The subject matter of the present invention is the use of 2-Pentadecyl-2-oxazoline (also known as PEA-OXA) in association with butyric acid, in acidic or salified form, in the treatment of epilepsy and associated psychiatric comorbidities (such as social isolation). In particular, the present invention relates to PEA-OXA for use, in humans and animals, in the prevention and treatment of epileptogenesis and comorbidities associated with epilepsy, such as limited social interaction, wherein PEA-OXA is administered in association or in combination with butyric acid or a salt thereof, wherein said administration is separate, joint, or simultaneous.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic substances
adapted for medical use, food for babies; plasters,
materials for dressings; materials for stopping teeth and
dental wax; disinfectants; preparations for destroying
vermin; fungicides, herbicides; eyepatches for medical
purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for use in otorhinolaryngology; Food supplements for use in otorhinolaryngology; Pharmaceutical preparations and food supplements for use in otolaryngology.
7.
2-PENTADECYL-2-OXAZOLINE AS AN OPIOID ADJUVANT TO PREVENT OR TREAT HYPERALGESIA
The subject of the present invention is the use of 2-Pentadecyl-2-oxazoline (also known as palmitoylethanolamide oxazoline or PEA-OXA) to counteract hyperalgesia induced by the most common opioids (OIH) associated with microglial hyperactivation. In particular, the present invention concerns the use of PEA-OXA in humans and animals to prevent or treat some of the adverse effects of opioids by controlling immune hyperactivation, wherein said PEA-OXA is administered separately, sequentially or jointly with the opioid.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetics; non-medicated foot gels; foot creams (non-medicated-); Non-medicated foot lotions; Foot care cosmetics; Non-medicated creams, lotions and gels For podiatric use; Foot bath preparations. Pharmaceuticals; Food supplements; Gels for dermatological use; Foot gels for pharmaceutical purposes; Medicated foot gels; Creams (Medicated -) for the feet; Medicated lotions for the feet; Medicated gels for the treatment of calluses, inflammations and fungus on feet; Dermatological preparations For use on feet; Callus softening preparations.
01 - Chemical and biological materials for industrial, scientific and agricultural use
07 - Machines and machine tools
Goods & Services
Active chemical ingredients for use in the manufacture of pharmaceuticals; Collagen based ingredients for cosmetic preparations; Chemical compositions and materials for use in the manufacture of cosmetics; Chemical substances for use in the production of drugs; Vitamins for use in the manufacture of food supplements; Antioxidants for use in the manufacture of food supplements; Proteins for use in the manufacture of food supplements. Machines for chemical industry; Machines for the pharmaceutical industry.
12.
2-PENTADECYL-2-OXAZOLINE AS AN OPIOID ADJUVANT TO PREVENT OR TREAT HYPERALGESIA
2-Pentadecyl-2-oxazoline (also known as palmitoylethanolamide oxazoline or PEA-OXA) is used to counteract hyperalgesia induced by the most common opioids (OIH) associated with microglial hyperactivation. In particular, PEA-OXA is administered to humans and animals to prevent or treat some of the adverse effects of opioids by controlling immune hyperactivation. The PEA-OXA is administered separately, sequentially or jointly with the opioid.
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 31/421 - 1,3-Oxazoles, e.g. pemoline, trimethadione
A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
14.
N-PALMITOYLETHANOLAMIDE FOR USE IN COMBINATION WITH MELOXICAM IN THE TREATMENT OF INFLAMMATORY PAIN
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
Described herein are pharmaceutical compositions containing Adelmidrol. In particular, the Adelmidrol is used in the treatment of diseases characterized by insufficient specific agonism of the PPAR-gamma receptor in humans or animals, more particularly in the treatment of articular chondropathies of mechanical, toxic, iatrogenic, degenerative origin, or associated with inflammatory phenomena mainly related to organs and tissues not belonging to the osteoarticular system; fibrogenesis of the articular cartilages; chronic inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis; Irritable Bowel Syndrome (IBS); diseases characterized by an abnormal fibrosis of the connective tissue, such as systemic sclerosis, particularly of the skin and lung; eye disorders characterized by angiogenesis, fibrosis, inflammation and oxidative stress.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Sanitary preparations for medical purposes; dietetic
substances adapted for medical use, food for babies;
plasters, materials for dressings; materials for stopping
teeth and dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical drugs; Medicines for veterinary purposes; Veterinary preparations; Food supplements; Dietetic substances adapted for medical use; Dietetic substances adapted for veterinary use.
