Quadram Institute Bioscience

United Kingdom

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2025 July 1
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IPC Class
A61K 39/02 - Bacterial antigens 9
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria 9
C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora 7
A61K 39/00 - Medicinal preparations containing antigens or antibodies 6
A61K 39/112 - SalmonellaShigella 5
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NICE Class
05 - Pharmaceutical, veterinary and sanitary products 3
29 - Meat, dairy products, prepared or preserved foods 3
30 - Basic staples, tea, coffee, baked goods and confectionery 3
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09 - Scientific and electric apparatus and instruments 2
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Status
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Registered / In Force 32

1.

METHODS AND MATERIALS FOR PROSTHETIC JOINT INFECTION DETECTION AND DIAGNOSIS

      
Application Number GB2025050048
Publication Number 2025/149760
Status In Force
Filing Date 2025-01-13
Publication Date 2025-07-17
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Webber, Mark
  • Sims, Leanne
  • Mcnamara, Iain

Abstract

A biomarker for detecting implant related infection and a method of detecting a biomarker in a sample, said biomarker including at least part of the cnt operon and/or staphylopine. The method is suitable for diagnosing infection of a prosthetic joint and said method including the step of detecting the presence of at least part of the cnt operon and/or staphylopine in said sample.

IPC Classes  ?

  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

2.

METHODS AND COMPOSITIONS FOR DRUG RESISTANCE SCREENING

      
Application Number 18844944
Status Pending
Filing Date 2023-03-07
First Publication Date 2025-06-12
Owner
  • Quadram Institute Bioscience (United Kingdom)
  • Oxford Nanopore Technologies PLC (United Kingdom)
Inventor
  • O'Grady, Justin Joseph
  • Kay, Gemma Louise
  • Aydin, Alp

Abstract

The disclosure relates to novel primers, and their use to detect the presence of drug resistance mutations in a sample from a subject with suspected or confirmed Tuberculosis.

IPC Classes  ?

  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • C12Q 1/686 - Polymerase chain reaction [PCR]

3.

BACTERIOPHAGE COMPOSITIONS

      
Application Number GB2024051723
Publication Number 2025/008620
Status In Force
Filing Date 2024-07-03
Publication Date 2025-01-09
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Acton, Luke
  • Kingsley, Rob
  • Adriaenssens, Evelien
  • Thilliez, Gaetan

Abstract

A method of identifying and/or isolating one or more bacteriophages that display lytic activity against at least one target bacterial genus, species, or strain. The method includes the creation of a transposon mutant library using at least one bacterial strain from said genus or species and identifying the genes involved in resistance and/or susceptibility by exposing said library to at least one or more bacteriophages.

IPC Classes  ?

  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • A61K 35/76 - VirusesSubviral particlesBacteriophages
  • A61P 31/04 - Antibacterial agents
  • C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
  • C40B 40/08 - Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries

4.

METHOD OF CHARACTERISATION OF MICROBIOMES

      
Application Number GB2024051033
Publication Number 2024/218517
Status In Force
Filing Date 2024-04-19
Publication Date 2024-10-24
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)

Abstract

A method of characterising, modelling and/or profiling a microbiome composition. The method comprises the steps of subjecting metagenomic data from a plurality of microbiomes to at least one multivariate analysis of the relative abundances of bacterial genera in the metagenomic data, thereby identifying recurrent signatures. The signatures represent guilds of co-occurring bacterial genera (enterosignatures).

IPC Classes  ?

  • G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

5.

GUT BACTERIA DERIVED MICROVESICLES FOR VACCINE DELIVERY

      
Application Number 18505870
Status Pending
Filing Date 2023-11-09
First Publication Date 2024-10-10
Owner Quadram Institute Bioscience (United Kingdom)
Inventor
  • Stentz, Regis
  • Carding, Simon

Abstract

The present invention relates to a vaccine suitable for immunisation against influenza, plague or Y. pestis infection said vaccine comprising outer membrane vesicles (OMVs) and the plague vaccine including the V and/or F1 antigens of Y. pestis.

IPC Classes  ?

  • A61K 39/112 - SalmonellaShigella
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/02 - Bacterial antigens
  • A61P 37/04 - Immunostimulants
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

6.

FOODSTUFFS HAVING IMPROVED DIGESTION PROPERTIES

      
Application Number 18025099
Status Pending
Filing Date 2021-09-08
First Publication Date 2024-06-13
Owner
  • JOHN INNES ENTERPRISES LIMITED (United Kingdom)
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • IMPERIAL COLLEGE INNOVATIONS LIMITED (United Kingdom)
Inventor
  • Domoney, Claire
  • Rayner, Tracey Jane
  • Frost, Gary
  • Wilde, Pete
  • Petropoulou, Aikaterini
  • Edwards, Cathrina Hansen

Abstract

The invention relates to methods for determining if a pea variety or a product derived from that pea variety has improved digestion properties. The invention also relates to methods of improving the digestion property of a pea, as well as method of making such plants.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • A23L 33/21 - Addition of substantially indigestible substances, e.g. dietary fibres
  • C12N 15/52 - Genes encoding for enzymes or proenzymes
  • C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
  • G01N 33/02 - Food

7.

Methods and Compositions Utilising Vitamin B12 Binding

      
Application Number 18039132
Status Pending
Filing Date 2021-11-29
First Publication Date 2024-02-15
Owner Quadram Institute Bioscience (United Kingdom)
Inventor
  • Carding, Simon
  • Juodeikis, Rokas

Abstract

A composition for labelling, detection, immobilisation and/or isolation of at least one target molecule. The composition including a non-covalent affinity, coupling or binding between vitamin B12 binding protein BtuG2 and at least one bond formed between the vitamin B12 and the target molecule. The interaction between BtuG2 and vitamin B12 enables the labelling, immobilisation, isolation and/or detection of the target molecule.

IPC Classes  ?

  • G01N 33/532 - Production of labelled immunochemicals
  • G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins

8.

