Nucleic Acid Strand Cleaving Method, Nucleic Acid Strand Cleaving Device, Double-Stranded DNA Production Method, and Double-Stranded DNA Production Device
There is provided a nucleic acid strand cleaving method including a nucleic acid preparation step of preparing a nucleic acid to be cleaved having a structure represented by the following Formula (1), and a cleaving step of reacting the nucleic acid to be cleaved with a cleaving agent to cleave the nucleic acid to be cleaved at the part X of the Formula (1) to generate a nucleic acid having a structure represented by the following Formula (2). The cleaving agent is a metal nanoparticle containing an atom selected from the group consisting of silver, mercury, and cadmium. [Chemical Formula 1] Here, B represents a base, and X represents sulfur or selenium. NucA is composed of at least one nucleotide and is a part of the nucleic acid to be cleaved, and represents a part on the 5′ end side with reference to the X. NucB is composed of at least one nucleotide and is a part of the nucleic acid to be cleaved, and represents a part on the 3′ end side with reference to the X.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
2.
ZWITTERION-CONTAINING COMPOSITION, AND USE THEREOF
The present invention addresses the problem of providing a composition with which it becomes possible to improve the recovery rate of spheroids after storage by minimizing the damage to the spheroids under non-cryopreservation. The present invention relates to a composition for non-cryopreservation of a multicell cluster, the composition containing one or more types of aprotic zwitterionic compounds (A) and two or more types of additives (X) that are compatible with the components (A).
A droplet control device for controlling droplets produced from a polysaccharide and a polyether, the droplet control device comprising: a light irradiation unit for irradiating light; and a monitoring unit for monitoring the state of the droplets. An aqueous medium including the droplets further includes a photoisomerizable compound. The light irradiation unit irradiates the aqueous medium with light of a wavelength that photoisomerizes the photoisomerizable compound.
C12M 1/00 - Apparatus for enzymology or microbiology
C12M 1/36 - Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
G01N 37/00 - Details not covered by any other group of this subclass
This polymer compound has a structure in which a conjugated carbon atom of a condensed polycyclic aromatic ring group and a silicon atom are bonded to each other in a bond-cleavable form by cooperative action between light irradiation and an acid.
A bistable circuit includes a pair of inverter circuits each including a first FET being connected between a power supply line and an intermediate node and having a gate coupled to an input node and a first conductivity type channel, a second FET being connected between the intermediate node and an output node and having a gate coupled to the input node and the first conductivity type channel, a third FET being connected between the intermediate node and a bias node, a fourth FET being connected between the output node and a control line and having a gate coupled to a word line and a second conductivity type channel, wherein the pair of inverter circuits are connected in a loop shape, and gates of the third FETs of the pair of inverter circuits are coupled to one of the input and output nodes of the pair of inverter circuits.
G11C 11/412 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using electric elements using semiconductor devices using transistors forming cells with positive feedback, i.e. cells not needing refreshing or charge regeneration, e.g. bistable multivibrator or Schmitt trigger using field-effect transistors only
H03K 3/3565 - Bistables with hysteresis, e.g. Schmitt trigger
H10B 10/00 - Static random access memory [SRAM] devices
6.
FIELD EFFECT TRANSISTOR, INTEGRATED CIRCUIT, ELECTRONIC DEVICE, METHOD FOR SWITCHING POLARITY OF FIELD EFFECT TRANSISTOR, AND METHOD FOR CHANGING INTEGRATED CIRCUIT
A field effect transistor according to the present invention includes: a semiconductor substrate composed of a single crystal semiconductor having a resistivity of 0.01 kΩ cm or more at an arbitrary temperature or an impurity concentration of 1×1016/cm3 or less; a gate insulating layer in contact with the semiconductor substrate; a control gate electrode in contact with the gate insulating layer; one or a plurality of storage gate electrodes in contact with the gate insulating layer and arranged side by side with the control gate electrode; and a terminal electrode in contact with the semiconductor substrate.
H01L 29/78 - Field-effect transistors with field effect produced by an insulated gate
H01L 21/82 - Manufacture or treatment of devices consisting of a plurality of solid state components or integrated circuits formed in, or on, a common substrate with subsequent division of the substrate into plural individual devices to produce devices, e.g. integrated circuits, each consisting of a plurality of components
H01L 21/8238 - Complementary field-effect transistors, e.g. CMOS
H01L 27/092 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being a semiconductor body including only semiconductor components of a single kind including field-effect components only the components being field-effect transistors with insulated gate complementary MIS field-effect transistors
A quantum device 10 includes: a data quantum bit 11; a readout resonator 12 coupled to the data quantum bit 11; a readout waveguide 13 coupled to the readout resonator 12; and a nonlinear filter 14 interposed between the readout resonator 12 and the readout waveguide 13. The nonlinear filter 14 has different transmission characteristics depending on the amplitude of a readout pulse input to the readout waveguide 13.
This unicellular algae contains at least 0.1 mass% saccharides; are capable of growing in a culture medium under acidic conditions of a pH 5 or lower; and have a chlorophyll content of at least 1 μg/mg dry weight after 7 days of culture under dark conditions in the presence of an organic carbon source.
An electronic circuit includes a cell array including memory cells each including a bistable circuit that includes first and second inverter circuits, each having a first mode characterized by there being substantially no hysteresis in transfer characteristics and a second mode characterized by there being hysteresis in the transfer characteristics, and being switchable between the first and second modes, and a control circuit configured to, after powering off a first memory cell that store data that are not required to be retained, put the bistable circuit in a remaining second memory cell into the second mode, and supply a second power supply voltage that allows the bistable circuit in the second mode to retain data and is lower than a first power supply voltage supplied to the bistable circuit when data is read and/or written, to the bistable circuit in the second memory cell while maintaining the second mode.
G11C 11/412 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using electric elements using semiconductor devices using transistors forming cells with positive feedback, i.e. cells not needing refreshing or charge regeneration, e.g. bistable multivibrator or Schmitt trigger using field-effect transistors only
G11C 11/56 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using storage elements with more than two stable states represented by steps, e.g. of voltage, current, phase, frequency
G11C 14/00 - Digital stores characterised by arrangements of cells having volatile and non-volatile storage properties for back-up when the power is down
2–x2–x (In general formula (1), A is at least one type of element selected from the group consisting of Si, Fe, Ni, Mo, and Zr, and x represents a numerical value represented by 0≤x<2.0.)
3-x3-xyy (A is at least one member selected from the group consisting of Ba and Sr, x is a number represented by 0.1≤x≤2.0, and y is a number represented by 0.1≤y≤1.0.)
C01B 3/04 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of inorganic compounds, e.g. ammonia
B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
A sign detection device 1 comprises: an acquisition unit 10 that acquires space-time data of a multidimensional variable indicating a state of a target; a prediction error analysis unit 20 that estimates a deviation between a prediction value and an actual measurement value of time data in the space-time data; a fluctuation analysis unit 30 that estimates fluctuation of the space-time data; and a sign detection unit 40. The prediction error analysis unit 20 calculates the prediction value by converting the space-time data of the multidimensional variable into time data of a target variable which is a variable to be predicted by the sign detection device 1, and estimates the deviation between the prediction value and the actual measurement value. The fluctuation analysis unit 30 calculates fluctuation of the state of the target by means of fluctuation analysis using the space-time data. When the deviation estimated by the prediction error analysis unit 20 exceeds a predetermined first threshold value and the fluctuation estimated by the fluctuation analysis unit exceeds a predetermined second threshold value, the sign detection unit 40 detects that there is a sign of a state transition in the target.
G06Q 10/04 - Forecasting or optimisation specially adapted for administrative or management purposes, e.g. linear programming or "cutting stock problem"
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
This fault-tolerant quantum error correction device comprises: a quantum circuit that includes a plurality of physical quantum bits; an encoding unit that encodes the physical quantum bits to generate logical quantum bits; and an error correction unit that performs error correction using the logical quantum bits of a quantum error correction code. The quantum error correction code is a concatenated code obtained by concatenating a plurality of quantum codes. As the size of the concatenated code increases, the ratio between the size of the logical quantum bits forming the concatenated code and the size of the physical quantum bits approaches a finite value.
H03M 13/29 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes combining two or more codes or code structures, e.g. product codes, generalised product codes, concatenated codes, inner and outer codes
G06N 10/70 - Quantum error correction, detection or prevention, e.g. surface codes or magic state distillation
14.
LOGICAL OPERATION ELEMENT, LOGIC DEVICE, NOT LOGIC DEVICE, SWITCHABLE NOT LOGIC DEVICE, XOR LOGIC DEVICE, AND LOGIC DEVICE, OR LOGIC DEVICE, AND HALF ADDER
A logical operation element 1A includes: a one-dimensional thin line structure 10 in which an electron spin wave propagates; and a gate electrode 20A along a part of the one-dimensional thin line structure 10. A logic input to the logical operation element 1A is a phase state of the electron spin wave before propagating through the one-dimensional thin line structure 10. A logic output of the logical operation element 1A is a phase state of the electron spin wave after propagating through the one-dimensional thin line structure 10.