22.
N-PALMITOYLETHANOLAMIDE AND MELATONIN FOR USE IN THE TREATMENT OF AUTISM SPECTRUM DISORDER AND OTHER NEUROBEHAVIORAL DISORDERS SIMILARLY ACCOMPANIED BY RESTLESSNESS, IRRITABILITY, SLEEP DISORDERS, AND POTENTIALLY STEREOTYPIES
The present invention relates to the use of N-palmitoylethanolamide (PEA) in association with melatonin or natural precursors thereof in the treatment of autism spectrum disorder (ASD) and other neurobehavioral disorders similarly accompanied by restlessness, irritability, sleep disorders, and potentially stereotypies.
The present invention relates to the use of N-palmitoylethanolamide (PEA) in association with melatonin or natural precursors thereof in the treatment of autism spectrum disorder (ASD) and other neurobehavioral disorders similarly accompanied by restlessness, irritability, sleep disorders, and potentially stereotypies.
In particular, the present invention relates to the use of PEA in association with melatonin in the treatment of ASD, wherein the palmitoylethanolamide is administered in association with melatonin or tryptophan (TRP) or 5-hydroxytriptophan (5H-TRP), wherein said administration is separate, combined or simultaneous.
N-PALMITOYLETHANOLAMIDE AND MELATONIN FOR USE IN THE TREATMENT OF AUTISM SPECTRUM DISORDER AND OTHER NEUROBEHAVIORAL DISORDERS SIMILARLY ACCOMPANIED BY RESTLESSNESS, IRRITABILITY,SLEEP DISORDERS, AND POTENTIALLY STEREOTYPIES
The present invention relates to the use of N-palmitoylethanolamide (PEA) in association with melatonin or natural precursors thereof in the treatment of autism spectrum disorder (ASD) and other neurobehavioral disorders similarly accompanied by restlessness, irritability, sleep disorders, and potentially stereotypies.In particular, the present invention relates to the use of PEA in association with melatonin in the treatment of ASD, wherein the palmitoylethanolamide is administered in association with melatonin or tryptophan (TRP) or 5-hydroxytriptophan (5H-TRP), wherein said administration is separate, combined or simultaneous.
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
A61P 25/00 - Drugs for disorders of the nervous system
24.
Pharmaceutical composition comprising palmitoylethanolamide and L- Acetylcarnitine
It is the object of the present invention a pharmaceutical composition for use in humans or animals containing N-palmitoylethanolamide for the control of the inflammatory and/or neuropathic pain of various origin. In particular, the present invention relates to a pharmaceutical composition comprising palmitoylethanolamide (PEA and L-acetylcarnitine (LAC), optionally with in addition an antioxidant compound such as a polyphenol, alpha-lipoic acid, and L-acetylcysteine.
A61K 31/221 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Active chemical ingredients for use in the preparation of
cosmetics; active chemical ingredients for use in the
preparation of pharmaceutical products, food products,
dietary substances and food supplements for medical
purposes. Cosmetic preparations; non-medicated cosmetics and toiletry
preparations; cosmetics; non-medicated cosmetics. Dietary supplements with a cosmetic effect; pharmaceutical
drugs; pharmaceuticals; dietetic food and substances adapted
for medical or veterinary use, food for babies; dietetic
substances adapted for medical use; dietary supplements;
dietetic food supplements. Scientific research services for medical purposes; medical
research; scientific research for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic substances
adapted for medical use; plasters, materials for dressings;
materials for stopping teeth and dental wax; disinfectants.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations for the treatment of neurological disorders or neuro-inflammatory diseases; sanitary preparations for medical purposes; dietetic substances in the nature of food supplements for the treatment of neurological disorders or neuro-inflammatory diseases adapted for medical use; medical plasters
29.
