Abstract

The present invention relates to a method for cultivation of stem cells, and to a cell culture system for cultivating stem cells. Stem cells are cultivated in a growth medium including a predetermined concentration of oxide nanoparticles. In order to regulate cell growth, the concentration of the oxide nanoparticles is predetermined to influence the proliferative activity of the stem cells.

IPC Classes  ?

• A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• C12N 5/0775 - Mesenchymal stem cells; Adipose-tissue derived stem cells

Abstract

The invention relates to new epoxy compositions, suitable for bonding, scaling and repairing materials, which may be used also for household and medical purposes, due to their improved sanitary and hygienic properties. The main problem solved by the new epoxy compositions resides in that it is substantially reduced the release of volatile organic compounds (VOC), possessing harmful and toxic effects, essentially admixing the epoxy resin with a powder of bentonite intercalated by ions of (Ce3+) and with a size of the particles of no more than 200 nm.

IPC Classes  ?

• C08K 9/02 - Ingredients treated with inorganic substances
• C08L 63/00 - Compositions of epoxy resins; Compositions of derivatives of epoxy resins
• C09C 3/06 - Treatment with inorganic compounds

Abstract

The invention concerns nanotechnology, in particular a process for obtaining boron-silicon containing nanoparticles with a high percentage of boron. The process of obtaining boron-silicon-containing nanoparticles consists in filling a flow reactor with a reactive gas mixture containing silicomethane (SiH4) a reagent «B» which is a salt of boron and a buffer gas and in the induction of the pyrolysis of the gas mixture by continuous radiation of CO2-laser, under pressure of the gas mixture below atmospheric one. At realization of the present invention, boron-silicon containing nanoparticles are obtained, with a high content of boron and a size of 5-30 nm, suitable for the boron neutron capture therapy.

IPC Classes  ?

• C01B 35/04 - Metal borides

Abstract

A method is described to evaluate in vitro the biological effect of bactericidal inorganic nanoparticles on the cellular system of a living organism, with the aim to state the possibility of using them in the pharmaceutical, medical, cosmetic industry. The method has essentially identified a set of biologic indexes, which must be determined on primary cells cultures of multipotent mesenchymal stromal cells (also called mesenchymal stem cells, MSC) separated from stromal-vascular fraction of human adipose tissue and on mononuclear cells-lymphocytes separated from human peripheral blood, both cultures containing the bactericidal inorganic nanoparticles. The indexes (such as cell viability (cytotoxicity), function of mitochondria, production of reactive oxygen species (ROS), state of lysosomal compartment, necrosis and apoptosis, intracellular accumulation of nanoparticles) are evaluated comprehensively, in comparison with the corresponding indexes obtained in the absence of the nanoparticles in the cells cultures.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Abstract

The invention concerns new compositions which imitates intraarticular liquid and thus can be introduced into an articulate cavity for replacement or correction of an intraarticular liquid lacking or pathologically modified. The new compositions consist essentially of water solutions of polyvinylpirrolidone and of an additive having antimicrobic activity, constituted by silicon nanoparticles modified with silver. The rheological properties of the new compositions can be improved by adding a water solution of sodium salt of hyaluronic acid.

IPC Classes  ?

• A61K 31/728 - Hyaluronic acid
• A61K 31/79 - Polymers of vinyl pyrrolidone
• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 33/38 - Silver; Compounds thereof
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Abstract

The invention relates to medicine and medical technology, namely to a method of formation of a biocompatible coating on the surface of implants used in reconstructive surgery for replacement of bone tissues. The disclosed method of formation of a nanostructured biocompatible coating on surfaces of implants consists in deposition of a film of polysilicon on the surface of the implant in a reactor. The obtained film of polysilicon is etched chemically for formation of a nanostructured near-surface layer of porous polysilicon. Etching of the film of polysilicon is carried out by immersion of the implant into a water solution containing a mix of tetrafluoroboric acid, nitric acid and an ammonium salt surfactant, with subsequent washing of the implant with deionized water and drying. Technological applications of the method of formation of a biocompatible coating by obtaining a nanostructured layer of porous polysilicon on surfaces of implants, without dependence from materials used for their manufacturing and from their design features, are extended by the present invention.

IPC Classes  ?

• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 27/56 - Porous or cellular materials

Abstract

The invention concerns hygiene, sanitary and medicine, in particular concerns a method for evaluating the influence on safety and toxicity of a polymeric material of a nano-structured bentonite (in particular montmorillonite) intercalated with ions of metals and admixed with it. The method consists essentially in admixing the polymer with the intercalated, nano-structured bentonite, activating and stabilizing the mixture with ultraviolet rays radiation, heating the activated samples, collecting the released gases and identifying them by gas-chromatographic analysis. The modified properties of the new composition are deduced by comparison of its analysis with the same analysis performed on a known mixture of the same polymer with the same bentonite, without metals intercalation.

IPC Classes  ?

• C08J 3/28 - Treatment by wave energy or particle radiation
• C08K 9/04 - Ingredients treated with organic substances
• C08K 9/02 - Ingredients treated with inorganic substances
• A01N 25/12 - Powders or granules
• G01N 1/40 - Concentrating samples

Abstract

The invention concerns manufacture of paint and varnish materials, in particular, structures of paints with heat-insulating and fireproof properties on surfaces of products manufactured from various constructional materials. The composition of the paints with heat-insulating and fireproof properties comprises a binding agent on the basis of a polymeric matrix in organic solvent, a filler as a mineral component, a fire retardant additive, a modifying additive as ceramic and-or glass microspheres with diameter of 20-150 microns and organic solvent. An additional mineral component on the basis of the bentonite powder intercalated by ions of cobalt (Co2+) or ions of cerium (Ce3+) or a mix of the mentioned powders at their ratio as 1 ÷ 1 (weight parts) is embedded in the structure of the paints. The protective coatings realized with the paints according to the invention have an improved resistance to oxidation reactions under heating, improved fire resistance, improved ecological safety and also bactericidal properties.

IPC Classes  ?

• C09D 5/00 - Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes

Abstract

The invention concerns new compositions on the base of polyurethanes, in particular, polyurethane systems intended for manufacturing elastic products, preferably, for medical purposes, such as, orthopedic antibedsore mattresses, seats-pillows, anatomic pillows, insoles-instep supports, orthopedic corsets, kneecaps, bandage products, footwear for various kinds of defects of foots and the like. Also improved polyurethane wound dressings can be produced. The new modified polyurethanes have improved sanitary and hygienic properties which render them specifically suitable for the claimed uses. The polyurethane system of the invention, with improved sanitary and hygienic properties, contains a polyol compound (component А), a isocyanate compound (component В) and a mineral agent (С) dispersed into the polyol compound (component А). The mineral agent (C) consists of a mix of nanostructured powders of bentonite intercalated by ions of silver(Ag+) and ions of cerium (Ce3+ ), in a ratio between them of 1 : (5-10) parts by weight. The articles produced with the new polyurethane system have clearly improved characteristics in so far as suppression of growths of microorganisms and preventing evolution of volatile toxic organic compounds are concerned.

IPC Classes  ?

• C08G 18/48 - Polyethers
• C08G 18/76 - Polyisocyanates or polyisothiocyanates cyclic aromatic
• A01N 59/06 - Aluminium; Calcium; Magnesium; Compounds thereof

Abstract

The invention concerns medicine and can be used to manufacture liquid compositions for external application, possessing antimicrobic properties and intended for preventive maintenance and treatment of diseases of integuments of people, for treatment of wounds and ulcers and for stimulation of regeneration and healing of wound surfaces in the syndrome of diabetic foot. The composition for preventive maintenance and care of diabetic foot comprises a film-forming substance, an antimicrobic agent in polar solvent and a locally anesthetic substance. The new compositions additionally contain a second antimicrobic agent on the basis of a mix of nano structured powders of bentonite intercalated by ions of silver (Ag+) and ions of cerium (Ce3+). The use of the new compositions according to the present invention, in preventive maintenance and treatment of the effects of the syndrome of diabetic foot, has promoted suppression of the microbic infection in wounds, acceleration of regeneration and healing of integuments of patients.

IPC Classes  ?

• A61K 9/70 - Web, sheet or filament bases
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61K 33/38 - Silver; Compounds thereof
• A61K 33/24 - Heavy metals; Compounds thereof

Abstract

Ointment for preventive treatment of diabetic foot which contains: as a carrier a hydrophilic water-soluble polymer, preferably consisting of a mix of polyethylene oxide 1500 and polyethylene oxide 400; as a first antiseptic agent an organic ammonium compound, preferably polyhexanide as a water solution with polyethylene glycol 4000; as a second antiseptic agent a nanostructured powder of bentonite intercalated by ions of silver Ag+ and/or cerium Се3+. The ointment can also contain 1,5-3,0% of carbamide.

IPC Classes  ?

• A61K 9/06 - Ointments; Bases therefor
• A61K 31/785 - Polymers containing nitrogen
• A61K 33/24 - Heavy metals; Compounds thereof
• A61K 33/38 - Silver; Compounds thereof
• A61K 47/02 - Inorganic compounds
• A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
• A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

The invention concerns the area of medicine, hygiene, cosmetology and provides products which can be used as a preventive bactericidal enamel for nail treatment. The preventive bactericidal polishes for treatment of nails of the invention contain a water-soluble film-forming substance, a bactericidal agent and a polar solvent. Powders of bentonite are used as the bactericidal agent. Bentonite is nanostructured up to a size of the particles of no more than 150 nm and is intercalated by ions of metals Ag+ or/and Cu2+ and Zn2+. The bentonite containing the metal ions is introduced in a preliminarily prepared emulsion of the film-forming substance, as 4 - 10 % hydrosol. The nail polish of the invention has the following ratio of components, in % b.w.: film-forming substance 1,0 - 10,0; bactericidal agent 0,2 - 1,5; polar solvent the rest. By realization of the invention effective protection of treated nails against a wide spectrum of bacteria and funguses is provided, with polishes with a low cost of manufacture. The polish can be used for treating nails and nail platens, for preventive avoidance and treatment of superficial mycosises and inflammatory processes.

IPC Classes  ?

• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61K 8/26 - Aluminium; Compounds thereof
• A61K 8/27 - Zinc; Compounds thereof
• A61K 8/34 - Alcohols
• A61K 8/73 - Polysaccharides
• A61Q 3/02 - Nail coatings
• A61Q 17/00 - Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
• A61K 33/30 - Zinc; Compounds thereof
• A61K 33/34 - Copper; Compounds thereof
• A61K 33/38 - Silver; Compounds thereof
• A61K 47/02 - Inorganic compounds
• A61P 31/04 - Antibacterial agents
• A61P 31/10 - Antimycotics
• C01B 33/26 - Aluminium-containing silicates

Abstract

The invention concerns the area of hygiene and sanitation, namely concerns compositions for processing of woven materials to the end of disinfecting the products from them. The compositions for antiseptic processing of woven materials contain 0,5-2% alcoholic solution of a block-copolymer on the basis of polydimethylsiloxane and polyurethane, with viscosity from 10000 up to 45000 Pa-s at 110°C. Biocide on the basis of a nanostructured powder of bentonite intercalated by ions of Ag+ or/and Cu2+ is injected into the mentioned solution. The essential element of novelty is that the compositions contain a nanostructured powder of bentonite intercalated by ions of cerium (Ce3+) at the ratio of the named powder of bentonite to the powder of bentonite intercalated by ions of Ag+ or/and Cu2+, as (0,001÷0,01) : 1 (parts by weight). A mix of bentonite powders at the ratio of the named mix to a block-copolymer, as (0,5-1) : 1 (parts by weight) is used on masses of dry woven materials, in an amount of 0.5-1.5 mass %. The compositions according to the invention provide an effective, prolonged antiseptic action to woven materials and products from them.

IPC Classes  ?

• A01N 25/08 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
• A01N 25/24 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
• A01N 59/20 - Copper
• A61K 33/24 - Heavy metals; Compounds thereof
• A61K 33/34 - Copper; Compounds thereof
• A61K 33/38 - Silver; Compounds thereof
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
• D06M 11/65 - Salts of oxyacids of nitrogen
• D06M 11/79 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof with silicon dioxide, silicic acids or their salts
• D06M 15/564 - Polyureas, polyurethanes or other polymers having ureide or urethane links; Precondensation products forming them
• D06M 15/643 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds containing silicon in the main chain
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• D06M 16/00 - Biochemical treatment of fibres, threads, yarns, fabrics or fibrous goods made from such materials, e.g. enzymatic

Abstract

0547PTWO 16 SCANNING PROBE MICROSCOPE WITH NANOTOME Abstract The device is intended for analysis of samples (8) after modification of their surface. The scanning probe microscope with nanotome comprises a base element (1) on which are installed a holder of a puncheon (2) with a puncheon (3), associated with a first drive (4), a holder of a sample (7), in which it is possible to fix a sample (8), associated with a second drive (9), and a scanning unit (14) having an opportunity of association with the sample (8). The first drive (4) is made in one-coordinate type (coordinate Y). It moves a puncheon (3) on the direction aside the sample (8). A second drive (9) is made in one-coordinate type (coordinate X). It moves the holder (7) with the sample (8) perpendicularly to coordinate Y. There is a variant in which a wear-resistant antifriction coating (113) is deposited on the surface of the puncheon (mainly a knife). The offered invention increases accuracy of measurement and expands functionalities of the device.

IPC Classes  ?

• G01Q 30/10 - Thermal environment
• G01Q 30/16 - Vacuum environment
• G01Q 30/20 - Sample handling devices or methods

Abstract

The invention concerns the area of medicine, namely bandages for treatment of purulent and infected wounds, trophic ulcers and for preventive avoidance of suppurations of infected wounds. The wound bandage with antimicrobic properties contains a textile carrier on the basis of dialdehydecellulose (DAC) with an immobilized proteolytic enzyme and an incorporated antimicrobic preparation. A nanostructured powder of bentonite intercalated by ions of metals Ag+ or/and Cu2+, or/and Zn2+ is used as the antimicrobic preparation. The wound bandage possesses high antimicrobic properties in respect to a wide spectrum of gram-positive and gram-negative bacteria, for processing and treatment of wounds with characteristics of a pyoinflammatory process of various etiologies. Synergic interaction of biological and mineral components, used in the composite structure of the wound bandage of the invention, improves medical properties of dressings.

IPC Classes  ?

• A61L 15/18 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
• A61L 15/38 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing enzymes
• A61L 15/44 - Medicaments
• A61L 15/46 - Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria

Abstract

The invention concerns the production of toilet soap with antimicrobic properties, which can be used both for medical and household purposes. The toilet soap contains a soap basis, functional additives and, as the antimicrobic agent, nanoparticles of a bentonite powder intercalated by ions of Ag+ or/and by ions of Cu2+ obtained by modification of bentonite with water solutions of silver nitrate and/or copper sulphate. Bentonite is preliminarly enriched with cations of Na+, by processing it with a solution of an inorganic salt of sodium and subsequent cleaning. Size of the particles of bentonite powder is no more than 150 nm. The toilet soap contains also, as an essential component, polyvinylpyrrolidone. The soap provides prolonged antimicrobic protection of the skin.

IPC Classes  ?

• C11D 9/18 - Water-insoluble compounds
• C11D 9/22 - Organic compounds
• C11D 3/37 - Polymers
• C11D 3/12 - Water-insoluble compounds
• C11D 3/48 - Medicinal or disinfecting agents
• A61K 8/26 - Aluminium; Compounds thereof

Abstract

The invention concerns a method for stabilizing polymers by admixing them, in fluid form, with an inhibitor of degradation consisting of nanoparticles of a layered mineral clay, preferably montmorillonite, intercalated by metal ions, preferably ions of cerium (Ce3+). Admixture is performed through application of ultrasounds, followed by a treatment under vacuum and by a curing treatment at a raised temperature of no more than 110°C.

IPC Classes  ?

• C08K 9/02 - Ingredients treated with inorganic substances

Abstract

Hygienic products such as hygienic towels, hygienic napkins, pampers and the like comprising at least one layer of adsorbing dry cellulose mass, previously treated with a water system of biocide consisting of nanoparticles of a bentonite powder intercalated by ions of silver and/or copper and also containing a copolymer on the basis of a hydrolyzed vegetal protein, whose ending or lateral amino groups are linked with silanol groups or polyvinylpirrolidone. The new products may contain also a superabsorbing layer on the basis of sodium polyacrylate or of a copolymer of polyacrilamide.

IPC Classes  ?

• A61L 15/18 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
• A61L 15/32 - Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
• A61L 15/44 - Medicaments

Abstract

The invention concerns a method for antiseptic processing of the surface of a product made of organosilicon rubbers with molecular weight 2⋅105-6⋅105, said method consisting in a two stages formation of an antiseptic coating on said surface of said product: (a) at a first stage said surface is modified by treatment in low-temperature oxygen plasma at high-frequency electromagnetic radiation; and (b) at a second stage the modified surface is processed applying on it an antiseptic preparation containing: a biocide, which is a nanodispersed powder of bentonite intercalated by ions of silver or/and copper; a fluoroacrylic polymeric binding agent, wherein said binding agent is dissolved in a mixture of fluoroalkylethers. The method provides the formation of a coating having effective antiseptic and operational properties especially when the coating is applied on the surface of small orthopedic devices such as foot-correctors, insoles, heel pads, etc..

IPC Classes  ?

• A01N 25/10 - Macromolecular compounds
• A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
• A01N 59/16 - Heavy metals; Compounds thereof
• A01N 59/20 - Copper
• B29C 59/14 - Surface shaping, e.g. embossing; Apparatus therefor by plasma treatment
• A01P 1/00 - Disinfectants; Antimicrobial compounds or mixtures thereof
• B05D 3/14 - Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by electrical means
• B05D 7/24 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials for applying particular liquids or other fluent materials

Abstract

A process for the production of biocides possessing fungicidal and bactericidal properties is described wherein bentonite is activated with ions of sodium and the obtained intermediate product is intercalated by ions of metals of bactericidal action such as Ag+, Cu2+, Zn2+ by reaction in water solutions of inorganic salts of these metals, under the action of ultrasounds having a frequency of 20-50 Khz and intensity of 10-100 WT/cm2.

IPC Classes  ?

• A01N 25/08 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
• A01N 25/12 - Powders or granules
• A01N 59/16 - Heavy metals; Compounds thereof
• A01N 59/20 - Copper
• A01P 1/00 - Disinfectants; Antimicrobial compounds or mixtures thereof
• A01N 55/10 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing silicon

Abstract

The invention concerns antiseptic ointments for external application comprising, as a basis, pharmaceutical Vaseline or a mix of pharmaceutical Vaseline with lanoline, and, as the antiseptic agent, a dispersed bentonite powder intercalated by one or more metal ions selected in the group consisting of Ag+, Cu2+, Zn2+. In addition the ointment contains an etheric vegetable oil. More precisely the active antiseptic agent may be: a dispersed bentonite powder intercalated by ions of Ag+ or by ions of Cu2+ or by a mix of said bentonites. According to an anternative the antiseptic dispersed bentonite powder may be intercalated by ions of Ag+ and Zn2+ or by ions of Cu2+ and Zn2+ or by ions of Ag+, Cu2+ and Zn2+. In any case the total content of metals in the composition of ointment is comprised between 0,05-0,5%. The ointments according to the invention are biologically compatible with various integuments of humans and animals and provide a prolonged antiseptic action at low expenses.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A01N 59/20 - Copper
• A01P 1/00 - Disinfectants; Antimicrobial compounds or mixtures thereof
• A01N 25/08 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
• A01N 25/24 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/06 - Ointments; Bases therefor
• A61K 9/08 - Solutions
• A61K 33/30 - Zinc; Compounds thereof
• A61K 33/34 - Copper; Compounds thereof
• A61K 33/38 - Silver; Compounds thereof
• A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

Abstract

The invention refers to a method of treating thready materials, especially useful for medical uses, such as production of sutures and the like. The method essentially consists in impregnating a thread of fibres with a solution of collagen containing an antiseptic component consisting of a nanodispersion of bentonite powders modified by intercalation of ions of Ag+ and/or Cu2+ and successively drying. The amount of said metals in the bentonite powder is of 2-8% by weight. The ratio between the ions of Ag+ and Cu2+, when both present, is of 1 : (0,3-0,5). The threads obtained have prolonged antimicrobic properties versus a wide spectrum of gram-positive and gram-negative microorganisms and a decreased toxicity. Moreover they have improved absorpion capacity.

IPC Classes  ?

• A61L 17/00 - Materials for surgical sutures or for ligaturing blood vessels
• A61L 17/08 - At least partly resorbable materials of animal origin, e.g. catgut, collagen

Abstract

This invention concerns biocides possessing fungicidal and bactericidal properties which can be used in construction, medicine and other various areas of technics. A nanostructural composition of biocide is realized from nanoparticles of bentonite powders intercalated by ions of Zn2+ and ions of Ag+ and/or ions of Cu2+. The biocides according to the invention are prepared starting from bentonite poweder which is preliminarly enriched with cations of Na+, then treated with 10-20% solutions of inorganic salts of Zn (preferably zinc chloride or zinc sulfate ZnSO4), and from bentonite powders preliminarly enriched with cations of Na+ and then treated with 10-20% solutions of inorganic salts of at least one ion selected in the group consisting of Ag+ ions (preferably silver nitrate) and Cu2++ ions (preferably copper sulfate). The powders of bentonite, intercalated with the Zn2+, Ag+ and/or Cu2+ ions, are cleaned from acid anions and Na+ salts, and dispersed into nanoparticles mainly of no more than 70nm. The biocide compositions according to the invention, contain the given components in the ratios by weight hereinafter indicated: nanoparticles intercalated by ions of Ag+ : nanoparticles intercalated by ions of Zn2+as 1 : (0,2 -0,8); or nanoparticles intercalated by ions of Ag+ : nanoparticles intercalated by ions of Zn2+ : nanoparticles intercalated by ions of Cu2+ as 1 : (0,2 -0,8) : (0,2- 0,5); or nanoparticles intercalated by ions of Zn2+ : nanoparticles intercalated by ions of Cu2+ as 1 : (0,2 -0,5).

IPC Classes  ?

• A01N 25/14 - Powders or granules wettable
• A01N 59/16 - Heavy metals; Compounds thereof
• A01N 59/20 - Copper
• A01P 1/00 - Disinfectants; Antimicrobial compounds or mixtures thereof
• A01P 3/00 - Fungicides