Fast quantitative NMR data acquisition for NMR scans performed on a sample is provided. Scan batches on the sample are performed, where each batch comprises a long delay scan, followed by a set of short delay scans. Each scan is associated with a corresponding scan time point in relation to the long delay scan time point of the respective scan batch. For each corresponding scan time point, aggregated NMR spectrum portions are determined showing a decay over time, which is fitted with an exponential decay function. An averaged integral loss is computed for each scan time point. For each NMR spectrum of the scan batches, an integral associated with a respective region of interest is multiplied with a corresponding correction factor. The integrals associated with the corrected NMR spectra are summed to obtain a representation of the NMR signal intensity in the region of interest for the sample.
coilcoilrampcoilrampcoilcoiltargetcoil targettarget; (e) deactivating the current supply to the coil system and stopping the automatic current charging program. The magnet coil system can thus be autonomously charged with electric current.
G01R 33/38 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
G01R 33/3815 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
H01F 6/02 - QuenchingProtection arrangements during quenching
The invention relates to a permanent magnet system having a magnet array (1) which is arranged annularly about a z axis in order to produce a homogeneous magnetic field in a direction perpendicular to the z axis in a measuring volume (0) inside the annular magnet array, said array having at least one annular magnet element (2) with magnetic material in a plane of the ring, and having, in a Halbach configuration, a number n of juxtaposed individual magnet segments (3), each in surface contact, which according to the rules of a Halbach array have changing magnetization directions when rotating about the annular magnet element and which together produce a magnetic dipole field in the plane of the ring of the annular magnet array, and that each have the same polyhedron geometry and that each have an identical, convex, regular polygonal cross-section. Such a permanent magnet system is characterized in that in the plane of the ring each magnet segment has a convex, regular pentagonal or heptagonal or octagonal cross-section that is identical among them. The permanent magnet system is manufactured in a streamlined and automated method, with considerably improved material efficiency and magnetic flux density being produced by means of the Halbach ring.
A system (100), method and computer program product for generating a data record of a training dataset (140) set configured to train a neural network (230) for determination of the concentration (215c) of a particular target molecule in an NMR sample (201). An NMR spectrum (213) associated with a known concentration (c1) of the target molecule is obtained. The obtained NMR spectrum is adjusted by applying a random shift to generate an adjusted NMR spectrum (213a). A background generator 132 adds a background spectrum which reflects contributions of impurities in the NMR sample. The resulting NMR spectrum together with the information about the concentration of the target molecule is then stored as a new data record of the training dataset (140).
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
09 - Scientific and electric apparatus and instruments
Goods & Services
High field magnetic resonance spectrometers and their main components and accessories, including electronics cabinets/consoles, superconducting and permanent magnets, magnetic resonance probes and RF components, refrigeration equipment and sample handling equipment.
7.
RELATIVE TILT ANGLE ADJUSTMENT SYSTEM FOR MAGNETIC COMPONENTS
An adjustment apparatus for adjusting the angular tilt of a first component of a magnetic circuit relative to an alignment axis of a second component of the circuit uses at least one pair of spacers each of which has a thickness that changes continuously around its periphery. The spacers are arranged between the circuit components and, as a relative rotation between the spacers is changed, the combined thickness of the two spacers increases in one area, while decreasing in another. This results in a tilting of a top surface of the spacer pair relative to a bottom surface, and a corresponding change in a relative tilt of the first component relative to the second component. The spacers may be ring-shaped or disc-shaped, and allow for precise alignment of the magnetic circuit without the need for shims between the components.
36 - Financial, insurance and real estate services
39 - Transport, packaging, storage and travel services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Brokering of business contacts; brokering of commercial transactions; laboratory contracting services; laboratory exchange services; business intermediary and broker services for the provision of analytical services, laboratory contracting services, laboratory exchange services. Financial affairs; monetary affairs; brokering services in general; brokering services in finance. Transport; packaging and storage of goods; brokerage of goods transportation; brokerage of transportation services; brokerage of delivery, collection, transport, forwarding and courier services; brokerage of collection, transport, delivery, forwarding and courier services relating to goods, packages, parcels, documents. Analytical services; analytical laboratory services; laboratory services; consulting in laboratory testing; advisory services related to scientific instruments; brokerage of scientific and technological services; platform-as-a-service (PAAS) services; providing an online non downloadable, web-based and cloud-based software platform; providing an online non-downloadable, web-based, and cloud-based connected software platform that facilitates the provision of information, peer-to-peer interaction and transactions, and bookings in the fields of analytical services, analytical laboratory services, laboratory services, laboratory testing, services related to scientific instruments; software-as-a-service (SAAS) services; brokerage of consulting services, namely analytical laboratory services and scientific instruments related services.
