Goods & Services

Construction services; building services; construction of pharmaceutical facilities; onsite management relating to the construction of pharmaceutical manufacturing facilities; building and construction of factories; custom construction of factories and pharmaceutical manufacturing facilities; information, advice and consultancy in relation to all the aforesaid. Custom processing and manufacturing services; custom processing and manufacturing of pharmaceuticals; custom manufacture of pharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific and technological services; research and development; scientific, industrial and technical research, development and analysis services; scientific, industrial and technical research, development and analysis services in the field of biotechnology; industrial process development; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; software development, programming and implementation; design and development of software; design and development of manufacturing processes in the field of biopharmaceuticals; design of manufacturing methods; design of industrial buildings; design of manufacturing plants; engineering services; research laboratories; preparations of biological samples for analysis in research laboratories; designs services relating to process systems for the biotechnology industry; design services relating to plant for the biotechnology industry; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Cell cultures used in industry and science; mammalian cell cultures and vectors, being independent replicating pieces of DNA that can transfer DNA sequences, each for manufacture and development in the biotechnology industries; biological preparations for use in science; biological preparations for use in cell cultures; cell culture reagents for scientific and research use; media for cell culture for use in the biotechnological industry; chemical products for biotechnological purposes; chemicals for use in biotechnological manufacturing processes. Processing and manufacturing of vectors, cell cultures and recombinant proteins for use in biotechnology industries to the order and specification of others; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; custom processing and manufacturing services in the field of biopharmaceuticals; custom processing and manufacturing of biological products; custom manufacture of biopharmaceuticals; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific, industrial and technical research, development and analysis services; development and analysis services relating to the use of mammalian cell cultures and vectors in the field of biotechnology; biotechnology process development; development of processes for the use of mammalian cell cultures and vectors in the manufacture of biotechnology products; technical project studies; project studies relating to the use of mammalian cell cultures and vectors in the field of biotechnology; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; design and development of manufacturing processes in the field of biopharmaceuticals; development of chemicals for use in the manufacture of biotechnology products and pharmaceuticals; preparation of biological samples for analysis in research laboratories; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Construction services; building services; construction of pharmaceutical facilities; onsite management relating to the construction of pharmaceutical manufacturing facilities; building and construction of factories; custom construction of factories and pharmaceutical manufacturing facilities; information, advice and consultancy in relation to all the aforesaid. Custom processing and manufacturing services; custom processing and manufacturing of pharmaceuticals; custom manufacture of pharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific and technological services; research and development; scientific, industrial and technical research, development and analysis services; scientific, industrial and technical research, development and analysis services in the field of biotechnology; industrial process development; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; software development, programming and implementation; design and development of software; design and development of manufacturing processes in the field of biopharmaceuticals; design of manufacturing methods; design of industrial buildings; design of manufacturing plants; engineering services; research laboratories; preparation of biological samples for analysis in research laboratories; designs services relating to process systems for the biotechnology industry; design services relating to plant for the biotechnology industry; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Chemicals used in industry and science; cell cultures used in industry and science; biological preparations for use in science; biological preparations for use in cell cultures; proteins for use in industry, enzymes; microbial preparations being chemicals for industry; cultures of micro-organisms other than for medical or veterinary use; chemical reagents; organic chemicals for use in science, namely genes being DNA sequences; plasmids being small independently replicating pieces of DNA and vectors being small independently replicating pieces of DNA that can transfer DNA sequences, being chemicals for use in science; cell culture reagents for scientific and research use; media for cell culture for use in the biotechnological industry; chemical products for biotechnological purposes; chemicals for use in biotechnological manufacturing processes. Processing and manufacturing of chemicals and proteins; custom manufacture of chemicals and proteins for use in biotechnology and pharmaceuticals; manufacture, processing and production of scientific and industrial products to the order and specification of others; custom processing and manufacturing services; custom processing and manufacturing of biological products; custom manufacture of biopharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific, industrial and technical research; scientific analysis; technological analysis services; scientific research and development; industrial process development; industrial design services; provision of facilities for scientific, industrial and technical research and development; research and development of scientific, industrial and technical products; technical project studies; testing of scientific, industrial and technical products; scientific, industrial and technical research, development and analysis services in the field of biotechnology; development of processes for the use in the manufacture of biotechnology products; project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; design and development of manufacturing processes in the field of biopharmaceuticals; development of chemicals for use in the manufacture of biotechnology products and pharmaceuticals; preparation of biological samples for analysis in research laboratories; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Cell cultures used in industry and science; mammalian cell cultures and vectors, being independent replicating pieces of DNA that can transfer DNA sequences, each for manufacture and development in the biotechnology industries; biological preparations for use in science; biological preparations for use in cell cultures; cell culture reagents for scientific and research use; media for cell culture for use in the biotechnological industry; chemical products for biotechnological purposes; chemicals for use in biotechnological manufacturing processes. Processing and manufacturing of vectors, cell cultures and recombinant proteins for use in biotechnology industries to the order and specification of others; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; custom processing and manufacturing services; custom processing and manufacturing of biological products; custom manufacture of biopharmaceuticals; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific, industrial and technical research, development and analysis services; development and analysis services relating to the use of mammalian cell cultures and vectors in the field of biotechnology; industrial process development; development of processes for the use of mammalian cell cultures and vectors in the manufacture of biotechnology products; technical project studies; project studies relating to the use of mammalian cell cultures and vectors in the field of biotechnology; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; design and development of manufacturing processes in the field of biopharmaceuticals; development of chemicals for use in the manufacture of biotechnology products and pharmaceuticals; preparation of biological samples for analysis in research laboratories; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Construction services; building services; construction of pharmaceutical facilities; onsite management relating to the construction of pharmaceutical manufacturing facilities; building and construction of factories; custom construction of factories and pharmaceutical manufacturing facilities; information, advice and consultancy in relation to all the aforesaid. Custom processing and manufacturing services; custom processing and manufacturing of pharmaceuticals; custom manufacture of pharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific and technological services; research and development; scientific, industrial and technical research, development and analysis services; scientific, industrial and technical research, development and analysis services in the field of biotechnology; industrial process development; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; software development, programming and implementation; design and development of software; design and development of manufacturing processes in the field of biopharmaceuticals; design of manufacturing methods; design of industrial buildings; design of manufacturing plants; engineering services; research laboratories; preparation of biological samples for analysis in research laboratories; designs services relating to process systems for the biotechnology industry; design services relating to plant for the biotechnology industry; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Cell cultures used in industry and science; mammalian cell cultures and vectors, being independent replicating pieces of DNA that can transfer DNA sequences, each for manufacture and development in the biotechnology industries; biological preparations for use in science; biological preparations for use in cell cultures; cell culture reagents for scientific and research use; media for cell culture for use in the biotechnological industry; chemical products for biotechnological purposes; chemicals for use in biotechnological manufacturing processes. Processing and manufacturing of vectors, cell cultures and recombinant proteins for use in biotechnology industries to the order and specification of others; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; custom processing and manufacturing services; custom processing and manufacturing of biological products; custom manufacture of biopharmaceuticals; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific, industrial and technical research, development and analysis services; development and analysis services relating to the use of mammalian cell cultures and vectors in the field of biotechnology; industrial process development; development of processes for the use of mammalian cell cultures and vectors in the manufacture of biotechnology products; technical project studies; project studies relating to the use of mammalian cell cultures and vectors in the field of biotechnology; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; design and development of manufacturing processes in the field of biopharmaceuticals; development of chemicals for use in the manufacture of biotechnology products and pharmaceuticals; preparation of biological samples for analysis in research laboratories; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Chemicals used in industry and science; cell cultures used in industry and science; biological preparations for use in science; biological preparations for use in cell cultures; proteins for use in industry, enzymes; microbial preparations being chemicals for industry; cultures of micro-organisms other than for medical or veterinary use; chemical reagents; organic chemicals for use in science, namely genes being DNA sequences; plasmids being small independently replicating pieces of DNA and vectors being small independently replicating pieces of DNA that can transfer DNA sequences, being chemicals for use in science; cell culture reagents for scientific and research use; media for cell culture for use in the biotechnological industry; chemical products for biotechnological purposes; chemicals for use in biotechnological manufacturing processes. Processing and manufacturing of chemicals and proteins; custom manufacture of chemicals and proteins for use in biotechnology and pharmaceuticals; manufacture, processing and production of scientific and industrial products to the order and specification of others; custom processing and manufacturing services; custom processing and manufacturing of biological products; custom manufacture of biopharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific, industrial and technical research; scientific analysis; technological analysis services; scientific research and development; industrial process development; industrial design services; provision of facilities for scientific, industrial and technical research and development; research and development of scientific, industrial and technical products; technical project studies; testing of scientific, industrial and technical products; scientific, industrial and technical research, development and analysis services in the field of biotechnology; development of processes for the use in the manufacture of biotechnology products; project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; design and development of manufacturing processes in the field of biopharmaceuticals; development of chemicals for use in the manufacture of biotechnology products and pharmaceuticals; preparation of biological samples for analysis in research laboratories; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Custom processing and manufacturing services; custom processing and manufacturing of pharmaceuticals; custom manufacture of pharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Construction services; building services; construction of pharmaceutical facilities; onsite management relating to the construction of pharmaceutical manufacturing facilities; building and construction of factories; custom construction of factories and pharmaceutical manufacturing facilities; information, advice and consultancy in relation to all the aforesaid. Scientific and technological services; research and development; scientific, industrial and technical research, development and analysis services; scientific, industrial and technical research, development and analysis services in the field of biotechnology; industrial process development; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; software development, programming and implementation; design and development of software; design and development of manufacturing processes in the field of biopharmaceuticals; design of manufacturing methods; design of industrial buildings; design of manufacturing plants; engineering services; research laboratories; preparation of biological samples for analysis in research laboratories; designs services relating to process systems for the biotechnology industry; design services relating to plant for the biotechnology industry; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Cell cultures used in industry and science; mammalian cell cultures and vectors, being independent replicating pieces of DNA that can transfer DNA sequences, each for manufacture and development in the biotechnology industries; biological preparations for use in science; biological preparations for use in cell cultures; cell culture reagents for scientific and research use; media for cell culture for use in the biotechnological industry; chemical products for biotechnological purposes; chemicals for use in biotechnological manufacturing processes. Processing and manufacturing of vectors, cell cultures and recombinant proteins for use in biotechnology industries to the order and specification of others; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; custom processing and manufacturing services in the field of biopharmaceuticals; custom processing and manufacturing of biological products; custom manufacture of biopharmaceuticals; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Scientific, industrial and technical research, development and analysis services; development and analysis services relating to the use of mammalian cell cultures and vectors in the field of biotechnology; biotechnology process development; development of processes for the use of mammalian cell cultures and vectors in the manufacture of biotechnology products; technical project studies; project studies relating to the use of mammalian cell cultures and vectors in the field of biotechnology; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; design and development of manufacturing processes in the field of biopharmaceuticals; development of chemicals for use in the manufacture of biotechnology products and pharmaceuticals; preparation of biological samples for analysis in research laboratories; information, advice and consultancy in relation to all the aforesaid.

