A drug infusion system comprises a plurality of infusion pumps including a first infusion pump and a second infusion pump and a computing device. The computing device comprises a non-transitory computer-readable storage medium and a processor coupled to the non-transitory computer-readable storage medium. The processor is configured to control a plurality of modules to establish a relay sequence of the plurality of infusion pumps to sequentially deliver drugs associated with each of the plurality of infusion pumps to a patient, in response to detecting that the first infusion pump completes an infusion, automatically transfer infusion status information of the first infusion pump to the second infusion pump in the relay sequence, activate the second infusion pump to start infusing in accordance with the relay sequence, remove the first infusion pump from the relay sequence, and retain operational parameters of the first infusion pump.
A peritoneal dialysis (“PD”) system having an ultrafilter is disclosed herein. In one example, the PD system includes a housing and a PD fluid pump. The PD system also includes a filter comprising an outer chamber, a central portion, a membrane, an inlet connected to the outer chamber, an outlet, a first venting port connected to the outer chamber, and a second venting port connected to the central portion. The first venting port has a valve preventing air flow into the filter via the first venting port. The PD system further includes a pressure sensor and a control unit configured to control the PD fluid pump. The control unit is further configured to determine a pressure inside the filter based on an output from the pressure sensor and determine an integrity status of the membrane based on the pressure inside the filter.
A medical device hub power management system, method, and apparatus are disclosed. An example infusion pump docking apparatus of a hub connectivity station includes a housing and a device connector assembly. The device connector assembly includes a mounting bracket fixedly connected to an interior surface of the housing forming a mounting cavity between the mounting bracket and the housing. The device connector assembly also includes a device connector to provide electrical connection between the docking apparatus and a medical device, where the device connector is positioned in the mounting cavity. The device connector assembly also includes a spring positioned in the mounting cavity between a flange surface of the mounting bracket and a rear surface of the device connector. The spring is deformable during connection of the medical device to the device connector to allow movement of the device connector within the mounting cavity.
A peritoneal dialysis ("PD") system includes a PD fluid pump configured to pump PD fluid along a line under negative pressure and to create a negative pressure profile having a maximum negative pressure and a minimum negative pressure; a pressure sensor positioned and arranged to sense the negative pressure profile and to produce an output indicative of the negative pressure profile including a maximum negative pressure output and a minimum negative pressure output; and a control unit configured to analyze the output indicative of the negative pressure profile and to determine that an occlusion in the line has occurred if both the maximum negative pressure output and the minimum negative pressure output change by at or more than a set pressure delta, wherein the set pressure delta is optionally the same pressure delta for the maximum negative pressure output and the minimum negative pressure output.
Provided herein is a peritoneal dialysis ("PD") system comprising a housing and one or more doors comprising elastomeric properties. Each of the one or more doors comprises one or more features configured to couple to one or more features of the housing. Further, each door includes one or more inserts molded between two layers of elastomeric material where the features are coupled to. The doors are configured to cover and thermally insulate one or more PD fluid lines when in a closed configuration. The doors are also configured to transition to an open configuration to provide access to one or more PD fluid lines for treatment.
Provided herein is a peritoneal dialysis (“PD”) system comprising a housing and one or more doors comprising elastomeric properties. Each of the one or more doors comprises one or more features configured to couple to one or more features of the housing. Further, each door includes one or more inserts molded between two layers of elastomeric material where the features are coupled to. The doors are configured to cover and thermally insulate one or more PD fluid lines when in a closed configuration. The doors are also configured to transition to an open configuration to provide access to one or more PD fluid lines for treatment.
A system, method, and apparatus are disclosed for determining positions of medical devices within a hub, which comprises a number of apparatuses that are linked together in a stacked configuration. A medical device hub includes a connectivity apparatus that is communicatively coupled to a medical network and/or a monitoring device. Additionally, the medical device hub includes one or more docking apparatuses. Each docking apparatus can accommodate two or more infusion pumps. The number of docking apparatuses used in the medical device hub depends on the number of infusion pumps needed for a patient treatment. The medical device hub enables multiple docking apparatuses to be stacked as needed while enabling the infusion pumps to be operated independently and removed from the medical device hub as needed, even during a treatment without interruption. Such a configuration provides a scalable, flexible, and adaptable system that aggregates infusion pumps into a relatively small footprint.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
This invention provides a system adapted to be worn entirely on a patient's body for measuring a pulse oximetry (SpO2) parameter and an electrocardiogram (ECG) parameter. The system includes first and second ECG electrodes that adhere to a patient's chest. The system further includes a flexible component to transmit the ECG parameter from the first and second ECG electrodes to an electronics module. The electronics module includes an electronic circuit, a microprocessor, a temperature sensor, and a wireless transmitter. The system further includes a pulse oximetry system for measuring the pulse oximetry (SpO2) parameter.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
The present invention relates to a novel solid pharmaceutical preparation for peritoneal dialysis comprising nucleating particles of sodium chloride coated with plurality of layers, wherein the plurality of layers comprises, a first layer (A) of sodium bicarbonate, second layer (B) comprising sodium chloride and dextrose, third layer (C) comprising the electrolytes calcium chloride and magnesium chloride, and the fourth outmost layer (D) comprising sodium lactate. The present invention also relates to a process for producing the novel solid pharmaceutical preparation.
A peritoneal dialysis ("PD") system having an ultrafilter is disclosed herein. In one example, the PD system includes a housing and a PD fluid pump. The PD system also includes a filter comprising an outer chamber, a central portion, a membrane, an inlet connected to the outer chamber, an outlet, a first venting port connected to the outer chamber, and a second venting port connected to the central portion. The first venting port has a valve preventing air flow into the filter via the first venting port. The PD system further includes a pressure sensor and a control unit configured to control the PD fluid pump. The control unit is further configured to determine a pressure inside the filter based on an output from the pressure sensor and determine an integrity status of the membrane based on the pressure inside the filter.
A system, method, and apparatus are disclosed for determining positions of medical devices within a hub, which comprises a number of apparatuses that are linked together in a stacked configuration. A medical device hub includes a connectivity apparatus that is communicatively coupled to a medical network and/or a monitoring device. Additionally, the medical device hub includes one or more docking apparatuses. Each docking apparatus can accommodate two or more infusion pumps. The number of docking apparatuses used in the medical device hub depends on the number of infusion pumps needed for a patient treatment. The medical device hub enables multiple docking apparatuses to be stacked as needed while enabling the infusion pumps to be operated independently and removed from the medical device hub as needed, even during a treatment without interruption. Such a configuration provides a scalable, flexible, and adaptable system that aggregates infusion pumps into a relatively small footprint.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
12.