The invention relates to a superconducting magnetic coil system having a first electric mesh (M1) and a second electric mesh (M2), which are connected to one another in series, wherein the first electric mesh (M1) comprises, in a first path, a HTS (high temperature superconductor) coil section (A0) and a main coil section (A1) connected in series therewith and, in a second path, a quenching protection element (Q1), which bypasses the series connection of the HTS coil section (A0) and first main coil section (A1). The first main coil section (A1) comprises a conductor with superconducting filaments in a matrix. The second electric mesh (M2) comprises an adjacent main coil section (A3) having a conductor with superconducting filaments in a matrix. The adjacent main coil section (A3) is that main coil section of an electric mesh other than the first electric mesh that is closest to the first main coil section (A1) of the first electric mesh in the outward radial direction. The magnetic coil system is characterised in that, in the event of quenching, the conductors of the main coil sections (A1, A3, A4) each generate a specific power input (LT/2ϖ)2*MM, wherein the specific power input of the conductor of the first main coil section (A1) of the first electric mesh (M1) is higher than the specific power input of the conductor of the adjacent main coil section (A3) of the second electric mesh (M2). With the use of HTS superconducting material, a magnetic coil system can therefore be provided with which particularly high field strengths can be generated, and/or which has a small overall size.
A cryostat arrangement (1′) having a vacuum container (2) and an object (4) to be cooled, which is arranged inside the vacuum container. A neck tube (8) leads to the object, and a cooling arm (10) of a cold head (11), around which a closed cavity (9) is formed, is arranged in the neck tube, which is sealed off fluid-tight in relation to the object and is filled with cryogenic fluid in normal operation. A thermal coupling element (15) couples the cryogenic fluid in the cavity to the object. A pump device (14), to which the cavity is connected via a valve (13) and with which the cavity is pumped out if the cold head fails. A monitoring unit (17) monitors the cooling function of the cold head, and activates the pump device to pump out the cavity if the cooling function of the cold head drops.
The invention relates to an MRI system (1) comprising: a cryostate (2) with a vacuum container (8) and a cryo container (10) in which a superconducting magnetic coil system (12) for generating a magnetic field (B0) in a sample volume (7), in the room temperature bore (3) of the cryostat (2) is arranged; an HF coil system (6) in the room temperature bore (3) for generating and capturing HF-signals in or outside of the sample volume (7) ; a gradient coil system (4) in the room temperature bore (3) for generating magnetic field gradients in the sample volume (7) and a screening tube arrangement (5) which is made at least partially from an electrically conductive material, the screening tube arrangement (5) being arranged radially about the gradient coil system (4). The invention is characterised in that the screening tube arrangement (5) has a gap structure (15) with a plurality of gaps (16: 26) which extend at least over one part of the radial depth of the screening tube arrangement (5) such that the gaps (16:26) are distributed axially and azimutally on the screening tube arrangement (5) and that the profiles of the gaps (16:26) have parts in the axial direction and parts in the azimutal direction. The invention also relates to an MRI system in which the effects of mechanical oscillations of the gradient coil system can be reduced more easily and in a better matter.
A cryostat arrangement (V) comprising a vacuum container (2) and an object being cooled (4), which object being cooled is arranged within the vacuum container which has a neck tube (8) which leads to the object being cooled, wherein a cooling arm (10) of a cold head (11) around which a closed cavity (9) is formed is arranged in the neck tube which is sealed off in a fluid-tight manner from the object being cooled and is filled with cryogenic fluid during normal operation, and wherein a thermal coupling means (15) is provided, this being suitable for thermally coupling the cryogenic fluid in the cavity to the object being cooled, is characterized in that the cryostat arrangement comprises a pump apparatus (14) to which the cavity is connected via a valve (13) and with which the cavity can be emptied in the event of a drop in the cooling function of the cold head, and in that a monitoring device (17) is provided, said monitoring device monitoring the cooling function of the cold head and being designed to automatically activate the pumping apparatus in the event of a drop in the cooling function of the cold head so that the cavity is drained. Therefore, the object being cooled can be automatically kept in the vicinity of the operating temperature during a bridging time.