N-PALMITOYLETHANOLAMIDE AND DOCOSAHEXAENOIC ACID FOR USE IN THE TREATMENT OF AUTISM SPECTRUM DISORDER AND OTHER DEPRESSIVE SYNDROMES
N-palmitoylethanolamide (PEA) is used in combination with docosahexaenoic acid (DHA) in the treatment of autism spectrum disorder and other depressive syndromes. In particular, N-palmitoylethanolamide (PEA) is used in combination with docosahexaenoic acid (DHA) in the treatment of diseases having decreased endogenous levels of allopregnanolone.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 25/00 - Drugs for disorders of the nervous system
The present invention relates to the use of N-palmitoylethanolamide (PEA) in combination with docosahexaenoic acid (DHA) in the treatment of autism spectrum disorder and other depressive syndromes.In particular, the present invention relates to the use of N-palmitoylethanolamide (PEA) in combination with docosahexaenoic acid (DHA) in the treatment of diseases characterized by decreased endogenous levels of allopregnanolone.
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 25/00 - Drugs for disorders of the nervous system
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Active chemical ingredients for use in the manufacture of cosmetics; active chemical ingredients for use in the manufacture of pharmaceutical products, food products, dietary substances and food supplements for medical purposes Cosmetic preparations; non-medicated cosmetics and toiletry preparations; cosmetics; non-medicated cosmetics Dietary supplements with a cosmetic effect; pharmaceutical drugs, namely anti-inflammatory pharmaceutical drugs aimed at treating chronical conditions presenting mood and behavioral disorders; pharmaceuticals, namely anti-inflammatory pharmaceuticals aimed at treating chronical conditions presenting mood and behavioral disorders; dietetic food and dietetic substances in the nature of natural compounds being food supplements adapted for medical or veterinary use; food for babies; dietetic substances in the nature of natural compounds being food supplements adapted for medical use; dietary supplements; dietetic food supplements Scientific research services for medical purposes; medical research; scientific research for medical purposes
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Active chemical ingredients for use in the preparation of cosmetics; active chemical ingredients for use in the preparation of pharmaceutical products, food products, dietary substances and food supplements for medical purposes.
(2) Anti-aging cosmetic preparations, antioxidant, for the improvement of skin appearance and the reduction of signs of aging;
(3) Dietary supplements with a cosmetic effect for use in reducing inflammation, supporting cognitive and neurological health, improving mood, and delaying age-related physiological decline; pharmaceuticals for use in reducing inflammation, supporting cognitive and neurological health, improving mood, and delaying age-related physiological decline; anti-inflammatory dietary supplements for human use; dietetic food supplements to support the nervous system and immune system function. (1) Scientific research services for medical purposes relating to neuroinflammation, aging, and behavioral disorders; medical research relating to neuroinflammation, aging, and behavioral disorders.
33.
COMPOSITION OF N-PALMITOYL-ETHANOLAMIDE AND BAICALEIN IN CO-MICRONIZED FORM
A composition is based on N-palmitoyl-ethanolamide and Baicalein in the co-micronized form. The includes a mixture of palmitoyl-ethanolamide (PEA) and Baicalein in co-micronized form. The composition is usable for treating benign prostatic hyperplasia.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
It is the object of the present invention a composition based on N-palmitoyl-ethanolamide and Baicalein in the co-micronized form.In particular, the present invention relates to a composition comprising a mixture of palmitoyl-ethanolamide (PEA) and Baicalein in the co-micronized form.The composition of the invention is usable for treating benign prostatic hyperplasia.
