Flexopharm Brain GMBH & Co. KG

Germany

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IP Type
        Patent 8
        Trademark 4
Jurisdiction
        World 7
        United States 5
Date
2020 4
Before 2020 8
IPC Class
A61K 31/19 - Carboxylic acids, e.g. valproic acid 8
A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids 4
A61K 9/20 - Pills, lozenges or tablets 4
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate 4
A61P 37/02 - Immunomodulators 4
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NICE Class
05 - Pharmaceutical, veterinary and sanitary products 4
01 - Chemical and biological materials for industrial, scientific and agricultural use 2

1.

Supporting immunomodulatory agent

      
Application Number 16915628
Grant Number 11471432
Status In Force
Filing Date 2020-06-29
First Publication Date 2020-10-15
Grant Date 2022-10-18
Owner Flexopharm Brain GMBH & Co. KG (Germany)
Inventor
  • Gold, Ralf
  • Haghikia, Aiden
  • Matthes, Ulrich

Abstract

8 carboxylic acids, physiologically acceptable salts and/or esters thereof, and one or more fumaric acid esters and/or salts thereof. The combination being particularly useful in the treatment of psoriasis and multiple sclerosis.

IPC Classes  ?

  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
  • A61K 31/25 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
  • A61P 17/06 - Antipsoriatics
  • A61P 37/02 - Immunomodulators
  • A61K 31/714 - Cobalamins, e.g. cyanocobalamin, vitamin B12
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/225 - Polycarboxylic acids

2.

Supporting immunomodulatory agent

      
Application Number 16891997
Grant Number 11865091
Status In Force
Filing Date 2020-06-03
First Publication Date 2020-09-17
Grant Date 2024-01-09
Owner Flexopharm Brain GMBH & Co. KG (Germany)
Inventor
  • Gold, Ralf
  • Haghikia, Aiden
  • Linker, Ralf

Abstract

8 alkyl alcohols.

IPC Classes  ?

  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A23L 33/12 - Fatty acids or derivatives thereof
  • A23L 33/16 - Inorganic salts, minerals or trace elements
  • A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/20 - Pills, lozenges or tablets
  • A23L 33/10 - Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
  • A23L 33/115 - Fatty acids or derivatives thereof; Fats or oils
  • A61K 9/00 - Medicinal preparations characterised by special physical form

3.

AGENT FOR USE IN THE TREATMENT OF PATIENTS SUFFERING FROM END STAGE RENAL DISEASE-RELATED SYSTEMIC INFLAMMATORY SYMPTOMS AND OXIDATIVE STRESS

      
Application Number EP2019075212
Publication Number 2020/058424
Status In Force
Filing Date 2019-09-19
Publication Date 2020-03-26
Owner FLEXOPHARM BRAIN GMBH & CO. KG (Germany)
Inventor
  • Heidland, August
  • Di Iorio, Biagio
  • Marzocco, Stefania

Abstract

The invention relates to an agent for use in the treatment of patients suffering from systemic inflammatory symptoms and oxidative stress caused by end stage renal disease. Said agent contains a short-chain fatty acid having 3 to 6 carbon atoms or a physiologically acceptable derivative thereof as an active ingredient.

IPC Classes  ?

  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61P 13/12 - Drugs for disorders of the urinary system of the kidneys

4.

Agent for use in the treatment of dyslipidemia

      
Application Number 16491739
Grant Number 11602510
Status In Force
Filing Date 2018-03-09
First Publication Date 2020-01-30
Grant Date 2023-03-14
Owner Flexopharm Brain GMBH & Co. KG (Germany)
Inventor Haghikia, Aiden

Abstract

The invention relates to an agent for use in the prophylaxis or treatment of dyslipidemia, in particular for the treatment of excessive/elevated LDL levels, containing propionic acid or a physiologically acceptable propionic acid derivative.

IPC Classes  ?

  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61P 3/06 - Antihyperlipidemics
  • A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

5.