SATIETY PROMOTING COMPOSITIONS, FOODSTUFFS AND METHODS OF PRODUCTION THEREOF

      
Document Number 03257787
Status Pending
Filing Date 2023-05-26
Open to Public Date 2023-12-07
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • KING'S COLLEGE LONDON (United Kingdom)
Inventor
  • Bajka, Balazs
  • Edwards, Cathrina
  • Ellis, Peter

Abstract

A dietary composition and methods of producing the same wherein the fibre structure of said composition influences enteroendocrine-mediated appetite regulation. Characterised in that said composition includes intact cells from at least one legume.

IPC Classes  ?

  • A21D 2/26 - Proteins
  • A21D 2/36 - Vegetable material
  • A21D 13/045 - Products made from materials other than rye or wheat flour from leguminous plants
  • A21D 13/064 - Products with modified nutritive value, e.g. with modified starch content with modified protein content
  • A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
  • A23L 33/185 - Vegetable proteins

9.

SATIETY PROMOTING COMPOSITIONS, FOODSTUFFS AND METHODS OF PRODUCTION THEREOF

      
Application Number GB2023051406
Publication Number 2023/233135
Status In Force
Filing Date 2023-05-26
Publication Date 2023-12-07
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • KING'S COLLEGE LONDON (United Kingdom)
Inventor
  • Edwards, Cathrina
  • Ellis, Peter
  • Bajka, Balazs

Abstract

A dietary composition and methods of producing the same wherein the fibre structure of said composition influences enteroendocrine-mediated appetite regulation. Characterised in that said composition includes intact cells from at least one legume.

IPC Classes  ?

  • A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
  • A21D 2/26 - Proteins
  • A21D 2/36 - Vegetable material
  • A21D 13/045 - Products made from materials other than rye or wheat flour from leguminous plants
  • A21D 13/064 - Products with modified nutritive value, e.g. with modified starch content with modified protein content
  • A23L 33/185 - Vegetable proteins
  • A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof

10.

METHOD AND COMPOSITIONS FOR TUMORIGENESIS INHIBITION

      
Application Number GB2023051289
Publication Number 2023/223022
Status In Force
Filing Date 2023-05-16
Publication Date 2023-11-23
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor Robinson, Stephen

Abstract

Methods and compositions for substantially preventing or inhibiting tumour growth and/or angiogenesis, said method including the step of co-targeting neuropilin-1 (NRP1) and neuropilin-2 (NRP2) in endothelial cells.

IPC Classes  ?

  • A61K 31/00 - Medicinal preparations containing organic active ingredients
  • A61K 38/12 - Cyclic peptides
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61P 35/00 - Antineoplastic agents
  • C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies

11.

METHOD FOR IDENTIFYING AND OBTAINING LIVE BACTERIAL ISOLATES

      
Application Number GB2023051210
Publication Number 2023/214186
Status In Force
Filing Date 2023-05-09
Publication Date 2023-11-09
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)

Abstract

A method of isolating and/or identifying one or more strains of bacteria in a sample, said method comprising the steps of: extracting DNA from the sample, preparing a sequencing library using a long-read sequencing technique, de novo assembly of reads into one or more sequence contigs or assemblies, analysis of sequence contigs or assemblies to identify one or more conserved and/or typing gene operon sequences, analysis of sequence contigs or assemblies to identify PCR primer sites upstream of the one or more conserved and/or typing gene operon sequences, taxonomic classification of upstream PCR primer sites, and/or taxonomic classification of conserved and/or typing gene operon sequences.

IPC Classes  ?

  • C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
  • C12Q 1/6869 - Methods for sequencing
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids

12.

METHOD AND COMPOSITIONS FOR DRUG RESISTANCE SCREENING

      
Application Number 18044055
Status Pending
Filing Date 2021-08-16
First Publication Date 2023-11-02
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • O’grady, Justin Joseph
  • Kay, Gemma Louise
  • Strinden, Michael John

Abstract

The disclosure relates to novel primers, and their use to detect the presence of drug resistance mutations in a sample from a subject with suspected or confirmed Tuberculosis.

IPC Classes  ?

  • C12Q 1/6844 - Nucleic acid amplification reactions
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

13.

DETERMINATION AND QUANTIFICATION OF THE MICROBIAL COMMUNITIES AND ANTIMICROBIAL RESISTANCE GENES ON FOOD

      
Application Number GB2023050906
Publication Number 2023/194725
Status In Force
Filing Date 2023-04-05
Publication Date 2023-10-12
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Bloomfield, Samuel
  • Mather, Alison

Abstract

A method of determining and/or quantifying the microorganism communities and genes present on food, said method including the steps of; mixing a sample of said at least one foodstuff with a protease, introducing a triterpene glycoside or saponin to the mixture, introducing a DNase to the mixture, identifying and/or quantifying microorganisms and/or genes by DNA sequencing at least part of the mixture and subjecting the same to metagenomic analysis.

IPC Classes  ?

  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
  • C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

14.

METHODS AND COMPOSITIONS FOR DRUG RESISTANCE SCREENING

      
Application Number GB2023050525
Publication Number 2023/170395
Status In Force
Filing Date 2023-03-07
Publication Date 2023-09-14
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • OXFORD NANOPORE TECHNOLOGIES PLC (United Kingdom)
Inventor
  • O'Grady, Justin Joseph
  • Kay, Gemma Louise
  • Aydin, Alp

Abstract

The disclosure relates to novel primers, and their use to detect the presence of drug resistance mutations in a sample from a subject with suspected or confirmed Tuberculosis.

IPC Classes  ?

  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

15.

BIFIDOBACTERIUM AND COMPOSITIONS THEREOF FOR BREAST CANCER TREATMENT

      
Application Number GB2022053348
Publication Number 2023/118868
Status In Force
Filing Date 2022-12-21
Publication Date 2023-06-29
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Price, Christopher
  • Robinson, Stephen
  • Hall, Lindsay

Abstract

A composition for the prevention or treatment of breast cancer, said composition including any one or any combination of the bacteria from the genus Bifidobacterium.

IPC Classes  ?

16.

