The present disclosure relates to methods for increasing recovery and purity of a secreted protein of interest, recovered proteins from the methods, and uses of the proteins.
Provided herein are compositions with enhanced protein content, protein compositions with improved functionality, and methods for the preparation thereof.
A23L 15/00 - Egg productsPreparation or treatment thereof
A23J 1/14 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seedsObtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from press-cake or oil-bearing seeds
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
29 - Meat, dairy products, prepared or preserved foods
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Eggs; egg whites; egg yolks; egg substitutes; egg products; proteins; protein substitutes; and protein products Protein, namely, egg-white protein made through fermentation for use in manufacture; proteins for the food industry; proteins for use in the manufacture of food products and food supplements; enzymes for the food industry; enzyme preparations for the food industry; bioactives for the food industry being chemicals for use in the manufacture of foods Bioactives for the food industry, namely, fermentation byproducts, dietary, vitamin or nutritional supplements, and branch chain amino acids, for nutritional and medical purposes
29 - Meat, dairy products, prepared or preserved foods
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Eggs; egg whites; egg yolks; egg substitutes; egg products; proteins; protein substitutes; and protein products Protein, namely, egg-white protein made through fermentation for use in manufacture; proteins for the food industry; proteins for use in the manufacture of food products and food supplements; enzymes for the food industry; enzyme preparations for the food industry; bioactives for the food industry being chemicals for use in the manufacture of foods Bioactives for the food industry, namely, fermentation byproducts, dietary, vitamin or nutritional supplements, and branch chain amino acids, for nutritional and medical purposes
A fermentation monitoring platform obtains data regarding a biological sample collected during a fermentation process. The data comprises Fourier transform infrared (FTIR) data describing the content of the biological sample. The fermentation monitoring platform determines one or more proteins of interest (POI) present in the biological sample by applying a first vector representation of the FTIR data to a first machine-learning model. For each POI present in the biological sample, the fermentation monitoring platform determines a titer of the POI by applying a second vector representation of the FTIR data to a second machine-learning model. The fermentation monitoring platform identifies one or more process excursions during the fermentation process based on the POIs present in the biological sample and the titer of each present POI and modifies instructions regarding the fermentation process based on the one or more identified process excursions.
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids
G16B 50/30 - Data warehousingComputing architectures
G05B 19/042 - Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
C12M 1/36 - Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
G05B 13/04 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric involving the use of models or simulators
8.
BEVERAGE CLARIFICATION USING RECOMBINANT OVA OR OVD
C12G 3/08 - Preparation of other alcoholic beverages by methods for altering the composition of fermented solutions or alcoholic beverages not provided for in groups
10.
Protein compositions and consumable products thereof
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
The present disclosure provides methods for producing consumable recombinant proteins that are substantially free from herein-disclosed undesired byproducts for a consumable food product. The method comprises, in part, obtaining a composition from a process used to produce recombinant egg protein, processing under condition to separate the recombinant protein from the cell byproducts; concentrating the separated recombinant protein and collecting the recombinant protein concentrate comprising recombinant egg protein.
The present disclosure provides methods for producing consumable recombinant proteins that are substantially free from herein-disclosed undesired byproducts.
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
Provided are systems and methods for production of recombinant proteins in engineered microorganisms while reducing impurities produced in the culture.
A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
C07K 14/395 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from fungi from yeasts from Saccharomyces
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
15.
PROTEIN COMPOSITIONS AND CONSUMABLE PRODUCTS THEREOF
Provided herein are compositions with enhanced protein content, protein compositions with improved functionality, and methods for the preparation thereof.
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 3/20 - Proteins from microorganisms or unicellular algae
A23J 3/22 - Working-up of proteins for foodstuffs by texturising
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
16.
PROTEIN COMPOSITIONS AND CONSUMABLE PRODUCTS THEREOF
Provided herein are compositions with enhanced protein content, protein compositions with improved functionality, and methods for the preparation thereof.
Provided are systems and methods for production of recombinant proteins in engineered microorganisms. The systems and methods provide high-titer expression of recombinant proteins in large scale production and are particularly useful for expressing heterologous proteins in a microbial host, such as food-based proteins or other protein types such as therapeutic proteins and enzymes. Disclosed are also kits for making the same.
Provided are systems and methods for production of recombinant proteins in engineered microorganisms. The systems and methods provide high-titer expression of recombinant proteins in large scale production and are particularly useful for expressing heterologous proteins in a microbial host, such as food-based proteins or other protein types such as therapeutic proteins and enzymes. Disclosed are also kits for making the same.