MEDICAL DEVICE HUB CONNECTION SYSTEM, METHOD, AND APPARATUS
A medical device hub power management system, method, and apparatus are disclosed. An example infusion pump docking apparatus of a hub connectivity station includes a housing and a device connector assembly. The device connector assembly includes a mounting bracket fixedly connected to an interior surface of the housing forming a mounting cavity between the mounting bracket and the housing. The device connector assembly also includes a device connector to provide electrical connection between the docking apparatus and a medical device, where the device connector is positioned in the mounting cavity. The device connector assembly also includes a spring positioned in the mounting cavity between a flange surface of the mounting bracket and a rear surface of the device connector. The spring is deformable during connection of the medical device to the device connector to allow movement of the device connector within the mounting cavity.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A peritoneal dialysis (“PD”) system includes a PD fluid pump configured to pump PD fluid along a line under negative pressure and to create a negative pressure profile having a maximum negative pressure and a minimum negative pressure; a pressure sensor positioned and arranged to sense the negative pressure profile and to produce an output indicative of the negative pressure profile including a maximum negative pressure output and a minimum negative pressure output; and a control unit configured to analyze the output indicative of the negative pressure profile and to determine that an occlusion in the line has occurred if both the maximum negative pressure output and the minimum negative pressure output change by at or more than a set pressure delta, wherein the set pressure delta is optionally the same pressure delta for the maximum negative pressure output and the minimum negative pressure output.
A peritoneal dialysis (“PD”) system includes a PD fluid pump including a reciprocating member having a home position; at least one pressure sensor positioned and arranged to sense pressure PD fluid pumped by the PD fluid pump; and a control unit configured to control the PD fluid pump and to take PD fluid pressure readings from the at least one pressure sensor, the control unit further configured to use the PD fluid pressure readings to determine when the reciprocating member is in the home position, and to stop the PD fluid pump when the reciprocating member is in the home position.
An infusion pump for detecting an occlusion is provided. The memory stores instructions that cause the one or more processors to input data into a trained neural network, and generate an alert when the trained neural network outputs an amount of occlusion flags above a predetermined threshold.
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
The present invention provides a hemostatic porous composite sponge comprising:
i) a matrix of a biomaterial; and
ii) one hydrophilic polymeric component comprising reactive groups
wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that
said polymeric component is coated onto a surface of said matrix of a biomaterial, or
said matrix is impregnated with said polymeric material, or
both.
A61L 15/18 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
A61L 15/26 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bondsDerivatives thereof
A61L 15/32 - Proteins, polypeptidesDegradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
A61L 15/42 - Use of materials characterised by their function or physical properties
A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
18.
AUTOMATED FLUID DISPENSER WITH DRIVER AND DISPOSABLE PROBE
An infusion pump for detecting an occlusion is provided. The memory stores instructions that cause the one or more processors to input data into a trained neural network, and generate an alert when the trained neural network outputs an amount of occlusion flags above a predetermined threshold.
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
20.
DIALYSIS SYSTEM HAVING PUMP ACTUATOR POSITION DETECTION
A peritoneal dialysis ("PD") system includes a PD fluid pump including a reciprocating member having a home position; at least one pressure sensor positioned and arranged to sense pressure PD fluid pumped by the PD fluid pump; and a control unit configured to control the PD fluid pump and to take PD fluid pressure readings from the at least one pressure sensor, the control unit further configured to use the PD fluid pressure readings to determine when the reciprocating member is in the home position, and to stop the PD fluid pump when the reciprocating member is in the home position.
B01F 25/452 - Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
B01F 23/40 - Mixing liquids with liquidsEmulsifying
B01F 23/45 - Mixing liquids with liquidsEmulsifying using flow mixing
B01F 33/81 - Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
B01F 101/36 - Mixing of ingredients for adhesives or gluesMixing adhesives and gas
22.
PACKAGED, SEALED CONTAINER SYSTEM FOR STABLE STORAGE OF AN OXYGEN SENSITIVE PHARMACEUTICAL FORMULATION
A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
B65D 75/28 - Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
B65D 81/26 - Adaptations for preventing deterioration or decay of contentsApplications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, fluids, e.g. exuded by contentsApplications of corrosion inhibitors or desiccators
23.
DIALYSIS SYSTEM INCLUDING A WATER TREATMENT DEVICE
A dialysis system is disclosed. An example dialysis system includes a water treatment device configured to provide purified water and a dialysate production unit including a processor, a dialysate holding tank, and a dialysate mixing pump connected to a source of concentrate. The dialysate production unit is configured to prepare dialysate using the purified water provided by the water treatment device. The processor of the dialysate production unit is configured to receive an indication that a batch of dialysate is needed, cause the water treatment unit to begin providing the purified water, cause the dialysate mixing pump to pump a concentrate from the source of concentrate for mixing with the purified water to form the dialysate for storage in the dialysate holding tank, and after the batch of the dialysate has been stored to the dialysate holding tank, cause the water treatment unit to stop providing the purified water.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 5/44 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for cooling or heating the devices or media
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
24.
METHODS AND APPARATUSES USING UREA PERMSELECTIVE DIFFUSION THROUGH CHARGED MEMBRANES
Systems and apparatuses for regenerating used dialysis fluid are described herein. In an embodiment, a regenerative dialysis fluid system includes a dialysis unit configured to generate used dialysis fluid including urea and a urea separation unit configured to separate at least a portion of the urea from the used dialysis fluid into a secondary fluid. The urea separation unit includes a membrane separating a dialysis fluid chamber from a urea chamber. The membrane includes at least one of a positive charge to prevent positive ions from transporting across the membrane and a negative charge to prevent negative ions from transporting across the membrane.
An apparatus for breaking a frangible engaged with a medical catheter is provided. The medical catheter includes a first catheter section and a second catheter section which are connected with each other via a connector having a first flange, where the frangible is engaged with the second catheter section. The apparatus includes a first component having a first end and a second end opposite to the first end. The first component includes: a first groove formed on top of the first component and extending along a longitudinal direction of the first component from the first end of the first component to the second end of the first component, where the first groove is configured for receiving the first catheter section and a part of the second catheter section; a first slot formed perpendicular to and recessed from the first groove, wherein the first slot is positioned close to the first end of the first component and configured for receiving the first flange; and a first catheter clamping bulge protruding from a surface of the first groove, where the first catheter clamping bulge is positioned closer to the first end of the first component than the first slot.
A renal therapy system is disclosed. In an example, the renal therapy system includes a home renal therapy machine that stores, to a log file, blood pressure measurements, heart rate measurements, and blood glucose measurements. The system also includes a server that receives the log file from the home renal therapy machine. The server receives the log file for displaying the blood pressure measurements, the heart rate measurements, and the blood glucose measurements for clinician review.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
A medical fluid system includes a medical fluid pump configured to pump a medical fluid; a tube through which medical fluid pumped by the medical fluid pump flows; a pinch valve positioned and arranged to occlude the tube to prevent medical fluid from flowing through the tube, the pinch valve including a motor; a current sensor positioned and arranged to sense a current drawn by the motor of the pinch valve; and a control unit operable with the current sensor to monitor the current drawn by the motor while the motor is causing the pinch valve to occlude the tube, the control unit configured to stop the motor when the monitored current indicates an occlusion of the tube.
An apparatus for breaking a frangible is provided. The frangible is engaged with a medical catheter. The apparatus includes: an elongated handle and a clamping portion; the elongated handle is configured for being gripped by a hand of an operator; the clamping portion is arranged at a distal end of the elongated handle and includes two clamping arms protruding away from the elongated handle in a longitudinal direction of the elongated handle; the two clamping arms are spaced apart from and parallel to each other to form a trench for partially receiving a portion of the medical catheter where a frangible end of the frangible is located; and the two clamping arms are configured for applying a breaking force on the frangible end of the frangible when the elongated handle is rotated around a longitudinal axis of the elongated handle by the operator.
Example systems, methods, and apparatus are disclosed herein for dynamically assigning unique message identifiers for devices in a CAN bus network. The example systems, methods, and apparatus are configured to allow devices, such as infusion pumps, to propose and acquire unique IDs within a CAN bus network. The example systems, methods, and apparatus are configured to use the exchange of information between devices in a CAN bus network to prevent duplicate unique IDs, and to allow for simultaneous unique IDs to be acquired by devices. The disclosed systems, methods, and apparatus prevent human programming errors by minimizing the need for extensive user interaction with devices joining a CAN bus network and need to know and select node IDs during installation. The disclosed systems, methods, and apparatus increase network efficiency and prevent programming errors that might result in patient discomfort or injury in healthcare settings, such as networks including infusion pumps.
An aim of the disclosure is to control a water purification apparatus that uses reverse osmosis (RO) to consistently produce permeate water with a desired quality. The permeability of a RO membrane varies with a temperature of feed water. Hot water has a lower viscosity and a higher diffusion rate than cold water. The pores of the RO membrane expand at higher temperatures, causing a higher flow through the RO membrane from a feed to a product side. Consequently, higher temperatures cause higher permeate flow over the RO membrane and increased salt passage through the RO membrane. In order to improve the salt rejection rate, more permeate water needs to pass through the RO membrane to dilute the salts. This is achieved by increasing feed side pressure when the RO membrane temperature increases, thereby causing an increased flow of permeate water.
Retainer apparatus may be configured to retain a cable having a connector operably coupled to a device The retainer apparatus may include a mounting portion configured to be selectively coupled to the device and an insertion portion coupled to the mounting portion. The insertion portion may define a channel configured to receive the connector of the cable and to restrict the connector of the cable from moving away from the device when the connector is operably coupled to the device and received in the channel and the mounting portion is coupled to the device.
A peritoneal dialysis system comprises a cycler including a peristaltic pump actuator, and a weigh scale; a disposable set including a peristaltic pump tube operable with the peristaltic pump actuator, a patient line in fluid communication with the peristaltic pump tube, and a heating container in operable communication with the weigh scale; and a control unit configured to cause (i) the peristaltic pump actuator to operate at a rotational speed to cause an amount of fluid to enter the heating container, (ii) weigh the amount of fluid, and (iii) determine at least one of a mass rate or volume rate for the rotational speed.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
33.
DYNAMIC ASSIGNMENT OF UNIQUE CAN (CONTROLLER AREA NETWORK) MESSAGE IDENTIFIERS FOR DEVICES
Example systems, methods, and apparatus are disclosed herein for dynamically assigning unique message identifiers for devices in a CAN bus network. The example systems, methods, and apparatus are configured to allow devices, such as infusion pumps, to propose and acquire unique IDs within a CAN bus network. The example systems, methods, and apparatus are configured to use the exchange of information between devices in a CAN bus network to prevent duplicate unique IDs, and to allow for simultaneous unique IDs to be acquired by devices. The disclosed systems, methods, and apparatus prevent human programming errors by minimizing the need for extensive user interaction with devices joining a CAN bus network and need to know and select node IDs during installation. The disclosed systems, methods, and apparatus increase network efficiency and prevent programming errors that might result in patient discomfort or injury in healthcare settings, such as networks including infusion pumps.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
34.
MEDICAL DEVICE HUB POWER MANAGEMENT SYSTEM, METHOD, AND APPARATUS
A medical device hub power management system, method, and apparatus are disclosed. An example hub connectivity station includes a connectivity stage configured to provide a data connection with an external network. The hub connectivity station also includes at least one docking apparatus configured to connect to at least one medical device. The docking apparatuses are connected to the connectivity station in a stacked arrangement. The docking apparatuses and connectivity stage include power and data connectors to enable data and power to be provided through the hub connectivity station. To prevent electrical shock, a top power connector of each docking apparatus is disconnected from power when that docking apparatus is not connected to another docking apparatus or the connectivity stage. Power is provided to the top power connector after detecting another docking apparatus or the connectivity stage is connected to the top of the docking apparatus.
A drug infusion system comprises a plurality of infusion pumps including a first infusion pump and a second infusion pump and a computing device. The computing device comprises a non-transitory computer-readable storage medium and a processor coupled to the non-transitory computer-readable storage medium. The processor is configured to control a plurality of modules to establish a relay sequence of the plurality of infusion pumps to sequentially deliver drugs associated with each of the plurality of infusion pumps to a patient, in response to detecting that the first infusion pump completes an infusion, automatically transfer infusion status information of the first infusion pump to the second infusion pump in the relay sequence, activate the second infusion pump to start infusing in accordance with the relay sequence, remove the first infusion pump from the relay sequence, and retain operational parameters of the first infusion pump.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
This application provides a male connector for a peritoneal tubing carried by a patient practicing ambulatory peritoneal dialysis, a cap, and a female connector. The male connector includes: a hollow main body having a first end and a second end, where the hollow main body is configured to be sealingly connected with the peritoneal tubing at the first end, where the hollow main body includes an engaging portion, a base, and a flip snap. The engaging portion is at the second end of the hollow main body, and the engaging portion includes a conic outer surface having a diameter reducing toward the second end; the base is positioned between the first end and the engaging portion; and the flip snap is pivotably connected to the base, where the flip snap is configured to pivot relative to the base between an idle position where the flip snap engages with the base, and a locking position where the flip snap can releasably engage with a cap or a female connector.
A medical device hub power management system and apparatus are disclosed. An example hub connectivity station (100) includes a connectivity stage (104) configured to provide a data connection with an external network. The hub connectivity station also includes at least one docking apparatus (106) configured to connect to at least one medical device. The docking apparatuses are connected to the connectivity station in a stacked arrangement. The docking apparatuses and connectivity stage include power and data connectors to enable data and power to be provided through the hub connectivity station. To prevent electrical shock, a top power connector of each docking apparatus is disconnected from power when that docking apparatus is not connected to another docking apparatus or the connectivity stage. Power is provided to the top power connector after detecting another docking apparatus or the connectivity stage is connected to the top of the docking apparatus.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
38.
