Bone void filler consisting of synthetic materials; Bone void fillers consisting of artificial materials; Bone void fillers consisting primarily of synthetic materials and also incorporating biological materials; Synthetic media for use in the augmentation of bone and tissue for medical purposes; Artificial biomaterials for augmentation of bone and tissue for medical purposes; Synthetic filler and extender material to serve as replacement for bone; Substitutes for bones; Bone substitutes for surgical use; Artificial bone growth media; Bone repair compound for use in orthopedic surgery; Biodegradable bone fixation implants; Bone implants composed of artificial materials; Artificial bone parts to be implanted in natural bones
Bone void filler consisting of synthetic materials; Bone void fillers consisting of artificial materials; Bone void fillers consisting primarily of synthetic materials and also incorporating biological materials; Synthetic media for use in the augmentation of bone and tissue for medical purposes; Artificial biomaterials for augmentation of bone and tissue for medical purposes; Synthetic filler and extender material to serve as replacement for bone; Substitutes for bones; Bone substitutes for surgical use; Artificial bone growth media; Bone repair compound for use in orthopedic surgery; Biodegradable bone fixation implants; Bone implants composed of artificial materials; Artificial bone parts to be implanted in natural bones
Bone void filler consisting of synthetic materials; Bone void fillers consisting of artificial materials; Bone void fillers consisting primarily of synthetic materials and also incorporating biological materials; Synthetic media for use in the augmentation of bone and tissue for medical purposes; Artificial biomaterials for augmentation of bone and tissue for medical purposes; Synthetic filler and extender material to serve as replacement for bone; Substitutes for bones; Bone substitutes for surgical use; Artificial bone growth media; Bone repair compound for use in orthopedic surgery; Biodegradable bone fixation implants; Bone implants composed of artificial materials; Artificial bone parts to be implanted in natural bones
4.
Self-Drilling Bone Cement Delivery Cannula and Methods for Use
The present disclosure relates to a device including an elongated hollow shaft having a proximal end and a distal end. The device also includes a first attachment mechanism coupled to the proximal end of the elongated hollow shaft. The device also includes a rod having a proximal end and a distal end. The rod is removably positioned at least partially within a lumen of the elongated hollow shaft. The device also includes a second attachment mechanism coupled to the rod between the proximal end of the rod and the distal end of the rod. The first attachment mechanism and the second attachment mechanism are configured to be removably coupled to one another. The device also includes a cap configured to be removably coupled to the second attachment mechanism.
The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
The present disclosure relates to an orthopedic implant. The orthopedic implant includes an elongated member having a first end and a second end opposite the first end. The elongated member is tapered at the second end such that a width of the second end is less than a width of the first end. The orthopedic implant also includes a first channel positioned on a first side of the elongated member and extending from the first end to the second end. The orthopedic implant also includes a second channel positioned on a second side of the elongated member and extending from the first end to the second end. The orthopedic implant also includes one or more through holes connecting the first channel to the second channel.
The present disclosure relates to an orthopedic implant. The orthopedic implant includes an elongated member having a first end and a second end opposite the first end. The orthopedic implant also includes a porous coating secured to an exterior surface of the elongated member. The porous coating includes magnesium phosphate.
The present disclosure relates to a bio-material composition comprising a dry potassium phosphate based mixture omprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and an antibiotic, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry otassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, and wherein the proteoglycans act as active regulators of collagen fibrillogenesis to thereby structure tissue of a patient by organizing a bone extracellular matrix.
The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
The present disclosure provides a bio-material composition and method of use in craniomaxillofacial surgery. An example method comprises: accessing a space defined between adjacent bone structures in a head of a patient; mixing magnesia, potassium biphosphate, and a calcium phosphate with an aqueous solution to form an activated bone fusion slurry (ABFS); applying an effective amount of the ABFS to the space between the adjacent bone structures; allowing the ABFS to set forming a bonded bone structure; and permitting bone growth into the bonded bone structure providing fusion of the two adjacent bone structures, wherein the ABFS promotes fusion of the two adjacent bone structures without the need for additional physical fixation devices.
The present disclosure relates to a device including an elongated hollow shaft having a proximal end and a distal end. The device also includes a first attachment mechanism coupled to the proximal end of the elongated hollow shaft. The device also includes a rod having a proximal end and a distal end. The rod is removably positioned at least partially within a lumen of the elongated hollow shaft. The device also includes a second attachment mechanism coupled to the rod between the proximal end of the rod and the distal end of the rod. The first attachment mechanism and the second attachment mechanism are configured to be removably coupled to one another. The device also includes a cap configured to be removably coupled to the second attachment mechanism.
The present disclosure provides bio-material composition, comprising a dry potassium phosphate based mixture comprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and a plurality of spherically-shaped polymers, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the spherically-shaped polymers are between about 1-5 weight percent of the dry composition, and wherein the spherically-shaped polymers are absorbed faster than the remaining components of the reabsorbable bio-material slurry to thereby form pockets within the bio-material composition that enhance reabsorption of the bio-material composition.
A61L 27/48 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
The present disclosure relates to a spinal implant for insertion between two adjacent vertebrae. The spinal implant includes a frame sized to be inserted between the two adjacent vertebrae. The spinal implant also includes a lattice structure disposed at least partially within the frame and exposed on at least one side of the frame to permit bone growth into the lattice structure. The lattice structure comprises a magnesium phosphate material.
