Abstract

The invention relates to the use of an organic transistor with a permeable base (14) as a memory or as a long-term photodetector. The transistor is designed as a vertical transistor and has an emitter (11), a collector (12), an organic semiconductor (13) and a base (14). In a switched-off state, illumination with light to which the organic semiconductor is sensitive can be used to write information into the transistor, which information can, in a second operating state, then be read out on the basis of the shift in the threshold voltage of the transistor with respect to the nominal threshold voltage of the transistor. When further features of the transfer characteristic curve are evaluated, information about the illumination intensity and/or illumination duration can also be determined. In a third operating state, the transistor can be reset to an unilluminated state and the information stored by the illumination can be erased again.

IPC Classes  ?

• H10K 10/43 - Bipolar transistors, e.g. organic bipolar junction transistors [OBJT]
• H10F 30/24 - Individual radiation-sensitive semiconductor devices in which radiation controls the flow of current through the devices, e.g. photodetectors the devices having potential barriers, e.g. phototransistors the devices being sensitive to infrared, visible or ultraviolet radiation the devices having only two potential barriers, e.g. bipolar phototransistors
• H10K 10/46 - Field-effect transistors, e.g. organic thin-film transistors [OTFT]
• H10K 39/32 - Organic image sensors

Abstract

The invention relates to an optical device for machining a sample by means of interfering laser beams. The optical device has at least one beam splitter, at least one interference lens associated with the beam splitter, and at least one beam-shaping lens. The beam splitter is arranged in such a way that a laser beam incident on the optical device can be split into at least two partial beams along an interference axis perpendicular to the optical axis. The interference lens is arranged downstream of the beam splitter in such a way that the partial beams can be deflected relative to one another in such a way that the partial beams interfere with one another in an interference region so that the sample can be machined in the interference region. The beam-shaping lens is arranged in such a way that the laser beam can be focused with respect to a focussing axis arranged perpendicularly to the interference axis and to the optical axis. The beam-shaping lens is arranged upstream of the interference lens. The invention also relates to an optical system and to the use of the optical device.

IPC Classes  ?

• B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing

Abstract

According to various aspects, a signal feed-through (100) has: a ceramic feed-through element (102) in the form of a hollow cylinder, so that a passage opening (108) in the ceramic feed-through element (102) extends from a first side of the hollow cylinder to a second side of the hollow cylinder opposite the first side, wherein the ceramic feed-through element (102) is designed for feeding a signal conductor (104), the diameter of which is smaller than a diameter of the passage opening (108), through the passage opening (108); a metal sleeve (106) which is physically connected to the ceramic feed-through element (102) by means of a solder material (114), wherein the metal sleeve (106) is designed to be connected to the signal conductor; wherein: the ceramic feed-through element has a surface structuring (110, 112) in a portion of a surface of the ceramic feed-through element facing the metal sleeve and/or the metal sleeve (106) has a surface structuring (110, 112) on a surface of the metal sleeve opposite the ceramic feed-through element in order to reduce residual thermal stresses at a boundary surface between the ceramic feed-through element and the solder material.

IPC Classes  ?

• H01B 17/30 - Sealing
• H01B 17/38 - Fittings, e.g. capsFastenings therefor

Abstract

The present invention relates to an agricultural implement (1) having at least one drive device (2), at least one working unit (3), at least one sensing device (4) for sensing living beings in a working path of the working unit (3), and at least one evaluation unit for evaluating the signal from the sensor, wherein the sensing device is fastened to the drive device (2) and/or to the working unit (3), and the sensing device (4) is in contact with the ground via at least one rotatable unit (5), and the sensing device (4) has at least one sensor (6) for scanning the working path of the working unit (3). The sensor (6) is designed in such a way that the working path is completely scanned before the working unit (3) travels over the scanned working path.

IPC Classes  ?

• A01D 75/20 - Devices for protecting men or animals

Abstract

The present invention relates to an attachment element for electric conductors of a cable (1) enclosed by an electric insulation, said electric conductors being exposed at one cable end, wherein the attachment element is formed from at least one receptacle (2) and a rotary element (4) and/or a sliding element (3) and/or a switch element. Furthermore, the receptacle (2) has at least one guide opening (5) in which at least one cable (1) can be guided and wherein a guide channel (6) adjoins the guide opening (5). Furthermore, the at least one guidable cable (1) can be force-locked and form-locked in the receptacle (2) as a result of a deformation of the cable (1) caused by the rotary element (4) being rotated and/or as a result of a deformation of the receptacle (2) caused by the sliding element (3) being displaced and/or as a result of a deformation of the receptacle (2) caused by the switch element being actuated.