G01R 33/3815 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
13.
METHOD FOR PREDICTING CHEMICAL SHIFT VALUES OF NMR SPIN SYSTEMS IN A SAMPLE OF A FLUID CLASS, IN PARTICULAR IN A SAMPLE OF A BIOFLUID
A method for predicting chemical shift values of NMR spin systems belonging to compounds contained in a sample of a fluid class using NMR spectroscopy, with the following steps: a) providing a model appliance representing a correlation information between captured characteristics of the fluid class, including concentrations of captured substances contained in the fluid class, and chemical shift values of captured NMR spin systems belonging to compounds contained in the fluid class, with said compounds being among said captured substances, wherein the model appliance comprises a definition of reference NMR spin systems, with the reference NMR spin systems being a subset of the captured NMR spin systems, with the reference NMR spin systems belonging to compounds which are omnipresent in the fluid class, b) recording an NMR spectrum of the sample of the fluid class; c) identifying peaks in the recorded NMR spectrum which belong to the defined reference NMR spin systems of the model appliance, and determining experimental chemical shift values of said peaks from the recorded NMR spectrum; d) predicting a chemical shift value (30) of at least one of the captured NMR spin systems not belonging to the reference NMR spin systems by applying the model appliance onto the experimental chemical shift values (10) of the reference NMR spin systems. The invention allows a more reliable and easier, in particular faster, attribution of peaks in an NMR spectrum of a sample of a fluid class, in particular biofluid, to NMR spins systems of compounds contained in the sample.
37 - Construction and mining; installation and repair services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Repair and installation services for apparatus or instruments for scientific measuring; installation, maintenance and repair of apparatus, instruments and equipment including computer hardware for purposes for scientific measuring and of evaluating measurement data, in particular service and life cycle support for said apparatus; instruments and equipment including service activities that are requested by customers during the lifecycle of their apparatus or instruments such as maintenance and repairing including the replacement of parts and supporting with products that are required for operational use like consumables, accessories and qualified original spare parts. Education and providing of training, in particular education and training programs to provide knowledge for the operation and application of modern analytical instrumentation. Scientific and technological services and research and design relating thereto; design and development and maintenance of computer software for purposes of evaluating measurement data, in particular service activities that are requested by customers during the lifecycle of their apparatus or instruments such as remote monitoring, remote desktop support and/or assistance on site, support and assistance to adjust settings and parameters in order to correct and maintain optimal performance of the instrument, application developments and support, instrument upgrades and enhancements; design and development of computer hardware for purposes of evaluating measurement data.
15.
CRYOSTAT HAVING A FIRST AND A SECOND HELIUM TANK, WHICH ARE SEPARATED FROM ONE ANOTHER IN A LIQUID-TIGHT MANNER AT LEAST IN A LOWER PART
The invention relates to a cryostat (20) for supercooled (< 2.5 K) liquid helium which is typically used for cooling a superconducting magnet coil (6), which cryostat (20) comprises two helium tanks (24, 5), which do not communicate with one another with regard to the respectively contained liquid helium. A Joule-Thomson cooling unit (2) having a heat exchanger (38) in the lower part (1) of the first helium tank (24) uses liquid helium (> 4 K) stored in the second helium tank (5) in order to cool the supercooled liquid helium in the lower part (1) of the first helium tank (24). For this the Joule-Thomson cooling unit (2) either draws in liquid helium directly from the second helium tank (5), or the Joule-Thomson cooling unit (2) draws in liquid helium from the first helium tank (24), typically from an upper part (4) having liquid helium (> 4 K), and liquid helium can be transferred via the gas phase from the second helium tank (5) into the first helium tank (5). In this way the period of time in which the supercooled liquid helium of the first helium tank (24) can be cooled by means of a helium stock in the cryostat (20) can be arranged to be very long. The second helium tank (5) can be arranged at least partially adjacent to the first helium tank (24), in particular also around the first helium tank (24), in order to achieve a low overall height of the cryostat (20).
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific instruments, namely, analyzers for testing and analyzing food and beverages Measurement and analysis of quality and/or composition of food and beverages
17.
