The present invention relates to a method for producing polydeoxyribonucleotide (PDRN) from a plant, PDRN produced by the method, and a cosmetic composition, a pharmaceutical composition, a quasi-drug composition, a food composition, a health functional food, and a feed composition, each comprising PDRN as an active ingredient for improving skin conditions. According to the present invention, high-purity and high-concentration PDRN can be produced from a plant, and the plant-derived PDRN produced thereby has skin protection against ultraviolet radiations, skin barrier enhancement, moisturization, wrinkle alleviation, skin regeneration, wound healing, or anti-aging effects, and thus can be advantageously used as a cosmetic composition for improving skin conditions, a pharmaceutical composition, a food composition, a health functional food, a quasi-drug composition, and a feed composition.
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
The present disclosure relates to a manufacturing method of a coffee cell and an adventitious root culture including increased bioactive substances and a food composition such as coffee using the same. The Coffea arabica plant cell or adventitious root produced by culturing the Coffea arabica plant cell or coffee adventitious root manufactured by the method of the present disclosure has an increased content of bioactive substances to increase skin regeneration, anti-aging and anti-wrinkle effects, and thus may be effectively used for related industries thereof.
The present disclosure relates to a recombinant vector for plant expression system in which expression is increased by a radio frequency. According to the present disclosure, since the recombinant vector for plant expression of the present disclosure significantly increased the expression of the target protein in plants by treatment of an eco-friendly and biologically stable radio frequency, there is an effect of overcoming a low protein expression problem of a method using plant cells while having an advantageous effect capable of replacing a conventional production method using animal cells or microorganisms.
The present invention relates to a high frequency-specific expression promoter. The promoter of the present invention increases the expression of a foreign gene under a high frequency condition as compared to under a non-high frequency condition. In addition, the promoter has an excellent effect of increasing the intracellular content of the aromatic amino acids tryptophan (Trp), phenylalanine (Phe) and tyrosine (Tyr) by means of the high frequency. Accordingly, the promoter has an effect of maximizing the production of a phenylpropanoid pathway-related gene and a phytochemical and thus may be usefully employed in relevant industries.
Nelumbo nucifera callus extract according to the present invention has an excellent whitening effect by containing a large amount of gallic acid, and thus can be advantageously used as a cosmetic composition.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
A61K 8/368 - Carboxylic acidsSalts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
The present invention relates to a composition comprising kisspeptin. Kisspeptin or an active fragment thereof according to an aspect of the present invention has activity to inhibit MMP-1 or inflammatory cytokines, and thus can be favorably used in the prevention, alleviation, or treatment of skin aging, skin damage, skin conditions, or inflammatory diseases.
A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
The present invention relates to Nelumbo nucifera callus having an increased content of gallic acid or an extract thereof and to a method for preparing the same. The Nelumbo nucifera callus extract according to the present invention has an excellent whitening effect by containing a large amount of gallic acid, and thus can be advantageously used as a cosmetic composition.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A61K 8/368 - Carboxylic acidsSalts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin
8.
Radiofrequency device for increasing intracellular bioactive substance and plant cell culture method using the same
There are provided a radiofrequency device for increasing amount of a bioactive substance in a plant cell and a plant cell culture method for increasing amount of useful intracellular secondary metabolites by using the radiofrequency device. The cell culture method of the present invention makes it possible to increase specific secondary metabolites such as daidzein, equol, and the like in a cell and thus can be used for development into various medicines, agricultural pesticides, spices, pigments, food additives, and cosmetics containing bioactive substances. Further, the cell culture method of the present invention improves conventional cell culture methods limitedly used for specific cells or specific metabolites for increasing amount of intracellular bioactive substances and thus can be widely applied to production of cells and secondary metabolites.
A01H 4/00 - Plant reproduction by tissue culture techniques
C12M 1/42 - Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
9.