Perforating connector for medical fluid containers
A perforating connector assembly including a valve; and a perforating connector comprising a perforator accepted by the valve, the perforator including a spiked end and a lever, the lever including a projection, a shell extending around the perforator and the valve, the shell including a pre-activation opening and a post-activation opening, a spring held compressed during pre-activation by a tab of the lever being located within the pre-activation opening, and an actuator slidingly engaged to the shell, the actuator including a projection, the actuator translatable by a user so that the projection becomes aligned with the tab located within the opening, wherein the user is able to push the projection into the pre-activation opening to disengage the tab from the opening, and wherein the spring is able to decompress and translate the perforator so that the medical fluid container is accessed and the tab becomes located within the post-activation opening.
A peritoneal dialysis (“PD”) system includes a patient line connector having a patient line recirculation cap to enable PD fluid to be recirculated through the patient line connector when sealingly capped by the patient line recirculation cap. The PD system also includes a drain line connector having a drain line recirculation cap enabling PD fluid to be recirculated through the drain line connector when sealingly capped by the drain line recirculation cap. The PD system further includes a dialysis fluid inline heater in fluid communication with a PD fluid side of at least one fixed volume chamber and a control unit configured to run a heat cleaning sequence after a PD treatment. For the heat cleaning sequence, the patient line connector is capped by the patient line recirculation cap and the drain line connector is capped by the drain line recirculation cap.
Symmetric key exchange via TLS on CAN bus interface for multiple devices. The key exchange is configured to elect a master PCA pump for a CAN bus network and prevent two PCA pumps from being master. Upon joining the CAN bus network PCA pumps exchange their MAC IDs with the PCA pumps in the CAN bus network. Once a bootstrap timeout ends, each PCA pump compares all MAC IDs to determine if it should advance to the voting stage. If the PCA pump has the lowest MAC ID, the PCA pump enters the voting stage. During the voting stage, the PCA pump sends master requests prompts to all the PCA pumps in the network. If the PCA pump's internal vote counter reaches a count of three the PCA pump becomes key master.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
Symmetric key exchange via TLS on CAN bus interface for multiple devices. The key exchange is configured to elect a master PCA pump for a CAN bus network and prevent two PCA pumps from being master. Upon joining the CAN bus network PCA pumps exchange their MAC IDs with the PCA pumps in the CAN bus network. Once a bootstrap timeout ends, each PCA pump compares all MAC IDs to determine if it should advance to the voting stage. If the PCA pump has the lowest MAC ID, the PCA pump enters the voting stage. During the voting stage, the PCA pump sends master requests prompts to all the PCA pumps in the network. If the PCA pump's internal vote counter reaches a count of three the PCA pump becomes key master.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
42.
MEDICAL DEVICE SPEECH AND GESTURE CONTROL METHODS, APPARATUSES, AND SYSTEM
Methods, apparatuses, and systems for medical device speech and gesture control are disclosed herein. An example apparatus includes an audio interface that converts received audio into text, for example. The audio interface uses a current operating statue of the medical device to determine a command from the text and whether the command is enabled. When the command is enabled, the audio interface transmits a command message to a response manager, which converts the command to a medical device command signal. The response manager then transmits the medical device command signal to a control engine of the medical device to change how the medical device is operating based on the received audio. The same medical device command signal is used for similar touch and/or gesture inputs such that the control engine does not need to be modified based on which input modalities are implemented on the medical device.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A peritoneal dialysis ("PD") system includes a plurality of PD fluid components, a reusable PD fluid line selectively fluidly communicating with the PD fluid components, a source of PD fluid selectively fluidly communicating with the reusable PD fluid line, a source of anti-scaling fluid selectively fluidly communicating with the reusable PD fluid line, and a control unit configured to (i) operate the plurality of PD fluid components during treatment using PD fluid from the source heated to a treatment temperature, and (ii) circulate unused PD fluid heated to a disinfection temperature in combination with anti-scaling fluid from the source of anti-scaling fluid after treatment for disinfecting the plurality of PD fluid components and the reusable PD fluid line, the anti-scaling fluid provided in an amount configured to lower the pH of the unused PD fluid to a level below which precipitates are formed and above which the pH causes disinfection.
An airtrap for a medical or physiological fluid in one embodiment includes a conical housing having a radius that increases from its top to its bottom when the housing is positioned for operation; a medical or physiological fluid inlet located at an upper portion of the conical housing; a medical or physiological fluid outlet located at a lower portion of the conical housing, the inlet and the outlet positioned and arranged so that medical or physiological fluid spirals in an increasing arc around an inside of the conical housing downwardly from the inlet to the outlet; and a gas collection area located at an upper portion of the conical housing. In another embodiment, the airtrap is shaped like a seahorse having a head section and a tail section. Any of the airtraps herein may be used for example in blood sets, peritoneal dialysis cassette tubing, and drug delivery sets.
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 5/36 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body
A61M 5/38 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body using hydrophilic or hydrophobic filters
A dialysis system includes a source of water; a concentrate for mixing with the water a disposable set including a pumping portion, a water line in fluid including a filter for filtering the water, a concentrate line in fluid communication with the source of water and the pumping portion; and a medical fluid delivery machine including a pump actuator operable with the pumping portion, a pressure sensor, and a control unit programmed to cause (i) the pump actuator to pump water to wet a membrane of the filter, thereafter remove at least some of the water from the filter, and pressurize a portion of the water line leading from the pumping portion to the filter, (ii) the pressure sensor to sense pressure in the pressurized portion of the water line, and (iii) an analysis of the sensed pressure to be performed to evaluate the integrity of the filter.
A flexible multi-chamber bag for storing and reconstituting parenteral nutrition solutions is disclosed. The flexible multi-chamber bag comprises a first peelably sealing wall and a second peelably sealing wall between the two polymer films extending from the top edge to the bottom edge and separating the first bag into a first chamber between the first peelably sealing wall and the second peelably sealing wall, a first space between the left edge and the first peelably sealing wall, a second space between the second peelably sealing wall and the right edge; a third peelably sealing wall extending from the left edge to the first peelably sealing wall to separate the first space to form a third chamber and a fourth chamber; and a fourth peelably sealing wall extending from the right edge to the second peelably sealing wall to separate the second space to form a second chamber and a fifth chamber.
A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
B65D 75/28 - Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
B65D 81/26 - Adaptations for preventing deterioration or decay of contentsApplications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, fluids, e.g. exuded by contentsApplications of corrosion inhibitors or desiccators
A medical fluid delivery machine includes a medical fluid pump, at least one of a positive air pressure source or a negative air pressure source for supplying positive or negative pressure air, a pneumatic manifold including an air passageway, a pneumatic valve, and a gasket. The pneumatic valve includes a pneumatic port having a mating threaded portion and a smooth portion.
F04B 7/00 - Piston machines or pumps characterised by having positively-driven valving
F04B 43/02 - Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
F04B 43/14 - Machines, pumps, or pumping installations having flexible working members having peristaltic action having plate-like flexible members
F04B 49/00 - Control of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for in, or of interest apart from, groups
F04B 53/22 - Arrangements for enabling ready assembly or disassembly
F16L 15/00 - Screw-threaded jointsForms of screw-threads for such joints
The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.
A system, apparatuses, and methods are disclosed that provide pump interconnectivity for pain medication therapies. In an example embodiment, a system includes a patient-controlled analgesia (“PCA”) pump, an infusion pump, and a hub device configured to connect to the PCA pump and the infusion pump. The hub device is configured to determine the PCA pump and the infusion pump are both communicatively connected to the hub device, enable the PCA pump and the infusion pump to communicate with each other for a pain medication therapy, and enable the infusion pump to deliver the fluid to the patient when the infusion pump detects a period between periodic PCA pump boluses.
A peritoneal dialysis system includes a dialysis fluid pump including a pump actuator and a dialysis fluid contacting portion actuated by the pump actuator, a fresh dialysis fluid valve located upstream of the pump and including a fresh valve actuator and a dialysis fluid contacting portion actuated by the fresh valve actuator, a patient line valve located downstream of the pump and including a patient line valve actuator and a dialysis fluid contacting portion actuated by the patient line valve actuator, a drain valve positioned and arranged to receive used dialysis fluid from the patient and including a drain valve actuator and a dialysis fluid contacting portion, a patient line extending from the drain valve, and a fluid loop including dialysis fluid contacting portions of the pump, the fresh dialysis fluid valve, the patient line valve, and the drain valve. The patient line extends from the fluid loop.
Disclosed herein is a water purification apparatus capable of being cleaned at a point of care, and methods for cleaning the water purification apparatus at the point of care. The water purification apparatus and the methods provide an efficient use of a heater for heat disinfection the water purification apparatus, e.g. by recirculating heated fluid to further heat the fluid. Several different cleaning programs are provided that may be utilized for cleaning different parts of the water purification apparatus.
B01D 61/48 - Apparatus therefor having one or more compartments filled with ion-exchange material
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/28 - Treatment of water, waste water, or sewage by sorption
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
C02F 101/12 - Halogens or halogen-containing compounds
A disposable set for a peritoneal dialysis (“PD”) treatment includes a fresh PD fluid pumping portion; a used PD fluid pumping portion; a reusable tubing section including the fresh PD fluid pumping portion and a one-way valve, the reusable tubing section terminating at a first connector; and a disposable tubing section including the used PD fluid pumping portion and terminating at a second connector, the second connector configured to be connected to the first connector to form the disposable set for use in the PD treatment.
Ultrafiltration (UF) is monitored in a weight-based system for extracorporeal blood treatment. The system comprises a container holding a fluid that is pumped to or from a dialyzer by a pump. The container is intermittently refilled or drained by an adjustment arrangement during a level adjustment period (LAP). A scale measures the weight of the container. A monitoring device is operated to determine, before and after the LAP while the adjustment arrangement is deactivated and the pump is operated at a known setting, first and second values of a parameter of the pump based on a weight signal from the scale. The parameter may be flow rate or stroke volume. The monitoring device estimates a time profile for the parameter during the LAP based on the first and second values and determines the UF parameter based on the time profile.
A flexible plug for a medical fluid comprises a sealing member including a flexible cylindrical section that extends to a head; a rigid member holder secured to the sealing member; and a rigid sealing cap including a wall defining an opening, the head of the sealing member sealed within the opening to prevent the flow of medical fluid through the flexible plug. The flexible plug is sealed, e.g., solvent bonded, within a port tube, sleeve port or a Y-connector to form a flexible plug assembly. The user grasps and twists or torques the rigid member holder and the rigid sealing cap through the port tube, sleeve port or a Y-connector to unseal the head from the opening to allow the flow of medical fluid through the flexible plug. A method of manufacturing the flexible plug and associated assembly is also disclosed.
A peritoneal dialysis (“PD”) system includes a disposable set including a pump chamber having a flexible sheet, one side of the flexible sheet positioned and arranged during operation to receive pneumatic pressure; and a cycler including at least one source of positive and negative pneumatic pressure for delivering pneumatic pressure to the pump chamber, an air flow sensor, a pneumatic pressure sensor, a temperature sensor, a plurality of fluid valves, and a control unit configured to integrate outputs from the air flow sensor, the pneumatic pressure sensor and the temperature sensor over time to determine an amount of fresh or used PD fluid discharged from the pump chamber under positive pneumatic pressure and via an open one of the plurality of fluid valves.
Methods, systems, and apparatuses for integrating medical device data are disclosed. In an example embodiment, an integration engine receives infusion therapy progress data from an infusion pump related to a patient identifier and receives renal failure therapy progress data from a renal failure therapy machine related to the same patient identifier. The integration engine determines fluid balance data based on a difference between at least some of the infusion therapy progress data and at least some of the renal failure therapy progress data and causes a combination user interface to display a trend of the fluid balance data within a fluid balance timeline. The integration engine determines when the trend of the fluid balance data exceeds a fluid balance limit and causes a fluid balance alarm or alert to be provided.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
A peritoneal dialysis (“PD”) system (10) including a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a filter body (110, 150, 190) housing first and second filter membranes (112a, 112b, such as a sterilizing grade or bacteria reduction filter membranes), the filter body (110, 150, 190) configured to be placed in different arrangements such that fresh PD fluid (i) flows through the first filter membrane (112a) and then through the second filter membrane (112b) or (ii) splits and flows through first and second filter membranes (112a, 112b) in parallel.
A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a filter membrane (120, such as a sterilizing grade or a bacteria reduction filter membrane) positioned and arranged such that fresh PD fluid flows through the filter membrane (120) into a filtered fluid compartment (106f), wherein the filtered fluid compartment (106f) includes an outlet (106t) to a port (106p), and wherein the port (106p) is in fluid communication with a used PD fluid tube (106u) positioned and arranged to carry used PD fluid past the filter membrane (120) without contacting the filter membrane (120). A method for priming filter set (100) is also disclosed.
A peritoneal dialysis system includes a control unit configured to (i) store a sleep state pattern for the patient, (ii) begin a patient drain followed by a patient fill when at least one sensor indicates that the patient is in a deep sleep state, (iii) extend a dwell period if the sleep state pattern indicates that the patient will enter a subsequent deep sleep state within a first time duration after a programmed dwell period, and (iv) shorten the dwell period if the sleep state pattern indicates that the patient will leave the deep sleep state within a second time duration after an end of the programmed dwell period. The system alternatively or additionally assesses or records a stress level of and/or a fluid/caloric intake by the patient and takes actions accordingly.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/16 - Devices for psychotechnicsTesting reaction times
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
62.