Goods & Services

Custom processing and manufacturing services; custom processing and manufacturing of pharmaceuticals; custom manufacture of pharmaceuticals; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others; cell culture manufacturing services for others; custom manufacture of biologics; information, advice and consultancy in relation to all the aforesaid. Construction services; building services; construction of pharmaceutical facilities; onsite management relating to the construction of pharmaceutical manufacturing facilities; building and construction of factories; custom construction of factories and pharmaceutical manufacturing facilities; information, advice and consultancy in relation to all the aforesaid. Scientific and technological services; research and development; scientific, industrial and technical research, development and analysis services; scientific, industrial and technical research, development and analysis services in the field of biotechnology; industrial process development; development of processes for the use in the manufacture of biotechnology products; technical project studies; biotechnology testing; research and consultancy in the field of biotechnology; research and development in the pharmaceutical and biotechnology industry; scientific, technological and pharmaceutical process development and design; biopharmaceutical product development; software development, programming and implementation; design and development of software; design and development of manufacturing processes in the field of biopharmaceuticals; design of manufacturing methods; design of industrial buildings; design of manufacturing plants; engineering services; research laboratories; preparation of biological samples for analysis in research laboratories; designs services relating to process systems for the biotechnology industry; design services relating to plant for the biotechnology industry; information, advice and consultancy in relation to all the aforesaid.

Abstract

The present invention relates to an inkjet ink comprising: a continuous aqueous phase; a dispersed encapsulated pigment consisting of pigment particles encapsulated by a cross-linked polymer coating having pendant hydrophilic groups including hydroxyl groups; and a cross-linking agent having two or more protected reactive groups, wherein the two or more protected reactive groups, when deprotected, are reactive to hydroxyl groups. The present invention also relates to a method of inkjet printing, a dispersion and a printed substrate.

IPC Classes  ?

• C09D 11/322 - Pigment inks
• C09D 11/326 - Pigment inks characterised by the pigment dispersant
• C09D 11/107 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds from unsaturated acids or derivatives thereof
• D06P 5/30 - Ink jet printing

Abstract

The present invention relates to an inkjet ink comprising: a continuous aqueous phase; a dispersed encapsulated pigment comprising pigment particles encapsulated by a cross-linked polymer coating having pendant hydrophilic groups including hydroxyl groups; and a cross-linking agent having two or more protected reactive groups, wherein the two or more protected reactive groups, when deprotected, are reactive to hydroxyl groups. The present invention also relates to a method of inkjet printing, a dispersion and a printed substrate.

IPC Classes  ?

• C09D 11/322 - Pigment inks
• C09D 11/326 - Pigment inks characterised by the pigment dispersant
• C09D 11/107 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds from unsaturated acids or derivatives thereof
• D06P 5/30 - Ink jet printing

Abstract

Described is a method and component parts of a recombinant expression system for the expression of a biological molecule. In particular, an isolated vesicle nucleating polypeptide (VNp) comprising an amphipathic alpha helix polypeptide derived from the amino terminus of synuclein isoforms and variants thereof is used to promote, enhance or increase the formation of vesicles in the expression system to enable purification of the biological molecule.

IPC Classes  ?

• C07K 14/47 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans from vertebrates from mammals
• A61K 9/50 - Microcapsules
• C12N 9/50 - Proteinases
• C12N 15/67 - General methods for enhancing the expression
• C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Abstract

Described is a method and component parts of a recombinant expression system for the expression of a biological molecule. In particular, an isolated vesicle nucleating polypeptide (VNp) comprising an amphipathic alpha helix polypeptide derived from the amino terminus of synuclein isoforms and variants thereof is used to promote, enhance or increase the formation of vesicles in the expression system to enable purification of the biological molecule.

IPC Classes  ?

• C07K 14/47 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans from vertebrates from mammals

Abstract

A process for purifying a composition comprising water, a target substance, impurities and optionally cells, the process comprising the steps (A) and (B): (A) preparing a liquid feedstock by performing step (Ai) and/or (Aii) on the composition: (Ai) removing at least some of the cells from the composition; (Aii) concentrating the composition by removing water therefrom; and (B) passing the liquid feedstock through an apparatus comprising at least two processing units, each such unit producing a product stream containing purified target substance and optionally a waste stream comprising at least some of the impurities, wherein each unit comprises specified components (i) to (v). The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 15/38 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups , e.g. affinity, ligand exchange or chiral chromatography
• B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters

Abstract

Apparatus for purifying a liquid comprising a target substance comprising at least two units arranged in series such that the feed stream of the second and any subsequent units comprises the product stream from a downstream unit, wherein each unit comprises specified components (i) to (vi), including a a switchable bypass assembly. Also claimed are the units and a flowpath assembly. The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
• C07K 1/16 - Extraction; Separation; Purification by chromatography

Abstract

A process for purifying a liquid feedstock comprising a monoclonal antibody and impurities, the process comprising passing the liquid feedstock through an apparatus comprising at least two processing units, each such unit producing a product stream containing purified monoclonal antibody and optionally a waste stream comprising at least some of the impurities, wherein each unit comprises specified components (i) to (v) which include a multiple inlet flow-controller comprising two or more variable flow inlet valves for in situ production of a bioprocessing liquid by combining at least two liquids in a desired ratio. One of the units performs chromatography and another performs viral inactivation. The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• C07K 1/36 - Extraction; Separation; Purification by a combination of two or more processes of different types
• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
• C07K 1/22 - Affinity chromatography or related techniques based upon selective absorption processes
• C07K 1/18 - Ion-exchange chromatography
• C07K 16/06 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies from serum
• B01D 15/14 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 15/38 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups , e.g. affinity, ligand exchange or chiral chromatography
• B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion

Abstract

A process for the production of a target polypeptide is provided. The process comprises expression of an expression vector for expressing a target polypeptide in a host cell, preferably a mammalian cell, the expression vector comprising an expression cassette comprising a polynucleotide encoding a recombinant polypeptide operably linked to a fibronectin secretion leader sequence; and recovering the target polypeptide.

IPC Classes  ?

• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C07K 16/06 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies from serum
• C07K 16/30 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Goods & Services

Medical apparatus for use in endoscopy; Endoscopy cameras for medical purposes; Optical instruments for medical endoscopy; Medical diagnostic apparatus for medical purposes; Medical analytical apparatus for medical purposes; Medical instruments; Medical imaging apparatus; Medical apparatus and devices; Electronic apparatus for medical purposes; Medical diagnostic instruments; Medical analysis instruments; Apparatus for use in medical analysis; Diagnostic instruments for medical use. Demonstration of goods; Presentation of goods and services; Demonstration of goods for promotional purposes; Demonstration of goods for advertising purposes; Presentation of goods on communications media, for retail purposes; Display services for merchandise; Arranging business introductions relating to the buying and selling of products; Demonstration of products; Advertising particularly services for the promotion of goods; Retail services in relation to medical apparatus; Wholesale services in relation to medical apparatus; Promoting and conducting trade shows; Organisation and conducting of product presentations; Planning and conducting of trade fairs, exhibitions and presentations for economic or advertising purposes.

Goods & Services

Continuous production, including continuous manufacture and purification, of biological products such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells, to the order and specification of others; continuous expression, isolation and purification, of biological products such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells, to the order and specification of others; continuous connected upstream and downstream production of biological products such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells, to the order and specification of others. Scientific, industrial and technical research, development and analysis services related to continuous production, including continuous manufacture and purification, of biological products such as such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells; process development related to the continuous production, including continuous manufacture and purification, of biological products such as such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells; industrial design services related to the continuous production, including continuous manufacture and purification, of biological products such as such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells; provision of facilities for scientific, industrial and technical research development related to the continuous production, including continuous manufacture and purification, of biological products such as such as cells, viruses and biomolecules, including genes and proteins, obtained from recombinant cells.

Abstract

A static mixing apparatus for mixing a fluid, preferably a liquid is provided. The mixer comprises a plurality of chambers (5, 8, 12, 15) in series, the first chamber (5) of the series comprising a fluid inlet (4), and the final chamber (15) of the series comprising a fluid outlet (16), each chamber other than the final chamber in the series being in fluid connection with a subsequent chamber, the fluid connection comprising a plurality of orifices (7, 10, 11, 14) dispersed along a direction of flow, the nearest point to the fluid inlet of each subsequent orifice to the inlet overlapping with the furthest point from the fluid inlet of the previous orifice, and being off-set along the direction of flow from the previous orifice.

IPC Classes  ?

• B01F 5/06 - Mixers in which the components are pressed together through slits, orifices, or screens

Goods & Services

Colouring matters; colorants; pigments; printing inks; pigment dispersions; printing inks containing pigment dispersions.

Goods & Services

Inks for printing; inkjet inks; ink or toner cartridges, filled, for inkjet printers.

