The subject invention provides compositions and methods for feeding livestock animals and reducing greenhouse gas emissions from livestock animals. The compositions comprise one or more beneficial microorganisms and/or growth by-products thereof, as well as one or more nutritive mineral components. In certain embodiments, the composition is formulated as a compressed mineral assembly, such as a salt lick or mineral lick, which, when made available to a livestock animal, can be ingested by the livestock animal.
Novel sophorolipid derivatives with enhanced antimicrobial activity have been identified as disinfecting active ingredients. These derivatives are produced through a fermentation of Starmerella bombicola utilizing dextrose and an oleochemical feedstock that is high in oleic acid. A two-step synthetic scheme is used to generate a reactive aldehyde handle and then install nature-derived cationic biodegradable functional groups. These cationic sophorolipid derivatives are purified using ion exchange resins to afford high purity sophorolipid derivative salts for formulation into disinfecting consumer products.
The subject invention provides materials and methods for reducing deleterious atmospheric gases, such as greenhouse gases (GHGs) by enhancing utilization and storage of carbon in plants, as well as increasing the sequestration of carbon in plant and soil matter in the form of degradation-resistant organic polymers.
The topical cosmetic compositions and methods of the subject invention can be used to improve the health and/or appearance of skin by, for example, treating and/or preventing a variety of skin conditions. The invention also provides compositions and methods for enhanced sunless tanning. Biological amphiphilic molecules are used as active components, formulation enhancers and/or delivery vessels for skin active components.
Compositions and methods are provided for producing silage additive composition for producing silage and for controlling pests that infect silage and stored grains. The silage additive composition comprises a microbial inoculant and diatomaceous earth, wherein the microbial inoculant comprises one or more strains of bacteria, wherein the at least one of one or more strains bacteria is capable of producing lactic acid.
A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
A23K 30/15 - Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
A23K 30/18 - Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging using microorganisms or enzymes
C12N 1/00 - Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
Compositions and methods are provided for producing silage additive composition for producing silage and for controlling pests that infect silage and stored grains. The silage additive composition comprises a microbial inoculant and diatomaceous earth, wherein the microbial inoculant comprises one or more strains of bacteria, wherein the at least one of one or more strains bacteria is capable of producing lactic acid.
A23K 30/15 - Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
A23K 30/18 - Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging using microorganisms or enzymes
A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
A23K 20/179 - Colouring agents, e.g. pigmenting or dyeing agents
A23K 10/30 - Animal feeding-stuffs from material of fungal origin, e.g. mushrooms
C12N 1/00 - Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
The subject invention provides improved methods for processing livestock waste, namely, for solid-liquid separation of manure, utilizing microbe-based products. In preferred embodiments, microorganisms and/or microbial surfactants are utilized to improve solid-liquid separation of livestock manure in ways that enhance the value of manure-based fertilizers to farmers and reduces greenhouse gas and other polluting emissions resulting from manure storage.
C05F 17/20 - Preparation of fertilisers characterised by biological or biochemical treatment steps, e.g. composting or fermentation using specific microorganisms or substances, e.g. enzymes, for activating or stimulating the treatment
C05F 3/00 - Fertilisers from human or animal excrements, e.g. manure
The subject invention provides compositions and methods for feeding livestock animals and reducing greenhouse gas emissions from livestock animals. The compositions comprise one or more beneficial microorganisms and/or growth by-products thereof, as well as one or more nutritive mineral components. In certain embodiments, the composition is formulated as a compressed mineral assembly, such as a salt lick or mineral lick, which, when made available to a livestock animal, can be ingested by the livestock animal.
The subject invention provides materials and methods for producing high-HLB sophorolipid- based compositions and/or for increasing the water solubility of sophorolipid compositions. More specifically, the subject invention provides for the production and post-fermentation alteration of SLP molecules, which can be used for formulating a variety of useful compositions.
The subject invention provides materials and methods for producing high-HLB sophorolipid- based compositions and/or for increasing the water solubility of sophorolipid compositions. More specifically, the subject invention provides for the production and post-fermentation alteration of SLP molecules, which can be used for formulating a variety of useful compositions.
A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
C05F 17/20 - Preparation of fertilisers characterised by biological or biochemical treatment steps, e.g. composting or fermentation using specific microorganisms or substances, e.g. enzymes, for activating or stimulating the treatment
A bacterial strain with enhanced biosurfactant-production capabilities is provided, as well as methods of its use in, for example, agriculture, livestock husbandry and environmental protection. In a specific embodiment, the present invention is directed to a bacterial strain that has novel properties for producing a mixture of lipopeptides that is unique to its genus and species. Specifically, the bacterium is a novel strain of Bacillus amyloliquefaciens.
A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
C05F 17/20 - Preparation of fertilisers characterised by biological or biochemical treatment steps, e.g. composting or fermentation using specific microorganisms or substances, e.g. enzymes, for activating or stimulating the treatment
This present invention relates to compositions and methods of enhancing the dispersion of nanoparticles. In certain embodiments, the compositions and methods can be used for enhancing the performance and/or longevity of primers using biochemical-producing microbes and/or byproducts synthesized by the microbes. In certain embodiments, the addition of biosurfactants can enhance the dispersion of pigments and/or other nanoparticles, as well as inhibition of stain or color bleeding through the primer.