PulseON high protein high fibre

      
Application Number 1734722
Status Registered
Filing Date 2023-02-17
Registration Date 2023-02-17
Owner Quadram Institute Bioscience (United Kingdom)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 29 - Meat, dairy products, prepared or preserved foods
  • 30 - Basic staples, tea, coffee, baked goods and confectionery

Goods & Services

Pharmaceuticals, medical and veterinary preparations; sanitary preparations for medical purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for humans and animals; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicide; food for diabetics; food for babies; food for diabetics; food for infants; food for medically restricted diets; food supplements; food supplements consisting of amino acids; food supplements consisting of trace elements; food supplements for dietetic use; food supplements for medical purposes; food supplements for non-medical purposes; food supplements for sportsmen; food supplements for veterinary use; food supplements in liquid form; all the aforementioned excluding fish oil and derivatives thereof. Meat, fish, poultry and game; meat extracts; preserved, frozen, dried and cooked fruits and vegetables; jellies, jams, compotes; eggs; milk and milk products; edible oils and fats; food pastes made from meat; food pastes made from meat; food preparations predominantly of milk; food products made from fish. Coffee, tea, cocoa and coffee substitutes; rice; tapioca and sago; flour and preparations made from cereals; bread, pastries and confectionery; edible ices; sugar, honey, treacle; yeast, baking-powder; salt; mustard; vinegar, sauces (condiments); spices; ice; foodstuffs made from cereals; food condiment consisting primarily of ketchup and salsa; food dressings [sauces]; food flavorings [non-essential oils]; food flavorings, other than essential oils; food flavourings; food flavourings [other than essential oils]; food flavourings, other than essential oils; food leavening agents; food mixtures consisting of cereal flakes and dried fruits; food preparations based on grains; food seasonings.

17.

MEDIUM FOR PRODUCTION OF BACTERIAL EXTRACELLULAR VESICLES

      
Application Number GB2022050397
Publication Number 2022/172035
Status In Force
Filing Date 2022-02-14
Publication Date 2022-08-18
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Carding, Simon
  • Stentz, Regis
  • Juodeikis, Rokas

Abstract

Bacteroides thetaiotaomicron42422, cysteine, hemin or hematin or protoporphyrin, vitamin B12 or cobamide or methionine.

IPC Classes  ?

18.

METHOD OF TRANSPOSON INSERTION SITE SEQUENCING CAPABLE OF UNIQUELY IDENTIFYING INSERTIONS SITES WITHIN REPEATED GENETIC ELEMENTS

      
Application Number GB2022050303
Publication Number 2022/167813
Status In Force
Filing Date 2022-02-04
Publication Date 2022-08-11
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Webber, Mark
  • Turner, Keith
  • Charles, Ian
  • Yasir, Muhammad

Abstract

A method of transposon insertion sequencing (TIS) capable of resolving insertion sites in or around repeat elements, said method including the steps of; preparing a pool or library of mutant cells by introduction or insertion of one or more transposon sequences, extraction of DNA from said cells, DNA fragmentation, DNA amplification, and characterised in that the amplified DNA is sequenced by a long-read sequencing method.

IPC Classes  ?

  • C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12Q 1/6869 - Methods for sequencing

19.

METHODS AND COMPOSITIONS FOR ANTIBIOTIC POTENTIATION

      
Application Number GB2022050060
Publication Number 2022/153045
Status In Force
Filing Date 2022-01-12
Publication Date 2022-07-21
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)

Abstract

A method of potentiating or inducing antibiotic efficacy in one or more compositions or compounds, said method including the step of inducing a substantially cell wall deficient (CWD) state in a bacteria by exposure to at least one antibiotic before and/or in combination with said one or more compositions or compounds.

IPC Classes  ?

  • A61K 31/05 - Phenols
  • A61K 31/191 - Acyclic acids having two or more hydroxy groups, e.g. gluconic acid
  • A61K 31/345 - Nitrofurans
  • A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
  • A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
  • A61K 31/47 - QuinolinesIsoquinolines
  • A61K 31/4745 - QuinolinesIsoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
  • A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
  • A61K 31/665 - Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
  • A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61P 31/04 - Antibacterial agents

20.

DELIVERY OF BACTERIA-DERIVED OUTER MEMBRANE VESICLES

      
Application Number 17595330
Status Pending
Filing Date 2020-05-15
First Publication Date 2022-06-09
Owner Quadram Institute Bioscience (United Kingdom)
Inventor
  • Carding, Simon
  • Stentz, Regis

Abstract

Pharmaceutical compositions and preparation including outer membrane vesicles (OMVs) and at least one pharmaceutically acceptable carrier wherein said OMVs are native OMVs produced by the Gram-negative commensal bacteria Bacteroides.

IPC Classes  ?

  • A61K 39/02 - Bacterial antigens
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

21.

PRODUCTION AND MODIFICATION OF BACTERIAL MICROCOMPARTMENTS AND USE THEREOF

      
Application Number GB2021053173
Publication Number 2022/118040
Status In Force
Filing Date 2021-12-03
Publication Date 2022-06-09
Owner
  • UNIVERSITY OF KENT (United Kingdom)
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor Warren, Martin

Abstract

pdupdu) shell proteins that include two hexameric and one pentameric shell protein.

IPC Classes  ?

  • C07K 14/24 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
  • C12N 9/88 - Lyases (4.)
  • C12N 15/70 - Vectors or expression systems specially adapted for E. coli

22.

METHODS AND COMPOSITIONS UTILISING VITAMIN B12 BINDING

      
Application Number GB2021053106
Publication Number 2022/112795
Status In Force
Filing Date 2021-11-29
Publication Date 2022-06-02
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Carding, Simon
  • Stenz, Regis

Abstract

12121212 enables the labelling, immobilisation, isolation and/or detection of the target molecule.

IPC Classes  ?

  • G01N 33/532 - Production of labelled immunochemicals
  • G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
  • G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins

23.

COMPOSITIONS AND METHODS FOR EXTRACELLULAR VESICLE DRUG DELIVERY

      
Application Number GB2021053105
Publication Number 2022/112794
Status In Force
Filing Date 2021-11-29
Publication Date 2022-06-02
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Carding, Simon
  • Stenz, Regis

Abstract

A method of producing a vaccine, said method including the steps of; isolating at least one microbial and/or viral protein or antigen, bonding the microbial and/or viral protein or antigen to vitamin B12 (vitB12) and wherein the vitB12 attached proteins or antigens are mixed with outer membrane vesicles (OMVs).