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61P 13/08 - Drugs for disorders of the urinary system of the prostate
35.
Composition of acylethanolamides from olive oil fatty acids
A composition of acylethanolamides is obtained from olive oil fatty acids and is used in treating neuroinflammation. The acylethanolamide complex includes (weight percentages):
A method obtains the acylethanolamide complex and formulations contain the acylethanolamide complex.
The present invention relates to a composition of acylethanolamides obtained from olive oil fatty acids and the use thereof in treating neuroinflammation.In particular, the present invention relates to an acylethanolamide complex comprising (weight percentages):- oleoylethanolamide (OEA) C18:1 60-65%- palmitoylethanolamide (PEA) C16:0 5-20%- linoleylethanolamide (LEA) C18:2 5-20%- stearoylethanolamide (SEA) C18:0 1-2%- palmitoylethanolamide (POEA) C16:1 0.1-0.8%- myristoylethanolamide (MEA) C14:0 0.02-0.15%- mixture of glycerides 4-6%- glycerol 6-8%.Also disclosed are a method for obtaining it andformulations containing it.
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
C07C 231/02 - Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
37.
Method for the treatment of COVID-19 infections with palmitoylethanolamide
The present invention relates to a method of treating a COVID-19 infection by administering an effective amount of an endogenous compound devoid of significant toxicity. In particular, the present invention relates to a method of treating a patient affected by COVID-19 infection comprising administering an effective amount of a mixture of ultra-micronized palmitoylethanolamide and micronized palmitoylethanolamide to said patient.
The present invention relates to a method of treating a COVID-19 infection by administering an effective amount of an endogenous compound devoid of significant toxicity. In particular, the present invention relates to a method of treating a patient affected by COVID-19 infection comprising administering an effective amount of a mixture of ultra-micronized palmitoylethanolamide and micronized palmitoylethanolamide to said patient.
Described herein is a use of N-palmitoylethanolamide in the context of an antitumor therapy, in particular, a use of Palmitoylethanolamide in the prevention of colorectal carcinoma, adenomatous polyps, and/or pre-neoplastic ACF lesions. Also described herein are palmitoylethanolamide for use in the antineoplastic therapy of colorectal carcinoma, in which the palmitoylethanolamide exerts a selective antiproliferative action on tumor cells and not on healthy cells.
The present invention relates to the use of N-palmitoylethanolamide in the context of an antitumor therapy.In particular, the present invention relates to Palmitoylethanolamide for use in the prevention of colorectal carcinoma, adenomatous polyps and/or pre-neoplastic ACF lesions.Furthermore, the invention relates topalmitoylethanolamide for use in the antineoplastic therapy of colorectal carcinoma, in which saidpalmitoylethanolamide exerts a selectiveantiproliferative action on tumor cells and not on healthy cells.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical drugs; Pharmaceuticals; Pharmaceutical preparations for use in the treatment of vascular disturbances; Pharmaceutical preparations and substances with anti-inflammatory properties; Medicated creams; Medicated creams for the skin; Anti-inflammatories; Anti-inflammatory gels; Anti-inflammatory sprays.
44.
Adelmidrol For Use In Diseases Characterized By Insufficient Agonism Of PPAR-GAMMA Receptor
Described herein are pharmaceutical compositions containing Adelmidrol. In particular, the Adelmidrol is used in the treatment of diseases characterized by insufficient specific agonism of the PPAR-gamma receptor in humans or animals, more particularly in the treatment of articular chondropathies of mechanical, toxic, iatrogenic, degenerative origin, or associated with inflammatory phenomena mainly related to organs and tissues not belonging to the osteoarticular system; fibrogenesis of the articular cartilages; chronic inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis; Irritable Bowel Syndrome (IBS); diseases characterized by an abnormal fibrosis of the connective tissue, such as systemic sclerosis, particularly of the skin and lung; eye disorders characterized by angiogenesis, fibrosis, inflammation and oxidative stress.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations for the treatment of dermatological diseases and disorders; pharmaceutical preparations for the treatment of dermatological diseases and disorders for veterinary use; Medical devices for intra-articular treatment
46.