IPC Classes  ?

• H02G 1/14 - Methods or apparatus specially adapted for installing, maintaining, repairing, or dismantling electric cables or lines for joining or terminating cables
• H01R 4/22 - End caps, i.e. caps of insulating or conductive material for covering or maintaining connections between wires entering the cap from the same end
• H02G 15/04 - Cable-end sealings

Abstract

A speaker and a method are disclosed, where the speaker comprises a rotary actuator comprising a wound laminate. The laminate comprises a first layer and a second layer each comprising or consisting of a dielectric elastomer, a first electrode disposed between the first layer and the second layer in direct contact therewith. The laminate also comprises a second metal layer disposed between and electrically conductively connected to a first sub-layer of the first electrode and a second sub-layer of the first electrode. The laminate also comprises a second electrode disposed on a side of the first layer distal from the first electrode and in direct contact with the first layer; a third electrode disposed on a side of the second layer distal from the first electrode and in direct contact with the second layer. The laminate also comprises a first metal layer electrically conductively connected to the third electrode.

IPC Classes  ?

• H04R 7/12 - Non-planar diaphragms or cones
• H04R 19/02 - Loudspeakers

Abstract

According to various embodiments, an electric cell (100a, 100b) comprises: a base layer (102); a first electrode (104l), in which a first edge of the base layer (102) is embedded; a second electrode (104r), in which a second edge of the base layer (102) opposite the first edge is embedded; and a separator (106) with which the first electrode (104l) and the second electrode (104r) are coated.

IPC Classes  ?

• H01M 10/04 - Construction or manufacture in general
• H01M 6/02 - Details
• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms
• H01M 50/429 - Natural polymers
• H01M 50/44 - Fibrous material
• H01M 50/46 - Separators, membranes or diaphragms characterised by their combination with electrodes
• H01M 50/449 - Separators, membranes or diaphragms characterised by the material having a layered structure
• H01M 50/474 - Spacing elements inside cells other than separators, membranes or diaphragmsManufacturing processes thereof characterised by their position inside the cells
• H01M 50/48 - Spacing elements inside cells other than separators, membranes or diaphragmsManufacturing processes thereof characterised by the material
• H01G 11/08 - Structural combinations, e.g. assembly or connection, of hybrid or EDL capacitors with other electric components, at least one hybrid or EDL capacitor being the main component
• H01G 11/26 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features
• H01G 11/52 - Separators
• H01G 11/84 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof

Abstract

According to various embodiments, a leaf structure (10) of organic origin is used to form a separator (106) of an electric cell (100a, 100b).

IPC Classes  ?

• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms
• H01M 50/454 - Separators, membranes or diaphragms characterised by the material having a layered structure comprising a non-fibrous layer and a fibrous layer superimposed on one another
• H01M 50/429 - Natural polymers
• H01M 50/491 - Porosity
• H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells
• H01M 12/08 - Hybrid cellsManufacture thereof composed of a half-cell of a fuel-cell type and a half-cell of the secondary-cell type
• H01G 11/52 - Separators
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals

Abstract

The present invention provides a method of identifying an amino acid position of a DNA modifying enzyme for insertion of a heterologous DNA binding domain (DBD), the method comprising the steps of providing a library of DNA modifying enzymes, wherein the members of the library comprise heterologous amino acid sequence insertions throughout the DNA modifying enzyme; identifying those DNA modifying enzymes of the library that have DNA modifying activity; and identifying the position of the insertion in those DNA modifying enzymes identified in the previous step. The present invention further pertains to methods of producing DNA modifying enzymes comprising an inserted heterologous DBD, to methods for modifying a nucleic acid sequence in a cell, and to methods for evolving a DNA binding domain on desired target sequences. Further provided are nucleic acid sequences encoding such DNA modifying enzymes and DNA binding domains, respective vectors and host cells.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• A61K 38/00 - Medicinal preparations containing peptides
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

Abstract

in vitroin vitro population of porcine pseudo-islets obtained by treatment with a Rho/ROCK inhibitor, wherein greater than 30% of the population exhibit a defined size with an average diameter of 30-350 μm and a standard deviation (SD) of 10 or less. The invention also relates to the pseudo-islet population for use in the treatment of diabetes, preferably type 1 diabetes, in a subject, wherein the pseudo-islet population is transplanted to the subject.

