Provided is a cell culture test device including a plurality of well units. Each of the well units includes an inlet portion through which a first fluid and a second fluid are introduced and a bottom portion including a first sub-well including a first fluid-accommodating space. The first fluid-accommodating space has an edge groove formed along the outer circumference of the lower end thereof to accommodate a portion of the first fluid or increases in diameter in a direction from the upper end to the lower end thereof.
The present invention relates to a rapid antibiotic susceptibility test and an identification method capable of rapidly providing information on antibiotics suitable for microorganisms by performing an antibiotic susceptibility test and an identification test in a single process. The present invention provides a rapid antibiotic susceptibility test and an identification method comprising the steps of: (a) transferring a sample taken from a patient to a first reaction space in which a sample separation means is present; (b) separating and concentrating the pathogen in the sample from the patient's sample by capturing them with the separation means within the first reaction space; and (c) performing the identification of the pathogen or an antibiotic susceptibility test.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Engineering surveying; technological advisory services relating to technological research; technological advisory services relating to scientific research; providing information relating to scientific research; biotechnological research; scientific research in the field of biomedicine; biochemical research; bacteriological testing; pharmaceutical research and development; medical research laboratory services for predicting disease; pharmaceutical research; providing biopsy services for medical research; blood testing services for medical research; consultation and providing medical research information in the field of medical physics; consultation pertaining to pharmacology; medical research; design and development of computer software related to measuring machines and instruments; design and development of computer hardware related to measuring machines and instruments; blood analysis services for scientific purposes; basic and clinical research in the field of respiratory science and medicine; chemical research Health services, namely, performing biopsies for treatment and diagnosis of disease; blood testing being medical analysis services for diagnostic and treatment purposes provided by medical laboratories; medical consultations; providing health information; blood analysis services for diagnostic purposes provided by medical laboratories
The present invention relates to a cartridge for gene extraction and detection, which can select an appropriate antibiotic for a patient at an early stage through identification of infection-causing bacteria or strains and multiple detection of antibiotic resistance gene information. The present invention provides a system for gene extraction and detection, comprising: a cartridge in which a plurality of side chambers are arranged outside a central chamber, and a PCR channel is included at one upper side; a first temperature control unit that maintains at a constant temperature a space where the cartridge is installed; a pump that is connected to an upper part of the cartridge and pressurizes and depressurizes the central chamber; a fixing part that fixes the upper part of the cartridge; a rotating part that rotates a lower part of the cartridge and allows the side chambers and the central chamber to communicate at a desired position; a magnetic material that fixes internal magnetic beads of the cartridge; a second temperature control unit that controls the temperature of the central chamber; a third temperature control unit that controls the temperature of the PCR channel; and a detection part that detects the fluorescence of the PCR channel after PCR is completed.
The present invention relates to a cartridge for gene extraction and detection, wherein identification of bacteria or strains causing infectious diseases and multi-detection of antibiotic resistance genes are performed to enable early selection of antibiotics appropriate for a patient. The present invention provides a cartridge for gene extraction and detection, comprising: a first body including a plurality of side chambers arranged outside a central chamber thereof; the central chamber located in the central part of the first body; a lower reagent moving means configured to rotate at the bottom of the central chamber and connect the side chamber to the central chamber; and a pump connected to the upper part of the central chamber to pressurize or depressurize the interior of the central chamber.
The present invention relates to a rapid antibiotic susceptibility test and identification method capable of rapidly providing antibiotic information suitable for microorganisms by performing an antibiotic susceptibility test and an identification test in a single process. The present invention provides a rapid antibiotic susceptibility test and identification method comprising the steps of: (a) transferring a sample taken from a patient to a first reaction space in which a sample separation means is present; (b) capturing the bacteria in the sample in the first reaction space by means of the separation means, thereby separating and concentrating bacteria from the patient sample; and (c) performing the identification of the bacteria or an antibiotic susceptibility test.
C12Q 1/24 - Methods of sampling, or inoculating or spreading a sampleMethods of physically isolating an intact microorganism
7.