Composition of N-palmitoyl-ethanolamide and Rutin in co-micronized form
Described herein is a composition based on N-palmitoyl-ethanolamide and Rutin in co-micronized form. In particular, a composition includes a mixture of palmitoyl-ethanolamide (PEA) and Rutin in co-micronized form in which the PEA/Rutin ratio is between 10:1 and 1:1. Pharmaceutical formulations for the treatment of humans and animals are also described. The composition is useable for the treatment of diseases of arteries and arterioles.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61P 9/00 - Drugs for disorders of the cardiovascular system
The present invention relates to a composition based on N-palmitoyl-ethanolamide and Rutin in co-micronized form.In particular, the present invention relates to a composition comprising a mixture of palmitoyl-ethanolamide (PEA) and Rutin in co-micronized form in which the PEA/Rutin ratio is between 10:1 and 1:1. Pharmaceutical formulations for the treatment of humans and animals also form an object of the invention.The composition of the invention is useable for the treatment of diseases of arteries and arterioles.
A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetics; Sanitary preparations for toiletry purposes; Non-medicated cosmetics and toiletry preparations; Nasal cleaning preparations for personal sanitary purposes. Pharmaceuticals; Nasal sprays for medical purposes; Nasal spray preparations; Decongestant nasal sprays; Dietetic substances adapted for medical use; Disinfectants; Infant formula.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetics; Sanitary preparations for toiletry purposes; Non-medicated cosmetics and toiletry preparations; Oral hygiene preparations; Cosmetic preparations for the care of mouth and teeth. Pharmaceuticals; Medicated mouth spray; Dietetic substances adapted for medical use; Disinfectants; Infant formula.
51.
Use of a combination of Adelmidrol and hyaluronic acid in the treatment of pain caused by osteoarthritis and epithelial dysfunctions
Described herein is the use of Adelmidrol in the treatment of epithelial dysfunctions. In particular, described herein is Adelmidrol for use in the treatment of epithelial tissue dysfunctions in a human being or animal, wherein said Adelmidrol causes an increase of the endogenous levels of Palmitoylethanolamide without inhibiting the activity of the Palmitoylethanolamide-degrading FAAH and NAAA enzymes.
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/201 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having one or two double bonds, e.g. oleic or linoleic acid
A61K 31/421 - 1,3-Oxazoles, e.g. pemoline, trimethadione
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
31 - Agricultural products; live animals
Goods & Services
Chemical ingredients for use in the production of pharmaceutical drugs. Pharmaceutical preparations for the treatment of inflammatory disorders; Medical and surgical dressings; Dietetic foods adapted for medical use; Foodstuffs and dietetic substances for medical or veterinary purposes, Infant formula; Veterinary substances and preparations; Anti-inflammatories; Dressings, medical; Gels, creams and solutions for dermatological use. Foodstuffs and beverages for animals.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Dietetic food and substances adapted for medical use indicated in the prevention and treatment of urinary tract diseases; Dietary supplements for humans indicated in the prevention and treatment of urinary tract diseases; Pharmaceuticals and medicinal substances for humans indicated in the prevention and treatment of urinary tract diseases; Disinfectant soap; Medicated and sanitising soaps and detergents.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Syringes pre-filled with medical preparations for intratendinous infiltration, for humans; Medical preparations for humans for the prevention and treatment of inflammatory diseases of the musculoskeletal system and of the tendons; Dietary supplements and dietetic preparations for humans for the prevention and treatment of diseases of the musculoskeletal system and of the tendons; Pharmaceuticals for humans for the prevention and treatment of inflammatory diseases of the musculoskeletal system and of the tendons.