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
C09D 5/00 - Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
C09K 8/03 - Specific additives for general use in well-drilling compositions
14.
MATERIALS AND METHODS FOR THE EFFICIENT DISPERSION OF NANOPARTICLES
This present invention relates to compositions and methods of enhancing the dispersion of nanoparticles. In certain embodiments, the compositions and methods can be used for enhancing the performance and/or longevity of primers using biochemical-producing microbes and/or byproducts synthesized by the microbes. In certain embodiments, the addition of biosurfactants can enhance the dispersion of pigments and/or other nanoparticles, as well as inhibition of stain or color bleeding through the primer.
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
C09D 5/00 - Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
The subject invention provides methods and compositions for replacing chemical surfactants for use in a wide variety of industrial applications. More specifically, the subject invention provides for the production of multi-functional biological surface-active compositions having one or more precise functional characteristics based on the desired use.
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
C09K 8/584 - Compositions for enhanced recovery methods for obtaining hydrocarbons, i.e. for improving the mobility of the oil, e.g. displacing fluids characterised by the use of specific surfactants
C12P 1/00 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
C12P 19/44 - Preparation of O-glycosides, e.g. glucosides
The subject invention provides methods and compositions for replacing chemical surfactants for use in a wide variety of industrial applications. More specifically, the subject invention provides for the production of multi-functional biological surface-active compositions having one or more precise functional characteristics based on the desired use.
C12P 7/64 - Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
The subject invention provides materials and methods for producing, isolating, extracting and purifying single-molecule products. The subject invention provides materials and methods for extracting microbial metabolites at a high level of purity, for example, a purity of at least 80% by weight, and preferably at least 95% by weight or more. Specifically, the subject invention provides materials and methods for isolating or extracting biosurfactants and polyketides at a high level of purity. Preferably, the biosurfactant is a sophorolipid (SLP).
The subject invention provides materials and methods for producing, isolating, extracting and purifying single-molecule products. The subject invention provides materials and methods for extracting microbial metabolites at a high level of purity, for example, a purity of at least 80% by weight, and preferably at least 95% by weight or more. Specifically, the subject invention provides materials and methods for isolating or extracting biosurfactants and polyketides at a high level of purity. Preferably, the biosurfactant is a sophorolipid (SLP).
C12P 19/44 - Preparation of O-glycosides, e.g. glucosides
C12P 7/64 - Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
This present invention relates to compositions to improve concrete using biochemical- producing microbes and/or byproducts synthesized by the microbes. The invention also relates to methods for enhancing the performance of the concrete with said microbial strains and/or their byproducts.
C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
C04B 18/14 - Waste materials; Refuse from metallurgical processes
C04B 18/16 - Waste materials; Refuse from building or ceramic industry
C04B 40/00 - Processes, in general, for influencing or modifying the properties of mortars, concrete or artificial stone compositions, e.g. their setting or hardening ability
The subject invention provides compositions and methods for reducing deleterious atmospheric gas emissions produced in livestock animals' digestive systems and/or waste. In preferred embodiments, a composition comprising one or more beneficial microorganisms and/or one or more microbial growth by-products is contacted with the livestock animal's digestive system and/or waste in order to, for example, control methanogenic bacteria therein.
The subject invention provides compositions and methods for reducing deleterious atmospheric gas emissions produced in livestock animals' digestive systems and/or waste. In preferred embodiments, a composition comprising one or more beneficial microorganisms and/or one or more microbial growth by-products is contacted with the livestock animal's digestive system and/or waste in order to, for example, control methanogenic bacteria therein.
The subject invention provides materials and methods for producing and purifying sophorolipids (SLP). More specifically, the subject invention provides materials and methods for the purification of both hydrophobic and hydrophilic SLP molecules to a purity of, for example, at least 80% by weight, preferably at least 95% by weight, without using solvents or centrifugation. Advantageously, the subject invention is suitable for industrial scale production of purified SLP for use in, for example, cleaning products and detergents, and uses safe and environmentally-friendly materials and processes.
The subject invention provides materials and methods for producing and purifying sophorolipids (SLP). More specifically, the subject invention provides materials and methods for the purification of both hydrophobic and hydrophilic SLP molecules to a purity of, for example, at least 80% by weight, preferably at least 95% by weight, without using solvents or centrifugation. Advantageously, the subject invention is suitable for industrial scale production of purified SLP for use in, for example, cleaning products and detergents, and uses safe and environmentally-friendly materials and processes.
C12P 19/44 - Preparation of O-glycosides, e.g. glucosides
C12P 7/64 - Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
24.
REACTOR FOR TWO-STAGE LIQUID-SOLID STATE FERMENTATION OF MICROORGANISMS
In preferred embodiments, the subject invention provides two-vessel fermentation systems for producing microbe-based products comprising fungal mycelia and/or spores, and/or bacterial endospores, wherein the systems comprise both a submerged fermentation vessel and a solid state fermentation (SSF) vessel. Advantageously use of the two phases improves the efficiency of producing microorganisms by catering to the different requirements for biomass and/or vegetative cell accumulation as well as the requirements for mycelial growth and/or sporulation.
In preferred embodiments, the subject invention provides two-vessel fermentation systems for producing microbe-based products comprising fungal mycelia and/or spores, and/or bacterial endospores, wherein the systems comprise both a submerged fermentation vessel and a solid state fermentation (SSF) vessel. Advantageously use of the two phases improves the efficiency of producing microorganisms by catering to the different requirements for biomass and/or vegetative cell accumulation as well as the requirements for mycelial growth and/or sporulation.
The subject invention provides systems, apparatuses and methods for cultivating microorganisms and for producing microbial metabolites on a large scale. Specifically, in certain embodiments, a system comprising three separate, but connected, vessels is provided, wherein a first vessel serves as a feed tank for supplying nutrient medium to a second vessel, said second vessel serving as a submerged fermentation reactor; and wherein a third vessel serves as a collection container into which foam containing microbial growth by-products is transferred from the second vessel.
The subject invention provides systems, apparatuses and methods for cultivating microorganisms and for producing microbial metabolites on a large scale. Specifically, in certain embodiments, a system comprising three separate, but connected, vessels is provided, wherein a first vessel serves as a feed tank for supplying nutrient medium to a second vessel, said second vessel serving as a submerged fermentation reactor; and wherein a third vessel serves as a collection container into which foam containing microbial growth by-products is transferred from the second vessel.
The present invention provides compositions and methods for enhancing the health of a subject by, for example, restoring the subject's gut microbiome, increasing water and electrolyte absorption in the digestive tract, and/or providing a therapeutic substance to the subject. In certain specific embodiments, the present invention can be used for ameliorating the adverse physiological effects that can result from the presence of one or more detrimental microorganisms in a subject's gut. In certain specific embodiments, the present invention can also be used as an enhanced mode of hydration or re-hydration, particularly for subjects suffering from, for example, a condition that causes vomiting and/or diarrhea.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 33/00 - Medicinal preparations containing inorganic active ingredients
A61P 1/08 - Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
The present invention relates to compositions and methods for enhancing the efficacy of drug compounds. The subject invention utilizes an adjuvant composition comprising of one or more microbial-produced biosurfactants and/or isoforms thereof to enhance bioavailability, stability, and localization of the drugs in a subject, to reduce the total dosage that is required, and to prolong the pre-administration stability of the drugs.
Meyerozyma sppMeyerozyma spp. can be cultivated under specially-tailored conditions such that the yeast produces a variety of fatty acid esters. A yeast culture and fermentation compositions are also provided, comprising yeast cells, liquid growth medium, and a high concentration of growth by-products, such as fatty acid esters.
C12P 7/64 - Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
The present invention provides compositions and methods for enhancing the health of a subject by, for example, restoring the subject's gut microbiome, increasing water and electrolyte absorption in the digestive tract, and/or providing a therapeutic substance to the subject. In certain specific embodiments, the present invention can be used for ameliorating the adverse physiological effects that can result from the presence of one or more detrimental microorganisms in a subject's gut. In certain specific embodiments, the present invention can also be used as an enhanced mode of hydration or re-hydration, particularly for subjects suffering from, for example, a condition that causes vomiting and/or diarrhea.
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 33/00 - Medicinal preparations containing inorganic active ingredients
A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
A61K 9/00 - Medicinal preparations characterised by special physical form
A61P 1/08 - Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
The present invention provides materials and methods for treating symptoms of neurological conditions. More specifically, the subject invention provides compositions and methods of their use for treating one or more symptoms and/or comorbidities of a neurological condition such as an infection, a neurodevelopmental disease, and/or a neurodegenerative disease. In preferred embodiments, the composition is administered to the subject via nasal administration.
The present invention relates to compositions and methods for enhancing the efficacy of drug compounds. The subject invention utilizes an adjuvant composition comprising of one or more microbial-produced biosurfactants and/or isoforms thereof to enhance bioavailability, stability, and localization of the drugs in a subject, to reduce the total dosage that is required, and to prolong the pre-administration stability of the drugs.
The present invention provides materials and methods for treating symptoms of neurological conditions. More specifically, the subject invention provides compositions and methods of their use for treating one or more symptoms and/or comorbidities of a neurological condition such as an infection, a neurodevelopmental disease, and/or a neurodegenerative disease. In preferred embodiments, the composition is administered to the subject via nasal administration.
Bacillus amyloliquefaciens Bacillus amyloliquefaciens can be cultivated under specially-tailored conditions such that the bacteria produces both glycolipids resembling mannosylerythritol lipids (MEL), and lipopeptides. A bacterial culture composition is also provided, comprising bacterial cells, liquid growth medium and a high concentration of one or more growth by-products, such as MEL-like glycolipids and/or lipopeptides.