PULSE TUBE COOLER SYSTEM WITH FORCE-COMPENSATED ROTARY VALVE LINE
A pulse tube cooler system (10), comprising a cold head (2), a control valve (3) and a connection device (4), wherein, using the control valve (3), it is possible to switch in alternation between a high-pressure reservoir (81) and a low-pressure reservoir (82) of a working gas via the connection device (4) to the cold head (2), and wherein the connection device (4) is split into a first line branch (11) and a second line branch (12), is characterized in that the first line branch (11) has a first flexible line section (4a) and the second line branch (12) has a second flexible line section (4b), in that the flexible line sections (4a, 4b) are arranged parallel to one another and are offset with respect to one another perpendicular to a longitudinal direction (LR) of the flexible line sections (4a, 4b), in that the connection device (4) has, with respect to the longitudinal direction (LR), a forward region (VB) and a rear region (HB), wherein the flexible line sections (4a, 4b) each have a forward section end (17, 18) in the forward region (VB) and a rear section end (19, 20) in the rear region (HB), in that the forward section end (17) of the first flexible line section (4a) and the rear section end (20) of the second flexible line section (4b) are rigidly connected to one another, in that the rear section end (19) of the first flexible line section (4a) and the forward section end (18) of the second flexible line section (4b) are rigidly connected to one another, and in that there is no continuous rigid connection between the control valve (3) and the cold head (2). The pulse tube cooler system suppresses both high-frequency vibrations of the control valve and low-frequency vibrations caused by pressure fluctuations in the connection device between the control valve and the cold head in a compact construction.
F25B 9/14 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point characterised by the cycle used, e.g. Stirling cycle
G01R 33/3815 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
G01R 33/38 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
A method for analyzing wine proposes puncturing the closure (60) of a wine bottle (61) containing wine (62) with a disposable cannula (3) having a lateral cannula opening (32) and a female Luer connection (30), and filling a disposable syringe (4) having a male Luer connection (41) with an inert gas. At least part (69) of the wine sample (65) is transferred into an analytical spectrometer (68) and spectrometric analysis of the wine sample (65) is carried out. An inexpensive method is thereby proposed that is easy to perform for analyzing a wine sample from a sealed wine bottle without impairing the quality or storage stability of the wine remaining in the wine bottle due to withdrawal of a wine sample from the wine bottle, in particular, wherein the volume of the removed wine sample can be easily controlled.
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
G01R 33/20 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance
NMR SPECTROMETER COMPRISING A SUPERCONDUCTING MAGNETIC COIL HAVING WINDINGS COMPOSED OF A SUPERCONDUCTOR STRUCTURE HAVING STRIP PIECES CHAINED TOGETHER
The invention relates to an NMR spectrometer (131), comprising an NMR magnetic coil (91), which comprises, at least in one section (121), windings having a conductor composed of a superconductor structure (1), comprising a plurality of strip pieces (2, 2a, 7a-7e, 8a-8d, 15) of strip-shaped superconductor, wherein each strip piece (2, 2a, 7a-7e, 8a-8d, 15) has a flexible substrate (3) and a superconducting layer (4) deposited on the flexible substrate, wherein the strip pieces (2, 2a, 7a-7e, 8a-8d, 15) each have a length of 20 m or more, and wherein the strip pieces (2, 2a, 7a-7e, 8a-8d, 15) are connected to each other, wherein at least one of the strip pieces (2, 2a, 7a-7e, 8a-8d, 15) is designed as a chained strip piece (2, 2a), and wherein each chained strip piece (2, 2a) is connected to at least two further strip pieces (7a-7e) in such a way that the further strip pieces (7a-7e) together overlap with at least 95% of the total length (L) of the chained strip piece (2, 2a). The invention provides an improved NMR spectrometer, in particular wherein a magnetic coil of the spectrometer can produce particularly high magnetic field strengths in a sample volume and has low drift.
