end. An extracting electrode (23) is located further outside the auxiliary electrode. An RF voltage generator (50) applies RF voltages to the rod electrodes and the auxiliary electrode to create an RF electric field within the ion-capturing space. An extracting voltage generator (52) applies a DC voltage to the extracting electrode so that a DC electric field for ion extraction reaches the ion-capturing space. A controller (4) controls the RF and extracting voltage generators to eject ions from the ion-capturing space along the central axis according to their m/z by changing the RF voltage or the DC voltage when the ions are confined within the ion-capturing space.
The disclosure relates to the field of ion mobility analysis, and particularly provides a tandem ion mobility spectrometer and an ion mobility analysis method. The tandem ion mobility spectrometer incorporates an ion dissociation device into a basic structure of a UMA, enabling ion mobility spectrometric analysis of ions within a target mobility range as well as fragment ions resulting from dissociation of the ions, achieving higher resolution. Additionally, by configuring an electric field in a first channel to allow ions to accumulate therein, when the ions within the target ion mobility range are released, ions outside the target ion mobility range which need to be analyzed can remain stored in the first channel and be released for analysis later, making ion utilization more efficient.
Provided is a method for measuring a measurement sample containing a hypochlorite ion by liquid chromatography mass spectrometry, the method including selecting a mass chromatogram indicating the presence of a hypochlorite ion-derived iron complex from a plurality of mass chromatograms obtained by liquid chromatography mass spectrometry to determine an abundance of the hypochlorite ion.
A monitoring analysis device includes a reaction product acquirer that sequentially acquires reaction products produced by a reaction device, an analyzer that sequentially analyzes the reaction products acquired by the reaction product acquirer, an analysis controller that causes the analyzer to execute a batch analysis in which a plurality of set analyses are sequentially executed according to a set analysis condition, and an analysis condition changer that, during execution of the batch analysis by the analyzer, and during or after execution of any analysis among the plurality of set analyses, is configured to change the set analysis condition for an analysis that is to be executed after the any analysis and is subject to a change.
This X-ray imaging device (100, 110) comprises: a storage unit (3) that stores registered imaging information (30) containing a plurality of registered target positions (P); and a control unit (5) that performs control to move at least one of an X-ray imaging unit (2) and a top plate (11) to a set target position that has been set. The control unit (5) is configured to set a first-selected first target position (P1) as the set target position without receiving an input operation for starting a first mode after at least one of the X-ray imaging unit 2 and the top plate 11 has been moved to a last-selected second target position (P3).
This X-ray imaging system (100) comprises: an X-ray imaging device (1) provided with an X-ray irradiation unit (10) and an X-ray detection unit (11); a detection unit (12) for detecting a subject (101); an input reception unit (3); and a control device (2) that performs control for starting, on the basis of the subject being detected, measurement of a positioning time (40), which is the time until alignment of the subject and the X-ray irradiation unit is completed, ending measurement of the positioning time and acquiring the positioning time on the basis of receipt of an operation input performed by an operator after positioning of the subject and the X-ray irradiation unit is completed, and outputting the acquired positioning time.
Provided is an ion analyzer for analyzing an ion using radical-induced dissociation. A generator (21, 210) generates a radical from a source gas. A gas supplier (26, 3) supplies a gas mixture as the source gas to the generator during an analysis. The gas mixture is prepared by mixing a first gas which is a source for a radical having oxidizing power or which itself has oxidizing power, and a second gas which is a source for a radical having reducing power or which itself has reducing power, at a predetermined ratio specified so that the efficiency of dissociation by the radical originating from the first gas is not lower than that when the second gas is not mixed. A radical generated by the generator is introduced into a reaction chamber (132), within which an ion originating from a sample is dissociated by coming in contact with the radical.
G01N 27/68 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using electric discharge to ionise a gas