Abstract

A method of concentration of a liquid comprising a biomolecule is provided. The method comprises passing the liquid through a tangential flow filtration device under pressure, wherein the pressure applied is varied between at least a higher pressure and a lower pressure. Preferably, the variation in pressure is delivered by the use of a variable flow-controller, such as a valve.

IPC Classes  ?

• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Abstract

A composite ion exchange membrane comprising components (a) and (b): (a) a membrane layer comprising ionic groups, two opposing surfaces and optionally a porous support; (b) a layer comprising sulpho groupsbound to at least one of the at least two opposing surfacesof the membrane layer (a); wherein the layer comprising sulpho groupshas a thickness of less than 100nm and the composite ion exchange membranehasa surface zeta potential of 0 to -7.5mV.

IPC Classes  ?

• C08J 5/22 - Films, membranes or diaphragms
• B01D 61/42 - Electrodialysis; Electro-osmosis
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranes; Membrane supports
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• B01D 71/40 - Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
• B01D 71/82 - Macromolecular material not specifically provided for in a single one of groups characterised by the presence of specified groups, e.g. introduced by chemical after-treatment

Abstract

Apparatus for purifying a liquid comprising a target substance comprising at least two units arranged in series such that the feed stream of the second and any subsequent units comprises the product stream from a downstream unit, wherein each unit comprises specified components (i) to (vi), including a a switchable bypass assembly. Also claimed are the units and a flowpath assembly. The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• C07K 1/14 - Extraction; Separation; Purification
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
• C12M 1/00 - Apparatus for enzymology or microbiology

Abstract

in situin situ production of a bioprocessing liquid by combining at least two liquids in a desired ratio. One of the units performs chromatography and another performs viral inactivation. The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
• B01D 15/38 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups , e.g. affinity, ligand exchange or chiral chromatography
• C07K 1/16 - Extraction; Separation; Purification by chromatography
• C07K 1/36 - Extraction; Separation; Purification by a combination of two or more processes of different types
• C12N 7/04 - Inactivation or attenuation; Producing viral sub-units
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

Abstract

A process for purifying a composition comprising water, a target substance, impurities and optionally cells, the process comprising the steps (A) and (B): (A) preparing a liquid feedstock by performing step (Ai) and/or (Aii) on the composition: (Ai) removing at least some of the cells from the composition; (Aii) concentrating the composition by removing water therefrom; and (B) passing the liquid feedstock through an apparatus comprising at least two processing units, each such unit producing a product stream containing purified target substance and optionally a waste stream comprising at least some of the impurities, wherein each unit comprises specified components (i) to (v). The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• C07K 1/36 - Extraction; Separation; Purification by a combination of two or more processes of different types
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• G01N 30/46 - Flow patterns using more than one column
• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier

Abstract

Apparatus for purifying a liquid comprising a target substance comprising at least two units arranged in series such that the feed stream of the second and any subsequent units comprises the product stream from a downstream unit, wherein each unit comprises specified components (i) to (vi), including a a switchable bypass assembly. Also claimed are the units and a flowpath assembly. The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

IPC Classes  ?

• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• G01N 30/46 - Flow patterns using more than one column
• C07K 1/36 - Extraction; Separation; Purification by a combination of two or more processes of different types
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• C12M 1/00 - Apparatus for enzymology or microbiology
• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier

Abstract

Apparatus for processing a liquid comprising a target substance, preferably a biomolecule, is provided. The apparatus comprises at least a first and a second means for carrying out a unit operation, each means for carrying out a unit operation comprising a feed for a liquid in fluid connection with the inlet of a flow-controller comprising a variable flow inlet valve and an outlet, wherein at least one of the means for carrying out a unit operation comprises feeds for at least two liquids, the feeds being in fluid connection with the inlets of a multiple inlet flow-controller comprising two or more variable flow inlet valves for dosing the at least two liquids, the flow-controller also comprising an outlet; a feed for a liquid feedstock comprising the target substance in fluid connection with the outlet from the flow-controller thereby to enable combination of the feed for a liquid comprising the target substance with the mixed bioprocessing liquids to produce a device feed; a device for achieving a processing operation comprising a device inlet and a device outlet, the device inlet being in fluid connection with the device feed; and a means for imparting flow through the flow controller and from the feed for the liquid feedstock through the processing device via the device inlet; and wherein the feed for a liquid feedstock comprising the target substance for the second means for carrying out a unit operation comprises the outlet from the first means for carrying out a unit operation.

IPC Classes  ?

• G01N 30/46 - Flow patterns using more than one column
• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Goods & Services

Apparatus for use in separation and purification, including separation and purification of biological products such as cells, viruses and biomolecules, including genes and proteins; liquid chromatography apparatus for laboratory or scientific use; ion exchange apparatus for laboratory or scientific use; ultrafiltration apparatus for laboratory or scientific use; diafiltration apparatus for laboratory or scientific use; apparatus for diluting or concentrating biological products for laboratory or scientific use; apparatus for removal of viruses from solutions, including biological products, for laboratory or scientific use; apparatus for inactivation of viruses from solutions for laboratory or scientific use; apparatus for membrane filtration for laboratory or scientific use; apparatus for performing chromatographic separations and parts thereof for laboratory or scientific use; flowpaths, parts and fittings, including tubing, valves, in-line mixers, pressure sensors, temperature sensors and/or other sensors for all the aforesaid goods; computer software for control of the aforesaid goods; computer software for management of biological product purification processes. Apparatus for use in separation and purification for industrial purposes, including separation and purification of biological products such as cells, viruses and biomolecules, including genes and proteins; liquid chromatography apparatus for industrial purposes; ion exchange apparatus for industrial purposes; ultrafiltration apparatus for industrial purposes; diafiltration apparatus for industrial purposes; apparatus for diluting or concentrating biological products for industrial purposes; apparatus for removal of viruses from solutions, including biological products for industrial purposes; apparatus for inactivation of viruses from solutions for industrial purposes; apparatus for membrane filtration for industrial purposes; apparatus for performing chromatographic separations and parts thereof for industrial purposes; flowpaths, parts and fittings, including tubing, valves, in-line mixers, pressure sensors, temperature sensors and/or other sensors for all the aforesaid goods. Processing and manufacturing of biological products such as cells, viruses and biomolecules, including genes and proteins, including to the order and specification of others; manufacture, processing and production of biomolecules such as cells, viruses and biomolecules, including genes and proteins, to the order and specification of others. Scientific, industrial and technical research, development and analysis services related to biological products such as such as cells, viruses and biomolecules, including genes and proteins; process development related to the manufacture and purification of biological products such as such as cells, viruses and biomolecules, including genes and proteins; industrial design services related to the manufacture and purification of biological products such as such as cells, viruses and biomolecules, including genes and proteins; provision of facilities for scientific, industrial and technical research development related to the manufacture and purification of biological products such as such as cells, viruses and biomolecules, including genes and proteins.

Abstract

A protein expression system for use in a prokaryotic host is provided, the expression system comprising: a) an expression cassette comprising a nucleic acid sequence encoding a protein of interest operably linked to a T7 RNA polymerase-dependent promoter; and b) an expression cassette comprising a nucleic acid sequence encoding T7 RNA polymerase operably linked to a host polymerase-dependent λ phage promoter and a single perfect palindrome operator sequence; wherein the expression cassette for T7 RNA polymerase is located on the chromosome of a host cell.

IPC Classes  ?

• C12N 15/73 - Expression systems using phage lambda regulatory sequences
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/72 - Expression systems using regulatory sequences derived from the lac-operon

Goods & Services

Continuous, custom production or manufacture, namely continuous extraction, and purification, of biological products in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells, to the order and specification of others; Continuous, custom manufacture, namely continuous expression isolation, and purification, of biological products in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells, to the order and specification of others; Continuous, custom production or manufacture, namely, continuous connected upstream and downstream manufacture of biological products in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells, to the order and specification of others Scientific, industrial and technical research, development and analysis services related to continuous production, continuous manufacture and purification, of biological products in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells; Scientific research and development, namely process development related to the continuous production, continuous manufacture and purification, of biological products in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells; Industrial design services related to the continuous production, continuous manufacture and purification, of biological in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells; Provision of facilities for scientific, industrial and technical research development related to the continuous production, continuous manufacture and purification, of biological products in the nature of cells, viruses and biomolecules, genes and proteins, obtained from recombinant cells

Abstract

A membrane comprising polymer particles fused together and pores between the fused particles, wherein: (a) the polymer particles have an average diameter of 0.1 to 5,000nm; (b) the membrane having a mean flow pore size of 5nm to 5,000nm; and (c) the membrane has been obtained by a process comprising curing a composition comprising: (i) a monomer; (ii) an organic polymerisation retardant; and (iii) an inert solvent; 0.149. The membranes are useful for detecting metal ions and for filtering and/or purifying biomoleculesand compositions comprising metal-ions.

IPC Classes  ?

• B01D 71/40 - Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters

Abstract

Apparatus for in-line liquid exchanging a biomolecule-containing liquid is provided. The apparatus comprises a means for mixing at least two liquids comprising a multiple inlet flow-controller, the means for mixing also comprising an outlet in fluid connection with a tangential flow filtration device configured in single-pass mode.

IPC Classes  ?

• B01D 61/18 - Apparatus therefor
• B01D 61/20 - Accessories; Auxiliary operations
• C07K 1/14 - Extraction; Separation; Purification
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 61/16 - Feed pretreatment
• B01D 61/22 - Controlling or regulating

Abstract

A method for preparing an aqueous solution of a defined pH comprising an acid, a base and optionally one or more additives is provided. The method comprises the steps of: a) calculating the theoretical concentrations of acid and base for the solution to have the defined pH using the Henderson-Hasselbach equation in combination with the Debye Huckel theory for a range of different additive concentrations; b) preparing a sample of the buffer for the range of additive concentrations and measuring the actual pH for each additive concentration; c) calculating a value for delta pH, ΔpH, being the difference between the theoretical pH and the actual pH, for each additive concentration; d) generating a mathematical model describing the relationship of ΔpH with additive concentration; e) selecting the defined pH and additive concentrations; f) using the mathematical model generated in step d) to calculate ΔpH for the defined pH and additive concentration; g) calculating a ΔpH-corrected pH by summing the defined pH and delta pH; h) using the ΔpH-corrected pH to calculate the concentrations of acid and base using the Henderson-Hasselbach equation in combination with the Debye Huckel theory; i) preparing the solution using the concentrations calculated in step h).