29 - Meat, dairy products, prepared or preserved foods
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Egg substitute; egg product; egg substitute in powder and liquid form; egg product for use as a protein substitute; egg product for use as protein fortification; protein for use as a meat substitute Protein for use in manufacture; egg-white protein for use in manufacture; proteins for the food industry; proteins for use in the manufacture of food products and food supplements; proteins for use in the manufacture of a wide variety of goods
The present disclosure provides methods and systems for recipe optimization for food applications. A recipe optimization system generates a seed dataset comprising an initial randomized set of seed recipes based on a list of starting ingredients. The recipe optimization system obtains feedback data for a plurality of food products made using the initial randomized set of seed recipes during an initial experimental run. The recipe optimization system generates a plurality of candidate recipes based at least on (1) the feedback data and (2) one or more recipe constraints. The recipe optimization systems applies a predictive model to rank the plurality of candidate recipes according and selects one or more top-ranked candidate recipes for one or more subsequent experimental runs to further optimize the objective function.
Provided herein are methods for precision fermentation that iteratively build models, collect data broadly, and deliver information to users both directly (via API or user interface) or through third party software. Furthermore, in addition to traditional facades and coordinated operations like sagas, subsystems often require the ad-hoc ability to communicate with each other like to operate on data about the same sample or strain across multiple services.
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids
G16B 50/30 - Data warehousingComputing architectures
22.
SYSTEMS AND METHODS FOR ALGORITHMICALLY ESTIMATING PROTEIN CONCENTRATIONS
Disclosed is a computer-implemented method and system for estimating protein concentrations. The method comprises first generating a synthetic dataset based at least on protein signature or fingerprint data. Then, the method comprises training a model using in part the synthetic dataset, without requiring protein-specific calibration or training. Finally, the method comprises using the model to estimate or predict a percentage amount of a specific protein of interest (POI) in one or more heterogeneous samples, even if the POI was not used in modeling at the time of training.
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.
A23J 1/08 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs
A23J 1/09 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs separating yolks from whites
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
C07K 14/79 - Transferrins, e.g. lactoferrins, ovotransferrins
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
25.
PURIFIED PROTEIN COMPOSITIONS AND METHODS OF PRODUCTION
The present disclosure provides methods for producing consumable recombinant proteins that are substantially free from herein-disclosed undesired byproducts.
C07K 1/36 - ExtractionSeparationPurification by a combination of two or more processes of different types
B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
The present disclosure provides engineered eukaryotic cells comprising a surface displayed fusion proteins comprising a catalytic domain of an enzyme and an anchoring domain of a glycosylphosphatidylinositol (GPI)-anchored protein and methods of use.
Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.
A23J 1/08 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs
A23J 1/09 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs separating yolks from whites
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
C07K 14/79 - Transferrins, e.g. lactoferrins, ovotransferrins
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
C07K 14/395 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from fungi from yeasts from Saccharomyces
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
C12N 1/22 - Processes using, or culture media containing, cellulose or hydrolysates thereof
C12N 15/52 - Genes encoding for enzymes or proenzymes
The present disclosure provides engineered eukaryotic cells comprising a surface displayed fusion proteins comprising a catalytic domain of an enzyme and an anchoring domain of a glycosylphosphatidylinositol (GPI)-anchored protein and methods of use.
C40B 40/02 - Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cellsLibraries contained in or displayed by vectors, e.g. plasmidsLibraries containing only microorganisms or vectors
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
Disclosed is a method for identifying a subset of high-expressing proteins. The method comprises (a) generating a distance matrix relating a plurality of amino acid sequences of a training set of amino acid sequences from a plurality of training proteins. The method also comprises (b) performing dimensionality reduction on a set of the plurality of amino acid sequence distances of the distance matrix to produce a set of features. The method also comprises (c) generating one or more trained models by training a set of classifiers or regressors on the set of features. The method also comprises (d) using the one or more trained models, analyzing a test set of amino acid sequences from the plurality of proteins, to identify whether the subset of proteins within the plurality of proteins comprises high-expressing proteins.
G16B 15/00 - ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
34.
PROTEIN COMPOSITIONS AND CONSUMABLE PRODUCTS THEREOF
Provided herein are compositions with enhanced protein content, protein combinations with high solubility and improved functionality, including foam stability and foam capacity, and methods for the preparation thereof.
The present disclosure relates to methods for increasing recovery and purity of a secreted protein of interest using salting-out with ammonium sulfate and pH adjustment to about or below the isoelectric point of the protein of interest. The present disclosure further relates to the recovered proteins from the methods, and their uses.
Provided herein are methods for preparing a protein composition having a reduced quantity of a recombinant cell byproduct which provides an undesirable color to a protein. The methods involve the use of absorbents or flocculants that capture, trap or isolate the recombinant cell byproduct. The methods also involve oxidation of the recombinant cell byproduct with an oxidizing agent (e.g. hydrogen peroxide) or light (e.g. photochemical oxidation).