IPC Classes  ?

• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

Abstract

The present invention provides a method of identifying an amino acid position of a DNA modifying enzyme for insertion of a heterologous DNA binding domain (DBD), the method comprising the steps of providing a library of DNA modifying enzymes, wherein the members of the library comprise heterologous amino acid sequence insertions throughout the DNA modifying enzyme; identifying those DNA modifying enzymes of the library that have DNA modifying activity; and identifying the position of the insertion in those DNA modifying enzymes identified in the previous step. The present invention further pertains to methods of producing DNA modifying enzymes comprising an inserted heterologous DBD, to methods for modifying a nucleic acid sequence in a cell, and to methods for evolving a DNA binding domain on desired target sequences. Further provided are nucleic acid sequences encoding such DNA modifying enzymes and DNA binding domains, respective vectors and host cells.

IPC Classes  ?

• C12N 9/22 - Ribonucleases
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12N 15/90 - Stable introduction of foreign DNA into chromosome

Abstract

The invention relates to an alkali-sulfur battery, and to a use thereof. The alkali-sulfur secondary battery contains or consists of: a cathode which contains or consists of a sulfur source, an electrically conductive carbon material and an alkali-metal-ion-conductive solid electrolyte; an anode; and an organic electrolyte which contains or consists of an organic ether and a conductive salt. The organic electrolyte contacts the cathode and the anode and is characterized in that, at a temperature in the range of 20°C to 100°C, it has a solubility for sulfur-containing components of the cathode that lies in the range of ≤ 10 mmol of sulfur atoms per liter of organic electrolyte. The alkali-sulfur secondary battery according to the invention has a very high specific energy density and, at the same time, high durability. In fact, a specific energy density is achieved which significantly exceeds the specific energy density of all previously known alkali-sulfur secondary batteries.

IPC Classes  ?

• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates

Abstract

The invention relates to a method for analysing a quasi-periodic biological signal which comprises measured values for a measurement interval. According to the invention, the method comprises the following steps: (a) determining from the quasi-periodic biological signal a first observation window, which has a first period, and a second observation window, which has a second period, the first observation window and the second observation window being within the measurement interval and the second period being shorter than the first period; (b) classifying the measured values using the first observation window by a first model to obtain a first classification result and classifying the measured values using the second observation window by a second model to obtain a second classification result, the first model and the second model each being based on an artificial neural network; and (c) interpreting the first classification result and the second classification result by determining the relevance of one or more of the measured values to generate the first classification result and the relevance of one or more of the measured values to generate the second classification result.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/346 - Analysis of electrocardiograms

Abstract

The invention relates to a photo detector (100) comprising: a first layer (110) comprising a semiconducting material of a first type, preferably of an n-type; a second layer (150) comprising a semiconducting material of a second type which differs from the first type, preferably of a p-type; a two-dimensional structure (130) in physical contact with the first layer (110) and the second layer (150), wherein the two-dimensional structure (130) has one or more plies of a two-dimensional material; a drain electrode (160) in contact with the first layer (110); a gate electrode (170) in contact with the second layer (150); and a source electrode (140) in contact with the two-dimensional structure (130), wherein the photo detector is designed to emit a sensor signal, wherein the sensor signal is based on a photo-induced source-gate current between the gate electrode (170) and the source electrode (140) when electromagnetic radiation is absorbed in the first layer (110), and/or the sensor signal is based on a photo-induced source-drain current between the drain electrode (160) and the source electrode (140) when the electromagnetic radiation is absorbed in the second layer (150).

IPC Classes  ?