IPC Classes  ?

• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• G05D 21/02 - Control of chemical or physico-chemical variables, e.g. pH-value characterised by the use of electric means
• B01F 25/42 - Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
• B01F 35/221 - Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
• B01F 35/71 - Feed mechanisms

Goods & Services

Fluid processing system for use in the separation and purification of biological products such as cells, viruses and biomolecules, including nucleic acids and proteins, for bioprocessing and pharmaceutical research, comprised primarily of chromatography apparatus for laboratory use, laboratory filters, and fluid handling devices used for bioprocessing applications and component parts and fittings; Liquid chromatography apparatus for laboratory use; Ion exchange chromatography apparatus for the treatment of fluids for laboratory use; Ultrafiltration apparatus for laboratory or scientific research use, namely, ultrafiltration laboratory filters and laboratory ultrafiltration filter membranes as part of scientific apparatus; Diafiltration apparatus for laboratory or scientific research use, namely, laboratory diafiltration filters; Scientific, laboratory, and measuring apparatus and instruments for diluting or concentrating biological products for laboratory or scientific research use, namely, tangential flow filtration devices for preparation of biological samples for use in the biopharmaceutical industry; Laboratory filters in the nature of viral filtration apparatus for removal of viruses from solutions for laboratory or scientific research use; Membrane filtration apparatus in the nature of membrane laboratory filters for use in laboratory equipment in the biopharmaceutical industry for treating biological fluids and solutions; Chromatography apparatus and component parts thereof for laboratory or scientific research use; Parts and fittings, namely, tubing, valves, in-line mixers, pressure sensors, temperature sensors and electronic sensors specially adapted for use with all of the aforementioned goods; Computer software for control of the aforesaid goods, namely, downloadable and recorded software for operating a fluid processing apparatus for laboratory or scientific research use comprising chromatography, membrane filtration, tangential flow filtration, viral filtration, ultrafiltration, diafiltration, viral filtration, viral inactivation, in-line conditioning, and buffer management components and systems; Computer software for management of biological product purification processes, namely, downloadable and recorded software for managing the purification of cells, viruses, and biomolecules in the nature of nucleic acids and proteins Fluid processing system apparatus and system for use in the separation and purification of biological products such as cells, viruses and biomolecules, including nucleic acids and proteins, for the pharmaceutical and biomanufacturing industries, namely, chromatography apparatus for industrial use and apparatus and instruments for use in the purification, conditioning, separation and sterilization of liquids and gases used in the biotechnology, pharmaceutical, medical, and biopharmaceutical industries; Liquid chromatography apparatus for industrial purposes; Ion exchange apparatus for the treatment of fluids for industrial purposes; Ultrafiltration apparatus for industrial purposes, namely, apparatus and instruments for use in the purification, separation and sterilization of liquids and gases used in the biotechnology, pharmaceutical, medical, and biopharmaceutical industries; Diafiltration apparatus, namely, aqueous solution filtering systems and components and biological fluid filtering systems and components for industrial purposes being apparatus and instruments for use in the purification, separation and sterilization of liquids used in the biotechnology, pharmaceutical, medical, and biopharmaceutical industries; Apparatus for diluting or concentrating biological products for industrial purposes, namely, tangential flow filtration apparatus being apparatus for use in the purification, separation and sterilization of liquids and gases used in the biotechnology, pharmaceutical, medical, and biopharmaceutical industries; Viral filtration apparatus for removal of viruses from solutions for industrial purposes, namely, apparatus and instruments for use in the purification, separation and sterilization of liquids and gases used in the biotechnology, pharmaceutical, medical, and biopharmaceutical industries; Virus inactivation and disinfection apparatus for the treatment of biological products in the field of biomanufacturing and pharmaceuticals, all for industrial purposes in the nature of apparatus and instruments for use in the purification, separation and sterilization of liquids and gases used in the biotechnology, pharmaceutical, medical, and biopharmaceutical industries; Membrane filtration apparatus for industrial purposes in the nature of membrane filter cartridges for the separation of biomolecules in biopharmaceutical production; Chromatography apparatus for industrial purposes and component parts thereof; Parts and fittings, namely, tubing, valves, in-line mixers, pressure sensors, temperature sensors and electric sensors, specially adapted for use with the aforementioned Processing and manufacturing of biological products such as cells, viruses and biomolecules, including genes and proteins, namely, manufacturing of pharmaceuticals using biological organisms in the manufacturing process to the order and specification of others; Manufacture of biomolecules such as cells, viruses and biomolecules, including genes and proteins, to the order and specification of others Scientific research, industrial biomedical research and technical product research and development services in the field of biomanufacturing, bioprocessing and pharmaceuticals related to biological products such as cells, viruses and biomolecules, including nucleic acids and proteins; Process development services related to the manufacture and purification of biological products such as such as cells, viruses and biomolecules, including nucleic acids and proteins, namely, biomedical and pharmaceutical research; Industrial design services related to the manufacture and purification of biological products such as cells, viruses and biomolecules, including nucleic acids and proteins; Provision of facilities for scientific, industrial and technical research and development in the field of biomanufacturing, bioprocessing and pharmaceuticals, namely, scientific laboratory services

Abstract

A static mixing apparatus for mixing a fluid, preferably a liquid is provided. The mixer comprises a plurality of chambers (5, 8, 12, 15) in series, the first chamber (5) of the series comprising a fluid inlet (4), and the final chamber (15) of the series comprising a fluid outlet (16), each chamber other than the final chamber in the series being in fluid connection with a subsequent chamber, the fluid connection comprising a plurality of orifices (7, 10, 11, 14) dispersed along a direction of flow, the nearest point to the fluid inlet of each subsequent orifice to the inlet overlapping with the furthest point from the fluid inlet of the previous orifice, and being off-set along the direction of flow from the previous orifice.

IPC Classes  ?

• B01F 5/06 - Mixers in which the components are pressed together through slits, orifices, or screens

Abstract

Membranes having an average pore size of 5 nm to 5,000 nm and a porosity of 15% or more, said membrane being obtainable by a process comprising curing a composition comprising: to 64 wt% of (i) a cross-linking agent comprising at least one cationic group; and 36 to 95wt% of (ii) inert solvent(s). The membranes are useful for detecting, filtering and/or purifying biomolecules.

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 15/34 - Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• C08J 5/22 - Films, membranes or diaphragms

Abstract

Membranes having an average pore size of 5 nm to 5,000 nm and a porosity of 10% or more, said membrane being obtainable by a process comprising curing a composition comprising: (i) a cross-linking agent comprising at least one anionic group; and (ii) inert solvent(s). The membranes are useful for detecting metal ions and for filtering and/or purifying biomolecules and compositions comprising metal-ions.

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 15/34 - Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
• B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• C08J 5/22 - Films, membranes or diaphragms

Abstract

Apparatus for processing a liquid comprising a target substance, preferably a biomolecule, is provided. The apparatus comprises at least a first and a second means for carrying out a unit operation, each means for carrying out a unit operation comprising a feed for a liquid in fluid connection with the inlet of a flow-controller comprising a variable flow inlet valve and an outlet, wherein at least one of the means for carrying out a unit operation comprises feeds for at least two liquids, the feeds being in fluid connection with the inlets of a multiple inlet flow-controller comprising two or more variable flow inlet valves for dosing the at least two liquids, the flow-controller also comprising an outlet; a feed for a liquid feedstock comprising the target substance in fluid connection with the outlet from the flow-controller thereby to enable combination of the feed for a liquid comprising the target substance with the mixed bioprocessing liquids to produce a device feed; a device for achieving a processing operation comprising a device inlet and a device outlet, the device inlet being in fluid connection with the device feed; and a means for imparting flow through the flow controller and from the feed for the liquid feedstock through the processing device via the device inlet; and wherein the feed for a liquid feedstock comprising the target substance for the second means for carrying out a unit operation comprises the outlet from the first means for carrying out a unit operation.

IPC Classes  ?

• C07K 1/16 - Extraction; Separation; Purification by chromatography
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• G01N 30/46 - Flow patterns using more than one column
• B01D 61/14 - Ultrafiltration; Microfiltration
• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Abstract

Apparatus for processing a liquid comprising a target substance, preferably a biomolecule, is provided. The apparatus comprises at least a first and a second means for carrying out a unit operation, each means for carrying out a unit operation comprising a feed for a liquid in fluid connection with the inlet of a flow-controller comprising a variable flow inlet valve and an outlet, wherein at least one of the means for carrying out a unit operation comprises feeds for at least two liquids, the feeds being in fluid connection with the inlets of a multiple inlet flow-controller comprising two or more variable flow inlet valves for dosing the at least two liquids, the flow-controller also comprising an outlet; a feed for a liquid feedstock comprising the target substance in fluid connection with the outlet from the flow-controller thereby to enable combination of the feed for a liquid comprising the target substance with the mixed bioprocessing liquids to produce a device feed; a device for achieving a processing operation comprising a device inlet and a device outlet, the device inlet being in fluid connection with the device feed; and a means for imparting flow through the flow controller and from the feed for the liquid feedstock through the processing device via the device inlet; and wherein the feed for a liquid feedstock comprising the target substance for the second means for carrying out a unit operation comprises the outlet from the first means for carrying out a unit operation.

IPC Classes  ?

• C07K 1/16 - Extraction; Separation; Purification by chromatography
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• G01N 30/46 - Flow patterns using more than one column
• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
• B01D 61/14 - Ultrafiltration; Microfiltration

Abstract

A composite membrane comprising (a) a porous support; (b)optionally a gutter layer; (c) a discriminating layer comprising (i) 1 to 99wt% of a polyimide comprising a repeat unit of Formula (1); and (ii) 1 to 99wt% in total of a polyimide comprising a repeat unit of Formula (2) and/or a polymer comprising more than one pendant acrylate group; and (d) optionally a protective layer; wherein L and A are each independently a divalent organic linking group; R1and R2in Formula (2) are each independently H or an alkyl group; and R is a tetravalent linking group other than a group of Formula (I-24) wherein R1and R2in Formula (I-24)are identical to the R1and R2 groups in Formula (2).