H03K 19/18 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits using specified components using galvano-magnetic devices, e.g. Hall-effect devices
POLYPEPTIDE DERIVED FROM ANTIBODY LIGHT-CHAIN HAVING HER2 DECOMPOSITION ACTIVITY, HER2-BINDING POLYPEPTIDE COMPRISING SAID POLYPEPTIDE, METHODS FOR PRODUCING SAID POLYPEPTIDES, AND USE OF SAID POLYPEPTIDES
The present invention provides a super antibody enzyme that comprises an antibody having a high anti-cancer effect and imparted with a high enzymatic activity. The present invention relates to a polypeptide in which hypervariable regions are derived from an anti-HER2 antibody light-chain, such as those mentioned in (1a) below. (1a) A polypeptide comprising an amino acid sequence that includes a CDR1 region comprising the amino acid sequence represented by SEQ ID NO:1, a CDR2 region comprising the amino acid sequence represented by SEQ ID NO:2 and a CDR3 region comprising the amino acid sequence represented by SEQ ID NO:3, and has a 70th aspartic acid residue in a variable region in accordance with the Kabat numbering scheme, wherein 95th and 96th proline residues in a variable region in accordance with the Kabat numbering scheme are deleted or are substituted by amino acid residues other than proline residues.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
A silicon bulk thermoelectric conversion material having improved thermoelectric performance compared to conventional material is provided. Alternatively, a method for manufacturing a silicon bulk thermoelectric conversion material having improved thermoelectric performance by reducing thermal conductivity compared to the conventional method is provided. A silicon bulk thermoelectric conversion material according to an embodiment of the present invention includes a housing step of putting a silicon powder containing silicon nanoparticles between a first electrode member and a second electrode member of a heating unit, a heating step of heating the silicon powder by applying current while applying pressure equal to or less than 12 MPa between the first electrode member and the second electrode member and a cooling step of cooling the heated silicon powder.
A storage device according to the present invention is provided with: a semiconductor layer; a gate electrode that faces the semiconductor layer; an insulating layer that is provided between the semiconductor layer and the gate electrode; and a ferroelectric layer that is provided between the insulating layer and the gate electrode, and contains hafnium oxide. In this storage device, the film thickness of the ferroelectric layer is larger than 3 nm but smaller than 7 nm. Alternatively, a storage device according to the present invention is provided with: an oxide semiconductor layer; a gate electrode that faces the oxide semiconductor layer; and a ferroelectric layer that is provided between the oxide semiconductor layer and the gate electrode, and contains hafnium oxide. In this storage device, the film thickness of the ferroelectric layer is larger than 3 nm but smaller than 30 nm.
Provided is a catalyst composition that has sufficient reaction activity even under low-temperature low-pressure conditions. The catalyst composition according to the present embodiment contains a perovskite-type acid hydride represented by a predetermined formula.
B01J 23/63 - Platinum group metals with rare earths or actinides
B01J 23/83 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with rare earths or actinides
A data processing device to estimate the limit:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
[
equation
75
]
z
(
t
)
∈
R
n
expressed as:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
[
equation
75
]
z
(
t
)
∈
R
n
expressed as:
(
13
)
z
˙
(
t
)
=
A
⊤
z
(
t
)
[
equation
74
]
calculates:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
[
equation
75
]
z
(
t
)
∈
R
n
expressed as:
(
13
)
z
˙
(
t
)
=
A
⊤
z
(
t
)
[
equation
74
]
calculates:
(
16
)
z
⊤
(
t
2
)
Xz
(
t
2
)
-
z
⊤
(
t
1
)
Xz
(
t
1
)
=
-
∫
t
1
t
2
z
⊤
(
t
)
BB
T
z
(
t
)
dt
[
equation
81
]
z
(
t
+
t
i
1
,
t
i
1
,
x
i
1
)
=
(
E
(
t
)
E
0
-
1
)
⊤
x
i
1
[
equation
89
]
and estimates:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
[
equation
75
]
z
(
t
)
∈
R
n
expressed as:
(
13
)
z
˙
(
t
)
=
A
⊤
z
(
t
)
[
equation
74
]
calculates:
(
16
)
z
⊤
(
t
2
)
Xz
(
t
2
)
-
z
⊤
(
t
1
)
Xz
(
t
1
)
=
-
∫
t
1
t
2
z
⊤
(
t
)
BB
T
z
(
t
)
dt
[
equation
81
]
z
(
t
+
t
i
1
,
t
i
1
,
x
i
1
)
=
(
E
(
t
)
E
0
-
1
)
⊤
x
i
1
[
equation
89
]
and estimates:
G
(
∞
)
=
X
[
equation
146
]
by numerically obtaining the solution X of the following linear equation:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
[
equation
75
]
z
(
t
)
∈
R
n
expressed as:
(
13
)
z
˙
(
t
)
=
A
⊤
z
(
t
)
[
equation
74
]
calculates:
(
16
)
z
⊤
(
t
2
)
Xz
(
t
2
)
-
z
⊤
(
t
1
)
Xz
(
t
1
)
=
-
∫
t
1
t
2
z
⊤
(
t
)
BB
T
z
(
t
)
dt
[
equation
81
]
z
(
t
+
t
i
1
,
t
i
1
,
x
i
1
)
=
(
E
(
t
)
E
0
-
1
)
⊤
x
i
1
[
equation
89
]
and estimates:
G
(
∞
)
=
X
[
equation
146
]
by numerically obtaining the solution X of the following linear equation:
[
Equation
6
]
x
i
1
⊤
(
E
(
h
)
E
0
-
1
)
X
(
E
(
h
)
E
0
-
1
)
⊤
x
i
1
-
x
i
1
⊤
Xx
i
1
=
-
∫
0
h
x
i
1
⊤
(
E
(
t
)
E
0
-
1
)
BB
⊤
(
E
(
t
)
E
0
-
1
)
⊤
x
i
1
dt
(
i
=
1
,
2
,
…
,
q
)
with respect to:
A data processing device to estimate the limit:
G
(
∞
)
[
equation
140
]
of a controllability Gramian:
G
(
t
)
[
equation
138
]
defined by:
G
(
t
)
:
=
∫
0
t
c
A
τ
BB
⊤
e
A
⊤
τ
d
τ
[
equation
2
]
in:
t
=
∞
[
equation
144
]
when:
x
˙
(
t
)
=
Ax
(
t
)
+
Bu
(
t
)
[
equation
1
]
holds, where:
x
(
t
)
[
equation
142
]
is an n-dimensional vector representing the state of a control object:
u
(
t
)
[
equation
139
]
is an m-dimensional vector representing the control input, A is an unknown n×n matrix and B is a known n×m matrix, comprises:
a data acquisition unit that acquires a set of time-series state data:
x
(
[
t
11
,
t
1
2
]
,
x
1
1
)
,
x
(
[
t
2
1
,
t
2
2
]
,
x
1
1
)
,
…
,
x
(
[
t
q
1
,
t
q
2
]
,
x
q
1
)
[
equation
5
]
for the following q time intervals:
[
t
i
1
,
t
i
2
]
[
equation
4
]
(
i
=
1
,
2
,
…
,
q
)
when:
u
(
t
)
≡
0
[
equation
39
]
holds;
a controllability Gramian calculation unit that defines:
[
equation
75
]
z
(
t
)
∈
R
n
expressed as:
(
13
)
z
˙
(
t
)
=
A
⊤
z
(
t
)
[
equation
74
]
calculates:
(
16
)
z
⊤
(
t
2
)
Xz
(
t
2
)
-
z
⊤
(
t
1
)
Xz
(
t
1
)
=
-
∫
t
1
t
2
z
⊤
(
t
)
BB
T
z
(
t
)
dt
[
equation
81
]
z
(
t
+
t
i
1
,
t
i
1
,
x
i
1
)
=
(
E
(
t
)
E
0
-
1
)
⊤
x
i
1
[
equation
89
]
and estimates:
G
(
∞
)
=
X
[
equation
146
]
by numerically obtaining the solution X of the following linear equation:
[
Equation
6
]
x
i
1
⊤
(
E
(
h
)
E
0
-
1
)
X
(
E
(
h
)
E
0
-
1
)
⊤
x
i
1
-
x
i
1
⊤
Xx
i
1
=
-
∫
0
h
x
i
1
⊤
(
E
(
t
)
E
0
-
1
)
BB
⊤
(
E
(
t
)
E
0
-
1
)
⊤
x
i
1
dt
(
i
=
1
,
2
,
…
,
q
)
with respect to:
[
equation
157
]
E
(
t
)
:=
[
x
(
?
+
?
,
?
,
x
11
x
(
?
+
?
,
?
,
x
21
)
…
x
(
t
+
t
n
1
,
t
n
1
,
x
n
1
)
]
[
equation
158
]
E
0
:=
[
x
11
x
21
…
x
n
1
]
;
?
indicates text missing or illegible when filed
and
an output unit that outputs the input matrix when the controllability Gramian is maximized based on the estimated maximization condition.
The present disclosure is a structure for nucleic acid delivery to be used for the treatment of hematopoietic tumors, the structure being characterized by having an association structure in which a nucleic acid analog represented by formula (1) and a nucleic acid to be delivered comprising a microRNA that controls a network of cancer genes KRAS are associated by electrostatic interaction. (Here, N represents a cationic artificial nucleic acid, H represents a hydrophilic polymer, S1 represents a spacer 1, S2 represents a spacer 2, and L represents a ligand; N has a constituent unit in which a base is bonded to a hexose selected from ribose and deoxyribose, a connection structure connecting two constituent units, and a backbone structure composed of cationic groups; and the cationic artificial nucleic acid can be associated by electrostatic interaction between a phosphate group of the nucleic acid to be delivered and the cationic groups.)
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
A61K 31/7125 - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
A quantum computation controller according to one embodiment has a control signal generator, an observation unit that receives an observation signal indicating the state of each qubit and a qubit module. The qubit module has a qubit substrate on which a plurality of qubits are arranged, a control circuit, an observation circuit, and a signal processing circuit. The qubits are grouped into a plurality of groups. The control signal generator generates a control signal for performing a first operation, a control signal for performing a second operation and an instruction signal. The control circuit splits the control signal into groups and controls the sending of the control signal. The observation circuit observes the state of each qubit on which the first operation or the second operation has been performed. The signal processing circuit sends the observation signal of each qubit to the observation circuit.
Disclosed herein is an electrochemical cell and a production system for selectively reducing, using electrical energy, CO2 to carbon monoxide or formic acid, a catalyst for use in the method, and an electrochemical reduction system. The method for producing carbon monoxide or formic acid by electrochemically reducing carbon dioxide of the present invention includes (a) reacting carbon dioxide with a metal complex represented by formula (1), and (b) applying a voltage to a reaction product of the carbon dioxide and the metal complex represented by formula (1):
Disclosed herein is an electrochemical cell and a production system for selectively reducing, using electrical energy, CO2 to carbon monoxide or formic acid, a catalyst for use in the method, and an electrochemical reduction system. The method for producing carbon monoxide or formic acid by electrochemically reducing carbon dioxide of the present invention includes (a) reacting carbon dioxide with a metal complex represented by formula (1), and (b) applying a voltage to a reaction product of the carbon dioxide and the metal complex represented by formula (1):
The composite fine particle includes an inorganic fine particle having a light wavelength conversion ability, a continuous or discontinuous first coating layer formed on the whole or a part of a surface of the inorganic fine particle, a second coating layer formed on the first coating layer, and a third coating layer formed on the second coating layer, in which the second coating layer contains a multidentate organic ligand that is an organic compound having light absorption in a near-infrared or infrared range and has at least two or more coordination sites, and the first coating layer is a metal layer or an inorganic compound layer containing a coordination metal and a transition metal identical to or different from the coordination metal, and the third coating layer is a metal layer or an inorganic compound layer containing a coordination metal.
C09K 11/02 - Use of particular materials as binders, particle coatings or suspension media therefor
H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
24.
Method for Producing Compound, Compound, and Metal Catalyst
One aspect of the present invention is a method for producing a compound represented by following general formula (1), the method being characterized by including a step of mixing ethylene, a compound represented by following general formula (2), and a compound represented by following general formula (3) to react with each other to give a compound represented by following general formula (4):
One aspect of the present invention is a method for producing a compound represented by following general formula (1), the method being characterized by including a step of mixing ethylene, a compound represented by following general formula (2), and a compound represented by following general formula (3) to react with each other to give a compound represented by following general formula (4):
A1 to A4 each independently represent an aromatic group, and Z1 and Z2 each independently represent an oxygen atom, a sulfur atom, or a borane (BH3), Z3 represents an oxygen atom or a sulfur atom, n1 to n3 each independently represent 0 or 1, and X represents a halogen atom.
A measurement device 100 comprises: a sound wave generation source 10 for irradiating sound waves at each of different sections to be measured in a prescribed region; and a measurement unit 20 for receiving an electromagnetic field generated at each section to be measured irradiated with the sound waves, and measuring a signal indicating at least one characteristic selected from the group consisting of electric characteristics, magnetic characteristics, electromechanical characteristics, and magnetic mechanical characteristics to be measured on the basis of at least one selected from the group consisting of the intensity, phase, and frequency of the received electromagnetic field. The times at which the sound waves generated by the sound wave generation source reach different sections to be measured in the prescribed region are equal.
National University Corporatjion Tokai National Higher Education and Research System (Japan)
Inventor
Abe, Hiroshi
Abe, Naoko
Inagaki, Masahito
Kimura, Yasuaki
Hashiya, Fumitaka
Li, Zhenmin
Nakashima, Yuko
Abstract
A method for purifying a nucleotide-based substance; including a protecting group introduction step of introducing a hydrophobic protecting group represented by the following formula (P1) or (P2) into a nucleotide-based substance to produce a hydrophobic nucleotide-based substance; an isolation and purification step of isolating and purifying the hydrophobic nucleotide-based substance under a hydrophobic environment; and a deprotection step of deprotecting the hydrophobic protecting group from the hydrophobic nucleotide-based substance to produce the nucleotide-based substance,
A method for purifying a nucleotide-based substance; including a protecting group introduction step of introducing a hydrophobic protecting group represented by the following formula (P1) or (P2) into a nucleotide-based substance to produce a hydrophobic nucleotide-based substance; an isolation and purification step of isolating and purifying the hydrophobic nucleotide-based substance under a hydrophobic environment; and a deprotection step of deprotecting the hydrophobic protecting group from the hydrophobic nucleotide-based substance to produce the nucleotide-based substance,
wherein R1 represents a linear or branched alkyl group having 1 to 30 carbon atoms, R4 represents hydrogen or a linear or branched alkyl group having 1 to 10 carbon atoms, R2, R3, R5 and R6 represent hydrogen, a linear or branched alkyl group having 1 to 10 carbon atoms, or the like, and may be the same or different; and * means a bond with a nucleotide-based substance.
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
C07H 17/02 - Heterocyclic radicals containing only nitrogen as ring hetero atoms
C07H 21/00 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
27.
CORE-SHELL TYPE UPCONVERTING MICROPARTICLE, UPCONVERTING MICRO PRECURSOR PARTICLE, SENSITIZING CORE-SHELL TYPE UPCONVERTING MICROPARTICLE, TIO2-COATED CORE-SHELL TYPE UPCONVERTING MICROPARTICLE, NEAR-INFRARED DETECTOR, PHOTOELECTRIC CONVERSION ELEMENT, AND METHOD FOR PRODUCING CORE-SHELL TYPE UPCONVERTING MICROPARTICLE
This core-shell type upconverting microparticle is an upconverting particle comprising a core section and a shell section covering the core section. The core-shell type upconverting microparticle has a hexagonal columnar particle shape, a particle diameter of 300 nm or more, a thickness of 100 nm or more, and an aspect ratio, defined as the particle diameter/particle thickness, of at least 1.2 and not more than 5.0.
C01F 17/36 - Compounds containing rare earth metals and at least one element other than a rare earth metal, oxygen or hydrogen, e.g. La4S3Br6 halogen being the only anion, e.g. NaYF4
H01L 31/055 - Optical elements directly associated or integrated with the PV cell, e.g. light-reflecting means or light-concentrating means where light is absorbed and re-emitted at a different wavelength by the optical element directly associated or integrated with the PV cell, e.g. by using luminescent material, fluorescent concentrators or up-conversion arrangements
H10K 30/15 - Sensitised wide-bandgap semiconductor devices, e.g. dye-sensitised TiO2
H10K 30/60 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation in which radiation controls flow of current through the devices, e.g. photoresistors
To provide a novel photothermal conversion material. This manganese oxide cluster compound is represented by general formula (1). (In general formula (1), L is a tricarboxytriptycene residue, α1is an organic acid residue, β1is a solvent selected from water and a polar organic solvent having a dielectric constant of 6-47, P1is a coordinating molecule selected from a nitrogen-containing heterocyclic compound, an oxygen-containing cyclic compound, and a phosphine, or a polymer containing the coordinating molecule, γ1 is a solvent selected from water and a polar organic solvent having a dielectric constant of 6-47, q is a number satisfying 0≤m≤8, and m is a number satisfying 0≤m≤10.)
This air battery is provided with a positive electrode, a negative electrode containing an alkali metal ion, and an electrolyte containing an alkali metal salt, wherein both the alkali metal ion and the alkali metal constituting the alkali metal salt are rubidium or cesium.
The problem to be solved by the present invention is to provide novel organic nanoparticles and a novel compound for constituting the organic nanoparticles. The present invention provides a compound represented by the following formula (1) or a salt thereof:
The problem to be solved by the present invention is to provide novel organic nanoparticles and a novel compound for constituting the organic nanoparticles. The present invention provides a compound represented by the following formula (1) or a salt thereof:
The problem to be solved by the present invention is to provide novel organic nanoparticles and a novel compound for constituting the organic nanoparticles. The present invention provides a compound represented by the following formula (1) or a salt thereof:
wherein R1s are the same or different and each represent hydrogen, a hydroxy group, or a carbon-containing organic group; and R2s are the same or different and each represent an optionally substituted ethylene group or trimethylene group.
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
A61K 31/4745 - QuinolinesIsoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
The present disclosure is lipid nanoparticles composed of a composition containing a protein selected from among an antibody and an antibody fragment, a polymer, and a lipid, and characterized in that the polymer and the protein have opposite electric charges at a predetermined pH. In the lipid nanoparticles, the protein is preferably encapsulated. Moreover, the peak top in the particle diameter distribution is preferably 80-120 nm when measuring the particle diameters of the lipid nanoparticles.
A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
A spiking neuron circuit system includes: a charging circuit that, when an input voltage is applied, starts charging of a capacitor by an output current of a field effect transistor; a pulse generation circuit that generates and outputs a pulse signal when a charged voltage of the capacitor reaches a first predetermined value; and a control circuit that controls the output current of the field effect transistor by controlling at least one of a bulk voltage or a gate voltage of the field effect transistor.
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
H03K 19/20 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits characterised by logic function, e.g. AND, OR, NOR, NOT circuits
33.
Surface-Modified Carbon Material, and Method for Producing Surface-Modified Carbon Material
The present invention is a surface-modified carbon material including chemical addends added to the surface of graphene, such that a one-dimensional periodicity corresponding to a large number of addition positions of the chemical addends can be observed in a Fourier-transformed image of a scanning probe microscopic image of the surface of graphene. The surface-modified carbon material of the present invention has a bandgap and therefore can be used as a sensor capable of electronically controlling an operation or another electronic device.
Provided is a hydrogen gas sensor capable of detecting hydrogen gas with high sensitivity, excellent response and recovery characteristics, and low power consumption. A hydrogen gas sensor 100 according to the present invention comprises: a substrate 10 having an insulating surface; first and second pad electrodes 12A and 12B formed on the insulating surface of the substrate 10; and a nanowire 14. The nanowire 14 is formed on the insulating surface of the substrate 10 to connect the first pad electrode 12A and the second pad electrode 12B, has a line width of 50-150 nm and a thickness of 10-60 nm, and comprises a hydrogen storage metal. The hydrogen gas sensor 100 causes a current to flow between the first pad electrode 12A and the second pad electrode 12B, and detects hydrogen gas on the basis of changes in the electrical signal detected between the first pad electrode 12A and the second pad electrode 12B.
G01N 27/12 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluidInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon reaction with a fluid
35.