• H01L 31/112 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by field-effect operation, e.g. junction field-effect photo- transistor
• H01L 31/101 - Devices sensitive to infrared, visible or ultraviolet radiation
• H01L 31/028 - Inorganic materials including, apart from doping material or other impurities, only elements of Group IV of the Periodic System
• H01L 31/0352 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their shape or by the shapes, relative sizes or disposition of the semiconductor regions

Abstract

A computing system (100) and a corresponding method (200) are disclosed, wherein the computing system (100) comprises a processor (102) which is designed: to receive a computing request (106), which comprises a computing task (108) and associated conditions (110), the conditions (110) comprising an energy consumption condition and a latency condition and/or an accuracy condition; to select at least one computing unit from a plurality of computing units (104(n = 1 to N)), each computing unit of the plurality of computing units having a computing architecture, at least one computing unit of the plurality of computing units having a computing architecture different from at least one other computing unit of the plurality of computing units (104(n = 1 to N)), and each computing unit (104(n)) being assigned computing architecture information (112(n)) containing information about properties of the n computing unit with respect to the energy consumption and at least one latency and/or accuracy in an execution of a computing task (108); wherein the at least one computing unit is selected using the computing architecture information (112(n = 1 to N)).

IPC Classes  ?

• G06F 9/50 - Allocation of resources, e.g. of the central processing unit [CPU]

Abstract

A panel (100) is proposed, the panel (100) comprising: a top panel outer face (110o) and a bottom panel outer face (110u); a three-dimensional spacer structure (120) situated between the two outer faces (110o, 110u), the three-dimensional spacer structure (120) comprising a plurality of three-dimensional structure elements (121), the plurality of three-dimensional structure elements (121) being shaped and situated relative to one another so as to form at least one insertion channel (130) into which an insert element (140) can be inserted; and an insert element (140) that is inserted at least in part into the at least one insertion channel (130), the insert element (140) comprising at least one fastening portion (141) for the fastening of a fastening element (145) to the panel via the insert element (140) and via the three-dimensional spacer structure (120).

IPC Classes  ?

• F16B 5/01 - Joining sheets or plates to one another or to strips or bars parallel to them by means of fastening elements specially adapted for honeycomb panels
• E04F 13/12 - Coverings or linings, e.g. for walls or ceilings composed of covering or lining elementsSub-structures thereforFastening means therefor composed of a plurality of similar covering or lining elements of metal
• F16B 9/00 - Connections of rods or tubular parts to flat surfaces at an angle
• F16B 5/06 - Joining sheets or plates to one another or to strips or bars parallel to them by means of clamps or clips

Abstract

The invention relates to a lightweight panel system and to a method for fastening a screw-in element in a lightweight panel. The lightweight panel system (400) comprises: a lightweight panel (100) having a first cover plate (120) and a second cover plate (120), a support core (110), and a three-dimensional wire structure element (200) for holding a screw-in element (300) therein, the support core (110) and the three-dimensional wire structure element (200) being arranged between the first cover plate (120) and the second cover plate (120), the support core (110) and the three-dimensional wire structure element (200) being connected to one another, and/or the support core (110) and the three-dimensional wire structure element (200) being connected to the first cover plate (120) and to the second cover plate (120); and a screw-in element (300) which corresponds to the three-dimensional wire structure element (200) and which is designed to plastically deform at least sections of the three-dimensional wire structure element (200) when the screw-in element (300) is screwed into the three-dimensional wire structure element (200).

IPC Classes  ?

• F16B 5/01 - Joining sheets or plates to one another or to strips or bars parallel to them by means of fastening elements specially adapted for honeycomb panels
• F16B 37/12 - Nuts or like thread-engaging members with thread-engaging surfaces formed by inserted coil-springs, discs, or the likeIndependent pieces of wound wire used as nutsThreaded inserts for holes
• B29C 65/56 - Joining of preformed partsApparatus therefor using mechanical means

Abstract

nNMeML TT TL TT f TT MnMnNTL nn eMM) between the input sound level and output sound level of the masking sound from the two curves; h. calculating the distortion filter from the control deviation. The invention also relates to a system for the psychoacoustic calibration of an audio playback system which is configured to carry out the method according to the invention.

IPC Classes  ?

• H04R 29/00 - Monitoring arrangementsTesting arrangements

Abstract

In various embodiments, a process for producing a metallized graphene fibre structure is provided, said process comprising: providing a leaf structure from a plant leaf, where the provided leaf structure is a leaf skeleton; pretreating the leaf structure by means of a treatment medium to alter the electrical properties of the leaf structure in order to form a pretreated leaf structure; treating the pretreated leaf structure by means of a metal ion solution such that the leaf structure has a metallic coating; and heating the coated leaf structure in such a way that the leaf skeleton is converted to graphene, in order to form the metallized graphene fibre structure.