ANTIMICROBIAL SUSCEPTIBILITY TESTING DEVICE, ANTIMICROBIAL SUSCEPTIBILITY TESTING METHOD USING THE TESTING DEVICE AND SYSTEM INCLUDING THE TESTING DEVICE
An antimicrobial susceptibility testing device according to an embodiment of the present invention includes a substrate and a driving unit rotating the substrate. The substrate includes first injection holes formed so as to penetrate the upper surface thereof and channels forming passages therein through which antibiotics, a bacteria sample or mixed solutions thereof injected through the first injection holes are movable and having first regions where the mixed solutions are concentrated and localized by centrifugal force applied when the substrate is rotated by the driving unit.
The present invention relates to a nucleic acid analysis device including an infectious agent separation and concentration function. The present invention provides a nucleic acid analysis device including an infectious agent separation and concentration function, the device comprising: a first body in which a plurality of side chambers with closed upper portions are arranged outside a central chamber; a second body coupled to a lower portion of the first body and forming a lower portion of the side chamber; a third body coupled to a lower portion of the second body; and a lower reagent moving means that connects the central chamber and the side chambers by rotating at the lower end of the central chamber, wherein the central chamber, which passes through the center of the first body, extends upward so as to be formed in the center of the third body.
Provided is a cell culture test device including a plurality of well units. Each of the well units includes a first inlet portion through which a first fluid is introduced, a first accommodation space communicating with the first inlet portion to accommodate a flow of the first fluid introduced through the first inlet portion, a second inlet portion through which a second fluid is introduced, and a second accommodation space in which the second fluid is accommodated. The second accommodation space accommodates an island structure connected with an island-connecting structure extending from the wall surface of the second accommodation space. A third inlet portion through which an antibiotic is loaded is formed above the island structure. The antibiotic loaded through the third inlet portion is fixedly accommodated on the inner and outer surfaces of the island structure.
The present invention relates to a culture broth for culturing Gram-positive bacteria that can simultaneously culturing not only general Gram-positive bacteria but also Streptococcus pneumoniae. The present invention provides a culture broth for culturing Gram-positive bacteria, comprising a meat extract, casein hydrolysate, an antioxidant enzyme, a surfactant, starch, and a solidifying agent.
Provided is a multi-well-based rapid cell culture test device designed such that fluid films with a uniform thickness are formed. The rapid cell culture test device has an array structure of a plurality of aligned well units, each of which includes a first sub-well in which a first fluid is accommodated and a barrier structure surrounding the first sub-well to define the area of the first sub-well. A capillary channel recessed from the bottom surface of the first sub-well while traversing the bottom surface is formed to accommodate the first fluid and the barrier structure is divided into a barrier portion A located adjacent to one end of the capillary channel and a barrier portion B located adjacent to the other end of the capillary channel.
Provided is a cell culture test device including a plurality of well units. Each of the well units includes an inlet portion through which a first fluid and a second fluid are introduced and a bottom portion including a first sub-well in which the first fluid is accommodated. A first stepped portion protrudes toward the center of the well unit along the circumference of the inner wall of the well unit such that the well unit has a lower portion whose inner width is smaller than that of an upper portion at the inlet portion side.
An antimicrobial susceptibility testing apparatus according to an embodiment of the present invention comprises: a substrate; and a driving unit for rotating the substrate. The substrate may comprise: a first injection hole formed to penetrate the upper surface of the substrate; and a channel which forms a path inside the substrate through which an antimicrobial, a bacterial fluid, or a mixed solution thereof injected through the first injection hole can move, and has a first region for concentrating the mixed solution in a concentrated state by centrifugal force applied as the substrate rotates by means of the driving unit.
The present invention relates to a culture medium for culturing gram-positive bacteria, the medium enabling general gram-positive bacteria and streptococcus pneumoniae to be simultaneously cultured. The present invention provides a culture medium for culturing gram-positive bacteria, comprising a meat extract, a casein hydrolysate, an antioxidant enzyme, a surfactant, starch, and a solidifying agent.
Provided is a cell culture monitoring device comprising a plurality of well units, the well units comprising: a first injection unit for injecting a first fluid; a first accommodation unit that communicates with the first injection unit so that the first fluid injected from the first injection unit flows to be accommodated therein; a second injection unit for injecting a second fluid; and a second accommodation unit for accommodating the second fluid, wherein the second accommodation unit includes an island structure connected to an island connecting structure extended from the wall of the second accommodation unit, a third injection unit into which an antibiotic agent is introduced is formed on top of the island structure, and the antibiotic agent injected from the third injection unit is accommodated and fixed on the inside and outside of the island structure.