MULTILAYER BODY, ELEMENT COMPRISING SAID MULTILAYER BODY AND METHOD FOR PRODUCING SAID MULTILAYER BODY
The present invention provides: a multilayer body; an element which comprises the multilayer body; and a method for producing the multilayer body. This multilayer body is provided with: a piezoelectric layer which is formed of a crystal of an oxide having piezoelectric properties; a metal layer; and a magnetic layer which is formed of a crystal of a Heusler alloy that is a ferromagnetic body. The piezoelectric layer, the metal layer and the magnetic layer are sequentially stacked in this order.
H01L 29/82 - Types of semiconductor device controllable by variation of the magnetic field applied to the device
H01F 10/16 - Thin magnetic films, e.g. of one-domain structure characterised by magnetic layers characterised by the composition being metals or alloys containing cobalt
H01F 41/28 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformersApparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for applying magnetic films to substrates from liquids by liquid phase epitaxy
A thermal radiator (21) includes first carbon nanotubes (CNTs) in which excitons produced based on energy from an energy source have energy consistent with a wavelength region within a range from the visible region to the near-infrared region, wherein the chemical potential of the excitons is maintained higher than zero.
INTERMETALLIC COMPOUND, CATALYST, PRODUCTION METHOD FOR METHANOL, PRODUCTION METHOD FOR CARBON MONOXIDE, AND PRODUCTION METHOD FOR INTERMETALLIC COMPOUND
Provided is an intermetallic compound that is excellent in terms of catalytic performance. An intermetallic compound according to an embodiment of the present invention includes a crystal lattice in which a first metal atom and the second metal atom exist at adjacent positions. The first metal atom is at least one selected from the group consisting of Pd, Rh, and Ir. The second metal atom is Mo. An X-ray diffraction spectrum before thermal desorption measurement has a first peak at a diffraction angle 2θ between 42° and 44°, and a second peak at a diffraction angle 2θ between 55° and 58°. After the thermal desorption measurement, the intensity of the first peak and the intensity of the second peak are equal to or lower than those before the thermal desorption measurement, and the BET specific surface area thereof is at least 1 m2/g.
C07C 29/157 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used containing iron group metals, platinum group metals, or compounds thereof containing platinum group metals or compounds thereof
The present invention is an antibacterial composition characterized by comprising a 2-phenyl benzimidazole-based compound and a salicylanilide-based compound. Further, the present invention is an antibacterial method for suppressing bacteria proliferation by using the above antibacterial composition, the method comprising a step of administering a 2-phenyl benzimidazole-based compound and a salicylanilide-based compound to bacteria having Na+-transporting V-ATPase and F-ATPase. The 2-phenyl benzimidazole-based compound is allowed to bind to the V-ATPase of bacteria to inhibit V-ATPase activity; and F-ATPase activity is inhibited by the proton concentration gradient made by F-ATPase being broken down by the salicylanilide-based compound.
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A01N 37/40 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio-analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio-analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
A01N 43/52 - 1,3-DiazolesHydrogenated 1,3-diazoles condensed with carbocyclic rings, e.g. benzimidazoles
The present invention provides a pharmaceutical composition that suppresses cell proliferation and has an anti-cancer effect with respect to pancreatic cancer and bile duct cancer. The present invention relates to a pharmaceutical composition containing, as an active ingredient, a substance that reduces an intracellular content of a ZIC5 protein, where the composition is used for treatment of pancreatic cancer or bile duct cancer; the pharmaceutical composition further containing an anti-cancer agent other than the substance that reduces the intracellular content of the ZIC5 protein; and the pharmaceutical composition further containing an anti-cancer agent other than the substance that reduces the intracellular content of the ZIC5 protein.
A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine
A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 31/585 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
A nucleic acid analog in which a cationic artificial nucleic acid and a hydrophilic polymer are bonded to each other. The cationic artificial nucleic acid has a backbone structure including a constituent unit in which a base is bonded to a ring structure selected from ribose and deoxyribose, and a linking structure linking two constituent units, the linking structure, in a cationic state, has a cationic group selected from the group consisting of the formulae (C1) to (C7), and the cationic artificial nucleic acid can associate by electrostatic interaction between a phosphate group of another nucleotide and the cationic group, wherein R1 to R3 represent hydrogen or an alkyl group, and may be the same or different, and Ring is a cyclic compound and may be a heterocyclic ring.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
To provide a gas sensor with fast response and high sensitivity to oxygen gas. Disclosed is a gas sensor 100 including: a substrate 10; a first pad electrode 12A and a second pad electrode 12B; a nanowire 14 made of a specific metal; and an oxide layer 16 made of a high-resistance semiconductor that is an oxide of a metal different from a metal constituting the nanowire 14. The first pad electrode 12A and the second pad electrode 12B are formed on or above the substrate 10. The nanowire 14 connects the first pad electrode 12A and the second pad electrode 12B and is formed on or above the substrate 10.
To provide a gas sensor with fast response and high sensitivity to oxygen gas. Disclosed is a gas sensor 100 including: a substrate 10; a first pad electrode 12A and a second pad electrode 12B; a nanowire 14 made of a specific metal; and an oxide layer 16 made of a high-resistance semiconductor that is an oxide of a metal different from a metal constituting the nanowire 14. The first pad electrode 12A and the second pad electrode 12B are formed on or above the substrate 10. The nanowire 14 connects the first pad electrode 12A and the second pad electrode 12B and is formed on or above the substrate 10.
The oxide layer 16 is formed in contact with the nanowire 14. This contact between the nanowire 14 and the oxide layer 16 provides fast response and high sensitivity to oxygen gas.
G01N 27/04 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions
42.
Compound and polymer compound containing the compound
Provided is a compound having higher fluorescence quantum yield and higher optical stability than a conventional FLAP and a polymer compound containing the compound.
2: Formulas (2-1) to (2-3):
2.
To provide a suitable method of producing an ordered-alloy ferromagnetic nanowire structure. Disclosed is a method of producing an ordered-alloy ferromagnetic nanowire structure, the method including: forming a nanowire on or above a substrate, the nanowire having a width of 100 nm or less and a length of at least twice the width, and made of an iron group element and a platinum group element; and subjecting the nanowire to heat treatment to obtain an ordered-alloy ferromagnetic nanowire structure in which an ordered-alloy ferromagnetic nanowire made of an ordered alloy of the iron group element and the platinum group element is formed on or above the substrate.
B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
B82Y 25/00 - Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
B82Y 40/00 - Manufacture or treatment of nanostructures
C22C 5/04 - Alloys based on a platinum group metal
C23C 14/16 - Metallic material, boron or silicon on metallic substrates or on substrates of boron or silicon
C23C 14/22 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
H01F 1/147 - Alloys characterised by their composition
44.
CHARACTERISTICS MEASUREMENT DEVICE FOR OBJECT TO BE MEASURED AND CHARACTERISTICS MEASUREMENT METHOD FOR OBJECT TO BE MEASURED
A characteristics measurement device for an object according to the invention comprises a sound wave generator that emits a sound wave; a receiver that receives from the object an electromagnetic field generated by the sound wave being irradiated to the object; a sound wave medium between the sound wave generator and the object the electromagnetic field separated from a reverberating electromagnetic field caused by reverberating vibrations of the sound wave generator in time; an inverse diffuse that inversely diffuses the electromagnetic field received by the receiver using a reference signal associated with the sound wave; and a measurement unit that extracts at least one characteristic selected from a group consisting of electrical characteristics, magnetic characteristics, electromechanical characteristics and magnetomechanical characteristics of the object based on at least one measurement selected from a group consisting of intensity, phase and frequency of the inversely diffused electromagnetic field.
Disclosed is a compound represented by general formula (1) or a salt thereof. In the formula, each of R1and R2independently represents an alkyl group having 1 to 4 carbon atoms; R1and R2may combine with each other to form a ring together with carbon atoms to which R1and R2are bonded; and each R3 independently represents an alkylene group having 1 to 4 carbon atoms. Also disclosed are nanoparticles that each contain the compound or a salt thereof. Also disclosed is a medicine that contains the compound or a salt thereof. Also disclosed is a method for producing nanoparticles, the method comprising a step in which a water-miscible organic solvent solution of the compound or a salt thereof is injected into water.
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
A61K 31/4745 - QuinolinesIsoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
Provided is a low-toxicity zwitterion which is capable of dissolving high concentrations of cellulose. The present invention pertains to a zwitterion represented by general formula (1): R1-A-R2-(OR3)n-B (R1222)m-. A is the cationic section of the zwitterion and represents a cation selected from an imidazolium cation, a phosphonium cation, an ammonium cation, a sulfonium cation, a pyrazolium cation, a pyridinium cation, a pyrrolidinium cation, a morpholinium cation, a cyclopropenium cation and a piperidinium cation. R2represents a C1-4 alkylene group. R333 -, -COO-, -P=O(OR4)O-and -OP=O(OR5)O-. R4and R5may be identical or different, and are alkyl groups which may have a hydrogen atom or a C1-8 hetero atom (however, when n is 0, B is -P=O(OR4)O-or -OP=O(OR5)O-)).
C07D 233/64 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
A quantum entanglement generator comprises two superconducting qubit elements, each having three electrodes, where n is an integer greater than or equal to, a coupling resonator disposed between adjacent superconducting qubit elements and a waveguide capacitively coupled to each of the superconducting qubit elements and to each other. The coupling resonator generates quantum entanglement between the adjacent superconducting qubit elements by acting a two-qubit gate between the adjacent superconducting qubit elements. The superconducting qubit elements emit the quantum entanglement as a propagating microwave photon into the waveguide, thereby generating a two-dimensional cluster state.
An electron microscope of an embodiment according to the present invention includes an electron gun for irradiating a sample with electrons; an electron detector for detecting the electrons with which the sample is irradiated; a photon detector for detecting photons emitted from the sample when the sample is irradiated with the electrons; and a computing device that computes, for each of the detected photons, a time difference between the time of irradiation of the sample with the electron and the time of emission of the photon from the sample, based on the time of detection of the electron by the electron detector and the time of detection of the photon by the photon detector, and that computes electron-photon time correlation indicating the distribution of the time difference.
