Abstract

The disclosure relates to organosulfur containing compositions, in particular di-n-propyl thiosulfonate (PTSO) and di-n-propyl thiosulfinate (PTS), di-methyl thiosulfonate, di-phenyl thiosulfonate. Such compositions are useful for as biostimulants for plants. In particular such compositions may result in increased nutrient use efficiency, increased tolerance to abiotic stress, and/or improved quality characteristics. Compositions comprising said organosulfur compounds are also provided for agricultural use.

IPC Classes  ?

• A01N 41/08 - Sulfonic acid halidesSulfonic acidsDerivatives thereof alpha-Hydroxy-sulfonic acidsAmino-sulfonic acidsThiosulfonic acidsDerivatives thereof
• A01G 7/06 - Treatment of growing trees or plants, e.g. for preventing decay of wood, for tingeing flowers or wood, for prolonging the life of plants
• A01N 25/04 - Dispersions or gels
• A01N 37/46 - N-acyl derivatives
• A01N 41/12 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom not containing sulfur-to-oxygen bonds, e.g. polysulfides
• A01P 21/00 - Plant growth regulators

Abstract

The disclosure relates to organosulfur containing compositions, in particular Di-n-butyl thiosulfinate, Di-methyl thiosulfonate, Di-phenyl thiosulfonate, Bis (p-tolyl) thiosulfinate, Di-isopropyl thiosulfinate, Di-benzyl thiosulfinate, Di-benzyl thiosulfonate, S-propyl-4-methylbenzene thiosulfonate, Di-n-propyl thiosulfinate, and Di-n-propyl thiosulfonate. Such compositions are useful for treating infection and reducing or degrading biofilms both in vivo and in vitro. In particular, such compositions are useful in the treatment of biofilm-related disorders, including but not limited to mastitis, digital dermatitis, and chronic wound infections.

IPC Classes  ?

• A61K 31/10 - SulfidesSulfoxidesSulfones
• A01N 31/02 - Acyclic compounds
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61P 31/04 - Antibacterial agents

Abstract

The disclosure relates to organosulfur compounds and compositions comprising same. In particular, the disclosure relates to Bis(4-fluorophenyl) disulfide, Bis(4- chlorophenyl) disulfide, Bis(4-chlorophenyl) thiosulfinate, Bis(4-fluorophenyl) thiosulfinate, Bis(4-chlorophenyl) thiosulfonate, Bis(4-fluorophenyl) thiosulfonate, and Di-isopropyl thiosulfonate. Such compositions are useful for treating microbial infection, in particular bacterial, fungal, rotozoan or algal infection. Compositions comprising said compounds are also provided for cleaning, disinfecting or agricultural use.

IPC Classes  ?

• A61K 31/10 - SulfidesSulfoxidesSulfones
• A61K 31/105 - Persulfides
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61P 31/02 - Local antiseptics
• A61P 31/04 - Antibacterial agents
• A61P 33/00 - Antiparasitic agents
• A61P 41/00 - Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
• A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
• C11D 1/00 - Detergent compositions based essentially on surface-active compoundsUse of these compounds as a detergent

Abstract

Preferred compounds include di-n-propyl disulfide, di-methyl disulfide, di-ethyl disulfide, di-isopropyl disulfide, di-n-butyl-disulfide, di-benzyl disulfide, di-ethyl sulfide, di-n-propyl sulfide, di-isopropyl sulfide, di-n-butyl sulfide, di-phenyl sulfide, di-benzyl sulfide, di-n-propyl trisulfide, di-n-propyl sulfone, di-benzyl thiosulfinate, di-benzyl thiosulfonate, di-isopropyl thiosulfonate, di-n-propyl thiosulfonate (PTSO), and di-n-propyl thiosulfinate (PTS).

IPC Classes  ?

• A61K 31/10 - SulfidesSulfoxidesSulfones
• A61K 31/105 - Persulfides
• A61P 15/14 - Drugs for genital or sexual disordersContraceptives for lactation disorders, e.g. galactorrhoea

Abstract

Preferred compounds include di-n-propyl disulfide, di-methyl disulfide, di-ethyl disulfide, di-isopropyl disulfide, di-n-butyl-disulfide, di-benzyl disulfide, di-ethyl sulfide, di-n-propyl sulfide, di-isopropyl sulfide, di-n-butyl sulfide, di-phenyl sulfide, di-benzyl sulfide, di-n-propyl trisulfide, di-n-propyl sulfone, di-benzyl thiosulfinate, di-benzyl thiosulfonate, di-isopropyl thiosulfonate, di-n-propyl thiosulfonate (PTSO), and di-n-propyl thiosulfinate (PTS).

