Circassia Limited

United Kingdom

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IP Type
        Patent 39
        Trademark 14
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        World 35
        United States 11
        Canada 4
        Europe 3
Owner / Subsidiary
[Owner] Circassia Limited 40
Prosonix Limited 13
Date
2022 2
Before 2021 49
IPC Class
A61K 39/35 - Allergens 16
A61K 39/36 - Allergens from pollen 9
B01D 9/00 - Crystallisation 8
A61K 39/00 - Medicinal preparations containing antigens or antibodies 7
A61K 9/00 - Medicinal preparations characterised by special physical form 7
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NICE Class
05 - Pharmaceutical, veterinary and sanitary products 9
10 - Medical apparatus and instruments 7
09 - Scientific and electric apparatus and instruments 4
42 - Scientific, technological and industrial services, research and design 2
35 - Advertising and business services 1

1.

FENOLYTICS

      
Application Number 1661389
Status Registered
Filing Date 2022-03-30
Registration Date 2022-03-30
Owner Circassia Limited (United Kingdom)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments

Goods & Services

Software; software and hardware for diagnosing, monitoring, measuring, calculating, analysing and displaying airway inflammation and respiratory status; software and hardware for analysing, storing, organising, categorising, tracking, displaying and retrieving data regarding airway inflammation and respiratory status; software and hardware for analysing, storing, organising, categorising, tracking, displaying and retrieving data from medical devices. Medical devices; medical apparatus and instruments; medical apparatus for sampling of gases in human organs and for control of pulmonary functionality; medical devices for controlling the exhalation of oxygen in breath; medical devices being containers for the storage of exhaled breath samples; medical devices, namely, respiratory filters and nozzles for use in sampling exhalation; medical devices, namely, containers for sampling and storing of gas tests.

2.

FENOLYTICS

      
Serial Number 79340522
Status Registered
Filing Date 2022-03-30
Registration Date 2023-10-10
Owner Circassia Limited (United Kingdom)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments

Goods & Services

Computer hardware and recorded software sold as a unit for diagnosing, monitoring, measuring, calculating, analysing and displaying airway inflammation and respiratory status; Computer hardware and recorded software sold as a unit for analysing, storing, organising, categorising, tracking, displaying and retrieving data regarding airway inflammation and respiratory status; Computer hardware and recorded software sold as a unit for analysing, storing, organising, categorising, tracking, displaying and retrieving data from medical devices Medical apparatus for sampling of gases in human organs and for control of pulmonary functionality; medical devices for controlling the exhalation of oxygen in breath; medical devices being containers for the storage of exhaled breath samples; medical devices, namely, respiratory filters and nozzles for use in sampling exhalation for medical purposes; medical devices, namely, containers for sampling and storing of medical gas tests

3.

CIRCASSIA

      
Application Number 1567300
Status Registered
Filing Date 2020-10-23
Registration Date 2020-10-23
Owner Circassia Limited (United Kingdom)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments

Goods & Services

Software and hardware for diagnosing, monitoring, measuring, calculating, analysing and displaying airway inflammation and respiratory status; software and hardware for analysing, storing, organising, categorising, tracking, displaying and retrieving data regarding airway inflammation and respiratory status; software and hardware for analysing, storing, organising, categorising, tracking, displaying and retrieving data from medical devices. Medical devices; medical apparatus and instruments; medical apparatus for sampling of gases in human organs and for control of pulmonary functionality; medical devices for controlling the exhalation of oxygen in breath; medical devices being containers for the storage of exhaled breath samples; medical devices, namely, respiratory filters and nozzles for use in sampling exhalation; medical devices, namely, containers for sampling and storing of gas tests.

4.

CIRCASSIA

      
Serial Number 79300849
Status Registered
Filing Date 2020-10-23
Registration Date 2021-10-05
Owner Circassia Limited (United Kingdom)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments

Goods & Services

Computer hardware and recorded software sold as a unit for diagnosing, monitoring, measuring, calculating, analysing and displaying airway inflammation and respiratory status; computer hardware and recorded software sold as a unit for analysing, storing, organising, categorising, tracking, displaying and retrieving data regarding airway inflammation and respiratory status; computer hardware and recorded software sold as a unit for analysing, storing, organising, categorising, tracking, displaying and retrieving data from medical devices Medical apparatus for sampling of gases in human organs and for control of pulmonary functionality; medical devices for controlling the exhalation of oxygen in breath; medical devices being containers for the storage of exhaled breath samples; medical devices, namely, respiratory filters and nozzles for use in sampling exhalation; medical devices, namely, containers for sampling and storing of medical gas tests

5.