H01J 37/26 - Electron or ion microscopesElectron- or ion-diffraction tubes
G01N 23/2251 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using electron or ion microprobes using incident electron beams, e.g. scanning electron microscopy [SEM]
H01J 37/22 - Optical or photographic arrangements associated with the tube
H01J 37/244 - DetectorsAssociated components or circuits therefor
This biological substance treatment method involves preparing a flow cell 1 comprising: a chamber array device 11 provided with a plurality of chambers 14 in which one of the chambers is 1 nanoliter or less; and a cover body 21 defining a flow path 40 that is provided so as to be in communication with an opening of the chamber 14 and shared by the plurality of chambers 14. Next, prepared are DEX and PEG, which are both water-soluble and phase-separate when left to stand at room temperature. The property of DEX is that DEX phase-separates into the chamber 14 and organic substances are preferentially distributed to DEX more than PEG. Then, the organic substances are mixed in PEG. DEX is allowed to flow in the flow path 40 so that DEX is filled in the chamber 14 and in the flow path 40. Next, PEG is allowed to flow in the flow path 40, and as a result, DEX, which is remaining there, is pushed out and DEX and PEG come into contact with each other. Consequently, the organic substances are concentrated in DEX in the chamber 14.
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
Provided are: nanosheet-like particles of a polythiophene-based compound, which cannot be obtained using conventional methods and which have a thickness of 10 nm or less; and a method for producing same. In particular, provided is a dispersion liquid composition containing nanosheet-like particles of a polythiophene-based compound, in which particles are stably present without aggregating. These nanosheet-like particles of a polythiophene-based compound have a thickness of 0.5-10 nm and an aspect ratio (maximum width/thickness of a particle) of 100 or more.
A metal-supported material including a transition metal excluding Group 4 elements supported on a binary composite oxide. The composite oxide includes a metal element expressed by AnXy, where A represents a lanthanoid that is in a partially or entirely trivalent state, X represents an element that is a Group-2 element in a periodic table selected from the group consisting of Ca, Sr, and Ba, or a lanthanoid, and that is different from A, n satisfies 0
C01F 17/241 - Compounds containing only rare earth metals as the metal element oxide or hydroxide being the only anion containing two or more rare earth metals, e.g. NdPrO3 or LaNdPrO3
B01J 23/10 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of rare earths
B01J 23/46 - Ruthenium, rhodium, osmium or iridium
C01F 17/32 - Compounds containing rare earth metals and at least one element other than a rare earth metal, oxygen or hydrogen, e.g. La4S3Br6 oxide or hydroxide being the only anion, e.g. NaCeO2 or MgxCayEuO
A thermoelectric conversion device includes thermoelectric layers and connection layers that are alternately provided in a first direction parallel to surfaces of the thermoelectric layers, and are connected to each other, thermally conductive layers that are connected to the respective connection layers, and extends in a second direction intersecting the surfaces, a first insulating layer that has a smaller thermal conductivity than the thermally conductive layers, and a second insulating layer that has a smaller thermal conductivity than the first insulating layer, is provided between the first insulating layer and the thermoelectric layers, and has a thickness equal to or greater than ¼ of a distance between an end of the thermally conductive layer at a side of one of the thermoelectric layers and a center of another of the connection layers in the first direction, the thermally conductive layers penetrating through the first and second insulating layers.
H10N 10/17 - Thermoelectric devices comprising a junction of dissimilar materials, i.e. devices exhibiting Seebeck or Peltier effects operating with only the Peltier or Seebeck effects characterised by the structure or configuration of the cell or thermocouple forming the device
12cc12c122|-δ that is shifted by a predetermined frequency δ from the first cross-Labi transition drive pulse. The predetermined frequency shift δ is a value that erases a residual ZZ interaction between the first data quantum bit 11 and the second data quantum bit 12.
G06N 10/40 - Physical realisations or architectures of quantum processors or components for manipulating qubits, e.g. qubit coupling or qubit control
G06F 7/38 - Methods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation
The present invention provides a method for recycling polymer fine particles, the method being applicable to various polymers. This method for recycling polymer fine particles comprises (A) a step for dismantling a first polymer fine particle molded body, which has been obtained by molding first polymer fine particles, into second polymer fine particles by applying external stimuli to the first polymer fine particle molded body.
A majority-decision logic device 1 comprises a non-magnetic semiconductor layer 10 made of a material that, when irradiated with light having at least two kinds of mutually different polarization states, generates electron spin waves having different phases corresponding to the polarization states. The non-magnetic semiconductor layer 10 comprises: three or more input portions to which a light signal is input; and at least one output portion that outputs a result of interference of the electron spin waves. The length of the distance between adjacent input portions as projected in the direction of vibration of the electron spin waves is an integer multiple of the wavelength of the electron spin waves.
This photoelectric conversion element (100) comprises, in the following order as a photoelectric conversion layer (103): a first layer (104) configured from a plurality of particles containing a perovskite structure (201) as a main component, or from an aggregate or thin film of the particles; a second layer (105) configured from a plurality of particles containing an inorganic transition metal (205) as a main component, or an aggregate or thin film of the particles; and a third layer (106) configured from a plurality of particles containing an organic ligand (206) as the main component, or an aggregate or thin film of the particles. The inorganic transition metal (205) in the second layer (105) is different from a central metal contained in the perovskite structure (201). At an interface (S1) between the first layer (104) and the second layer (105), the perovskite structure (201) and the inorganic transition metal (205) in the second layer (105) form a one-to-one layer arrangement. At an interface (S2) between the second layer (105) and the third layer (106), the inorganic transition metal (205) in the second layer (105) and the organic ligand (206) in the third layer (106) together form an organometallic complex layer (108) composed of an organometallic complex (208).
H10K 30/60 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation in which radiation controls flow of current through the devices, e.g. photoresistors
H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
H10K 85/40 - Organosilicon compounds, e.g. TIPS pentacene
H10K 85/50 - Organic perovskitesHybrid organic-inorganic perovskites [HOIP], e.g. CH3NH3PbI3
Provided is an OLED device 10 including a plurality of organic semiconductor layers sandwiched between a pair of electrodes 3 and 4. The organic semiconductor layers include a first organic semiconductor layer 1 containing a first organic semiconductor material, and a second organic semiconductor layer 2 containing a second organic semiconductor material and a third organic semiconductor material, the first organic semiconductor layer and the second organic semiconductor layer form a joining surface, and the first organic semiconductor material and the second organic semiconductor material satisfy requirement and the like relating to a predetermined energy level.
The present invention provides a micro two-phase droplet generating device that does not require separate through-holes corresponding to a plurality of two-phase dispersed parallel continuous flow channels. The micro two-phase droplet generating device of the present application comprises a row of a plurality of microflow channels, liquid transfer ports, and a slit, and is configured so as to form two-dispersion phase parallel continuous flows at first connection sites between the plurality of microflow channels, in which a first dispersion phase flows, and the slit, through which a second dispersion phase flows. A continuous phase is fed to second connection sites between the plurality of microflow channels, in which the two-dispersion phase parallel continuous flows flow, and another liquid transfer port, which is preferably a second slit, downstream of the slit, and the two-dispersion phase parallel continuous flows are sheared at the second connection sites, whereby two-phase droplets, and in particular, core-shell or Janus two-phase droplets, can be generated, and a product can be collected from a discharge port.
A switching circuit includes a first switching element that has a first control terminal, a connection state between a power generation element and an electric storage device being controlled in accordance with a voltage applied to the first control terminal, and a control circuit configured to output a first voltage to the first control terminal until a voltage difference between both ends of the electric storage device becomes a first predetermined value larger than an initial state when the voltage difference increases from the initial state with time, and output a second voltage to the first control terminal until the voltage difference becomes lower than a second predetermined value smaller than the first predetermined value when the voltage difference exceeds the first predetermined value, the first voltage being a voltage that keeps the first switching element on, the second voltage being a voltage that keeps the first switching element off.
H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load
H02M 1/08 - Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters
H02M 3/155 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only
H02M 7/04 - Conversion of AC power input into DC power output without possibility of reversal by static converters
H03K 3/353 - Generators characterised by the type of circuit or by the means used for producing pulses by the use, as active elements, of field-effect transistors with internal or external positive feedback
H03K 17/06 - Modifications for ensuring a fully conducting state
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
A switching circuit includes a switching element of a field-effect type, the switching element being configured to switch between an ON state and an OFF state in accordance with a potential of a control terminal, and a control circuit configured to supply a potential of a first level to the control terminal when maintaining one state of the ON state and the OFF state of the switching element, and make the control terminal floating after charging or discharging the control terminal via a resistor and supply a potential of a second level to the control terminal when switching the switching element from the one state to another state of the ON state and the OFF state, the first level bringing the switching element into the one state, the second level bringing the switching element into said another state.
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
H03K 17/06 - Modifications for ensuring a fully conducting state
H03K 17/74 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of diodes
H02M 3/155 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only
H02M 1/08 - Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters
H02M 7/04 - Conversion of AC power input into DC power output without possibility of reversal by static converters
61.
Methods for producing alpha-keto acid and pyruvic acid
The purpose of the present invention is to provide a preservative composition which is used in place of or in combination with a cell-penetrating substance such as DMSO that has been commonly used in a culture medium for cryopreservation use and a liquid for cryopreservation use to reduce the toxicity of the cell-penetrating substance and improve the cryopreservation effect of the cell-penetrating substance. Provided are: a zwitterionic polymer represented by general formula (1), or a labelled product of the zwitterionic polymer; and a preservative composition for biological samples, which contains the zwitterionic polymer or the labelled product. (In the formula, X1and X2may be the same as or different from each other, and each independently represent a carbon atom or a nitrogen atom; Y1and Y2may be the same as or different from each other, and each independently represent an anion selected from -COO-33 -, -OP=O(H)O-33)O-and -OP=O(OR1)O-; Z represents a hydrogen atom, an aromatic hydrocarbon group having 6 to 10 carbon atoms in which an alkyl group may be substituted, a 5- to 6-membered aromatic heterocyclic group in which an alkyl group may be substituted, a nitrogenated heterocyclic ammonium salt in which an alkyl group may be substituted, a tetraalkyl ammonium salt, a tetraphenyl phosphonium salt, a tetraalkyl phosphonium salt, a trialkyl sulfonium salt, or a linear or branched alkyl group having 1 to 22 carbon atoms which may have 1 to 3 oxygen atoms in a molecular chain thereof; e and f each independently represent an integer of 0 or 1; l, m and n are numerical values respectively representing the content ratios of repeating units corresponding thereto and respectively satisfying the formulae 0 < l ≤ 1, 0 ≤ m < 1, 0 ≤ n < 1 and l+m+n = 1; and p, q, r, s and t each independently represent an integer of 0 to 6.)
C08F 26/06 - Homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
C08F 226/06 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
C08K 3/01 - Use of inorganic substances as compounding ingredients characterised by their specific function
C08L 5/00 - Compositions of polysaccharides or of their derivatives not provided for in group or
C08L 39/00 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogenCompositions of derivatives of such polymers
C08L 39/04 - Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
C12N 1/04 - Preserving or maintaining viable microorganisms
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
This nonvolatile storage device comprises a plurality of nonvolatile storage elements, wherein: the nonvolatile storage elements each comprise a semiconductor layer including a metal oxide, a gate electrode facing the semiconductor layer, and a gate insulating layer formed of antiferroelectrics and provided between the semiconductor layer and the gate electrode, and the electron affinity of a first material constituting the gate electrode is smaller than that of a second material constituting the semiconductor layer, and the second material is an n-type semiconductor; or the electron affinity of the first material constituting the gate electrode is greater than that of the second material constituting the semiconductor layer, and the second material is a p-type semiconductor.
H01L 29/788 - Field-effect transistors with field effect produced by an insulated gate with floating gate
H01L 29/792 - Field-effect transistors with field effect produced by an insulated gate with charge trapping gate insulator, e.g. MNOS-memory transistor
A spike generation circuit includes a first CMOS inverter connected between a first power supply and a second power supply, an output node of the first CMOS inverter being coupled to a first node that is an intermediate node coupled to an input terminal to which an input signal is input, a switch connected in series with the first CMOS inverter, between the first power supply and the second power supply, a first inverting circuit that outputs an inversion signal of a signal of the first node to a control terminal of the switch, and a delay circuit that delays the signal of the first node, outputs a delayed signal to an input node of the first CMOS inverter, and outputs an isolated output spike signal to an output terminal.
H03K 19/20 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits characterised by logic function, e.g. AND, OR, NOR, NOT circuits
65.
THIN FILM TRANSISTOR, DISPLAY DEVICE, AND METHOD FOR MANUFACTURING THIN FILM TRANSISTOR
In an embodiment, a thin film transistor is formed on a substrate, the thin film transistor includes a channel formed by at least part of a metal oxide semiconductor layer containing at least indium (In), a gate electrode, a gate insulating layer arranged between the channel and the gate electrode, a source electrode connected to the metal oxide semiconductor layer, and a drain electrode connected to the metal oxide semiconductor layer. For example, the average concentration of carbon atoms in an area from a surface to the depth of 5 nm of the channel is 1.5×1021 cm−3 or less, whereby a threshold shift due to a voltage stress can be effectively reduced.
H01L 27/12 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being other than a semiconductor body, e.g. an insulating body
A superconducting complex quantum computing circuit includes a circuit substrate in which a wiring pattern of a circuit element including quantum bits and measurement electrodes, and ground patterns are formed, and through-electrodes connecting the ground pattern formed on a first surface of the substrate surface and the ground pattern formed on a second surface; a first ground electrode including a first contact portion in contact with the ground patterns, and a first non-contact portion having a shape corresponding to a shape of the wiring pattern; a second ground electrode including a second contact portion in contact with the ground pattern; a control signal line provided with a contact spring pin at a tip; and a pressing member that presses the first ground electrode against the first surface of the circuit substrate or presses the second ground electrode against the second surface of the circuit substrate.
One measurement device 100 of the present invention comprises: a sound-wave transmission unit 120 that transmits sound waves to a measurement object 10; detection units 130A, 130B that detect electro-magnetic fields which are generated by the measurement object 10 as a result of the sound waves having been emitted from the sound-wave transmission unit, the electro-magnetic fields being from a plurality of mutually different directions or in a plurality of mutually different locations; and an evaluation unit 152 that evaluates characteristics pertaining to the anisotropy of the measurement object 10, on the basis of the results of detection of the electro-magnetic fields by the detection units 130A, 130B.
G01N 22/00 - Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
G01N 24/00 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
A composite oxide including an oxide of a metal element L and an oxide of a metal element N, and represented by a composition of general formula LnN1-n, wherein the metal element L is a Group 1 element, a Group 2 element, or a Group 1 element and a Group 2 element, the metal element N comprises a Group 1 or Group 2 element other than the metal element L, n is 0.001 or more and 0.300 or less, the oxide of the metal element L and the oxide of the metal element N form no solid solution, and oxide particles of the metal element L are deposited on surfaces of oxide particles of the metal element N. Also, a metal-carrier material and an ammonia synthesis catalyst having, supported on this composite oxide, particles of at least one metal M selected from the group consisting of cobalt, iron, and nickel.
DEVICE FOR DETECTING PREDICTOR OF ABRUPT CHANGE IN SYSTEM STATE, METHOD FOR DETECTING PREDICTOR OF ABRUPT CHANGE IN SYSTEM STATE, PROGRAM FOR DETECTING PREDICTOR OF ABRUPT CHANGE IN SYSTEM STATE, CONGESTION PREDICTOR DETECTION DEVICE, CONGESTION PREDICTOR DETECTION METHOD, CONGESTION PREDICTOR DETECTION PROGRAM, PRE-DISEASE STATE DETECTION DEVICE, PRE-DISEASE STATE DETECTION METHOD, PRE-DISEASE STATE DETECTION PROGRAM, AND RECORDING MEDIUM
A predictor detection device 2 that detects a predictor of an abrupt change in state of a system of interest is provided with: a classification means 11 which, on the basis of correlations of chronological changes in measurement data related to a plurality of nodes of which the system of interest is composed, classifies the plurality of nodes into a plurality of clusters; and a means 12 which selects a cluster corresponding to a pre-set selection condition on the basis of the correlations of chronological changes in the measurement data of the nodes in each of the classified clusters and the chronological changes in the measurement data between all the nodes, and toggles between detection of a node included in the selected cluster as a dynamic network marker serving as a predictor of an abrupt change in state, and verification as to whether a pre-stored specific node can be detected as a dynamic network marker.
G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
G16B 25/10 - Gene or protein expression profilingExpression-ratio estimation or normalisation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
Provided is a compound that includes a peptide structure represented by formula (p1) or (p2). Also provided is a method for producing a droplet using the compound. Xa is an amino acid residue having a hydrophilic side chain. Xb is an amino acid residue having a side chain represented by formula (b1). Xc and Xd each independently an amino acid residue or glycine residue having a hydrophobic side chain. n is an integer between 1 and 3. Ar1is an optionally substituted aryl group or heteroaryl group. Ar2nnnXaXbXa.
Provided is a silicon bulk thermoelectric conversion material in which the thermoelectric performance is improved compared to the past. Also provided is a method for manufacturing a silicon bulk thermoelectric conversion material in which the heat conductivity is reduced and the thermoelectric performance is improved compared to the past. A silicon bulk thermoelectric conversion material according to an embodiment of the present invention comprises: an accommodation step for placing a silicon powder containing silicon nanoparticles between a first electrode member and a second electrode member of a heating unit provided with the first electrode member, the second electrode member, and an electroconductive cylindrical member with which at least one of the first electrode member and the second electrode member slidably fits; a heating step for channeling a current while applying a pressure of 12 MPa or less between the first electrode member and the second electrode member and thereby heating the silicon powder; and a cooling step for cooling the heated silicon powder.
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japan)
Inventor
Abe Hiroshi
Abe Naoko
Inagaki Masahito
Nakashima Yuko
Kimura Yasuaki
Hashiya Fumitaka
Abstract
The present invention is capped RNA which has a translated region that begins with a start codon and encodes proteins, and an upstream region that is located upstream of the start codon. The capped RNA is provided with a branched part having a cap structure. Further, the branched part preferably has at least one structure of (a) to (c). (a) A structure which has a sequence complementary to a part or the entirety of an untranslated region and in which a capped probe having a cap structure is hybridized to the untranslated region; (b) a structure in which there is provided, in a portion of an untranslated region, a branched chain branching from a main chain constituting the RNA, the branched chain having a cap structure provided thereto; and (c) a structure in which the 5' terminus of a main chain of an untranslated region has a branch structure that divides into two or more branches, and in which each of the branches is provided with a cap structure.
[Solution] The present invention relates to a method for partially oxidizing an alkane, including contacting an alkane with a supported catalyst in a presence of an oxidizer to convert the alkane into an aldehyde, wherein the supported catalyst is composed of a bimetallic oxide and a support carrying the bimetallic oxide, and the bimetallic oxide is represented by the following formula and includes oxygen and two metals selected from metals of groups 8 to 10 of the periodic table:
[Solution] The present invention relates to a method for partially oxidizing an alkane, including contacting an alkane with a supported catalyst in a presence of an oxidizer to convert the alkane into an aldehyde, wherein the supported catalyst is composed of a bimetallic oxide and a support carrying the bimetallic oxide, and the bimetallic oxide is represented by the following formula and includes oxygen and two metals selected from metals of groups 8 to 10 of the periodic table:
AmBnOx
wherein the bimetallic oxide and support are each a metal selected from metallic elements of groups 8 to 10 of the periodic table; the bimetallic oxide and support are not the same metallic element; m, n, and x mean amounts ((mmol)) of the bimetallic oxide, the support, and oxygen, respectively, per 1 g of the supported catalyst; m is more than 0 [mmol/g-cat] and less than 1 [mmol/g-cat]; n is more than 0 [mmol/g-cat] and less than 1 [mmol/g-cat]; and x is a value [mmol/g-cat] satisfying oxidation states of the bimetallic oxide and the support.