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Soaps; Essential oils; Antiperspirants [toiletries]; Cosmetics; Foot care cosmetics; Non-medical preparations for treating and caring for the feet, the skin and the nails. Pharmaceutical and sanitary preparations; Pharmaceuticals and natural remedies; Pharmaceutical and medical preparations for the feet, the skin and the nails; Plasters, materials for dressings; Plasters for calluses and corns; Adhesive bands for medical purposes; Materials for bandaging [dressings]; Disinfectants; Medicated toilet preparations; Antiseptic products; Fungicides. Orthopaedic apparatus and instruments, apparatus and instruments for the care of feet; Orthotic footwear; parts and fittings for orthopaedic footwear; Orthopaedic supports for feet; Foot massagers.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical preparations for preventing and treating mast cell-dependent inflammatory diseases in the colon; Medical preparations for preventing and treating mast cell-dependent inflammatory diseases in the colon; Specialist dietetic food for medical purposes, being intended for humans with mast cell-dependent inflammatory diseases in the colon; Dietary supplements and dietetic preparations for preventing and treating mast cell-dependent inflammatory diseases in the colon. Enema syringes; Enema apparatus for medical purposes; Rectal instruments; Devices and injectors for administrating drugs.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Dermocosmetics; Topical non-medical preparations for treating the skin and mucosa; Body cleaning and beauty care preparations; Cosmetics; Toiletry preparations. Special dietetic food adapted for medical use, for human use; Dietary supplements and dietetic preparations; Pharmaceuticals; Medical preparations; Non-prescription pharmaceutical preparations; Sanitary preparations for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Body creams, not for medical purposes; Soaps and gels, not for medical purposes. Dietetic food and substances adapted for medical use indicated in the prevention and treatment of inflammatory processes in the pelvic area; Dietary supplements for humans indicated in the prevention and treatment of inflammatory processes in the pelvic area; Medicated preparations and substances indicated in the prevention and treatment of inflammatory processes in the pelvic area; Disinfectant soap; Medicated and sanitising soaps and detergents. Catheters; Catheters for urological purposes; Urethral catheterization instruments; Medical and surgical catheters; Urethral syringes; Urethral probe syringes; Enema apparatus for medical purposes; Receptacles for applying medicines; Urethral probes; Urethral dilators; Urological apparatus and instruments.
59.
ADELMIDROL FOR USE IN DISEASES CHARACTERIZED BY INSUFFICIENT AGONISM OF PPAR-GAMMA RECEPTOR
The present invention relates to a pharmaceutical composition containing Adelmidrol. In particular, the present invention concerns Adelmidrol for use in the treatment of diseases characterized by insufficient specific agonism of the PPAR-gamma receptor in humans or animals, more particularly in the treatment of articular chondropathies of mechanical, toxic, iatrogenic, degenerative origin, or associated with inflammatory phenomena mainly related to organs and tissues not belonging to the osteoarticular system; fibrogenesis of the articular cartilages; chronic inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis; Irritable Bowel Syndrome (IBS); diseases characterized by an abnormal fibrosis of the connective tissue, such as systemic sclerosis, particularly of the skin and lung; eye disorders characterized by angiogenesis, fibrosis, inflammation and oxidative stress.
