Abstract

The present invention is directed to method of determining whether a subject is at risk of developing insulin resistance, particularly for advance alert of T2D and or CVD onset in obese and non-obese subject, by detecting the branched-chain amino acids (BCAAs) present in an urine sample (uBCAAs) of the subjects. The present invention also relates to a method for determining the need of a dietary/nutritional supplement for a subject involving said uBCAAs biomarkers. Finally, the invention is directed to kit comprising the biochemical network allowing the uBCAAs detection and process for the preparation of said biochemical networks as diagnostic biomarker.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
• G01N 1/34 - PurifyingCleaning

Abstract

The invention relates to a method for identifying an emotion or a group of emotions felt by a subject after olfactory stimulation, from saliva samples of said subject implementing salivary biomarkers signature. In a second aspect, the invention also relates to a method for evaluating the capacity of an olfactory stimulus to provoke in a subject a desired emotion or group of emotions. The invention finally relates to the use of kit in the context of the present invention.

IPC Classes  ?

• A61B 5/16 - Devices for psychotechnicsTesting reaction times
• A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The present invention is directed to method of determining whether a subject is at risk of developing insulin resistance, particularly for advance alert of T2D and or CVD onset in obese and non-obese subject, by detecting the branched-chain amino acids (BCAAs) present in an urine sample (uBCAAs) of the subjects. The present invention also relates to a method for determining the need of a dietary/nutritional supplement for a subject involving said uBCAAs biomarkers. Finally, the invention is directed to kit comprising the biochemical network allowing the uBCAAs detection and process for the preparation of said biochemical networks as diagnostic biomarker.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The present invention is directed to biodegradable biochemical sensor method to perform in a sample multiplex detection and/or quantification of pesticides and/or endocrine disruptors and to provide and logical integrated response to the user. This biochemical sensor is a vesicle encapsulating biochemical networks using enzymes capable of generating, inhibiting or activating specific measurable signal in presence of said target analytes. The biochemical network is able to provide an integrated logical final response to the user. The present invention also relates to a composition or kit comprising said biochemical sensor vesicle.

IPC Classes  ?

• C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
• C12Q 1/48 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving transferase

Abstract

The present invention is directed to a method for the detection of SARS-CoV-2 virus (COVID19 virus) based on reverse transcription loop-mediated isothermal amplification (RT-LAMP) designed to amplify specifically a sequence of SARS-CoV- 2 gene fragment using a set of specially designed RT-LAMP primers. The present invention also relates to a kit for specifically detecting said sequence of of SARS-CoV- 2 gene fragment comprising the set of specially designed RT-LAMP primers according to the present invention.

IPC Classes  ?

• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage

Goods & Services

Diagnostic preparations, other than for medical or veterinary purposes; Biological preparations, other than for medical or veterinary purposes. Biological preparations for medical purposes; Biological preparations for veterinary purposes; Chemico-pharmaceutical preparations; Chemical preparations for pharmaceutical purposes; Diagnostic preparations for medical purposes; Enzyme preparations for medical purposes; Enzyme preparations for veterinary purposes. Chemical research; Conducting technical project studies; Biological research.

Goods & Services

Biological preparations for medical use, diagnostic preparations for medical use, enzymatic preparations for medical use.

Abstract

The present invention is directed to biodegradable biochemical sensor method to perform in a sample multiplex detection and/or quantification of pesticides and/or endocrine disruptors and to provide and logical integrated response to the user. This biochemical sensor is a vesicle encapsulating biochemical networks using enzymes capable of generating, inhibiting or activating specific measurable signal in presence of said target analytes. The biochemical network is able to provide an integrated logical final response to the user. The present invention also relates to a composition or kit comprising said biochemical sensor vesicle.

IPC Classes  ?

• C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
• C12Q 1/28 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase involving peroxidase
• C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
• C12Q 1/42 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving phosphatase
• C12Q 1/44 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving esterase
• C12Q 1/46 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving esterase involving cholinesterase

Goods & Services

Biological preparations for medical purposes, Diagnostic preparations for medical purposes, Enzyme preparations for medical purposes.

Abstract

The present invention is directed to a method for the preparation of a non-living micro/nanoscale biosynthetic device capable of giving an information of a state of a system to analyse. Preferably, said device is used as an assay diagnostic, or to predict the risk, of a disease, or for the classification of mammal, preferably human pathologies. The invention also relates to a method for the identification and/or the quantification of a compound in a sample. Finally the present invention includes a kit comprising the biosynthetic device obtained by the method of the present invention.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
• B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/573 - ImmunoassayBiospecific binding assayMaterials therefor for enzymes or isoenzymes
• G06N 3/00 - Computing arrangements based on biological models
• G16C 99/00 - Subject matter not provided for in other groups of this subclass

Abstract

The present invention is directed to a method for the preparation of a non-living micro/nanoscale biosynthetic device capable of giving an information of a state of a system to analyse. Preferably, said device is used as an assay diagnostic, or to predict the risk, of a disease, or for the classification of mammal, preferably human pathologies. The invention also relates to a method for the identification and/or the quantification of a compound in a sample. Finally the present invention includes a kit comprising the biosynthetic device obtained by the method of the present invention.

IPC Classes  ?

• G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
• B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
• B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
• B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors