Abstract

An imaging apparatus may include a light source emitting linear light, a light reflector configured to reflect the linear light incident from the light source unit, a first filter configured to filter the linear light reflected from the light reflector, a light transmission reflector configured to reflect the linear light passing through the first filter toward an object and transmit light incident from the object, a second filter configured to filter the light that has passed through the light transmission reflector after being incident from the object, and a camera configured to capture the light passing through the second filter.

IPC Classes  ?

• G01N 21/33 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
• G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
• G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
• G01N 21/47 - Scattering, i.e. diffuse reflection

Abstract

A method using deep learning includes: sampling video to generate a video clip composed sampled frames, and generating a set of differential images between the sampled frames; extracting a first feature map with spatial features and a second feature map with temporal features by applying the sampled frames and the set of differential images to a learned deep learning-based behavior recognition model, and generating a spatio-temporal combined feature map for each sampled frame by combining the first feature map and the second feature map; calculating a bi-directional exponential moving average using the spatio-temporal combined feature map, and then adjusting weights of the spatio-temporal combined feature maps; generating a temporal relationship importance map by applying the video clip and performing late fusion by applying the weight-adjusted spatio-temporal combined feature map and the temporal relationship importance map to the learned deep learning-based behavior recognition model, and classifying the behavior.

IPC Classes  ?

• G06V 40/20 - Movements or behaviour, e.g. gesture recognition
• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
• G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
• G06V 10/80 - Fusion, i.e. combining data from various sources at the sensor level, preprocessing level, feature extraction level or classification level
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks

Abstract

A D2D scheduling method in a UAV-based IoT network includes: (a) acquiring a geographical map for all transmission links of a D2D network within a network coverage area; (b) applying the geographical map to a sparse convolution model to extract a feature map; (c) defining the feature map for a time slot t as a state St, and then inputting the feature map to actor and critic networks of a reinforcement learning-based scheduling policy learning model, respectively, and selecting a scheduling decision At for the D2D transmission link based on a scheduling output of the actor network and a greedy strategy; and (d) transmitting the scheduling decision At to the D2D network and then receiving reward when the scheduling decision At is applied by the D2D network, wherein the reward is calculated as a total achievable transmission rate.

IPC Classes  ?

• H04W 72/40 - Resource management for direct mode communication, e.g. D2D or sidelink
• G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
• G06V 20/17 - Terrestrial scenes taken from planes or by drones
• G16Y 10/75 - Information technologyCommunication
• G16Y 40/35 - Management of things, i.e. controlling in accordance with a policy or in order to achieve specified objectives
• H04L 5/00 - Arrangements affording multiple use of the transmission path
• H04N 23/61 - Control of cameras or camera modules based on recognised objects
• H04W 72/0446 - Resources in time domain, e.g. slots or frames

Abstract

A cooling apparatus for a power module including a plurality of cooling modules provided to be in contact with each of both surfaces of the power module, in which the cooling module includes a manifold cover provided with a plurality of guide walls extending in a first direction in a state of being spaced apart from each other and a pin plate having one surface being in contact with the power module and having a plurality of pins extending in a second direction crossing the first direction formed on the other surface thereof.

IPC Classes  ?

• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

Abstract

An operation method of performing a neural network operation of fully homomorphic encrypted data is provided. The operation method includes: receiving data for performing the neural network operation and receiving a parameter for generating an approximation polynomial corresponding to the neural network operation; obtaining layer information corresponding to layers of a neural network model, the layer information based on the data; determining importances of the layers, respectively, wherein the determining of the importances is based on the parameter and the layer information; generating an approximation polynomial approximating the neural network operation for each of the layers, wherein the generating is based on the layer importance; and generating an operation result by performing the neural network operation based on the approximation polynomial, wherein the parameter includes a computation time condition that the neural network operation must satisfy.

IPC Classes  ?

• G06N 3/048 - Activation functions
• G06F 11/07 - Responding to the occurrence of a fault, e.g. fault tolerance
• G06F 17/17 - Function evaluation by approximation methods, e.g. interpolation or extrapolation, smoothing or least mean square method

Abstract

In a method of manufacturing a packaging unit, a material layer is stacked for forming the semiconductor device on one surface of a substrate, a semiconductor device is formed by performing a semiconductor process on the material layer, a flow channel through which a cooling fluid flows is formed on the other surface of the substrate to enable direct cooling of the semiconductor device using the cooling fluid, a packaging block is disposed at a position spaced apart from the substrate for packaging of the semiconductor device, and an electrode placed on the packaging block is electrically connected to the semiconductor device, and a heat sink unit having a flow path forming portion in which a flow path communicating with the flow channel of the substrate is formed is arranged below the packaging block, and the substrate is combined with the heat sink unit.

IPC Classes  ?

• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids
• H01L 21/48 - Manufacture or treatment of parts, e.g. containers, prior to assembly of the devices, using processes not provided for in a single one of the groups or
• H01L 23/367 - Cooling facilitated by shape of device
• H01L 23/433 - Auxiliary members characterised by their shape, e.g. pistons

Abstract

A processor-implemented method includes receiving data for performing a neural network operation of homomorphic encrypted data and a parameter for generating an approximate polynomial corresponding to the neural network operation, obtaining layer information corresponding to each of a plurality of layers configuring a neural network based on the data, determining layer importance corresponding to each of the plurality of layers, based on the parameter and the layer information, generating an approximate polynomial approximating the neural network operation for each of the plurality of layers, based on the layer importance, and generating an operation result by performing the neural network operation based on the approximate polynomial.

IPC Classes  ?

• G06N 3/08 - Learning methods
• G06N 3/04 - Architecture, e.g. interconnection topology
• H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols

Abstract

Disclosed are a method for estimating the moving direction of a front vehicle using radar and an apparatus thereof. The method for estimating the moving direction of a front vehicle using radar comprises the steps of: (a) acquiring a radar detection result and then signal-processing the radar detection result to acquire front vehicle information; (b) converting the front vehicle information into point cloud data in a 2D space; (c) converting the point cloud data into an image by preprocessing the point cloud data; and (d) outputting progress direction and angle information of a front vehicle by applying the converted image to a trained deep learning model.

IPC Classes  ?

• B60W 30/16 - Control of distance between vehicles, e.g. keeping a distance to preceding vehicle
• B60W 30/095 - Predicting travel path or likelihood of collision

Abstract

Disclosed is a method for manufacturing an organic optoelectronic device, the method including: coating a second layer composition on a mediator; and forming a second layer of thin film on a first layer by moving the second layer composition coated on the mediator onto the first layer, wherein the second layer composition contains a donor and an acceptor and the acceptor includes a non-fullerene compound.

IPC Classes  ?

• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof

Abstract

Disclosed are a method and an apparatus for extracting a target on the basis of an FMCW radar. The method for extracting a target on the basis of an FMCW radar comprises the steps of: (a) transmitting a radar transmission signal, the radar transmission signal being a signal to which binary phase shift keying (BPSK) modulation has been performed on the basis of a first binary code; (b) obtaining a radar reception signal reflected by a target; (c) generating a ghost target signal by multiplying the reception signal by a second binary code; and (d) extracting an actual target signal by removing the ghost target signal from the reception signal.

IPC Classes  ?

• G01S 7/35 - Details of non-pulse systems
• G01S 13/50 - Systems of measurement based on relative movement of target
• G01S 13/536 - Discriminating between fixed and moving objects or between objects moving at different speeds using transmission of continuous unmodulated waves, amplitude-, frequency-, or phase-modulated waves
• G01S 13/931 - Radar or analogous systems, specially adapted for specific applications for anti-collision purposes of land vehicles

Abstract

Provided is a cascaded FMCW radar, and more particularly, to a cascaded FMCW radar with a synchronized PLL. The cascaded FMCW radar includes a crystal oscillator generating a reference frequency signal having low-frequency characteristics, a cascade-array transceiver chip generating an output signal having high-frequency characteristics using the reference frequency signal through a signal generator provided therein, and an antenna transmitting the generated output signal to the outside in the form of an electromagnetic wave or receiving the electromagnetic wave from the outside.

IPC Classes  ?

• G01S 7/35 - Details of non-pulse systems
• G01S 13/40 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated with phase comparison between the received signal and the contemporaneously transmitted signal wherein the frequency of transmitted signal is adjusted to give a predetermined phase relationship

Abstract

Disclosed are a training data generation method and apparatus for an artificial intelligence visual analysis model. The training data generation method includes: (a) receiving a background image and object-related information; (b) generating a target object image that meets a condition based on the object-related information; (c) applying the background image to a depth estimation model to estimate depths of each pixel location and generate a depth map; (d) determining an insertion location and scale at which the target object image is inserted based on the depth map to generate a local object insertion image and a mask image, respectively; (e) simply synthesizing the local object insertion image and the background image and then generating a synthesis image reflecting a scale feature of the background image through a trained multi-scale visual analysis model; and (f) generating a final training image using the background image, the synthesis image, and the mask image.

IPC Classes  ?