JAPANESE POLLEN ALLERGEN PEPTIDES FOR PREVENTING OR TREATING ALLERGY

      
Application Number GB2017050246
Publication Number 2017/134430
Status In Force
Filing Date 2017-02-01
Publication Date 2017-08-10
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hickey, Pascal
  • Laidler, Paul
  • Gliddon, Dan
  • Carniaux, Jean-Francois

Abstract

A polypeptide or a pharmaceutically acceptable salt thereof and pharmaceutical formulations of at least three polypeptidesor salts thereof are provided which may be used for preventing or treating allergy to Japanese Cedar and/or Japanese Cypress pollen.

IPC Classes  ?

  • A61K 39/36 - Allergens from pollen
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • A61P 37/08 - Antiallergic agents

6.

METHOD OF FORMING CONCENTRATED SOLUTION

      
Application Number GB2015052763
Publication Number 2016/046553
Status In Force
Filing Date 2015-09-24
Publication Date 2016-03-31
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Burns, John
  • Parikh, Dipesh

Abstract

The present invention relates to a method of forming a concentrated solution of first and second pharmacologically active ingredients which involves: providing a solid eutectic composition of the first and second pharmacologically active ingredients; providing a first solvent; and dissolving the eutectic composition in the first solvent; wherein the first and second pharmacologically active ingredients are independently selected from β2 agonists, muscarinic antagonists, anticholinergics, corticosteroids, methylxanthine compounds and salts, esters, polymorphs, hydrates or solvates thereof. A solution obtainable by this method is also described, along with an ampoule for a nebuliser and a pressurised metered dose inhaler comprising the solution. The solution is useful in the treatment of respiratory diseases.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 9/08 - Solutions
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
  • A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

7.

Process for making crystals

      
Application Number 14854750
Grant Number 10143991
Status In Force
Filing Date 2015-09-15
First Publication Date 2016-01-07
Grant Date 2018-12-04
Owner Circassia Limited (United Kingdom)
Inventor
  • Robinson, James
  • Ruecroft, Graham

Abstract

A process for preparing crystalline particles of an active principal in the presence of ultrasonic irradiation that comprises contacting a solution of a solute in a solvent in a first flowing stream with an anti-solvent in a second flowing stream causing the mixing thereof, wherein the flow rate ratio of the anti-solvent: solvent is higher than 20:1, and collecting crystals that are generated.

IPC Classes  ?

  • B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations
  • B01J 2/02 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
  • B01J 2/18 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus
  • B01J 19/18 - Stationary reactors having moving elements inside
  • B01D 9/00 - Crystallisation
  • C07J 31/00 - Normal steroids containing one or more sulfur atoms not belonging to a hetero ring

8.

Multi-Bri

      
Application Number 1280669
Status Registered
Filing Date 2015-09-28
Registration Date 2015-09-28
Owner Prosonix Limited (United Kingdom)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Pharmaceutical and medicinal preparations and substances. Medical apparatus and instruments; inhalers.

9.

SERIVEO

      
Application Number 1275694
Status Registered
Filing Date 2015-09-28
Registration Date 2015-09-28
Owner Circassia Limited (United Kingdom)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Pharmaceutical and medicinal preparations and substances. Medical apparatus and instruments; inhalers.

10.

XINIVEO

      
Application Number 1274737
Status Registered
Filing Date 2015-09-28
Registration Date 2015-09-28
Owner Prosonix Limited (United Kingdom)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Pharmaceutical and medicinal preparations and substances. Medical apparatus and instruments; inhalers.

11.

FELTOPIA

      
Application Number 1264184
Status Registered
Filing Date 2015-07-17
Registration Date 2015-07-17
Owner Circassia Limited (United Kingdom)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical and veterinary preparations and substances; pharmaceutical and veterinary preparations and substances for the testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; reagent kits for testing and diagnosing allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; vaccines.

12.

KATCLARI

      
Application Number 1263484
Status Registered
Filing Date 2015-07-10
Registration Date 2015-07-10
Owner Circassia Limited (United Kingdom)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical and veterinary preparations and substances; pharmaceutical and veterinary preparations and substances for the testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; reagent kits for testing and diagnosing allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; vaccines.

13.

FELIPEPTA

      
Application Number 014355961
Status Registered
Filing Date 2015-07-13
Registration Date 2015-12-09
Owner Circassia Limited (United Kingdom)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical and veterinary preparations and substances; pharmaceutical and veterinary preparations and substances for the testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; reagent kits for testing and diagnosing allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; vaccines.

14.

FELTOPIA

      
Application Number 014356001
Status Registered
Filing Date 2015-07-13
Registration Date 2015-12-09
Owner Circassia Limited (United Kingdom)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical and veterinary preparations and substances; pharmaceutical and veterinary preparations and substances for the testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; reagent kits for testing and diagnosing allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; vaccines.

15.

KATCLARI

      
Application Number 014343529
Status Registered
Filing Date 2015-07-08
Registration Date 2015-12-09
Owner Circassia Limited (United Kingdom)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical and veterinary preparations and substances; pharmaceutical and veterinary preparations and substances for the testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; reagent kits for testing and diagnosing allergies, autoimmune disease, transplant rejection or immunodeficiency disorders; vaccines.

16.

PHARMACEUTICAL COMPOSITIONS COMPRISING MULTI-COMPONENT CRYSTALLINE PARTICLES SUITABLE FOR USE IN INHALATION THERAPY

      
Application Number GB2014050233
Publication Number 2014/118532
Status In Force
Filing Date 2014-01-29
Publication Date 2014-08-07
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Burns, John
  • Parikh, Dipesh

Abstract

Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy and for delivery by oral or nasal inhalation are provided, wherein said compositions additionally comprise particles of at least one additional active agent. Also provided are methods of preparation of the compositions and their use in medicine.

IPC Classes  ?

  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/4015 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
  • A61K 31/4196 - 1,2,4-Triazoles
  • A61P 11/00 - Drugs for disorders of the respiratory system

17.

MULTI-COMPONENT CRYSTALLINE PARTICLES FOR INHALATION THERAPY

      
Application Number GB2014050231
Publication Number 2014/118530
Status In Force
Filing Date 2014-01-29
Publication Date 2014-08-07
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Burns, John
  • Parikh, Dipesh
  • Karki, Shyam

Abstract

Pharmaceutical Preparations Multi-component crystalline particles and compositions, methods for their preparation, their uses in inhalation therapy and inhaler devices containing said particles are provided, in particular particles comprising glycopyrrolate. The particles can be prepared substantially free of excipients and agents other than active agents or their precursors in the presence of ultrasonic irradiation in a process comprising contacting a solution in a first flowing stream with an anti-solvent in a re-circulating second flowing stream, causing the mixing thereof and collecting crystals that are generated.

IPC Classes  ?

  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/4015 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
  • A61K 31/4196 - 1,2,4-Triazoles
  • A61P 11/00 - Drugs for disorders of the respiratory system

18.

CIRCASSIA

      
Application Number 167801400
Status Registered
Filing Date 2014-05-22
Registration Date 2016-03-18
Owner Circassia Limited (United Kingdom)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

(1) Pharmaceutical preparations for testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection and immunodeficiency disorders; veterinary pharmaceutical preparations for testing, diagnosis and treatment of allergies, autoimmune disease, transplant rejection and immunodeficiency disorders; Vaccines for human and veterinary use; Surgical, medical and veterinary apparatus and instruments, namely, kits comprised of pharmaceutical preparations, reagents and chemicals for testing, diagnosing and treating allergies and other immunodeficiency disorders. (1) Pharmacological research services; Research and development in the pharmaceutical and biotechnology fields; Providing medical and scientific research information in the fields of pharmaceutical and clinical trials; Conducting clinical trials; information, advisory and consultancy services relating to the aforesaid.

19.

JAPANESE CEDAR PEPTIDE FOR PREVENTING OR TREATING ALLERGY

      
Application Number GB2013051733
Publication Number 2014/001820
Status In Force
Filing Date 2013-06-28
Publication Date 2014-01-03
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul
  • Hickey, Pascal
  • Larche, Mark

Abstract

A polypeptide which may be used for preventing or treating allergy to Japanese Cedar and/or Japanese Cypress pollen, is up to 30 amino acids in length, and comprises (I) the amino acid sequence: DLKIKLRRTIEAEGIP(SEQ ID NO: 1; Cry26); or(II)a T cell epitope-containing variant sequence which is a said amino acid sequence (I) having up to seven amino acid modifications, each of which is independently a deletion, substitution or insertion.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 39/36 - Allergens from pollen
  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

20.