IPC Classes  ?

• C01B 32/184 - Preparation
• H01B 1/02 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of metals or alloys
• H01B 1/22 - Conductive material dispersed in non-conductive organic material the conductive material comprising metals or alloys

Abstract

Different embodiments relate to a method for producing a flexible biodegradable electrode, having the steps of: (a) providing a leaf structure made of a plant leaf, said leaf structure having a plurality of leaf veins; (b) pre-treating the leaf structure using a treatment agent in order to change the electric properties of the leaf structure in order to form a pre-treated leaf structure; and (c) treating the pre-treated leaf structure with an at least metal-ion solution such that each leaf vein of the pre-treated leaf structure is coated with at least one metal layer; or having the steps of: (a) providing a leaf structure made of a plant leaf, said leaf structure having a plurality of leaf veins; (b) optionally pre-treating the leaf structure using a corona treatment in order to form a pre-treated leaf structure; and (c) treating the optionally pre-treated leaf structure with a composition having chelated metal microparticles of at least one metal such that each leaf vein of the leaf structure is coated with at least one metal layer in order to form the flexible biodegradable electrode for organic electronic components.

IPC Classes  ?

• H01B 1/02 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of metals or alloys
• H01B 1/22 - Conductive material dispersed in non-conductive organic material the conductive material comprising metals or alloys

Abstract

Different embodiments relate to a method for producing a flexible biodegradable substrate, having the steps of: providing (100) a leaf structure (10) made of a plant leaf, said leaf structure having a plurality of leaf veins; and treating (200) the leaf structure with a polymer solution (20) in order to change the mechanical properties of the leaf structure such that each leaf vein of the leaf structure is coated with a polymer layer made of the polymer solution in order to form a coated leaf structure (14, 18) as a support for organic electronic components, wherein one or more openings pass through the polymer layer, each of the openings being arranged between two of the leaf veins.

IPC Classes  ?

• H10K 30/80 - Constructional details
• H10K 77/10 - Substrates, e.g. flexible substrates

Abstract

The invention relates to salts of 4-hydroxybicyclo[3.3.1]non-3-ene-2,9-dione derivatives. A compound of general formula (IA) or (IB) is provided, where A represents -C=C- and n is 0 or 1; R1is selected from among the group consisting of isoprenyl, geranyl, benzyl and methyl; R2is selected from among the group consisting of allyl, isoprenyl and methyl; R3is selected from among the group consisting of allyl, isoprenyl, benzyl and methyl; R411611611611611616 alkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, and unsubstituted or substituted heteroaryl; R5represents methyl or isoprenyl, and R6 represents methyl or isoprenyl.

IPC Classes  ?

• C09B 23/14 - Styryl dyes
• C09B 23/10 - Methine or polymethine dyes, e.g. cyanine dyes characterised by the methine chain containing an even number of CH groups
• C09B 23/06 - Methine or polymethine dyes, e.g. cyanine dyes characterised by the methine chain containing an odd number of CH groups three CH groups, e.g. carbocyanines
• C07D 201/00 - Preparation, separation, purification, or stabilisation of unsubstituted lactams
• A61P 35/00 - Antineoplastic agents
• C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 309/04 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
• C07D 309/32 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
• C07F 5/02 - Boron compounds

Abstract

2mm- and m is 0, 1 or 2; n is 1, 2 or 3; M is a metal ion; R1is selected from the group consisting of isoprenyl, geranyl, benzyl and methyl; R2is selected from the group consisting of allyl, isoprenyl and methyl; R3is selected from the group consisting of allyl, isoprenyl, benzyl and methyl; R411621621616-alkinyl, cycloalkyl, unsubstituted or R7-substituted aryl and unsubstituted or R7-substituted heteroaryl; R5is methyl or isoprenyl; R6is methyl or isoprenyl; and R711611611616-halogenalkyl and aryl.

IPC Classes  ?