Provided is a rapid cell culture testing apparatus having a constant fluid-film thickness, the apparatus comprising: a first sub-well for accommodating a first fluid; and a barrier structure which surrounds the first sub-well and defines the area of the first sub-well, wherein the bottom surface of the first sub-well is provided with a capillary channel, which is recessed into the bottom surface to accommodate the first fluid therein and crosses the bottom surface, and the height of a barrier portion (A) of the barrier structure, positioned adjacent to one end of the capillary channel, is greater than the height of a barrier portion (B) thereof positioned adjacent to the other end of the capillary channel, and thus, when the first fluid is injected into the first sub-well, the first sub-well is wettened by the first fluid along the inner wall of the barrier portion (A), so that a change in the water level of the first fluid located at the other end of the capillary channel, according to the aliquot of the first fluid, is minimized.
Provided is a cell culture inspection device having a plurality of well units, wherein the well unit includes: an inlet part for injecting a first fluid and a second fluid; and a bottom part including a first sub well for accommodating the first fluid, and a first stepped part protruding toward the center of the well unit along the circumference of the inner wall of the well unit is present, and thus the well unit has a lower end portion having an inner width that is narrower than the upper end portion of the inlet part side.
Provided is a cell culture-testing device comprising a plurality of well units. Each of the well units includes: an inlet part for injecting a first fluid and a second fluid; and a bottom part on which a first sub-well including a first fluid accommodation part for accommodating the first fluid is formed, wherein the first fluid accommodation part has an edge groove formed along the outer peripheral surface of the lower end thereof and is capable of accommodating a part of the first fluid or has a diameter increasing from the upper end to the lower end.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Diagnostic apparatus, not for medical purposes; sensors
[measurement apparatus], other than for medical use;
biochips; biochip sensors; bio-sensors; biochip inspection
device; biochip analyzing apparatus; diagnostic chips for
inspecting blood plasma [laboratory apparatus]; diagnostic
chips for analyzing blood plasma [laboratory apparatus];
apparatus for inspecting biochips for laboratory use;
apparatus for analyzing biochips for laboratory use;
incubators for laboratory use; incubators for bacteria
culture for laboratory use; cell culture apparatus for
laboratory use; research laboratory analyzers for measuring,
testing and analyzing blood and other bodily fluids. Fully automatic equipment for tuberculosis diagnosis;
medical apparatus for automatic diagnosis of tuberculosis;
diagnostic apparatus for measuring cancer diagnostics; test
equipment for medical use; measuring devices for medical
use; diagnostic apparatus for medical purposes; blood
analysis apparatus for diagnosis; body fluid analysis
apparatus for medical purposes; in vitro diagnostic devices
for medical purposes; blood testing apparatus; blood
analysis equipment; apparatus for blood analysis; apparatus
for taking blood samples; apparatus for taking blood; blood
cell analysis apparatus; medical apparatus and instruments
for displaying diagnostic tests; medical imaging apparatus;
diagnostic imaging apparatus for medical use; testing
apparatus for medical purposes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Diagnostic apparatus for the detection of pathogens, bacteria, viruses and fungus for laboratory or research use, not for medical purposes; measurement apparatus, namely, sensors of cell morphology, cell growth, temperature, cell density, pH, oxygen and oil level, other than for medical use; biochips for research or scientific purposes; Biochip sensors being sensor chips for scientific use; bio-sensors being sensor chips for scientific use; electronic biochip inspection device for inspecting functionality of biochips; biochip analyzing apparatus, namely, electronic biochip inspection device for inspecting functionality of biochips; laboratory apparatus in the nature of diagnostic electronic chips for inspecting blood plasma for laboratory or research purposes; laboratory apparatus in the nature of diagnostic electronic chips for analyzing blood plasma for laboratory or research purposes; apparatus for inspecting biochips for laboratory use; apparatus for analyzing biochips for laboratory use; Incubators for bacteria cultures for laboratory use; incubators for bacteria culture for laboratory use; cell culture apparatus for laboratory use, namely, cell culture plates and dishes, tissue culture flasks, cell culture hood, incubator, water bath, centrifuge, refrigerator, microscope, cell counter and sterilizer; research laboratory analyzers for measuring, testing and analyzing blood and other bodily fluids Fully automatic equipment for tuberculosis diagnosis; medical apparatus for automatic diagnosis of tuberculosis; diagnostic apparatus for measuring cancer diagnostics; test equipment