"ADELMIDROL FOR USE IN DISEASES CHARACTERIZED INSUFFICIENT AGONISM OF PPAR-GAMMA RECEPTOR" The present invention relates to a pharmaceutical composition containing Adelmidrol. In particular, the present invention concerns Adelmidrol for use in the treatment of diseases characterized by insufficient specific agonism of the PPAR-gamma receptor in humans or animals, more particularly in the treatment of articular chondropathies of mechanical, toxic, iatrogenic, degenerative origin, or associated with inflammatory phenomena mainly related to organs and tissues not belonging to the osteoarticular system; fibrogenesis of the articular cartilages; chronic inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis; Irritable Bowel Syndrome (IBS); diseases characterized by an abnormal fibrosis of the connective tissue, such as systemic sclerosis, particularly of the skin and lung; eye disorders characterized by angiogenesis, fibrosis, inflammation and oxidative stress.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetic moisturising and soothing preparations for skin care; Skin treatment adjuvants, not for medical purposes; Cosmetics for use on the skin; Exfoliant creams; Barrier creams; Anti-aging creams; Skin cream; Body cream; Cosmetic hand creams; Moisturising creams, lotions and gels; Creams for reducing cellulite, wrinkles and blemishes; Age spot reducing creams; Baths (Cosmetic preparations for -); Cosmetic masks; Cosmetic preparations for skincare, not for medical use; Tanning preparations and sunscreen preparations (cosmetics); Soaps; Preparations for personal hygiene or sanitary purposes; Massage gels, other than for medical purposes; Lip gloss. Pharmaceutical preparations and pharmaceutical creams for humans for use in the dermatological sector; Dermatological preparations for medical purposes; Pharmaceuticals and medical preparations for humans for skin care, for treating damaged skin, for treating and preventing diseases and dermatological diseases; Dietary supplements for dermatological purposes; Creams and gels for humans for dermatological use; Anti-dermoinfectives; Sanitary preparations for medical purposes; Antiseptics; Dressings, medical; Disinfectants for hygiene purposes; Disinfectant soap; medical soap.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetic moisturising and soothing preparations for skin care; Skin treatment adjuvants, not for medical purposes. Veterinary and pharmaceutical preparations for dermatological use; Medical devices for intra-articular treatment.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetic preparations for human use for hyperkeratosis. Topical pharmaceutical and parapharmaceutical preparations for human use for treating of hyperkeratosis.
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Ingredients for use in the preparations of cosmetics. Cosmetic skin care preparations. Ingredients for preparation of pharmaceutical preparations; Ingredients for use in the preparation of dietetic foodstuffs and dietetic supplements adapted for medical use; Pharmaceutical preparations; Dietetic foods and Dietetic supplements adapted for medical use.
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations; Dietetic food and substances for medical use; Food supplements for human use. Scientific investigations for medical purposes. Information in the medical and nutritional sectors; Medical services; Pharmacy advice.
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations; Dietetic food and substances for medical use; Food supplements for human use. Scientific investigations for medical purposes. Information in the medical and nutritional sectors; Medical services; Pharmacy advice.
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations; Dietetic food and substances adapted for medical use in the gynaecological field; Food supplements for human use. Scientific investigations for medical purposes. Information in the medical and nutritional sectors; Medical services; Pharmacy advice.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Soaps and cosmetic preparations for use in the urological-andrological field. Pharmaceutical preparations for use in the urological-andrological field; Sanitary preparations for use in the urological-andrological field. Scientific investigations for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Composition of active ingredients for use in the preparation of cosmetic products. Composition of active ingredients for use in the preparation of pharmaceutical products and foodstuffs, dietetic substances and food supplements adapted for medical use. Scientific investigations for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations for use in the urological field; Sanitary preparations for use in the urological field. Medical apparatus and instruments for urological use. Scientific investigations for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Bleaching preparations and other substances for laundry use; Cleaning, polishing, scouring and abrasive preparations; Soaps; Perfumery, essential oils, cosmetics, hair lotions; Dentifrices; Antiperspirants [toiletries]; Shampoos. Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic substances adapted for medical use; Plasters, materials for dressings; Materials for stopping teeth and dental wax; Disinfectants. Scientific and technological services and research and design relating thereto; Industrial analysis and research services.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions, dentifrices; Antiperspirants [toiletries]; Shampoos. Pharmaceutical, veterinary and sanitary preparations; dietetic substances for medical use, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax, disinfectants; preparations for destroying vermin; fungicides, herbicides. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; orthopedic articles; suture materials.