PERITONEAL DIALYSIS SYSTEM HAVING A PATIENT LINE FILTER
A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a filter membrane (120, e.g., a sterilizing grade filter membrane or a bacteria reduction filter membrane) positioned and arranged such that fresh PD fluid flows through the filter membrane (120) into a filtered fluid compartment (106f), wherein the filtered fluid compartment (106f) includes an outlet (1060) to a port (106p), and wherein the port (106p) is in fluid communication with a circumferential used PD fluid channel (106c) positioned and arranged to carry used PD fluid around the filter membrane (120) without contacting the filter membrane (120). A method for priming filter set (100) is also disclosed.
The present disclosure relates to improved lipid emulsions for providing parenteral nutrition, including ready-to-use parenteral nutrition formulations comprising such lipid emulsions. More particularly, the present disclosure is directed to improved lipid formulations or emulsions including multi-chamber containers comprising same, wherein the lipid emulsion contains DHA, EPA, and ARA in an optimized concentration and ratio, optionally in combination with choline and defined levels of phytosterols. The present disclosure further relates to methods of avoiding and/or treating liver damage and/or inflammation, and to methods for improving fatty acid profiles in plasma and certain tissues or organs especially of pediatric patients.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
A23L 33/11 - Plant sterols or derivatives thereof, e.g. phytosterols
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
A23D 7/00 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
A23D 7/01 - Other fatty acid esters, e.g. phosphatides
64.
PERITONEAL DIALYSIS SYSTEM HAVING A CAPILLARY PATIENT LINE FILTER
A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) (which may be a dual lumen patient line) extending from the PD machine (20); a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a plurality of hollow fiber membranes (120, e.g., sterilizing grade or bacteria reduction hollow fiber membranes) positioned and arranged such that fresh PD fluid flows through porous walls of the hollow fiber membranes (120) prior to exiting the filter set (100).
A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) including a filter housing (102) having a tubular filter membrane (120, such as a sterilizing grade or bacteria reduction filter membrane) positioned and arranged to filter fresh PD fluid flowing radially across the tubular filter membrane (120), and a transfer set-side port (106p) positioned and arranged to receive (i) filtered fresh PD fluid during a patient fill and (ii) used PD fluid during a patient drain.
A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) including a filter housing (102) having an upper housing plate (102u) and a lower housing plate (102l), and a filter membrane (112, such as a sterilizing grade or a bacteria reduction filter membrane) located between the upper housing plate (102u) and the lower housing plate (102l), the filter set (100) further including a lumen-side connector (104) configured to connect to the patient line (50), the lumen-side connector (104) connected to the filter housing (102) via at least one of a fresh PD fluid tube (106a) or a used PD fluid tube (106b). A method for manufacturing the filter set (100) is also disclosed.
The present disclosure relates to improved lipid emulsions for providing parenteral nutrition, including ready-to-use parenteral nutrition formulations comprising such lipid emulsions. More particularly, the present disclosure is directed to improved lipid formulations or emulsions including multi-chamber containers comprising same, wherein the lipid emulsion contains DHA, EPA, and ARA in an optimized concentration and ratio, optionally in combination with choline and defined levels of phytosterols. The present disclosure further relates to methods of avoiding and/or treating liver damage and/or inflammation, and to methods for improving fatty acid profiles in plasma and certain tissues or organs especially of pediatric patients.
A61J 7/00 - Devices for administering medicines orally, e.g. spoonsPill counting devicesArrangements for time indication or reminder for taking medicine
A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
The present disclosure relates to improved lipid emulsions for providing parenteral nutrition, including ready-to-use parenteral nutrition formulations comprising such lipid emulsions. More particularly, the present disclosure is directed to improved lipid formulations or emulsions including multi-chamber containers comprising same, wherein the lipid emulsion contains DHA, EPA, and ARA in an optimized concentration and ratio, optionally in combination with choline and defined levels of phytosterols. The present disclosure further relates to methods of avoiding and/or treating liver damage and/or inflammation, and to methods for improving fatty acid profiles in plasma and certain tissues or organs especially of pediatric patients.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61K 31/683 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A peritoneal dialysis (“PD”) machine includes a fresh/regenerated PD fluid pump, a used PD fluid pump, a sorbent cartridge located fluidically between the fresh/regenerated PD fluid pump and the used P fluid pump, a degassing tank located fluidically downstream from the sorbent cartridge, at least one valve located fluidically upstream of the degassing tank, and a control unit configured to control the fresh/regenerated PD fluid pump and the used PD fluid pump, the control unit further figured to operate the at least one valve to select whether fresh PD fluid or regenerated PD fluid is pumped by the fresh/regenerated PD fluid pump to the degassing tank.
A peritoneal dialysis (“PD”) system includes a PD fluid pump, a PD fluid heater positioned and arranged to heat fresh PD fluid pumped by the PD fluid pump, and a phase change material (“PCM”) device positioned and arranged to receive fresh PD fluid heated by the PD fluid heater. The PCM device includes a PCM having a melting temperature selected so that the PCM solidifies when underheated fresh PD fluid contacts the PCM transferring heat to the underheated fresh PD fluid. Alternatively or additionally, the PD system may include a different PCM device having a PCM with a melting temperature selected so that the PCM melts when overheated fresh PD fluid contacts the PCM thereby removing heat from the overheated fresh PD fluid. A configuration for the PCM device is also disclosed.
A system and method for self-aligning and connecting a device to a modular rack. The system includes a device comprising a connector receptacle configured to receive a connector plug and a bracket fixed to the device, a modular rack comprising the connector plug and a shelf configured to receive the bracket and guide the shelf in a plurality of directions. When the bracket of the device is inserted into the shelf of the modular rack, the shelf travels in the plurality of directions to self-align the connector plug of the modular rack to the connector receptacle of the device to ensure engagement of the connector plug to the connector receptacle.
H01R 13/631 - Additional means for facilitating engagement or disengagement of coupling parts, e.g. aligning or guiding means, levers, gas pressure for engagement only
H01R 13/52 - Dustproof, splashproof, drip-proof, waterproof, or flameproof cases
H01R 13/73 - Means for mounting coupling parts to apparatus or structures, e.g. to a wall
H01R 43/26 - Apparatus or processes specially adapted for manufacturing, assembling, maintaining, or repairing of line connectors or current collectors or for joining electric conductors for engaging or disengaging the two parts of a coupling device
72.
DAPTOMYCIN FORMULATIONS CONTAINING A COMBINATION OF SORBITOL AND MANNITOL
In an aspect, a method of manufacture of a pharmaceutically acceptable solid composition containing daptomycin includes drying an aqueous solution containing (i) water, (ii) the daptomycin, (iii) sorbitol in an amount of about 1.2 wt. % to about 9.0 wt. % of total volume of the aqueous composition and (iv) mannitol in an amount of about 0.6 wt. % to about 9.5 wt. % of total volume of the aqueous composition to form the solid composition. The drying can include a sublimation drying of about −25° C. to about 50° C. for a time period of about 15 hours to about 120 hours, most preferably about 15° C. for about 20 hours, optionally preceded and/or followed by one or more additional drying steps. Other aspects are the solid composition containing the daptomycin and also methods of treating a bacterial infection including administering a pharmaceutically acceptable product made by reconstituting the solid composition.