IPC Classes  ?

• A61K 31/105 - Persulfides
• A61P 15/14 - Drugs for genital or sexual disordersContraceptives for lactation disorders, e.g. galactorrhoea
• A61K 31/10 - SulfidesSulfoxidesSulfones

Goods & Services

Bacterial preparations, other than for medical and veterinary use; bacteriological preparations, other than for medical and veterinary use; biological preparations, other than for medical or veterinary purposes; biological tissue cultures, other than for medical or veterinary purposes. Plant extracts for veterinary use; medicated animal feed; dietetic food and substances adapted for veterinary use; nutritional supplements for animals; food supplements for foodstuffs for animals; medicated supplements for foodstuffs for animals; casein dietary supplements for animals; enzyme dietary supplements for animals; nutritional supplements for veterinary purposes; veterinary preparations; pain relief medication for veterinary purposes; bacterial preparations for veterinary use; biological tissue cultures for veterinary purposes; living cells for veterinary purposes; cultures of microorganisms for veterinary use. Strengthening animal forage; foodstuffs and beverages for animals; foodstuffs for animals containing botanical extracts. Wholesale and retail services relating to bacterial preparations, bacteriological preparations, biological preparations, biological tissue cultures, plant extracts for veterinary use, foodstuffs and nutritional supplements for animals, medicated and dietetic animal feed and dietetic substances for animals, veterinary preparations, pain relief medication for veterinary purposes, bacterial preparations and biological tissue cultures for veterinary use, living cells for veterinary purposes, cultures of microorganisms for veterinary use, strengthening animal forage, foodstuffs and beverages for animals. Testing of raw materials for animal foodstuffs and nutritional supplements for animals; technical consultancy relating to research services in the field of foodstuffs and nutritional supplements for animals; providing information and data relating to veterinary research and developments. Providing information about nutritional supplements and foodstuffs for animals; veterinary services; providing information relating to veterinary services; veterinary information services provided via the internet; analyzing body composition of animals for veterinary purposes.

Goods & Services

Bacterial preparations, other than for medical and veterinary use; bacteriological preparations, other than for medical and veterinary use; biological preparations, other than for medical or veterinary purposes; biological tissue cultures, other than for medical or veterinary purposes Plant extracts, other than essential oils, for veterinary use; medicated animal feed; dietetic food and dietetic pet foods adapted for veterinary use; nutritional supplements for animals; food supplements for foodstuffs for animals; medicated supplements for foodstuffs for animals; casein dietary supplements for animals; enzyme dietary supplements for animals; nutritional supplements for veterinary purposes; pain relief medication for veterinary purposes; bacterial preparations for veterinary use; biological tissue cultures for veterinary purposes; living cells for veterinary purposes; cultures of microorganisms for veterinary use Strengthening animal forage; foodstuffs and beverages for animals; foodstuffs for animals containing botanical extracts Wholesale and retail store services featuring bacterial preparations, bacteriological preparations, biological preparations, biological tissue cultures, plant extracts for veterinary use, foodstuffs and nutritional supplements for animals, medicated and dietetic animal feed and dietetic substances for animals, veterinary preparations, pain relief medication for veterinary purposes, bacterial preparations and biological tissue cultures for veterinary use, living cells for veterinary purposes, cultures of microorganisms for veterinary use, strengthening animal forage, foodstuffs and beverages for animals Testing of raw materials for animal foodstuffs and nutritional supplements for animals; technical consultancy relating to research services in the field of foodstuffs and nutritional supplements for animals; providing information and data relating to veterinary research and developments Providing information about nutritional supplements and foodstuffs for animals; veterinary services; providing information relating to veterinary services; veterinary information services provided via the internet; analyzing body composition of animals for veterinary purposes

Goods & Services

Bacterial preparations, other than for medical and veterinary use; bacteriological preparations, other than for medical and veterinary use; biological preparations, other than for medical or veterinary purposes; biological tissue cultures, other than for medical or veterinary purposes Plant extracts, other than essential oils, for veterinary use; medicated animal feed; dietetic food and dietetic pet foods adapted for veterinary use; nutritional supplements for animals; food supplements for foodstuffs for animals; medicated supplements for foodstuffs for animals; casein dietary supplements for animals; enzyme dietary supplements for animals; nutritional supplements for veterinary purposes; pain relief medication for veterinary purposes; bacterial preparations for veterinary use; biological tissue cultures for veterinary purposes; living cells for veterinary purposes; cultures of microorganisms for veterinary use Strengthening animal forage; foodstuffs and beverages for animals; foodstuffs for animals containing botanical extracts Wholesale and retail store services featuring bacterial preparations, bacteriological preparations, biological preparations, biological tissue cultures, plant extracts for veterinary use, foodstuffs and nutritional supplements for animals, medicated and dietetic animal feed and dietetic substances for animals, veterinary preparations, pain relief medication for veterinary purposes, bacterial preparations and biological tissue cultures for veterinary use, living cells for veterinary purposes, cultures of microorganisms for veterinary use, strengthening animal forage, foodstuffs and beverages for animals. Testing of raw materials for animal foodstuffs and nutritional supplements for animals; technical consultancy relating to research services in the field of foodstuffs and nutritional supplements for animals; providing information and data relating to veterinary research and developments Providing information about nutritional supplements and foodstuffs for animals; veterinary services; providing information relating to veterinary services; veterinary information services provided via the internet; analyzing body composition of animals for veterinary purposes

Abstract

The disclosure relates to organosulfur containing compositions, in particular di-n- propyl thiosulfonate (PTSO) and di-n-propyl thiosulfinate (PTS), di-methyl thiosulfonate, di-phenyl thiosulfonate. Such compositions are useful for as biostimulants for plants. In particular such compositions may result in increased nutrient use efficiency, increased tolerance to abiotic stress, and/or improved quality characteristics. Compositions comprising said organosulfur compounds are also provided for agricultural use.

IPC Classes  ?

• A01N 41/08 - Sulfonic acid halidesSulfonic acidsDerivatives thereof alpha-Hydroxy-sulfonic acidsAmino-sulfonic acidsThiosulfonic acidsDerivatives thereof
• A01N 41/12 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom not containing sulfur-to-oxygen bonds, e.g. polysulfides
• A01N 65/42 - Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
• A01P 21/00 - Plant growth regulators
• A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
• A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
• A01N 25/04 - Dispersions or gels
• A01N 37/44 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio-analogue of a carboxylic group, e.g. amino-carboxylic acids
• A01N 37/46 - N-acyl derivatives
• C05G 1/00 - Mixtures of fertilisers covered individually by different subclasses of class
• C05G 3/50 - SurfactantsEmulsifiers
• C05G 3/60 - Biocides or preservatives, e.g. disinfectants, pesticides or herbicidesPest repellants or attractants

Abstract

The disclosure relates to organosulfur containing compositions, in particular di-n- propyl thiosulfonate (PTSO) and di-n-propyl thiosulfinate (PTS), di-methyl thiosulfonate, di-phenyl thiosulfonate. Such compositions are useful for as biostimulants for plants. In particular such compositions may result in increased nutrient use efficiency, increased tolerance to abiotic stress, and/or improved quality characteristics. Compositions comprising said organosulfur compounds are also provided for agricultural use.

IPC Classes  ?

• A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
• A01N 25/04 - Dispersions or gels
• A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
• A01N 37/44 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio-analogue of a carboxylic group, e.g. amino-carboxylic acids
• A01N 37/46 - N-acyl derivatives
• A01N 41/08 - Sulfonic acid halidesSulfonic acidsDerivatives thereof alpha-Hydroxy-sulfonic acidsAmino-sulfonic acidsThiosulfonic acidsDerivatives thereof
• A01N 41/12 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom not containing sulfur-to-oxygen bonds, e.g. polysulfides
• A01N 65/42 - Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
• A01P 21/00 - Plant growth regulators
• C05G 1/00 - Mixtures of fertilisers covered individually by different subclasses of class
• C05G 3/50 - SurfactantsEmulsifiers
• C05G 3/60 - Biocides or preservatives, e.g. disinfectants, pesticides or herbicidesPest repellants or attractants

Abstract

The disclosure relates to organosulfur containing compositions, in particular Di-n-butyl thiosulfinate, Di-methyl thiosulfonate, Di -phenyl thiosulfonate, Bis (p-tolyl) thiosulfinate, Di-isopropyl thiosulfinate, Di-benzyl thiosulfinate, Di-benzyl thiosulfonate, S-propyl-4-methylbenzene thiosulfonate, Di -n-propyl thiosulfinate, and Di-n-propyl thiosulfonate. Such compositions are useful for treating infection and reducing or degrading biofilms both in vivo and in vitro. In particular, such compositions are useful in the treatment of biofilm-related disorders, including but not limited to mastitis, digital dermatitis, and chronic wound infections.

IPC Classes  ?