ALTERNARIA PEPTIDES

      
Application Number GB2013051439
Publication Number 2013/179043
Status In Force
Filing Date 2013-05-30
Publication Date 2013-12-05
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul
  • Hickey, Pascal
  • Larche, Mark

Abstract

Pharmaceutical formulations,which may be used for preventing or treating allergy to moulds of the Alternaria and/or Cladosporiumgenus, comprising a pharmaceutically acceptable carrier or diluent and a polypeptide or a pharmaceutically acceptable salt thereof selected from at least three of: (a)a polypeptide comprising the amino acid sequence of WSWKIGPAIATGNT(Alt28; SEQ ID NO: 101) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; (b)a polypeptide comprising the amino acid sequence of KYRRVVRAGVKVAQTAR(Alt34A; SEQ ID NO: 107) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; (c) a polypeptide comprising the amino acid sequence of KYAGVFVSTGTLGGG (SEQ ID NO: 112) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; (d)a polypeptide comprising the amino acid sequence of AEVYQKLKALAKKTYGQ(Alt13A; SEQ ID NO: 83) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; (e)a polypeptide comprising the amino acid sequence of SLGFNIKATNGGTLD(Alt01A; SEQ ID NO: 60)or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; (f) a polypeptide comprising the amino acid sequence of SAKRMKVAFKLDIEK(Alt06; SEQ ID NO: 72) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; (g)a polypeptide comprising the amino acid sequence of DITYVATATLPNYCR(SEQ ID NO: 111) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; and (h)a polypeptide comprising the amino acid sequence of GWGVMVSHRSGET(Alt14;SEQ ID NO: 84) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof; wherein a T cell epitope-containing variant sequence of a said amino acid sequence is said amino acid sequence having up to seven amino acid modifications, each of which is independently a deletion, substitution or insertion, and each polypeptide is up to 30 amino acids in length.

IPC Classes  ?

  • C07K 14/37 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from fungi
  • A61K 39/35 - Allergens
  • A61P 37/08 - Antiallergic agents

21.

CLADOSPORIUM PEPTIDES

      
Application Number GB2013051440
Publication Number 2013/179044
Status In Force
Filing Date 2013-05-30
Publication Date 2013-12-05
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul
  • Hickey, Pascal
  • Larche, Mark

Abstract

Polypeptides which may be used for preventing or treating allergy to moulds of the Cladosporium and/or Alternaria genus, have up to 30 amino acids in length and comprise: (I) the amino acid sequence: (a) GGYKAAVRPTMLE (SEQ ID NO : 35; Cla35), (b) AE V YQKLK SLTKK (SEQ ID NO: 31; Clal6), (c) VAITYASRAQGAE (SEQ ID NO: 32; Cla25), (d) GHHFKERGTGSLVIT (SEQ ID NO: 33; Cla26), or (e) ANYTQTKTVSIRL (SEQ ID NO: 34; Cla29); or (II) a T cell epitope-containing variant sequence which is a said amino acid sequence (I) having up to six amino acid modifications, each of which is independently a deletion, substitution or insertion.

IPC Classes  ?

  • C07K 14/37 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from fungi
  • C12N 9/64 - Proteinases derived from animal tissue, e.g. rennin
  • A61K 39/35 - Allergens

22.

HYDROCHLORIDE SALT OF PEPTIDE AND ITS USE IN COMBINATION WITH OTHER PEPTIDES FOR IMMUNOTHERAPY

      
Application Number GB2013051201
Publication Number 2013/167897
Status In Force
Filing Date 2013-05-09
Publication Date 2013-11-14
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Laidler, Paul
  • Farkas, Imre

Abstract

The present invention relates to a hydrochloride salt of a peptide consisting of the sequence of CPAVKRDVDLFLT (SEQ ID NO: 1) as well as its combinations with other peptides for immunosuppressive purposes.

IPC Classes  ?

  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • A61K 39/35 - Allergens

23.

Peptides for vaccine against birch allergy

      
Application Number 13578888
Grant Number 09017689
Status In Force
Filing Date 2011-02-15
First Publication Date 2013-09-19
Grant Date 2015-04-28
Owner Circassia Limited (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul
  • Layton, Guy
  • Larche, Mark

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to birch, and in particular to optimal combinations of peptides for preventing or treating said allergy.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/35 - Allergens
  • A61K 39/36 - Allergens from pollen
  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

24.

EUTECTIC MIXTURE FOR PULMONARY ADMINISTRATION

      
Application Number GB2012051924
Publication Number 2013/021199
Status In Force
Filing Date 2012-08-08
Publication Date 2013-02-14
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Parikh, Dipesh

Abstract

This invention provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for delivery to the lung by inhalation. This invention also provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for the treatment of respiratory disease.

IPC Classes  ?