IPC Classes  ?

• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• B01D 71/64 - Polyimides; Polyamide-imides; Polyester-imides; Polyamide acids or similar polyimide precursors
• C08L 79/08 - Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors

Abstract

A method for preparing an aqueous solution of a defined pH comprising an acid, a base and optionally one or more additives is provided. The method comprises the steps of: a) calculating the theoretical concentrations of acid and base for the solution to have the defined pH using the Henderson-Hasselbach equation in combination with the Debye Huckel theory for a range of different additive concentrations; b) preparing a sample of the buffer for the range of additive concentrations and measuring the actual pH for each additive concentration; c) calculating a value for delta pH, ?pH, being the difference between the theoretical pH and the actual pH, for each additive concentration; d) generating a mathematical model describing the relationship of ?pH with additive concentration; e) selecting the defined pH and additive concentrations;f) using the mathematical model generated in step d) to calculate ?pH for the defined pH and additive concentration; g) calculating a ?pH-corrected pH by summing the defined pH and delta pH; h) using the ?pH-corrected pH to calculate the concentrations of acid and base using the Henderson-Hasselbach equation in combination with the Debye Huckel theory; i) preparing the solution using the concentrations calculated in step h).

IPC Classes  ?

• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• B01J 47/15 - Controlling or regulating for obtaining a solution having a fixed pH
• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
• G05D 21/02 - Control of chemical or physico-chemical variables, e.g. pH-value characterised by the use of electric means

Abstract

A method for preparing an aqueous solution of a defined pH comprising an acid, a base and optionally one or more additives is provided. The method comprises the steps of: a) calculating the theoretical concentrations of acid and base for the solution to have the defined pH using the Henderson-Hasselbach equation in combination with the Debye Huckel theory for a range of different additive concentrations; b) preparing a sample of the buffer for the range of additive concentrations and measuring the actual pH for each additive concentration; c) calculating a value for delta pH, ∆pH, being the difference between the theoretical pH and the actual pH, for each additive concentration; d) generating a mathematical model describing the relationship of ∆pH with additive concentration; e) selecting the defined pH and additive concentrations;f) using the mathematical model generated in step d) to calculate ∆pH for the defined pH and additive concentration; g) calculating a ∆pH-corrected pH by summing the defined pH and delta pH; h) using the ∆pH-corrected pH to calculate the concentrations of acid and base using the Henderson-Hasselbach equation in combination with the Debye Huckel theory; i) preparing the solution using the concentrations calculated in step h).

IPC Classes  ?

• G01N 30/34 - Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
• G05D 21/02 - Control of chemical or physico-chemical variables, e.g. pH-value characterised by the use of electric means
• B01J 47/15 - Controlling or regulating for obtaining a solution having a fixed pH
• B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier

Abstract

A process for separating a feed gas comprising a polar gas and a non-polar gas into a permeate gas and a retentate gas, one of which is enriched in the polar gas and the other of which is depleted in the polar gas, the process comprising passing the feed gas through a gas separation module comprising: (i) a feed carrier comprising a membrane envelope and a feed spacer located within the membrane envelope; and (ii) a permeate carrier comprising: (a) a macroporous sheet; and (b) a protective sheet; and wherein: i) the feed gas is fed along the feed spacer of the feed carrier and a part of the feed gas passes through the membrane envelope and into the permeate carrier to give the permeate gas and a part of the feed gas is rejected by the membrane to give the retentate gas; ii) the protective sheet shields at least a part of the membrane envelope from contact with the macroporous sheet; and iii) the protective sheet comprises a non-woven material.

IPC Classes  ?

• B01D 63/10 - Spiral-wound membrane modules
• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/10 - Supported membranes; Membrane supports
• B01D 69/12 - Composite membranes; Ultra-thin membranes

Abstract

A method of concentration of a liquid comprising a biomolecule is provided. The method comprises passing the liquid through a tangential flow filtration device under pressure, wherein the pressure applied is varied between at least a higher pressure and a lower pressure. Preferably, the variation in pressure is delivered by the use of a variable flow-controller, such as a valve.

IPC Classes  ?

• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Abstract

Apparatus for in-line liquid exchanging a biomolecule-containing liquid is provided. The apparatus comprises a means (3) for mixing at least two liquids comprising a multiple inlet flow-controller (2), the means for mixing also comprising an outlet in fluid connection with a tangential flow filtration device (1) configured in single-pass mode.

IPC Classes  ?

• B01D 61/18 - Apparatus therefor
• B01D 61/20 - Accessories; Auxiliary operations
• C07K 1/14 - Extraction; Separation; Purification
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 61/16 - Feed pretreatment
• B01D 61/22 - Controlling or regulating

Abstract

A method for generating electricity comprising the steps: (A) passing a concentrated ionic solution through a first pathway in a reverse electrodialysis unit comprising a membrane stack having electrodes and alternating cation and anion exchange membranes; and (B) passing a dilute ionic solution through a second pathway in said reverse electrodialysis unit, whereby solute from the concentrated solution in the first pathway passes through the membranes to the dilute solution in the second pathway, thereby generating electricity; wherein: (i) the concentrated ionic solution and the dilute ionic solution each comprise a main salt; and (ii) the main salt present in each of the concentrated ionic solution and the dilute ionic solution as they enter the reverse electrodialysis unit is such that Equation 1 is satisfied: ACc/ACd is at least 1.5 (Equation 1) wherein ACc and ACd are the activity coefficients of the main salts present in the concentrated and dilute ionic solutions when measured at a concentration of 6 mol/kg water at 25°C and at a concentration of 0.5 mol/kg water at 25°C respectively.

IPC Classes  ?

• H01M 8/22 - Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elements; Fuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen
• B01D 61/42 - Electrodialysis; Electro-osmosis
• C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis

Goods & Services

Cell cultures used in industry and science; mammalian cell cultures and vectors, being independent replicating pieces of DNA that can transfer DNA sequences, each for manufacture and development in the biotechnology industries. Processing and manufacturing of vectors, cell cultures and recombinant proteins for use in biotechnology industries to the order and specification of others; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others. Scientific, industrial and technical research, development and analysis services relating to the use of mammalian cell cultures and vectors in the field of biotechnology; process development, namely, development of processes for the use of mammalian cell cultures and vectors in the manufacture of biotechnology products; project studies relating to the use of mammalian cell cultures and vectors in the field of biotechnology.

Abstract

A protein expression system for use in a prokaryotic host is provided, the expression system comprising: a) an expression cassette comprising a nucleic acid sequence encoding a protein of interest operably linked to a T7 RNA polymerase-dependent promoter; and b) an expression cassette comprising a nucleic acid sequence encoding T7 RNA polymerase operably linked to a host polymerase-dependent λ phage promoter and a single perfect palindrome operator sequence; wherein the expression cassette for T7 RNA polymerase is located on the chromosome of a host cell.

IPC Classes  ?

• C12N 15/67 - General methods for enhancing the expression
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 15/73 - Expression systems using phage lambda regulatory sequences

Abstract

A process for preparing a membrane comprising applying a composition comprising a polyimide to a gas-permeable support and irradiating the composition with UV-C light source to form a discriminating layer on the support, wherein: (i) the UV-C light source emits light having a wavelength in the range 200 to 280nm; (ii) the irradiation is performed for a period of time in the range 0.05 to 60 seconds; and (iii) the irradiation is performed at a power intensity of at least 20 mW/cm2 and no more than 250 mW/cm2

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranes; Membrane supports
• B01D 71/64 - Polyimides; Polyamide-imides; Polyester-imides; Polyamide acids or similar polyimide precursors

Abstract

A hydrogel comprising: water; an alginate; a glucono-delta-lactone (GDL); and micropartides comprising an inorganic calcium compound and recombinant gelatin. The hydrogels may be used for bone repair and/or regeneration.

IPC Classes  ?

• A61L 27/02 - Inorganic materials
• A61L 27/20 - Polysaccharides
• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/52 - Hydrogels or hydrocolloids

Abstract

A composite membrane comprising: (a) a porous support; (b) optionally a gutter layer; (c) a polyimide discriminating layer; and (d) a protective layer comprising dialkylsiloxane groups and having an average thickness of 825 to 2,000 nm; wherein the polyimide discriminating layer comprises 2,4,6-trimethyl-1,3-phenylene groups, each such group independently having an atom or substituent other than H at the 5-position.

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranes; Membrane supports
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• B01D 71/64 - Polyimides; Polyamide-imides; Polyester-imides; Polyamide acids or similar polyimide precursors
• B01D 71/70 - Polymers having silicon in the main chain, with or without sulfur, nitrogen, oxygen or carbon only

Abstract

A process for the production of a target polypeptide is provided. The process comprises expression of an expression vector for expressing a target polypeptide in a host cell, preferably a mammalian cell, the expression vector comprising an expression cassette comprising a polynucleotide encoding a recombinant polypeptide operably linked to a fibronectin secretion leader sequence; and recovering the target polypeptide.

IPC Classes  ?

• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C07K 16/06 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies from serum
• C07K 16/30 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Abstract

An aqueous ink comprising: from 0.1 to 8 parts by weight of a self-dispersible pigment which comprises a carboxy-functional dispersant crosslinked around a pigment core by a crosslinking agent having at least two groups selected from oxetane, carbodiimide, hydrazide, oxazoline, aziridine, isocyanate, N-methylol, keteneimine, isocyanurate and epoxy groups; from 10 to 25 parts by weight of a first solvent selected from one or more of the group consisting of ethylene glycol, propylene glycol, dipropylene glycol and triethylene glycol; from 2 to 10 parts by weight of a second solvent selected from one or more of the group consisting of 2-pyrrolidone, N-methyl-2-pyrrolidone, N-ethyl-2- pyrrolidone, N-cyclohexyl-2-pyrrolidone and N,N-dimethylacetamide; from 20 to 45 parts by weight of glycerol; from 4 to 12 parts by weight of a styrene butadiene latex binder and/or a polyurethane latex binder; from 0.1 to 2 parts by weight of an acetylenic surfactant; from 0 to 2 parts by weight of 1,2-benzisothiazolin-3-one; and the balance to 100 parts by weight water. Also ink-jet printing processes, printed materials, ink containers and ink-sets.