A system comprises a fluid generation arrangement (FGA), a user interface (UI), and a control unit. The FGA is operable to mix one or more concentrates with water to generate a treatment fluid for use in renal replacement therapy. The control unit is connected to the UI and arranged to configure the FGA by a computer-implemented method. In the method, the control unit receives, from the UI, a candidate set value of a selected component of the treatment fluid, calculates, for the candidate set value, a calculated composition of the treatment fluid, and displays, on the UI, a respective concentration value of one or more components other than the selected component in the calculated composition. By the system, a caretaker is made aware of consequential changes in the composition of the treatment fluid, in addition the selected component.
A dialysis fluid production system includes a water purification unit, at least one concentrate, a dialysis machine, a product container, and a recirculation container. The dialysis machine is configured to receive purified water from the water purification unit and to mix the purified water with the at least one concentrate to form dialysis fluid. The product container is positioned and arranged to receive the dialysis fluid from the dialysis machine, and the recirculation container is configured to receive an end of the drain line and an end of the dialysis fluid return line. Further, the recirculation container enables dialysis fluid to be recirculated from the drain line, through the dialysis fluid return line, back to the dialysis machine and is configured to be positioned adjacent to a facility drain such that overflow dialysis fluid flows from the recirculation container into the facility drain.
A drainage plate, a tray and a system for moist heat sterilization are provided. The drainage plate has a plurality of apertures sized to allow the fluid to pass through and includes a first region having a first aperture ratio; a second region having a second aperture ratio; and a third region having a third aperture ratio. The first region, the second region and the third region are sequentially arranged in a widthwise direction of the drainage plate, and the second aperture ratio is greater than the first aperture ratio and the third aperture ratio.
A peritoneal dialysis (“PD”) system includes a cycler having a weigh scale, a chamber for weighing by the weigh scale, a heater, a plurality of valves, a pump, and a control unit operable with the weigh scale, the heater, the plurality of valves and the pump; and a disposable set including a PD fluid container fitting within the chamber for weighing and heating, a supply line in fluid communication with the PD fluid container, a drain container fitting within the chamber for weighing, a drain line in fluid communication with the drain container, and a patient line positioned on an opposing side of the pump from the supply line and the drain lines, wherein the control unit is configured to operate the plurality of valves and the pump to pump used dialysis fluid to the drain container and fresh dialysis fluid from the PD fluid container.
The present disclosure relates to parenteral nutritional formulations, including ready-to-use parenteral nutrition formulations. More particularly, the present disclosure is directed to lipid formulations or emulsions and multi-chamber containers comprising same, wherein the lipid emulsion contains glycerophosphorylcholine as a choline source. The present disclosure further relates to methods of providing choline to a patient in need of parenteral nutrition and methods of avoiding and/or treating choline deficiency and liver damage.
A61K 9/00 - Medicinal preparations characterised by special physical form
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
A23D 7/01 - Other fatty acid esters, e.g. phosphatides
A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 31/661 - Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 36/05 - Chlorophycota or chlorophyta (green algae), e.g. Chlorella
A system and method are disclosed for detecting remaining battery voltage or capacity in an infusion device and generating alarms based on the detection. A battery lifetime extension method includes providing an infusion device that derives its power from a rechargeable battery. The infusion device may derive its power from a rechargeable battery. Furthermore, the infusion device receives, at predetermined intervals of time in real-time sensor data comprising a voltage, a change in the voltage over the predetermined interval of time, an average current, a temperature, and a remaining voltage or capacity reported by a battery gas gauge integrated circuit (“IC”) associated with the rechargeable battery. A customized neural network model utilizes the sensor data to determine an indicia of the actual remaining voltage or capacity of the rechargeable battery in real-time. The indicia may be used to lengthen and/or abate ongoing medical infusion therapy.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G01R 31/36 - Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
G01R 31/3842 - Arrangements for monitoring battery or accumulator variables, e.g. SoC combining voltage and current measurements
H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
A peritoneal dialysis (“PD”) system includes a housing and a dialysis fluid pump housed by the housing. The dialysis fluid pump includes a reusable pump body that accepts PD fluid for pumping and a flush flow port. The PD system also includes a dialysis fluid heater for heating PD fluid, a container configured to accept and hold PD fluid, a condenser in fluid communication with the container, a chamber in fluid communication with the condenser and a flush flow line extending from the chamber to the flush flow port. The PD system further includes a control unit programmed to cause the dialysis fluid heater to heat PD fluid in the container to form steam or water vapor. The steam or water vapor is condensed in the condenser into distilled water collected in the chamber and provided from the chamber to the flush flow port via the flush flow line.
A medical fluid container preparation system includes: a conveyor for conveying the medical fluid container; a water injector located along the conveyor; a mechanism for carrying the water injector towards and away from the medical fluid container; a sensor positioned and arranged to determine a location of the medical fluid container moving along the conveyor; and a control unit configured to read an output from the sensor and to cause (i) the mechanism to move the water injector towards the medical fluid container an amount based upon the location of the medical fluid container obtained from the sensor output and (ii) the water injector to inject a volume of water between the medical fluid container and an overpouch into which the medical fluid container is placed.
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
B65B 51/10 - Applying or generating heat or pressure or combinations thereof
B65B 57/14 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
B65B 57/16 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to stop, or to control the speed of, the machine as a whole
A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
84.
SYSTEMS AND METHODS FOR DIALYSIS FLUID PREPARATION IN BATCH DISPOSABLE
A peritoneal dialysis system includes a water purifier; a disposable set including a water line in fluid communication with the water purifier, a drain line for draining from the disposable set, and a disposable container including at least one chamber, the disposable container including at least one concentrate in one of the at least one chamber, and the disposable container positioned and arranged to hold a dialysis fluid prepared by mixing water from the water purifier and the at least one concentrate; and a control unit in communication with at least one sensor, for detecting a first property of water from the water purifier and a second property of the dialysis fluid.
The invention provides a system for characterizing an effluent sample from a patient undergoing peritoneal dialysis. The system features a container for enclosing the effluent sample, and optical system, an electrical system, and a processor. The optical system features a light source and a photodetector, the light source emitting a beam of radiation that passes through the container and irradiates the effluent sample, and the photodetector detecting the radiation after it irradiates the effluent sample to generate an optical signal. The electrical system typically features a first pair of electrodes and a second pair electrodes, both attached directly to the container and arranged to measure a capacitance of the effluent sample to generate a capacitance signal. The processor operates an algorithm that collectively processes the optical and capacitance signals to characterize the effluent sample.