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Bleaching preparations and other substances for laundry use; Cleaning, polishing, scouring and abrasive preparations; Soaps; Perfumery, essential oils, cosmetics, hair lotions, dentifrices; Antiperspirants [toiletries]; Shampoos. Pharmaceutical preparations for the treatment of balanitis. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; Orthopedic articles; Suture materials.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Bleaching preparations and other substances for laundry use; Cleaning, polishing, scouring and abrasive preparations; Soaps; Perfumery, essential oils, cosmetics, hair lotions, dentifrices; Antiperspirants [toiletries]; Shampoos. Pharmaceutical and veterinary preparations, except for therapeutics for treating anemia; Sanitary preparations; Dietetic substances adapted for medical use, food for babies; Plasters, materials for dressings; Material for stopping teeth, dental wax, disinfectants; Preparations for destroying vermin; Fungicides, herbicides.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Bleaching preparations and other substances for laundry use; Cleaning, polishing, scouring and abrasive preparations; Soaps; Perfumery, essential oils, cosmetics, hair lotions; Dentifrices; antiperspirants [toiletries]; shampoos. Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic substances adapted for medical use, food for babies; Plasters, materials for dressings; Materials for stopping teeth and dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; eyepatches for medical purposes. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; Orthopedic articles; Suture materials.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Bleaching preparations and other substances for laundry use; Cleaning, polishing, scouring and abrasive preparations; Soaps; Perfumery, essential oils, cosmetics, hair lotions; Dentifrices; Antiperspirants [toiletries]; Shampoos. Sanitary preparations for medical purposes; Dietetic substances adapted for medical use, food for babies; Plasters, materials for dressings; Materials for stopping teeth and dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides. Scientific and technological services and research and design relating thereto; Scientific and technological services and research and design relating thereto.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Non-medicated preparations for topical application; cosmetic products. Pharmaceutical and veterinary preparations; sanitary preparations for medical purposes; dietary substances for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Cosmetics for regulating the production of sebum and the hypersensitivity of tissue. Dermatological pharmaceuticals for regulating the production of sebum and the hypersensitivity of tissue. Information and consultancy in the therapeutic dermatological and dermo-cosmetic fields; medical, hygienic and beauty care.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions; dentifrices; antiperspirants [toiletries]; shampoos. Pharmaceutical, veterinary and sanitary preparations for medical purposes; dietetical substances for medical use, foodstuffs for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; contact lenses (solutions for use with-); eyepatches for medical purposes. Medical services; veterinary services; hygiene and beauty care for people or animals; agriculture, horticulture and forestry services.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions; dentifrices; Antiperspirants [toiletries]; Shampoos. Pharmaceutical, veterinary and sanitary preparations for medical purposes; dietetical substances for medical use, foodstuffs for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; Eyepatches for medical purposes. Medical services; veterinary services; hygiene and beauty care for people or animals; agriculture, horticulture and forestry services.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions; dentifrices; antiperspirants [toiletries]; shampoos. Pharmaceutical, veterinary and sanitary preparations for medical purposes; dietetical substances for medical use, foodstuffs for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; eyepatches for medical purposes. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; orthopedic articles; materials for podiatric orthoses; suture materials.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions; dentifrices; antiperspirants [toiletries]; shampoos. Dietetic foodstuffs for special medical purposes, namely as nutritional supplement for normalizing hyperreactivity of mast cells. Providing information in the field of nutrition; medical, hygienic and beauty care; consultancy in the field of pharmaceuticals.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions; dentifrices; antiperspirants [toiletries]; shampoos. Pharmaceutical and veterinary preparations; sanitary preparations for medical purposes; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; eyepatches for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetic preparations for male genital area. Products for phimosis and paraphimosis; products for topical use designed to help control mucocutaneous hyper-reactivity of male genital area, all products for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumery, essential oils, cosmetics, hair lotions; dentifrices; Antiperspirants [toiletries]; Shampoos. Pharmaceutical and veterinary preparations; sanitary preparations for medical purposes; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; Eyepatches for medical purposes.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Soaps, essential oils, cosmetics, cosmetics for foot care. Pharmaceutical and sanitary preparations for foot care, for nail care; plasters, materials for dressings; disinfectants; fungicides.