• G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
• G06T 3/40 - Scaling of whole images or parts thereof, e.g. expanding or contracting
• G06T 7/50 - Depth or shape recovery
• G06V 10/762 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks
• G06V 10/771 - Feature selection, e.g. selecting representative features from a multi-dimensional feature space

Abstract

A cooling fluid circulation module includes: a first surface having a planar form and contacting a heating portion; a second surface opposite to the first surface and having a planar form, the second surface being spaced apart from the first surface; a first cooling channel extending between the first surface and the second surface in a first direction; a cooling fluid provided in the first cooling channel; and a plurality of first protrusions arranged along a plane on the second surface on which the first cooling channel extends, wherein each of the plurality of first protrusions may include a first surface inclined from the second surface by a first angle and a second surface inclined from the second surface by a second angle that is different than the first angle.

IPC Classes  ?

• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating
• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids

Abstract

Disclosed are a method and an apparatus for classifying patients with brain disorders based on EEG analysis. The method for classifying patients with brain disorders based on EEG analysis includes: (a) receiving an EEG data set with a clinical diagnosis label, wherein the EEG data set includes a plurality of EEG signals and age information; (b) augmenting the EEG data set through a deep learning-based screening model, and augmenting the EEG signals and the age information in different schemes; (c) training the deep learning-based screening model to classify EEG data of patients into a target clinical diagnosis label by using the augmented EEG signals and age information; and (d) predicting a brain diagnosis label of brain disorders by applying EEG data of patients to the trained deep learning-based screening model.

IPC Classes  ?

• A61B 5/372 - Analysis of electroencephalograms
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

The present invention relates to a self-assembled layer material for a solar cell, which is a compound with an asymmetric structure containing a halogen element, and a manufacturing method therefor, wherein the self-assembled layer material has a structure of chemical formula 1. The self-assembled layer material can be used for a hole transport layer in a perovskite solar cell to implement a high-efficiency next-generation perovskite solar cell.

IPC Classes  ?

• H10K 85/60 - Organic compounds having low molecular weight
• H10K 85/50 - Organic perovskitesHybrid organic-inorganic perovskites [HOIP], e.g. CH3NH3PbI3
• H10K 30/15 - Sensitised wide-bandgap semiconductor devices, e.g. dye-sensitised TiO2
• H10K 30/81 - Electrodes
• H10K 30/86 - Layers having high hole mobility, e.g. hole-transporting layers or electron-blocking layers
• H10K 30/85 - Layers having high electron mobility, e.g. electron-transporting layers or hole-blocking layers

Abstract

A nuclear fuel rod-cooling tube integrated assembly, according to the present invention, comprises: a nuclear fuel rod accommodating nuclear fuel; and a cooling tube having at least a portion formed to surround the circumference of the nuclear fuel rod, and the remaining portion extending to the other side connected to the outside of a reactor to transfer heat generated by nuclear fission inside the nuclear fuel rod to a heat exchanger installed outside the reactor.

IPC Classes  ?

• G21C 1/02 - Fast fission reactors, i.e. reactors not using a moderator
• G21C 15/257 - Promoting flow of the coolant using heat-pipes
• G21C 7/28 - Control of nuclear reaction by displacement of the reflector or parts thereof

Abstract

The present invention relates to an electrical stimulation device for promoting osteogenesis, which applies electrical stimulation to a bone defect part by using an induced current generated in vivo, and a method for promoting osteogenesis using same. The electrical stimulation device for promoting osteogenesis applies electrical stimulation to bone tissue, thereby helping the movement or proliferation of bone cells, promoting osteogenesis, and having high biocompatibility and safety by minimizing an invasive site in vivo. Furthermore, the electrical stimulation device for promoting osteogenesis can be implanted into a defect part of the gum bone, which is easily damaged by periodontal diseases, to reconstruct the bone, thereby effectively treating related diseases.

IPC Classes  ?

• A61N 1/40 - Applying electric fields by inductive or capacitive coupling
• A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
• A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
• A61C 8/02 - Means for transfixation of natural teeth
• A61F 2/28 - Bones

Abstract

The present invention relates to a pharmaceutical composition comprising a sclerostin inhibitor as an active ingredient for the prevention or treatment of diabetic eye disease, wherein the composition, by inhibiting sclerostin, not only reduces the expression levels of inflammatory cytokines significantly even under conditions of VEGF treatment and hyperglycemia, thereby exhibiting an excellent anti-inflammatory activity, but also is shown to have a significant angiogenic effect due to reduced expression of vascular adhesion markers and vascular endothelial growth factors, thereby inhibiting the principal characteristic of diabetic eye disease, the inflammatory response, and microvascular complications. In addition, the composition reduces oxidative stress caused by diabetes and does not induce cell death and thus can be useful as a preparation for the prevention or treatment of diabetic eye disease.

IPC Classes  ?

• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
• A61P 27/02 - Ophthalmic agents

Abstract

The present disclosure relates to a pulley-integrated cable actuator and an operation method thereof, more particularly to an actuator for operating cables. The pulley-integrated cable actuator includes: a base motor; a sun gear shaft of which the lower end portion is coupled to the center of the base motor, rotating by the motor rotation, and provided with a sun gear; a planet gear set consisting of multiple planet gears that mesh with the sun gear; and a ring gear-integrated pulley where a ring gear is formed on the inner side, meshing with the planet gear, and a pulley for winding a cable is formed on the outer side. The sun gear meshes with the inner space of the planet gear set. The ring gear is integrated with the pulley. The planet gear set is placed inside the pulley, minimizing the volume.

IPC Classes  ?

• B25J 9/10 - Programme-controlled manipulators characterised by positioning means for manipulator elements
• B25J 9/00 - Programme-controlled manipulators
• B25J 13/08 - Controls for manipulators by means of sensing devices, e.g. viewing or touching devices

Abstract

The present invention relates to a method for classifying fine dust exposure and predicting pregnancy-related complications caused by fine dust exposure. The method of the present invention is used for the classification of fine dust exposure and the prediction of pregnancy-related complications caused by fine dust exposure, which are based on biochemical markers, and thus is advantageous in that an appropriate prevention or intervention plan for chronic diseases and children's respiratory diseases caused by fine dust exposure can be constructed or, especially, pregnancy-related complications such as a low-birth-weight infant, premature birth and gestational diabetes, which are difficult to identify until birth or onset, can be quickly predicted with high accuracy.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The present invention relates to a composition for anti-inflammation and moisture enhancement of the skin, and, specifically, provides: a composition comprising an extract of Filipendula palmata (Pall.) Maxim. as an active ingredient so as to exhibit the effects of skin inflammation inhibition and moisture enhancement; and a pharmaceutical composition, a health functional food composition and a cosmetic composition, which comprise same.

IPC Classes  ?

• A61K 36/73 - Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A61P 17/00 - Drugs for dermatological disorders
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 8/9789 - Magnoliopsida [dicotyledons]
• A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
• A61K 8/60 - SugarsDerivatives thereof
• A61Q 19/00 - Preparations for care of the skin

Abstract

Disclosed are a high dynamic range imaging method and apparatus. The high dynamic range imaging method includes: (a) acquiring a first low dynamic range (LDR) image, a second LDR image, and a third LDR image having different exposure values; (b) applying the first, second, and third LDR images to a weight map estimation model to extract a weight map, and integrating the first, second, and third LDR images using the extracted weight map to generate an input feature map; and (c) applying the input feature map to a Swin-Fourier convolution network model to perform Fourier transform and convolution on the input feature map, and then connecting a reference feature map to generate a high dynamic range (HDR) image.

IPC Classes  ?

• G06T 5/90 - Dynamic range modification of images or parts thereof
• G06T 3/40 - Scaling of whole images or parts thereof, e.g. expanding or contracting
• G06N 3/0464 - Convolutional networks [CNN, ConvNet]

Abstract

The present invention pertains to a genome editing method based on a CRISPR/CAS9 system, and a use thereof. A CRISPR system using oligonucleotide-induced mutagenesis and mismatch guide RNA (sgRNA) according to the present invention achieves a significant genome editing effect on target DNA. Thus, it is expected that the CRISPR system of the present invention will be able to be used in a wide range of fields, such as compositions for gene editing using genetic scissors, genome level screening, therapeutic agents for treating various diseases including cancer, the development of compositions for disease diagnosis or imaging, and the development of transgenic plants and animals.

IPC Classes  ?

• C12N 15/90 - Stable introduction of foreign DNA into chromosome
• C12N 9/22 - Ribonucleases
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

Disclosed are a high dynamic range imaging method and apparatus. The high dynamic range imaging method includes: (a) acquiring a first low dynamic range (LDR) image, a second LDR image, and a third LDR image having different exposure values; (b) applying the first, second, and third LDR images to a weight map estimation model to extract a weight map, and integrating the first, second, and third LDR images using the extracted weight map to generate an input feature map; and (c) applying the input feature map to a Swin-Fourier convolution network model to perform Fourier transform and convolution on the input feature map, and then connecting a reference feature map to generate a high dynamic range (HDR) image.

IPC Classes  ?

• G06T 5/60 - Image enhancement or restoration using machine learning, e.g. neural networks
• G06T 5/10 - Image enhancement or restoration using non-spatial domain filtering
• G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
• H04N 23/80 - Camera processing pipelinesComponents thereof

Abstract

Disclosed are a method and apparatus for integrating image enhancement and training data generation using a generative recurrent neural network model. The method of integrating image enhancement and training data generation using a generative recurrent neural network model includes: (a) receiving a target image as input, and (b) applying the target image to a trained generative recurrent neural network model to selectively generate any one of a high-quality image with enhanced image quality and a low-quality image depending on a type of the target image.

IPC Classes  ?

• G06V 10/771 - Feature selection, e.g. selecting representative features from a multi-dimensional feature space
• G06T 7/00 - Image analysis

Abstract

Disclosed in the present invention are: a pharmaceutical composition for preventing or treating fibrotic diseases, comprising hyaluronan and proteoglycan link protein 1 (HAPLN1) or a gene encoding same as an active ingredient; and a method for preventing or treating fibrotic diseases using the composition. According to the present invention, fibrosis of cells or tissues is prevented and inhibited such that the occurrence or progression of various kinds of diseases caused by fibrosis is fundamentally suppressed, and thus the diseases can be prevented or treated.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 11/00 - Drugs for disorders of the respiratory system
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Abstract

The present inventors confirmed that when a brazzein expression recombinant vector for high expression of brazzein in Saccharomyces cerevisiae was prepared and a S. cerevisiae strain Y2805 was transformed with the recombinant vector, the expression level of brazzein was particularly high, thereby completing an optimal expression system for mass-producing brazzein. Further, when the brazzein expression system is cultured under the optimal culture conditions according to the present invention, the amount of brazzein produced is further increased, the purification process is simple, and costs are reduced. Therefore, it is expected that the brazzein expression system according to the present invention can be widely used for mass-producing and commercializing brazzein, which is a sweet protein.

IPC Classes  ?

• C07K 14/425 - Zeins
• C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Abstract

A semiconductor device thermal management module includes a thermal diffusion plate stacked on a semiconductor device for thermal diffusion of the semiconductor device and a heat spreader provided on the thermal diffusion plate, molded by a three-dimensional (3D) printing method, and having a channel through which a cooling fluid flows.

IPC Classes  ?

• H01L 23/367 - Cooling facilitated by shape of device
• H01L 21/48 - Manufacture or treatment of parts, e.g. containers, prior to assembly of the devices, using processes not provided for in a single one of the groups or

Abstract

The present invention relates to a method for manufacturing a micro 3D current collector by using a laser direct energy deposition process, and a method for manufacturing a 3D electrode for a supercapacitor and, more specifically, to a method for manufacturing a micro 3D current collector by using a laser direct energy deposition process, by which a micro metal structure can be directly printed on a substrate by using a laser-based direct energy deposition process and utilized as a current collector for a micro supercapacitor, and a current collector having micro metal wires printed thereon not only exhibits high electrical conductivity but also provides a larger area for depositing an energy storage active material due to the large surface area of the wires.

IPC Classes  ?

• B23K 26/342 - Build-up welding
• B23K 37/04 - Auxiliary devices or processes, not specially adapted for a procedure covered by only one of the other main groups of this subclass for holding or positioning work
• B23K 26/08 - Devices involving relative movement between laser beam and workpiece
• B23K 26/14 - Working by laser beam, e.g. welding, cutting or boring using a fluid stream, e.g. a jet of gas, in conjunction with the laser beamNozzles therefor
• H01G 11/22 - Electrodes
• H01G 11/58 - Liquid electrolytes

Abstract

A method for data clustering performed in a computing device including one or more processors and a memory that stores one or more programs executed by the one or more processors according to an embodiment includes receiving two or more multivariate discrete time series data as input and generating an embedding vector for each of the multivariate discrete time series data using a first artificial neural network, generating a similarity graph by performing a path-based connectivity test between embedding vectors for each of the two or more multivariate discrete time series data, predicting a label distribution for embedding vectors for each of the two or more multivariate discrete time series data using a second artificial neural network, and clustering the two or more multivariate discrete time series data based on the similarity graph and the label distribution.

IPC Classes  ?

• G06F 16/28 - Databases characterised by their database models, e.g. relational or object models
• G06F 16/22 - IndexingData structures thereforStorage structures
• G06F 16/2458 - Special types of queries, e.g. statistical queries, fuzzy queries or distributed queries

Abstract

The present disclosure relates to a manufacturing method of a micro 3D current collector using laser direct energy deposition and a manufacturing method of a 3D electrode for a supercapacitor, particularly to a manufacturing method of a micro 3D current collector using laser direct energy deposition where micro-metallic structures are directly printed onto a substrate using a laser-based direct energy deposition process, and then used as the current collectors of the micro-supercapacitors. The current collector with printed micro-metallic wires possesses high electric conductivity and a high aspect ratio as well as a larger surface area due to the extensive surface area of the wires, making it suitable for depositing energy storage active materials.

IPC Classes  ?

• B22F 10/28 - Powder bed fusion, e.g. selective laser melting [SLM] or electron beam melting [EBM]
• B22F 10/62 - Treatment of workpieces or articles after build-up by chemical means
• B33Y 10/00 - Processes of additive manufacturing
• B33Y 40/10 - Pre-treatment
• B33Y 40/20 - Post-treatment, e.g. curing, coating or polishing
• B33Y 80/00 - Products made by additive manufacturing
• C25D 9/02 - Electrolytic coating other than with metals with organic materials
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes

Abstract

The present invention relates to a composition for inducing stem cells to differentiate into astrocytes, containing CPI-455. By using the composition of the present invention, differentiation into astrocytes can be induced without using a conventional stem cell differentiation promoter, and it is also expected that the differentiated astrocytes can be used to effectively treat neurodegenerative diseases.

IPC Classes  ?

• C12N 5/079 - Neural cells
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

An element transfer device is provided. The element transfer device includes a cartridge including a plurality of element recesses each having a shape corresponding to a shape of a micro element, at least one wave energy generator configured to supply wave energy to the cartridge, a camera, and a processor. The processor is configured to primarily arrange a plurality of micro elements in the plurality of element recesses by supplying the wave energy to the cartridge accommodating the plurality of micro elements disposed in a fluid, obtain a first image by photographing the cartridge, and based on the first image, control a waveform and a frequency of the wave energy and control a secondary arrangement of disposing the micro elements in remaining element recesses in which the micro elements are not disposed.

IPC Classes  ?

• H01L 25/075 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group

Abstract

The present invention relates to, for oral delivery of biodrugs, a multi-arm polyethylene glycol-KLA peptide conjugate, a PEGylated distearoyl phosphatidylethanolamine-KLA peptide conjugate, a PAMAM dendrimer-KLAL peptide conjugate, and a composition for enhancing absorption, in the gastrointestinal tract, of a biodrug for oral administration containing same as oral absorption enhancers, the conjugates of the present invention reducing cytotoxicity due to the cell permeable properties of a KLA peptide, and maintaining a tight junction modulation function of KLA through effects such as increasing resistance to proteolytic enzymes in the gastrointestinal tract, so as to promote gastrointestinal absorption of biodrugs such as peptides, proteins, polysaccharides, and antibodies when orally administrated, and thus being able to be usefully employed in increasing the bioavailability of a drug.

IPC Classes  ?

• C08G 81/00 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
• C08G 65/48 - Polymers modified by chemical after-treatment
• C08G 69/10 - Alpha-amino-carboxylic acids
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

An apparatus for multi-label class classification based on a coarse-to-fine convolutional neural network includes: a processor; and a memory connected to the processor, in which the memory stores program instructions executed by the processor to generate a plurality of hierarchical structure based group labels for a plurality of classes to be classified by using a disjoint grouping method, predict classes which belong to the plurality of group labels, respectively among the plurality of classes by using a coarse-to-fine convolutional neural network including a main network and one or more subnetworks, complete learning of the coarse-to-fine convolutional network through the prediction, and classify one or more classes included in the image by receiving a feature map input from a last convolutional layer of the one or more subnetworks by the main network of the coarse-to-fine convolutional neural network of which learning is completed.

IPC Classes  ?

• G06N 3/08 - Learning methods

Abstract

The present disclosure relates to a biomimetic lightweight wearable suit and wearable suit design method, particularly to a biomimetic lightweight wearable suit that includes a suit portion that covers a body region from the knee to the sole of the foot; a force transmission pattern portion that surrounds around joints and muscles by mimicking a tendon to disperse a force of an actuator to a garment and a body; and an anchor point portion that is designed to surround a joint by mimicking a ligament.

IPC Classes  ?

• A61H 3/00 - Appliances for aiding patients or disabled persons to walk about
• A41D 17/00 - GaitersSpats
• A41H 3/00 - Patterns for cutting-outMethods of drafting or marking-out such patterns, e.g. on the cloth
• A61H 1/02 - Stretching or bending apparatus for exercising

Abstract

The present invention relates to a lightweight wearable suit based on biomimetics and a method for designing a wearable suit and, more specifically, to a lightweight wearable suit based on biomimetics, comprising: a suit unit that covers a body part from a knee to the sole of a foot; a force transmission pattern unit that surrounds joints and muscles to mimic tendons of a human body such that the force of an actuator is distributed to clothing and the body; and an anchor point unit designed to surround the joints by mimicking ligaments of the human body.