• A61K 31/10 - SulfidesSulfoxidesSulfones
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61P 31/02 - Local antiseptics
• A61P 31/04 - Antibacterial agents
• A61P 33/00 - Antiparasitic agents
• A61P 41/00 - Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
• A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests

Abstract

The disclosure relates to thiosulfur containing compositions, in particular propyl-propane thiosulfonate (PTSO) and propyl-propane-thiosulfinate (PTS). Such compositions are useful for treating infection and reducing or degrading biofilms both in vivo and in vitro. In particular, such compositions are useful in the treatment of biofilm-related disorders, including but not limited to mastitis, digital dermatitis, and chronic wound infections.

IPC Classes  ?

• A61K 31/255 - Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
• A01N 41/08 - Sulfonic acid halidesSulfonic acidsDerivatives thereof alpha-Hydroxy-sulfonic acidsAmino-sulfonic acidsThiosulfonic acidsDerivatives thereof
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
• A61P 31/02 - Local antiseptics
• C07C 381/04 - Thiosulfonates
• A61K 31/095 - Sulfur, selenium or tellurium compounds, e.g. thiols
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
• A23K 20/105 - Aliphatic or alicyclic compounds
• A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

Goods & Services

Bacterial preparations, other than for medical and veterinary use; bacteriological preparations, other than for medical and veterinary use; biological preparations, other than for medical or veterinary purposes; biological tissue cultures, other than for medical or veterinary purposes. Plant extracts for veterinary use; medicated animal feed; dietetic food and substances adapted for veterinary use; nutritional supplements for animals; food supplements for foodstuffs for animals; medicated supplements for foodstuffs for animals; casein dietary supplements for animals; enzyme dietary supplements for animals; nutritional supplements for veterinary purposes; veterinary preparations; pain relief medication for veterinary purposes; bacterial preparations for veterinary use; biological tissue cultures for veterinary purposes; living cells for veterinary purposes; cultures of microorganisms for veterinary use. Strengthening animal forage; foodstuffs and beverages for animals; foodstuffs for animals containing botanical extracts. Wholesale and retail services relating to bacterial preparations, bacteriological preparations, biological preparations, biological tissue cultures, plant extracts for veterinary use, foodstuffs and nutritional supplements for animals, medicated and dietetic animal feed and dietetic substances for animals, veterinary preparations, pain relief medication for veterinary purposes, bacterial preparations and biological tissue cultures for veterinary use, living cells for veterinary purposes, cultures of microorganisms for veterinary use, strengthening animal forage, foodstuffs and beverages for animals. Testing of raw materials for animal foodstuffs and nutritional supplements for animals; technical consultancy relating to research services in the field of foodstuffs and nutritional supplements for animals; providing information and data relating to veterinary research and developments. Providing information about nutritional supplements and foodstuffs for animals; veterinary services; providing information relating to veterinary services; veterinary information services provided via the internet; analyzing body composition of animals for veterinary purposes.

Goods & Services

Bacterial preparations, other than for medical and veterinary use; bacteriological preparations, other than for medical and veterinary use; biological preparations, other than for medical or veterinary purposes; biological tissue cultures, other than for medical or veterinary purposes. Plant extracts for veterinary use; medicated animal feed; dietetic food and substances adapted for veterinary use; nutritional supplements for animals; food supplements for foodstuffs for animals; medicated supplements for foodstuffs for animals; casein dietary supplements for animals; enzyme dietary supplements for animals; nutritional supplements for veterinary purposes; veterinary preparations; pain relief medication for veterinary purposes; bacterial preparations for veterinary use; biological tissue cultures for veterinary purposes; living cells for veterinary purposes; cultures of microorganisms for veterinary use. Strengthening animal forage; foodstuffs and beverages for animals; foodstuffs for animals containing botanical extracts. Wholesale and retail services relating to bacterial preparations, bacteriological preparations, biological preparations, biological tissue cultures, plant extracts for veterinary use, foodstuffs and nutritional supplements for animals, medicated and dietetic animal feed and dietetic substances for animals, veterinary preparations, pain relief medication for veterinary purposes, bacterial preparations and biological tissue cultures for veterinary use, living cells for veterinary purposes, cultures of microorganisms for veterinary use, strengthening animal forage, foodstuffs and beverages for animals. Testing of raw materials for animal foodstuffs and nutritional supplements for animals; technical consultancy relating to research services in the field of foodstuffs and nutritional supplements for animals; providing information and data relating to veterinary research and developments. Providing information about nutritional supplements and foodstuffs for animals; veterinary services; providing information relating to veterinary services; veterinary information services provided via the internet; analyzing body composition of animals for veterinary purposes.