C12P 7/64 - Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
Methods are provided for enhanced production of microbial biosurfactants, the methods comprising co-cultivating Myxococcus xanthus and Pseudomonas chlororaphis. In certain embodiments, the biosurfactants are rhamnolipids or rhamnolipids-like glycolipids. In certain embodiments, other microbial growth by-products are produced, such as organic hydrocarbons including terpenes and/or terpenoids. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, agriculture, oil and gas recovery, and health care.
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
C12P 19/44 - Preparation of O-glycosides, e.g. glucosides
C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
37.
CO-CULTIVATION OF A MYXOBACTERIUM AND ACINETOBACTER FOR ENHANCED PRODUCTION OF EMULSAN
Methods are provided for enhanced production of one or more microbial biopolymers, the methods comprising co-cultivating Stigmatella aurantiaca and Acinetobacter venetianus. In certain embodiments, the one or more biopolymers are emulsan. In certain embodiments, other microbial growth by-products are produced, such as biosurfactants. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, oil and gas recovery, agriculture, and health care.
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
Myxococcus xanthusPseudomonas chlororaphisPseudomonas chlororaphis. In certain embodiments, the biosurfactants are rhamnolipids or rhamnolipids-like glycolipids. In certain embodiments, other microbial growth by-products are produced, such as organic hydrocarbons including terpenes and/or terpenoids. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, agriculture, oil and gas recovery, and health care.
Stigmatella aurantiacaAcinetobacter venetianusAcinetobacter venetianus. In certain embodiments, the one or more biopolymers are emulsan. In certain embodiments, other microbial growth by-products are produced, such as biosurfactants. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, oil and gas recovery, agriculture, and health care.
The subject invention provides materials and methods for preventing, inhibiting or reducing biofilm formation and biofilm infections, in particular, in the respiratory tract of a subject. The invention utilizes growth by-products of beneficial microorganisms to enhance the effectiveness of biocidal substances in the treatment, disruption and/or prevention of biofilms. Advantageously, the subject invention is useful against antibiotic-resistant bacterial strains, such as MRSA, Helicobacter pylori, S. pneumoniae, P. aeruginosa and A. fumigatus.
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
A61K 31/545 - Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula , e.g. cephalosporins, cefaclor, cephalexine
A61K 31/7012 - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A61K 31/7012 - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
A61K 31/545 - Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula , e.g. cephalosporins, cefaclor, cephalexine
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
The subject invention provides stable food products, food additive compositions, and methods for stabilizing and extending the consumable life of food products characterized as dispersions and/or emulsions.
The subject invention provides stable food products, food additive compositions, and methods for stabilizing and extending the consumable life of food products characterized as dispersions and/or emulsions.
The subject invention provides compositions and methods for reducing deleterious atmospheric gases and/or precursors thereof using livestock feed additives and/or supplements. In preferred embodiments, a multi-purpose composition comprising one or more beneficial microorganisms and/or one or more microbial growth by-products is applied to livestock animals' feed and/or to a field or pasture where livestock animals graze. In some embodiments, the composition controls methanogenic bacteria. In some embodiments, the composition enhances carbon sequestration in the field or pasture by promoting plant health and/or growth.
The subject invention provides compositions and methods for reducing deleterious atmospheric gases and/or precursors thereof using livestock feed additives and/or supplements. In preferred embodiments, a multi-purpose composition comprising one or more beneficial microorganisms and/or one or more microbial growth by-products is applied to livestock animals' feed and/or to a field or pasture where livestock animals graze. In some embodiments, the composition controls methanogenic bacteria. In some embodiments, the composition enhances carbon sequestration in the field or pasture by promoting plant health and/or growth.
Myxococcus xanthus Bacillusamyloliquefaciensamyloliquefaciens. In preferred embodiments, co-cultivation is carried out continuously for an indefinite period of time. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, agriculture, oil and gas recovery, and health care.
The subject invention provides microbe-based products and efficient methods of producing them. In specific embodiments, methods are provided for enhanced production of microbial biosurfactants, the methods comprising co-cultivating Myxococcus xanthus and Bacillus amyloliquefaciens. In preferred embodiments, co-cultivation is carried out continuously for an indefinite period of time. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, agriculture, oil and gas recovery, and health care.
The subject invention provides methods for improving the treatment of effluents and waste matter produced during food processing and production. In particular, the subject invention provides methods for remediating fats, oils and greases (FOG), suspended solids, proteins, and other organic matter that are discharged from plants that process, for example, meats, poultry, seafood, dairy and plant-based oils. The methods of the subject invention utilize a customized microbial cocktail comprising facultative anaerobes, in combination with one or more microbial growth by-products, e.g., enzymes and/or biosurfactants, to digest and/or liquefy food processing waste matter.