IPC Classes  ?

• B25J 9/00 - Programme-controlled manipulators
• A61H 1/02 - Stretching or bending apparatus for exercising

Abstract

The present invention relates to an oleaginous yeast Yarrowia lipolytica sur2 mutant strain and a method for producing and secreting, onto cell surfaces, sphingoid-based precursors, sphingosine and sphingolipids by using same. It has been identified that when a ceramidase gene is additionally introduced into a Ylsur2 deficient mutant strain, the secretion and production of dihydrosphingosine and sphingosine are increased and, further, it is has been identified that when a Ylsld1sur2 double mutant strain in which a SLD1 gene is additionally deficient in a Ylsur2 deficient mutant strain is prepared, growth recovery and sphingosine and human-type glucosylceramide secretion and production are increased.

IPC Classes  ?

• C12N 1/18 - Baker's yeastBrewer's yeast
• C12P 13/00 - Preparation of nitrogen-containing organic compounds
• C12P 17/06 - Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
• C12R 1/85 - Saccharomyces

Abstract

Provided is a direct cooling device for an integrated circuit configured to form a direct cooling portion with a flow channel through which cooling fluid may flow in a through via hole of a substrate constituting the integrated circuit, and to couple the substrate to a heat sink unit through a bonding portion formed integrally with the direct cooling portion, unlike the prior art in which only a ground circuit is possible through the through via hole, which derives the effect of increasing product reliability due to improved thermal management efficiency of the integrated circuit by directly cooling the semiconductor device as well as the ground circuit, and the effect of simplifying and miniaturizing the structure by implementing the cooling function using a circuit for grounding the semiconductor device even without forming an additional flow path structure for cooling the semiconductor device.

IPC Classes  ?

• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids
• H01L 23/498 - Leads on insulating substrates

Abstract

A direct cooling type semiconductor package unit includes a substrate made of a material capable of manufacturing a semiconductor device, and having a material layer for forming the semiconductor device stacked on one side of the substrate, and a flow channel through which a cooling fluid flows formed on the other side of the substrate to enable direct cooling of the semiconductor device using the cooling fluid; a packaging block disposed at a position spaced apart from the substrate for packaging the semiconductor device, and having an electrode electrically connected to the semiconductor device through wiring and placed thereon to be insulated; a heat sink unit disposed on a lower side of the packaging block and having a fluid movement region formed at a position corresponding to a flow channel of the substrate; and a thin film type structure disposed between the substrate and the heat sink unit for coupling between the substrate and the heat sink unit and being moldable to have pattern structures of various shapes through a dry film resist (DFR) lithography process.

IPC Classes  ?

• H01L 23/46 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids
• H01L 21/48 - Manufacture or treatment of parts, e.g. containers, prior to assembly of the devices, using processes not provided for in a single one of the groups or

Abstract

The present invention relates to a composition for repairing vascular degeneration and vascular injuries and preventing or treating vascular diseases, containing hyaluronan and proteoglycan link protein 1 (HAPLN1) as an active ingredient. More specifically, provided is a pharmaceutical composition and a health functional food composition for preventing or treating vascular diseases, containing HAPLN1 as an active ingredient. HAPLN1 inhibits and alleviates, in blood vessel walls, damage to the elastin fiber layer and loss of transgelin, and effectively inhibits the phosphorylation of NF-κB or focal adhesion kinase (FAK) in vascular smooth muscle cells (VSMCs), and thus can be used for preventing, alleviating or treating vascular injuries and various diseases caused by aging or a high-fat diet.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Disclosed are a deep learning model optimization method and apparatus for medical image segmentation. A deep learning model optimization method for medical image segmentation includes: (a) initializing a model parameter; (b) updating the model parameter by performing model-agnostic meta learning (MAML) on a model based on sample batch and applying a gradient descent algorithm to a loss function; (c) setting an optimizer parameter as the updated model parameter, performing one-shot meta-learning on the model, and then updating the optimizer parameter by applying the gradient descent algorithm to the loss function; and (d) updating the model parameter by reflecting the updated optimizer parameter.

IPC Classes  ?

• G06T 7/11 - Region-based segmentation

Abstract

Disclosed are a semi-distributed spectrum sensing method in cognitive IoT networks, and an apparatus thereof. The semi-distributed spectrum sensing method in cognitive IoT networks includes: (a) grouping, based on local information of pre-shared secondary terminals, each secondary terminal into each local cluster; (b) generating overlapping point information by calculating an overlapping range between directional antenna beams of the respective secondary terminals in the each local cluster, and determining a beam determination binary indicator of the each secondary terminal by using the overlapping point information; and (c) calculating and adjusting the overlapping range between the respective local clusters.

IPC Classes  ?

• H04W 16/14 - Spectrum sharing arrangements
• H04W 16/28 - Cell structures using beam steering
• H04W 84/18 - Self-organising networks, e.g. ad hoc networks or sensor networks

Abstract

The present invention relates to a method for producing a Korean fermented soybean lump and soybean paste having reduced aflatoxin and uniform quality using a seed fermented soybean lump. The concept and conditions of a seed fermented soybean lump and a method for producing a fermented soybean lump and soybean paste using same have been established, and a Korean fermented soybean lump and soybean paste not only having significantly reduced aflatoxin production but also having consistent quality and excellent flavor can be produced. Thus, the present invention can be helpfully used as a novel method for producing a Korean fermented soybean lump and soybean paste that addresses the issues of the existing method for producing a Korean fermented soybean lump and soybean paste, and as a fermented soybean lump and soybean paste produced by the method.

IPC Classes  ?

• A23L 11/70 - Germinated pulse products, e.g. from soy bean sprouts
• A23L 11/50 - Fermented pulses or legumesFermentation of pulses or legumes based on the addition of microorganisms
• A23P 20/17 - Apparatus or processes for coating with liquid or semi-liquid products by dipping in a bath
• A23P 10/00 - Shaping or working of foodstuffs characterised by the products
• C12N 1/14 - Fungi Culture media therefor
• C12R 1/66 - Aspergillus
• C12R 1/80 - Penicillium
• C12R 1/785 - Mucor

Abstract

The present invention relates to a method for manufacturing a biomaterial-based wearable sensor. The method for manufacturing a biomaterial-based wearable sensor according to the present invention is characterized by comprising: a) a first preparation step for preparing a base substrate in the form of a thin film; b) a second preparation step for placing an aqueous solution of graphene oxide and an aqueous silk fibroin solution in separate containers to prepare a material with which to coat the base substrate; c) a dip coating step for sequentially dip coating the base substrate with the graphene oxide aqueous solution and then the silk fibroin aqueous solution; and d) a drying step for drying the dip-coated base substrate by applying heat.

IPC Classes  ?

• A61B 5/087 - Measuring breath flow
• A61B 5/08 - Measuring devices for evaluating the respiratory organs
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

An apparatus for video representation learning according to an embodiment may extract video features from video data to generate a video embedding, extract image features from image data extracted from the video data to generate an image embedding, and extract audio features from audio data extracted from the video data to generate an audio embedding. Further, contrastive learning may be performed by generating a first compositional embedding based on the video embedding and the audio embedding, generating a second compositional embedding based on the video embedding and the audio embedding, generating a positive sample and a negative sample based on a correlation between the image embedding and the audio embedding, and then using the data.

IPC Classes  ?

• G06V 10/778 - Active pattern-learning, e.g. online learning of image or video features
• G06V 10/74 - Image or video pattern matchingProximity measures in feature spaces
• G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
• G06V 10/776 - ValidationPerformance evaluation
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
• G06V 20/40 - ScenesScene-specific elements in video content
• G10L 25/30 - Speech or voice analysis techniques not restricted to a single one of groups characterised by the analysis technique using neural networks

Abstract

The present invention relates to a flutter-based triboelectric nanogenerator and an operating method therefor. More specifically, the objective is to provide a charge-accumulating-flutter-based triboelectric nanogenerator (CAF-TENG) which has very high RMS current/average power density and portability, and which can provide a high-frequency output and excellent portability by using fluttering of a lightweight sheet and sheet flutter TENG.

IPC Classes  ?

• H02N 1/04 - Friction generators
• H10N 30/87 - Electrodes or interconnections, e.g. leads or terminals
• H10N 30/05 - Manufacture of multilayered piezoelectric or electrostrictive devices, or parts thereof, e.g. by stacking piezoelectric bodies and electrodes
• A62B 18/10 - Valves
• A62B 18/02 - Masks

Abstract

The present invention provides a method for non-destructively analyzing differentiation and maturity of a kidney organoid by using an electrochemical method. The method for analyzing differentiation and maturity of a kidney organoid, of the present invention, comprises the steps of: inoculating and culturing human-induced pluripotent stem cells on a conductive platform prepared according to the present invention; and differentiating the human-induced pluripotent stem cells into a kidney organoid, wherein, in the step of differentiating, a voltage is applied to the conductive platform so that a first electrochemical signal generated from specific cells of the kidney organoid and a second electrochemical signal generated from off-target cells are detected, and the differentiation and the maturity of the kidney organoid are analyzed according to the strength of the detected first and second electrochemical signals.

IPC Classes  ?

• G01N 27/48 - Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage
• G01N 33/483 - Physical analysis of biological material

Abstract

The present invention relates to a novel large-scale synthesis method for cynandione A, and has been completed by identifying that cynandione A can be synthesized on the gram-scale in merely two steps through continuous oxidation/regioselective arylation between 2,5-dihydroxyacetophenone and 2,4-dihydroxyacetophenone. That is, the synthesis method of the present invention comprises steps that are simpler and shorter than those of a conventional technique, and thus can be applied to mass synthesis of cynandione A through optimization. Particularly, it has been identified that the present invention can obtain high-purity cynandione A in a high yield even if column chromatography purification, which is difficult to be applied to mass synthesis, is performed only once. Therefore, the present invention enables large-scale synthesis of cynandione A, which is very efficient in terms of cost and time, and thus the present invention is expected to be effectively used as a synthesis method for preparing cynandione a, in various industries, medical and research fields and the like.

IPC Classes  ?

• C07C 45/62 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by reactions not involving the formation of C=O groups by hydrogenation of carbon-to-carbon double or triple bonds
• C07C 49/83 - Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
• C07C 49/825 - Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring

Abstract

Disclosed is a system for identifying a spatial resource for an IoT network, the system including a plurality of IoTDs (IoT devices) configured to identify an empty spatial resource using an identification parameter and provide spectrum identification information corresponding to a result thereof, and a radio resource harvesting edge (RRHE) configured to receive the spectrum identification information, optimize the identification parameter based on the received spectrum identification information, and provide the optimized identification parameter to the IoTDs.

IPC Classes  ?

• H04W 24/02 - Arrangements for optimising operational condition
• H04B 7/06 - Diversity systemsMulti-antenna systems, i.e. transmission or reception using multiple antennas using two or more spaced independent antennas at the transmitting station
• H04B 17/336 - Signal-to-interference ratio [SIR] or carrier-to-interference ratio [CIR]

Abstract

Disclosed is a method of manufacturing a transparent stretchable structure according to various embodiments of the present invention for achieving the above-described objects. The method includes providing a stretchable film and performing a rolling process on the stretchable film to form a transparent stretchable structure, wherein the stretchable film is provided through a thermoplastic elastomer based on physical crosslinking, and nanostructures in the transparent stretchable structure are oriented in one direction through the rolling process.

IPC Classes  ?

• C08J 5/18 - Manufacture of films or sheets
• C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules
• G09F 9/30 - Indicating arrangements for variable information in which the information is built-up on a support by selection or combination of individual elements in which the desired character or characters are formed by combining individual elements

Abstract

Disclosed are a method for preparing a highly stretchable CIP/PDMS composite, a highly stretchable CIP/PDMS composite prepared thereby, and a highly stretchable electromagnetic (EM) noise suppressor including the same. The method for preparing the highly stretchable CIP/PDMS composite includes a first step of adding and mixing CIPs (Carbonyl Iron Powders) to and with a PDMS (Polydimethylsiloxane) solution to produce a first mixed solution; a second step of adding and mixing a curing agent to and with the first mixed solution to produce a second mixed solution; and a third step of transferring the second mixed solution into a mold and then curing the second mixed solution in the mold.

IPC Classes  ?

• C08K 3/18 - Oxygen-containing compounds, e.g. metal carbonyls

Abstract

A hydrogen liquefaction apparatus is disclosed. The disclosed hydrogen liquefaction apparatus comprises: a pre-cooling unit configured to cool externally introduced gaseous hydrogen with a hydrogen refrigerant, a nitrogen refrigerant, and a carbon dioxide refrigerant to generate pre-cooled hydrogen; a cryogenic cooling unit configured to additionally cool the pre-cooled hydrogen generated in the pre-cooling unit with a hydrogen refrigerant to generate cryogenic hydrogen; an expansion valve configured to expand the cryogenic hydrogen generated in the cryogenic cooling unit to generate liquid hydrogen; and a hydrogen refrigerant expander configured to expand the hydrogen refrigerant discharged from the cryogenic cooling unit to additionally cool.

IPC Classes  ?

• F25J 1/00 - Processes or apparatus for liquefying or solidifying gases or gaseous mixtures
• C01B 3/00 - HydrogenGaseous mixtures containing hydrogenSeparation of hydrogen from mixtures containing itPurification of hydrogen

Abstract

A hydrogen liquefaction device is disclosed. The disclosed hydrogen liquefaction device comprises: a pre-cooling unit configured to cool externally introduced gaseous hydrogen with nitrogen refrigerant and carbon dioxide refrigerant to generate pre-cooled hydrogen; a cryogenic cooling unit configured to further cool the pre-cooled hydrogen, generated by the pre-cooling unit, with nitrogen refrigerant to generate cryogenic hydrogen; a hydrogen expander configured to expand the cryogenic hydrogen generated by the cryogenic cooling unit to generate liquid hydrogen; and a liquid hydrogen storage tank configured to store the liquid hydrogen discharged from the hydrogen expander, wherein the device is configured to recirculate evaporated hydrogen gas generated in the liquid hydrogen storage tank back to the pre-cooling unit.

IPC Classes  ?

• F25J 1/00 - Processes or apparatus for liquefying or solidifying gases or gaseous mixtures
• C01B 3/00 - HydrogenGaseous mixtures containing hydrogenSeparation of hydrogen from mixtures containing itPurification of hydrogen

Abstract

Disclosed are a lead-free photodetector and a method for manufacturing the same. The lead-free photodetector includes a light-side electrode, a light-side conductive layer formed on the light-side electrode, a perovskite layer formed on the light-side conductive layer, a rear-side conductive layer formed on the perovskite layer, and a rear-side electrode formed on the rear-side conductive layer.

IPC Classes  ?

• H10K 85/50 - Organic perovskitesHybrid organic-inorganic perovskites [HOIP], e.g. CH3NH3PbI3
• H01G 9/00 - Electrolytic capacitors, rectifiers, detectors, switching devices, light-sensitive or temperature-sensitive devicesProcesses of their manufacture
• H01G 9/20 - Light-sensitive devices
• H10K 85/10 - Organic polymers or oligomers
• H10K 85/20 - Carbon compounds, e.g. carbon nanotubes or fullerenes
• H10K 85/60 - Organic compounds having low molecular weight

Abstract

The present invention relates to a manufacturing method and a manufacturing apparatus for calcium formate and, more particularly, to a manufacturing method and a manufacturing apparatus for calcium formate, wherein the formic acid-amine adduct prepared in a process using hydrogenation of carbon dioxide is reacted with a calcium compound, whereby calcium formate can be manufactured and separated in a simple process while excluding complicated separation processes and co-bases required by conventional formic acid manufacturing processes, with the resultant improvement of economical benefit and efficacy in the process.

IPC Classes  ?

• C01F 11/46 - Sulfates
• B01J 23/46 - Ruthenium, rhodium, osmium or iridium

Abstract

2 layers and has different thickness and number of growth layers from the lower high resistance layer. And the lower high resistance layer and the upper low resistance layer may form a homojunction. The heat transfer characteristic of the lower high resistance layer may increase by the interface induced Seebeck effect with the upper low resistance layer. The transition dichalcogenide homojunction structure may generate the interface induced Seebeck effect at the interface of the homojunction to generate a thermal voltage. Further, the transition metal dichalcogenide homojunction structure may measure the Seebeck effect of the lower high resistance layer using the upper low resistance layer without separate measurement equipment.

IPC Classes  ?

• H10N 10/852 - Thermoelectric active materials comprising inorganic compositions comprising tellurium, selenium or sulfur
• H10N 10/01 - Manufacture or treatment

Abstract

Provided in one embodiment of the present invention is a method for generating an artificial intelligence model by which a breath sound classification model generation device provides breath sound classification information to a user. The method comprises the steps of: generating training data including breath sound data and labeling data in which the corresponding breath sound data is labeled as normal breathing or abnormal breathing; converting the breath sound data into a mel-spectrogram; and generating a breath sound classification model trained to infer whether the specific breath sound data is normal breathing or abnormal breathing on the basis of the labeling data and the training data including the mel-spectrogram.

IPC Classes  ?

• A61B 5/08 - Measuring devices for evaluating the respiratory organs
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 7/00 - Instruments for auscultation
• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Disclosed is a LED device in which a plane of a substrate is patterned in a C2 symmetrical manner such that upper, lower, left, and right areas thereof are distinguished from each other. Further, in positioning the electrodes, one conductivity-type electrode is positioned on a center of the substrate, and electrodes of a conductivity-type different from that of the center electrode are positioned in an opposite manner to each other around the center electrode and are spaced from the center electrode by the same distance. Thus, even when the LED device is rotated by 180 degrees, the electrodes may match with each other. Further, disclosed are a method arranging C2 symmetrical LED devices using wave energy, and a method for fabricating a display module using the arranged C2 symmetrical LED devices. The C2 symmetrical LED device has the 180 degrees rotation symmetry. Thus, upper, lower, left, and right areas thereof are distinguished from each other, and thus, the devices may be oriented very accurately.