C07C 45/28 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by oxidation of —CHx-moieties
A method for manufacturing a porous film includes: a first step of preparing droplets (D) which are formed from a first liquid into spheres with a predetermined diameter of 10 μm or more and 2000 μm or less and a second liquid (L2) which includes a curing agent which cures by imparting energy or a curing agent which cures due to change in pH and includes droplets dispersed therein; a second step of injecting the droplets and the second liquid into a gap between a pair of substrates (31 and 32); a third step of curing the second liquid to form an external phase; and the fourth step of removing the droplets in the external phase to form hole sections.
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
C12M 1/00 - Apparatus for enzymology or microbiology
B29C 41/12 - Spreading-out the material on a substrate
B29C 67/20 - Shaping techniques not covered by groups , or for porous or cellular articles, e.g. of foam plastics, coarse-pored
B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
B29D 11/00 - Producing optical elements, e.g. lenses or prisms
B29C 39/00 - Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressureApparatus therefor
B29C 39/02 - Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressureApparatus therefor for making articles of definite length, i.e. discrete articles
B01D 71/40 - Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
A ferroelectric memory device has a three-dimensional stacked structure with multiple ferroelectric memory elements arranged in series. The ferroelectric memory device has a semiconductor member having a columnar shape including a metal oxide, a ferroelectric layer containing hafnium oxide and surrounding the semiconductor member in contact with a side surface of the semiconductor member, and a plurality of gate electrodes arranged along a longitudinal direction of the semiconductor member and facing a side surface of the semiconductor member through the ferroelectric layer. The semiconductor member is a continuous member from its outer periphery to its central axis.
H10B 51/20 - Ferroelectric RAM [FeRAM] devices comprising ferroelectric memory transistors characterised by the three-dimensional arrangements, e.g. with cells on different height levels
H10B 51/30 - Ferroelectric RAM [FeRAM] devices comprising ferroelectric memory transistors characterised by the memory core region
76.
OXYNITRIDE-HYDRIDE, METAL-SUPPORTED MATERIAL CONTAINING OXYNITRIDE-HYDRIDE, AND AMMONIA SYNTHESIS CATALYST
The present invention is related to an oxynitride-hydride which is capable of achieving both stabilization and improvement of catalyst performance when used as a support, and the oxynitride-hydride can be easily synthesized. The oxynitride-hydride is represented by the following general formula (1),
The present invention is related to an oxynitride-hydride which is capable of achieving both stabilization and improvement of catalyst performance when used as a support, and the oxynitride-hydride can be easily synthesized. The oxynitride-hydride is represented by the following general formula (1),
AnBmOl-xNyHz (1)
wherein in the general formula (1), x represents a number represented by 0.1≤x≤3.5; y represents a number represented by 0.1≤y≤2.0; and z represents a number represented by 0.1≤z≤2.0.
POLYMER COMPOUND, REACTIVE COMPOUND, POLYMER CROSSLINKING AGENT, POLYMER MODIFIER, METHOD FOR FORMING A CROSSLINKED SECTION, METHOD FOR POLYMER MODIFICATION, AND METHOD FOR POLYMERIZING AND METHOD FOR DECOMPOSING POLYMER COMPOUND
This polymer compound contains a structure obtained by bonding conjugated carbon atoms having condensed polycyclic aromatic ring groups with silicon atoms, the bonding being cleavable by a cooperative effect between light irradiation and acid.
C08F 30/08 - Homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing silicon
C07F 7/08 - Compounds having one or more C—Si linkages
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other than movies, television programs, advertising and
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recordings; rental of image-recorded magnetic tapes; rental
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80.
THIN FILM AND METHOD FOR PRODUCING SAME, CIRCULARLY POLARIZED LIGHT DETECTION ELEMENT, DEVICE AND METHOD
This thin film is a thin film for detecting circularly polarized light, and includes a plurality of inorganic layers constituting a layered structure and/or a plurality of inorganic chains constituting a chain structure, which are formed of a perovskite type substance, and chiral molecules incorporated in at least a part of a boundary part between the adjacent inorganic layers and/or between the inorganic chains, wherein the chiral molecules include only one of S-form chiral molecules and R-form chiral molecules or chiral molecules with a higher abundance proportion of one of S-form chiral molecules and R-form chiral molecules than an abundance proportion of the other of S-form chiral molecules and R-form chiral molecules, and wherein the crystal structure of the perovskite type substance is oriented in a predetermined direction.
H01L 31/08 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof in which radiation controls flow of current through the device, e.g. photoresistors
G01J 4/04 - Polarimeters using electric detection means
H10K 71/12 - Deposition of organic active material using liquid deposition, e.g. spin coating
H10K 85/50 - Organic perovskitesHybrid organic-inorganic perovskites [HOIP], e.g. CH3NH3PbI3
81.
LIGHT-DRIVEN FUEL CELL, CATHODE CATALYST FOR SAME, ANODE CATALYST FOR SAME, AND METHANOL PRODUCTION METHOD COMPRISING CONVERTING METHANE INTO METHANOL
A light-driven fuel cell includes a cathode, an anode, and a proton-permeable membrane between the anode and the cathode. The anode includes a photocatalyst for anaerobic methane oxidation reaction, and when the anode is supplied with methane and water and is irradiated with light, methanol, protons and electrons are generated by anaerobic methane oxidation reaction from the methane and the water supplied to the anode; the protons pass through the proton-permeable membrane and move to the cathode; and the electrons move to the cathode via an external circuit. The cathode includes a photocatalyst for aerobic methane oxidation reaction, and when the cathode is supplied with methane and oxygen and is irradiated with light, methanol and water are generated by aerobic methane oxidation reaction from the methane and the oxygen supplied to the cathode and the protons and the electrons moved from the anode.
C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
H01M 8/22 - Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elementsFuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen
H01M 16/00 - Structural combinations of different types of electrochemical generators
82.
Power conversion circuit, semiconductor device, and electronic device
A power conversion circuit includes a first capacitor coupled between an input terminal and a reference potential, a second capacitor coupled between an output terminal and a reference potential, an inductor coupled between the input terminal and the output terminal, storing magnetic field energy when at least part of an input current and a current output from the first capacitor flows through the inductor as a first current, and inducing a second current for charging the second capacitor by the magnetic field energy, and a switching element that is turned on and off at a substantially constant cycle, has a substantially constant period during which the switching element is ON in one cycle, is turned on to cause the first current to flow through the inductor, and is OFF when the second current flows through the inductor.
H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load
83.
mRNA and Method for Producing Same, Device for Producing Protein, and Method for Producing Protein
A mRNA for the synthesis of a protein, including a translation region containing a start codon and a stop codon and an untranslated region positioned on the 5′-end side of the start codon, in which some phosphate groups within the range of at least from the 5′end of the untranslated region to 15 nt on the 3′-end side of the start codon are substituted with phosphorothioate groups, is provided. A method for producing an mRNA, including: a step of preparing a DNA template; a step of preparing an unmodified NTP containing ATP, GTP, CTP, and UTP, and a modified NTP in which at least one kind of phosphate group of the unmodified NTP is substituted with a phosphorothioate group; and a step of performing a transcription reaction with RNA polymerase using the DNA template as a template and the unmodified NTP and the modified NTP as substrates, is also provided.
A quantum gate device includes a first superconducting circuit which includes at least one of Josephson devices in an annular circuit including a superconducting wire and resonates at a first resonance frequency, a second superconducting circuit which includes at least one of Josephson devices in an annular circuit including a superconducting wire and resonates at a second resonance frequency, a connection unit which includes a capacitor and a superconducting wire provided at each electrode of the capacitor and connects the first and second circuits, a magnetic field application means applying a magnetic field to one or both of the first and second circuits, a quantum gate control electromagnetic wave irradiation unit irradiating one of the first and second circuits with a control electromagnetic wave, and an unnecessary transition suppression electromagnetic wave irradiation unit irradiating one of the first and second circuits with an unnecessary interaction suppression electromagnetic wave.
A core-shell particle which includes a core-shell structure includes an inorganic nanoparticle having a light wavelength conversion ability and a coating layer formed on a surface of the inorganic nanoparticle and formed of an inorganic perovskite type substance.
H10K 30/35 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising bulk heterojunctions, e.g. interpenetrating networks of donor and acceptor material domains comprising inorganic nanostructures, e.g. CdSe nanoparticles
B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
CATALYST COMPOSITION, METHOD FOR PROMOTING CATALYTIC ACTIVITY, METHOD FOR PRODUCING CATALYST COMPOSITION, AND AMMONIA SYNTHESIS METHOD USING CATALYST COMPOSITION
mnpqwstt. (In formula (1), L represents at least one selected from the group consisting of transition elements and Al, A represents at least one selected from the group consisting of Si, O, N, and C, m represents a numerical value of 1 or more, and n represents a numerical value of 0 or more. In formula (2), M represents one or more selected from the group consisting of typical elements and transition elements, M does not include Al and Ca at the same time, p represents a numerical value of 0 or more, q represents a numerical value of 0 or more, w represents a numerical value of 0 or more, s represents a numerical value of 0 or more, and t represents a numerical value of 0 or more. q, w, s, and t are not 0 at the same time.