Supporting immunomodulatory agent

      
Application Number 15769282
Grant Number 10695305
Status In Force
Filing Date 2016-07-08
First Publication Date 2018-10-25
Grant Date 2020-06-30
Owner FLEXOPHARM BRAIN GMBH & CO. KG (Germany)
Inventor
  • Gold, Ralf
  • Haghikia, Aiden
  • Matthes, Ulrich

Abstract

8 carboxylic acids, physiologically acceptable salts and/or esters thereof, and one or more fumaric acid esters and/or salts thereof. The combination being particularly useful in the treatment of psoriasis and multiple sclerosis.

IPC Classes  ?

  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
  • A61K 31/25 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
  • A61P 17/06 - Antipsoriatics
  • A61P 37/02 - Immunomodulators
  • A61K 31/714 - Cobalamins, e.g. cyanocobalamin, vitamin B12
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/225 - Polycarboxylic acids

6.

AGENT FOR USE IN THE TREATMENT OF DYSLIPIDEMIA

      
Application Number EP2018055876
Publication Number 2018/162698
Status In Force
Filing Date 2018-03-09
Publication Date 2018-09-13
Owner FLEXOPHARM BRAIN GMBH & CO. KG (Germany)
Inventor Haghikia, Aiden

Abstract

The invention relates to an agent for use in the prophylaxis or treatment of dyslipidemia, in particular for the treatment of excessive LDL values, said agent containing propionic acid or a physiologically acceptable propionic acid derivative.

IPC Classes  ?

  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
  • A61P 3/06 - Antihyperlipidemics

7.

SUPPORTING IMMUNOMODULATORY AGENT

      
Application Number EP2016066350
Publication Number 2017/067681
Status In Force
Filing Date 2016-07-08
Publication Date 2017-04-27
Owner FLEXOPHARM BRAIN GMBH & CO. KG (Germany)
Inventor
  • Gold, Ralf
  • Haghikia, Aiden
  • Matthes, Ulrich

Abstract

The invention relates to a combination for use in the treatment of immune-mediated chronic inflammatory diseases and auto-immune diseases from C3,-8-carboxylic acids, to the physiologically acceptable salts and/or esters thereof as well as one or more fumaric acid esters and/or salts thereof, and to the use in the treatment of psoriasis and multiple sclerosis.

IPC Classes  ?

  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61P 37/02 - Immunomodulators
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
  • A61K 31/25 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol

8.

Propbalance

      
Application Number 1314390
Status Registered
Filing Date 2016-03-30
Registration Date 2016-03-30
Owner FLEXOPHARM BRAIN GmbH & Co. KG (Germany)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Chemical additives for food. Nutritional supplements; pharmaceuticals.

9.

Propicum

      
Application Number 1314391
Status Registered
Filing Date 2016-03-30
Registration Date 2016-03-30
Owner FLEXOPHARM BRAIN GmbH & Co. KG (Germany)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Chemical additives for food. Nutritional supplements; pharmaceuticals.

10.

SUPPORTING IMMUNOMODULATORY AGENT

      
Application Number EP2015074179
Publication Number 2016/059254
Status In Force
Filing Date 2015-10-19
Publication Date 2016-04-21
Owner FLEXOPHARM BRAIN GMBH & CO. KG (Germany)
Inventor
  • Gold, Ralf
  • Haghikia, Aiden
  • Linker, Ralf

Abstract

The invention relates to a supporting immunomodulatory agent for use in autoimmune diseases, containing C3-C8 carboxylic acids, the physiologically acceptable salts and/or esters with C1-C8 alkyl alcohols thereof, to the use of said carboxylic acids, salts and/or esters as supporting immunomodulators in autoimmune diseases and in chronic immune-mediated inflammatory diseases, and to food supplements having immunomodulatory effect and containing same.

IPC Classes  ?

11.

PROPICUM

      
Serial Number 79193982
Status Registered
Filing Date 2016-03-30
Registration Date 2017-09-12
Owner FLEXOPHARM BRAIN GmbH & Co. KG (Germany)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements, namely, propionic acid and propionic acid derivatives, in particular propionates; pharmaceuticals, namely, for the treatment of intestinal, metabolic, cardiovascular and autoimmunological disorders

12.

PROPIMMUN

      
Application Number 1279736
Status Registered
Filing Date 2015-11-02
Registration Date 2015-11-02
Owner FLEXOPHARM BRAIN GmbH & Co. KG (Germany)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements; medicine.