IPC Classes  ?

• C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
• C09D 11/106 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C09D 11/322 - Pigment inks
• C09D 11/38 - Inkjet printing inks characterised by non-macromolecular additives other than solvents, pigments or dyes
• C09D 11/40 - Ink-sets specially adapted for multi-colour inkjet printing

Goods & Services

Self-adhesive boards of foam for mounting pictures, self-adhesive wall decorations, adhesive wall decorations, adhesive plastic film used for mounting images, adhesive corners for photographs, adhesive corners for photographs, paper picture mounts, photo albums and collectors' albums, mounting photographs (apparatus for -); photograph holders. Fastening materials, not of metal (terms considered too vague by the International Bureau - rule 13.2.b) of the Common Regulations), decorations of foam (terms considered too vague by the International Bureau - rule 13.2.b) of the Common Regulations), photograph and picture frames.

Abstract

A process for preparing a composite membrane comprising the steps: a) applying a radiation-curable composition to a porous support; b) irradiating the composition present on the support, thereby forming a gutter layer of cured polymer; c) forming a discriminating layer on the gutter layer; and d) applying a radiation-curable composition to the discriminating layer and irradiating that composition, thereby forming a protective layer on the discriminating layer; wherein one or both of the radiation-curable compositions applied in steps a) and d) comprise a photo acid generator having an absorbency coefficient ε at 313 nm of more than 1x104 mol-1*cm-1. Also claimed are composite membranes and gas separation cartridges comprising the membranes.

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/10 - Supported membranes; Membrane supports
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• B01D 71/16 - Cellulose acetate
• B01D 71/62 - Polycondensates having nitrogen-containing heterocyclic rings in the main chain
• B01D 71/64 - Polyimides; Polyamide-imides; Polyester-imides; Polyamide acids or similar polyimide precursors
• B01D 63/08 - Flat membrane modules
• B01D 63/10 - Spiral-wound membrane modules
• B01D 69/04 - Tubular membranes
• B01D 69/06 - Flat membranes
• B01D 69/08 - Hollow fibre membranes
• B41M 5/52 - Macromolecular coatings
• B01D 71/32 - Polyalkenyl halides containing fluorine atoms
• B01D 71/70 - Polymers having silicon in the main chain, with or without sulfur, nitrogen, oxygen or carbon only

Abstract

Membrane cell stack arrangement comprising a housing, a stack of membranes defining flow compartments and a fluid manifold system, wherein the direction of flow through the flow compartments is different to the direction of flow through entry and exit openings and the width of the entry and exit openings are each larger than 45% of the width of the flow compartment.

IPC Classes  ?

• B01D 61/46 - Apparatus therefor
• B01D 61/50 - Stacks of the plate-and-frame type
• B01D 63/08 - Flat membrane modules

Abstract

An electrode unit comprising: (a)an electrically non-conductive circumferential housing; (b)a current collector; (c)an electrode; (d)optionally a charge barrier;and (e)an electrically conductive connector in electrical contact with the current collector(b); wherein(b), (c) and (d) (when present) are located within the circumference of the circumferential housing (a); the main plane of the part of (e) which is located within the housing (a) is substantially parallel to the main plane of (b), (e)extends beyond the housing (a),the electrode unit further comprises a barrier which prevents fluid passing through a device comprising the electrode unit from coming into contact with the connector (e). Also claimed are stacks, composites devices and their uses.

IPC Classes  ?

• C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis

Abstract

An electrode unit comprising: (a) an electrically non-conductive circumferential housing; (b) a current collector; (c) an electrode; (d) optionally a charge barrier; and (e) an electrically conductive connector in electrical contact with the current collector (b); wherein (b), (c) and (d) (when present) are located within the circumference of the circumferential housing (a); the main plane of the part of (e) which is located within the housing (a) is substantially parallel to the main plane of (b), (e) extends beyond the housing (a); and the area of the part of (e) which is located within the housing (a) is less than 30% of the area of (b). Also claimed are stacks, composites devices and their uses.

IPC Classes  ?

• C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis

Abstract

A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.

IPC Classes  ?

• C12P 21/00 - Preparation of peptides or proteins
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 15/72 - Expression systems using regulatory sequences derived from the lac-operon
• C12N 15/73 - Expression systems using phage lambda regulatory sequences
• C12R 1/19 - Escherichia coli
• C12N 15/78 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
• C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Abstract

A membrane stack comprising the following components: (a) a first ion diluting compartment (D1); (b) a second ion diluting compartment (D2); (c) a first ion concentrating compartment (C1); (d) a second ion concentrating compartment (C2); and (e) a membrane wall (CEM1, mAEM, mCEM, AEM, CEM2) between each compartment and on the outside of the first and last compartment of the stack; wherein: (i) each membrane wall comprises a cation exchange membrane (CEM1, mCEM, CEM2) or an anion exchange membrane (mAEM, AEM) and the order of the cation and anion exchange membranes alternates from each wall to the next; (ii) the membrane walls (mAEM, mCEM) on each side of compartment (a) both have a higher monovalent ion selectivity than the corresponding membrane walls (AEM, CEM2) on each side of compartment (b); and (iii) the stack further comprises a means for communicating fluid between compartments (a) and (b).

IPC Classes  ?

• C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
• C02F 1/46 - Treatment of water, waste water, or sewage by electrochemical methods
• B01D 61/44 - Ion-selective electrodialysis
• B01D 61/58 - Multistep processes
• B01D 61/50 - Stacks of the plate-and-frame type
• B01D 63/08 - Flat membrane modules
• B01D 69/06 - Flat membranes
• C02F 103/08 - Seawater, e.g. for desalination
• C02F 1/52 - Treatment of water, waste water, or sewage by flocculation or precipitation of suspended impurities
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 1/42 - Treatment of water, waste water, or sewage by ion-exchange
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption

Abstract

A method of concentration of a liquid comprising a biomolecule is provided. The method comprises passing the liquid through a tangential flow filtration device under pressure, wherein the pressure applied is varied between at least a higher pressure and a lower pressure. Preferably, the variation in pressure is delivered by the use of a variable flow- controller, such as a valve.

IPC Classes  ?

• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Abstract

Apparatus for in-line liquid exchanging a biomolecule-containing liquid is provided. The apparatus comprises a means (3) for mixing at least two liquids comprising a multiple inlet flow-controller (2), the means for mixing also comprising an outlet in fluid connection with a tangential flow filtration device (1) configured in single-pass mode.

IPC Classes  ?

• B01D 61/18 - Apparatus therefor
• B01D 61/20 - Accessories; Auxiliary operations
• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

Abstract

A method of concentration of a liquid comprising a biomolecule is provided. The method comprises passing the liquid through a tangential flow filtration device under pressure, wherein the pressure applied is varied between at least a higher pressure and a lower pressure. Preferably, the variation in pressure is delivered by the use of a variable flow- controller, such as a valve.

IPC Classes  ?

• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Abstract

Apparatus for in-line liquid exchanging a biomolecule-containing liquid is provided. The apparatus comprises a means (3) for mixing at least two liquids comprising a multiple inlet flow-controller (2), the means for mixing also comprising an outlet in fluid connection with a tangential flow filtration device (1) configured in single-pass mode.

IPC Classes  ?

• B01D 61/18 - Apparatus therefor
• B01D 61/20 - Accessories; Auxiliary operations
• C07K 1/34 - Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Abstract

Membrane cell stack arrangement and method of manufacturing such a membrane cell stack arrangement. The arrangement has a housing (2) having a central axis, and a stack of membrane cells (4), each membrane cell (6) being arranged inside the housing (2) with a major surface (6a) of the membrane cell (6) oriented substantially perpendicular to the central axis. Each membrane cell (6) has a corner recess (12) between each two adjacent sides of at least four sides (10a-d). Sealing compartments (14) are provided by corner recesses (12) of adjacent membrane cells of the stack of membrane cells (4) in co-operation with a part of an inner surface (2a) of the housing (2).

IPC Classes  ?

• B01D 63/08 - Flat membrane modules
• B01D 65/00 - Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes

Abstract

A gas-separation module comprising: a) a permeate collection tube comprising a hollow cylinder provided with perforations oriented along the longitudinal axis of the cylinder; and b) at least seven membrane envelopes wound spirally around the permeate collection tube; wherein: (i) the membrane envelopes each comprise a feed spacer and gas- separation membrane(s), wherein the feed spacer is disposed between the gas-separation membrane(s) to define a feed channel and wherein the feed spacer comprises a polymer having a Tg above 0°C; (ii) the module comprises a permeate channel between each of the membrane envelopes in gas-communication with the perforations; and (iii) the permeate collection tube and the membrane envelopes are disposed such that when the module is in use, feed gas entering the feed channel can pass through the perforations only after passing through the gas- separation membranes from the feed channel to the permeate channel. Also claimed are gas separation units and a process for separating gases.

IPC Classes  ?