IPC Classes  ?

24.

IDENTIFICATION OF ANTIBIOTIC SYNERGISTIC TARGETS

      
Application Number GB2021052668
Publication Number 2022/079440
Status In Force
Filing Date 2021-10-14
Publication Date 2022-04-21
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Webber, Mark
  • Turner, Keith
  • Charles, Ian
  • Yasir, Muhammad
  • Bastkowski, Sarah

Abstract

A method of identifying genes, or proteins encoded by said genes, in a microbe that contribute or influence antimicrobial sensitivity, including the steps of; producing a transposon mutant library with sequencing of all transposon–chromosome insertion junction sites in parallel, identifying primary target genes or gene products within the mutant library that contribute to microbe sensitivity to a first antimicrobial compound by subjecting said mutants to growth or survival under a number of test conditions, and wherein secondary target genes or gene products are identified from the library or primary target genes or gene products, that are sensitive to at least one second compound.

IPC Classes  ?

  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

25.

Gut bacteria derived microvesicles for vaccine delivery

      
Application Number 17309067
Grant Number 12005106
Status In Force
Filing Date 2019-10-22
First Publication Date 2022-04-07
Grant Date 2024-06-11
Owner Quadram Institute Bioscience (United Kingdom)
Inventor
  • Stentz, Regis
  • Carding, Simon

Abstract

Y. pestis.

IPC Classes  ?

  • A61K 39/02 - Bacterial antigens
  • A61K 39/112 - SalmonellaShigella
  • A61P 37/04 - Immunostimulants
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

26.

FOODSTUFFS HAVING IMPROVED DIGESTION PROPERTIES

      
Application Number EP2021074674
Publication Number 2022/053494
Status In Force
Filing Date 2021-09-08
Publication Date 2022-03-17
Owner
  • JOHN INNES ENTERPRISES LIMITED (United Kingdom)
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • IMPERIAL COLLEGE INNOVATIONS LIMITED (United Kingdom)
Inventor
  • Domoney, Claire
  • Rayner, Tracey Jane
  • Frost, Gary
  • Wilde, Pete
  • Petropoulou, Aikaterini
  • Edwards, Cathrina Hansen

Abstract

The invention relates to methods for determining if a pea variety or a product derived from that pea variety has improved digestion properties. The invention also relates to methods of improving the digestion property of a pea, as well as method of making such plants.

IPC Classes  ?

  • A01H 6/54 - Leguminosae or Fabaceae, e.g. soybean, alfalfa or peanut
  • A01H 5/08 - Fruits
  • A01H 1/00 - Processes for modifying genotypes
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C12N 9/10 - Transferases (2.)

27.

METHOD AND COMPOSITIONS FOR DRUG RESISTANCE SCREENING

      
Application Number GB2021052121
Publication Number 2022/049365
Status In Force
Filing Date 2021-08-16
Publication Date 2022-03-10
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • O'Grady, Justin Joseph
  • Kay, Gemma Louise
  • Strinden, Michael John

Abstract

The disclosure relates to novel primers, and their use to detect the presence of drug resistance mutations in a sample from a subject with suspected or confirmed Tuberculosis.

IPC Classes  ?

  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

28.

Engineering gut commensal bacteria to express heterologous proteins in their outer membrane vesicles (OMVS) for delivery to the GI-tract

      
Application Number 17316219
Grant Number 12251433
Status In Force
Filing Date 2021-05-10
First Publication Date 2021-09-02
Grant Date 2025-03-18
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • UEA ENTERPRISES LIMITED (United Kingdom)
Inventor
  • Stentz, Regis Gabriel
  • Carding, Simon Richard

Abstract

This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.

IPC Classes  ?

  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
  • A61K 35/74 - Bacteria
  • A61K 39/02 - Bacterial antigens
  • A61K 39/112 - SalmonellaShigella
  • A61P 31/04 - Antibacterial agents
  • C12N 1/20 - BacteriaCulture media therefor
  • C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
  • C12N 15/52 - Genes encoding for enzymes or proenzymes
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

29.

SIALIC ACID TRANSPORTER PROTEINS AS BIOMARKERS AND DRUG TARGETS

      
Application Number 17252619
Status Pending
Filing Date 2019-06-17
First Publication Date 2021-08-19
Owner Quadram Institute Bioscience (United Kingdom)
Inventor
  • Juge, Nathalie
  • Bell, Andrew
  • Walshaw, John

Abstract

A method of identifying, monitoring and/or diagnosing mucosal bacterial presence or infection, said method including the step of detecting at least part of a sialic acid transporter protein encoded by Ruminococcus gnavus (R. gnavus) ATCC 29149 Nan cluster. In addition, a method of inhibition of the growth of bacterium, said method including the step of inhibition of a sialic acid transporter protein is included.

IPC Classes  ?

  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
  • C12Q 1/686 - Polymerase chain reaction [PCR]
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

30.

Delivery of Bacteria-Derived Outer Membrane Vesicles

      
Application Number GB2020051204
Publication Number 2020/229846
Status In Force
Filing Date 2020-05-15
Publication Date 2020-11-19
Owner QUADRAM INSITITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Carding, Simon
  • Stentz, Regis

Abstract

BacteroidesBacteroides.

IPC Classes  ?

  • A61K 39/02 - Bacterial antigens
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

31.

GENOMIC ANALYSIS

      
Application Number GB2019053128
Publication Number 2020/095035
Status In Force
Filing Date 2019-11-05
Publication Date 2020-05-14
Owner
  • EARLHAM INSTITUTE (United Kingdom)
  • UNIVERSITY OF EAST ANGLIA (United Kingdom)
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Korcsmaros, Tamas
  • Brooks, Johanne
  • Carding, Simon R.