  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61K 9/00 - Medicinal preparations characterised by special physical form

25.

Grass peptides for vaccine

      
Application Number 13148024
Grant Number 08753644
Status In Force
Filing Date 2010-02-05
First Publication Date 2012-06-14
Grant Date 2014-06-17
Owner Circassia Limited (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul
  • Layton, Guy
  • Larche, Mark

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.

IPC Classes  ?

26.

PEPTIDES FOR VACCINES AGAINST BIRCH ALLERGY

      
Application Number GB2011000206
Publication Number 2011/098778
Status In Force
Filing Date 2011-02-15
Publication Date 2011-08-18
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Laidler, Paul
  • Layton, Guy
  • Larche, Mark

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to birch, and in particular to optimal combinations of peptides for preventing or treating said allergy.

IPC Classes  ?

27.

Process for improving crystallinity

      
Application Number 13054532
Grant Number 09637840
Status In Force
Filing Date 2009-07-20
First Publication Date 2011-06-23
Grant Date 2017-05-02
Owner
  • CIRCASSIA LIMITED (United Kingdom)
  • CIRCASSIA PHARMACEUTICALS PLC (United Kingdom)
  • CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Parikh, Dipesh
  • Hipkiss, David

Abstract

This invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.

IPC Classes  ?

  • B32B 5/16 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by features of a layer formed of particles, e.g. chips, chopped fibres, powder
  • C30B 29/60 - Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape characterised by shape
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • B01D 9/00 - Crystallisation
  • C30B 1/12 - Single-crystal growth directly from the solid state by pressure treatment during the growth

28.

Peptide with reduced dimer formation

      
Application Number 12673334
Grant Number 08551493
Status In Force
Filing Date 2008-08-15
First Publication Date 2011-05-26
Grant Date 2013-10-08
Owner Circassia Limited (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul

Abstract

The present invention relates to peptides which are formulated or engineered to prevent or reduce the formation of dimers.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C07K 2/00 - Peptides of undefined number of amino acidsDerivatives thereof
  • C07K 4/00 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof
  • C07K 5/00 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
  • C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
  • C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
  • C07K 17/00 - Carrier-bound or immobilised peptidesPreparation thereof

29.

PROCESS FOR IMPROVING CRYSTALLINITY

      
Application Number GB2010051762
Publication Number 2011/048412
Status In Force
Filing Date 2010-10-20
Publication Date 2011-04-28
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Parikh, Dipesh

Abstract

The invention provides a process for increasing the crystallinity of at least one solid material which is less than 100 % crystalline, comprising applying ultrasound to the substantially dry solid material.

IPC Classes  ?

  • B01D 9/00 - Crystallisation
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • B01B 1/00 - BoilingBoiling apparatus for physical or chemical purposes
  • A61K 9/00 - Medicinal preparations characterised by special physical form

30.

Peptide for vaccine

      
Application Number 12673412
Grant Number 08652485
Status In Force
Filing Date 2008-08-15
First Publication Date 2010-10-14
Grant Date 2014-02-18
Owner Circassia Limited (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Laidler, Paul
  • Larche, Mark

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/35 - Allergens
  • A61K 39/36 - Allergens from pollen
  • C07K 5/00 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
  • C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
  • C07K 17/00 - Carrier-bound or immobilised peptidesPreparation thereof

31.

Vaccine peptide combinations against cat allergy

      
Application Number 12602313
Grant Number 08551492
Status In Force
Filing Date 2008-05-30
First Publication Date 2010-09-23
Grant Date 2013-10-08
Owner Circassia Limited (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Larche, Mark
  • Kay, Anthony Barrington

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/35 - Allergens
  • A61K 39/36 - Allergens from pollen
  • C07K 2/00 - Peptides of undefined number of amino acidsDerivatives thereof
  • C07K 4/00 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof
  • C07K 5/00 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
  • C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
  • C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
  • C07K 17/00 - Carrier-bound or immobilised peptidesPreparation thereof

32.

GRASS PEPTIDES FOR VACCINE

      
Application Number GB2010000198
Publication Number 2010/089554
Status In Force
Filing Date 2010-02-05
Publication Date 2010-08-12
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Rod
  • Laidler, Paul
  • Layton, Guy
  • Larche, Mark

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.

IPC Classes  ?

  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
  • A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
  • A61K 39/36 - Allergens from pollen

33.