IPC Classes  ?

• H01L 33/12 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a stress relaxation structure, e.g. buffer layer
• H01L 25/075 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
• H01L 33/24 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a particular shape, e.g. curved or truncated substrate of the light emitting region, e.g. non-planar junction
• H01L 33/38 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the electrodes with a particular shape

Abstract

An operating method of a calibration system for a display device obtains image information about an image displayed on display device and wavelength information about pixels of the image information using a hyperspectral camera included in an electronic device, transmits the obtained image information and wavelength information to a first application in the electronic device, generates calibration data about the obtained image information and wavelength information through the first application and transmits the calibration data to a second application in the display device, and performs color calibration of the display device based on the calibration data transmitted to the second application to display a color calibrated image.

IPC Classes  ?

• G09G 3/20 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix
• G06T 7/90 - Determination of colour characteristics

Abstract

Disclosed are a thin-film transistor and a method for manufacturing the same. The thin-film transistor includes: a substrate serving as a gate electrode; a gate insulating film formed on the substrate; a metal layer formed on the gate insulating film; a metal oxide layer formed on the metal layer and covering an entirety of a surface of the metal layer; a metal oxide semiconductor layer formed so as to cover an entirety of a surface of the metal oxide layer; and a source/drain electrode formed on the metal oxide semiconductor layer, wherein the thin-film transistor further comprises an oxygen depletion layer disposed in an area of the metal oxide semiconductor layer adjacent to the metal oxide layer, wherein the metal oxide semiconductor layer is obtained by crystallizing an amorphous metal oxide semiconductor layer under heat-treatment.

IPC Classes  ?

• H01L 29/786 - Thin-film transistors
• H01L 29/66 - Types of semiconductor device
• H01L 29/417 - Electrodes characterised by their shape, relative sizes or dispositions carrying the current to be rectified, amplified or switched

Abstract

Disclosed are a method for manufacturing a thermochromic film, a thermochromic film manufactured using the same, and a smart window including the thermochromic film. The method for manufacturing the thermochromic film includes a first step of forming a metal thin-film on a substrate; and a second step including: heating a first solution containing a vanadium dioxide precursor to perform hydrothermal synthesis of vanadium dioxide; dispersing the synthesized vanadium dioxide in a solvent to prepare ink; and applying the ink onto a surface of the metal thin-film formed on the substrate to coat vanadium dioxide on the metal thin-film.

IPC Classes  ?

• B05D 5/06 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain multicolour or other optical effects
• G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour

Abstract

According to the present disclosure, a circuit for cancelling an off-set voltage included in an output voltage of an electronic component includes: a first resistor having one end connected to a bias voltage terminal; a second resistor connected to the first resistor, and having one end connected to the bias voltage terminal; a third resistor having one end connected to the first resistor and the other end connected to a ground terminal; and a transistor having one end connected to the second resistor and the other end connected to the ground terminal, and applied with an output voltage including an off-set voltage from a sensor.

IPC Classes  ?

• H03F 3/45 - Differential amplifiers
• H03F 1/30 - Modifications of amplifiers to reduce influence of variations of temperature or supply voltage

Abstract

Provided is a method for prevention and treatment of age-related macular degeneration through the suppression of cathepsin S expression, and retinal pigment epithelial cells in which cathepsin S is knocked down can be usefully used as a target for preventing or treating dry and wet age-related macular degenerations, in that the expression level of inflammatory cytokines and complement activity are reduced even under oxidative stress conditions, and the retinal pigment epithelial cells are not only more effective in suppressing complement activity than NF-κB inhibitors, but also suppress intracellular neovascularization and tube formation.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

A microfluidic bladder cancer mimic and the use thereof is provided. The bladder cancer mimic is produced through 3D printing, which may more accurately reflect in vivo environments than conventional two-dimensional cell models and may be more simply produced than animal models. A method of screening bladder cancer treatment substances using a lab-on-a-chip including the bladder cancer mimic that may be used for the development of anticancer therapeutic agents and may also be used to develop patient-specific therapeutic agents by using patient-derived bladder cancer cells.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

Bifidobacterium breveBifidobacterium breveBifidobacterium breve JKL2022 strain of the present invention, and the conjugated linoleic acid (CLA) produced thereby can be widely used in probiotic compositions, pharmaceutical compositions, health functional food compositions, feed additive compositions, and food additive compositions.

IPC Classes  ?

• C12N 1/20 - BacteriaCulture media therefor
• C12P 7/6431 - Linoleic acids [18:2[n-6]]
• A61K 35/745 - Bifidobacteria
• A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
• A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
• C12R 1/01 - Bacteria or actinomycetales

Abstract

Provided is a composition for preventing, alleviating or treating neurodegenerative disorders, comprising, as an active ingredient, a Davallia mariesii extract or a fraction thereof, or a compound isolated therefrom.

IPC Classes  ?

• A61K 36/11 - Pteridophyta or Filicophyta (ferns)
• A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
• A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
• A23K 20/163 - SugarsPolysaccharides

Abstract

The present invention relates to a method for diagnosing degenerative brain disease by detecting intron retention using transcriptome analysis, and more specifically, to a method for diagnosing degenerative brain disease by detecting intron retention in transcripts in any one or more biological samples selected from the group consisting of blood, blood plasma, blood cells, and serum provided from a subject.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• C12Q 1/6869 - Methods for sequencing

Abstract

The present invention relates to a pulley-integrated cable actuator and an operation method thereof and, more specifically, to a pulley-integrated cable actuator for actuating cables, comprising: a base motor; a sun gear shaft of which the lower end portion is coupled to the center of the motor and which is axially rotated by the rotation of the motor and is provided with a sun gear; a planet gear set comprising a plurality of planet gears, each meshing with the sun gear; and a ring-gear-integrated pulley having formed on the inner surface a ring gear to mesh with the planet gears and having provided on the outer surface a pulley around which a cable is wound, wherein the sun gear is meshed with the inner space of the planet gear set, the ring gear is integrated with the pulley, and the planet gear set is arranged inside the pulley, thereby minimizing the volume.

IPC Classes  ?

• B25J 9/10 - Programme-controlled manipulators characterised by positioning means for manipulator elements
• B25J 9/00 - Programme-controlled manipulators

Abstract

A device and a method for predicting a disease of interest on the basis of a deep neural network, and a computer-readable program therefor are disclosed. The device for predicting a disease of interest on the basis of a deep neural network, according to the present invention, comprises: a data collection unit for collecting patient-specific medical diagnosis data; an input data generation unit, which embeds, as binary vectors, medical diagnosis data on each patient so as to generate input data; a disease-of-interest prediction model generation unit, which learns the input data as learning data so as to generate a disease-of-interest prediction model based on a deep neural network, the disease-of-interest prediction model generation unit generating compression data with a reduced dimension of the input data and learning so that answer data corresponding to the compression data is output when the compression data is input, thereby generating the disease-of-interest prediction model; and a disease-of-interest prediction unit, which inputs the input data into the disease-of-interest prediction model so as to predict, according to medical diagnosis data on a corresponding patient, whether a disease of interest occurs. Therefore, according to the present invention, a disease of interest can be effectively predicted using only existing diagnostic history of a patient. Thus, patients are provided with the opportunity to self-diagnose, and doctors can efficiently perform predictive diagnosis for a disease of interest.

IPC Classes  ?

• G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
• G06N 3/04 - Architecture, e.g. interconnection topology
• G06N 3/08 - Learning methods

Abstract

A method and apparatus for training a fake image discriminative model according to an embodiment of the present disclosure includes generating one or more fake images for a real image by selecting one or more encoding layers and one or more decoding layers from a generator network of an autoencoder structure, generating a training image set based on the one or more fake images, and training a classifier for discriminating a fake image by using the training image set.

IPC Classes  ?

• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
• G06V 10/778 - Active pattern-learning, e.g. online learning of image or video features
• G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects

Abstract

The present invention relates to a method for screening a target gene using a clustered regularly interspaced short palindromic repeats interference (CRISPRi) system and uses thereof. According to the present disclosure, it is expected that the method may be used in wide fields as a tool for genome-scale gene function profiling and studying organisms poorly developed in genetic technology, including pathogens or industrially useful strains or cell lines, and as a platform for electronic regulatory network engineering of genes.

IPC Classes  ?

• C12P 17/10 - Nitrogen as only ring hetero atom
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli

Abstract

The present invention relates to a composition for preventing or treating fibrotic diseases, the composition comprising a dimethylchalcone derivative as an active ingredient, and more specifically, to a composition for alleviating, preventing, or treating fibrotic diseases, the composition comprising a derivative of 2',4'-dihydroxy-6'-methoxy-3'5'-dimethylchalcone as an active ingredient. The DMC derivatives according to the present invention exhibit the effect of inhibiting the expression of PAI-1 and α-SMA by TGFβ1. Thus, the DMC derivatives can effectively prevent or treat various fibrotic diseases including renal fibrosis.

IPC Classes  ?

• A61K 31/12 - Ketones
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives

Abstract

The present invention relates to novel compounds based on the meta-substitution of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone (DMC). According to the present invention, novel DMC derivatives that are meta-substituted using cheap phloroglucinol or the like as a starting material can be simply and efficiently synthesized. Specifically, DMC derivatives according to the present invention were confirmed to have a good fatty acid oxidation effect compared to existing DMC derivatives, and thus are expected to be used as a therapeutic material for metabolic diseases.

IPC Classes  ?

• C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
• C07C 43/225 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen

Abstract

A phototransistor element and a method for manufacturing same are disclosed. The present invention comprises a quantum dot layer including a first quantum dot, a second quantum dot, and a third quantum dot having different sizes to be able to absorb and detect red light (R), green light (G), and blue light (B) having different wavelengths, respectively, wherein when electrons and holes are generated by light through a heterojunction structure of the quantum dot layer and a semiconductor channel layer of a phototransistor element, the electrons move to the semiconductor channel layer and the holes are trapped in the quantum dot layer to cause a photogating effect and thus generate a current, thereby exhibiting a synaptic memory effect.

IPC Classes  ?

• H01L 31/0352 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their shape or by the shapes, relative sizes or disposition of the semiconductor regions
• H01L 31/112 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by field-effect operation, e.g. junction field-effect photo- transistor
• H01L 31/18 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof

Abstract

The present invention relates to a novel compound having inhibitory activity against epidermal growth factor receptor tyrosine kinase and to uses thereof, and provided in the present invention are a compound represented by chemical formula I, a solvate, a stereoisomer or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same.

IPC Classes  ?

• C07D 498/10 - Spiro-condensed systems
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 35/00 - Antineoplastic agents
• C07D 498/08 - Bridged systems

Abstract

A power transaction mediation method and an apparatus thereof are disclosed. The power transaction mediation method comprises the steps of: deriving a power sales price on the basis of a power sales benefit for a prosumer's surplus power sales, wherein the power sales price is derived by reflecting a transaction ratio index to the power sales price by considering a period of recovering an installation cost of renewable energy production facilities of the prosumer; deriving a power purchase price on the basis of a consumer's power purchase benefit for surplus power purchase; deriving a power transaction price to satisfy a power transaction price range using the power sales price and the power purchase price; and mediating the transaction of the surplus power at the derived power transaction price.

IPC Classes  ?

• G06Q 50/06 - Energy or water supply
• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
• G06Q 30/08 - Auctions

Abstract

Smart energy trading system and method are disclosed. The smart energy trading system comprises: at least one prosumer; at least one consumer; and a virtual power bank which forms a virtual grid, which is a virtual connection chain for energy trades between the prosumer and consumer, and temporarily stores surplus power of the prosumer via the virtual grid and brokers the sale of the surplus power to a consumer satisfying energy trade constraints, wherein the virtual grid comprises a virtual connection chain connected to an electric power company and is established by using an energy grid previously established by the electric power company.

IPC Classes  ?

• G06Q 50/06 - Energy or water supply
• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
• G06Q 30/08 - Auctions

Abstract

Provided is a composition comprising a dimethylchalcone derivative for prevention or treatment of metabolic diseases and, more specifically, to a compositioncomprising a derivative of 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone as an active ingredient for the alleviation, prevention, or treatment of various metabolic diseases.

IPC Classes  ?

• A61K 31/12 - Ketones
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

The present disclosure relates to a composition for preventing or treating lung cancer, including ortho topolin riboside (oTR) as an active ingredient, wherein oTR showed the highest cytotoxicity among all tested compounds against NSCLC cells, oTR reduced synthesis of amino acid and pyrimidine as well as glycolytic function in NSCLC cells and xenograft tumors.

IPC Classes  ?

• A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
• A61P 35/00 - Antineoplastic agents
• A61P 11/00 - Drugs for disorders of the respiratory system

Abstract

Disclosed herein are a method of manufacturing dry binders for electrodes usable in a dry electrode method by using a mixture of polymer powder containing a hydroxyl group (—OH) and polytetrafluoroethylene, and a method of manufacturing dry electrodes including dry binders.

IPC Classes  ?

• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/04 - Processes of manufacture in general
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• H01M 4/66 - Selection of materials
• C08L 27/18 - Homopolymers or copolymers of tetrafluoroethene
• C08L 71/02 - Polyalkylene oxides
• C08J 3/00 - Processes of treating or compounding macromolecular substances
• C08J 3/20 - Compounding polymers with additives, e.g. colouring
• C08K 3/04 - Carbon

Abstract

The present disclosure provides nanoparticles including laminarin and a near-infrared responsive photosensitizer covalently bonded thereto, and a composition for preventing, diagnosing, or treating arteriosclerosis comprising the same as an active ingredient. According to the present disclosure, not only the atherosclerotic plaque targeting and plaque-penetrating properties can be enhanced as compared to conventional photodynamic therapy, thus capable of being usefully used for in vivo imaging of atherosclerotic plaques, but also the size of atherosclerotic plaques is reduced by inducing apoptosis of macrophages in atherosclerotic plaques, thus capable of stabilizing atherosclerotic plaques. Therefore, the composition comprising the nanoparticles of the present disclosure as an active ingredient is expected to be usefully used for the prevention, diagnosis and/or treatment of arteriosclerosis, in that photodynamic therapy and image diagnostic of arteriosclerosis can be performed simultaneously or sequentially.

IPC Classes  ?

• A61K 31/716 - Glucans
• A61K 49/00 - Preparations for testing in vivo
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

The present invention relates to an artificial bladder system having a double space divided by a partition wall and a wireless, non-powered urine fullness sensor using an RFID technology, which provides an artificial bladder system comprising: an outer wall that forms the outer shape of the artificial bladder, is inserted into the body, and has an inner space; a partition wall, wherein both ends are fixed to the inside of the outer wall, the inner space of the outer wall is divided into a double space of a urine reservoir and a working fluid space, and it is deformable according to amounts of the urine and the working fluid; and a urine fullness sensor installed in the working fluid space and sensing a urine fullness degree based on the deformation of the partition wall.

IPC Classes  ?

• A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
• G01L 9/00 - Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by electric or magnetic pressure-sensitive elementsTransmitting or indicating the displacement of mechanical pressure-sensitive elements, used to measure the steady or quasi-steady pressure of a fluid or fluent solid material, by electric or magnetic means

Abstract

A cooling apparatus for a power module including a plurality of cooling modules provided to be in contact with each of both surfaces of the power module, in which the cooling module includes a manifold cover provided with a plurality of guide walls extending in a first direction in a state of being spaced apart from each other and a pin plate having one surface being in contact with the power module and having a plurality of pins extending in a second direction crossing the first direction formed on the other surface thereof.

IPC Classes  ?

• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

Abstract

The present invention relates to a method for producing cultured meat by utilizing a fetal bovine serum (FBS) substitute derived from butchery by-products and, more specifically, to: a method for preparing a medium additive (an FBS substitute) for culturing cultured meat from butchery by-products; a medium additive for culturing cultured meat prepared by the method; a medium composition for culturing cultured meat comprising the additive; and a method for preparing cultured meat by using same. By using the medium additive (the FBS substitute) for culturing cultured meat prepared by the unique method of the present invention, the traditional fetal bovine serum (FBS), which has a high unit cost and the ethical issue of having to be collected from live calves, is completely substituted or jointly used, and thus the amount of fetal bovine serum (FBS) use can be reduced and the product efficiency of the cultured meat can be enhanced. Further, by increasing the utilization of butchery by-products which are inevitably generated during butchering of livestock for producing meat, the present invention provides the advantages of increasing the value of the butchery by-products and increasing economic advantages such as reduced disposal costs and increased incomes.

IPC Classes  ?

• C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells

Abstract

The present invention relates to a composition comprising LGK974 for preventing or treating inflammatory renal disease, and a treatment method. LGK974 reduces, in the kidney, inflammatory cytokines or chemokines such as TNF-α, IFN-γ, IL-1α, IL-1β, IL-6, IL-12, CCL-2, CCL-3, CCL-4 and CCL-5, reduces kidney damage biomarkers selected from serum creatinine, serum cystatin C, or serum blood urea nitrogen (BUN), and inhibits inflammation amplification caused by the interaction between p-IκB (an NF-κB pathway protein) and β-TrCP (a Wnt pathway protein), and thus exhibits the exceptionally excellent effect of preventing or treating inflammatory renal disease. In addition, LGK974 is currently undergoing clinical trials in patients with pancreatic cancer, colon cancer, melanoma, breast cancer, head and neck cancer, cervical cancer, esophageal cancer and lung cancer, and thus can be used in the rapid development, through drug repositioning, of pharmaceuticals for preventing or treating inflammatory kidney disease, with few side effects and ensured safety.

IPC Classes  ?