The subject invention provides methods for improving the treatment of effluents and waste matter produced during food processing and production. In particular, the subject invention provides methods for remediating fats, oils and greases (FOG), suspended solids, proteins, and other organic matter that are discharged from plants that process, for example, meats, poultry, seafood, dairy and plant-based oils. The methods of the subject invention utilize a customized microbial cocktail comprising facultative anaerobes, in combination with one or more microbial growth by-products, e.g., enzymes and/or biosurfactants, to digest and/or liquefy food processing waste matter.
The subject invention provides materials and methods for preventing, inhibiting or reducing biofilm formation and biofilm infections. The invention utilizes growth by-products of beneficial microorganisms to enhance the effectiveness of biocidal substances in the treatment, disruption and/or prevention of biofilms. Advantageously, the subject invention is useful against antibiotic-resistant bacterial strains, such as MRSA and certain strains of Helicobacter pylori.
A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
A61K 31/215 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
A61K 31/661 - Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion
A61K 31/7012 - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
A61K 31/7012 - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
Wickerhamomyces anomalusWickerhamomyces anomalus is cultivated in a specially-tailored nutrient medium and under cultivation conditions such that the yeast unnaturally produces high concentrations of phospholipids that resemble human cardiolipin and/or precursors thereof in structure and/or function. Yeast culture compositions are also provided, comprising yeast cells, growth medium, and high concentrations of phospholipids.
C12P 7/64 - Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
Meyerozyma guilliermondii (Pichia guilliermondiiPseudozyma aphidisPseudozyma aphidis. Yeast culture compositions are also provided, comprising yeast cells, growth medium, and high concentrations of MEL.
The subject invention relates to enhancing for the production of microorganisms and/or their growth by-products by treating and/or preventing bacteriophage contamination of bacterial cultures. Advantageously, the methods can help reduce the likelihood of total and/or partial culture loss through the direct control of bacteriophages and/or prophages that may be present in the culture. In certain embodiments, the method comprise applying an antiviral composition comprising, for example, ribavirin, to the nutrient medium in which a microorganism is being cultivated.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
55.
PRODUCTION AND USE OF YEAST EXTRACT AS A MEDICAL ADJUVANT
The present invention relates to compositions and methods for enhancing bioavailability of health-promoting compounds, such as pharmaceuticals and nutritional supplements. The subject invention utilizes an adjuvant composition comprising yeast extract to enhance bioavailability of health-promoting compounds and to reduce the effective dosage that is required.
The present invention relates to compositions and methods for enhancing bioavailability of health-promoting compounds, such as pharmaceuticals and nutritional supplements. The subject invention utilizes an adjuvant composition comprising yeast extract to enhance bioavailability of health-promoting compounds and to reduce the effective dosage that is required.
BacillusBacillus spp. bacteria, wherein the rate of cell growth is increased through the application of a biostimulant composition comprising peanut hearts to the cultivation medium.
C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
The subject invention provides fuel compositions comprising diesel fuel, water, and one or more biological emulsifying agents, wherein the diesel fuel and water form a water-in-diesel emulsion. Furthermore, methods of improving the stability of water-in-diesel emulsions are provided wherein one or more biological emulsifying agents are added to the emulsion. Preferably, the biological emulsifying agents are biosurfactants and/or bioemulsifiers produced by microorganisms.
Wickerhamomyces anomalusWickerhamomyces anomalus and/or a microbial growth by-product. The composition can be used in place of or in addition to traditional baker's yeast.
The present invention provides compositions and methods for treating a subject infected with a human herpesvirus (HHV). In preferred embodiments, the subject compositions comprise tellimagrandin II, glycyrrhizin, monolaurin, selenium and one or more biological amphiphilic molecules, which, when administered to a subject, can support immune health and suppress and/or disable viral pathogenic agents in the body. The invention can also be used for preventing reactivation of a latent HHV and treating and/or preventing diseases, disorders, conditions and/or comorbidities caused by and/or associated with HHV infection.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A61K 31/22 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
A61K 33/04 - Sulfur, selenium or tellurium; Compounds thereof
A61K 9/00 - Medicinal preparations characterised by special physical form
A61P 31/22 - Antivirals for DNA viruses for herpes viruses
61.
COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING HELICOBACTER PYLORI INFECTIONS
The present invention provides compositions and methods for treating subject infected with Helicobacter pylori. The invention utilizes natural supplement compositions comprising a blend of essential oils, as well as proton-pump inhibitors and biosurfactants. Advantageously, the present invention can lead to simultaneous improvement of diseases, disorders and conditions caused by H. pylori infection, reduction in the occurrence of H. pylori infections, and reduction in the development of antibiotic-resistant strains of the bacteria.
A61K 31/4439 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 36/53 - Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
A61K 36/8962 - Allium, e.g. garden onion, leek, garlic or chives
A61K 31/4439 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 9/00 - Medicinal preparations characterised by special physical form
The subject invention provides compositions and methods for reducing atmospheric methane and/or nitrous oxide emissions using livestock feed additives and/or supplements. In preferred embodiments, a composition comprising a beneficial microorganism and/or a growth by-product thereof is contacted with animal feed and/or drinking water prior to the animal ingesting it. The composition is capable of, for example, controlling methanogenic microorganisms within the animal's digestive system, and thus, reducing the amount of enteric methane emissions produced from the animal and from the animal's waste.