Process for making crystals

      
Application Number 12665019
Grant Number 09278323
Status In Force
Filing Date 2008-06-17
First Publication Date 2010-07-29
Grant Date 2016-03-08
Owner
  • CIRCASSIA PHARMACEUTICALS PLC (United Kingdom)
  • CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Robinson, James
  • Parikh, Dipesh

Abstract

A process for preparing an emulsion or a dispersion comprising crystalline particles of at least one active principal that comprises contacting a solution of at least one solute in a solvent or mixture of solvents in a first flowing stream with a non-solvent in a second flowing stream wherein the non-solvent and solvent are not miscible with each other, so as to form an emulsion or a dispersion. Super saturation is brought about by suitable means, and the emulsion or dispersion is subjected to ultrasonic irradiation to mediate crystal nucleation.

IPC Classes  ?

  • B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations
  • B01J 2/06 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
  • A61K 9/14 - Particulate form, e.g. powders
  • B01D 9/00 - Crystallisation
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • B01J 2/18 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

34.

AN APPARATUS AND PROCESS FOR PRODUCING CRYSTALS

      
Application Number GB2010050007
Publication Number 2010/079350
Status In Force
Filing Date 2010-01-05
Publication Date 2010-07-15
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Burns, John

Abstract

This invention provides an oscillating baffled reactor apparatus for preparing crystalline particles of at least one substance comprising: a reactor vessel; means for supplying a first flowing stream; means for oscillating fluid within the reactor vessel; a plurality of baffles; source of ultrasonic radiation; and means for collecting said particles.

IPC Classes  ?

  • B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
  • B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations
  • B01J 19/18 - Stationary reactors having moving elements inside

35.

COMPOSITIONS WITH REDUCED DIMER FORMATION

      
Application Number GB2009002767
Publication Number 2010/061193
Status In Force
Filing Date 2009-11-27
Publication Date 2010-06-03
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Laidler, Paul

Abstract

The present invention relates to the use of a non-reducing carbohydrate or carbohydrate derivative and at least one agent which inhibits dimer formation in a freeze-dried composition comprising at least one peptide that contains a free cysteine residue, to provide a freeze-dried composition with improved long-term storage stability.

IPC Classes  ?

  • A61K 9/19 - Particulate form, e.g. powders lyophilised
  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
  • A61K 39/35 - Allergens

36.

VACCINE COMPRISING AMB A 1 PEPTIDES FOR USE IN THE TREATMENT OF RAGWEED ALLERGY

      
Application Number GB2009001986
Publication Number 2010/018378
Status In Force
Filing Date 2009-08-14
Publication Date 2010-02-18
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Larche, Mark
  • Hafner, Roderick, Peter
  • Laidler, Paul

Abstract

The present invention relates to compositions for preventing or treating allergy to ragweed by tolerisation. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, Amb a 1. The invention also relates to products, vectors and formulations which may be used to provide polypeptides of the invention in combination. The invention further relates to in vitro methods for determining whether T cells recognize a polypeptide of the invention, and for determining whether an individual has or is at risk of a condition characterized by allergic symptoms in response to a ragweed allergen.

IPC Classes  ?

  • A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
  • A61K 39/36 - Allergens from pollen
  • C07K 7/04 - Linear peptides containing only normal peptide links
  • A61P 37/08 - Antiallergic agents
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
  • C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

37.

T-CELL ANTIGEN PEPTIDE FROM ALLERGEN FOR STIMULATION OF IL-10 PRODUCTION

      
Application Number GB2009001995
Publication Number 2010/018384
Status In Force
Filing Date 2009-08-14
Publication Date 2010-02-18
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Larche, Mark
  • Hafner, Roderick, Peter
  • Laidler, Paul

Abstract

A first or second polypeptide for use in a method of treating or preventing a disorder by tolerisation, wherein said method comprises administration of the first and second polypeptide; and wherein both first and second polypeptides: i) are of 7 to 30 amino acids in length; ii) comprise at least one MHC Class Il-binding T cell epitope; and iii) are a fragment of a protein allergen or a homologous variant of said fragment; wherein said first polypeptide induces the release of an amount of IL-10 that is greater than the amount of IL-10 released in response to the whole protein allergen from which the first polypeptide derives; wherein said disorder is characterised by an inappropriate immune response to the protein allergen from which the second polypeptide derives.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • C07K 7/04 - Linear peptides containing only normal peptide links
  • C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

38.