The present disclosure relates to an orthopedic instrument. The orthopedic instrument includes an elongated hollow shaft having a proximal end and a distal end. The orthopedic instrument also includes a rod having a proximal end and a distal end. The rod is positioned at least partially within a lumen of the elongated hollow shaft. The orthopedic instrument also includes a cutting head having a proximal end and a distal end, wherein the proximal end of the cutting head is coupled to the distal end of the rod. The cutting head is rotatably coupled to the distal end of the elongated hollow shaft between the proximal end of the cutting head and the distal end of the cutting head. A movement of the rod within the lumen of the elongated hollow shaft in a distal direction causes cutting head to transition from a straight configuration to an angled configuration.
The present disclosure relates to a method for treating a bone defect using a bio-material with increased porosity and reabsorption characteristics, the method comprising: (a) mixing a dry potassium phosphate based mixture with an aqueous solution to form a reabsorbable bio-material slurry, wherein the dry potassium phosphate based mixture comprises MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, and calcium sodium phosphosilicate, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, (b) accessing a void of a bone defect within a bone, and (c) filling the void with the reabsorbable bio-material slurry, wherein the reabsorbable bio-material slurry is osteoconductive and osteoinductive, thereby enabling new bone growth in the void.
The present disclosure relates to an orthopedic implant. The orthopedic implant includes an elongated member having a first end and a second end opposite the first end. The orthopedic implant also includes a porous coating secured to an exterior surface of the elongated member. The porous coating includes magnesium phosphate.
The present disclosure relates to an orthopedic implant. The orthopedic implant includes an elongated member having a first end and a second end opposite the first end. The elongated member is tapered at the second end such that a width of the second end is less than a width of the first end. The orthopedic implant also includes a first channel positioned on a first side of the elongated member and extending from the first end to the second end. The orthopedic implant also includes a second channel positioned on a second side of the elongated member and extending from the first end to the second end. The orthopedic implant also includes one or more through holes connecting the first channel to the second channel.
A61B 17/58 - Surgical instruments or methods for treatment of bones or jointsDevices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
The present disclosure provides a bio-material composition and method of use in craniomaxillofacial surgery. An example method comprises: accessing a space defined between adjacent bone structures in a head of a patient; mixing magnesia, potassium biphosphate, and a calcium phosphate with an aqueous solution to form an activated bone fusion slurry (ABFS); applying an effective amount of the ABFS to the space between the adjacent bone structures; allowing the ABFS to set forming a bonded bone structure; and permitting bone growth into the bonded bone structure providing fusion of the two adjacent bone structures, wherein the ABFS promotes fusion of the two adjacent bone structures without the need for additional physical fixation devices.
A61L 27/12 - Phosphorus-containing materials, e.g. apatite
A61L 27/42 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having an inorganic matrix
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
The present disclosure relates to a bio-material composition comprising a dry potassium phosphate based mixture comprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and an antibiotic, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, and wherein the proteoglycans act as active regulators of collagen fibrillogenesis to thereby structure tissue of a patient by organizing a bone extracellular matrix.
A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
A61L 27/42 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having an inorganic matrix
Bio-adhesive bone substitute for medical and dental use, namely, magnesium-based bone void fillers consisting of synthetic materials for medical purposes
Bio-adhesive bone substitute for medical and dental use, namely, magnesium-based bone void fillers consisting of synthetic materials for medical purposes
Bio-adhesive bone substitute for medical and dental use, namely, magnesium-based bone void fillers consisting of synthetic materials for medical purposes
Bio-adhesive bone substitute for medical and dental use, namely, magnesium-based bone void fillers consisting of synthetic materials for medical purposes
Bio-adhesive bone substitute for medical and dental use, namely, magnesium-based bone void fillers consisting of synthetic materials for medical purposes
Bio-adhesive bone substitute for medical and dental use, namely, magnesium-based bone void fillers consisting of synthetic materials for medical purposes
The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
The present invention relates to a bio-material composition and methods of use. Among the preferred embodiments are methods for fusing objects to bone and methods for fixing bone voids without the need for BMP-2. One or more preferred embodiments relate to methods for fusing objects (including bone, tendons, ligaments and implants) to bone using the invented bio-material composition.
The present invention relates to a material and method for providing spinal fusion. One preferred method comprises: accessing the intervertebral space defined between adjacent vertebrae; mixing magnesia, potassium biphosphate, and a calcium phosphate with an aqueous solution forming an activated spinal fusion slurry (ASFS); applying an effective amount of the ASFS to the intervertebral space between adjacent vertebrae; allowing the ASFS to set forming a bonded vertebrae structure; permitting bone growth into the bonded vertebrae structure providing fusion of the two adjacent vertebrae.
The present disclosure relates to a bio-material composition comprising a dry potassium phosphate based mixture comprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and an antibiotic, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, and wherein the proteoglycans act as active regulators of collagen fibrillogenesis to thereby structure tissue of a patient by organizing a bone extracellular matrix.
A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
A61L 27/42 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having an inorganic matrix
The present disclosure provides a bio-material composition and method of use in craniomaxillofacial surgery. An example method comprises: accessing a space defined between adjacent bone structures in a head of a patient; mixing magnesia, potassium biphosphate, and a calcium phosphate with an aqueous solution to form an activated bone fusion slurry (ABFS); applying an effective amount of the ABFS to the space between the adjacent bone structures; allowing the ABFS to set forming a bonded bone structure; and permitting bone growth into the bonded bone structure providing fusion of the two adjacent bone structures, wherein the ABFS promotes fusion of the two adjacent bone structures without the need for additional physical fixation devices.
A61L 27/12 - Phosphorus-containing materials, e.g. apatite
A61L 27/42 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having an inorganic matrix
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