• A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives

Abstract

The present invention relates to a wearable sensor. The wearable sensor according to the present invention comprises: a deformation layer which is coupled to an object with deformation behavior, such as a wearable device or a user's body part, to be deformed according to the behavior of the object and is formed of a deformable and shape-recoverable material so as to be recoverable to the original shape after being deformed; and a sensing layer which is laminated on the deformation layer and comprises an eco-friendly material made of a biodegradable material harmless to the human body, and a conductive material causing a change in the resistance according to deformation.

IPC Classes  ?

• A61B 5/024 - Measuring pulse rate or heart rate
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb

Abstract

The present invention relates to a coarse-to-fine convolutional neural network-based multilabel class classification apparatus that generates a hierarchical structure-based plurality of group labels for a plurality of classes to be classified, by using a disjoint grouping method, predicts a class belonging to each of the plurality of group labels from among the plurality of classes by using a coarse-to-fine convolutional neural network including a main network and one or more sub-networks, completes training the coarse-to-fine convolutional neural network through prediction, and when an image including an object corresponding to a class is input, classifies the class included in the image as the main network of the coarse-to-fine convolutional neural network that has been trained receives an input of a feature map input from a last convolutional layer of the one or more sub-networks.

IPC Classes  ?

• G06K 9/62 - Methods or arrangements for recognition using electronic means
• G06N 3/08 - Learning methods

Abstract

The present invention relates to a pseudo foamy virus prepared using a 2-plasmid system. The 2-plasmid system according to the present invention has the advantage of being economical for system production due to using a significantly smaller number of auxiliary plasmids than conventional plasmid systems using three or more auxiliary plasmids. In addition, it was confirmed that the pseudo foamy virus prepared through the 2-plasmid system infects the target cell once, and viruses produced thereafter in the target cell are not infectious. In addition, it was confirmed that the exogenous gene introduced by the pseudo foamy virus is stably and permanently expressed. Therefore, the 2-plasmid system and the pseudo foamy virus produced thereby according to the present invention can be variously utilized in the fields of exogenous protein expression, genetic disease treatment, and vaccines.

IPC Classes  ?

• C12N 15/86 - Viral vectors

Abstract

The present invention relates to a composition comprising a peony extract for preventing, alleviating, or treating muscular dystrophy. The composition comprising a peony extract can be used to reduce muscle damage and HMGB1 levels, inhibit the HMGB1-TLR4-NFkB signaling, or lower cytokine and chemokine levels, thereby effectively preventing, alleviating, or treating muscular dystrophy.

IPC Classes  ?

• A61K 36/65 - Paeoniaceae (Peony family), e.g. Chinese peony
• A61P 21/04 - Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives

Abstract

Disclosed are a behavior recognition method using deep learning, and a device thereof. The behavior recognition method using deep learning may comprise the steps of: sampling a video and generating a video clip composed of the sampled frames; generating a differential image set between the sampled frames; generating a spatiotemporal combined feature map having temporal features and spatial features by applying the sampled frames and the differential image set to a deep learning-based behavior recognition model; and then calculating a bidirectional exponential moving average to adjust weights of the spatiotemporal combined feature map and thereby classify behaviors via late fusion with a temporal saliency map having three-dimensional features of the sampled frames.

IPC Classes  ?

• G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
• G06V 10/40 - Extraction of image or video features
• G06N 3/08 - Learning methods

Abstract

A method for generating artificial neural network architecture includes selecting any one of a plurality of artificial neural network architectures as a backbone architecture, calculating weights of a plurality of candidate operation blocks applicable to each stage for each of one or more stages constituting the backbone architecture, replacing or removing at least one of the plurality of candidate operation blocks based on the calculated weight, and repeatedly performing the calculating of the weight and the replacing or removing the at least one candidate operation block by a preset number of times to configure a final candidate operation block set for each stage and select any one of the final candidate operation block as an operation block of a corresponding stage.

IPC Classes  ?

• G06N 3/04 - Architecture, e.g. interconnection topology
• G06N 3/08 - Learning methods

Abstract

A hyperspectral image sensor includes an optical irradiator configured to irradiate light to a partial region of an object, an optical detector configured to receive detection light generated in the partial region in response to the irradiated light and generate spectrum signals, each of the spectrum signals corresponding to a respective sub-region of a plurality of sub-regions included in the partial region, and a processor configured to generate a hyperspectral image of the partial region based on the spectrum signals.

IPC Classes  ?

• G01J 3/28 - Investigating the spectrum
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details

Abstract

The present invention relates to: a nanoplatform with which the differentiation of stem cells is possible without the addition of exogenous differentiation factors; and a method for manufacturing same. The nanoplatform comprises: a nanopit array in which a plurality of holes are formed; single metal-organic framework (MOF) nanoparticles embedded in each of the plurality of holes; and stem cell differentiation factors loaded in the MOF nanoparticles.

IPC Classes  ?

• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12N 5/0793 - Neurons

Abstract

A sensing portion of the tension type smart shoe unit is arranged to extend across the width of thea sole of a wearer so that foot pressure applied through the sole is exerted thereon, and a connection portion of the tension type smart shoe unit is fixed by connection to a connecting portion of a circuit block. Thus, even when the foot pressure exerted is biased to the left or right while the wearer is walking, only a portion where the pressure is biased is not sensed in contrast with a conventional case in which piezoelectric sensors are mounted, but the sensing portion is deformed, and the magnitude of an electrical output signal corresponding to the deformation is calculated using an equation of a relationship with a load. Consequently, the amount of foot pressure may be precisely measured even with a simple configuration.

IPC Classes  ?

• A61B 5/103 - Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
• C01B 32/168 - After-treatment
• C09D 183/04 - Polysiloxanes
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

Agrimonia pilosaGalla rhoisGalla rhois extract as an active ingredient, and does not cause side effects to a human body and thus exhibits excellent safety, and also has excellent antiviral activity due to a cell lesion effect through a virus-dependent pathway, an influenza virus-related gene reducing effect, and the like. Further, the present invention not only is confirmed with an in vivo antiviral effect but also has notably excellent antiviral activity in the active ingredient of the mixed extracts, and thus may be utilized for a composition for preventing, treating or relieving influenza virus infection.

IPC Classes  ?

• A61K 36/73 - Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
• A61K 36/22 - Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
• A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives

Abstract

An auxiliary circuit for reducing an output voltage ripple of a DC-DC converter includes: a capacitor configured to perform charging and discharging, a main buck converter including a first switch and a second switch connected to a voltage source, and a first inductor connected between the capacitor and a contact point of the first switch and the second switch, the first inductor having a first inductor current that flows therethrough, and an auxiliary buck converter including a third switch and a fourth switch respectively connected to the first switch and the second switch in parallel, and a second inductor connected between the capacitor and a contact point of the third switch and the fourth switch, the second inductor having a second inductor current that flows therethrough, and the auxiliary buck converter configured to control the second inductor current by generating two envelopes with different heights to compensate for a difference between the first inductor current and an output current.

IPC Classes  ?

• H02M 1/15 - Arrangements for reducing ripples from DC input or output using active elements
• H02M 1/00 - Details of apparatus for conversion
• H02M 1/08 - Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters
• H02M 1/14 - Arrangements for reducing ripples from DC input or output
• H02M 3/156 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators
• H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load

Abstract

The present disclosure relates to an elastic unit with adjustable elasticity and elastic modulus and to an operation method thereof. In particular, the present disclosure relates to an elastic unit with adjustable elasticity and elastic modulus, which comprises: an elastic element having a plurality of division areas longitudinally; and elasticity adjustment modules that are laid out in each of the division areas of the elastic element and activate or inactivate the elastic element partially depending on the division areas to adjust an elasticity and an elastic modulus of the elastic element.

IPC Classes  ?

• A41D 13/05 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
• A63B 21/055 - Exercising apparatus for developing or strengthening the muscles or joints of the body by working against a counterforce, with or without measuring devices using resilient force-resisters extension element type

Abstract

The present disclosure relates to a method and an apparatus for measuring motility of ciliated cells in a respiratory tract. The method includes the operations of: acquiring image data including a plurality of frames of respiratory tract organoids; identifying positions of ciliated cells by performing motion-contrast imaging on the image data; when a region of interest (ROI) related to the position of the ciliated cells is selected, measuring a ciliary beat frequency (CBF) related to motility of cilia included in the selected region of interest using cross-correlation between the plurality of frames; and expressing the cilia included in the region of interest in a preset display method on the basis of the range of the measured ciliary beat frequency.

IPC Classes  ?

• G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]
• G06V 10/74 - Image or video pattern matchingProximity measures in feature spaces
• G06T 7/00 - Image analysis
• G06T 7/11 - Region-based segmentation
• G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints

Abstract

Disclosed in the present invention are: a pharmaceutical composition for preventing or treating fibrotic diseases, comprising hyaluronan and proteoglycan link protein 1 (HAPLN1) or a gene encoding same as an active ingredient; and a method for preventing or treating fibrotic diseases using the composition. According to the present invention, fibrosis of cells or tissues is prevented and inhibited such that the occurrence or progression of various kinds of diseases caused by fibrosis is fundamentally suppressed, and thus the diseases can be prevented or treated.

IPC Classes  ?

• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 43/00 - Drugs for specific purposes, not provided for in groups