A system is provided for characterizing an effluent sample from a patient undergoing peritoneal dialysis. The system features a container (30) for enclosing the effluent sample, an optical system, an electrical system, and a processor (13). The optical system features a light source (18, 24) and a photodetector (14, 54), the light source emitting a beam of radiation that passes through the container and irradiates the effluent sample, and the photodetector detecting the radiation after it irradiates the effluent sample to generate an optical signal. The electrical system features at least one pair of electrodes (38a, 38b) attached to the container and arranged to measure an electrical property of the effluent sample to generate a property signal. The processor operates an algorithm that collectively processes the optical and property signals to characterize the effluent sample.
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable medical software for receiving, storing,
displaying and transmitting data to and from medical
apparatus providing intravenous therapy to patients and to
and from medical apparatus monitoring the physiological
processes of patients undergoing intravenous therapy.
The present disclosure provides a method for flow rate compensation in devices, such as infusion pumps. In various embodiments, a computer-implemented method includes determining a location of a plurality of infusion pumps in a pump stack including the plurality of infusion pumps and a fluid supply connected to each of the plurality of infusion pumps. The computer-implemented method also includes determining a reference infusion pump, in the plurality of infusion pumps, and adjusting the flow rate for each infusion pump in the plurality of infusion pumps based on the distance between the infusion pump and the reference infusion pump.
The present invention provides a hemostatic composite sponge comprising oxidized cellulose and an essentially gelatin-free bioadhesive material stably associated with said sponge and present in an organized pattern on said sponge.
A61F 13/0203 - Adhesive bandages or dressings with fluid retention members
A61F 13/0246 - Adhesive bandages or dressings characterised by the skin-adhering layer
A61F 13/15 - Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the bodySupporting or fastening means thereforTampon applicators
A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
A hemodialysis system is disclosed. The hemodialysis system includes a dialyzer and an online dialysate generation system comprising a water inlet line and a drain line. The hemodialysis system also includes a disposable set comprising a supply tube fluidly connected to online dialysate generation system and a dialysate pumping tube fluidly connected to the dialyzer. The hemodialysis system further includes a dialysis instrument comprising a dialysate pump head and a motor positioned and arranged to operate the dialysate pump head. The dialysis instrument operates the dialysate pump head to move fresh dialysate from the online dialysate generation system through the dialysate pumping tube to the dialyzer.
A syringe pump including a housing with a syringe accepting region, an accelerometer configured to detect a tube pull, a syringe holding system configured to hold a syringe in the syringe accepting region, a drive mechanism, and a drive head operatively coupled to the drive mechanism. The drive head is configured to engage a piston of a syringe held by the syringe holding system.
A peritoneal dialysis (“PD”) machine includes a water pump; a concentrate pump; a water valve, and an inlet to the water valve positioned to receive purified water; a concentrate valve, and an inlet to the concentrate valve positioned to receive PD fluid concentrate; a mixing line located downstream from the water pump and the a concentrate pump; a conductivity sensor positioned to sense mixed purified water and PD fluid concentrate that form fresh PD fluid; a flexible patient line configured to bring fresh PD fluid to and remove used PD fluid from a patient; and a control unit configured to control the water pump, the concentrate pump, the water valve and the concentrate valve, to receive an output from the conductivity sensor, and to run a disinfection sequence in which (i) the inlet to the concentrate valve alternatively receives disinfectant or (ii) the flexible patient line alternatively receives disinfectant.
A system includes a server including a clock and a plurality of medical devices in network communication with the server. Each medical device includes at least one alarm mechanism and an internal clock. A first medical device of the plurality of medical devices is configured to receive a clock synchronization data from the server, update the internal clock of the first medical device based on the clock synchronization data, provide an alarm signal of a first type at a first time, and provide a subsequent alarm signal of the first type at a second time. The second time occurs at a predetermined interval from the first time. Additionally, the second time is the same time the alarm signal of the first type is provided by a second medical device of the plurality of medical device.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
96.
DEVICE FOR ADMINISTRATION OF A THERAPEUTIC AGENT SOLUTION AND METHOD COMPRISING SAME
A device and method for parenteral administration of a solution of a therapeutic agent include a fluid reservoir having a chamber for holding fluid and an outlet port. The outlet port is fluidly coupled to a therapeutic agent conduit having a fluid inlet and a fluid outlet that define a fluid flow path. An infusion device is fluidly connected to the fluid outlet of the therapeutic agent conduit. The infusion device is capable of parenteral administration of fluid. A polymeric matrix is disposed in the therapeutic agent conduit, the polymeric matrix having a therapeutic agent dispersed therein. The therapeutic agent is at least partially dissolvable when contacted by fluid and a solution of the therapeutic agent is formed when contacted by the fluid.
A digital communication apparatus for transmission of data from a medical device is disclosed. In an example, the digital communication apparatus includes an input interface configured for communicative coupling to a medical device and an output interface configured for communicative coupling to a medical network and a remote server. A processor of the digital communication apparatus receives medical data in a first data format from the medical device via the input interface. The processor selects a first subset of the medical data for transmission in the first data format to the remote server via an Ethernet port or a wireless port of the output interface. The processor also converts a second subset of the medical data to the second data format and transmits the second subset of the medical data in the second data format to the medical network via a serial port or the Ethernet port.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G06F 13/42 - Bus transfer protocol, e.g. handshakeSynchronisation
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
A graph database for outbreak tracking and management is disclosed. In an example embodiment, an outbreak management system includes a memory device storing instructions that define a graph database for disease outbreak tracking. The instructions specify for a given host that a host node is created and an episode node is connected to the host node via a ‘case’ link. The episode node is associated with episode parameters that are related to a disease classification of the host. In addition, the instructions specify that an outbreak node is connected to the episode node via a ‘part of’ link to indicate that the host has become part of an outbreak of the disease. The outbreak node is connected to a definition node via a ‘defined as’ link. The definition node specifies disease parameters of the disease for outbreak tracking.
G06F 3/0484 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
G06T 11/20 - Drawing from basic elements, e.g. lines or circles
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/80 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for detecting, monitoring or modelling epidemics or pandemics, e.g. flu
G16H 70/60 - ICT specially adapted for the handling or processing of medical references relating to pathologies
A peritoneal dialysis system includes: a dialysis fluid pump including a pump actuator and a dialysis fluid contacting portion actuated by the pump actuator; a fresh dialysis fluid valve located upstream of the pump and including a fresh valve actuator and a dialysis fluid contacting portion actuated by the fresh valve actuator; a patient line valve located downstream of the pump and including a patient line valve actuator and a dialysis fluid contacting portion actuated by the patient line valve actuator; a drain valve positioned and arranged to receive used dialysis fluid from the patient and including a drain valve actuator and a dialysis fluid contacting portion; a patient line extending from the drain valve; and a fluid loop including dialysis fluid contacting portions of the pump, the fresh dialysis fluid valve, the patient line valve and the drain valve, and wherein the patient line extends from the fluid loop.
A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
B65D 75/28 - Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
B65D 81/26 - Adaptations for preventing deterioration or decay of contentsApplications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, fluids, e.g. exuded by contentsApplications of corrosion inhibitors or desiccators