G01R 33/3815 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
H01F 6/06 - Coils, e.g. winding, insulating, terminating or casing arrangements therefor
The invention relates to a magnetic coil assembly (1), comprising at least one coil section (2), which is wound with a high-temperature superconductor (HTS) strip conductor (4), and a low-temperature superconductor (LTS) wire (7), the HTS strip conductor (4) and the LTS wire (7) being electrically connected in series and the HTS strip conductor (4) and the LTS wire (7) forming a joint (6). The assembly is characterized in that a first end segment (19a) of the HTS strip conductor (4) before a first end (19) of the HTS strip conductor (4) and a first end segment (20a) of the LTS wire (7) before a first end (20) of the LTS wire (7) are connected to each other electrically, but not in a superconductive manner, in a connection segment (17) over the length of the connection segment (17), the LTS wire (7) being flat at least in the region of the connection segment (17) and the flat LTS wire (7) being laid against the HTS strip conductor (4) by means of one side of the flat LTS wire, and in that the connection segment (17) has a length of at least 5 m. The invention provides a magnetic coil assembly for which an acceptably small, residual ohmic resistance is established in a simple manner.
H01F 6/06 - Coils, e.g. winding, insulating, terminating or casing arrangements therefor
G01R 33/3815 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
21.
MICROWAVE COUPLER FOR OPTIMIZING A NMR PROBE HEAD FOR MAS-DNP
The invention relates to a NMR DNP-MAS probe head (10) comprising a MAS stator (2) for receiving a MAS rotor (3) having a sample substance in a sample volume (4), and a hollow microwave waveguide (5) for feeding microwave radiation through an opening (5a) of the microwave waveguide into the sample volume, an axially expanded rod-shaped microwave coupler (6) located in the opening made of dielectric material, characterized in that the microwave waveguide has a conically tapered hollow transition piece for coupling in an HE 11 mode, into which the microwave coupler projects at an all-round radial distance to the opening of the microwave waveguide. It is thus possible, in a surprisingly simple manner and by means of readily available technical means, to irradiate a considerably higher microwave energy in the HE 11 mode into the NMR measuring sample than by means of the known arrangements.
An NMR (nuclear magnetic resonance) sample head comprising a microwave resonator comprising at least two elements which are reflective in the microwave range, at least one of which is focusing, wherein the reflective elements at least partly delimit a resonance volume of the microwave resonator, is characterized in that at least one of the reflective elements is embodied as a DBR ("Distributed Bragg Reflector"), and in that the NMR sample head comprises at least one NMR coil integrated into the DBR. Thus, an NMR detection coil can be positioned particularly near to the sample and the distortions of the static field by resonator components are reduced, such that the detection sensitivity and the spectral resolution of the experiment are significantly improved.
G01R 33/28 - Details of apparatus provided for in groups
G01R 33/62 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
G01R 33/345 - Constructional details, e.g. resonators of waveguide type
G01N 24/12 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using double resonance
An NMR experiment on hyperpolarizable magnetic nuclei of substrate molecules in a living human or animal body, involves polarizing the substrate molecules by non-hydrogenating para-hydrogen induced polarization (=NH-PHIP) into a singlet/pseudo singlet state in low magnetic field and injecting the substrate molecules into the living body, the body or a part thereof being previously located inside a magnet at low magnetic field. The magnet is switched on to high magnetic field, and in at least part of the substrate molecules, the singlet state/pseudo singlet state is converted into observable magnetization. An MRI or MRS measurement is carried out with the living body or the part thereof, collecting data from the substrate molecules. The NMR experiment is well applicable on hyperpolarized nuclei within a patient, with reduced losses of magnetization due to relaxation processes.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
G01V 3/00 - Electric or magnetic prospecting or detectingMeasuring magnetic field characteristics of the earth, e.g. declination or deviation
24.
NMR measurement apparatus with flow-through probehead
b) the gas pressure, and in which at least one chamber (4, 22, 32) comprises means for mixing the liquid measurement sample (10) contained in the chamber (4, 22, 32) with a gas With the inventive device it is possible to reduce the measurement sample consumption when doing an NMR spectroscopic measurement on liquid measurement samples to which spin order can be catalytically transferred.
The invention relates to a rotary valve (1) for a cryocooler, in particular for a pulse tube cooler or for a Gifford-McMahon cooler, comprising a rotary body (6) that can be rotated by a motor about a rotary axis (DA), a control plate (5), and an axial rolling bearing, by means of which the rotary body (6) can roll along the control plate (5), characterized in that the axial roller bearing is designed as a bearing (19a-19c) that is non-centering in the radial direction (RR). The invention relates to a rotary valve for a cryocooler, having low wear and thereby being simple to produce and assemble.
F16K 11/074 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members with flat sealing faces
F16K 31/04 - Operating meansReleasing devices electricOperating meansReleasing devices magnetic using a motor
26.