for medical use, namely, antimicrobial susceptibility testing apparatus, pathogen identification testing apparatus, immunogenomic testing apparatus, MRI diagnostic apparatus, X-ray diagnostic apparatus, neuroselective sensory nerve testing devices in the nature of disposable electrodes; measuring devices for medical use, namely, medical instrument for measuring minimum inhibitory concentration; diagnostic apparatus for medical purposes for detecting sepsis, septic shock, bacteremia, cancer, infectious disease, viral disease and bacterial disease, and for testing blood sugar levels, cancer cells and DNA; blood analysis apparatus for diagnostic use; medical diagnostic apparatus for body fluid analysis; in vitro diagnostic devices for medical purposes for detecting sepsis, septic shock, bacteremia, cancer, infectious disease, viral disease, and bacterial disease; blood testing apparatus; blood analysis equipment, namely, blood testing apparatus; apparatus for blood analysis; apparatus for taking blood samples; apparatus for taking blood; blood cell analysis apparatus; medical apparatus and instruments for displaying diagnostic information for antimicrobial susceptibility tests; medical imaging apparatus; diagnostic imaging apparatus for medical use; testing apparatus for detecting sepsis, septic shock, bacteremia, cancer, infectious disease, viral disease, and bacterial disease for medical purposes
21.
Rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and automated cell image analysis system therefor
Provided are a rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and an automated cell image analysis system therefor. The antimicrobial susceptibility test is rapidly performed based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and this makes it possible to obtain highly reliable test results faster by six to seven times than the standard method recommended by Clinical and Laboratory Standards Institute (CLSI).
Provided is a multi-well-based cell culture test device having an array structure of a plurality of aligned well units. Each of the well units includes a first sub-well adapted to accommodate a first fluid, a second sub-well adapted to accommodate a second fluid, and a barrier located between the first sub-well and the second sub-well to partition the first sub-well and the second sub-well. The first sub-well has a recess in the depth direction with respect to its bottom to accommodate a solid thin film formed by solidifying the first fluid. The barrier has such a height that the first fluid does not overflow into the second sub-well when the first fluid is loaded into the first sub-well to fill the recess.
C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
C12M 1/32 - Inoculator or sampler multiple field or continuous type
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
C12M 1/00 - Apparatus for enzymology or microbiology
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Biochips; biochip analyzing apparatus; diagnostic chips for
inspecting blood plasma [laboratory apparatus]; diagnostic
chips for analyzing blood plasma [laboratory apparatus];
research laboratory analyzers for measuring, testing and
analyzing blood and other bodily fluids; computer software;
computer software for diagnosing diseases for medical
purposes. Diagnostic chips for medical purposes; medical apparatus for
automatic diagnosis of tuberculosis; diagnostic apparatus
for measuring cancer diagnostics; test equipment for medical
use; measuring instruments for medical purposes; diagnostic
apparatus for medical purposes; blood analysis apparatus for
diagnosis; body fluid analysis apparatus for medical
purposes; blood testing apparatus; blood analysis equipment;
apparatus for blood analysis; apparatus for taking blood
samples; apparatus for taking blood; blood cell analysis
apparatus; medical apparatus and instruments for displaying
diagnostic tests; medical imaging apparatus; diagnostic
imaging apparatus for medical purposes; testing apparatus
for medical purposes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Diagnostic apparatus, not for medical purposes; sensors
[measurement apparatus], other than for medical use;
biochips; biochip analyzing apparatus; diagnostic chips for
inspecting blood plasma [laboratory apparatus]; diagnostic
chips for analyzing blood plasma [laboratory apparatus];
research laboratory analyzers for measuring, testing and
analyzing blood and other bodily fluids; computer software;
computer software for diagnosing diseases for medical
purposes. Fully automatic equipment for tuberculosis diagnosis;
diagnostic apparatus for measuring cancer diagnostics; test
equipment for medical use; measuring instruments for medical
purposes; diagnostic apparatus for medical purposes; blood
analysis apparatus for diagnostic; body fluid analysis
apparatus; in vitro diagnostic devices for medical purposes;
blood testing apparatus; blood analysis equipment; apparatus
for blood analysis; apparatus for taking blood samples;
apparatus for taking blood; blood cell analysis apparatus;
medical apparatus and instruments of displaying diagnostic;
medical imaging apparatus; diagnostic imaging apparatus for
medical purposes; testing apparatus for medical purposes;
diagnostic chips for medical purposes.
