Abstract

The present invention relates to a process for preparing 2,6-susbstituted phenols, and in particular to a process for preparing 2,6-diphenylphenol. This process is a doubling coupling of a boronic acid and a 2,6-dihalogenphenol in a Suzuki-Miyaura reaction on sterically hindered ortho positions. In a preferred embodiment, this process takes place in a continuous flow system. The present invention further relates to the composition obtained by this process, and to the use of this composition for preparing poly(2,6-diphenylphenylene oxide), for the manufacture of dyes, drugs, plastics, insulating materials and/or insecticides, and for use in medical applications and material research.

IPC Classes  ?

• C07C 37/11 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
• C07C 37/18 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by condensation involving halogen atoms of halogenated compounds