The subject invention provides materials and methods for reducing deleterious atmospheric gases, such as greenhouse gases. In specific embodiments, the reduction in deleterious atmospheric gases is achieved via enhanced vegetative carbon utilization and storage, as well as increased carbon sequestration in soil. In some embodiments, the subject invention can be used for reducing the number of carbon credits used by an operator involved in, e.g., agriculture, livestock production, waste management or other industries. In certain embodiments, the subject invention provides customizable microbe-based products, as well as methods of using these microbe-based products for reduction of greenhouse gases and/or enhanced sequestration of carbon.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
A01N 63/10 - Animals; Substances produced thereby or obtained therefrom
A01N 63/30 - Microbial fungi; Substances produced thereby or obtained therefrom
A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
C09K 17/00 - Soil-conditioning materials or soil-stabilising materials
66.
COMPOSITIONS AND METHODS FOR REDUCING ATMOSPHERIC METHANE AND NITROUS OXIDE EMISSIONS
The subject invention provides compositions and methods for reducing atmospheric methane and/or nitrous oxide emissions using livestock feed additives and/or supplements. In preferred embodiments, a composition comprising a beneficial microorganism and/or a growth by-product thereof is contacted with animal feed and/or drinking water prior to the animal ingesting it. The composition is capable of, for example, controlling methanogenic microorganisms within the animal's digestive system, and thus, reducing the amount of enteric methane emissions produced from the animal and from the animal's waste.
The subject invention provides materials and methods for reducing deleterious atmospheric gases, such as greenhouse gases. In specific embodiments, the reduction in deleterious atmospheric gases is achieved via enhanced vegetative carbon utilization and storage, as well as increased carbon sequestration in soil. In some embodiments, the subject invention can be used for reducing the number of carbon credits used by an operator involved in, e.g., agriculture, livestock production, waste management or other industries. In certain embodiments, the subject invention provides customizable microbe-based products, as well as methods of using these microbe-based products for reduction of greenhouse gases and/or enhanced sequestration of carbon.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
A01N 63/20 - Bacteria; Substances produced thereby or obtained therefrom
The subject invention provides methods and compositions for feeding domesticated animals. In certain embodiments, compositions comprising a microorganism and/or a microbial growth by-products is contacted with an animal's food and/or drinking water. Preferably, the growth by-product is a biosurfactant. Advantageously, the subject invention can promote good health and well-being in a domesticated animal by, for example, enhancing the animal's immune system, promoting digestive health, providing nutrients to the animal and promoting dental/oral cavity health. Furthermore, the subject invention can be used to prolong the shelf life of pet food and prevent contamination of food from deleterious microorganisms.
Starmerella bombicolaStarmerella bombicola yeasts for sophorolipid production, as well as a yeast fermentation product comprising supernatant, yeast cell biomass and other residual growth by-products that result when the sophorolipids are harvested. Methods of using this yeast fermentation product in animal feed, bioremediation, mining and/or bioleaching, agriculture, oil and gas recovery, human health, and many other applications, are also provided.
C09K 8/52 - Compositions for preventing, limiting or eliminating depositions, e.g. for cleaning
C05F 11/08 - Organic fertilisers containing added bacterial cultures, mycelia or the like
A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
The subject invention provides disinfectant compositions and methods of using these compositions for controlling disease in livestock production operations. In one embodiment, a disinfectant composition is provided for controlling disease-causing pathogens in an animal feeding operation (AFO), such as a chicken coop or barn. In preferred embodiments, the composition comprises one or more beneficial microorganisms and/or growth by-products thereof, such as biosurfactants, and is applied inside an enclosure using thermal fogging.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
A01N 63/02 - Substances produced by, or obtained from, microorganisms or animals
A01N 63/04 - Microbial fungi; Substances produced thereby or obtained therefrom
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 25/18 - Vapour or smoke emitting compositions with delayed or sustained release
A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
71.
HYBRID SOLID STATE-SUBMERGED FERMENTATION USING A MATRIX
The subject invention provides methods and systems for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, agriculture, and many other applications. More specifically, the subject invention provides methods and systems for producing microorganisms and/or growth by-products thereof using a hybrid solid state-submerged fermentation method, wherein a matrix comprised of a solid material covered in an alginate coating is formed inside a liquid fermentation vessel. In some embodiments, the solid material is a plurality of natural loofa sponges.
Systems and methods for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, as well as for other applications are provided. More specifically, a moveable all-in-one system for producing microorganisms and/or metabolites is provided. The system can be delivered to a fermentation site in a ready-to-use state, such that on-site fermentation can be initiated in a short period of time.
The subject invention provides microbe-based compositions comprising biologically pure yeasts, and/or one or more microbial growth by-products, such as enzymes. In certain embodiments, the enzymes are phytases. Methods of using these compositions to liberate phosphates from phytic acid-containing organic matter are also provided.
The subject invention provides microbe-based compositions comprising biologically pure yeasts, and/or one or more microbial growth by-products, such as enzymes. In certain embodiments, the enzymes are phytases. Methods of using these compositions to liberate phosphates from phytic acid-containing organic matter are also provided.
Systems and apparatuses for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, as well as for other applications are provided. More specifically, apparatuses comprising two vessels for use in large-scale production of sophorolipids are provided. An apparatus can include a fermentation vessel and a collector vessel connected directly to the fermentation vessel.
C12M 1/00 - Apparatus for enzymology or microbiology
C07H 15/06 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical being a hydroxyalkyl group esterified by a fatty acid
Systems and apparatuses for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, as well as for other applications are provided. More specifically, apparatuses comprising two vessels for use in large-scale production of sophorolipids are provided. An apparatus can include a fermentation vessel and a collector vessel connected directly to the fermentation vessel.
C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
C12M 1/02 - Apparatus for enzymology or microbiology with heat exchange means
C07H 15/06 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical being a hydroxyalkyl group esterified by a fatty acid
The subject invention provides topical therapeutic compositions and methods of their use for enhanced healing of wounds, including bums, and scars of the skin. Specifically, in one embodiment, the subject invention provides materials and methods for reducing the healing time of skin wounds and for reducing the appearance of scars. The subject invention utilizes topical compositions comprising microbial growth by-products and, optionally, a topically-acceptable carrier. In specific embodiments, the microbial growth by-products are biosurfactants.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 35/66 - Microorganisms or materials therefrom
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 31/6615 - Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
The subject invention provides topical therapeutic compositions and methods of their use for enhanced healing of wounds, including bums, and scars of the skin. Specifically, in one embodiment, the subject invention provides materials and methods for reducing the healing time of skin wounds and for reducing the appearance of scars. The subject invention utilizes topical compositions comprising microbial growth by-products and, optionally, a topically-acceptable carrier. In specific embodiments, the microbial growth by-products are biosurfactants.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/6615 - Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 35/66 - Microorganisms or materials therefrom
The subject invention provides methods of producing and preserving stable, standardized reference cultures for use in inoculating fermentation reactors used in research labs and other commercial applications. In specific embodiments, the reference cultures comprise bacterial spores stabilized using, for example, 0.1 to 0.5% phenol, that can be stored for a period of multiple days, weeks, months or even years.
The subject invention provides methods of producing advantageous microbes and/or by products using modified submerged fermentation. A liquid fermentation medium is viscosified to prevent settling of microorganisms in a fermentation reactor. In one embodiment, the microbes are capable of fixing and/or reducing nitrogen. In preferred embodiments, the microbes are anaerobic or microaerophilic bacteria, such as, for example, Clostridium or Rhizobium.
A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 31/166 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
Methods are provided for cultivating fungi for scaled-up production of microbe-based products. Specifically, cultures of fungi, such as, e.g., Pisolithus tinctorius, are grown by aerobic submerged fermentation in liquid medium containing a particulate anchoring carrier to increase mycelial biomass.
Pisolithus tinctoriusPisolithus tinctorius, are grown by aerobic submerged fermentation in liquid medium containing a particulate anchoring carrier to increase mycelial biomass.
The subject invention provides for continuous production of advantageous microbes and/or by-products using a system capable of submerged fermentation, solid-state fermentation, and combinations thereof. In particular, the systems utilize cassettes or other similar containers as vessels for holding a solid substrate inoculated with a microorganism. The cassettes are aligned inside a tank, and the tank can optionally be filled with a liquid nutrient medium. The cassettes with substrate and growing microorganisms are removed from the tank for harvesting the microorganism, and a new, sterilized cassette with substrate can be replaced into the tank.
C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
C12M 1/00 - Apparatus for enzymology or microbiology
C12M 1/06 - Apparatus for enzymology or microbiology with gas introduction means with agitator, e.g. impeller
C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
C12P 1/02 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes by using fungi
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
85.
ENVIRONMENTALLY-FRIENDLY COMPOSITIONS AND METHODS FOR EXTRACTING MINERALS AND METALS FROM ORE
The subject invention provides safe, environmentally-friendly, compositions and methods for extracting minerals and/or metals from ore. More specifically, the subject invention provides for bioleaching using a composition comprising one or more biosurfactant-producing microorganisms and/or microbial growth by-products. In specific embodiments, the composition comprises biosurfactant-producing yeasts and/or their growth by-products.
Embodiments of the present invention provide novel, low-cost fermentation systems and methods of their use. More specifically, the present invention provides biological reactor systems for fermenting a wide variety of, for example, bio level 1 microorganisms with very high cell densities. The reactor systems can be used to grow yeast, fungi and bacteria, as well as growth by-products thereof. In specific embodiments, the reactor systems are used to produce yeast-based compositions. In certain specific embodiments, the reactor systems can be used for the production of Starmerella bombicola yeast compositions.