Provided herein are compositions with enhanced protein content, protein compositions with improved functionality, and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
42.
METHODS AND COMPOSITIONS FOR EGG WHITE PROTEIN PRODUCTION
Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.
C07K 14/79 - Transferrins, e.g. lactoferrins, ovotransferrins
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
A23L 15/00 - Egg productsPreparation or treatment thereof
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 1/09 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs separating yolks from whites
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
43.
COMPOSITIONS FOR PREPARING ANIMAL-FREE EGG-LIKE PRODUCTS
A23L 15/00 - Egg productsPreparation or treatment thereof
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 1/14 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seedsObtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from press-cake or oil-bearing seeds
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
The present disclosure provides methods for producing consumable recombinant proteins that are substantially free from herein-disclosed undesired byproducts.
C07K 1/36 - ExtractionSeparationPurification by a combination of two or more processes of different types
B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
C07K 1/16 - ExtractionSeparationPurification by chromatography
The present disclosure provides methods for producing recombinant proteins that are substantially free from undesired byproduct comprising exopolysaccharides and off-flavor components. The methods of purification involve anionic resins, cationic exchange resins, flocculants, adsorbents and/or treatment with enzymes.
The present disclosure provides methods for producing recombinant proteins that are substantially free from undesired byproduct comprising exopolysaccharides and off-flavor components. The methods of purification involve anionic resins, cationic exchange resins, flocculants, adsorbents and/or treatment with enzymes.
Provided are systems and methods for production of recombinant proteins in engineered microorganisms while reducing impurities produced in the culture.
Provided are systems and methods for production of recombinant proteins in engineered microorganisms while reducing impurities produced in the culture.
Provided herein are compositions with enzymatically active enzymes produced recombinantly, enhanced protein content and methods for the preparation thereof.
C12N 9/36 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on beta-1, 4 bonds between N-acetylmuramic acid and 2-acetylamino 2-deoxy-D-glucose, e.g. lysozyme
Disclosed is a computer-implemented method and system for estimating protein concentrations. The method comprises first generating a synthetic dataset based at least on protein signature or fingerprint data. Then, the method comprises training a model using in part the synthetic dataset, without requiring protein-specific calibration or training. Finally, the method comprises using the model to estimate or predict a percentage amount of a specific protein of interest (POI) in one or more heterogeneous samples, even if the POI was not used in modeling at the time of training.
viavia API or user interface) or through third party software. Furthermore, in addition to traditional facades and coordinated operations like sagas, subsystems often require the ad-hoc ability to communicate with each other like to operate on data about the same sample or strain across multiple services.
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 3/20 - Proteins from microorganisms or unicellular algae
A23L 15/00 - Egg productsPreparation or treatment thereof
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 3/20 - Proteins from microorganisms or unicellular algae
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, protein combinations with high solubility and improved functionality, including foam stability and foam capacity, and methods for the preparation thereof. The compositions comprise recombinantly produced ovomucoid (rOVD) protein and/or recombinantly produced ovalbumin (rOVA) protein.
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
Provided herein are compositions with enhanced protein content, protein combinations with high solubility and improved functionality, including foam stability and foam capacity, and methods for the preparation thereof. The compositions comprise recombinantly produced ovomucoid (rOVD) protein and/or recombinantly produced ovalbumin (rOVA) protein.
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
Goods & Services
Casein for the food industry; Casein for industrial purposes; Collagen for the food industry in the nature of collagen for industrial purposes; Collagen for industrial purposes Collagen preparations for cosmetic purposes Collagen for medical purposes Milk; Dried milk for food; Dried milk powder; Whey; Dry whey
67.
NON-ANIMAL BASED PROTEIN SOURCES WITH FUNCTIONAL PROPERTIES
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Enzymes for use in the biochemical industry; Enzymes for scientific and research purposes; Enzymes for use in the genetic analysis industry in the nature of enzymes for scientific and research purposes; Enzymes for use in the ethanol industry; Enzymes for use in the dairy industry; Enzymes for use in the tanning of leather industry; Enzymes for use in the agricultural industry; Enzymes for use in the bakery industry; Enzymes for use in the detergent industry; Enzymes for use in forensic research in the nature of enzymes for scientific and research purposes; Enzymes for use in the wine industry; Enzymes for use in drug detection for industrial, scientific and research purposes; Enzymes for use in the manufacture of alcohol and biological based chemicals; Enzymes and proteins for use in the manufacture of feedstuffs for animals and in the manufacture of fodder; Enzymes for use in fermentation in the manufacturing of alcohol for food and biofuel applications; Enzymes and proteins for use in the pharmaceutical industry; Enzymes and proteins for use in the nutritional and dietary supplements industry; Enzymes and proteins for use in cosmetics; Enzymes and proteins for use in cellular agriculture and cell culture Enzymes for use in medical diagnostic purposes Product development consultation and product research and development services for others in the field of food and beverage ingredients; Engineering services related to the production of proteins using fermentation and biotechnology in the field of food and food ingredient development; Methods of production and purification of animal proteins using microbes instead of animals being product development in the field of food and food ingredients; Food research; Technical consultancy in relation to technical research in the field of food and food ingredient development; Product research and development for the food ingredient and food industry; Professional technical consultancy in relation to the development of fermentation technologies in the fields of food and beverage technology; Scientific consultancy and advisory services relating to the scientific analysis and development of animal proteins made without the animal for use in cosmetics, pharmaceutical, material processing, food safety, food and beverages
69.