Process for making crystals

      
Application Number 12531322
Grant Number 09162160
Status In Force
Filing Date 2008-03-18
First Publication Date 2010-01-28
Grant Date 2015-10-20
Owner
  • CIRCASSIA PHARMACEUTICALS PLC (United Kingdom)
  • CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Robinson, James
  • Ruecroft, Graham

Abstract

A process for preparing crystalline particles of an active principal in the presence of ultrasonic irradiation that comprises contacting a solution of a solute in a solvent in a first flowing stream with an anti-solvent in a second flowing stream causing the mixing thereof, wherein the flow rate ratio of the anti-solvent: solvent is higher than 20:1, and collecting crystals that are generated.

IPC Classes  ?

  • B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations
  • B01D 9/00 - Crystallisation

39.

PROCESS FOR IMPROVING CRYSTALLINITY OF FLUTICASONE PARTICLES

      
Application Number GB2009050884
Publication Number 2010/007446
Status In Force
Filing Date 2009-07-20
Publication Date 2010-01-21
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Parikh, Dipesh
  • Hipkiss, David

Abstract

This invention provides a process for increasing the crystallinity of at least one solid material comprising a fluticasone compound which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.

IPC Classes  ?

  • B01D 9/00 - Crystallisation
  • C30B 7/00 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • B01D 1/18 - Evaporating by spraying to obtain dry solids
  • F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
  • F26B 3/12 - Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray

40.

PROCESS FOR IMPROVING CRYSTALLINITY

      
Application Number GB2009050885
Publication Number 2010/007447
Status In Force
Filing Date 2009-07-20
Publication Date 2010-01-21
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Parikh, Dipesh
  • Hipkiss, David

Abstract

This invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.

IPC Classes  ?

  • B01D 9/00 - Crystallisation
  • C30B 7/00 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • B01D 1/18 - Evaporating by spraying to obtain dry solids
  • F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
  • F26B 3/12 - Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray

41.

PEPTIDES FROM FACTOR VIII

      
Application Number GB2009000187
Publication Number 2009/095646
Status In Force
Filing Date 2009-01-23
Publication Date 2009-08-06
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor Hafner, Roderick, Peter

Abstract

The present invention relates to compositions comprising peptides for preventing or treating the development of inhibitors in patients with haemophilia, in particular certain peptides and / or peptide fragments derived from factor VIII.

IPC Classes  ?

  • A61K 38/37 - Factors VIII
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
  • C07K 14/755 - Factors VIII
  • A61P 7/04 - AntihaemorrhagicsProcoagulantsHaemostatic agentsAntifibrinolytic agents
  • A61P 37/00 - Drugs for immunological or allergic disorders

42.

UMAX

      
Application Number 142980300
Status Registered
Filing Date 2009-03-04
Registration Date 2012-03-07
Owner Prosonix Limited (United Kingdom)
NICE Classes  ?
  • 35 - Advertising and business services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

(1) Treating liquids, droplets of liquid, and particles with ultrasonic waves to modify their properties in the pharmaceutical industry and in the chemical industry; technical consultancy services in the field of ultrasonic treatment of liquids, droplets of liquid, and particles to modify their properties in the pharmaceutical industry and in the chemical industry.

43.

PEPTIDE WITH REDUCED DIMER FORMATION

      
Application Number GB2008002779
Publication Number 2009/022155
Status In Force
Filing Date 2008-08-15
Publication Date 2009-02-19
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Laidler, Paul

Abstract

The present invention relates to peptides which are formulated or engineered to prevent or reduce the formation of dimers.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

44.

PEPTIDE WITH MULTIPLE EPITOPES

      
Application Number GB2008002778
Publication Number 2009/022154
Status In Force
Filing Date 2008-08-15
Publication Date 2009-02-19
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Larche, Mark

Abstract

The present invention relates to peptides comprising multiple MHC Class II-binding T cell epitopes for tolerisation therapy.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C07K 4/06 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof from fungi
  • C07K 4/10 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof from plants
  • C07K 4/12 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof from animalsPeptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof from humans
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof

45.

PEPTIDES FOR DESENSIBILIZATION AGAINST ALLERGENS

      
Application Number GB2008002780
Publication Number 2009/022156
Status In Force
Filing Date 2008-08-15
Publication Date 2009-02-19
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Laidler, Paul
  • Larche, Mark

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

46.

PEPTIDE WITH IMPROVED SOLUBILITY

      
Application Number GB2008002781
Publication Number 2009/022157
Status In Force
Filing Date 2008-08-15
Publication Date 2009-02-19
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Laidler, Paul

Abstract

The present invention relates to soluble peptides comprising T cell epitopes and methods for engineering insoluble peptides comprising T cell epitopes to improve solubility.

IPC Classes  ?

47.

