Abstract

Embodiments of the present disclosure provide for biosensors that include a material such as polydiacetylene (PDA) material, where the material is used for detection of a microbe or microbial product present in a fluid present in the container. Embodiments of the present disclosure provide for containers, or structures used in conjunction with the containers, that include a polydiacetylene (PDA) material, where the PDA material is used for detection of a microbe or microbial product present in a fluid present in the container. In an embodiment, a change of PDA color (e.g., blue to red) indicates detection of the microbe or microbial product in the fluid within the container. In an embodiment, the PDA material can be selected and/or the container or structure designed so that only certain types of microbes can be detected or so that a plurality of types of microbes is detected.

IPC Classes  ?

• C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
• C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms

Abstract

In one embodiment, a solution container includes a body adapted to store a solution, a nozzle through which the solution can exit the body, and a biosensor material integrated with the container, wherein the biosensor material has a first color when it has not been exposed to a contaminant but turns a second color when it comes into contact with a contaminant.

IPC Classes  ?

• A61J 1/05 - Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids
• G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
• G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
• B65D 1/08 - Bottles or similar containers with necks or like restricted apertures, designed for pouring contents adapted to discharge drops
• A61M 35/00 - Devices for applying media, e.g. remedies, on the human body

Abstract

Provided herein is a composition for detection of a microbial product in a sample comprising a polydiacetylene (PDA) and a packaging polymer, wherein the sample contacts the PDA and a change of PDA color indicates detection. Also provided herein are methods of making a packaging material comprising a PDA and methods of using the composition for detection of a microbial product in a sample.

IPC Classes  ?

• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
• C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor