The invention disclosed herein is directed to a porous wound healing foam composition that is made from an extracellular matrix of a mammal, method of making, and method of using.
Large-area medical graft devices comprise at least two sheets of extracellular matrix material (ECM). The sheets of ECM have overlapping regions that are compressed together during a non-drying process, and other overlapping regions that are not compressed together. The compressed overlapping regions have a more collapsed matrix structure, while the non-compressed overlapping regions having a more open matrix structure. The sheets of ECM can have a stacked orientation to create a desired thickness, or a staggered orientation to create a desired surface area, or combinations of both orientations.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Scaffold composed of biologically-derived tissue, tissue matter and tissue matrix for management, repair, reconstruction, and restoration of tissues; scaffold composed of biologically-derived tissue matrix for the management, repair, reconstruction and restoration of tissue in a patient
4.
Extracellular matrix sheet devices with improved mechanical properties and method of making
Described are devices and associated methods of producing extracellular matrix (ECM) sheet devices with strengthened mechanical properties due to the selective retention of muscle tissue layers during processing.
Large-area medical graft devices comprise at least two sheets of extracellular matrix material (ECM). The sheets of ECM have overlapping regions that are compressed together during a non-drying process, and other overlapping regions that are not compressed together. The compressed overlapping regions have a more collapsed matrix structure, while the non-compressed overlapping regions having a more open matrix structure. The sheets of ECM can have a stacked orientation to create a desired thickness, or a staggered orientation to create a desired surface area, or combinations of both orientations.
Implantable pouch devices for encasing a cardiac implantable electronic device (CIED) or other medical device are formed from one or more bioresorbable sheets of material comprising an extracellular matrix (ECM) for maintaining and supporting a healing environment. Each bioresorbable sheet may be a medical graft assembly which comprises at least first and second sheets of ECM material layered together such that the epithelial basement membrane sides face outward.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biological tissue in powdered form for medical use; naturally occurring bio-scaffold in powdered form for repair or restoration of tissue in a patient; wound dressings; medical dressings, coverings and applicators; pre-filled syringes for medical purposes. Scaffold composed of non-living material in powdered form for repair or restoration of tissue in a patient; medical devices for treating wounds; scaffold composed of non-living material in powdered form for applying to a wound in a syringe with a flexible tip; disposable syringes; injection syringes; medical syringes; parts and fitting for syringes.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biological tissue in powdered form for medical use; naturally occurring bio-scaffold in powdered form for repair or restoration of tissue in a patient; wound dressings Scaffold composed of non-living material in powdered form for repair or restoration of tissue in a patient; medical devices for treating wounds; scaffold composed of non-living material in powdered form for applying to a wound in a syringe with a flexible tip
9.
Porous foams derived from extracellular matrix, porous foam ECM medical devices, and methods of use and making thereof
The invention disclosed herein is directed to a porous wound healing foam composition that is made from an extracellular matrix of a mammal, method of making, and method of using.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Scaffold composed of biologically-derived tissue, tissue matter and tissue matrix for management, repair, reconstruction, and restoration of tissues; scaffold composed of biologically-derived tissue matrix for the management, repair, reconstruction and restoration of tissue in a patient
(2) Medical and surgical devices, namely, non-living extra cellular matter, matrix scaffold and implantable scaffolds comprised of natural, non-living materials for management, repair, reconstruction, and restoration of tissues
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biologically-derived tissue, tissue matter and tissue matrix for management, repair, reconstruction, and restoration of tissues; scaffold composed of biologically-derived tissue matrix for the management, repair, reconstruction and restoration of tissue in a patient. Medical and surgical devices, namely, non-living extra cellular matter, matrix scaffold and implantable scaffolds comprised of natural, non-living materials for management, repair, reconstruction, and restoration of tissues.
12.
Particulate tissue graft with components of differing density and methods of making and using the same
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biological tissue in powdered form for medical use; naturally occurring bio-scaffold in powdered form for repair or restoration of tissue in a patient. Scaffold composed of non-living material in powdered form for repair or restoration of tissue in a patient.
15.
EXTRACELLULAR MATRIX COMPOSITIONS WITH BACTERICIDAL OR BACTERIOSTATIC CHARACTERISTICS USEFUL FOR PROTECTING AND TREATING PATIENTS WITH BACTERIAL INFECTIONS
Described is a formulation and method for reducing and treating bacterial infections in humans and animals with digested or non-digested extracellular matrix materials derived from non-epithelial and epithelial tissues.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biological tissue in powdered form for medical use; naturally occurring bio-scaffold in powdered form for repair or restoration of tissue in a patient Scaffold composed of non-living material in powdered form for repair or restoration of tissue in a patient
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Scaffold composed of biological tissue in powdered form for medical use; naturally occurring bio-scaffold in powdered form for repair or restoration of tissue in a patient.
(2) Scaffold composed of non-living material in powdered form for repair or restoration of tissue in a patient
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Wound dressings; surgical implants comprised of living tissues; Biological tissue cultures for medical and veterinary purposes, namely, implantable scaffold composed of biologically-derived tissue in the form of sheets, gels, foam and in powdered form, comprised of extra cellular matrix for repair and restoration of human and animal tissues; Biological tissue cultures for medical and veterinary purposes, namely, surgical implants comprising living tissues and biomaterials in the form of scaffolds for use in wound healing, surgery as well as for regeneration of tissue and organs; Biological tissue cultures for medical and veterinary purposes, namely, implants comprising biologically-derived extracellular tissue matrix in sheet, gels, foam, and powered form; Biological tissue cultures used as a surgical repair medium, namely, surgical implants comprising biologically-derived material for use in surgery and to repair and restore human and animal tissue
(2) Surgical implants comprised of artificial materials; Prosthetic tissues for repair and restoration of human and animal tissues, namely, non-living extra-cellular matrix scaffold and implantable scaffold comprised of non-living extra cellular matter; Prosthetic tissues for repair and restoration of human and animal tissues, namely, surgical implants comprising non-living implant materials in the form of scaffolds and implantable sheets, gels, foam and in powdered form for use in wound healing, and surgery, and for regeneration of tissue and organs
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Wound dressings; surgical implants comprised of living tissues; Biological tissue cultures for medical and veterinary purposes, namely, implantable scaffold composed of biologically-derived tissue in the form of sheets, gels, foam and in powdered form, comprised of extra cellular matrix for repair and restoration of human and animal tissues; Biological tissue cultures for medical and veterinary purposes, namely, surgical implants comprising living tissues and biomaterials in the form of scaffolds for use in wound healing, surgery as well as for regeneration of tissue and organs; Biological tissue cultures for medical and veterinary purposes, namely, implants comprising biologically-derived extracellular tissue matrix in sheet, gels, foam, and powered form; Biological tissue cultures used as a surgical repair medium, namely, surgical implants comprising biologically-derived material for use in surgery and to repair and restore human and animal tissue
(2) Surgical implants comprised of artificial materials; Prosthetic tissues for repair and restoration of human and animal tissues, namely, non-living extra-cellular matrix scaffold and implantable scaffold comprised of non-living extra cellular matter; Prosthetic tissues for repair and restoration of human and animal tissues, namely, surgical implants comprising non-living implant materials in the form of scaffolds and implantable sheets, gels, foam and in powdered form for use in wound healing, and surgery, and for regeneration of tissue and organs
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Wound dressings; surgical implants comprised of living tissues; Biological tissue cultures for medical and veterinary purposes, namely, implantable scaffold composed of biologically-derived tissue in the form of sheets, gels, foam and in powdered form, comprised of extra cellular matrix for repair and restoration of human and animal tissues; Biological tissue cultures for medical and veterinary purposes, namely, surgical implants comprising living tissues and biomaterials in the form of scaffolds for use in wound healing, surgery as well as for regeneration of tissue and organs; Biological tissue cultures for medical and veterinary purposes, namely, implants comprising biologically-derived extracellular tissue matrix in sheet, gels, foam, and powered form; Biological tissue cultures used as a surgical repair medium, namely, surgical implants comprising biologically-derived material for use in surgery and to repair and restore human and animal tissue
(2) Surgical implants comprised of artificial materials; Prosthetic tissues for repair and restoration of human and animal tissues, namely, non-living extra-cellular matrix scaffold and implantable scaffold comprised of non-living extra cellular matter; Prosthetic tissues for repair and restoration of human and animal tissues, namely, surgical implants comprising non-living implant materials in the form of scaffolds and implantable sheets, gels, foam and in powdered form for use in wound healing, and surgery, and for regeneration of tissue and organs
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
materials for dressings; surgical implants comprised of living tissues; Implantable scaffold composed of biologically-derived tissue in the form of sheets of extra cellular matrix for repair and restoration of human and animal tissues; surgical implants comprising living tissues and biomaterials in the form of scaffolds for use in wound healing, surgery as well as for regeneration of tissue and organs; medical preparations for the regeneration of tissue; implants comprising biologically-derived extracellular tissue matrix in the form of implantable sheets; Surgical repair medium, namely, surgical implants comprising biologically-derived material for use in surgery and to repair and restore human and animal tissue. Surgical apparatus and instruments; Medical and veterinary apparatus and instruments; therapeutic and prosthetic articles and devices for implantation composed of artificial or synthetic materials; surgical implants comprised of artificial materials; Implantable scaffold comprised of non-living extra cellular matter for repair and restoration of human and animal tissues; implantable scaffold composed of non-living implant materials for repair or restoration of tissue; surgical implants comprising non-living implant materials in the form of scaffolds and implantable sheets for use in wound healing, and surgery, as well as for regeneration of tissue and organs; Surgical and wound treating equipment.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
materials for dressings; surgical implants comprised of living tissues; Implantable scaffold composed of biologically-derived tissue in the form of sheets of extra cellular matrix for repair and restoration of human and animal tissues; surgical implants comprising living tissues and biomaterials in the form of scaffolds for use in wound healing, surgery as well as for regeneration of tissue and organs; medical preparations for the regeneration of tissue; implants comprising biologically-derived extracellular tissue matrix in the form of implantable sheets; Surgical repair medium, namely, surgical implants comprising biologically-derived material for use in surgery and to repair and restore human and animal tissue. Surgical apparatus and instruments; Medical, and veterinary apparatus and instruments; therapeutic and prosthetic articles and devices for implantation composed of artificial or synthetic materials; surgical implants comprised of artificial materials; Implantable scaffold comprised of non-living extra cellular matter for repair and restoration of human and animal tissues; implantable scaffold composed of non-living implant materials for repair or restoration of tissue; surgical implants comprising non-living implant materials in the form of scaffolds and implantable sheets for use in wound healing, and surgery, as well as for regeneration of tissue and organs; surgical and wound treating equipment.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceuticals; Medical preparations; Veterinary preparations; sanitary preparations for medical purposes; materials for dressings; surgical implants comprised of living tissues; Scaffold composed of biologically-derived tissue for management, repair and restoration of tissues; scaffold composed of biologically-derived tissue for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations; scaffold composed of biological tissue, in the form of sheets, gels, foam and in powdered form, comprised of extracellular matrix for repair and restoration of human and animal tissues; surgical implants comprising living tissues and biomaterials in the form of scaffolds and scaffold material in sheet, gels, foam, and powered form for use in wound healing, surgery as well as for constructive remodeling or regeneration of tissue and organs; medical preparations for the constructive remodeling or regeneration of tissue; implants comprising extracellular tissue matrix in the form of implantable sheets, gels, foam and powder; Surgical repair medium, namely, surgical implants comprising biological material for use in surgery and to repair and restore human and animal tissue. Surgical apparatus and instruments; Medical, and veterinary apparatus and instruments; therapeutic and prosthetic articles and devices for implantation composed of artificial or synthetic materials; surgical implants comprised of artificial materials; Medical devices, namely, non-living extracellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for management, repair and restoration of tissues; medical devices, namely, non-living extracellular matrix scaffold and implantable scaffolds all comprised of natural, non-living materials for repair and restoration of tissue; medical devices, namely, non-living extracellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for repair and restoration of tissue, namely, for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations; scaffold comprised of non-living extracellular matter in the form of sheets, gels, foam and in powdered form for repair and restoration of human and animal tissues; Scaffold composed of non-living implants for repair or restoration of tissue; surgical implants comprising non-living implants in the form of scaffolds, implantable sheets, gels, foam and in powdered form for use in wound healing, and surgery, as well as for constructive remodeling or regeneration of tissue and organs; surgical and wound treating equipment.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceuticals; Medical preparations; Veterinary preparations; sanitary preparations for medical purposes; materials for dressings; surgical implants comprised of living tissues; Scaffold composed of biologically-derived tissue for management, repair and restoration of tissues; scaffold composed of biologically-derived tissue for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations; scaffold composed of biological tissue, in the form of sheets, gels, foam and in powdered form, comprised of extracellular matrix for repair and restoration of human and animal tissues; surgical implants comprising living tissues and biomaterials in the form of scaffolds and scaffold material in sheet, gels, foam, and powered form for use in wound healing, surgery as well as for constructive remodeling or regeneration of tissue and organs; medical preparations for the constructive remodeling or regeneration of tissue; implants comprising extracellular tissue matrix in the form of implantable sheets, gels, foam and powder; Surgical repair medium, namely, surgical implants comprising biological material for use in surgery and to repair and restore human and animal tissue. Surgical apparatus and instruments; Medical, and veterinary apparatus and instruments; therapeutic and prosthetic articles and devices for implantation composed of artificial or synthetic materials; surgical implants comprised of artificial materials; Medical devices, namely, non-living extracellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for management, repair and restoration of tissues; medical devices, namely, non-living extracellular matrix scaffold and implantable scaffolds all comprised of natural, non-living materials for repair and restoration of tissue; medical devices, namely, non-living extracellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for repair and restoration of tissue, namely, for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations; scaffold comprised of non-living extracellular matter in the form of sheets, gels, foam and in powdered form for repair and restoration of human and animal tissues; Scaffold composed of non-living implants for repair or restoration of tissue; surgical implants comprising non-living implants in the form of scaffolds, implantable sheets, gels, foam and in powdered form for use in wound healing, and surgery, as well as for constructive remodeling or regeneration of tissue and organs; surgical and wound treating equipment.
25.
Variable density tissue graft composition and methods of making and using the same
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce homeostasis at an anatomical site.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61D 1/00 - Surgical instruments for veterinary use
A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
A61B 17/00 - Surgical instruments, devices or methods
A61L 31/00 - Materials for other surgical articles
A61L 15/40 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof
A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
A61L 27/58 - Materials at least partially resorbable by the body
28.
Methods of manufacturing bioactive gels from extracellular matrix material
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
extra cellular matrix scaffold; scaffold composed of biologically-derived tissue matrix for management, repair and restoration of tissues; scaffold composed of biologically-derived tissue matrix for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations; Wound dressings; Materials for dressing wounds. Medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds; medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds all comprised of natural, non-living materials for repair and restoration of tissue; medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for repair and restoration of tissue, namely, for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations; Suture and wound closing materials and products.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Extra cellular matrix scaffold; scaffold composed of biologically-derived tissue matrix for management, repair and restoration of tissues; scaffold composed of biologically-derived tissue matrix for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations
(2) Medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds; medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds all comprised of natural, non-living materials for repair and restoration of tissue; medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for repair and restoration of tissue, namely, for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61D 1/00 - Surgical instruments for veterinary use
A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
A61B 17/00 - Surgical instruments, devices or methods
A61L 31/00 - Materials for other surgical articles
A61L 15/40 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof
A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
A61L 27/58 - Materials at least partially resorbable by the body
33.
POROUS FOAMS DERIVED FROM EXTRACELLULAR MATRIX, POROUS FOAM ECM MEDICAL DEVICES, AND METHODS OF USE AND MAKING THEREOF
The invention disclosed herein is directed to a porous wound healing foam composition that is made from an extracellular matrix of a mammal, method of making, and method of using.
The invention disclosed herein is directed to a porous wound healing foam composition that is made from an extracellular matrix of a mammal, method of making, and method of using.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Implantable scaffold composed of biologically-derived tissue in the form of sheets of extra cellular matrix for repair and restoration of human and animal tissues; surgical implants comprising living tissues and biomaterials in the form of scaffolds for use in wound healing, surgery as well as for regeneration of tissue and organs; medical preparations for the regeneration of tissue; implants comprising biologically-derived extracellular tissue matrix in the form of implantable sheets; Surgical repair medium, namely, surgical implants comprising biologically-derived material for use in surgery and to repair and restore human and animal tissue Implantable scaffold comprised of non-living extra cellular matter for repair and restoration of human and animal tissues; implantable scaffold composed of non-living implant materials for repair or restoration of tissue; surgical implants comprising non-living implant materials in the form of scaffolds and implantable sheets for use in wound healing, and surgery, as well as for regeneration of tissue and organs
36.
Methods of manufacturing bioactive gels from extracellular matrix material
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biologically-derived tissue matrix for management, repair and restoration of tissues; scaffold composed of biologically-derived tissue matrix for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations Medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for management, repair and restoration of tissues; medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds all comprised of natural, non-living materials for repair and restoration of tissue; medical devices, namely, non-living extra cellular matrix scaffold and implantable scaffolds comprised of natural, non-living materials for repair and restoration of tissue, namely, for the management of wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunnel/undermined wounds, surgical wounds, trauma wounds, burns, skin tears, abrasions, and lacerations
38.
Particulate tissue graft with components of differing density and methods of making and using the same
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A61B 17/00 - Surgical instruments, devices or methods
A61L 31/00 - Materials for other surgical articles
A61L 15/40 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof
A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
A61L 27/58 - Materials at least partially resorbable by the body
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61D 1/00 - Surgical instruments for veterinary use
A61L 15/40 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof
A61L 31/00 - Materials for other surgical articles
A61B 17/00 - Surgical instruments, devices or methods
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
A61L 15/40 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof
A61L 31/00 - Materials for other surgical articles
50.
Particulate tissue graft with components of differing density and methods of making and using the same
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biological tissue in powdered form for medical use; naturally occurring bio-scaffold in powdered form for repair or restoration of tissue in a patient Scaffold composed of non-living material in powdered form for repair or restoration of tissue in a patient
53.
PARTICULATE TISSUE GRAFT WITH COMPONENTS OF DIFFERING DENSITY AND METHODS OF MAKING AND USING THE SAME
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
An implant for implanting at the site of an anatomical tissue in a human patient, comprises a plurality of bioresorbable composite particles, each of said composite particles comprising a portion derived from each of two extracellular matrix materials, wherein one of said two extracellular matrix materials comprises a density that is greater than the density of the other of said two extracellular matrix materials.
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Scaffold composed of biological tissue, namely, naturally occurring bio-scaffold for repair or restoration of tissue in a patient.
(2) Scaffold comprised of synthetic matter for repair or restoration of tissue in a patient.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Scaffold composed of biological tissue, namely, naturally occurring bio-scaffold for repair or restoration of tissue in a patient; Surgical tissues. Scaffold comprised of synthetic matter for repair or restoration of tissue in a patient; Surgical, medical and veterinary apparatus and instruments; orthopedic articles; suture materials; artificial skin for surgical purposes. Medical services; Veterinary services; Hygienic and beauty care for human beings or animals.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Pharmaceutical and veterinary preparations of biological origin, for tissue reconstruction; surgical implants; dressings; surgical tissues; scaffold material for medical use and for repair or restoration of tissue.
(2) Surgical, medical and veterinary apparatus and instruments namely, extracellular matrix ("ECM") devices to repair and remodel damaged tissues and organs; artificial skin for surgical purposes; scaffold material for repair or restoration of tissue; scaffold composed of non-living implants for repair and restoration of tissue
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Scaffold composed of biological tissue for medical use, namely, naturally occurring bio-scaffold for repair or restoration of tissue for veterinary use Scaffold material composed of non-living implants for repair or restoration of tissue for veterinary use
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; orthopedic articles; suture materials. Medical services; veterinary services; hygienic and beauty care for human beings or animals; agriculture, horticulture and forestry services.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
SCAFFOLD COMPOSED OF BIOLOGICAL TISSUE, NAMELY, NATURALLY OCCURRING BIO-SCAFFOLD FOR REPAIR OR RESTORATION OF TISSUE IN A PATIENT SCAFFOLD COMPRISED OF SYNTHETIC MATTER FOR REPAIR OR RESTORATION OF TISSUE IN A PATIENT
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
scaffold material composed of biological tissue, namely, naturally occurring bio-scaffold material derived from porcine bladders for repair or restoration of tissue in a patient, none of the foregoing for orthopedic, cranio-facial, maxillary, and dental applications in the human field
Scaffold material composed of non-living implants for repair or restoration of tissue in a patient, none of the foregoing for orthopedic, cranio-facial, maxillary, and dental applications in the human field