• B01D 63/10 - Spiral-wound membrane modules

Abstract

A process for printing on a textile substrate comprising the steps of: (I) preparing an ink comprising the following components: (a) from 1 to 8 parts of a self-dispersible pigment which comprises a carboxy-functional dispersant crosslinked around a pigment core by a crosslinking agent having at least two groups selected from oxetane, carbodiimide, hydrazide, oxazoline, aziridine, isocyanate, N-methylol, keteneimine, isocyanurate and epoxy groups; (b) from 0 to 16 parts of a binder selected from one or more of an acrylic latex binder, a styrene acrylic latex binder and a styrene butadiene latex binder wherein the binder has a Tg in the range of from -25°C to 35°C; (c) from 1 to 30 parts of one or more water-miscible organic solvents (d) from 0.1 to 3 parts of a surfactant; (e) from 0 to 5 parts of biocide; (f) from 0 to 10 parts of a viscosity modifier; (g) from 0 to 10 parts of a polyurethane latex binder with a Tg in the range of from -25°C to 35°C; (h) from 0 to 6 parts of a cross linking agent; and (i) the balance to 100 parts water: (II) optionally preparing a latex binders solution comprising; i) from 1 to 16 parts of one or more latex binders selected from an acrylic latex binder, a styrene acrylic latex binder and a styrene butadiene latex binder where the latex binder(s) have a Tg in the range of from -25°C to 35°C; ii) from 0 to 6 parts of a polyurethane latex binder; and iii) from 0 to 5 parts of a cross linking agent: (III) printing the ink prepared in step (I) on to a textile substrate using a ink jet printer with a single pass print head and optionally pre-printing or overprinting with the latex binder solution from step (II) (IV) curing the printed textile substrate from step (III): provided that if component (b) in the ink prepared in step (a) is 0 then optional step (II) is compulsory. Also inks, ink-sets, ink containers and ink-jet printers.

IPC Classes  ?

• D06P 5/30 - Ink jet printing
• C09D 11/106 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C09D 11/322 - Pigment inks
• C09D 11/40 - Ink-sets specially adapted for multi-colour inkjet printing
• B41M 7/00 - After-treatment of printed works, e.g. heating, irradiating

Goods & Services

Self-adhesive boards of foam for mounting pictures, self-adhesive wall decorations, Adhesive wall decorations, Adhesive plastic film used for mounting images, Adhesive corners for photographs, Adhesive corners for photographs, Paper picture mounts, Photo albums and collectors' albums, Mounting photographs (Apparatus for -). Fastening materials, not of metal, photograph holders, decorations of foam, photograph and picture frames.

Abstract

A radiation-curable composition comprising: a)10 to 65 wt% of curable ionic compound(s) comprising one ethylenically unsaturated group; b)3 to 60 wt% of crosslinking agent(s) comprising at least two ethylenically unsaturated groups and having a number average molecular weight below 800; c)5 to 55 wt% of inert solvent(s) having a boiling point above 100°C; d)0 to 10 wt% of free-radical initiator(s); and e)0.5 to 25wt% of thickening agent(s).

IPC Classes  ?

• B01D 61/44 - Ion-selective electrodialysis
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/12 - Composite membranes; Ultra-thin membranes

Abstract

A process for preparing an encapsulated pigment dispersion suitable for use in an ink jet printing ink comprising the following steps in the order I) followed by II): I)providing a dispersion comprising a pigment, a liquid medium and a dispersant having a WAMW of up to 50,000 Daltons obtained by copolymerising a monomer composition comprising components a) and b): a) from 75 to 97 parts of one or more hydrophobic ethylenically unsaturated monomers comprising at least 50 parts benzyl (meth) acrylate; and b) from 3 to 25 parts one or more hydrophilic ethylenically unsaturated monomers having one or more ionic group(s); wherein the parts are by weight and the sum of the parts a) and b) add up to 100; II) cross-linking the dispersant in the presence of the pigment and the liquid medium.

IPC Classes  ?

• C09D 11/107 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds from unsaturated acids or derivatives thereof
• B01F 17/00 - Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
• C09D 11/322 - Pigment inks
• C09D 11/326 - Pigment inks characterised by the pigment dispersant
• C09B 67/00 - Influencing the physical, e.g. the dyeing or printing, properties of dyestuffs without chemical reaction, e.g. by treating with solvents; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films

Abstract

A composite ion exchange membrane obtainable by a process comprising reacting an ionically-charged membrane with a composition comprising: (a) a monofunctional ethylenically unsaturated monomer having an ionic charge opposite to the charge of the ionically-charged membrane; and (b) a crosslinking agent comprising two or more ethylenically unsaturated groups; wherein the molar ratio of (b):(a) is lower than 0.04 or is zero.

IPC Classes  ?

• C08J 5/22 - Films, membranes or diaphragms
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 71/40 - Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
• C08J 7/18 - Chemical modification with polymerisable compounds using wave energy or particle radiation

Abstract

A method for printing on a water-soluble material which comprises the following steps: a) ink jet printing an ink onto a water-soluble material so as to form an image wherein the ink comprises a self-dispersible pigment which comprises a carboxy-functional dispersant crosslinked around a pigment core by a cross-linking agent having at least two groups selected from oxetane, carbodiimide, hydrazide, oxazoline, aziridine, isocyanate, N-methylol, keteneimine, isocyanurate and epoxy groups; b) overprinting the image formed in step A) with a water soluble overprint varnish, also printed material and inks. Also inks, ink-sets and printed water-soluble material.

IPC Classes  ?

• C09D 11/326 - Pigment inks characterised by the pigment dispersant
• C09D 11/54 - Inks based on two liquids, one liquid being the ink, the other liquid being a reaction solution, a fixer or a treatment solution for the ink
• C09D 11/40 - Ink-sets specially adapted for multi-colour inkjet printing
• B41M 7/00 - After-treatment of printed works, e.g. heating, irradiating
• C09D 11/322 - Pigment inks

Abstract

A composite ion exchange membrane comprising a cationically-charged membrane and an oppositely charged compound covalently bound thereto, the composite ion exchange membrane having: (i) a zeta-potential lower than -8mV; and (ii) an effective charge lower than 20µmol/m2.

IPC Classes  ?

• C08J 5/22 - Films, membranes or diaphragms
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 71/40 - Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
• C08J 7/18 - Chemical modification with polymerisable compounds using wave energy or particle radiation

Abstract

A composite membrane comprising: (A) a porous support; (B) optionally a gutter layer; (C) a first discriminating layer; (D) an outermost layer; and (E) a non-discriminating layer interposed between the first discriminating layer (C) and the outermost layer (D); wherein the outermost layer (D) is a discriminating layer comprising a polyimide polymer.

IPC Classes  ?

• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• B01D 71/70 - Polymers having silicon in the main chain, with or without sulfur, nitrogen, oxygen or carbon only

Abstract

A curable composition comprising the components (i) 0 to 60 wt% non-ionic crosslinker(s); (ii) 20 to 85 wt% curable ionic compound(s) comprising an anionic group and at least one ethylenically unsaturated group; (iii) 15 to 45 wt% solvent(s); (iv) 0 to 10 wt% of photoinitiator(s); and (v) 2 to 45 wt% of structure modifier(s); wherein the molar ratio of component (v) : (ii) is 0.25 to 0.65. The compositions are useful for preparing membranes for (reverse) electrodialysis.

IPC Classes  ?

• C08F 2/10 - Aqueous solvent
• C08F 220/58 - Amides containing oxygen in addition to the carbonamido oxygen
• B01D 61/44 - Ion-selective electrodialysis
• B01D 69/10 - Supported membranes; Membrane supports
• C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
• C09D 133/14 - Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen

Abstract

A method for preparing a transparent sheet material comprising an organic, polymeric substrate and inorganic layers on each side of the substrate, the method comprising the steps of: a)providing an apparatus for generating a glow discharge plasma, said apparatus comprising at least two opposing electrodes, a power supply for the electrodes and a treatment space between the electrodes; b)providing the treatment space with a gas mixture at about atmospheric pressure, the gas mixture comprising a reactive gas and a precursor; and c)moving a transparent substrate through the treatment space comprising the gas mixture at an average speed of at least 1 m/min while applying an electrical potential across the electrodes, thereby generating a glow discharge plasma in the treatment space and depositing an inorganic layer on one or both sides of the substrate; wherein the electrodes apply a discharge energy to the substrate of less than 25 J/cm2.

IPC Classes  ?

• C23C 16/40 - Oxides
• C23C 16/515 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes characterised by the method of coating using electric discharges using pulsed discharges
• C23C 16/54 - Apparatus specially adapted for continuous coating
• H01J 37/32 - Gas-filled discharge tubes
• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
• C08J 7/00 - Chemical treatment or coating of shaped articles made of macromolecular substances

Abstract

A transparent sheet material comprising an organic, polymeric substrate and inorganic layers on each side of the substrate, wherein the overall thickness of the inorganic layer(s) on each side of the substrate is less than 5nm

IPC Classes  ?

• C23C 16/509 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes characterised by the method of coating using electric discharges using radio frequency discharges using internal electrodes
• C23C 16/54 - Apparatus specially adapted for continuous coating
• C23C 16/30 - Deposition of compounds, mixtures or solid solutions, e.g. borides, carbides, nitrides

Abstract

An ink comprising: (a) from 0.5 to 5 parts of a self-dispersible pigment; (b) from 1 to 10 parts of a styrene acrylic latex binder and/or styrene butadiene latex; (c) from 0 to 5 parts of a glycol selected from the group consisting of ethylene glycol, diethylene glycol, propylene glycol,dipropylene glycolor triethylene glycol; (d) from 1 to 10 parts of 2-pyrrolidone; (e) from 1 to 15 parts of glycerol; (f) from 0.1to 3 parts of an acetylenic surfactant; (g) from 0.001 to 5 parts of biocide; (h) from 0 to 10 parts of a viscosity modifier; and (i) the balance to 100 parts water. Also an ink-jet printing process, a printed substrate, an ink-jet printer ink container and an ink-jet printer with a re-circulating printer head.

IPC Classes  ?

• C09D 11/106 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C09D 11/322 - Pigment inks
• C09D 11/38 - Inkjet printing inks characterised by non-macromolecular additives other than solvents, pigments or dyes

Abstract

An ink comprising: (a)from 1to25 parts of titanium dioxide pigment; (b)from 0to 8parts of a styrene butadiene latex binder; (c)from 0 to 8 parts of a polyurethane latex binder; (d)from 0 to 5 parts of a glycol selected from the group consisting of ethylene glycol, diethylene glycol, propylene glycol,dipropylene glycolor triethylene glycol; (e)from 1 to 10 parts of 2-pyrrolidone; (f)from 1 to 10 parts of glycerol; (g)from 0.01to 2parts ofan acetylenic surfactant; (h)from 0.001 to 5 parts of biocide; (i)from 0 to 10 parts of a viscosity modifier; and (j)the balance to 100 parts water; provided that (b) plus (c) is greater than 0. Also ink jet printing processes, ink-jet ink containers, printed substrates and ink-jet printers.