NMR MEASUREMENT APPARATUS WITH FLOW-THROUGH PROBEHEAD
The invention relates to a device (1, 21, 31, 41, 64) for the preparation and measurement of a nuclear spin resonance (NMR) measurement sample (10), including - a flow-through NMR probehead (2), with a first tube (3) and a second tube (14) each for the supply and removal of a liquid NMR measurement sample (10), - at least one chamber (4, 22, 32) which is connected to one of the tubes (3, 14), - a sample inlet (5) for introducing the liquid measurement sample (10) into the device (1, 21, 31, 41, 64), wherein at least one chamber (4, 22, 32) has at least one connection for increasing (9, 24, 25, 42, 43, 46, 47) and releasing (8, 23, 27, 48a, 48b) the gas pressure, and in which at least one chamber (4, 22, 32) comprises means for mixing the liquid measurement sample (10) contained in the chamber (4, 22, 32) with a gas With the inventive device it is possible to reduce the measurement sample consumption when doing an NMR spectroscopic measurement on liquid measurement samples to which spin order can be catalytically transferred.
L<4 K. The apparatus is characterized in that the HTS section (4) is disposed radially within the LTS section (5, 6) in a separate helium tank (19) of the cryostat (1) having normal liquid helium and is separated from the LTS section (5, 6) by means of at least one wall disposed between the two helium tanks. An HTS coil section can be maintained in the cryostat in accordance with the invention over a long period of time and in a reliable fashion.
L is gaseous. The cryostat in accordance with the invention can be utilized to maintain HTS coil sections over a long period of time in a reliable fashion.
0 by means of magnetic resonance is disclosed. It comprises a resonator portion defining a longitudinal axis and an axial direction. The resonator portion has, along the axial direction, a hollow cavity for exciting electron resonance within the sample. A coupling portion is provided adjacent the resonator portion and has, along the longitudinal axis, a stepped through being electrically conductive at its inner surface. A first, middle section of the stepped through configures the hollow cavity. A second and a third, lateral section adjacent axially opposed sides of the hollow cavity are each dimensioned such that a basic mode being resonant within the hollow cavity is unable to propagate within the second and the third section. A coil is wound around the resonator portion for additionally exciting a nuclear resonance within the sample. The resonator portion comprises a toroidal body made from an electrically conductive material within which there is provided the stepped through. The toroidal body is provided with at least one axial slit.
A method for measuring the magnetic resonance of sample molecules (1) soluble in a polar solvent, electromagnetic high-frequency (=HF) field acting on the sample molecules (1), characterized in that the sample molecules (1) are present in a measuring emulsion (4) during measurement, wherein in the measuring emulsion (4) the sample molecules (1) are enclosed in molecular receptacles, in particular inverse micelles (2), and the molecular receptacles are distributed in a homopolar solvent (3). The invention enables the measurement of the magnetic resonance of water-soluble sample material with low apparatus-related complexity at a good signal-to-noise ratio, even at high frequencies of the irradiated HF fields.
A method is described for determining a characteristic, such as the mass, of each of a plurality of samples. The method comprises the steps of providing a plurality of coil elements each for surrounding a respective sample, causing the samples to enter an interrogation zone, each sample being surrounded by a respective coil element when it is located within the interrogation zone, applying a magnetic field in a first direction in the interrogation zone for creating in a pre-polarised state a net nuclear magnetisation of a nuclear spin species within a sample located in the interrogation zone, applying, by each coil element surrounding a respective sample located in the interrogation zone, an RF field in a second direction for temporarily changing the net nuclear magnetisation of the nuclear spin species in the sample, detecting RF energy emitted from that sample as the net nuclear magnetisation of the nuclear spin species in the sample relaxes, and, from the detected RF energy, determining the characteristic of each sample located in the interrogation zone.
A cryostat (1) having a magnet coil system, which comprises superconductive conductors, for producing a magnetic field BO in a measurement volume (3) in a room temperature drilled hole (2) of the cryostat (1), having a plurality of solenoid-like coil sections (4, 5, 6), which are arranged nested radially one inside the other, surround the room temperature drilled hole and are connected electrically in series and of which at least one LTS section (5, 6) comprises a conventional low-temperature superconductor (LTS) and at least one HTS section (4) comprises a high-temperature superconductor (HTS), wherein the LTS section (5, 6) is located with liquid helium in a helium tank (9) of the cryostat (1) at a helium temperature TL, is characterized by the fact that the HTS section (4) is arranged radially within the LTS section (5, 6) in a vacuum part (14) of the cryostat (1) and is separated from the LTS section (5, 6) by the wall (9a) of the helium tank (9) which faces the room temperature drilled hole (2). The HTS coil section can be used in the long term and reliably in the cryostat.