Abstract

A method of identifying contribution of a genomic variation to a phenotypic feature is disclosed. The method comprises determining a degree of a genomic variation (51; Fig. ) in each individual in a set of individuals and recording the degree of genomic variation in each individual in a database, for example, in a first table (6). The method comprises determining a location of the genomic variation to allow determination, by virtue of the location, of whether the genomic variation affects a gene product directly and/or regulates production of a gene product (53, 54; Fig. 5). The method comprises determining a first gene (51; Fig. 5) affected by the genomic variation. When the genomic variation affects a gene product directly, recording the gene, in the coding sequence of which the genomic variation is located, as the first gene, for example, in a second table (7). When the genomic variation regulates the production of a gene product, recording the gene, in the promoter region or other regulatory region of which the genomic variation is located, as the first gene. The method comprises determining an outcome of the genomic variation on the first gene and recording the outcome of the genomic variation in the database, for example, in the second table and determining the presence or absence of one or more other gene products (i) interacting with the first gene, (ii) encoded by the first gene; and/or (iii) regulating the first gene and, if present, recording the identity of the gene encoding the one or more other gene products in the database as the second gene, for example, in the second table.

IPC Classes  ?

  • G16B 5/00 - ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
  • G16B 20/20 - Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection

32.

GUT BACTERIA DERIVED MICROVESICLES FOR VACCINE DELIVERY

      
Application Number GB2019053007
Publication Number 2020/084295
Status In Force
Filing Date 2019-10-22
Publication Date 2020-04-30
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)

Abstract

The present invention relates to a vaccine suitable for immunisation against influenza, plague or Y. pestis infection said vaccine comprising outer membrane vesicles (OMVs) and the plague vaccine including the V and/or F1 antigens of Y. pestis.

IPC Classes  ?

  • A61P 37/04 - Immunostimulants
  • A61K 39/02 - Bacterial antigens
  • C12R 1/01 - Bacteria or actinomycetales
  • A61K 39/112 - SalmonellaShigella
  • A61K 39/12 - Viral antigens
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

33.

SIALIC ACID TRANSPORTER PROTEINS AS BIOMARKERS AND DRUG TARGETS

      
Application Number GB2019051691
Publication Number 2019/239164
Status In Force
Filing Date 2019-06-17
Publication Date 2019-12-19
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)

Abstract

uminococcus gnavusgnavusgnavus) ATCC 29149 Nan cluster. In addition, a method of inhibition of the growth of bacterium, said method including the step of inhibition of a sialic acid transporter protein is included.

IPC Classes  ?

  • C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • A61K 38/00 - Medicinal preparations containing peptides

34.

Engineering gut commensal bacteria to express heterologous proteins in their outer membrane vesicles (OMVs) for delivery to the GI-tract

      
Application Number 16086906
Grant Number 11000581
Status In Force
Filing Date 2017-04-28
First Publication Date 2019-04-04
Grant Date 2021-05-11
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • UEA ENTERPRISES LIMITED (United Kingdom)
Inventor
  • Stentz, Regis Gabriel
  • Carding, Simon Richard

Abstract

This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • A61K 39/02 - Bacterial antigens
  • C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
  • C12N 1/20 - BacteriaCulture media therefor
  • A61K 35/74 - Bacteria
  • A61K 39/112 - SalmonellaShigella
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • A61P 31/04 - Antibacterial agents
  • C12N 15/52 - Genes encoding for enzymes or proenzymes
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 38/00 - Medicinal preparations containing peptides

35.

Intramolecular Trans-Sialidase

      
Application Number 16075485
Status Pending
Filing Date 2017-02-06
First Publication Date 2019-02-07
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Juge, Nathalie
  • Monestier, Marie Maguelonne
  • Field, Robert Andrew

Abstract

The present invention relates to an intramolecular trans-sialidase (IT-sialidase) enzyme from Ruminococcus gnavus and fragments thereof. It also relates to methods of production of the IT-sialidase or its fragments, in addition to uses of the IT-sialidase, its fragments, or compositions comprising the IT-sialidase. One of the uses of the IT-sialidase or its fragments encompassed by the present invention is a method for production of 2,7-anhydro sialic acid derivatives. Further uses of the IT-sialidase enzyme include the therapeutic and prophylactic treatment of infections and respiratory conditions.

IPC Classes  ?

  • A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
  • A23L 29/00 - Foods or foodstuffs containing additivesPreparation or treatment thereof
  • A61K 38/47 - Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
  • A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
  • A61P 31/04 - Antibacterial agents
  • C12N 9/26 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on alpha-1, 4-glucosidic bonds, e.g. hyaluronidase, invertase, amylase
  • C12R 1/225 - Lactobacillus
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

36.

ENGINEERING GUT COMMENSAL BACTERIA TO EXPRESS HETEROLOGOUS PROTEINS IN THEIR OUTER MEMBRANE VESICLES (OMVS) FOR DELIVERY TO THE GI-TRACT

      
Document Number 03003561
Status Pending
Filing Date 2017-04-28
Open to Public Date 2017-11-02
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • UEA ENTERPRISES LIMITED (United Kingdom)
Inventor
  • Stentz, Regis Gabriel
  • Carding, Simon Richard

Abstract

This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.

IPC Classes  ?

  • A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/02 - Bacterial antigens
  • A61K 39/106 - VibrioCampylobacter
  • A61K 39/12 - Viral antigens
  • C12N 1/20 - BacteriaCulture media therefor
  • C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

37.

ENGINEERING GUT COMMENSAL BACTERIA TO EXPRESS HETEROLOGOUS PROTEINS IN THEIR OUTER MEMBRANE VESICLES (OMVS) FOR DELIVERY TO THE GI-TRACT

      
Application Number GB2017051199
Publication Number 2017/187190
Status In Force
Filing Date 2017-04-28
Publication Date 2017-11-02
Owner
  • QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
  • UEA ENTERPRISES LIMITED (United Kingdom)
Inventor
  • Stentz, Regis Gabriel
  • Carding, Simon Richard

Abstract

This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.

IPC Classes  ?

  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • C12N 1/20 - BacteriaCulture media therefor
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
  • C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
  • A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/02 - Bacterial antigens
  • A61K 39/106 - VibrioCampylobacter
  • A61K 39/12 - Viral antigens

38.