MODIFICATION OF PROTEIN GLYCOSYLATION IN MICROORGANISMS
The present disclosure contemplates methods for modifying post-translational modification of proteins recombinantly expressed a microbial host to improve one or more properties of the recombinant protein.
01 - Chemical and biological materials for industrial, scientific and agricultural use
29 - Meat, dairy products, prepared or preserved foods
Goods & Services
Proteins for the food industry; Enzymes for the food industry; Enzyme preparations for the food industry; Bioactives for the food industry being chemicals for use in the manufacture of foods Eggs; egg whites; egg yolks; egg substitutes
Provided are systems and methods for high-yield production of recombinant proteins in engineered microorganisms. Also provided is an engineered host cell for expressing a heterologous protein, said engineering host cell may comprise at least three different expression cassettes integrated into the genome of the engineered host cell wherein; a first expression cassette may comprise a first promoter operably linked to a heterologous gene sequence encoding the heterologous protein; a second expression cassette may comprise a second promoter operably linked to a heterologous gene sequence encoding the heterologous protein; a third expression cassette may comprise a third promoter operably linked to a helper factor sequence.
Provided are systems and methods for high-yield production of recombinant proteins in engineered microorganisms. Also provided is an engineered host cell for expressing a heterologous protein, said engineering host cell may comprise at least three different expression cassettes integrated into the genome of the engineered host cell wherein; a first expression cassette may comprise a first promoter operably linked to a heterologous gene sequence encoding the heterologous protein; a second expression cassette may comprise a second promoter operably linked to a heterologous gene sequence encoding the heterologous protein; a third expression cassette may comprise a third promoter operably linked to a helper factor sequence.
Provided herein are compositions with enzymatically active enzymes produced recombinantly, enhanced protein content and methods for the preparation thereof.
A23L 29/269 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
C12P 19/06 - Xanthan, i.e. Xanthomonas-type heteropolysaccharides
Provided herein are compositions with enzymatically active enzymes produced recombinantly, enhanced protein content and methods for the preparation thereof.
C12N 9/36 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on beta-1, 4 bonds between N-acetylmuramic acid and 2-acetylamino 2-deoxy-D-glucose, e.g. lysozyme
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
C12P 19/06 - Xanthan, i.e. Xanthomonas-type heteropolysaccharides
A23L 29/269 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
(1) Proteins for use in the manufacture of food; enzymes for the food industry; enzyme preparations for the food industry; bioactives for the food industry, namely, yeast fermentation byproducts, namely, oligosaccharides in the nature of unprocessed polymers, fatty acids, carotenoids, lutein, zeaxanthin, and branch chain amino acids, all being chemicals for use in the manufacture of foods.
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, compositions with functional proteins, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
Provided herein are compositions with enhanced protein content, proteins with high solubility, protein combinations and methods for the preparation thereof.
Provided herein are recombinant animal-free food compositions comprising egg-white proteins such as ovalbumin, ovotransferrin and lysozyme and methods of making such food compositions.
C07K 14/79 - Transferrins, e.g. lactoferrins, ovotransferrins
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 1/09 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs separating yolks from whites
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
90.
MODIFICATION OF PROTEIN GLYCOSYLATION IN MICROORGANISMS
The present disclosure contemplates methods for modifying post-translational modification of proteins recombinantly expressed a microbial host to improve one or more properties of the recombinant protein.
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
91.
Methods and compositions for egg white protein production
Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.
C07K 14/79 - Transferrins, e.g. lactoferrins, ovotransferrins
C07K 14/465 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from birds
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
A23L 15/00 - Egg productsPreparation or treatment thereof
A23J 1/18 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from yeasts
A23J 1/09 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from eggs separating yolks from whites
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
Provided herein are compositions, proteins, polynucleotides, expression vectors, host cells, kits, and systems for producing egg white proteins, as well as methods of using the same.