• C07C 49/92 - Ketonic chelates
• C07D 333/22 - Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 31/04 - Antibacterial agents
• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings

Abstract

The invention relates to 4-hydroxybicyclo[3.3.1]non-3-ene-2,9-dione derivatives. Here, a compound of general formula (I) is provided, where X is selected from the group consisting of a group of general formula (G1), a group of general formula (G2) and a group of general formula (G3); R1is selected from the group consisting of isoprenyl, geranyl, benzyl and methyl; R2is selected from the group consisting of allyl, isoprenyl and methyl; R3is selected from the group consisting of allyl, isoprenyl, benzyl and methyl; R411611611616 alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkylene, and aryl which is unsubstituted or is substituted with R9; R5is methyl or isoprenyl; R6122 are in each case C; R7is -OH or =O; R8is -OH or =O; and R91161611611611611616 alkyl; with the proviso that, if R722 identifies a double bond and, if R722 identifies a single bond; and that, if R811 identifies a double bond and, if R811 identifies a single bond, and R7and R8 are not simultaneously -OH; and with the additional proviso that, if X is a group of general formula (G1) or a group of general formula (G2), the dashed line to X identifies a single bond and, if X is a group of general formula (G3), the dashed line to X identifies a double bond.

IPC Classes  ?

• C07C 235/82 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
• A61K 31/16 - Amides, e.g. hydroxamic acids
• A61P 31/04 - Antibacterial agents
• A61P 35/00 - Antineoplastic agents

Abstract

22, and if the bond between X and Y is a double bond, then X represents C and Y represents CH; R1is selected from the group that consists of isoprenyl, geranyl, benzyl and methyl; R2is selected from the group that consists of allyl, isoprenyl and methyl; R3is selected from the group that consists of allyl, isoprenyl, benzyl and methyl; R411616-alkyl, cycloalkyl, unsubstituted aryl or aryl substituted with R7and unsubstitited heteroaryl or heteroaryl substituted with R7; R5is methyl or isoprenyl; R6is methyl or isoprenyl and R711611611616-halogenalkyl and aryl.

IPC Classes  ?

• C07D 309/32 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
• C07D 309/38 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
• C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
• A61P 35/00 - Antineoplastic agents
• A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring

Abstract

The invention relates to 4-hydroxybicyclo[3.3.1]non-3-ene-2,9-dione derivatives. According to the invention, the derivatives comprise a compound of the general formula (I), wherein A represents -C=C- or -C=C-C=C-; R1is selected from the group consisting of isoprenyl, geranyl, benzyl and methyl; R2is selected from the group consisting of allyl, isoprenyl and methyl; R3is selected from the group consisting of allyl, isoprenyl, benzyl and methyl; R4is selected from the group consisting of unsubstituted or substituted cycloalkyl, unsubstituted or substituted heterocycloalkyl, unsubstituted or substituted aryl and unsubstituted or substituted heteroaryl, wherein the group -C(O)-A-R4forms a fluorophore entity; R5is methyl or isoprenyl; and R6 is methyl or isoprenyl.

IPC Classes  ?

• C09B 23/14 - Styryl dyes
• C09B 23/10 - Methine or polymethine dyes, e.g. cyanine dyes characterised by the methine chain containing an even number of CH groups
• C09B 23/06 - Methine or polymethine dyes, e.g. cyanine dyes characterised by the methine chain containing an odd number of CH groups three CH groups, e.g. carbocyanines
• C07D 201/00 - Preparation, separation, purification, or stabilisation of unsubstituted lactams
• A61P 35/00 - Antineoplastic agents
• C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 309/04 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
• C07D 309/32 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

Abstract

The invention relates to a cell structure which comprises material layers (2), wherein: in each case two material layers (2) resting one on top of the other comprise, in alternation, composite portions (4) which are joined together, and loose portions (6) which are not joined together; the cell structure is formed by expansion in the W direction (8); cells (12, 12') form in the expanded loose portions (6); the size of the cells (12, 12') differs in a cell-size ratio (V) in the W direction (8) and/or in the L direction (10); and a T direction perpendicular to the W-L plane determines a height (T) of the cell structure. According to the invention, a first region (20) of a uniform honeycomb structure has smaller cells (12), and a second region (24) has larger cells (12'). The regions (20, 24) are separated from one another by a transition region (22) which is provided between the smaller cells (12) and the larger cells (12'). The invention also relates to a cell support core for use in a sandwich structure.

IPC Classes  ?

• B31D 3/02 - Making articles of cellular structure, e.g. insulating board honeycombed structures