B01J 23/58 - Platinum group metals with alkali- or alkaline earth metals or beryllium
B01J 23/63 - Platinum group metals with rare earths or actinides
B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
B01J 23/89 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with noble metals
A microdroplet/bubble-generating device comprising a slit and a row of a plurality of microflow paths is constructed, in such a manner that either a continuous phase or dispersion phase is supplied to the slit, and so that the end of the slit, the other supply port for the continuous phase or dispersion phase and the liquid recovery port are connected. The plurality of microflow paths each have a narrow part where the cross-sectional area of the flow channel is locally narrowed adjacent to or near the connection point between the slit and the microflow path. The continuous phase and dispersion phase that have met at the connection points flow into the narrow parts, and the dispersion phase is sheared at the narrow parts with the continuous phase flow as the driving force, forming droplets or gas bubbles of the dispersion phase. The product is recovered from the liquid recovery port.
B01F 33/3011 - Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
B01F 35/00 - Accessories for mixersAuxiliary operations or auxiliary devicesParts or details of general application
B01F 25/314 - Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
B01F 23/232 - Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using flow-mixing means for introducing the gases, e.g. baffles
B81B 1/00 - Devices without movable or flexible elements, e.g. microcapillary devices
88.
NUCLEIC ACID STRAND CLEAVING METHOD, NUCLEIC ACID STRAND CLEAVING DEVICE, DOUBLE-STRANDED DNA PRODUCTION METHOD, AND DOUBLE-STRANDED DNA PRODUCTION DEVICE
A nucleic acid strand cleaving method that is characterized by comprising a nucleic acid preparation step in which a nucleic acid to be cleaved that has a structure indicated in formula (1) is prepared, and a cleaving step in which the nucleic acid to be cleaved is cleaved at X in formula (1) by reacting the nucleic acid to be cleaved with a cleaving agent, and a nucleic acid that has a structure indicated in formula (2) is generated, wherein the cleaving agent is metal nanoparticles that include atoms selected from the group consisting of silver, mercury, and cadmium. [Formula 1] (B indicates a base, and X indicates sulfur or selenium. NucA comprises at least one nucleotide, is part of the nucleic acid to be cleaved, and indicates a section on the 5'-end side, relative to X. NucB comprises at least one nucleotide, is part of the nucleic acid to be cleaved, and indicates the 3'-end side, relative to X.)
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
This electron-trapping device 1 comprises a low-temperature device 1, a superconducting circuit 10, and a hot bath 60. The superconducting circuit 10 and the hot bath 60 are arranged in the low-temperature device 40. This makes it possible for the superconducting circuit 10 to operate and keeps the hot bath 60 at a given low temperature (e.g., about 20 mK). The superconducting circuit 10 is provided with a cooling resonator 20, a microwave resonator 22, and an electron-trapping region 50. The superconducting circuit 10 has a microstructure in which electrodes that face each other are disposed at positions having line symmetry about a center line passing through the electron-trapping region and are surrounded by a superconductor so that the electron-trapping region 50 is configured from a plurality of facing electrodes.
B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
G06N 10/00 - Quantum computing, i.e. information processing based on quantum-mechanical phenomena
H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions
90.
Composite Material Including COF, Heat Dissipation/Storage Member, and Method for Producing Said Composite Material, and COF Single Crystal and Production Method Therefor
A composite material including a covalent organic framework (COF) single crystal having a major axis length of larger than 120 μm or a COF polycrystal including a plurality of the single crystals, and at least one heat-storage compound. The heat-storage compound is a compound that generates heat or absorbs heat by adsorption to or desorption from the COF single crystal. Also, a heat dissipation/storage member containing the composite material as a heat storage/dissipation material a COF single crystal having a major axis length of larger than 120 μm, and a method for producing a COF single crystal by crystallizing COF raw material compounds via a solution containing an ionic liquid or an organic salt and an equilibrium adjusting agent to grow a COF single crystal.
A method for producing a capped RNA which is an RNA having the 5′-end modified with a cap, the method including: reacting an activated capping compound represented by
A method for producing a capped RNA which is an RNA having the 5′-end modified with a cap, the method including: reacting an activated capping compound represented by
with a monophosphate RNA having the 5′-end monophosphorylated, where, L represents a leaving group. The activated capping compound is preferably a compound represented by
A method for producing a capped RNA which is an RNA having the 5′-end modified with a cap, the method including: reacting an activated capping compound represented by
with a monophosphate RNA having the 5′-end monophosphorylated, where, L represents a leaving group. The activated capping compound is preferably a compound represented by
C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
92.
LAYERED DOUBLE HYDROXIDE ELECTRIDE AND METHOD FOR PRODUCING SAME
The invention is related to a layered double hydroxide electride which can be produced without high-temperature treatment, and a production method of which cost can be reduced. The layered double hydroxide electride contains electrons between layers and has an electron density of 2.0×1018 cm−3 or more. The method of producing the layered double hydroxide electride includes a step of mixing a starting layered double hydroxide with an electron exchanger for exchanging anions existing between layers of the starting layered double hydroxide for electrons to produce the layered double hydroxide electride.
Each of composite fine particles (10) according to the present invention comprises: an inorganic fine particle (1) which has light wavelength conversion ability; a continuous or discontinuous first coating layer (2) which is formed on a part or the entirety of the surface of the inorganic fine particle (1); a second coating layer (3) which is formed on the first coating layer (2); and a third coating layer which is formed on the second coating layer (3). The second coating layer (2) contains a multidentate organic ligand which is an organic compound that has light absorption in a near-infrared or infrared region, while having at least two coordination positions; the first coating layer (1) is an inorganic compound layer or a metal layer, which contains a coordination metal and a transition metal that is the same as or different from the coordination metal; and the third coating layer (3) is an inorganic compound layer or a metal layer, which contains a coordination metal.
H01L 51/44 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation - Details of devices
94.
ORDERED ALLOY FERROMAGNETIC NANOWIRE STRUCTURE AND METHOD FOR PRODUCING SAME
Provided is an advantageous method for producing an ordered alloy ferromagnetic nanowire structure. This method for producing an ordered alloy ferromagnetic nanowire structure comprises: a step for forming, on a substrate, a nanowire comprising an iron group element and a platinum group element, and having a line width of not more than 100 nm and a line length that is at least twice the line width; and a step for executing a heat treatment on the nanowire to obtain an ordered alloy ferromagnetic nanowire structure in which an ordered alloy ferromagnetic nanowire comprising an ordered alloy of the iron group element and platinum group element is formed on the substrate.
GtG(t)X(t)u(t)t11t1211t21t2211tq1tq2q1tii 1tii 2iqu(t)Ξ0G(∞)XE(t)xtt11t11x11xtt21t21x21xttnn 1tnn 1xnn 1E0x11x21, etc., xnn 11)]; and an output unit 15 for outputting an input matrix when the controllability grammian is maximum, on the basis of an estimated maximization condition.
This device for measuring a characteristic of an object under measurement comprises: a sound wave transmission unit 130 for transmitting a sound wave; a reception unit 140 for receiving an electromagnetic field from an object 200 under measurement that has been generated as a result of the emission of the sound wave onto the object 200 under measurement; a sound wave medium 310 that is between the sound wave transmission unit 130 and object 200 under measurement and is for temporally separating the electromagnetic field from a reverberant electromagnetic field resulting from reverberant vibration of the sound wave transmission unit 130; a despreading unit 160 for using a reference signal relating to the sound wave to despread the electromagnetic field received by the reception unit 140; and a measurement unit 170 for extracting at least one type of characteristic of the object 200 under measurement selected from the group consisting of an electrical characteristic, magnetic characteristic, electromechanical characteristic, and magnetomechanical characteristic on the basis of at least one type of measurement selected from the group consisting of the intensity, phase, and frequency of the despread electromagnetic field.
G01N 22/00 - Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
G01N 24/00 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
97.
NOVEL METHOD FOR PRODUCING COMPOUND, NOVEL COMPOUND, AND METAL CATALYST
One aspect of the present invention is a method for producing a compound represented by general formula (1), the method being characterized by including a step for mixing and reacting ethylene, a compound represented by general formula (2) and a compound represented by general formula (3) to obtain a compound represented by general formula (4). (A1to A4each independently denote an aromatic group. Z1and Z233), Z3denotes an oxygen atom or a sulfur atom, n1to n3 each independently denote 0 or 1, and X denotes a halogen atom.)
The present invention provides a pharmaceutical composition that, with respect to pancreatic cancer and bile duct cancer, suppresses cell proliferation and has an anti-cancer effect. The present invention pertains to: a pharmaceutical composition that contains, as an active ingredient, a substance that reduces the intracellular content of ZIC5 protein and that is used for treatment of pancreatic cancer or bile duct cancer; a pharmaceutical composition that contains an anti-cancer agent other than a substance that reduces the intracellular content of ZIC5 protein; and either of said pharmaceutical compositions, containing an anti-cancer agent other than the substance that reduces the intracellular content of ZIC5 protein.
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
A three-dimensional array device with multiple layers in height direction includes a first two-dimensional array circuit located in a first layer; and a second two-dimensional array circuit located in a second layer adjacent to the first layer and overlapped in a plan view with the first two-dimensional array circuit. Each of the first two-dimensional array circuit and the second two-dimensional array circuit has a first wiring group, an input part that inputs signals to the first wiring group, a second wiring group that intersects the first wiring group and an output part that outputs signals from the second wiring group. The output part in the first two-dimensional array circuit is overlapped in a plan view on the input part in the second two-dimensional array circuit and is connected in a signal transferable manner.
H01L 27/24 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including solid state components for rectifying, amplifying, or switching without a potential-jump barrier or surface barrier
H01L 45/00 - Solid state devices specially adapted for rectifying, amplifying, oscillating, or switching without a potential-jump barrier or surface barrier, e.g. dielectric triodes; Ovshinsky-effect devices; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japan)
Inventor
Abe Hiroshi
Abe Naoko
Inagaki Masahito
Kimura Yasuaki
Hashiya Fumitaka
Li Zhenmin
Nakashima Yuko
Abstract
1423566 represent hydrogen, a C1-10 straight chain or a branched chain alkyl group, etc., and may be the same or different; and "*" represents a bond with nucleotides.)
C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