25.
Bioactivity testing structure for single cell tracking using gelling agents
Mycobacterium tuberculosis, drug screening, and bacterial diagnosis. Particularly, the use of the testing structure enables DST and diagnosis of bacteria only by pretreatment without the need to concentrate human sputum samples irrespective of inoculum effect, ensuring rapid, accurate, and simple testing compared to conventional tuberculosis diagnosis or DST systems. In addition, the testing structure of the present invention simultaneously enables the diagnosis and drug susceptibility testing of tuberculosis. Therefore, the present invention provides an effective alternative to the prior art.
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Diagnostic chips for medical purposes; biochips; biochip
analyzing apparatus; diagnostic chips for inspecting blood
plasma; diagnostic chips for analyzing blood plasma;
research laboratory analyzers for measuring, testing and
analyzing blood and other bodily fluids. Fully automatic equipment for tuberculosis diagnosis;
diagnostic apparatus for measuring cancer diagnostics; test
equipment for medical use; measuring instruments for medical
purposes; diagnostic apparatus for medical purposes; blood
analysis apparatus for diagnostic; body fluid analysis
apparatus; blood testing apparatus; blood analysis
equipment; apparatus for blood analysis; apparatus for
taking blood samples; apparatus for taking blood; blood cell
analysis apparatus; medical apparatus and instruments of
displaying diagnostic; medical imaging apparatus; diagnostic
imaging apparatus for medical purposes; testing apparatus
for medical purposes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Diagnostic chips for medical purposes; biochips; biochip
analyzing apparatus; diagnostic chips for inspecting blood
plasma; diagnostic chips for analyzing blood plasma;
research laboratory analyzers for measuring, testing and
analyzing blood and other bodily fluids. Fully automatic equipment for tuberculosis diagnosis;
diagnostic apparatus for measuring cancer diagnostics; test
equipment for medical use; measuring instruments for medical
purposes; diagnostic apparatus for medical purposes; blood
analysis apparatus for diagnostic; body fluid analysis
apparatus; blood testing apparatus; blood analysis
equipment; apparatus for blood analysis; apparatus for
taking blood samples; apparatus for taking blood; blood cell
analysis apparatus; medical apparatus and instruments of
displaying diagnostic; medical imaging apparatus; diagnostic
imaging apparatus for medical purposes; testing apparatus
for medical purposes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Diagnostic chips for medical purposes, namely, biochips; biochips for research or scientific purposes; biochip analyzing apparatus; diagnostic chips for inspecting blood plasma for research or scientific purposes; diagnostic chips for analyzing blood plasma for research or scientific purposes; research laboratory analyzers for measuring, testing and analyzing blood and other bodily fluids for scientific purposes Fully automatic equipment for tuberculosis diagnosis; diagnostic apparatus for measuring cancer diagnostics; test equipment for medical use, namely, MRI diagnostic apparatus, X-ray diagnostic apparatus, neuroselective sensory nerve testing devices in the nature of disposable electrodes; measuring instruments for medical purposes, namely, medical instruments for measuring and displaying blood pressure, lung capacity; diagnostic apparatus for medical purposes for detecting cancer, for testing blood sugar levels, cancer cells, DNA; blood analysis apparatus for diagnostic use; medical diagnostic apparatus for body fluid analysis; blood testing apparatus; blood analysis equipment; apparatus for blood analysis; apparatus for taking blood samples; apparatus for taking blood; blood cell analysis apparatus; medical apparatus and instruments for displaying diagnostic results, in the nature of magnetic resonance imagers, X-ray diagnostic apparatus; medical imaging apparatus; diagnostic imaging apparatus for medical purposes in the nature of magnetic resonance imagers; testing apparatus for medical purposes, namely, MRI diagnostic apparatus, X-ray diagnostic apparatus, neuroselective sensory nerve testing devices in the nature of disposable electrodes
29.