The present invention provides microbe-based products, as well as methods of their production and use, in oral health compositions. More specifically, the present invention provides materials and methods for enhancing and/or maintaining oral health using topical oral health compositions comprising microbial growth by-products, specifically, biosurfactants.
The subject invention provides compositions and methods for preserving food products. Specifically, the subject compositions and methods can be used to prolong the consumable life of food products, as well as to reduce and/or prevent spoilage and/or contamination by microbial agents. Preferably, the compositions comprise a blend of one or more glycolipids and one or more lipopeptides. Even more preferably, the compositions comprise sophorolipids and surfactin, lichenysin or another lipopeptide biosurfactant.
The present invention provides microbe-based products, as well as methods of their production and use, in oral health compositions. More specifically, the present invention provides materials and methods for enhancing and/or maintaining oral health using topical oral health compositions comprising microbial growth by-products, specifically, biosurfactants.
The subject invention provides compositions and methods for preserving food products. Specifically, the subject compositions and methods can be used to prolong the consumable life of food products, as well as to reduce and/or prevent spoilage and/or contamination by microbial agents. Preferably, the compositions comprise a blend of one or more glycolipids and one or more lipopeptides. Even more preferably, the compositions comprise sophorolipids and surfactin, lichenysin or another lipopeptide biosurfactant.
The subject invention provides safe, environmentally-friendly, compositions and methods for extracting minerals and/or metals from ore. More specifically, the subject invention provides for bioleaching using a composition comprising one or more biosurfactant-producing microorganisms and/or microbial growth by-products. In specific embodiments, the composition comprises biosurfactant-producing yeasts and/or their growth by-products.
The subject invention provides methods of producing advantageous microbes and/or by-products using a modified form of solid-state fermentation, or matrix fermentation. In particular, the methods utilize foodstuff mixed with liquid nutrient medium to produce a three-dimensional scaffold substrate having ample surface area on which the microbes can grow. The methods can be used to cultivate yeasts, fungi and bacteria at high concentrations without susceptibility to total contamination. The subject invention can be used in remote locations and can be transported with ease.
The subject invention provides methods of producing advantageous microbes and/or by-products using a modified form of solid-state fermentation, or matrix fermentation. In particular, the methods utilize foodstuff mixed with liquid nutrient medium to produce a three-dimensional scaffold substrate having ample surface area on which the microbes can grow. The methods can be used to cultivate yeasts, fungi and bacteria at high concentrations without susceptibility to total contamination. The subject invention can be used in remote locations and can be transported with ease.
The present invention provides compositions and methods for the treatment of neurological disorders. In particular, the present invention can be used for treating and/or preventing the symptoms and/or comorbidities of neurodegenerative conditions, diseases or disorders, such as, for example, Alzheimer's and Parkinson's disease.
The subject invention provides materials and methods for improving facial skin, hair and scalp health using cosmetic yeast-based masks. In a specific embodiment, the subject invention provides a yeast-based mask for application to the face, which can improve the health and appearance of thereof. In another specific embodiment, the subject invention provides a yeast-based mask for application to the hair and scalp, which can aid in preventing hair loss, as well as improve the health and appearance of the hair and scalp. Methods of using the yeast-based masks are also provided.
The present invention relates to compositions and methods for enhancing bioavailability of health-promoting substances, such as pharmaceuticals and nutritional supplements. The subject invention utilizes an adjuvant composition comprising one or more microbial-produced biosurfactants and/or isoforms thereof, to enhance bioavailability of health-promoting substances and to reduce the effective dosage that is required.
The subject invention provides materials and methods for improving facial skin, hair and scalp health using cosmetic yeast-based masks. In a specific embodiment, the subject invention provides a yeast-based mask for application to the face, which can improve the health and appearance of thereof. In another specific embodiment, the subject invention provides a yeast-based mask for application to the hair and scalp, which can aid in preventing hair loss, as well as improve the health and appearance of the hair and scalp. Methods of using the yeast-based masks are also provided.
A45D 44/00 - Other cosmetic or toiletry articles, e.g. for hairdressers' rooms
A45D 19/00 - Devices for washing the hair or the scalp; Similar devices for colouring the hair
A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
99.
COMPOSITIONS FOR ENHANCING BIOAVAILABILITY OF PHARMACEUTICALS, SUPPLEMENTS AND INGESTED SUBSTANCES
The present invention relates to compositions and methods for enhancing bioavailability of health-promoting substances, such as pharmaceuticals and nutritional supplements. The subject invention utilizes an adjuvant composition comprising one or more microbial-produced biosurfactants and/or isoforms thereof, to enhance bioavailability of health-promoting substances and to reduce the effective dosage that is required.
The topical cosmetic compositions and methods of the subject invention can be used to treat and/or prevent a variety of skin conditions, including, for example, age spots, acne, scars, body odor, aging-related conditions (e.g., wrinkles, looseness and dryness), and scalp issues (e.g., dandruff, seborrheic dermatitis and hair loss). In preferred embodiments, the compositions according to the subject invention comprise biological amphiphilic molecules produced by microorganisms.
patents