LONG-LASTING DERIVATIVE THROUGH LAURIC ACID FUSION OF ANTIBACTERIAL PEPTIDE BETA-DEFENSIN 3 AND 3H, DEVELOPMENT OF SKIN PERMEABLE DERIVATIVE THROUGH CELL TRANSMISSIVE PEPTIDE FUSION, AND COSMETIC COMPOSITION CONTAINING SAME
The present invention relates to a long-lasting derivative through lauric acid fusion of antibacterial peptide beta-defensin 3 and 3H, a development of skin permeable derivative through cell transmissive peptide fusion, and a cosmetic composition containing the same and, more specifically, to antibacterial peptide lauroyl beta-defensin 3 and 3H, a novel cell transmissive peptide, and a cosmetic composition containing the same. The lauroyl-bound beta defensin 3 or 3H (homolog) peptide derivative according to the present invention has antibacterial activity and a performance of alleviating atopic dermatitis and acne, and thus is applicable as cosmetics, medical supplements, and medical materials for improving various skins including atopic dermatitis.
There are provided a radiofrequency device for increasing amount of a bioactive substance in a plant cell and a plant cell culture method for increasing amount of useful intracellular secondary metabolites by using the radiofrequency device. The cell culture method of the present invention makes it possible to increase specific secondary metabolites such as daidzein, equol, and the like in a cell and thus can be used for development into various medicines, agricultural pesticides, spices, pigments, food additives, and cosmetics containing bioactive substances. Further, the cell culture method of the present invention improves conventional cell culture methods limitedly used for specific cells or specific metabolites for increasing amount of intracellular bioactive substances and thus can be widely applied to production of cells and secondary metabolites.
The present invention relates to a caffeoyl alpha neoendorphin peptide derivative and to the use thereof as an anti-itch and anti-atopic material. More specifically, the present invention relates to a caffeoyl endorphin peptide derivative which can be used in a cosmetic material having an anti-inflammatory use in atopic dermatitis treatment and the like, and which is safe on the skin and at the same time resistant to breakdown due to peptidase or the like when coated onto the skin, and which is also outstandingly stable to temperature changes and the like, and to a use therefor.
The present invention relates to an external dermal agent and a functional food containing a rose placenta tissue-cultured product or an extract thereof, and more specifically, to an external dermal agent and a functional food containing a rose placenta tissue culture extract as an active ingredient. The external dermal agent and the functional food containing the rose placenta tissue-cultured product or the extract thereof, according to the present invention, activates skin cells by means of growth or proliferation of skin cells, thereby effectively regenerating the skin and smoothing wrinkles, and exhibits a superior antioxidant effect by containing a physiological activation substance.
A composition comprising a Sanguisorbae officinalis plant extract and at least one additional plant extract selected from the group consisting of an Ailanthus altissima plant extract, a Galla rhois gallnut plant extract, a Glycyrrhiza Glabra plant extract, a Rheum palmatum plant extract and a Scutellaria baicalensis plant extract is disclosed. Compositions comprising Ailanthus altissima plant extract or Ailanthone are also disclosed.
The present invention relates to a traditional Korean medicinal composition capable of improving atopic dermatitis by inhibiting TSLP, and more particularly, to a cosmetic composition and to a pharmaceutical composition containing Areca Catechu L. extract and Caryophylli cortex extract as active ingredients. The traditional Korean medicinal composition capable of improving atopic dermatitis according to the present invention competes with the activity of TSLP which is an immunopathologic mechanism of atopic dermatitis, to improve immune response of atopic dermatitis. The traditional Korean medicinal composition of the present invention uses natural extracts, and thus does not cause side effects even when applied to a human body over a long period of time.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
Disclosed are peptide derivatives, wherein glutathione-like peptides are connected to benzoic acid derivatives, and a cosmetic composition comprising the same. The peptide derivatives have excellent tyrosinase inhibition and anti-oxidative activities to show excellent skin whitening effect, biocompatibility without skin stimulation, and stability during long-term storage. Therefore, they can be effectively used for a cosmetic composition for skin whitening.
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