S-METHYLCYSTEINE SULFOXIDE FOR PROSTATE CANCER PREVENTION AND TREATMENT

      
Application Number GB2017050838
Publication Number 2017/163081
Status In Force
Filing Date 2017-03-24
Publication Date 2017-09-28
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Mithen, Richard
  • Melchini, Antonietta
  • Traka, Maria

Abstract

The present invention relates to S-methylcysteine sulfoxide and compositions thereof for use in the treatment or prevention of prostate cancer. It also relates to analogues, derivatives or metabolites of S-methylcysteine sulfoxide for use in the treatment or prevention of prostate cancer. Compositions of S-methylcysteine sulfoxide or its analogues, derivatives or metabolites may be provided for oral consumption, for example as a pharmaceutical composition, a medicament or a food composition.

IPC Classes  ?

  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 31/7028 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 36/31 - Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
  • A61P 35/00 - Antineoplastic agents

39.

NMR METHOD OF DETECTING A MARKER IN A COFFEE PRODUCT

      
Application Number GB2017050672
Publication Number 2017/153783
Status In Force
Filing Date 2017-03-13
Publication Date 2017-09-14
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Kemsley, Evelyn Katherine
  • Defernez, Marianne
  • Watson, Andrew David

Abstract

A method for detecting a marker in a sample is provided. The method comprises adding solvent to the coffee to prepare a sample; scanning the sample using low-field NMR spectroscopy to generate a spectral fingerprint, and; analysing the spectral fingerprint, wherein the presence of a fingerprint unique to the marker indicates the presence of the marker, wherein the marker is caffeine or 16-OMC.

IPC Classes  ?

  • G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
  • G01R 33/46 - NMR spectroscopy

40.

INTRAMOLECULAR TRANS-SIALIDASE

      
Application Number GB2017050291
Publication Number 2017/134466
Status In Force
Filing Date 2017-02-06
Publication Date 2017-08-10
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
Inventor
  • Juge, Nathalie
  • Monestier, Marie Maguelonne
  • Field, Robert Andrew

Abstract

The present invention relates to an intramolecular frans-sialidase (IT-sialidase) enzyme from Ruminococcus gnavus and fragments thereof. It also relates to methods of production of the IT- sialidase or its fragments, in addition to uses of the IT-sialidase, its fragments, or compositions comprising the IT-sialidase. One of the uses of the IT-sialidase or its fragments encompassed by the present invention is a method for production of 2,7-anhydro sialic acid derivatives. Further uses of the IT-sialidase enzyme include the therapeutic and prophylactic treatment of infections and respiratory conditions.

IPC Classes  ?

  • A61K 31/7012 - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
  • A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

41.