Assay method using encoded particle-based platform
Provided is an assay method using an encoded particle-based platform. In the assay method, first, a plurality of encoded particles having codes distinguishable from one another according to kinds of included target materials are prepared. The plurality of encoded particles are provided onto a plate including a plurality of wells by pipetting, and disposed in the plurality of wells by a self-assembly method. An analyte is provided into the plurality of wells. The codes of the plurality of encoded particles disposed in the plurality of wells are decoded. The target materials of the plurality of encoded particles are released to cause a reaction between the target materials and the analyte.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
30.
Rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and automated cell image analysis system therefor
Provided are a rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and an automated cell image analysis system therefor. The antimicrobial susceptibility test is rapidly performed based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and this makes it possible to obtain highly reliable test results faster by six to seven times than the standard method recommended by Clinical and Laboratory Standards Institute (CLSI).
A microfluidic multi-well-based cell culture testing device is provided. The multi-well-based cell culture testing device has an array structure of a plurality of aligned microfluidic well units. Each of the microfluidic well units comprises an inlet through which a first fluid enters, an accommodation compartment adapted to accommodate a second fluid therein, a microfluidic channel through which the first fluid flows, and an air outlet adapted to facilitate the entering of the first fluid.
C12M 1/32 - Inoculator or sampler multiple field or continuous type
C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
C12M 1/00 - Apparatus for enzymology or microbiology
C12M 1/40 - Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
C12Q 1/18 - Testing for antimicrobial activity of a material
32.
Microstructure for capturing and releasing microorganism
Provided is a method for capture and release of microorganisms using microstructures. The method includes providing microstructures coated with a protein for attachment/detachment of microorganisms, mixing the microstructures with a solution containing substances assisting in attachment of microorganisms in a solution containing microorganisms to prepare a mixed solution, stirring the mixed solution to attach the microorganisms to the microstructures, separating the microorganism-attached microstructures from the mixed solution; and exposing the microstructures to an environment where the substances assisting in attachment of the microorganisms are present at a low concentration to detach the microorganisms from the microstructures.
C12Q 1/24 - Methods of sampling, or inoculating or spreading a sampleMethods of physically isolating an intact microorganism
C12N 11/02 - Enzymes or microbial cells immobilised on or in an organic carrier
C12N 11/06 - Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
C12N 11/08 - Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
C12N 11/14 - Enzymes or microbial cells immobilised on or in an inorganic carrier
33.
Rapid antibiotic susceptibility testing system based on bacterial immobilization using gelling agent, antibiotic diffusion and tracking of single bacterial cells
A testing method is disclosed. The testing method includes: providing a mixture solution of a gelling agent and a microbe to a gelling device; solidifying the mixture solution to form a solid thin film in which the microbe is immobilized; supplying a bioactive agent to the solid thin film and allowing the bioactive agent to diffuse into the solid thin film; and imaging the individual responses of the single microbial cells to the bioactive agent, and determining the minimum inhibitory concentration (MIC) of the bioactive agent based on the analysis of the images to obtain AST results.
Rapid antibiotic susceptibility testing system based on bacterial immobilization using gelling agent, antibiotic diffusion and tracking of single bacterial cells
A testing method is disclosed. The testing method includes: providing a mixture solution of a gelling agent and a microbe to a gelling device; solidifying the mixture solution to form a solid thin film in which the microbe is immobilized; supplying a bioactive agent to the solid thin film and allowing the bioactive agent to diffuse into the solid thin film; and imaging the individual responses of the single microbial cells to the bioactive agent, and determining the minimum inhibitory concentration (MIC) of the bioactive agent based on the analysis of the images to obtain AST results.
Rapid antibiotic susceptibility testing system based on bacterial immobilization using gelling agent, antibiotic diffusion and tracking of single bacterial cells
A testing method is disclosed. The testing method includes: providing a mixture solution of a gelling agent and a microbe to a gelling device; solidifying the mixture solution to form a solid thin film in which the microbe is immobilized; supplying a bioactive agent to the solid thin film and allowing the bioactive agent to diffuse into the solid thin film; and imaging the individual responses of the single microbial cells to the bioactive agent, and determining the minimum inhibitory concentration (MIC) of the bioactive agent based on the analysis of the images to obtain AST results.
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific and technological services and research and
design relating thereto; industrial analysis and research
services; design and development of computer hardware and
software.