IPC Classes  ?

• C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
• C09D 11/106 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C09D 11/322 - Pigment inks
• C09D 11/38 - Inkjet printing inks characterised by non-macromolecular additives other than solvents, pigments or dyes

Abstract

An ink comprising: (a) 0.5to 5parts of a self-dispersible pigment; (b) 2 to 8parts of a styrene acrylic latex binderand/or a styrene butadiene latex binder; (c) 0.5 to 5 parts of a polyurethane latex binder; (d) 0 to 5 parts of a glycol selected from the group consisting of ethylene glycol, diethylene glycol, propylene glycol,dipropylene glycolor triethylene glycol; (e) 1 to 10 parts of 2-pyrrolidone; (f) 1 to 15 parts of glycerol; (g) 0.1to 3 parts ofacetylenic surfactant; (h) 0.001 to 5 parts of biocide; (i) 0 to 10 parts of a viscosity modifier; and (j) the balance to 100 parts water. Also ink jet printing processes, ink-jet ink containers,printed substrates and ink-jet printers.

IPC Classes  ?

• C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
• C09D 11/106 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C09D 11/322 - Pigment inks
• C09D 11/38 - Inkjet printing inks characterised by non-macromolecular additives other than solvents, pigments or dyes

Abstract

A process for the production of a target polypeptide is provided. The process comprises expression of an expression vector for expressing a target polypeptide in a host cell, preferably a mammalian cell, the expression vector comprising an expression cassette comprising a polynucleotide encoding a recombinant polypeptide operably linked to a fibronectin secretion leader sequence; and recovering the target polypeptide.

IPC Classes  ?

• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C07K 16/06 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies from serum
• C07K 16/30 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Abstract

An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.

IPC Classes  ?

• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 15/62 - DNA sequences coding for fusion proteins

Abstract

A process for printing on a water-soluble material using a self-dispersible pigment which comprises a carboxy-functional dispersant crosslinked around a pigment core by a crosslinking agent having at least two groups selected from oxetane, carbodiimide, hydrazide, oxazoline, aziridine, isocyanate, N-methylol, keteneimine, isocyanurate and epoxy groups. Also inks, ink-sets, printed material and ink-jet printers.

IPC Classes  ?

• C09D 11/00 - Inks
• C09D 11/30 - Inkjet printing inks
• C09D 11/322 - Pigment inks
• C09D 11/324 - Pigment inks containing carbon black
• C09D 11/326 - Pigment inks characterised by the pigment dispersant
• C09D 11/40 - Ink-sets specially adapted for multi-colour inkjet printing

Goods & Services

(1) Storage archive appliances, namely hard disk drive, computer hardware for tape drives and computer software for database management for data processing equipment, namely data processing software, computer file management programs, computer terminals for data processing. (1) Collating, systematic ordering, updating and storage of data in a computer database; organizational project management in the field of electronic data processing; electronic data storage (2) Physical storage of electronically-stored data or documents (3) Editing, formatting and transfer of data on to blank CDs (premastering); electronic data security; conversion of data or documents from physical to electronic media; technical project management in the field of electronic data processing; recovery of computer data

Abstract

A method for preparing an ionically-charged membrane comprising the steps (1) applying a film of curable composition to a support; (2) curing the film of curable composition to give anionically-charged membrane; and (3) removing the ionically-charged membrane from the support; wherein the curable composition comprises a) 5 to 50wt% of curable compound comprising one ethylenically unsaturated group and anionic group; b)10 to 70wt% of crosslinking agent comprising at least two ethylenically unsaturated groups and having a molecular weight of at least 500 dalton per ethylenically unsaturated group; and c) 5 to 60wt% of inert solvent.

IPC Classes  ?

• C08F 222/10 - Esters
• C08J 5/22 - Films, membranes or diaphragms
• B01D 61/44 - Ion-selective electrodialysis

Abstract

A process for preparing a membrane stack comprising the steps of: (i)interposing a curable adhesive between alternate anion exchange membranes and cation exchange; and (ii)curing the adhesive; CHARACTERISED IN THAT said adhesive, when cured, has a Shore A hardness of less than 70 and an elongation at break of at least 50%.

IPC Classes  ?

• B01D 61/50 - Stacks of the plate-and-frame type
• B01D 65/00 - Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes

Abstract

A process for preparing a membrane stack comprising the steps of (i) interposing a curable adhesive between alternate anion exchange membranes and cation exchange; and (ii) curing the adhesive; CHARACTERISED IN THAT said membranes are in a swollen state when step (ii) is performed.

IPC Classes  ?

• B01D 61/50 - Stacks of the plate-and-frame type
• B01D 65/00 - Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes

Abstract

II) cross-linking the dispersant in the presence of the pigment and the liquid medium.

IPC Classes  ?

• C09D 11/326 - Pigment inks characterised by the pigment dispersant
• C09B 67/00 - Influencing the physical, e.g. the dyeing or printing, properties of dyestuffs without chemical reaction, e.g. by treating with solvents; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
• C09D 11/322 - Pigment inks
• C09B 67/08 - Coated particulate pigments or dyes
• C09B 67/46 - Dispersions
• C09B 67/54 - Separation; Purification
• C09B 67/02 - Dyestuff preparations characterised by special physical forms, e.g. tablets, films
• C08K 5/1515 - Three-membered rings

Abstract

A disposable, crossflow membrane stack suitable for use in an ion exchange unit, the stack comprising alternate dilution compartments and concentration compartments, each compartment being defined by a flat cation-permeable membrane (2) and a flat anion-permeable membrane (1) and at least two edges along which the cation- permeable and an anion-permeable membranes are permanently secured together wherein the cation-permeable membranes and/ or the anion-permeable membranes have a textured surface profile which keep said membranes apart and/or from touching each other and wherein the edges secured together define the direction in which liquid may flow through the compartments. Also claimed are ion exchange units comprising the stack, optionally comprising a quick- release securement means to allow facile attachment and release of modular units comprising the stacks.

IPC Classes  ?

• B01D 61/50 - Stacks of the plate-and-frame type
• B01D 63/08 - Flat membrane modules

Abstract

A process for preparing an ion-exchange membrane having a textured surface profile comprising the steps(i) and (ii): (i) screen-printing a radiation-curable composition onto a membrane in a patterned manner; and (ii) irradiating and thereby curing the printed, radiation-curable composition; wherein the radiation-curable composition has a viscosity of at least 30 Pa.s when measured at a shear rate of 0.1 s-1 at 20°C.

IPC Classes  ?

• C08J 5/22 - Films, membranes or diaphragms
• B01D 61/42 - Electrodialysis; Electro-osmosis
• C08J 7/04 - Coating

Goods & Services

Magnetic encoders, Data processing apparatus, reading devices, Magnetic tape units for computers, Magnetic data carriers, Optical data carriers, Scanners [data processing equipment], Computer memory devices, Processors (central processing units); Software for reading, systemizing, indexing, recovering, converting and processing stored data. Collating, systematic ordering, updating and storage of data in a computer database; Organizational project management in the field of electronic data processing. Storage (Physical -) of electronically-stored data or documents. Editing, formatting and transfer of data on to blank CDs (premastering); Electronic data back-up; Conversion of data or documents from physical to electronic media; Technical project management in the field of electronic data processing; Recovery of computer data; Electronic data storage.

Goods & Services

Cell cultures used in industry and science; mammalian cell cultures and vectors, being independent replicating pieces of DNA that can transfer DNA sequences, each for manufacture and development in the biotechnology industries. Processing and manufacturing of vectors, cell cultures and recombinant proteins for use in biotechnology industries to the order and specification of others; manufacture, processing and production of recombinant proteins for use in the biotechnology industries to the order and specification of others. Scientific, industrial and technical research, development and analysis services relating to the use of mammalian cell cultures and vectors in the field of biotechnology; process development, namely, development of processes for the use of mammalian cell cultures and vectors in the manufacture of biotechnology products; project studies relating to the use of mammalian cell cultures and vectors in the field of biotechnology.

Abstract

A process for the production of a target polypeptide is provided. The process comprises expressing an expression cassette for the target recombinant polypeptide comprised in a vector in a non-mammalian host, wherein the host is auxotrophic for methionine and lacks the ability to express functional chromosomal Vitamin B12 independent homocysteine methyltransferase. The vector comprises an expression cassette for functional Vitamin B12 independent homocysteine methyltransferase and the host is cultured in a growth medium lacking methionine.

IPC Classes  ?

• C12N 15/65 - Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers

Abstract

A gas separation module comprising gas separation elements, said elements comprising at least two membrane sheets and a permeate carrier sandwiched between the membrane sheets, wherein the permeate carrier comprises at least two macroporous layers and a gas-impermeable sheet located between the macroporous layers.

IPC Classes  ?

• B01D 63/10 - Spiral-wound membrane modules
• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion

Abstract

A gas separation module comprising one or more gas separation elements, said elements comprising at least two membrane sheets and a permeate carrier sandwiched between the membrane sheets, wherein the contact area of the membrane sheets with the permeate carrier is less than 50%.

IPC Classes  ?

• B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 63/10 - Spiral-wound membrane modules

Abstract

A composite gas membrane comprising: a) a porous support; b) an activated gutter layer; c) a discriminating layer located on the gutter layer;and d)optionally a protective layer on the discriminating layer; wherein the said layers remain in place when a peeling force of 2.5 N/1.5 cm is applied to the outermost of said layers.

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/10 - Supported membranes; Membrane supports
• B01D 69/12 - Composite membranes; Ultra-thin membranes
• B01D 71/64 - Polyimides; Polyamide-imides; Polyester-imides; Polyamide acids or similar polyimide precursors