QUADRAM

      
Application Number 179586200
Status Registered
Filing Date 2016-08-15
Registration Date 2022-01-28
Owner QUADRAM INSTITUTE BIOSCIENCE (United Kingdom)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 16 - Paper, cardboard and goods made from these materials
  • 29 - Meat, dairy products, prepared or preserved foods
  • 30 - Basic staples, tea, coffee, baked goods and confectionery
  • 31 - Agricultural products; live animals
  • 32 - Beers; non-alcoholic beverages
  • 33 - Alcoholic beverages other than beer
  • 40 - Treatment of materials; recycling, air and water treatment,
  • 41 - Education, entertainment, sporting and cultural services
  • 42 - Scientific, technological and industrial services, research and design
  • 43 - Food and drink services, temporary accommodation
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Chemical, biochemical and biological, reagents and preparations, other than for medical and veterinary purposes, namely, bacterial cultures for addition to food and beverage products, and bacterial cultures for use in food and beverage manufacturing; chemical, biochemical and biological, reagents and preparations, other than for medical and veterinary purposes, namely, chemical and biochemical additives for use in the manufacture of food and beverages; chemical, biochemical and biological substances, reagents and preparations used in tests and for testing other than for medical or for veterinary purposes, namely, diagnostic reagents for scientific research use that test for contaminants in food and beverages; chemical, biochemical or biological substances, reagents or preparations for in vitro or in vivo tests, other than for medical and veterinary purposes, namely, diagnostic reagents for in vitro use in biochemistry and microbiology; biological reaction testing devices, namely, laboratory assay kits (2) Chemical, biochemical and biological reagents and preparations for medical and for veterinary purposes, namely, reagents and biochemical preparations that originate in, and are transported through the gut for the detection and treatment of viral, metabolic, musculoskeletal, cardiovascular, genitourinary, central nervous system, endocrinological, immunological, obstetrical, gynaecological, respiratory, neurological, gastrointestinal, hormonal, dermatological and psychiatric related diseases and disorders namely diagnostic biomarker reagents, diagnostic reagents, and in vitro and in vivo diagnostic preparations for medical and veterinary purposes; chemical and biochemical preparations for diagnostic use for medical and veterinary purposes, namely, biochemical preparations that originate in, and are transported through the gut for the diagnosis of viral, metabolic, musculoskeletal, cardiovascular, genitourinary, central nervous system, endocrinological, immunological, obstetrical, gynaecological, respiratory, neurological, gastrointestinal, hormonal, dermatological and psychiatric related diseases and disorders by absorption and transport of said preparations through the gut namely diagnostic biomarker reagents, diagnostic reagents, and in vitro and in vivo diagnostic preparations for medical and veterinary purposes; diagnostic agents of biological origin in the human and animal gut for use in medical and veterinary diagnosis, namely, diagnostic biomarker reagents for medical and veterinary purposes; chemical, biochemical and biological substances, reagents and preparations used in test and for testing for medical and for veterinary purposes, namely, diagnostic reagents for medical use and diagnostic reagents for veterinary use; chemical , biochemical or biological substances, reagents or preparations that originate in, and are transported through the gut for in vitro or in vivo tests for medical and for veterinary purposes, namely, in vitro and in vivo diagnostic preparations for medical and veterinary purposes; dietetic food and substances adapted for medical or veterinary use, namely, food for babies; dietary supplements for humans, namely, dietary supplements for general health and well-being; dietary supplements for and animals, namely, vitamin and mineral dietary supplements for animals; vitamin and mineral food supplements; health supplements, namely, nutritional supplements for general health and well-being; vitamins, minerals and other nutraceuticals, namely, vitamin and mineral dietary supplements; pre-biotics, namely, prebiotic preparations for medical purposes to help maintain a natural balance of flora in the digestive system; pro-biotics, namely, probiotic preparations for medical purposes to help maintain a natural balance of flora in the digestive system; microorganisms for use in food and beverages, namely, prebiotic preparations and probiotic preparations for use in food and beverages for medical purposes to help maintain a natural balance of flora in the digestive system; fungicides; herbicides (3) Computers and computer programs for chemical, biochemical and biological analysis of data in the field of microbiology and food science; software for the collection and storage of analytical data in the fields of bacteriological analysis, biochemical analysis, chemical analysis, and food science; diagnostic testing equipment, namely, incubators for bacteria cultures, laboratory test tubes, pipettes, chromatography columns for laboratory use, and laboratory centrifuges; forensic testing equipment, namely, mass spectrometers, biological microscopes, and chromatography apparatus for laboratory use; hygiene testing equipment, namely, test strips impregnated with reagents for testing the sterility of medical, surgical and veterinary equipment; food testing equipment, namely, laboratory thermometers, digital pH meters, refractometers, mass spectrometers, spectrophotometers, and laboratory instruments for the detection of pathogens and toxins in food samples for research use; instruments and measuring apparatus for physical testing, namely, medical scales; biological and microbiological testing equipment, namely, petri dishes, drying ovens for laboratory use, and electrophoresis units; downloadable electronic publications in the fields of health, hygiene, nutrition, diet and food; (4) Surgical instruments for monitoring chemical, biochemical and biological reaction and systems; veterinary instruments for monitoring chemical, biochemical and biological reaction and systems; surgical instruments for the preparation, screening and analysis of samples and specimens; veterinary instruments for the preparation, screening and analysis of samples and specimens; surgical genetic testing equipment, namely, thermal cyclers for use in genetic testing for surgical purposes; medical genetic testing equipment, namely, thermal cyclers for use in genetic testing for medical purposes; veterinary genetic testing equipment, namely, thermal cyclers for use in genetic testing for veterinary purposes; forensic testing equipment for medical purposes, namely, gas chromatography apparatus for forensic medical purposes, thermal cyclers for use in genetic testing for forensic medical purposes, thermometers for forensic medical purposes, and mass spectrometers for forensic medical purposes; surgical diagnostic testing equipment, namely, magnetic resonance imaging (MRI) diagnostic apparatus for surgical purposes and ultrasonic medical diagnostic apparatus for surgical purposes; medical diagnostic testing equipment, namely, magnetic resonance imaging (MRI) diagnostic apparatus for medical purposes and ultrasonic medical diagnostic apparatus for medical purposes; veterinary diagnostic testing equipment, namely, magnetic resonance imaging (MRI) diagnostic apparatus for veterinary purposes and ultrasonic medical diagnostic apparatus for veterinary purposes (5) Printed matter, namely, brochures, flyers, and magazines; printed publications, namely, medical publications and printed publications in the fields of microbiology, gastrointestinal health, diet and nutrition; (6) Meat, fish, poultry and game; meat extracts; preserved, frozen, dried and cooked fruits and vegetables; jellies, jams, compotes; eggs; milk and milk products; edible oils and fats; food products made from the aforesaid ingredients, namely, yogurt and dairy beverages; (7) Coffee, tea, cocoa and artificial coffee; rice; tapioca and sago; flour and preparations made from cereals, namely, rolled oats and wheat, oat flakes, barley meal, and wheat germ; bread, pastries and confectionery, namely, sugar confectionery, chocolate confectionery, almond confectionery and peanut confectionery; edible ices; sugar, honey, treacle; yeast, yeast cultures; baking powder; salt; mustard, vinegar, sauces, namely, ketchup, mayonnaise, relishes, hot sauce, and chutney condiments; spices; ices; food products made from the aforesaid ingredients, namely, dough and breakfast cereals; (8) Agricultural, horticultural and forestry products, namely, bulbs, spores, spawn and seeds for agricultural purposes, and bulbs and seeds horticultural purposes; fresh fruits and vegetables; natural plants and flowers; foodstuffs for animals, namely, animal feed; malt for brewing and distilling; raw and unprocessed grains and unprocessed seeds for agricultural purposes (9) Beers; mineral and aerated waters and other non-alcoholic beverages, namely, soft drinks; fruit beverages and fruit juices; syrups for making beverages; powders and concentrates used in the preparation of fruit-based drinks, soft drinks and effervescing beverages; (10) Alcoholic beverages (except beers), namely, wine, brandy, gin, rum, tequila, vodka, whisky, and liqueurs; (1) Treatment of waste water; treatment of industrial waste and food waste; advisory, information and consultancy services in the fields of the treatment of waste water, industrial waste and food waste; (2) Instruction services, namely, instruction in the fields of health, hygiene, nutrition, diet and food; educational services in the fields of health, hygiene, nutrition, diet and food; educational services in the fields of food technology; information exchange services between scientists, researchers, commercial and industrial entities namely educational, teaching and training services; providing conference facilities; providing on-line electronic publications, not downloadable, in the fields of health, hygiene, nutrition, diet and food; publication of electronic books and journals on-line; publication of texts, other than publicity texts; teaching nutrition; writing of electronic books, magazines, and journals; advisory, information and consultancy services in the fields of providing instruction and educational services in the fields of health, hygiene, nutrition, diet, food, and food technology; advisory, information and consultancy services in the field of information exchange services between scientists, researchers, commercial and industrial entities namely educational, teaching and training services; advisory, information and consultancy services in the field of publication of texts, other than publicity texts and writing of electronic books, magazines, and journals; (3) Analytic laboratory services, namely, bacteriological analysis, chemical analysis and biochemical analysis; food intolerance, food analysis, food technology, food science and food safety studies; contract research, namely, research for others in the fields of molecular chemistry and molecular biology; computerized food analysis services, namely, chemical, biochemical and bacteriological analysis of food using computer systems; provision of scientific information on food safety testing; quality control in the field of hygiene; research in the fields of health, hygiene, nutrition, diet and food; research into the treatment of waste materials; research into the treatment of biomass; information exchange services between scientists, researchers, commercial and industrial entities namely industrial analysis and research projects, provision of scientific, technological and research information; laboratory research in the fields of chemistry, biochemistry, microbiology, and food science; laboratory testing services, namely, laboratory testing of materials, medical laboratory services and veterinary laboratory services; pharmaceutical research and development services; project studies, namely, conducting scientific feasibility studies; mathematical research services, namely, statistical analysis of data from scientific studies in the fields of chemistry, biochemistry, microbiology, and food science ; preparation of reports relating to technical and scientific research, namely, technical writing of reports in the fields of chemistry, biochemistry, microbiology, and food science; provision of scientific information in the fields of chemistry, biochemistry, microbiology and food science; creating, testing, implementing, developing, maintaining, updating, and providing advisory and consultancy services in the fields of computer programs, computer networks, websites, web pages; advisory, information and consultancy services related to the aforesaid, namely, computer software consulting; (4) Advisory services in the fields of health, hygiene, nutrition and diet; consultancy and counselling services in the fields of health, hygiene, nutrition and diet; provision of information in the fields of health, hygiene, nutrition and diet; professional consultancy in the fields of health, hygiene, nutrition and diet

42.