A cryostat (1) having a magnet coil system, which comprises superconductive conductors, for producing a magnetic field B0 in a measurement volume (3), having a plurality of solenoid-like coil sections (4, 5, 6), which are arranged nested radially one inside the other and are connected electrically in series and of which at least one LTS section (5, 6) comprises a conventional low-temperature superconductor (LTS) and at least one HTS section (4) comprises a high-temperature superconductor (HTS), wherein the LTS section is located with liquid helium in a first helium tank (9) of the cryostat (1) at a helium temperature TL < 4 K, is characterized by the fact that the HTS section (4) is arranged radially within the LTS section (5, 6) in a separate helium tank (19) of the cryostat (1) with standard liquid helium and is separated from the LTS section (5, 6) by at least one wall between the two helium tanks. An HTS coil section can be used in the long term and reliably in the cryostat according to the invention.
A cryostat (1) having a magnet coil system, which comprises superconductive conductors, for producing a magnetic field B0 in a measurement volume (3), having a plurality of solenoid-like coil sections (4, 5, 6), which are arranged nested radially one inside the other and are connected electrically in series and of which at least one LTS section (5, 6) comprises a conventional low-temperature superconductor (LTS) and at least one HTS section (4) comprises a high-temperature superconductor (HTS), wherein the magnet coil system is located with liquid helium in a helium tank (9) of the cryostat (1) at a helium temperature TL < 4 K, is characterized by the fact that heating means are provided which keep the HTS at any time at an elevated temperature TH > TL and TH > 2.2 K. The HTS section can be used in the long term and reliably in the cryostat according to the invention.
A cryostat (1) having a magnet coil system, which comprises superconductive conductors, for producing a magnetic field Bo in a measurement volume (3), having a plurality of solenoid-like coil sections (4, 5, 6), which are arranged nested radially one inside the other and are connected electrically in series and of which at least one LTS section (5, 6) comprises a conventional low-temperature superconductor (LTS) and at least one HTS section (4) comprises a high-temperature superconductor (HTS), wherein the magnet coil system is located with liquid helium in a helium tank (9) of the cryostat (1) at a helium temperature TL, is characterized by the fact that a chamber (11) is provided around the HTS section(s) (4), a pressure prevailing in the interior of said chamber which is so low that helium present there remains gaseous at the temperature TL. An HTS coil section can be used in the long term and reliably in the cryostat according to the invention.
H01F 6/06 - Coils, e.g. winding, insulating, terminating or casing arrangements therefor
G01R 33/3815 - Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
The invention relates to a method for the acquisition of data relating to multi-dimensional NMR spectra, whereby according to a method known as the SHARC protocol (SHaped ARrayed data aCquisition Protocol), crossed signals are randomly shifted in the frequency range by means of selective pulses and frequency-dependent convolution.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Analytical instruments, in particular magnetic resonance spectrometers, including NMR and ESR spectrometers, magnetic resonance tomographs, precision magnets, including high-field magnets, namely, permanent magnets and electromagnets, superconducting magnet devices, optical spectrometers, X-ray spectrometers and diffractometers, mass spectrometers, gas analyzers; electrical power supplies; electronic instruments for processing and displaying of measured values provided by spectrometers or tomographs; data processing equipment and computers; cryostats. (1) Service for spectrometers; performing spectrometric measurements; computer programming, in particular for analytical instruments.
09 - Scientific and electric apparatus and instruments
Goods & Services
materials testing device, namely, nanosecond pulse programmers for use with electron paramagnetic resonance (EPR) spectrometers for pulsed electron paramagnetic resonance experiments on samples
09 - Scientific and electric apparatus and instruments
Goods & Services
MEDICAL MEASURING INSTRUMENTS, NAMELY SPECTROMETERS AND ELECTRONIC DATA PROCESSING INSTRUMENTS TO BE USED IN CONNCETION WITH SAID SPECTROMETERS AND PARTS OF THE AFOREMENTIONED GOODS