Disclosed is a microcapsule encoded depending on the kind of a target substance included therein. The encoded microcapsule has a hydrophilic liquid core including the target substance and a hydrophobic shell surrounding the liquid core. The encoded microcapsule includes graphical codes introduced on the surface of the shell.
Provided are encoded polymeric microparticles and a multiplexed bioassay using the encoded polymeric microparticles. Each of the encoded polymeric microparticles includes an encoded polymeric microparticle core and a silica shell surrounding the microparticle core. Further provided is a method for producing encoded polymeric microparticles. The method includes: mixing a photocurable material with a linker having a functional group polymerizable with the photocurable material and an alkoxysilyl group; applying patterned energy to cure the mixture, followed by encoding to obtain encoded polymeric microparticle cores; and treating the encoded polymeric microparticle cores with a silica precursor to form a silica shell on each encoded polymeric microparticle core.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
G01N 33/531 - Production of immunochemical test materials
41.
Assay method using encoded particle-based platform
Provided is an assay method using an encoded particle-based platform. In the assay method, first, a plurality of encoded particles having codes distinguishable from one another according to kinds of included target materials are prepared. The plurality of encoded particles are provided onto a plate including a plurality of wells by pipetting, and disposed in the plurality of wells by a self-assembly method. An analyte is provided into the plurality of wells. The codes of the plurality of encoded particles disposed in the plurality of wells are decoded. The target materials of the plurality of encoded particles are released to cause a reaction between the target materials and the analyte.
G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
42.
Rapid antibiotic susceptibility testing system based on bacterial immobilization using gelling agent, antibiotic diffusion and tracking of single bacterial cells
A testing method is disclosed. The testing method includes: providing a mixture solution of a gelling agent and a microbe to a gelling device; solidifying the mixture solution to form a solid thin film in which the microbe is immobilized; supplying a bioactive agent to the solid thin film and allowing the bioactive agent to diffuse into the solid thin film; and imaging the individual responses of the single microbial cells to the bioactive agent, and determining the minimum inhibitory concentration (MIC) of the bioactive agent based on the analysis of the images to obtain AST results.
An optofluidic lithography system including a membrane, a microfluidic channel, and a pneumatic chamber is provided. The membrane may be positioned between a pneumatic chamber and a microfluidic channel. The microfluidic channel may have a height corresponding to a displacement of the membrane and have a fluid flowing therein, the fluid being cured by light irradiated from the bottom to form a microstructure. The pneumatic chamber may induce the displacement of the membrane depending on an internal atmospheric pressure thereof.
Provided is a method of magnetically controlling a magnetic structure, the method including: providing a solution containing magnetic structures, each including a magnetic axis in which magnetic nanoparticles are arranged; and controlling movements of the magnetic structures by applying an external magnetic field to the solution.
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
G06K 7/08 - Methods or arrangements for sensing record carriers by means detecting the change of an electrostatic or magnetic field, e.g. by detecting change of capacitance between electrodes
G06K 19/02 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the selection of materials, e.g. to avoid wear during transport through the machine
B03C 1/034 - Component partsAuxiliary operations characterised by the magnetic circuit characterised by the matrix elements
Provided is a method of fabricating a magnetic axis-controlled structure. The method of fabricating a magnetic axis-controlled structure includes providing a composition including magnetic nanoparticles dispersed in a liquid medium, applying a magnetic field to the composition to align the magnetic nanoparticles along the magnetic field and form a magnetic axis, and solidifying the liquid medium to fix the magnetic axis.
G01R 33/02 - Measuring direction or magnitude of magnetic fields or magnetic flux
B05D 5/12 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a coating with specific electrical properties
G01R 33/12 - Measuring magnetic properties of articles or specimens of solids or fluids
B05D 3/00 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
B05D 3/06 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation
46.
Optofluidic lithography system, method of manufacturing two-layered microfluidic channel, and method of manufacturing three-dimensional microstructures
An optofluidic lithography system including a membrane, a microfluidic channel, and a pneumatic chamber is provided. The membrane may be positioned between a pneumatic chamber and a microfluidic channel. The microfluidic channel may have a height corresponding to a displacement of the membrane and have a fluid flowing therein, the fluid being cured by light irradiated from the bottom to form a microstructure. The pneumatic chamber may induce the displacement of the membrane depending on an internal atmospheric pressure thereof.