QUADRAM

      
Application Number 015106487
Status Registered
Filing Date 2016-02-14
Registration Date 2016-12-13
Owner Quadram Institute Bioscience (United Kingdom)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 16 - Paper, cardboard and goods made from these materials
  • 29 - Meat, dairy products, prepared or preserved foods
  • 30 - Basic staples, tea, coffee, baked goods and confectionery
  • 31 - Agricultural products; live animals
  • 32 - Beers; non-alcoholic beverages
  • 33 - Alcoholic beverages other than beer
  • 40 - Treatment of materials; recycling, air and water treatment,
  • 41 - Education, entertainment, sporting and cultural services
  • 42 - Scientific, technological and industrial services, research and design
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Chemical, biochemical and biological, reagents and preparations, other than for medical or for veterinary purposes, chemical, biochemical and biological substances, reagents and preparations used in tests and for testing other than for medical or for veterinary purposes; chemical, biochemical or biological substances, reagents or preparations for in vitro or in vivo tests (other than for medical or veterinary purposes). Chemical, biochemical and biological reagents and preparations for medical or for veterinary purposes; chemical and biochemical preparations for diagnostic use for medical or veterinary purposes; diagnostic agents of biological origin for use in medical or veterinary diagnosis; chemical, biochemical and biological substances, reagents and preparations used in test and for testing for medical or for veterinary purposes; chemical, biochemical or biological substances, reagents or preparations for in vitro or in vivo tests for medical or for veterinary purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for humans and animals; food supplements; health supplements; vitamins, minerals and other nutraceuticals; prebiotics, probiotics; microorganisms for use in food and beverages; fungicides; herbicides. Scientific instruments; computers and computer programs; software for use in data capturing and storage; detectors for scientific use; diagnostic testing equipment; forensic testing equipment; hygiene testing equipment; food testing equipment; automated testing apparatus; apparatus and instruments for analysing biological reactions (for laboratory and scientific use); biological reaction testing devices; biological reaction analysers; instruments and measuring apparatus for physical testing, biological and microbiological testing equipment; downloadable publications. Surgical apparatus and instruments for monitoring chemical, biochemical and biological reaction and systems; veterinary apparatus and instruments for monitoring chemical, biochemical and biological reaction and systems; surgical apparatus and instruments for the preparation, screening and analysis of samples and specimens; veterinary apparatus and instruments for the preparation, screening and analysis of samples and specimens; surgical genetic testing equipment; medical genetic testing equipment; veterinary genetic testing equipment; forensic testing equipment for medical purposes; hygiene testing equipment; surgical, diagnostic testing equipment; medical diagnostic testing equipment; veterinary diagnostic testing equipment. Printed matter; printed publications. Meat, fish, poultry and game; meat extracts; preserved, frozen, dried and cooked fruits and vegetables; jellies, jams, compotes; eggs; milk and milk products; edible oils and fats; food products made from the aforesaid ingredients. Coffee, tea, cocoa and artificial coffee; rice; tapioca and sago; flour and preparations made from cereals; bread, pastries and confectionery; edible ices; sugar, honey, treacle; yeast, yeast cultures; baking powder; salt; mustard, vinegar, sauces (condiments); spices; ices; food products made the aforesaid ingredients. Agricultural, horticultural and forestry products; fresh fruits and vegetables; natural plants and flowers; foodstuffs for animals; malt; raw and unprocessed grains and seeds. Beers; mineral and aerated waters and other non-alcoholic beverages; fruit beverages and fruit juices; syrups and other preparations for making beverages. Alcoholic beverages (except beers). Treatment of waste materials; treatment of industrial waste including food waste; advisory, information and consultancy services related to the aforesaid. Instruction services; educational services relating to health, hygiene, nutrition, diet and food; educational services relating to food technology; instruction in diet (non medical); provision of training relating to health, hygiene, diet and food; training services relating to health hygiene, nutrition, diet and food; information exchange services between scientists, researchers, commercial and industrial entities namely educational, teaching and training services; providing conference facilities; providing on-line electronic publications, not downloadable; publication of electronic books and journals on-line; publication of texts, other than publicity texts; teaching; texts (writing of-), other than publicity texts; tuition; advisory, information and consultancy services related to the aforesaid. Scientific and- industrial research and- design services; analytic laboratory services; food intolerance, food analysis, food technology, food science and food safety studies; contract research services relating to molecular sciences; computerized food analysis services; provision of information on food safety; quality control relating to hygiene; research relating to health, hygiene, nutrition, diet and food; research into the treatment of waste materials; research into the treatment of biomass; information exchange services between scientists, researchers, commercial and industrial entities namely industrial analysis and research projects, provision of scientific, technological and research information; laboratory research; laboratory testing services; scientific and technological services and research and design thereto; pharmaceutical research and development services; project studies (technical -); mathematical research services; preparation of reports relating to technical or scientific research; provision of information relating to scientific or technical research;  creating, testing, implementing, developing, maintaining, updating, and providing advisory and consultancy services in relation to computer programs, computer networks, websites, web pages and mobile apps; advisory, information and consultancy services related to the aforesaid. Advisory services relating to health, hygiene, nutrition and diet; consultancy and counselling services relating to health, hygiene, nutrition and diet; provision of information relating to health, hygiene, nutrition and diet; professional consultancy relating to health, hygiene, nutrition and diet.