PROCESS FOR MAKING CRYSTALS

      
Application Number GB2008050452
Publication Number 2008/155570
Status In Force
Filing Date 2008-06-17
Publication Date 2008-12-24
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Ruecroft, Graham
  • Robinson, James
  • Parikh, Dipesh

Abstract

A process for preparing an emulsion or a dispersion comprising crystalline particles of at least one active principal that comprises contacting a solution of at least one solute in a solvent or mixture of solvents in a first flowing stream with a non-solvent in a second flowing stream wherein the non-solvent and solvent are not miscible with each other, so as to form an emulsion or a dispersion. Super saturation is brought about by suitable means, and the emulsion or dispersion is subjected to ultrasonic irradiation to mediate crystal nucleation.

IPC Classes  ?

  • B01D 9/00 - Crystallisation
  • B01J 2/02 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
  • B01J 2/18 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets

48.

VACCINE PEPTIDE COMBINATIONS AGAINST CAT ALLERGY

      
Application Number GB2008001827
Publication Number 2008/145998
Status In Force
Filing Date 2008-05-30
Publication Date 2008-12-04
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick, Peter
  • Larche, Mark
  • Kay, Anthony, Barrington

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • A61P 37/08 - Antiallergic agents
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof

49.

VACCINE PEPTIDE COMBINATIONS AGAINST CAT ALLERGY

      
Application Number GB2008001833
Publication Number 2008/146003
Status In Force
Filing Date 2008-05-30
Publication Date 2008-12-04
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Larche, Mark
  • Kay, Anthony Barrington

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • A61P 37/08 - Antiallergic agents
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof

50.

PROGNOSTIC ASSAY FOR DETERMINING T CELL RESPONSE TO HLA ANTIGENS AND USE THEREOF IN FIELD OF TISSUE TRANSPLANTATION

      
Application Number GB2008001614
Publication Number 2008/139163
Status In Force
Filing Date 2008-05-09
Publication Date 2008-11-20
Owner
  • CIRCASSIA LIMITED (United Kingdom)
  • THE UNIVERSITY OF BIRMINGHAM (United Kingdom)
Inventor Ball, Simon

Abstract

The invention provides an in vitro method of determining whether an individual is at risk of, or undergoing, graft damage or rejection of immune origin and/or damage of immune origin to non-graft tissue using polypeptides derived from a major histocompatibility complex (MHC) class I human leukocyte antigen (HLA), such as HLA-A2, and derivatives or analogues thereof.

IPC Classes  ?

  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
  • C07K 14/705 - ReceptorsCell surface antigensCell surface determinants

51.

PROCESS FOR MAKING CRYSTALS

      
Application Number GB2008050191
Publication Number 2008/114052
Status In Force
Filing Date 2008-03-18
Publication Date 2008-09-25
Owner PROSONIX LIMITED (United Kingdom)
Inventor
  • Robinson, James
  • Ruecroft, Graham

Abstract

A process for preparing crystalline particles of an active principal in the presence of ultrasonic irradiation that comprises contacting a solution of a solute in a solvent in a first flowing stream with an anti-solvent in a second flowing stream causing the mixing thereof, wherein the flow rate ratio of the anti- solvent: solvent is higher than 20:1, and collecting crystals that are generated.

IPC Classes  ?

  • B01J 2/02 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
  • B01J 2/18 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus
  • A61K 9/00 - Medicinal preparations characterised by special physical form

52.

PROCESS FOR MAKING CRYSTALS VIA ULTRASONIC IRRADIATION OF A CLOSED LOOP

      
Document Number 02680105
Status In Force
Filing Date 2008-03-18
Grant Date 2016-05-17
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Robinson, James
  • Ruecroft, Graham

Abstract

A process for preparing crystalline particles of an active principal in the presence of ultrasonic irradiation that comprises contacting a solution of a solute in a solvent in a first flowing stream with an anti-solvent in a second flowing stream causing the mixing thereof, wherein the flow rate ratio of the anti- solvent: solvent is higher than 20:1, and collecting crystals that are generated.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • B01J 2/02 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
  • B01J 2/18 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

53.

VACCINE PEPTIDE COMBINATIONS AGAINST CAT ALLERGY

      
Document Number 02689260
Status In Force
Filing Date 2008-05-30
Grant Date 2023-02-28
Owner CIRCASSIA LIMITED (United Kingdom)
Inventor
  • Hafner, Roderick Peter
  • Larche, Mark
  • Kay, Anthony Barrington

Abstract

The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides.

IPC Classes  ?

  • A61K 39/35 - Allergens
  • A61P 37/08 - Antiallergic agents
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof